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Volumn 16, Issue 12, 2010, Pages 2553-2563

Quantitative evaluation of siRNA delivery in vivo

Author keywords

Argonaute 2; In vivo delivery; RISC; siRNA

Indexed keywords

SMALL INTERFERING RNA;

EID: 78649683035     PISSN: 13558382     EISSN: 14699001     Source Type: Journal    
DOI: 10.1261/rna.2255810     Document Type: Article
Times cited : (66)

References (46)
  • 2
    • 34447102459 scopus 로고    scopus 로고
    • Molecular basis for target RNA recognition and cleavage by human RISC
    • Ameres SL, Martinez J, Schroeder R. 2007. Molecular basis for target RNA recognition and cleavage by human RISC. Cell 130: 101-112.
    • (2007) Cell , vol.130 , pp. 101-112
    • Ameres, S.L.1    Martinez, J.2    Schroeder, R.3
  • 4
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP. 2009. MicroRNAs: Target recognition and regulatory functions. Cell 136: 215-233.
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 5
    • 37649021046 scopus 로고    scopus 로고
    • Identification of human microRNA targets from isolated Argonaute protein complexes
    • Beitzinger M, Peters L, Zhu JY, Kremmer E, Meister G. 2007. Identification of human microRNA targets from isolated Argonaute protein complexes. RNA Biol 4: 76-84.
    • (2007) RNA Biol , vol.4 , pp. 76-84
    • Beitzinger, M.1    Peters, L.2    Zhu, J.Y.3    Kremmer, E.4    Meister, G.5
  • 6
    • 0036828639 scopus 로고    scopus 로고
    • The Argonaute family: Tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis
    • DOI 10.1101/gad.1026102
    • Carmell MA, Xuan Z, Zhang MQ, Hannon GJ. 2002. The Argonaute family: Tentacles that reach into RNAi, developmental control, stem cell maintenance, and tumorigenesis. Genes & Dev 16: 2733-2742. (Pubitemid 35253139)
    • (2002) Genes and Development , vol.16 , Issue.21 , pp. 2733-2742
    • Carmell, M.A.1    Xuan, Z.2    Zhang, M.Q.3    Hannon, G.J.4
  • 7
    • 60149088848 scopus 로고    scopus 로고
    • Origins and mechanisms of miRNAs and siRNAs
    • Carthew RW, Sontheimer EJ. 2009. Origins and mechanisms of miRNAs and siRNAs. Cell 136: 642-655.
    • (2009) Cell , vol.136 , pp. 642-655
    • Carthew, R.W.1    Sontheimer, E.J.2
  • 8
    • 58749104364 scopus 로고    scopus 로고
    • The promises and pitfalls of RNA-interference-based therapeutics
    • Castanotto D, Rossi JJ. 2009. The promises and pitfalls of RNA-interference-based therapeutics. Nature 457: 426-433.
    • (2009) Nature , vol.457 , pp. 426-433
    • Castanotto, D.1    Rossi, J.J.2
  • 10
    • 23844523406 scopus 로고    scopus 로고
    • MiR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1
    • Chang J, Nicolas E, Marks D, Sander C, Lerro A, Buendia MA, Xu C, Mason WS, Moloshok T, Bort R, et al. 2004. miR-122, a mammalian liver-specific microRNA, is processed from hcr mRNA and may downregulate the high affinity cationic amino acid transporter CAT-1. RNA Biol 1: 106-113.
    • (2004) RNA Biol , vol.1 , pp. 106-113
    • Chang, J.1    Nicolas, E.2    Marks, D.3    Sander, C.4    Lerro, A.5    Buendia, M.A.6    Xu, C.7    Mason, W.S.8    Moloshok, T.9    Bort, R.10
  • 11
    • 70349453924 scopus 로고    scopus 로고
    • Active turnover modulates mature microRNA activity in Caenorhabditis elegans
    • Chatterjee S, Grosshans H. 2009. Active turnover modulates mature microRNA activity in Caenorhabditis elegans. Nature 461: 546-549.
    • (2009) Nature , vol.461 , pp. 546-549
    • Chatterjee, S.1    Grosshans, H.2
  • 13
    • 38649099969 scopus 로고    scopus 로고
    • Strand-specific 5′-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity
    • Chen PY, Weinmann L, Gaidatzis D, Pei Y, Zavolan M, Tuschl T, Meister G. 2008. Strand-specific 5′-O-methylation of siRNA duplexes controls guide strand selection and targeting specificity. RNA 14: 263-274.
    • (2008) RNA , vol.14 , pp. 263-274
    • Chen, P.Y.1    Weinmann, L.2    Gaidatzis, D.3    Pei, Y.4    Zavolan, M.5    Tuschl, T.6    Meister, G.7
  • 16
    • 43049096410 scopus 로고    scopus 로고
    • The growing catalog of small RNAs and their association with distinct Argonaute/Piwi family members
    • DOI 10.1242/dev.005629
    • Farazi TA, Juranek SA, Tuschl T. 2008. The growing catalog of small RNAs and their association with distinct Argonaute/Piwi family members. Development 135: 1201-1214. (Pubitemid 351622465)
    • (2008) Development , vol.135 , Issue.7 , pp. 1201-1214
    • Farazi, T.A.1    Juranek, S.A.2    Tuschl, T.3
  • 17
    • 58449134534 scopus 로고    scopus 로고
    • Small silencing RNAs: An expanding universe
    • Ghildiyal M, Zamore PD. 2009. Small silencing RNAs: An expanding universe. Nat Rev Genet 10: 94-108.
    • (2009) Nat Rev Genet , vol.10 , pp. 94-108
    • Ghildiyal, M.1    Zamore, P.D.2
  • 18
    • 19344378192 scopus 로고    scopus 로고
    • Sequence-specific inhibition of small RNA function
    • doi: 10.1371/journal.pbio.0020098
    • Hutvágner G, Simard MJ, Mello CC, Zamore PD. 2004. Sequence-specific inhibition of small RNA function. PLoS Biol 2: E98. doi: 10.1371/journal.pbio.0020098.
    • (2004) PLoS Biol , vol.2
    • Hutvágner, G.1    Simard, M.J.2    Mello, C.C.3    Zamore, P.D.4
  • 19
    • 66349094564 scopus 로고    scopus 로고
    • Cell-cell contact globally activates microRNA biogenesis
    • Hwang HW, Wentzel EA, Mendell JT. 2009. Cell-cell contact globally activates microRNA biogenesis. Proc Natl Acad Sci 106: 7016-7021.
    • (2009) Proc Natl Acad Sci , vol.106 , pp. 7016-7021
    • Hwang, H.W.1    Wentzel, E.A.2    Mendell, J.T.3
  • 20
    • 58749113430 scopus 로고    scopus 로고
    • A three-dimensional view of the molecular machinery of RNA interference
    • Jinek M, Doudna JA. 2009. A three-dimensional view of the molecular machinery of RNA interference. Nature 457: 405-412.
    • (2009) Nature , vol.457 , pp. 405-412
    • Jinek, M.1    Doudna, J.A.2
  • 22
    • 67149115119 scopus 로고    scopus 로고
    • Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs
    • Khan AA, Betel D, Miller ML, Sander C, Leslie CS, Marks DS. 2009. Transfection of small RNAs globally perturbs gene regulation by endogenous microRNAs. Nat Biotechnol 27: 549-555.
    • (2009) Nat Biotechnol , vol.27 , pp. 549-555
    • Khan, A.A.1    Betel, D.2    Miller, M.L.3    Sander, C.4    Leslie, C.S.5    Marks, D.S.6
  • 27
    • 35348861314 scopus 로고    scopus 로고
    • Cellular uptake and intracellular release are major obstacles to the therapeutic application of siRNA: Novel options by phosphorothioate-stimulated delivery
    • Mescalchin A, Detzer A, Wecke M, Overhoff M, Wunsche W, Sczakiel G. 2007. Cellular uptake and intracellular release are major obstacles to the therapeutic application of siRNA: Novel options by phosphorothioate-stimulated delivery. Expert Opin Biol Ther 7: 1531-1538.
    • (2007) Expert Opin Biol Ther , vol.7 , pp. 1531-1538
    • Mescalchin, A.1    Detzer, A.2    Wecke, M.3    Overhoff, M.4    Wunsche, W.5    Sczakiel, G.6
  • 28
    • 7044272280 scopus 로고    scopus 로고
    • Evidence for reassociation of RNA-binding proteins after cell lysis: Implications for the interpretation of immunoprecipitation analyses
    • Mili S, Steitz JA. 2004. Evidence for reassociation of RNA-binding proteins after cell lysis: Implications for the interpretation of immunoprecipitation analyses. RNA 10: 1692-1694.
    • (2004) RNA , vol.10 , pp. 1692-1694
    • Mili, S.1    Steitz, J.A.2
  • 30
    • 74049153383 scopus 로고    scopus 로고
    • Systemic delivery and quantification of unformulated interfering RNAs in vivo
    • Morin A, Gallou-Kabani C, Mathieu JR, Cabon F. 2009. Systemic delivery and quantification of unformulated interfering RNAs in vivo. Curr Top Med Chem 9: 1117-1129.
    • (2009) Curr Top Med Chem , vol.9 , pp. 1117-1129
    • Morin, A.1    Gallou-Kabani, C.2    Mathieu, J.R.3    Cabon, F.4
  • 32
    • 0035798415 scopus 로고    scopus 로고
    • ATP requirements and small interfering RNA structure in the RNA interference pathway
    • DOI 10.1016/S0092-8674(01)00547-5
    • Nykanen A, Haley B, Zamore PD. 2001. ATP requirements and small interfering RNA structure in the RNA interference pathway. Cell 107: 309-321. (Pubitemid 33049975)
    • (2001) Cell , vol.107 , Issue.3 , pp. 309-321
    • Nykanen, A.1    Haley, B.2    Zamore, P.D.3
  • 33
    • 38849166053 scopus 로고    scopus 로고
    • Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target
    • DOI 10.1126/science.1149859
    • Peer D, Park EJ, Morishita Y, Carman CV, Shimaoka M. 2008. Systemic leukocyte-directed siRNA delivery revealing cyclin D1 as an anti-inflammatory target. Science 319: 627-630. (Pubitemid 351197066)
    • (2008) Science , vol.319 , Issue.5863 , pp. 627-630
    • Peer, D.1    Eun, J.P.2    Morishita, Y.3    Carman, C.V.4    Shimaoka, M.5
  • 34
    • 10744225153 scopus 로고    scopus 로고
    • Asymmetry in the assembly of the RNAi enzyme complex
    • DOI 10.1016/S0092-8674(03)00759-1
    • Schwarz DS, Hutvagner G, Du T, Xu Z, Aronin N, Zamore PD. 2003. Asymmetry in the assembly of the RNAi enzyme complex. Cell 115: 199-208. (Pubitemid 37329583)
    • (2003) Cell , vol.115 , Issue.2 , pp. 199-208
    • Schwarz, D.S.1    Hutvagner, G.2    Du, T.3    Xu, Z.4    Aronin, N.5    Zamore, P.D.6
  • 35
    • 54249139512 scopus 로고    scopus 로고
    • Challenges and opportunities for local and systemic delivery of siRNA and antisense oligonucleotides
    • Sepp-Lorenzino L, Ruddy M. 2008. Challenges and opportunities for local and systemic delivery of siRNA and antisense oligonucleotides. Clin Pharmacol Ther 84: 628-632.
    • (2008) Clin Pharmacol Ther , vol.84 , pp. 628-632
    • Sepp-Lorenzino, L.1    Ruddy, M.2
  • 36
    • 46549083921 scopus 로고    scopus 로고
    • Examination of real-time polymerase chain reaction methods for the detection and quantification of modified siRNA
    • Stratford S, Stec S, Jadhav V, Seitzer J, Abrams M, Beverly M. 2008. Examination of real-time polymerase chain reaction methods for the detection and quantification of modified siRNA. Anal Biochem 379: 96-104.
    • (2008) Anal Biochem , vol.379 , pp. 96-104
    • Stratford, S.1    Stec, S.2    Jadhav, V.3    Seitzer, J.4    Abrams, M.5    Beverly, M.6
  • 40
    • 33845873577 scopus 로고    scopus 로고
    • Cellular delivery of small interfering RNA by a non-covalently attached cell-penetrating peptide: Quantitative analysis of uptake and biological effect
    • DOI 10.1093/nar/gkl941
    • Veldhoen S, Laufer SD, Trampe A, Restle T. 2006. Cellular delivery of small interfering RNA by a non-covalently attached cell-penetrating peptide: Quantitative analysis of uptake and biological effect. Nucleic Acids Res 34: 6561-6573. (Pubitemid 46017951)
    • (2006) Nucleic Acids Research , vol.34 , Issue.22 , pp. 6561-6573
    • Veldhoen, S.1    Laufer, S.D.2    Trampe, A.3    Restle, T.4
  • 41
    • 71449095148 scopus 로고    scopus 로고
    • Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins
    • Wang B, Li S, Qi HH, Chowdhury D, Shi Y, Novina CD. 2009. Distinct passenger strand and mRNA cleavage activities of human Argonaute proteins. Nat Struct Mol Biol 16: 1259-1266.
    • (2009) Nat Struct Mol Biol , vol.16 , pp. 1259-1266
    • Wang, B.1    Li, S.2    Qi, H.H.3    Chowdhury, D.4    Shi, Y.5    Novina, C.D.6
  • 45
    • 50849117820 scopus 로고    scopus 로고
    • Importance of translation and nonnucleolytic ago proteins for on-target RNA interference
    • Wu L, Fan J, Belasco JG. 2008. Importance of translation and nonnucleolytic ago proteins for on-target RNA interference. Curr Biol 18: 1327-1332.
    • (2008) Curr Biol , vol.18 , pp. 1327-1332
    • Wu, L.1    Fan, J.2    Belasco, J.G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.