MRNA knockdown by single strand RNA is improved by chemical modifications

Nucleic Acids Research

Volumn 40, Issue 9, 2012, Pages 4125-4136

  Haringsma, Henry J ^a   Li, Jenny J ^a   Soriano, Ferdie ^a   Kenski, Denise M ^a   Flanagan, W Michael ^a   Willingham, Aarron T ^a  

^a Sirna Therapeutics Inc   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOLIPOPROTEIN B; ARGONAUTE 2 PROTEIN; MESSENGER RNA; SINGLE STRANDED RNA; SMALL INTERFERING RNA; SOLID LIPID NANOPARTICLE;

ANIMAL CELL; ANIMAL EXPERIMENT; APOB GENE; ARTICLE; CHEMICAL MODIFICATION; CONTROLLED STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; GENE; GENE EXPRESSION REGULATION; GENE SILENCING; GENE TARGETING; IN VITRO STUDY; IN VIVO STUDY; LIPOSOMAL DELIVERY; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PHOSPHORYLATION; PRIORITY JOURNAL; PROCESS OPTIMIZATION; RNA CLEAVAGE; RNA INTERFERENCE; RNA SEQUENCE; SSB GENE;

ANIMALS; ARGONAUTE PROTEINS; CELL LINE; MICE; MICE, INBRED C57BL; PHOSPHORYLATION; RNA INTERFERENCE; RNA, MESSENGER; RNA, SMALL INTERFERING; RNA, SMALL UNTRANSLATED;

EID: 84861380461     PISSN: 03051048     EISSN: 13624962     Source Type: Journal    
DOI: 10.1093/nar/gkr1301     Document Type: Article

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