-
1
-
-
44249094435
-
Microbial host interactions in IBD: Implications for pathogenesis and therapy
-
DOI 10.1007/s11894-007-0066-4
-
Sartor RB, Muehlbauer M. Microbial host interactions in IBD: implications for pathogenesis and therapy. Curr Gastroenterol Rep. 2007;9(6):497-507. (Pubitemid 351795708)
-
(2007)
Current Gastroenterology Reports
, vol.9
, Issue.6
, pp. 497-507
-
-
Sartor, R.B.1
Muehlbauer, M.2
-
2
-
-
0000721464
-
Lymphoid tissue and serum gamma globulin in young germfree chickens
-
Nov-Dec
-
Thorbecke GJ, Gordon HA, Wostman B, Wagner M, Reyniers JA. Lymphoid tissue and serum gamma globulin in young germfree chickens. J Infect Dis Nov-Dec. 1957;101(3):237-51.
-
(1957)
J Infect Dis
, vol.101
, Issue.3
, pp. 237-251
-
-
Thorbecke, G.J.1
Gordon, H.A.2
Wostman, B.3
Wagner, M.4
Reyniers, J.A.5
-
3
-
-
4444250213
-
The production and use of germ-free animals in experimental biology and medicine
-
Reyniers JA. The production and use of germ-free animals in experimental biology and medicine. Am J Vet Res. 1957;18 (68):678-87.
-
(1957)
Am J Vet Res
, vol.18
, Issue.68
, pp. 678-687
-
-
Reyniers, J.A.1
-
4
-
-
37049246916
-
Germfree animals and biological research
-
Pollard M. Germfree animals and biological research. Science. 1964;145(3629):247-51.
-
(1964)
Science
, vol.145
, Issue.3629
, pp. 247-251
-
-
Pollard, M.1
-
5
-
-
79955618023
-
Impact of a probiotic Enterococcus faecalis in a gnotobiotic mouse model of experimental colitis
-
Hoffmann M, Messlik A, Kim SC, Sartor RB, Haller D. Impact of a probiotic Enterococcus faecalis in a gnotobiotic mouse model of experimental colitis. Mol Nutr Food Res. 2011;55(5):703-13.
-
(2011)
Mol Nutr Food Res
, vol.55
, Issue.5
, pp. 703-713
-
-
Hoffmann, M.1
Messlik, A.2
Kim, S.C.3
Sartor, R.B.4
Haller, D.5
-
6
-
-
33748039462
-
Symbiotic bacteria direct expression of an intestinal bactericidal lectin
-
DOI 10.1126/science.1127119
-
Cash HL, Whitham CV, Behrendt CL, Hooper LV. Symbiotic bacteria direct expression of an intestinal bactericidal lectin. Science. 2006;313(5790):1126- 30. (Pubitemid 44300239)
-
(2006)
Science
, vol.313
, Issue.5790
, pp. 1126-1130
-
-
Cash, H.L.1
Whitham, C.V.2
Behrendt, C.L.3
Hooper, L.V.4
-
7
-
-
80054122238
-
The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine
-
Oct 14
-
Vaishnava S, Yamamoto M, Severson KM, et al. The antibacterial lectin RegIIIgamma promotes the spatial segregation of microbiota and host in the intestine. Science. Oct 14 2011;334(6053):255-258.
-
(2011)
Science
, vol.334
, Issue.6053
, pp. 255-258
-
-
Vaishnava, S.1
Yamamoto, M.2
Severson, K.M.3
-
8
-
-
0035793372
-
Molecular analysis of commensal host-microbial relationships in the intestine
-
DOI 10.1126/science.291.5505.881
-
Hooper LV, Wong MH, Thelin A, Hansson L, Falk PG, Gordon JI. Molecular analysis of commensal host-microbial relationships in the intestine. Science. 2001;291(5505):881-4. (Pubitemid 32120760)
-
(2001)
Science
, vol.291
, Issue.5505
, pp. 881-884
-
-
Hooper, L.V.1
Wong, M.H.2
Thelin, A.3
Hansson, L.4
Falk, P.G.5
Gordon, J.I.6
-
9
-
-
0037470975
-
A genomic view of the human-Bacteroides thetaiotaomicron symbiosis
-
DOI 10.1126/science.1080029
-
Xu J, Bjursell MK, Himrod J, et al. A genomic view of the human- Bacteroides thetaiotaomicron symbiosis. Science. 2003;299 (5615):2074-6. (Pubitemid 36383735)
-
(2003)
Science
, vol.299
, Issue.5615
, pp. 2074-2076
-
-
Xu, J.1
Bjursell, M.K.2
Himrod, J.3
Deng, S.4
Carmichael, L.K.5
Chiang, H.C.6
Hooper, L.V.7
Gordon, J.I.8
-
10
-
-
22144490199
-
An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system
-
DOI 10.1016/j.cell.2005.05.007, PII S0092867405004514
-
Mazmanian SK, Liu CH, Tzianabos AO, Kasper DL. An immunomodulatory molecule of symbiotic bacteria directs maturation of the host immune system. Cell. 2005;122(1):107-18. (Pubitemid 40977944)
-
(2005)
Cell
, vol.122
, Issue.1
, pp. 107-118
-
-
Mazmanian, S.K.1
Cui, H.L.2
Tzianabos, A.O.3
Kasper, D.L.4
-
11
-
-
33748155285
-
Bacterial glycans: Key mediators of diverse host immune responses
-
DOI 10.1016/j.cell.2006.08.021, PII S0092867406010889
-
Comstock LE, Kasper DL. Bacterial glycans: key mediators of diverse host immune responses. Cell. 2006;126(5):847-50. (Pubitemid 44310786)
-
(2006)
Cell
, vol.126
, Issue.5
, pp. 847-850
-
-
Comstock, L.E.1
Kasper, D.L.2
-
12
-
-
77955655862
-
Microbiota-stimulated immunemechanisms to maintain gut homeostasis
-
ChungH,Kasper DL.Microbiota-stimulated immunemechanisms to maintain gut homeostasis. Curr Opin Immunol. 2010;22(4):455-60.
-
(2010)
Curr Opin Immunol
, vol.22
, Issue.4
, pp. 455-460
-
-
Chung, H.1
Kasper, D.L.2
-
14
-
-
35348857386
-
Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases
-
DOI 10.1073/pnas.0706625104
-
Frank DN, St Amand AL, Feldman RA, Boedeker EC, Harpaz N, Pace NR. Molecular-phylogenetic characterization of microbial community imbalances in human inflammatory bowel diseases. Proc Natl Acad Sci U S A. 2007;104(34):13780-5. (Pubitemid 350003397)
-
(2007)
Proceedings of the National Academy of Sciences of the United States of America
, vol.104
, Issue.34
, pp. 13780-13785
-
-
Frank, D.N.1
St. Amand, A.L.2
Feldman, R.A.3
Boedeker, E.C.4
Harpaz, N.5
Pace, N.R.6
-
15
-
-
70349488325
-
Low counts of Faecalibacterium prausnitzii in colitis microbiota
-
Sokol H, Seksik P, Furet JP, et al. Low counts of Faecalibacterium prausnitzii in colitis microbiota. Inflamm Bowel Dis. 2009;15 (8):1183-9.
-
(2009)
Inflamm Bowel Dis
, vol.15
, Issue.8
, pp. 1183-1189
-
-
Sokol, H.1
Seksik, P.2
Furet, J.P.3
-
16
-
-
79956078164
-
Commensal Bacteroides species induce colitis in host-genotype-specific fashion in a mouse model of inflammatory bowel disease
-
May 19
-
Bloom SM, Bijanki VN, Nava GM, et al. Commensal Bacteroides species induce colitis in host-genotype-specific fashion in a mouse model of inflammatory bowel disease. Cell Host Microbe. May 19 2011;9(5):390-403.
-
(2011)
Cell Host Microbe
, vol.9
, Issue.5
, pp. 390-403
-
-
Bloom, S.M.1
Bijanki, V.N.2
Nava, G.M.3
-
17
-
-
46749119859
-
Molecular analysis of the gut microbiota of identical twins with Crohn's disease
-
DOI 10.1038/ismej.2008.37, PII ISMEJ200837
-
Dicksved J, Halfvarson J, Rosenquist M, et al. Molecular analysis of the gut microbiota of identical twins with Crohn's disease. ISME J. 2008;2(7):716-27. (Pubitemid 351951567)
-
(2008)
ISME Journal
, vol.2
, Issue.7
, pp. 716-727
-
-
Dicksved, J.1
Halfvarson, J.2
Rosenquist, M.3
Jarnerot, G.4
Tysk, C.5
Apajalahti, J.6
Engstrand, L.7
Jansson, J.K.8
-
18
-
-
58749112734
-
A core gut microbiome in obese and lean twins
-
Jan 22
-
Turnbaugh PJ, Hamady M, Yatsunenko T, et al. A core gut microbiome in obese and lean twins. Nature. Jan 22 2009;457 (7228):480-484.
-
(2009)
Nature
, vol.457
, Issue.7228
, pp. 480-484
-
-
Turnbaugh, P.J.1
Hamady, M.2
Yatsunenko, T.3
-
19
-
-
0032412057
-
Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice
-
Sellon RK, Tonkonogy S, Schultz M, et al. Resident enteric bacteria are necessary for development of spontaneous colitis and immune system activation in interleukin-10-deficient mice. Infect Immun. 1998;66(11):5224-31. (Pubitemid 29044613)
-
(1998)
Infection and Immunity
, vol.66
, Issue.11
, pp. 5224-5231
-
-
Sellon, R.K.1
Tonkonogy, S.2
Schultz, M.3
Dieleman, L.A.4
Grenther, W.5
Balish, E.6
Rennick, D.M.7
Sartor, R.B.8
-
20
-
-
77956289824
-
Toll-like receptors in inflammatory bowel diseases: A decade later
-
Cario E. Toll-like receptors in inflammatory bowel diseases: a decade later. Inflamm Bowel Dis. 2010;16(9):1583-97.
-
(2010)
Inflamm Bowel Dis
, vol.16
, Issue.9
, pp. 1583-1597
-
-
Cario, E.1
-
21
-
-
33747114270
-
Role of toll-like receptors in spontaneous commensal-dependent colitis
-
DOI 10.1016/j.immuni.2006.06.010, PII S107476130600344X
-
Rakoff-Nahoum S, Hao L, Medzhitov R. Role of toll-like receptors in spontaneous commensal-dependent colitis. Immunity. 2006;25 (2):319-29. (Pubitemid 44224143)
-
(2006)
Immunity
, vol.25
, Issue.2
, pp. 319-329
-
-
Rakoff-Nahoum, S.1
Hao, L.2
Medzhitov, R.3
-
22
-
-
84861096964
-
Interleukin-1{beta} (IL-1{beta}) promotes susceptibility of Tolllike receptor 5 (TLR5) deficient mice to colitis
-
Jun 5
-
Carvalho FA, Nalbantoglu I, Ortega-Fernandez S, et al. Interleukin-1{beta} (IL-1{beta}) promotes susceptibility of Tolllike receptor 5 (TLR5) deficient mice to colitis. Gut. Jun 5 2011.
-
(2011)
Gut
-
-
Carvalho, F.A.1
Nalbantoglu, I.2
Ortega-Fernandez, S.3
-
23
-
-
70349427086
-
Toll-like receptor 4- mediated regulation of spontaneous Helicobacter-dependent colitis in IL-10-deficient mice
-
Matharu KS, Mizoguchi E, Cotoner CA, et al. Toll-like receptor 4- mediated regulation of spontaneous Helicobacter-dependent colitis in IL-10-deficient mice. Gastroenterology. 2009;137(4):1380-1390-e1381-1383.
-
(2009)
Gastroenterology
, vol.137
, Issue.4
-
-
Matharu, K.S.1
Mizoguchi, E.2
Cotoner, C.A.3
-
24
-
-
14644403009
-
Toll-like receptor 9-induced type I IFN protects mice from experimental colitis
-
DOI 10.1172/JCI200522996
-
Katakura K, Lee J, Rachmilewitz D, Li G, Eckmann L, Raz E. Toll-like receptor 9-induced type I IFN protects mice from experimental colitis. J Clin Invest. 2005;115(3):695-702. (Pubitemid 40322244)
-
(2005)
Journal of Clinical Investigation
, vol.115
, Issue.3
, pp. 695-702
-
-
Katakura, K.1
Lee, J.2
Rachmilewitz, D.3
Li, G.4
Eckmann, L.5
Raz, E.6
-
25
-
-
3242664636
-
Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis
-
DOI 10.1016/j.cell.2004.07.002, PII S0092867404006610
-
Rakoff-Nahoum S, Paglino J, Eslami-Varzaneh F, Edberg S, Medzhitov R. Recognition of commensal microflora by toll-like receptors is required for intestinal homeostasis. Cell. 2004;118(2):229-41. (Pubitemid 38962578)
-
(2004)
Cell
, vol.118
, Issue.2
, pp. 229-241
-
-
Rakoff-Nahoum, S.1
Paglino, J.2
Eslami-Varzaneh, F.3
Edberg, S.4
Medzhitov, R.5
-
26
-
-
0038109983
-
Crohn's disease and the NOD2 gene: A role for paneth cells
-
DOI 10.1016/S0016-5085(03)00661-9
-
Lala S, Ogura Y, Osborne C, et al. Crohn's disease and the NOD2 gene: a role for paneth cells. Gastroenterology. 2003;125(1):47-57. (Pubitemid 36799106)
-
(2003)
Gastroenterology
, vol.125
, Issue.1
, pp. 47-57
-
-
Lala, S.1
Ogura, Y.2
Osborne, C.3
Hor, S.Y.4
Bromfield, A.5
Davies, S.6
Ogunbiyi, O.7
Nunez, G.8
Keshav, S.9
-
27
-
-
7244257312
-
NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal α-defensin expression
-
DOI 10.1136/gut.2003.032805
-
Wehkamp J, Harder J, Weichenthal M, et al. NOD2 (CARD15) mutations in Crohn's disease are associated with diminished mucosal alpha-defensin expression. Gut. 2004;53(11):1658-64. (Pubitemid 39434112)
-
(2004)
Gut
, vol.53
, Issue.11
, pp. 1658-1664
-
-
Wehkamp, J.1
Harder, J.2
Weichenthal, M.3
Schwab, M.4
Schaffeler, E.5
Schlee, M.6
Herrlinger, K.R.7
Stallmach, A.8
Noack, F.9
Fritz, P.10
Schroder, J.M.11
Bevins, C.L.12
Fellermann, K.13
Stange, E.F.14
-
28
-
-
56249135538
-
A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells
-
Cadwell K, Liu JY, Brown SL, et al. A key role for autophagy and the autophagy gene Atg16l1 in mouse and human intestinal Paneth cells. Nature. 2008;456(7219):259-63.
-
(2008)
Nature
, vol.456
, Issue.7219
, pp. 259-263
-
-
Cadwell, K.1
Liu, J.Y.2
Brown, S.L.3
-
29
-
-
20244364236
-
Wnt signalling induces maturation of Paneth cells in intestinal crypts
-
DOI 10.1038/ncb1240
-
van Es JH, Jay P, Gregorieff A, et al. Wnt signalling induces maturation of Paneth cells in intestinal crypts. Nat Cell Biol. 2005;7(4):381-6. (Pubitemid 40533127)
-
(2005)
Nature Cell Biology
, vol.7
, Issue.4
, pp. 381-386
-
-
Van Es, J.H.1
Jay, P.2
Gregorieff, A.3
Van Gijn, M.E.4
Jonkheer, S.5
Hatzis, P.6
Thiele, A.7
Van Den Born, M.8
Begthel, H.9
Brabletz, T.10
Taketo, M.M.11
Clevers, H.12
-
30
-
-
34547956892
-
Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium
-
DOI 10.1083/jcb.200704152
-
Bastide P, Darido C, Pannequin J, et al. Sox9 regulates cell proliferation and is required for Paneth cell differentiation in the intestinal epithelium. J Cell Biol. 2007;178(4):635-48. (Pubitemid 47267275)
-
(2007)
Journal of Cell Biology
, vol.178
, Issue.4
, pp. 635-648
-
-
Bastide, P.1
Darido, C.2
Pannequin, J.3
Kist, R.4
Robine, S.5
Marty-Double, C.6
Bibeau, F.7
Scherer, G.8
Joubert, D.9
Hollande, F.10
Blache, P.11
Jay, P.12
-
31
-
-
18644376279
-
β-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/EphrinB
-
DOI 10.1016/S0092-8674(02)01015-2
-
Batlle E, Henderson JT, Beghtel H, et al. Beta-catenin and TCF mediate cell positioning in the intestinal epithelium by controlling the expression of EphB/ephrinB. Cell. 2002;111(2):251-63. (Pubitemid 35292445)
-
(2002)
Cell
, vol.111
, Issue.2
, pp. 251-263
-
-
Batlle, E.1
Henderson, J.T.2
Beghtel, H.3
Van Den Born, M.M.W.4
Sancho, E.5
Huls, G.6
Meeldijk, J.7
Robertson, J.8
Van De Wetering, M.9
Pawson, T.10
Clevers, H.11
-
32
-
-
37349070287
-
The Paneth cell alphadefensin deficiency of ileal Crohn's disease is linked to Wnt/Tcf- 4
-
Wehkamp J, Wang G, Kubler I, et al. The Paneth cell alphadefensin deficiency of ileal Crohn's disease is linked to Wnt/Tcf- 4. J Immunol. 2007;179(5):3109-18.
-
(2007)
J Immunol
, vol.179
, Issue.5
, pp. 3109-3118
-
-
Wehkamp, J.1
Wang, G.2
Kubler, I.3
-
33
-
-
10744222688
-
Expression of NOD2 in Paneth cells: A possible link to Crohn's ileitis
-
DOI 10.1136/gut.52.11.1591
-
Ogura Y, Lala S, XinW, et al. Expression of NOD2 in Paneth cells: a possible link to Crohn's ileitis. Gut. 2003;52(11):1591-7. (Pubitemid 37363443)
-
(2003)
Gut
, vol.52
, Issue.11
, pp. 1591-1597
-
-
Ogura, Y.1
Lala, S.2
Xin, W.3
Smith, E.4
Dowds, T.A.5
Chen, F.F.6
Zimmermann, E.7
Tretiakova, M.8
Cho, J.H.9
Hart, J.10
Greenson, J.K.11
Keshav, S.12
Nunez, G.13
-
34
-
-
58049200723
-
Function of Nod-like receptors in microbial recognition and host defense
-
Franchi L, Warner N, Viani K, Nunez G. Function of Nod-like receptors in microbial recognition and host defense. Immunol Rev. 2009;227(1):106-28.
-
(2009)
Immunol Rev
, vol.227
, Issue.1
, pp. 106-128
-
-
Franchi, L.1
Warner, N.2
Viani, K.3
Nunez, G.4
-
35
-
-
19744366535
-
Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease
-
DOI 10.1093/hmg/ddi135
-
McGovern DP, Hysi P, Ahmad T, et al. Association between a complex insertion/deletion polymorphism in NOD1 (CARD4) and susceptibility to inflammatory bowel disease. Hum Mol Genet. 2005;14(10):1245-50. (Pubitemid 40744484)
-
(2005)
Human Molecular Genetics
, vol.14
, Issue.10
, pp. 1245-1250
-
-
McGovern, D.P.B.1
Hysi, P.2
Ahmad, T.3
Van Heel, D.A.4
Moffatt, M.F.5
Carey, A.6
Cookson, W.O.C.7
Jewell, D.P.8
-
36
-
-
0035978533
-
A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease
-
DOI 10.1038/35079114
-
Ogura Y, Bonen DK, Inohara N, et al. A frameshift mutation in NOD2 associated with susceptibility to Crohn's disease. Nature. 2001;411(6837):603-6. (Pubitemid 32531409)
-
(2001)
Nature
, vol.411
, Issue.6837
, pp. 603-606
-
-
Ogura, Y.1
Bonen, D.K.2
Inohara, N.3
Nicolae, D.L.4
Chen, F.F.5
Ramos, R.6
Britton, H.7
Moran, T.8
Karaliuskas, R.9
Duerr, R.H.10
Achkar, J.-P.11
Brant, S.R.12
Bayless, T.M.13
Kirschner, B.S.14
Hanauer, S.B.15
Nuez, G.16
Cho, J.H.17
-
37
-
-
0035978651
-
Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease
-
DOI 10.1038/35079107
-
Hugot JP, Chamaillard M, Zouali H, et al. Association of NOD2 leucine-rich repeat variants with susceptibility to Crohn's disease. Nature. 2001;411(6837):599-603. (Pubitemid 32531408)
-
(2001)
Nature
, vol.411
, Issue.6837
, pp. 599-603
-
-
Hugot, J.-P.1
Chamaillard, M.2
Zouali, H.3
Lesage, S.4
Cezard, J.-P.5
Belaiche, J.6
Almer, S.7
Tysk, C.8
O'morain, C.A.9
Gassull, M.10
Binder, V.11
Finkel, Y.12
Cortot, A.13
Modigliani, R.14
Laurent-Puig, P.15
Gower-Rousseau, C.16
Macry, J.17
Colombel, J.-F.18
Sahbatou, M.19
Thomas, G.20
more..
-
38
-
-
0037075551
-
RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems
-
DOI 10.1038/416194a
-
Kobayashi K, Inohara N, Hernandez LD, et al. RICK/Rip2/CARDIAK mediates signalling for receptors of the innate and adaptive immune systems. Nature. 2002;416(6877):194-9. (Pubitemid 34246479)
-
(2002)
Nature
, vol.416
, Issue.6877
, pp. 194-199
-
-
Kobayashi, K.1
Inohara, N.2
Hernandez, L.D.3
Galan, J.E.4
Nunez, G.5
Janeway, C.A.6
Medzhitov, R.7
Flavell, R.A.8
-
39
-
-
0037075549
-
Involvement of receptor-interacting protein 2 in innate and adaptive immune responses
-
DOI 10.1038/416190a
-
Chin AI, Dempsey PW, Bruhn K, Miller JF, Xu Y, Cheng G. Involvement of receptor-interacting protein 2 in innate and adaptive immune responses. Nature. 2002;416(6877):190-4. (Pubitemid 34246478)
-
(2002)
Nature
, vol.416
, Issue.6877
, pp. 190-194
-
-
Chin, A.I.1
Dempsey, P.W.2
Bruhn, K.3
Miller, J.F.4
Xu, Y.5
Cheng, G.6
-
40
-
-
56749146467
-
Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis
-
DOI 10.1038/nature07450, PII NATURE07450
-
Bouskra D, Brezillon C, Berard M, et al. Lymphoid tissue genesis induced by commensals through NOD1 regulates intestinal homeostasis. Nature. 2008;456(7221):507-10. (Pubitemid 352759006)
-
(2008)
Nature
, vol.456
, Issue.7221
, pp. 507-510
-
-
Bouskra, D.1
Brezillon, C.2
Berard, M.3
Werts, C.4
Varona, R.5
Boneca, I.G.6
Eberl, G.7
-
41
-
-
76249120134
-
Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity
-
Feb
-
Clarke TB, Davis KM, Lysenko ES, Zhou AY, Yu Y, Weiser JN. Recognition of peptidoglycan from the microbiota by Nod1 enhances systemic innate immunity. Nat Med. Feb 2010;16(2):228-231.
-
(2010)
Nat Med
, vol.16
, Issue.2
, pp. 228-231
-
-
Clarke, T.B.1
Davis, K.M.2
Lysenko, E.S.3
Zhou, A.Y.4
Yu, Y.5
Weiser, J.N.6
-
42
-
-
31944437924
-
Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo
-
Masumoto J, Yang K, Varambally S, et al. Nod1 acts as an intracellular receptor to stimulate chemokine production and neutrophil recruitment in vivo. J Exp Med. 2006;203(1):203-13.
-
(2006)
J Exp Med
, vol.203
, Issue.1
, pp. 203-213
-
-
Masumoto, J.1
Yang, K.2
Varambally, S.3
-
43
-
-
9244245293
-
Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island
-
DOI 10.1038/ni1131
-
Viala J, Chaput C, Boneca IG, et al. Nod1 responds to peptidoglycan delivered by the Helicobacter pylori cag pathogenicity island. Nat Immunol. 2004;5(11):1166-74. (Pubitemid 39549631)
-
(2004)
Nature Immunology
, vol.5
, Issue.11
, pp. 1166-1174
-
-
Viala, J.1
Chaput, C.2
Boneca, I.G.3
Cardona, A.4
Girardin, S.E.5
Moran, A.P.6
Athman, R.7
Memet, S.8
Huerre, M.R.9
Coyle, A.J.10
DiStefano, P.S.11
Sansonetti, P.J.12
Labigne, A.13
Bertin, J.14
Philpott, D.J.15
Ferrero, R.L.16
-
44
-
-
13244292161
-
Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract
-
DOI 10.1126/science.1104911
-
Kobayashi KS, Chamaillard M, Ogura Y, et al. Nod2-dependent regulation of innate and adaptive immunity in the intestinal tract. Science. 2005;307(5710):731-4. (Pubitemid 40194644)
-
(2005)
Science
, vol.307
, Issue.5710
, pp. 731-734
-
-
Kobayashi, K.S.1
Chamaillard, M.2
Ogura, Y.3
Henegariu, O.4
Inohara, N.5
Nunez, G.6
Flavell, R.A.7
-
45
-
-
13244277880
-
Nod2 mutation in Crohn's disease potentiates NF-κB activity and IL-1β processing
-
DOI 10.1126/science.1103685
-
Maeda S, Hsu LC, Liu H, et al. Nod2 mutation in Crohn's disease potentiates NF-kappaB activity and IL-1beta processing. Science. 2005;307(5710):734-8. (Pubitemid 40194645)
-
(2005)
Science
, vol.307
, Issue.5710
, pp. 734-738
-
-
Maeda, S.1
Hsu, L.-C.2
Liu, H.3
Bankston, L.A.4
Iimura, M.5
Kagnoff, M.F.6
Eckmann, L.7
Karin, M.8
-
46
-
-
34848928674
-
CARD15/NOD2 is required for Peyer's patches homeostasis in mice
-
Barreau F, Meinzer U, Chareyre F, et al. CARD15/NOD2 is required for Peyer's patches homeostasis in mice. PLoS One. 2007;2(6):e523.
-
(2007)
PLoS One
, vol.2
, Issue.6
-
-
Barreau, F.1
Meinzer, U.2
Chareyre, F.3
-
47
-
-
82255173966
-
The unfolded protein response: From stress pathway to homeostatic regulation
-
Walter P, Ron D. The unfolded protein response: from stress pathway to homeostatic regulation. Science. 2011;334 (6059):1081-6.
-
(2011)
Science
, vol.334
, Issue.6059
, pp. 1081-1086
-
-
Walter, P.1
Ron, D.2
-
48
-
-
50249086073
-
XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease
-
Kaser A, Lee AH, Franke A, et al. XBP1 links ER stress to intestinal inflammation and confers genetic risk for human inflammatory bowel disease. Cell. 2008;134(5):743-56.
-
(2008)
Cell
, vol.134
, Issue.5
, pp. 743-756
-
-
Kaser, A.1
Lee, A.H.2
Franke, A.3
-
49
-
-
84864974347
-
Induction of dsRNA-activated protein kinase links mitochondrial unfolded protein response to the pathogenesis of intestinal inflammation
-
Oct 13
-
Rath E, Berger E, Messlik A, et al. Induction of dsRNA-activated protein kinase links mitochondrial unfolded protein response to the pathogenesis of intestinal inflammation. Gut. Oct 13 2011.
-
(2011)
Gut
-
-
Rath, E.1
Berger, E.2
Messlik, A.3
-
50
-
-
33846627302
-
A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1
-
DOI 10.1038/ng1954, PII NG1954
-
Hampe J, Franke A, Rosenstiel P, et al. A genome-wide association scan of nonsynonymous SNPs identifies a susceptibility variant for Crohn disease in ATG16L1. Nat Genet. 2007;39(2):207-11. (Pubitemid 46184351)
-
(2007)
Nature Genetics
, vol.39
, Issue.2
, pp. 207-211
-
-
Hampe, J.1
Franke, A.2
Rosenstiel, P.3
Till, A.4
Teuber, M.5
Huse, K.6
Albrecht, M.7
Mayr, G.8
De La Vega, F.M.9
Briggs, J.10
Gunther, S.11
Prescott, N.J.12
Onnie, C.M.13
Hasler, R.14
Sipos, B.15
Folsch, U.R.16
Lengauer, T.17
Platzer, M.18
Mathew, C.G.19
Krawczak, M.20
Schreiber, S.21
more..
-
51
-
-
34548700796
-
Unveiling the roles of autophagy in innate and adaptive immunity
-
DOI 10.1038/nri2161, PII NRI2161
-
Levine B, Deretic V. Unveiling the roles of autophagy in innate and adaptive immunity. Nat Rev Immunol. 2007;7(10):767-77. (Pubitemid 47480305)
-
(2007)
Nature Reviews Immunology
, vol.7
, Issue.10
, pp. 767-777
-
-
Levine, B.1
Deretic, V.2
-
52
-
-
27944504351
-
P62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death
-
DOI 10.1083/jcb.200507002
-
Bjorkoy G, Lamark T, Brech A, et al. p62/SQSTM1 forms protein aggregates degraded by autophagy and has a protective effect on huntingtin-induced cell death. J Cell Biol. 2005;171(4):603-14. (Pubitemid 41668720)
-
(2005)
Journal of Cell Biology
, vol.171
, Issue.4
, pp. 603-614
-
-
Bjorkoy, G.1
Lamark, T.2
Brech, A.3
Outzen, H.4
Perander, M.5
Overvatn, A.6
Stenmark, H.7
Johansen, T.8
-
53
-
-
70350450808
-
The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria
-
Thurston TL, Ryzhakov G, Bloor S, von Muhlinen N, Randow F. The TBK1 adaptor and autophagy receptor NDP52 restricts the proliferation of ubiquitin-coated bacteria. Nat Immunol. 2009;10 (11):1215-21.
-
(2009)
Nat Immunol
, vol.10
, Issue.11
, pp. 1215-1221
-
-
Thurston, T.L.1
Ryzhakov, G.2
Bloor, S.3
Von Muhlinen, N.4
Randow, F.5
-
54
-
-
56249090667
-
Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production
-
Saitoh T, Fujita N, Jang MH, et al. Loss of the autophagy protein Atg16L1 enhances endotoxin-induced IL-1beta production. Nature. 2008;456(7219):264-8.
-
(2008)
Nature
, vol.456
, Issue.7219
, pp. 264-268
-
-
Saitoh, T.1
Fujita, N.2
Jang, M.H.3
-
55
-
-
77953904042
-
Virus-plussusceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine
-
Jun 25
-
Cadwell K, Patel KK, Maloney NS, et al. Virus-plussusceptibility gene interaction determines Crohn's disease gene Atg16L1 phenotypes in intestine. Cell. Jun 25 2010;141 (7):1135-1145.
-
(2010)
Cell
, vol.141
, Issue.7
, pp. 1135-1145
-
-
Cadwell, K.1
Patel, K.K.2
Maloney, N.S.3
-
56
-
-
73849121209
-
Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry
-
Jan
-
Travassos LH, Carneiro LA, Ramjeet M, et al. Nod1 and Nod2 direct autophagy by recruiting ATG16L1 to the plasma membrane at the site of bacterial entry. Nat Immunol. Jan 2010;11(1):55-62.
-
(2010)
Nat Immunol
, vol.11
, Issue.1
, pp. 55-62
-
-
Travassos, L.H.1
Carneiro, L.A.2
Ramjeet, M.3
-
57
-
-
73849151394
-
NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation
-
Cooney R, Baker J, Brain O, et al. NOD2 stimulation induces autophagy in dendritic cells influencing bacterial handling and antigen presentation. Nat Med. 2010;16(1):90-7.
-
(2010)
Nat Med
, vol.16
, Issue.1
, pp. 90-97
-
-
Cooney, R.1
Baker, J.2
Brain, O.3
-
58
-
-
77957682295
-
ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis
-
1641 e1631-1632
-
Homer CR, Richmond AL, Rebert NA, Achkar JP, McDonald C. ATG16L1 and NOD2 interact in an autophagy-dependent antibacterial pathway implicated in Crohn's disease pathogenesis. Gastroenterology. 2010;139(5):1630-41. 1641 e1631-1632.
-
(2010)
Gastroenterology
, vol.139
, Issue.5
, pp. 1630-1641
-
-
Homer, C.R.1
Richmond, A.L.2
Rebert, N.A.3
Achkar, J.P.4
McDonald, C.5
-
59
-
-
54849421128
-
Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant
-
Kuballa P, Huett A, Rioux JD, Daly MJ, Xavier RJ. Impaired autophagy of an intracellular pathogen induced by a Crohn's disease associated ATG16L1 variant. PLoS One. 2008;3(10): e3391.
-
(2008)
PLoS One
, vol.3
, Issue.10
-
-
Kuballa, P.1
Huett, A.2
Rioux, J.D.3
Daly, M.J.4
Xavier, R.J.5
-
60
-
-
34347338690
-
Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility
-
DOI 10.1038/ng2061, PII NG2061
-
Parkes M, Barrett JC, Prescott NJ, et al. Sequence variants in the autophagy gene IRGM and multiple other replicating loci contribute to Crohn's disease susceptibility. Nat Genet. 2007;39(7):830-2. (Pubitemid 47014496)
-
(2007)
Nature Genetics
, vol.39
, Issue.7
, pp. 830-832
-
-
Parkes, M.1
Barrett, J.C.2
Prescott, N.J.3
Tremelling, M.4
Anderson, C.A.5
Fisher, S.A.6
Roberts, R.G.7
Nimmo, E.R.8
Cummings, F.R.9
Soars, D.10
Drummond, H.11
Lees, C.W.12
Khawaja, S.A.13
Bagnall, R.14
Burke, D.A.15
Todhunter, C.E.16
Ahmad, T.17
Onnie, C.M.18
McArdle, W.19
Strachan, D.20
Bethel, G.21
Bryan, C.22
Lewis, C.M.23
Deloukas, P.24
Forbes, A.25
Sanderson, J.26
Jewell, D.P.27
Satsangi, J.28
Mansfield, J.C.29
Cardon, L.30
Mathew, C.G.31
more..
-
61
-
-
50449091647
-
Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease
-
McCarroll SA, Huett A, Kuballa P, et al. Deletion polymorphism upstream of IRGM associated with altered IRGM expression and Crohn's disease. Nat Genet. 2008;40(9):1107-12.
-
(2008)
Nat Genet
, vol.40
, Issue.9
, pp. 1107-1112
-
-
McCarroll, S.A.1
Huett, A.2
Kuballa, P.3
-
62
-
-
33748506089
-
Human IRGM induces autophagy to eliminate intracellular mycobacteria
-
DOI 10.1126/science.1129577
-
Singh SB, Davis AS, Taylor GA, Deretic V. Human IRGM induces autophagy to eliminate intracellular mycobacteria. Science. 2006;313(5792):1438-41. (Pubitemid 44360272)
-
(2006)
Science
, vol.313
, Issue.5792
, pp. 1438-1441
-
-
Singh, S.B.1
Davis, A.S.2
Taylor, G.A.3
Deretic, V.4
-
63
-
-
79952134938
-
A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease
-
Mar
-
Brest P, Lapaquette P, Souidi M, et al. A synonymous variant in IRGM alters a binding site for miR-196 and causes deregulation of IRGM-dependent xenophagy in Crohn's disease. Nat Genet. Mar 2011;43(3):242-245.
-
(2011)
Nat Genet
, vol.43
, Issue.3
, pp. 242-245
-
-
Brest, P.1
Lapaquette, P.2
Souidi, M.3
|