A genomic view of the human-Bacteroides thetaiotaomicron symbiosis

Science

Volumn 299, Issue 5615, 2003, Pages 2074-2076

  Xu, Jian ^a   Bjursell, Magnus K ^a   Himrod, Jason ^a   Deng, Su ^a   Carmichael, Lynn K ^a   Chiang, Herbert C ^a   Hooper, Lora V ^a   Gordon, Jeffrey I ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BIOLOGY; MICROORGANISMS; POLYSACCHARIDES;

INTESTINAL MICROBIOTA;

GENES;

POLYSACCHARIDE; PROTEOME;

BACTERIUM; GENOME;

ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GENE; BACTEROIDES THETAIOTAOMICRON; GENE SEQUENCE; HOST PATHOGEN INTERACTION; HUMAN; HYDROLYSIS; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SYMBIOSIS;

ADULT; BACTERIAL OUTER MEMBRANE PROTEINS; BACTERIAL PROTEINS; BACTEROIDES; CARBOHYDRATE METABOLISM; CHROMOSOMES, BACTERIAL; EVOLUTION; GENE EXPRESSION REGULATION, BACTERIAL; GENES, BACTERIAL; GENOME, BACTERIAL; HUMANS; INTERSPERSED REPETITIVE SEQUENCES; INTESTINES; PHYSICAL CHROMOSOME MAPPING; POLYSACCHARIDES; PROTEOME; SEQUENCE ANALYSIS, DNA; SIGMA FACTOR; SIGNAL TRANSDUCTION; SYMBIOSIS;

BACTERIA (MICROORGANISMS); BACTEROIDES THETAIOTAOMICRON; MICROBIOTA; NEGIBACTERIA; PROKARYOTA;

EID: 0037470975     PISSN: 00368075     EISSN: None     Source Type: Journal    
DOI: 10.1126/science.1080029     Document Type: Article

References (21)

1. D. C. Savage, Annu. Rev. Microbiol. 31, 107 (1977).
2. L. V. Hooper, J. J. Gordon, Science 292, 1115 (2001).
3. L. V. Hooper, T. Midtvedt, J. J. Gordon, Annu. Rev. Nutr. 22, 282 (2002).
4. C. Braun-Fahrlander et al., N. Engl. J. Med. 347, 869 (2002).
5. L. V. Hooper et al., Science 291, 881 (2001).
6. L. V. Hooper, T. S. Stappenbeck, C. V. Hong, J. I. Gordon, Nature Immunol. 4, 269 (2003).
7. T. S. Stappenbeck, L. V. Hooper, J. I. Gordon, Proc. Natl. Acad. Sci. U.S.A. 99, 15451 (2002).
8. W. E. Moore, L. V. Holdeman, Appl. Microbiol. 27, 961 (1974).
9. L. V. Hooper, J. Xu, P. G. Falk, T. Midtvedt, J. I. Gordon, Proc. Natl. Acad. Sci. U.S.A. 96, 9833 (1999).
10. A. A. Salyers, P. Valentine, V. Hwa, in Genetics and Molecular Biology of Anaerobic Bacteria, M. Sebald, Ed. (Springer-Verlag, New York, 1993), pp. 505-516.
11. E. N. Bergman, Physiol. Rev. 70, 567 (1990).
12. C. M. Krinos et al., Nature 414, 555 (2001).
13. A. Bateman et al., Nucleic Acids Res. 30, 276 (2002).
14. J. N. D'Elia, A. A. Salyers, J. Bacteriol. 178, 7180 (1997).
15. A. R. Reeves, G. R. Wang, A. A. Salyers, J. Bacteriol. 179, 643 (1997).
16. K. H. Cho, A. A. Salyers, J. Bacteriol. 183, 7224 (2001).
17. M. M. Wosten, FEMS Microbiol. Rev. 22, 127 (1998).
18. J. D. Helmann, Adv. Microb. Physiol. 46, 47 (2002).
19. G. Whittle, N. B. Shoemaker, A. A. Salyers, J. Bacteriol 184, 3839 (2002).
20. N. B. Shoemaker, H. Vlamakis, K. Hayes, A. A. Salyers, Appl. Environ. Microbiol. 67, 561 (2001).
21. We thank C. Baublite, C. Foushee, S. LaBrie, and D. Smoller, for assistance with BAC library construction and fingerprinting; A. Salyers and N. Shoemaker for providing p5482; P. Minx, H. Du, S.-p. Yang, J. Spieth, and J. Buhler for helpful discussions; C. Rexer for assistance with PCR; and P. Falk for continued support. This work was funded by AstraZeneca and the NIH (DK30292).