-
1
-
-
3042767202
-
MicroRNAs: small RNAs with a big role in gene regulation
-
He L., and Hannon G.J. MicroRNAs: small RNAs with a big role in gene regulation. Nat. Rev. Genet. 5 (2004) 522-531
-
(2004)
Nat. Rev. Genet.
, vol.5
, pp. 522-531
-
-
He, L.1
Hannon, G.J.2
-
2
-
-
0036308857
-
RNA interference: antiviral defense and genetic tool
-
Cullen B.R. RNA interference: antiviral defense and genetic tool. Nat. Immunol. 3 (2002) 597-599
-
(2002)
Nat. Immunol.
, vol.3
, pp. 597-599
-
-
Cullen, B.R.1
-
3
-
-
0035887005
-
Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans
-
Ketting R.F., Fischer S.E., Bernstein E., Sijen T., Hannon G.J., and Plasterk R.H. Dicer functions in RNA interference and in synthesis of small RNA involved in developmental timing in C. elegans. Genes. Dev. 15 (2001) 2654-2659
-
(2001)
Genes. Dev.
, vol.15
, pp. 2654-2659
-
-
Ketting, R.F.1
Fischer, S.E.2
Bernstein, E.3
Sijen, T.4
Hannon, G.J.5
Plasterk, R.H.6
-
4
-
-
0035905766
-
Role for a bidentate ribonuclease in the initiation step of RNA interference
-
Bernstein E., Caudy A.A., Hammond S.M., and Hannon G.J. Role for a bidentate ribonuclease in the initiation step of RNA interference. Nature 409 (2001) 363-366
-
(2001)
Nature
, vol.409
, pp. 363-366
-
-
Bernstein, E.1
Caudy, A.A.2
Hammond, S.M.3
Hannon, G.J.4
-
5
-
-
1842816517
-
Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways
-
Lee Y.S., Nakahara K., Pham J.W., Kim K., He Z., Sontheimer E.J., and Carthew R.W. Distinct roles for Drosophila Dicer-1 and Dicer-2 in the siRNA/miRNA silencing pathways. Cell 117 (2004) 69-81
-
(2004)
Cell
, vol.117
, pp. 69-81
-
-
Lee, Y.S.1
Nakahara, K.2
Pham, J.W.3
Kim, K.4
He, Z.5
Sontheimer, E.J.6
Carthew, R.W.7
-
6
-
-
26944441255
-
Dicing and slicing: the core machinery of the RNA interference pathway
-
Hammond S.M. Dicing and slicing: the core machinery of the RNA interference pathway. FEBS Lett. 579 (2005) 5822-5829
-
(2005)
FEBS Lett.
, vol.579
, pp. 5822-5829
-
-
Hammond, S.M.1
-
8
-
-
33750990797
-
DUF283 domain of Dicer proteins has a double-stranded RNA-binding fold
-
Dlakic M. DUF283 domain of Dicer proteins has a double-stranded RNA-binding fold. Bioinformatics 22 (2006) 2711-2714
-
(2006)
Bioinformatics
, vol.22
, pp. 2711-2714
-
-
Dlakic, M.1
-
9
-
-
0037009364
-
MicroRNA maturation: stepwise processing and subcellular localization
-
Lee Y., Jeon K., Lee J.T., Kim S., and Kim V.N. MicroRNA maturation: stepwise processing and subcellular localization. EMBO J. 21 (2002) 4663-4670
-
(2002)
EMBO J.
, vol.21
, pp. 4663-4670
-
-
Lee, Y.1
Jeon, K.2
Lee, J.T.3
Kim, S.4
Kim, V.N.5
-
10
-
-
3142613181
-
Single processing center models for human Dicer and bacterial RNaseIII
-
Zhang H., Kolb F.A., Jaskiewicz L., Westhof E., and Filipowicz W. Single processing center models for human Dicer and bacterial RNaseIII. Cell 118 (2004) 57-68
-
(2004)
Cell
, vol.118
, pp. 57-68
-
-
Zhang, H.1
Kolb, F.A.2
Jaskiewicz, L.3
Westhof, E.4
Filipowicz, W.5
-
11
-
-
1242318826
-
Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing
-
Meister G., Landthaler M., Dorsett Y., and Tuschl T. Sequence-specific inhibition of microRNA- and siRNA-induced RNA silencing. RNA 10 (2004) 544-550
-
(2004)
RNA
, vol.10
, pp. 544-550
-
-
Meister, G.1
Landthaler, M.2
Dorsett, Y.3
Tuschl, T.4
-
12
-
-
18744407284
-
Purified Argonaute2 and an siRNA form recombinant human RISC
-
Rivas F.V., Tolia N.H., Song J.J., Aragon J.P., Liu J., Hannon G.J., and Joshua-Tor L. Purified Argonaute2 and an siRNA form recombinant human RISC. Nat. Struct. Mol. Biol. 12 (2005) 340-349
-
(2005)
Nat. Struct. Mol. Biol.
, vol.12
, pp. 340-349
-
-
Rivas, F.V.1
Tolia, N.H.2
Song, J.J.3
Aragon, J.P.4
Liu, J.5
Hannon, G.J.6
Joshua-Tor, L.7
-
13
-
-
28444437427
-
Slicer function of Drosophila argonautes and its involvement in RISC formation
-
Miyoshi K., Tsukumo H., Nagami T., Siomi H., and Siomi M.C. Slicer function of Drosophila argonautes and its involvement in RISC formation. Genes Dev. 19 (2005) 2837-2848
-
(2005)
Genes Dev.
, vol.19
, pp. 2837-2848
-
-
Miyoshi, K.1
Tsukumo, H.2
Nagami, T.3
Siomi, H.4
Siomi, M.C.5
-
14
-
-
20444427566
-
Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies
-
Sen G.L., and Blau H.M. Argonaute 2/RISC resides in sites of mammalian mRNA decay known as cytoplasmic bodies. Nat. Cell Biol. 7 (2005) 633-636
-
(2005)
Nat. Cell Biol.
, vol.7
, pp. 633-636
-
-
Sen, G.L.1
Blau, H.M.2
-
15
-
-
17844363243
-
The contributions of dsRNA structure to Dicer specificity and efficiency
-
Vermeulen A., Behlen L., Reynolds A., Wolfson A., Marshall W.S., Karpilow J., and Khvorova A. The contributions of dsRNA structure to Dicer specificity and efficiency. RNA 11 (2005) 674-682
-
(2005)
RNA
, vol.11
, pp. 674-682
-
-
Vermeulen, A.1
Behlen, L.2
Reynolds, A.3
Wolfson, A.4
Marshall, W.S.5
Karpilow, J.6
Khvorova, A.7
-
16
-
-
34948901976
-
Structural determinants of RNA recognition and cleavage by Dicer
-
MacRae I.J., Zhou K., and Doudna J.A. Structural determinants of RNA recognition and cleavage by Dicer. Nat. Struct. Mol. Biol. 14 (2007) 934-940
-
(2007)
Nat. Struct. Mol. Biol.
, vol.14
, pp. 934-940
-
-
MacRae, I.J.1
Zhou, K.2
Doudna, J.A.3
-
17
-
-
4444302947
-
Crystal structure of Argonaute and its implications for RISC slicer activity
-
Song J.J., Smith S.K., Hannon G.J., and Joshua-Tor L. Crystal structure of Argonaute and its implications for RISC slicer activity. Science 305 (2004) 1434-1437
-
(2004)
Science
, vol.305
, pp. 1434-1437
-
-
Song, J.J.1
Smith, S.K.2
Hannon, G.J.3
Joshua-Tor, L.4
-
19
-
-
0345359925
-
Structure and nucleic-acid binding of the Drosophila argonaute 2 PAZ domain
-
Lingel A., Simon B., Izaurralde E., and Sattler M. Structure and nucleic-acid binding of the Drosophila argonaute 2 PAZ domain. Nature 426 (2003) 465-469
-
(2003)
Nature
, vol.426
, pp. 465-469
-
-
Lingel, A.1
Simon, B.2
Izaurralde, E.3
Sattler, M.4
-
20
-
-
0642345790
-
Structure and conserved RNA binding of the PAZ domain
-
Yan K.S., Yan S., Farooq A., Han A., Zeng L., and Zhou M.M. Structure and conserved RNA binding of the PAZ domain. Nature 426 (2003) 469-474
-
(2003)
Nature
, vol.426
, pp. 469-474
-
-
Yan, K.S.1
Yan, S.2
Farooq, A.3
Han, A.4
Zeng, L.5
Zhou, M.M.6
-
21
-
-
0042121256
-
Mfold web server for nucleic acid folding and hybridization prediction
-
Zuker M. Mfold web server for nucleic acid folding and hybridization prediction. Nucleic Acids Res. 31 (2003) 3406-3415
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 3406-3415
-
-
Zuker, M.1
-
22
-
-
0033591465
-
Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure
-
Mathews D.H., Sabina J., Zuker M., and Turner D.H. Expanded sequence dependence of thermodynamic parameters improves prediction of RNA secondary structure. J. Mol. Biol. 288 (1999) 911-940
-
(1999)
J. Mol. Biol.
, vol.288
, pp. 911-940
-
-
Mathews, D.H.1
Sabina, J.2
Zuker, M.3
Turner, D.H.4
-
23
-
-
0036845374
-
Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP
-
Zhang H., Kolb F.A., Brondani V., Billy E., and Filipowicz W. Human Dicer preferentially cleaves dsRNAs at their termini without a requirement for ATP. EMBO J. 21 (2002) 5875-5885
-
(2002)
EMBO J.
, vol.21
, pp. 5875-5885
-
-
Zhang, H.1
Kolb, F.A.2
Brondani, V.3
Billy, E.4
Filipowicz, W.5
-
24
-
-
0036847540
-
Ribonuclease activity and RNA binding of recombinant human Dicer
-
Provost P., Dishart D., Doucet J., Frendewey D., Samuelsson B., and Radmark O. Ribonuclease activity and RNA binding of recombinant human Dicer. EMBO J. 21 (2002) 5864-5874
-
(2002)
EMBO J.
, vol.21
, pp. 5864-5874
-
-
Provost, P.1
Dishart, D.2
Doucet, J.3
Frendewey, D.4
Samuelsson, B.5
Radmark, O.6
-
25
-
-
27144469457
-
ATP modulates siRNA interactions with an endogenous human Dicer complex
-
Pellino J.L., Jaskiewicz L., Filipowicz W., and Sontheimer E.J. ATP modulates siRNA interactions with an endogenous human Dicer complex. RNA 11 (2005) 1719-1724
-
(2005)
RNA
, vol.11
, pp. 1719-1724
-
-
Pellino, J.L.1
Jaskiewicz, L.2
Filipowicz, W.3
Sontheimer, E.J.4
-
26
-
-
23644433363
-
TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing
-
Chendrimada T.P., Gregory R.I., Kumaraswamy E., Norman J., Cooch N., Nishikura K., and Shiekhattar R. TRBP recruits the Dicer complex to Ago2 for microRNA processing and gene silencing. Nature 436 (2005) 740-744
-
(2005)
Nature
, vol.436
, pp. 740-744
-
-
Chendrimada, T.P.1
Gregory, R.I.2
Kumaraswamy, E.3
Norman, J.4
Cooch, N.5
Nishikura, K.6
Shiekhattar, R.7
-
27
-
-
0027650811
-
Native protein separations and enzyme microassays by capillary zone and gel electrophoresis
-
Wu D., and Regnier F.E. Native protein separations and enzyme microassays by capillary zone and gel electrophoresis. Anal. Chem. 65 (1993) 2029-2035
-
(1993)
Anal. Chem.
, vol.65
, pp. 2029-2035
-
-
Wu, D.1
Regnier, F.E.2
-
28
-
-
30844438338
-
Structural basis for double-stranded RNA processing by Dicer
-
MacRae I.J., Zhou K., Li F., Repic A., Brooks A.N., Cande W.Z., Adams P.D., and Doudna J.A. Structural basis for double-stranded RNA processing by Dicer. Science 311 (2006) 195-198
-
(2006)
Science
, vol.311
, pp. 195-198
-
-
MacRae, I.J.1
Zhou, K.2
Li, F.3
Repic, A.4
Brooks, A.N.5
Cande, W.Z.6
Adams, P.D.7
Doudna, J.A.8
-
29
-
-
0029976320
-
Defining the enzyme binding domain of a ribonuclease III processing signal. Ethylation interference and hydroxyl radical footprinting using catalytically inactive RNaseIII mutants
-
Li H., and Nicholson A.W. Defining the enzyme binding domain of a ribonuclease III processing signal. Ethylation interference and hydroxyl radical footprinting using catalytically inactive RNaseIII mutants. EMBO J. 15 (1996) 1421-1433
-
(1996)
EMBO J.
, vol.15
, pp. 1421-1433
-
-
Li, H.1
Nicholson, A.W.2
-
30
-
-
34248563036
-
The human RNA kinase hClp1 is active on 3′ transfer RNA exons and short interfering RNAs
-
Weitzer S., and Martinez J. The human RNA kinase hClp1 is active on 3′ transfer RNA exons and short interfering RNAs. Nature 447 (2007) 222-226
-
(2007)
Nature
, vol.447
, pp. 222-226
-
-
Weitzer, S.1
Martinez, J.2
-
31
-
-
0035798415
-
ATP requirements and small interfering RNA structure in the RNA interference pathway
-
Nykanen A., Haley B., and Zamore P.D. ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell 107 (2001) 309-321
-
(2001)
Cell
, vol.107
, pp. 309-321
-
-
Nykanen, A.1
Haley, B.2
Zamore, P.D.3
-
32
-
-
13844280638
-
Synthetic shRNAs as potent RNAi triggers
-
Siolas D., Lerner C., Burchard J., Ge W., Linsley P.S., Paddison P.J., Hannon G.J., and Cleary M.A. Synthetic shRNAs as potent RNAi triggers. Nat. Biotechnol. 23 (2005) 227-231
-
(2005)
Nat. Biotechnol.
, vol.23
, pp. 227-231
-
-
Siolas, D.1
Lerner, C.2
Burchard, J.3
Ge, W.4
Linsley, P.S.5
Paddison, P.J.6
Hannon, G.J.7
Cleary, M.A.8
-
33
-
-
13844312491
-
Catalytic mechanism of Escherichia coli ribonuclease III: kinetic and inhibitor evidence for the involvement of two magnesium ions in RNA phosphodiester hydrolysis
-
Sun W., Pertzev A., and Nicholson A.W. Catalytic mechanism of Escherichia coli ribonuclease III: kinetic and inhibitor evidence for the involvement of two magnesium ions in RNA phosphodiester hydrolysis. Nucleic Acids Res. 33 (2005) 807-815
-
(2005)
Nucleic Acids Res.
, vol.33
, pp. 807-815
-
-
Sun, W.1
Pertzev, A.2
Nicholson, A.W.3
-
34
-
-
33746461896
-
Structural basis for non-catalytic and catalytic activities of ribonuclease III
-
Ji X. Structural basis for non-catalytic and catalytic activities of ribonuclease III. Acta. Crystallogr. D. Biol. Crystallogr. 62 (2006) 933-940
-
(2006)
Acta. Crystallogr. D. Biol. Crystallogr.
, vol.62
, pp. 933-940
-
-
Ji, X.1
-
35
-
-
0036752955
-
Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways
-
Schwarz D.S., Hutvagner G., Haley B., and Zamore P.D. Evidence that siRNAs function as guides, not primers, in the Drosophila and human RNAi pathways. Mol. Cell 10 (2002) 537-548
-
(2002)
Mol. Cell
, vol.10
, pp. 537-548
-
-
Schwarz, D.S.1
Hutvagner, G.2
Haley, B.3
Zamore, P.D.4
-
36
-
-
0038074374
-
Similar behaviour of single-strand and double-strand siRNAs suggests they act through a common RNAi pathway
-
Holen T., Amarzguioui M., Babaie E., and Prydz H. Similar behaviour of single-strand and double-strand siRNAs suggests they act through a common RNAi pathway. Nucleic Acids Res. 31 (2003) 2401-2407
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 2401-2407
-
-
Holen, T.1
Amarzguioui, M.2
Babaie, E.3
Prydz, H.4
-
37
-
-
34547115237
-
Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA
-
Kok K.H., Ng M.H., Ching Y.P., and Jin D.Y. Human TRBP and PACT directly interact with each other and associate with dicer to facilitate the production of small interfering RNA. J. Biol. Chem. 282 (2007) 17649-17657
-
(2007)
J. Biol. Chem.
, vol.282
, pp. 17649-17657
-
-
Kok, K.H.1
Ng, M.H.2
Ching, Y.P.3
Jin, D.Y.4
-
38
-
-
33745402414
-
A novel class of small RNAs bind to MILI protein in mouse testes
-
Aravin A., et al. A novel class of small RNAs bind to MILI protein in mouse testes. Nature 442 (2006) 203-207
-
(2006)
Nature
, vol.442
, pp. 203-207
-
-
Aravin, A.1
-
39
-
-
33846927800
-
Ribonuclease revisited: structural insights into ribonuclease III family enzymes
-
MacRae I.J., and Doudna J.A. Ribonuclease revisited: structural insights into ribonuclease III family enzymes. Curr. Opin. Struct. Biol. 17 (2007) 138-145
-
(2007)
Curr. Opin. Struct. Biol.
, vol.17
, pp. 138-145
-
-
MacRae, I.J.1
Doudna, J.A.2
-
40
-
-
34247525481
-
piRNAs in the germ line
-
Lin H. piRNAs in the germ line. Science 316 (2007) 397
-
(2007)
Science
, vol.316
, pp. 397
-
-
Lin, H.1
-
41
-
-
0032535613
-
Molecular basis of double-stranded RNA-protein interactions: structure of a dsRNA-binding domain complexed with dsRNA
-
Ryter J.M., and Schultz S.C. Molecular basis of double-stranded RNA-protein interactions: structure of a dsRNA-binding domain complexed with dsRNA. EMBO J. 17 (1998) 7505-7513
-
(1998)
EMBO J.
, vol.17
, pp. 7505-7513
-
-
Ryter, J.M.1
Schultz, S.C.2
-
42
-
-
0032485912
-
Binding of the protein kinase PKR to RNAs with secondary structure defects: role of the tandem A-G mismatch and noncontiguous helixes
-
Bevilacqua P.C., George C.X., Samuel C.E., and Cech T.R. Binding of the protein kinase PKR to RNAs with secondary structure defects: role of the tandem A-G mismatch and noncontiguous helixes. Biochemistry 37 (1998) 6303-6316
-
(1998)
Biochemistry
, vol.37
, pp. 6303-6316
-
-
Bevilacqua, P.C.1
George, C.X.2
Samuel, C.E.3
Cech, T.R.4
|