Identification of a highly conserved valine-glycine-phenylalanine amino acid triplet required for HIV-1 Nef function

Retrovirology

Volumn 9, Issue , 2012, Pages

  Meuwissen, Pieter J ^a   Stolp, Bettina ^b   Iannucci, Veronica ^a   Vermeire, Jolien ^a   Naessens, Evelien ^a   Saksela, Kalle ^c   Geyer, Matthias ^d   Vanham, Guido ^e   Arien, Kevin K ^a,e   Fackler, Oliver T ^b   Verhasselt, Bruno ^a  

^a GHENT UNIVERSITY   (Belgium)

^b UNIVERSITY HOSPITAL HEIDELBERG   (Germany)

^c HELSINKI UNIVERSITY CENTRAL HOSPITAL   (Finland)

^d MAX PLANCK INSTITUTE OF MOLECULAR PHYSIOLOGY   (Germany)

^e INSTITUTE OF TROPICAL MEDICINE   (Belgium)

Author keywords

Cytoskeleton; HIV; Infectivity; Lck; Nef; Receptor downregulation; Replication; Sequence motifs; SH3 domain binding

Indexed keywords

ACTIN; ALANINE; CELL PROTEIN; CHEMOKINE RECEPTOR CXCR4; COFILIN; MAJOR HISTOCOMPATIBILITY ANTIGEN CLASS 1; NEF PROTEIN; P21 ACTIVATED KINASE 2; PHENYLALANINE; PROTEIN KINASE LCK;

ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; CONSENSUS SEQUENCE; DISEASE COURSE; DOWN REGULATION; DRUG TARGETING; HOST CELL; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; NUCLEOTIDE SEQUENCE; PERIPHERAL LYMPHOCYTE; PROLINE RICH MOTIF; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; TRANS GOLGI NETWORK; VALINE GLYCINE PHENYLALANINE MOTIF; VIRION; VIRUS INFECTIVITY; VIRUS ISOLATION; VIRUS MUTANT; VIRUS REPLICATION;

ACTIN CYTOSKELETON; ALLELES; AMINO ACID MOTIFS; AMINO ACID SEQUENCE; CONSERVED SEQUENCE; GENES, MHC CLASS I; GLYCINE; HELA CELLS; HIV INFECTIONS; HIV-1; HOST-PATHOGEN INTERACTIONS; HUMANS; JURKAT CELLS; LYMPHOCYTES; NEF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; P21-ACTIVATED KINASES; PHENYLALANINE; PROTO-ONCOGENE PROTEINS C-HCK; RECEPTORS, CXCR4; SEQUENCE DELETION; SIGNAL TRANSDUCTION; STRUCTURE-ACTIVITY RELATIONSHIP; TRANS-GOLGI NETWORK; VALINE; VIRUS REPLICATION;

HUMAN IMMUNODEFICIENCY VIRUS 1;

EID: 84860201476     PISSN: None     EISSN: 17424690     Source Type: Journal    
DOI: 10.1186/1742-4690-9-34     Document Type: Article

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