-
1
-
-
0029924038
-
Mutational analysis of HIV-1 Nef: Identification of two mutants that are temperature-sensitive for CD4 downregulation
-
Aiken, C., L. Krause, Y. L. Chen, and D. Trono. 1996. Mutational analysis of HIV-1 Nef: identification of two mutants that are temperature-sensitive for CD4 downregulation. Virology 217:293-300.
-
(1996)
Virology
, vol.217
, pp. 293-300
-
-
Aiken, C.1
Krause, L.2
Chen, Y.L.3
Trono, D.4
-
2
-
-
0034001233
-
Nef-induced major histocompatibility complex class I down-regulation is functionally dissociated from its virion incorporation, enhancement of viral infectivity, and CD4 down-regulation
-
Akari, H., S. Arold, T. Fukumori, T. Okazaki, K. Strebel, and A. Adachi. 2000. Nef-induced major histocompatibility complex class I down-regulation is functionally dissociated from its virion incorporation, enhancement of viral infectivity, and CD4 down-regulation. J. Virol. 74:2907-2912.
-
(2000)
J. Virol.
, vol.74
, pp. 2907-2912
-
-
Akari, H.1
Arold, S.2
Fukumori, T.3
Okazaki, T.4
Strebel, K.5
Adachi, A.6
-
3
-
-
0030801002
-
Gapped BLAST and PSI-BLAST: A new generation of protein database search programs
-
Altschul, S. F., T. L. Madden, A. A. Schaffer, J. Zhang, Z. Zhang, W. Miller, and D. J. Lipman. 1997. Gapped BLAST and PSI-BLAST: a new generation of protein database search programs. Nucleic Acids Res. 25:3389-3402.
-
(1997)
Nucleic Acids Res.
, vol.25
, pp. 3389-3402
-
-
Altschul, S.F.1
Madden, T.L.2
Schaffer, A.A.3
Zhang, J.4
Zhang, Z.5
Miller, W.6
Lipman, D.J.7
-
4
-
-
0033917035
-
Characterization and molecular basis of the oligomeric structure of HIV-1 nef protein
-
Arold, S., F. Hoh, S. Domergue, C. Birck, M. A. Delsuc, M. Jullien, and C. Dumas. 2000. Characterization and molecular basis of the oligomeric structure of HIV-1 nef protein. Protein Sci. 9:1137-1148.
-
(2000)
Protein Sci.
, vol.9
, pp. 1137-1148
-
-
Arold, S.1
Hoh, F.2
Domergue, S.3
Birck, C.4
Delsuc, M.A.5
Jullien, M.6
Dumas, C.7
-
5
-
-
0035368515
-
Dynamic Nef and Nef dynamics: How structure could explain the complex activities of this small HIV protein
-
Arold, S. T., and A. S. Baur. 2001. Dynamic Nef and Nef dynamics: how structure could explain the complex activities of this small HIV protein. Trends Biochem. Sci. 26:356-363.
-
(2001)
Trends Biochem. Sci.
, vol.26
, pp. 356-363
-
-
Arold, S.T.1
Baur, A.S.2
-
7
-
-
0034469146
-
Lentivirus Nef specifically activates Pak2
-
Arora, V. K., R. P. Molina, J. L. Foster, J. L. Blakemore, J. Chernoff, B. L. Fredericksen, and J. V. Garcia. 2000. Lentivirus Nef specifically activates Pak2. J. Virol. 74:11081-11087.
-
(2000)
J. Virol.
, vol.74
, pp. 11081-11087
-
-
Arora, V.K.1
Molina, R.P.2
Foster, J.L.3
Blakemore, J.L.4
Chernoff, J.5
Fredericksen, B.L.6
Garcia, J.V.7
-
8
-
-
0030887932
-
The N-terminus of Nef from HIV-1/SIV associates with a protein complex containing Lck and a serine kinase
-
Baur, A. S., G. Sass, B. Laffert, D. Willbold, C. Cheng-Mayer, and B. M. Peterlin. 1997. The N-terminus of Nef from HIV-1/SIV associates with a protein complex containing Lck and a serine kinase. Immunity 6:283-291.
-
(1997)
Immunity
, vol.6
, pp. 283-291
-
-
Baur, A.S.1
Sass, G.2
Laffert, B.3
Willbold, D.4
Cheng-Mayer, C.5
Peterlin, B.M.6
-
9
-
-
0037074008
-
HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway
-
Blagoveshchenskaya, A. D., L. Thomas, S. F. Feliciangeli, C. H. Hung, and G. Thomas. 2002. HIV-1 Nef downregulates MHC-I by a PACS-1- and PI3K-regulated ARF6 endocytic pathway. Cell 111:853-866.
-
(2002)
Cell
, vol.111
, pp. 853-866
-
-
Blagoveshchenskaya, A.D.1
Thomas, L.2
Feliciangeli, S.F.3
Hung, C.H.4
Thomas, G.5
-
10
-
-
0033526798
-
Defective nef alleles in a cohort of hemophiliacs with progressing and nonprogressing HIV-1 infection
-
Brambilla, A., L. Turchetto, A. Gatti, C. Bovolenta, F. Veglia, E. Santagostino, A. Gringeri, M. Clementi, G. Poli, P. Bagnarelli, and E. Vicenzi. 1999. Defective nef alleles in a cohort of hemophiliacs with progressing and nonprogressing HIV-1 infection. Virology 259:349-368.
-
(1999)
Virology
, vol.259
, pp. 349-368
-
-
Brambilla, A.1
Turchetto, L.2
Gatti, A.3
Bovolenta, C.4
Veglia, F.5
Santagostino, E.6
Gringeri, A.7
Clementi, M.8
Poli, G.9
Bagnarelli, P.10
Vicenzi, E.11
-
11
-
-
0035082266
-
Modulation of different human immunodeficiency virus type 1 Nef functions during progression to AIDS
-
Carl, S., T. C. Greenough, M. Krumbiegel, M. Greenberg, J. Skowronski, J. L. Sullivan, and F. Kirchhoff. 2001. Modulation of different human immunodeficiency virus type 1 Nef functions during progression to AIDS. J. Virol. 75:3657-3665.
-
(2001)
J. Virol.
, vol.75
, pp. 3657-3665
-
-
Carl, S.1
Greenough, T.C.2
Krumbiegel, M.3
Greenberg, M.4
Skowronski, J.5
Sullivan, J.L.6
Kirchhoff, F.7
-
12
-
-
0034725614
-
The human thioesterase II protein binds to a site on HIV-1 Nef critical for CD4 down-regulation
-
Cohen, G. B., V. S. Rangan, B. K. Chen, S. Smith, and D. Baltimore. 2000. The human thioesterase II protein binds to a site on HIV-1 Nef critical for CD4 down-regulation. J. Biol. Chem. 275:23097-23105.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 23097-23105
-
-
Cohen, G.B.1
Rangan, V.S.2
Chen, B.K.3
Smith, S.4
Baltimore, D.5
-
13
-
-
0033568473
-
Analysis of the SH3-binding region of HIV-1 nef: Partial functional defects introduced by mutations in the polyproline helix and the hydrophobic pocket
-
Craig, H. M., M. W. Pandori, N. L. Riggs, D. D. Richman, and J. C. Guatelli. 1999. Analysis of the SH3-binding region of HIV-1 nef: partial functional defects introduced by mutations in the polyproline helix and the hydrophobic pocket. Virology 262:55-63.
-
(1999)
Virology
, vol.262
, pp. 55-63
-
-
Craig, H.M.1
Pandori, M.W.2
Riggs, N.L.3
Richman, D.D.4
Guatelli, J.C.5
-
14
-
-
0002929101
-
A model of evolutionary change in proteins
-
M. O. Dayhoff (ed.). The National Biomedical Research Foundation, Silver Spring, Md.
-
Dayhoff, M. O., R. V. Eck, and C. M. Park. 1972. A model of evolutionary change in proteins, p. 89-99. In M. O. Dayhoff (ed.), Atlas of protein sequence and structure, vol. 5. The National Biomedical Research Foundation, Silver Spring, Md.
-
(1972)
Atlas of Protein Sequence and Structure
, vol.5
, pp. 89-99
-
-
Dayhoff, M.O.1
Eck, R.V.2
Park, C.M.3
-
15
-
-
0026645671
-
Absence of selection of HIV-1 variants in vivo based on transcription/transactivation during progression to AIDS
-
Delassus, S., A. Meyerhans, R. Cheynier, and S. Wain-Hobson. 1992. Absence of selection of HIV-1 variants in vivo based on transcription/ transactivation during progression to AIDS. Virology 188:811-818.
-
(1992)
Virology
, vol.188
, pp. 811-818
-
-
Delassus, S.1
Meyerhans, A.2
Cheynier, R.3
Wain-Hobson, S.4
-
16
-
-
0033153464
-
Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions
-
Faclder, O. T., W. Luo, M. Geyer, A. S. Alberts, and B. M. Peterlin. 1999. Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions. Mol. Cell 3:729-739.
-
(1999)
Mol. Cell
, vol.3
, pp. 729-739
-
-
Faclder, O.T.1
Luo, W.2
Geyer, M.3
Alberts, A.S.4
Peterlin, B.M.5
-
17
-
-
0035138509
-
Genetic and functional diversity of human immunodeficiency virus type 1 subtype B Nef primary isolates
-
Foster, J. L., R. P. Molina, T. Luo, V. K. Arora, Y. Huang, D. D. Ho, and J. V. Garcia. 2001. Genetic and functional diversity of human immunodeficiency virus type 1 subtype B Nef primary isolates. J. Virol. 75:1672-1680.
-
(2001)
J. Virol.
, vol.75
, pp. 1672-1680
-
-
Foster, J.L.1
Molina, R.P.2
Luo, T.3
Arora, V.K.4
Huang, Y.5
Ho, D.D.6
Garcia, J.V.7
-
18
-
-
0025733252
-
Serine phosphorylation-independent downregulation of cell-surface CD4 by nef
-
Garcia, J. V., and A. D. Miller. 1991. Serine phosphorylation-independent downregulation of cell-surface CD4 by nef. Nature 350:508-511.
-
(1991)
Nature
, vol.350
, pp. 508-511
-
-
Garcia, J.V.1
Miller, A.D.2
-
19
-
-
0034693935
-
Functional and structural defects in HIV type 1 nef genes derived from pediatric long-term survivors
-
Geffin, R., D. Wolf, R. Muller, M. D. Hill, E. Stellwag, M. Freitag, G. Sass, G. B. Scott, and A. S. Baur. 2000. Functional and structural defects in HIV type 1 nef genes derived from pediatric long-term survivors. AIDS Res. Hum. Retrovir. 16:1855-1868.
-
(2000)
AIDS Res. Hum. Retrovir.
, vol.16
, pp. 1855-1868
-
-
Geffin, R.1
Wolf, D.2
Muller, R.3
Hill, M.D.4
Stellwag, E.5
Freitag, M.6
Sass, G.7
Scott, G.B.8
Baur, A.S.9
-
20
-
-
0035848864
-
HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell
-
Geleziunas, R., W. Xu, K. Takeda, H. Ichijo, and W. C. Greene. 2001. HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell. Nature 410:834-838.
-
(2001)
Nature
, vol.410
, pp. 834-838
-
-
Geleziunas, R.1
Xu, W.2
Takeda, K.3
Ichijo, H.4
Greene, W.C.5
-
21
-
-
0034894379
-
Structure-function relationships in HIV-1 Nef
-
Geyer, M., O. T. Fackler, and B. M. Peterlin. 2001. Structure-function relationships in HIV-1 Nef. EMBO Rep. 2:580-585.
-
(2001)
EMBO Rep.
, vol.2
, pp. 580-585
-
-
Geyer, M.1
Fackler, O.T.2
Peterlin, B.M.3
-
22
-
-
0032525137
-
The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes
-
Greenberg, M. E., A. J. Iafrate, and J. Skowronski. 1998. The SH3 domain-binding surface and an acidic motif in HIV-1 Nef regulate trafficking of class I MHC complexes. EMBO J. 17:2777-2789.
-
(1998)
EMBO J.
, vol.17
, pp. 2777-2789
-
-
Greenberg, M.E.1
Iafrate, A.J.2
Skowronski, J.3
-
23
-
-
4644242776
-
The brightening future of HIV therapeutics
-
Greene, W. C. 2004. The brightening future of HIV therapeutics. Nat. Immunol. 5:867-871.
-
(2004)
Nat. Immunol.
, vol.5
, pp. 867-871
-
-
Greene, W.C.1
-
24
-
-
0030980288
-
Refined solution structure and backbone dynamics of HIV-1 Nef
-
Grzesiek, S., A. Bax, J. S. Hu, J. Kaufman, I. Palmer, S. J. Stahl, N. Tjandra, and P. T. Wingfield. 1997. Refined solution structure and backbone dynamics of HIV-1 Nef. Protein Sci. 6:1248-1263.
-
(1997)
Protein Sci.
, vol.6
, pp. 1248-1263
-
-
Grzesiek, S.1
Bax, A.2
Hu, J.S.3
Kaufman, J.4
Palmer, I.5
Stahl, S.J.6
Tjandra, N.7
Wingfield, P.T.8
-
25
-
-
0028908766
-
Characterization of nef sequences in long-term survivors of human immunodeficiency virus type 1 infection
-
Huang, Y., L. Zhang, and D. D. Ho. 1995. Characterization of nef sequences in long-term survivors of human immunodeficiency virus type 1 infection. J. Virol. 69:93-100.
-
(1995)
J. Virol.
, vol.69
, pp. 93-100
-
-
Huang, Y.1
Zhang, L.2
Ho, D.D.3
-
26
-
-
0031039979
-
Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling
-
Iafrate, A. J., S. Bronson, and J. Skowronski. 1997. Separable functions of Nef disrupt two aspects of T cell receptor machinery: CD4 expression and CD3 signaling. EMBO J. 16:673-684.
-
(1997)
EMBO J.
, vol.16
, pp. 673-684
-
-
Iafrate, A.J.1
Bronson, S.2
Skowronski, J.3
-
27
-
-
19344363916
-
HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis
-
Janardhan, A., T. Swigut, B. Hill, M. P. Myers, and J. Skowronski. 2004. HIV-1 Nef binds the DOCK2-ELMO1 complex to activate rac and inhibit lymphocyte chemotaxis. PLoS Biol. 2:E6.
-
(2004)
PLoS Biol.
, vol.2
-
-
Janardhan, A.1
Swigut, T.2
Hill, B.3
Myers, M.P.4
Skowronski, J.5
-
28
-
-
0035080263
-
Nef-induced CD4 downregulation: A diacidic sequence in human immunodeficiency virus type 1 Nef does not function as a protein sorting motif through direct binding to beta-COP
-
Janvier, K., H. Craig, S. Le Gall, R. Benarous, J. Guatelli, O. Schwartz, and S. Benichou. 2001. Nef-induced CD4 downregulation: a diacidic sequence in human immunodeficiency virus type 1 Nef does not function as a protein sorting motif through direct binding to beta-COP. J. Virol. 75:3971-3976.
-
(2001)
J. Virol.
, vol.75
, pp. 3971-3976
-
-
Janvier, K.1
Craig, H.2
Le Gall, S.3
Benarous, R.4
Guatelli, J.5
Schwartz, O.6
Benichou, S.7
-
29
-
-
0026562720
-
Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene
-
Kimpton, J., and M. Emerman. 1992. Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitive cell line on the basis of activation of an integrated beta-galactosidase gene. J. Virol. 66:2232-2239.
-
(1992)
J. Virol.
, vol.66
, pp. 2232-2239
-
-
Kimpton, J.1
Emerman, M.2
-
30
-
-
0033052038
-
Sequence variations in human immunodeficiency virus type 1 Nef are associated with different stages of disease
-
Kirchhoff, F., P. J. Easterbrook, N. Douglas, M. Troop, T. C. Greenough, J. Weber, S. Carl, J. L. Sullivan, and R. S. Daniels. 1999. Sequence variations in human immunodeficiency virus type 1 Nef are associated with different stages of disease. J. Virol. 73:5497-5508.
-
(1999)
J. Virol.
, vol.73
, pp. 5497-5508
-
-
Kirchhoff, F.1
Easterbrook, P.J.2
Douglas, N.3
Troop, M.4
Greenough, T.C.5
Weber, J.6
Carl, S.7
Sullivan, J.L.8
Daniels, R.S.9
-
31
-
-
0035162494
-
Evolutionary and immunological implications of contemporary HIV-1 variation
-
Korber, B., B. Gaschen, K. Yusim, R. Thakallapally, C. Kesmir, and V. Detours. 2001. Evolutionary and immunological implications of contemporary HIV-1 variation. Br. Med. Bull. 58:19-42.
-
(2001)
Br. Med. Bull.
, vol.58
, pp. 19-42
-
-
Korber, B.1
Gaschen, B.2
Yusim, K.3
Thakallapally, R.4
Kesmir, C.5
Detours, V.6
-
32
-
-
0032546809
-
Limitations of a molecular clock applied to considerations of the origin of HIV-1
-
Korber, B., J. Theiler, and S. Wolinsky. 1998. Limitations of a molecular clock applied to considerations of the origin of HIV-1. Science 280:1868-1871.
-
(1998)
Science
, vol.280
, pp. 1868-1871
-
-
Korber, B.1
Theiler, J.2
Wolinsky, S.3
-
33
-
-
0030836543
-
Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques
-
Lang, S. M., A. J. Iafrate, C. Stahl-Hennig, E. M. Kuhn, T. Nisslein, F. J. Kaup, M. Haupt, G. Hunsmann, J. Skowronski, and F. Kirchhoff. 1997. Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques. Nat. Med. 3:860-865.
-
(1997)
Nat. Med.
, vol.3
, pp. 860-865
-
-
Lang, S.M.1
Iafrate, A.J.2
Stahl-Hennig, C.3
Kuhn, E.M.4
Nisslein, T.5
Kaup, F.J.6
Haupt, M.7
Hunsmann, G.8
Skowronski, J.9
Kirchhoff, F.10
-
34
-
-
0025815375
-
Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: Identification of replication-competent and -defective viral genomes
-
Li, Y., J. C. Kappes, J. A. Conway, R. W. Price, G. M. Shaw, and B. H. Hahn. 1991. Molecular characterization of human immunodeficiency virus type 1 cloned directly from uncultured human brain tissue: identification of replication-competent and -defective viral genomes. J. Virol. 65:3973-3985.
-
(1991)
J. Virol.
, vol.65
, pp. 3973-3985
-
-
Li, Y.1
Kappes, J.C.2
Conway, J.A.3
Price, R.W.4
Shaw, G.M.5
Hahn, B.H.6
-
35
-
-
19244382596
-
Mutation of a conserved residue (D123) required for oligomerization of human immunodeficiency virus type 1 Nef protein abolishes interaction with human thioesterase and results in impairment of Nef biological functions
-
Liu, L. X., N. Heveker, O. T. Fackler, S. Arold, S. Le Gall, K. Janvier, B. M. Peterlin, C. Dumas, O. Schwartz, S. Benichou, and R. Benarous. 2000. Mutation of a conserved residue (D123) required for oligomerization of human immunodeficiency virus type 1 Nef protein abolishes interaction with human thioesterase and results in impairment of Nef biological functions. J. Virol. 74:5310-5319.
-
(2000)
J. Virol.
, vol.74
, pp. 5310-5319
-
-
Liu, L.X.1
Heveker, N.2
Fackler, O.T.3
Arold, S.4
Le Gall, S.5
Janvier, K.6
Peterlin, B.M.7
Dumas, C.8
Schwartz, O.9
Benichou, S.10
Benarous, R.11
-
36
-
-
0030831097
-
Infectivity enhancement by human immunodeficiency virus type 1 Nef is independent of its association with a cellular serine/threonine kinase
-
Luo, T., R. A. Livingston, and J. V. Garcia. 1997. Infectivity enhancement by human immunodeficiency virus type 1 Nef is independent of its association with a cellular serine/threonine kinase. J. Virol. 71:9524-9530.
-
(1997)
J. Virol.
, vol.71
, pp. 9524-9530
-
-
Luo, T.1
Livingston, R.A.2
Garcia, J.V.3
-
37
-
-
0032566903
-
SH3-domain binding function of HIV-1 Nef is required for association with a PAK-related kinase
-
Manninen, A., M. Hiipakka, M. Vihinen, W. Lu, B. J. Mayer, and K. Saksela. 1998. SH3-domain binding function of HIV-1 Nef is required for association with a PAK-related kinase. Virology 250:273-282.
-
(1998)
Virology
, vol.250
, pp. 273-282
-
-
Manninen, A.1
Hiipakka, M.2
Vihinen, M.3
Lu, W.4
Mayer, B.J.5
Saksela, K.6
-
38
-
-
0028853962
-
Functional characterization of human immunodeficiency virus type 1 nef genes in patients with divergent rates of disease progression
-
Michael, N. L., G. Chang, L. A. d'Arcy, C. J. Tseng, D. L. Birx, and H. W. Sheppard. 1995. Functional characterization of human immunodeficiency virus type 1 nef genes in patients with divergent rates of disease progression. J. Virol. 69:6758-6769.
-
(1995)
J. Virol.
, vol.69
, pp. 6758-6769
-
-
Michael, N.L.1
Chang, G.2
D'Arcy, L.A.3
Tseng, C.J.4
Birx, D.L.5
Sheppard, H.W.6
-
39
-
-
0026319199
-
Protein folding and association: Insights from the interfacial and thermodynamic properties of hydrocarbons
-
Nicholls, A., K. A. Sharp, and B. Honig. 1991. Protein folding and association: insights from the interfacial and thermodynamic properties of hydrocarbons. Proteins 11:281-296.
-
(1991)
Proteins
, vol.11
, pp. 281-296
-
-
Nicholls, A.1
Sharp, K.A.2
Honig, B.3
-
40
-
-
0036094391
-
Human immunodeficiency virus type 1 subtype C molecular phylogeny: Consensus sequence for an AIDS vaccine design?
-
Novitsky, V., U. R. Smith, P. Gilbert, M. F. McLane, P. Chigwedere, C. Williamson, T. Ndung'u, I. Klein, S. Y. Chang, T. Peter, I. Thior, B. T. Foley, S. Gaolekwe, N. Rybak, S. Gaseitsiwe, F. Vannberg, R. Marlink, T. H. Lee, and M. Essex. 2002. Human immunodeficiency virus type 1 subtype C molecular phylogeny: consensus sequence for an AIDS vaccine design? J. Virol. 76:5435-5451.
-
(2002)
J. Virol.
, vol.76
, pp. 5435-5451
-
-
Novitsky, V.1
Smith, U.R.2
Gilbert, P.3
McLane, M.F.4
Chigwedere, P.5
Williamson, C.6
Ndung'U, T.7
Klein, I.8
Chang, S.Y.9
Peter, T.10
Thior, I.11
Foley, B.T.12
Gaolekwe, S.13
Rybak, N.14
Gaseitsiwe, S.15
Vannberg, F.16
Marlink, R.17
Lee, T.H.18
Essex, M.19
-
41
-
-
1642465048
-
Genetic diversity of HIV in Africa: Impact on diagnosis, treatment, vaccine development and trials
-
Peeters, M., C. Toure-Kane, and J. N. Nkengasong. 2003. Genetic diversity of HIV in Africa: impact on diagnosis, treatment, vaccine development and trials. AIDS 17:2547-2560.
-
(2003)
AIDS
, vol.17
, pp. 2547-2560
-
-
Peeters, M.1
Toure-Kane, C.2
Nkengasong, J.N.3
-
42
-
-
0033515427
-
Nef-induced CD4 degradation: A diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes
-
Piguet, V., F. Gu, M. Foti, N. Demaurex, J. Gruenberg, J. L. Carpentier, and D. Trono. 1999. Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of beta-COP in endosomes. Cell 97:63-73.
-
(1999)
Cell
, vol.97
, pp. 63-73
-
-
Piguet, V.1
Gu, F.2
Foti, M.3
Demaurex, N.4
Gruenberg, J.5
Carpentier, J.L.6
Trono, D.7
-
43
-
-
0033776709
-
HIV-1 Nef protein binds to the cellular protein PACS-1 to down-regulate class I major histocompatibility complexes
-
Piguet, V., L. Wan, C. Borel, A. Mangasarian, N. Demaurex, G. Thomas, and D. Trono. 2000. HIV-1 Nef protein binds to the cellular protein PACS-1 to down-regulate class I major histocompatibility complexes. Nat. Cell Biol. 2:163-167.
-
(2000)
Nat. Cell Biol.
, vol.2
, pp. 163-167
-
-
Piguet, V.1
Wan, L.2
Borel, C.3
Mangasarian, A.4
Demaurex, N.5
Thomas, G.6
Trono, D.7
-
44
-
-
8644224930
-
Nef associates with p21-activated kinase 2 in a p21-GTPase-dependent dynamic activation complex within lipid rafts
-
Pulkkinen, K., G. H. Renkema, F. Kirchhoff, and K. Saksela. 2004. Nef associates with p21-activated kinase 2 in a p21-GTPase-dependent dynamic activation complex within lipid rafts. J. Virol. 78:12773-12780.
-
(2004)
J. Virol.
, vol.78
, pp. 12773-12780
-
-
Pulkkinen, K.1
Renkema, G.H.2
Kirchhoff, F.3
Saksela, K.4
-
45
-
-
0034134113
-
Interactions of HIV-1 NEF with cellular signal transducing proteins
-
Renkema, G. H., and K. Saksela. 2000. Interactions of HIV-1 NEF with cellular signal transducing proteins. Front. Biosci. 5:D268-D283.
-
(2000)
Front. Biosci.
, vol.5
-
-
Renkema, G.H.1
Saksela, K.2
-
46
-
-
0027958148
-
Human immunodeficiency virus type 1 Nef associates with a cellular serine kinase in T lymphocytes
-
Sawai, E. T., A. Baur, H. Struble, B. M. Peterlin, J. A. Levy, and C. Cheng-Mayer. 1994. Human immunodeficiency virus type 1 Nef associates with a cellular serine kinase in T lymphocytes. Proc. Natl. Acad. Sci. USA 91:1539-1543.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 1539-1543
-
-
Sawai, E.T.1
Baur, A.2
Struble, H.3
Peterlin, B.M.4
Levy, J.A.5
Cheng-Mayer, C.6
-
47
-
-
0029064101
-
A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinase activity
-
Sawai, E. T., A. S. Baur, B. M. Peterlin, J. A. Levy, and C. Cheng-Mayer. 1995. A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinase activity. J. Biol. Chem. 270:15307-15314.
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 15307-15314
-
-
Sawai, E.T.1
Baur, A.S.2
Peterlin, B.M.3
Levy, J.A.4
Cheng-Mayer, C.5
-
48
-
-
0030292953
-
Activation of PAK by HIV and SIV Nef: Importance for AIDS in rhesus macaques
-
Sawai, E. T., I. H. Khan, P. M. Montbriand, B. M. Peterlin, C. Cheng-Mayer, and P. A. Luciw. 1996. Activation of PAK by HIV and SIV Nef: importance for AIDS in rhesus macaques. Curr. Biol. 6:1519-1527.
-
(1996)
Curr. Biol.
, vol.6
, pp. 1519-1527
-
-
Sawai, E.T.1
Khan, I.H.2
Montbriand, P.M.3
Peterlin, B.M.4
Cheng-Mayer, C.5
Luciw, P.A.6
-
49
-
-
0027259393
-
Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivo
-
Shugars, D. C., M. S. Smith, D. H. Glueck, P. V. Nantermet, F. Seillier-Moiseiwitsch, and R. Swanstrom. 1993. Analysis of human immunodeficiency virus type 1 nef gene sequences present in vivo. J. Virol. 67:4639-4650.
-
(1993)
J. Virol.
, vol.67
, pp. 4639-4650
-
-
Shugars, D.C.1
Smith, M.S.2
Glueck, D.H.3
Nantermet, P.V.4
Seillier-Moiseiwitsch, F.5
Swanstrom, R.6
-
50
-
-
0141993006
-
Signaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell development
-
Stove, V., E. Naessens, C. Stove, T. Swigut, J. Plum, and B. Verhasselt. 2003. Signaling but not trafficking function of HIV-1 protein Nef is essential for Nef-induced defects in human intrathymic T-cell development. Blood 102:2925-2932.
-
(2003)
Blood
, vol.102
, pp. 2925-2932
-
-
Stove, V.1
Naessens, E.2
Stove, C.3
Swigut, T.4
Plum, J.5
Verhasselt, B.6
-
51
-
-
0034034278
-
Simian and human immunodeficiency virus Nef proteins use different surfaces to downregulate class I major histocompatibility complex antigen expression
-
Swigut, T., A. J. Iafrate, J. Muench, F. Kirchhoff, and J. Skowronski. 2000. Simian and human immunodeficiency virus Nef proteins use different surfaces to downregulate class I major histocompatibility complex antigen expression. J. Virol. 74:5691-5701.
-
(2000)
J. Virol.
, vol.74
, pp. 5691-5701
-
-
Swigut, T.1
Iafrate, A.J.2
Muench, J.3
Kirchhoff, F.4
Skowronski, J.5
-
52
-
-
10644261241
-
Human immunodeficiency virus type 1 Nef domains required for disruption of major histocompatibility complex class 1 trafficking are also necessary for coprecipitation of Nef with HLA-A2
-
Williams, M., J. F. Roeth, M. R. Kasper, T. M. Filzen, and K. L. Collins. 2005. Human immunodeficiency virus type 1 Nef domains required for disruption of major histocompatibility complex class 1 trafficking are also necessary for coprecipitation of Nef with HLA-A2. J. Virol. 79:632-636.
-
(2005)
J. Virol.
, vol.79
, pp. 632-636
-
-
Williams, M.1
Roeth, J.F.2
Kasper, M.R.3
Filzen, T.M.4
Collins, K.L.5
-
53
-
-
0030273317
-
HIV-1 Nef association with cellular serine kinase correlates with enhanced virion infectivity and efficient proviral DNA synthesis
-
Wiskerchen, M., and C. Cheng-Mayer. 1996. HIV-1 Nef association with cellular serine kinase correlates with enhanced virion infectivity and efficient proviral DNA synthesis. Virology 224:292-301.
-
(1996)
Virology
, vol.224
, pp. 292-301
-
-
Wiskerchen, M.1
Cheng-Mayer, C.2
-
54
-
-
10744228109
-
HIV-1 Nef mimics an integrin receptor signal that recruits the polycomb group protein Eed to the plasma membrane
-
Witte, V., B. Laffert, O. Rosorius, P. Lischka, K. Blume, G. Galler, A. Stilper, D. Willbold, P. D'Aloja, M. Sixt, J. Kolanus, M. Ott, W. Kolanus, G. Schuler, and A. S. Baur. 2004. HIV-1 Nef mimics an integrin receptor signal that recruits the polycomb group protein Eed to the plasma membrane. Mol. Cell 13:179-190.
-
(2004)
Mol. Cell
, vol.13
, pp. 179-190
-
-
Witte, V.1
Laffert, B.2
Rosorius, O.3
Lischka, P.4
Blume, K.5
Galler, G.6
Stilper, A.7
Willbold, D.8
D'Aloja, P.9
Sixt, M.10
Kolanus, J.11
Ott, M.12
Kolanus, W.13
Schuler, G.14
Baur, A.S.15
-
55
-
-
0035173735
-
HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce antiapoptotic signals
-
Wolf, D., V. Witte, B. Laffert, K. Blume, E. Stromer, S. Trapp, P. d'Aloja, A. Schurmann, and A. S. Baur. 2001. HIV-1 Nef associated PAK and PI3-kinases stimulate Akt-independent Bad-phosphorylation to induce antiapoptotic signals. Nat. Med. 7:1217-1224.
-
(2001)
Nat. Med.
, vol.7
, pp. 1217-1224
-
-
Wolf, D.1
Witte, V.2
Laffert, B.3
Blume, K.4
Stromer, E.5
Trapp, S.6
D'Aloja, P.7
Schurmann, A.8
Baur, A.S.9
-
56
-
-
0032484908
-
An African HIV-1 sequence from 1959 and implications for the origin of the epidemic
-
Zhu, T., B. T. Korber, A. J. Nahmias, E. Hooper, P. M. Sharp, and D. D. Ho. 1998. An African HIV-1 sequence from 1959 and implications for the origin of the epidemic. Nature 391:594-597.
-
(1998)
Nature
, vol.391
, pp. 594-597
-
-
Zhu, T.1
Korber, B.T.2
Nahmias, A.J.3
Hooper, E.4
Sharp, P.M.5
Ho, D.D.6
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