메뉴 건너뛰기




Volumn 85, Issue 6, 2004, Pages 1463-1469

Multiple human immunodeficiency virus type 1 Nef functions contribute to efficient replication in primary human macrophages

Author keywords

[No Author keywords available]

Indexed keywords

CD4 ANTIGEN; NEF PROTEIN; PHOSPHOTRANSFERASE;

EID: 2942635646     PISSN: 00221317     EISSN: None     Source Type: Journal    
DOI: 10.1099/vir.0.79946-0     Document Type: Article
Times cited : (12)

References (68)
  • 1
    • 0029015330 scopus 로고
    • Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis
    • Aiken, C. & Trono, D. (1995). Nef stimulates human immunodeficiency virus type 1 proviral DNA synthesis. J Virol 69, 5048-5056.
    • (1995) J. Virol. , vol.69 , pp. 5048-5056
    • Aiken, C.1    Trono, D.2
  • 2
    • 0030788298 scopus 로고    scopus 로고
    • A role for natural simian immunodeficiency virus and human immunodeficiency virus type 1 nef alleles in lymphocyte activation
    • Alexander, L., Du, Z., Rosenzweig, M., Jung, J. U. & Desrosiers, R. C. (1997). A role for natural simian immunodeficiency virus and human immunodeficiency virus type 1 nef alleles in lymphocyte activation. J Virol 71, 6094-6099.
    • (1997) J. Virol. , vol.71 , pp. 6094-6099
    • Alexander, L.1    Du, Z.2    Rosenzweig, M.3    Jung, J.U.4    Desrosiers, R.C.5
  • 3
    • 0030750548 scopus 로고    scopus 로고
    • Inhibition of replication of HIV in primary monocyte/macrophages by different antiviral drugs and comparative efficacy in lymphocytes
    • 7 other authors
    • Aquaro, S., Perno, C. F., Balestra, E. & 7 other authors (1997). Inhibition of replication of HIV in primary monocyte/macrophages by different antiviral drugs and comparative efficacy in lymphocytes. J Leukoc Biol 62, 138-143.
    • (1997) J. Leukoc. Biol. , vol.62 , pp. 138-143
    • Aquaro, S.1    Perno, C.F.2    Balestra, E.3
  • 4
    • 0030887932 scopus 로고    scopus 로고
    • The N-terminus of Nef from HIV-1/SIV associates with a protein complex containing Lck and a serine kinase
    • Baur, A. S., Sass, G., Laffert, B., Willbold, D., Cheng, M. C. & Peterlin, B. M. (1997). The N-terminus of Nef from HIV-1/SIV associates with a protein complex containing Lck and a serine kinase. Immunity 6, 283-291.
    • (1997) Immunity , vol.6 , pp. 283-291
    • Baur, A.S.1    Sass, G.2    Laffert, B.3    Willbold, D.4    Cheng, M.C.5    Peterlin, B.M.6
  • 5
    • 0031791917 scopus 로고    scopus 로고
    • Association of simian immunodeficiency virus Nef with the T-cell receptor (TCR) ζ chain leads to TCR down-modulation
    • Bell, I., Ashman, C., Maughan, J., Hooker, E., Cook, F. & Reinhart, T. A. (1998). Association of simian immunodeficiency virus Nef with the T-cell receptor (TCR) ζ chain leads to TCR down-modulation. J Gen Virol 79, 2717-2727.
    • (1998) J. Gen. Virol. , vol.79 , pp. 2717-2727
    • Bell, I.1    Ashman, C.2    Maughan, J.3    Hooker, E.4    Cook, F.5    Reinhart, T.A.6
  • 6
    • 0032750417 scopus 로고    scopus 로고
    • Activation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complex
    • Brown, A., Wang, X., Sawai, E. & Cheng-Mayer, C. (1999). Activation of the PAK-related kinase by human immunodeficiency virus type 1 Nef in primary human peripheral blood lymphocytes and macrophages leads to phosphorylation of a PIX-p95 complex. J Virol 73, 9899-9907.
    • (1999) J. Virol. , vol.73 , pp. 9899-9907
    • Brown, A.1    Wang, X.2    Sawai, E.3    Cheng-Mayer, C.4
  • 7
    • 0025004459 scopus 로고
    • Viral determinants of human immunodeficiency virus type I T-cell and macrophage tropism, cytopathogenicity, and CD4 antigen modulation
    • Cheng-Mayer, C., Quiroga, M., Tung, J. W., Dina, D. & Levy, J. A. (1990). Viral determinants of human immunodeficiency virus type I T-cell and macrophage tropism, cytopathogenicity, and CD4 antigen modulation. J Virol 64, 4390-4398.
    • (1990) J. Virol. , vol.64 , pp. 4390-4398
    • Cheng-Mayer, C.1    Quiroga, M.2    Tung, J.W.3    Dina, D.4    Levy, J.A.5
  • 8
    • 0028302998 scopus 로고
    • Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene
    • Chowers, M. Y., Spina, C. A., Kwoh, T. J., Fitch, N. J. S., Richman, D. D. & Guateli, J. C. (1994). Optimal infectivity in vitro of human immunodeficiency virus type 1 requires an intact nef gene. J Virol 68, 2906-2914.
    • (1994) J. Virol. , vol.68 , pp. 2906-2914
    • Chowers, M.Y.1    Spina, C.A.2    Kwoh, T.J.3    Fitch, N.J.S.4    Richman, D.D.5    Guateli, J.C.6
  • 10
    • 0037127303 scopus 로고    scopus 로고
    • Cell surface CD4 interferes with the infectivity of HIV-1 particles released from T cells
    • Cortes, M., Wong-Staal, F. & Lama, J. (2002). Cell surface CD4 interferes with the infectivity of HIV-1 particles released from T cells. J Biol Chem 277, 1770-1779.
    • (2002) J. Biol. Chem. , vol.277 , pp. 1770-1779
    • Cortes, M.1    Wong-Staal, F.2    Lama, J.3
  • 11
    • 0033568473 scopus 로고    scopus 로고
    • Analysis of the SH3-binding region of HIV-1 Nef: Partial functional defects introduced by mutations in the polyproline helix and the hydrophobic pocket
    • Craig, H., Pandori, M., Riggs, N. L., Richman, D. D. & Guatelli, J. (1999). Analysis of the SH3-binding region of HIV-1 Nef: Partial functional defects introduced by mutations in the polyproline helix and the hydrophobic pocket. Virology 262, 55-63.
    • (1999) Virology , vol.262 , pp. 55-63
    • Craig, H.1    Pandori, M.2    Riggs, N.L.3    Richman, D.D.4    Guatelli, J.5
  • 12
    • 0028804160 scopus 로고
    • Genomic structure of an attenuated quasi species from a blood transfusion donor and recipients
    • 17 other authors
    • Deacon, N. J., Tsykin, A., Solomon, A. & 17 other authors (1995). Genomic structure of an attenuated quasi species from a blood transfusion donor and recipients. Science 270, 988-991.
    • (1995) Science , vol.270 , pp. 988-991
    • Deacon, N.J.1    Tsykin, A.2    Solomon, A.3
  • 13
    • 0033153464 scopus 로고    scopus 로고
    • Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions
    • Fackler, O. T., Luo, W., Geyer, M., Alberts, A. S. & Peterlin, B. M. (1999). Activation of Vav by Nef induces cytoskeletal rearrangements and downstream effector functions. Mol Cell 3, 729-739.
    • (1999) Mol. Cell. , vol.3 , pp. 729-739
    • Fackler, O.T.1    Luo, W.2    Geyer, M.3    Alberts, A.S.4    Peterlin, B.M.5
  • 14
    • 0037321831 scopus 로고    scopus 로고
    • The HIV-TSG101 interface: Recent advances in a budding field
    • Freed, E. O. (2003). The HIV-TSG101 interface: recent advances in a budding field. Trends Microbiol 11, 56-59.
    • (2003) Trends Microbiol. , vol.11 , pp. 56-59
    • Freed, E.O.1
  • 15
    • 0025733252 scopus 로고
    • Serine phosphorylation-independent downregulation of cell-surface CD4 by nef
    • Garcia, J. V. & Miller, A. D. (1991). Serine phosphorylation-independent downregulation of cell-surface CD4 by nef. Nature 350, 508-511.
    • (1991) Nature , vol.350 , pp. 508-511
    • Garcia, J.V.1    Miller, A.D.2
  • 17
    • 0023099283 scopus 로고
    • Fine structure of human immunodeficiency virus (HIV) and immunolocalization of structural proteins
    • Gelderblom, H. R., Hausmann, E. H., Ozel, M., Pauli, G. & Koch, M. A. (1987). Fine structure of human immunodeficiency virus (HIV) and immunolocalization of structural proteins. Virology 156, 171-176.
    • (1987) Virology , vol.156 , pp. 171-176
    • Gelderblom, H.R.1    Hausmann, E.H.2    Ozel, M.3    Pauli, G.4    Koch, M.A.5
  • 18
    • 0035848864 scopus 로고    scopus 로고
    • HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell
    • Geleziunas, R., Xu, W., Tkeda, K., Ichijo, H. & Greene, W. C. (2001). HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell. Nature 410, 834-838.
    • (2001) Nature , vol.410 , pp. 834-838
    • Geleziunas, R.1    Xu, W.2    Tkeda, K.3    Ichijo, H.4    Greene, W.C.5
  • 20
    • 0029046227 scopus 로고
    • Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef
    • Goldsmith, M. A., Warmerdam, M. T., Atchison, R. E., Miller, M. D. & Greene, W. C. (1995). Dissociation of the CD4 downregulation and viral infectivity enhancement functions of human immunodeficiency virus type 1 Nef. J Virol 69, 4112-4121.
    • (1995) J. Virol. , vol.69 , pp. 4112-4121
    • Goldsmith, M.A.1    Warmerdam, M.T.2    Atchison, R.E.3    Miller, M.D.4    Greene, W.C.5
  • 21
    • 0028887886 scopus 로고
    • Human immunodeficiency virus type 1 Nef protein inhibits activation pathways in peripheral blood mononuclear cells and T-cell lines
    • Greenway, A. L., Azad, A. & McPhee, D. A. (1995). Human immunodeficiency virus type 1 Nef protein inhibits activation pathways in peripheral blood mononuclear cells and T-cell lines. J Virol 69, 1842-1850.
    • (1995) J. Virol. , vol.69 , pp. 1842-1850
    • Greenway, A.L.1    Azad, A.2    McPhee, D.A.3
  • 22
    • 0029795040 scopus 로고    scopus 로고
    • The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef: Mapping of the Nef binding surface by NMR
    • Grzesiek, S., Stahl, S. J., Wingfield, P. T. & Bax, A. (1996). The CD4 determinant for downregulation by HIV-1 Nef directly binds to Nef: mapping of the Nef binding surface by NMR. Biochemistry 35, 163-175.
    • (1996) Biochemistry , vol.35 , pp. 163-175
    • Grzesiek, S.1    Stahl, S.J.2    Wingfield, P.T.3    Bax, A.4
  • 23
    • 0023659754 scopus 로고
    • HIV F/3′ orf encodes a phosphorylated GTP-binding protein resembling an oncogene product
    • Guy, B., Kieny, M. P., Riviere, Y., Le Peuch, C., Dott, K., Girard, M., Montagnier, L. & Lecocq, J. P. (1987). HIV F/3′ orf encodes a phosphorylated GTP-binding protein resembling an oncogene product. Nature 330, 266-269.
    • (1987) Nature , vol.330 , pp. 266-269
    • Guy, B.1    Kieny, M.P.2    Riviere, Y.3    Le Peuch, C.4    Dott, K.5    Girard, M.6    Montagnier, L.7    Lecocq, J.P.8
  • 24
    • 0034843329 scopus 로고    scopus 로고
    • The pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck
    • Hanna, Z., Weng, X., Kay, D. G., Poudrier, J., Lowell, C. & Jolicoeur, P. (2001). The pathogenicity of human immunodeficiency virus (HIV) type 1 Nef in CD4C/HIV transgenic mice is abolished by mutation of its SH3-binding domain, and disease development is delayed in the absence of Hck. J Virol 75, 9378-9392.
    • (2001) J. Virol. , vol.75 , pp. 9378-9392
    • Hanna, Z.1    Weng, X.2    Kay, D.G.3    Poudrier, J.4    Lowell, C.5    Jolicoeur, P.6
  • 25
    • 0031786925 scopus 로고    scopus 로고
    • Vpx is required for dissemination and pathogenesis of SIV(SM) PBj: Evidence of macrophage-dependent viral amplification
    • 8 other authors
    • Hirsch, V. M., Sharkey, M. E., Brown, C. R. & 8 other authors (1998). Vpx is required for dissemination and pathogenesis of SIV(SM) PBj: evidence of macrophage-dependent viral amplification. Nat Med 4, 1401-1408.
    • (1998) Nat. Med. , vol.4 , pp. 1401-1408
    • Hirsch, V.M.1    Sharkey, M.E.2    Brown, C.R.3
  • 26
    • 0022551277 scopus 로고
    • Infection of monocyte/macrophages by human T lymphotrophic virus type III
    • Ho, D. D., Rota, T. R. & Hirsch, M. S. (1986). Infection of monocyte/macrophages by human T lymphotrophic virus type III. J Clin Invest 77, 1712-1715.
    • (1986) J. Clin. Invest. , vol.77 , pp. 1712-1715
    • Ho, D.D.1    Rota, T.R.2    Hirsch, M.S.3
  • 27
    • 0031774858 scopus 로고    scopus 로고
    • Zeta chain of the T-cell receptor interacts with Nef of simian immunodeficiency virus and human immunodeficiency virus type 2
    • Howe, A. Y., Jung, J. U. & Desrosiers, R. C. (1998). Zeta chain of the T-cell receptor interacts with Nef of simian immunodeficiency virus and human immunodeficiency virus type 2. J Virol 72, 9827-9834.
    • (1998) J. Virol. , vol.72 , pp. 9827-9834
    • Howe, A.Y.1    Jung, J.U.2    Desrosiers, R.C.3
  • 28
    • 0030958508 scopus 로고    scopus 로고
    • Identification of regions in HIV-1 Nef required for efficient downregulation of cell Surface CD4
    • Hua, J., Blair, W., Truant, R. & Cullen, B. R. (1997). Identification of regions in HIV-1 Nef required for efficient downregulation of cell Surface CD4. Virology 231, 231-238.
    • (1997) Virology , vol.231 , pp. 231-238
    • Hua, J.1    Blair, W.2    Truant, R.3    Cullen, B.R.4
  • 29
    • 0036776530 scopus 로고    scopus 로고
    • Increased macrophage infection upon subcutaneous inoculation of rhesus macaques with simian immunodeficiency virus-loaded dendritic cells or T cells but not with cell-free virus
    • 9 other authors
    • Ignatius, R., Tenner-Racz, K., Messmer, D. & 9 other authors (2002). Increased macrophage infection upon subcutaneous inoculation of rhesus macaques with simian immunodeficiency virus-loaded dendritic cells or T cells but not with cell-free virus. J Virol 76, 9787-9797.
    • (2002) J. Virol. , vol.76 , pp. 9787-9797
    • Ignatius, R.1    Tenner-Racz, K.2    Messmer, D.3
  • 30
    • 0035912198 scopus 로고    scopus 로고
    • Pathways to neuronal injury and apoptosis in HIV-associated dementia
    • Kaul, M., Garden, G. A. & Lipton, S. A. (2001). Pathways to neuronal injury and apoptosis in HIV-associated dementia. Nature 410, 988-994.
    • (2001) Nature , vol.410 , pp. 988-994
    • Kaul, M.1    Garden, G.A.2    Lipton, S.A.3
  • 31
    • 0030820125 scopus 로고    scopus 로고
    • Mutational analysis of human immunodeficiency virus type 1 (HIV-1) accessory genes: Requirement of a site in the nef gene for HIV-1 replication in activated CD4 + T cells in vitro and in vivo
    • 10 other authors
    • Kawano, Y., Tanaka, Y., Misawa, N. & 10 other authors (1997). Mutational analysis of human immunodeficiency virus type 1 (HIV-1) accessory genes: requirement of a site in the nef gene for HIV-1 replication in activated CD4 + T cells in vitro and in vivo. J Virol 71, 8456-8466.
    • (1997) J. Virol. , vol.71 , pp. 8456-8466
    • Kawano, Y.1    Tanaka, Y.2    Misawa, N.3
  • 32
  • 33
    • 0031777959 scopus 로고    scopus 로고
    • Role of the SH3-ligand domain of simian immunodeficiency virus Nef in interaction with Net-associated kinase and simian AIDS in rhesus macaques
    • Khan, I. H., Sawai, E. T., Antonio, E., Weber, C. J., Mandell, C. P., Montbriand, P. & Luciw, P. A. (1998). Role of the SH3-ligand domain of simian immunodeficiency virus Nef in interaction with Net-associated kinase and simian AIDS in rhesus macaques. J Virol 72, 5820-5830.
    • (1998) J. Virol. , vol.72 , pp. 5820-5830
    • Khan, I.H.1    Sawai, E.T.2    Antonio, E.3    Weber, C.J.4    Mandell, C.P.5    Montbriand, P.6    Luciw, P.A.7
  • 34
    • 0026562720 scopus 로고
    • Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitve cell line on the basis of activation of an integrated beta-galactosidase gene
    • Kimpton, J. & Emerman, M. (1992). Detection of replication-competent and pseudotyped human immunodeficiency virus with a sensitve cell line on the basis of activation of an integrated beta-galactosidase gene. J Virol 66, 2232-2239.
    • (1992) J. Virol. , vol.66 , pp. 2232-2239
    • Kimpton, J.1    Emerman, M.2
  • 35
    • 0028835788 scopus 로고
    • Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection
    • Kirchhoff, F., Geenough, T. C., Brettler, D. B., Sullivan, J. L. & Desrosiers, R. C. (1995). Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection. N Engl J Med 332, 228-232.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 228-232
    • Kirchhoff, F.1    Geenough, T.C.2    Brettler, D.B.3    Sullivan, J.L.4    Desrosiers, R.C.5
  • 36
    • 0033578072 scopus 로고    scopus 로고
    • Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Environ incorporation in a Nef- and Vpu-inhibitable manner
    • Lama, J., Mangasarian, A. & Trono, D. (1999). Cell-surface expression of CD4 reduces HIV-1 infectivity by blocking Environ incorporation in a Nef- and Vpu-inhibitable manner. Curr Biol 9, 622-631.
    • (1999) Curr. Biol. , vol.9 , pp. 622-631
    • Lama, J.1    Mangasarian, A.2    Trono, D.3
  • 37
    • 0030836543 scopus 로고    scopus 로고
    • Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques
    • 7 other authors
    • Lang, S. M., Iafrate, A. J., Stahl-Henning, C. & 7 other authors (1997). Association of simian immunodeficiency virus Nef with cellular serine/threonine kinases is dispensable for the development of AIDS in rhesus macaques. Nat Med 3, 860-865.
    • (1997) Nat. Med. , vol.3 , pp. 860-865
    • Lang, S.M.1    Iafrate, A.J.2    Stahl-Henning, C.3
  • 38
    • 0033519616 scopus 로고    scopus 로고
    • Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1
    • 9 other authors
    • Learmont, J. C., Geczy, A. F., Mills, J. & 9 other authors (1999). Immunologic and virologic status after 14 to 18 years of infection with an attenuated strain of HIV-1. N Engl J Med 340, 1715-1722.
    • (1999) N. Engl. J. Med. , vol.340 , pp. 1715-1722
    • Learmont, J.C.1    Geczy, A.F.2    Mills, J.3
  • 39
    • 0028805516 scopus 로고
    • A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein
    • Lee, C.-H., Leung, B., Lemmon, M. A., Zheng, J., Cowburn, D., Kuriyan, J. & Saksela, K. (1995). A single amino acid in the SH3 domain of Hck determines its high affinity and specificity in binding to HIV-1 Nef protein. EMBO J 14, 5006-5015.
    • (1995) EMBO. J. , vol.14 , pp. 5006-5015
    • Lee, C.-H.1    Leung, B.2    Lemmon, M.A.3    Zheng, J.4    Cowburn, D.5    Kuriyan, J.6    Saksela, K.7
  • 40
    • 0036231461 scopus 로고    scopus 로고
    • Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes
    • Lundquist, C. A., Tobiume, M., Zhou, J., Unutmaz, D. & Aiken, C. (2002). Nef-mediated downregulation of CD4 enhances human immunodeficiency virus type 1 replication in primary T lymphocytes. J Virol 76, 4625-4633.
    • (2002) J. Virol. , vol.76 , pp. 4625-4633
    • Lundquist, C.A.1    Tobiume, M.2    Zhou, J.3    Unutmaz, D.4    Aiken, C.5
  • 41
    • 0032566903 scopus 로고    scopus 로고
    • SH3-domain binding function of HIV-1 Nef is required for association with PAK-related kinase
    • Manninen, A., Hiipakkam, M., Vihinen, M., Lu, W., Mayer, B. J. & Saksela, K. (1998). SH3-domain binding function of HIV-1 Nef is required for association with PAK-related kinase. Virology 250, 273-282.
    • (1998) Virology , vol.250 , pp. 273-282
    • Manninen, A.1    Hiipakkam, M.2    Vihinen, M.3    Lu, W.4    Mayer, B.J.5    Saksela, K.6
  • 42
    • 0034755158 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 entry into macrophages mediated by macropinocytosis
    • Marechal, V., Prevost, M.-C., Petit, C., Perret, E., Heard, J.-M. & Schwartz, O. (2001). Human immunodeficiency virus type 1 entry into macrophages mediated by macropinocytosis. J Virol 75, 11166-11177.
    • (2001) J. Virol. , vol.75 , pp. 11166-11177
    • Marechal, V.1    Prevost, M.-C.2    Petit, C.3    Perret, E.4    Heard, J.-M.5    Schwartz, O.6
  • 43
    • 0142137243 scopus 로고    scopus 로고
    • HIV's great escape
    • Marsh, M. & Thali, M. (2003). HIV's great escape. Nat Med 9, 1262-1263.
    • (2003) Nat. Med. , vol.9 , pp. 1262-1263
    • Marsh, M.1    Thali, M.2
  • 44
    • 0025003118 scopus 로고
    • Macrophages as susceptible targets for HIV infection, persistent viral reservoirs in tissue, and key immunoregulatory cells that control levels of virus replication and extent of disease
    • Meltzer, M. S., Nakamura, M., Hansen, B. D., Turpin, J. A., Kalter, D. C. & Gendelman, H. E. (1990). Macrophages as susceptible targets for HIV infection, persistent viral reservoirs in tissue, and key immunoregulatory cells that control levels of virus replication and extent of disease. AIDS Res Hum Retrovir 6, 967-971.
    • (1990) AIDS Res. Hum. Retrovir. , vol.6 , pp. 967-971
    • Meltzer, M.S.1    Nakamura, M.2    Hansen, B.D.3    Turpin, J.A.4    Kalter, D.C.5    Gendelman, H.E.6
  • 45
    • 0028936207 scopus 로고
    • Expression of human immunodeficiency virus type I (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp120 or viral entry
    • Miller, M. D., Warmerdam, M. T., Page, K. A., Feinberg, M. B. & Greene, W. C. (1995). Expression of human immunodeficiency virus type I (HIV-1) nef gene during HIV-1 production increases progeny particle infectivity independently of gp120 or viral entry. J Virol 69, 579-584.
    • (1995) J. Virol. , vol.69 , pp. 579-584
    • Miller, M.D.1    Warmerdam, M.T.2    Page, K.A.3    Feinberg, M.B.4    Greene, W.C.5
  • 46
    • 0347993084 scopus 로고    scopus 로고
    • Evidence that HIV budding in primary macrophages occurs through the exosome release pathway
    • Nguyen, D. G., Booth, A., Gould, S. J. & Hildreth, J. E. K. (2003). Evidence that HIV budding in primary macrophages occurs through the exosome release pathway. J Biol Chem 278, 52347-52354.
    • (2003) J. Biol. Chem. , vol.278 , pp. 52347-52354
    • Nguyen, D.G.1    Booth, A.2    Gould, J.3    Hildreth, J.E.K.4
  • 47
    • 0029793714 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Nef associates with a member of the p21-activated kinase family
    • Nunn, M. F. & Marsh, J. W. (1996). Human immunodeficiency virus type 1 Nef associates with a member of the p21-activated kinase family. J Virol 70, 6157-6161.
    • (1996) J. Virol. , vol.70 , pp. 6157-6161
    • Nunn, M.F.1    Marsh, J.W.2
  • 48
    • 0023678515 scopus 로고
    • Cytoplasmic assembly and accumulation of human immunodeficiencyvirus types 1 and 2 in recombinant human colony-stimulating factor-1-treated human monocytes: An ultrastructural study
    • Orenstein, J. M., Meltzer, M. S., Phipps, T. & Gendelman, H. E. (1988). Cytoplasmic assembly and accumulation of human immunodeficiencyvirus types 1 and 2 in recombinant human colony-stimulating factor-1-treated human monocytes: an ultrastructural study. J Virol 62, 2578-2586.
    • (1988) J. Virol. , vol.62 , pp. 2578-2586
    • Orenstein, J.M.1    Meltzer, M.S.2    Phipps, T.3    Gendelman, H.E.4
  • 49
    • 0030860537 scopus 로고    scopus 로고
    • Macrophages as a source of HIV during opportunistic infections
    • Orenstein, J. M., Fox, C. & Wahl, S. M. (1997). Macrophages as a source of HIV during opportunistic infections. Science 276, 1857-1861.
    • (1997) Science , vol.276 , pp. 1857-1861
    • Orenstein, J.M.1    Fox, C.2    Wahl, S.M.3
  • 50
    • 0036319189 scopus 로고    scopus 로고
    • Nef enhances human immunodeficiency virus type 1 infectivity and replication independently of viral coreceptor tropism
    • Papkalla, A., Munch, J., Otto, C. & Kirchhoff, F. (2002). Nef enhances human immunodeficiency virus type 1 infectivity and replication independently of viral coreceptor tropism. J Virol 76, 8455-8459.
    • (2002) J. Virol. , vol.76 , pp. 8455-8459
    • Papkalla, A.1    Munch, J.2    Otto, C.3    Kirchhoff, F.4
  • 51
    • 0041488655 scopus 로고    scopus 로고
    • Infectious HIV-1 assembles in late endosomes in primary macrophages
    • Pelchen-Matthews, A., Kramer, B. & Marsh, M. (2003). Infectious HIV-1 assembles in late endosomes in primary macrophages. J Cell Biol 162, 443-455.
    • (2003) J. Cell Biol. , vol.162 , pp. 443-455
    • Pelchen-Matthews, A.1    Kramer, B.2    Marsh, M.3
  • 52
    • 0033515427 scopus 로고    scopus 로고
    • Nef-induced CD4 degradation: A diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of β -COP in endosomes
    • Piguet, V., Gu, F., Foti, M., Demaurex, N., Gruenberg, J., Carpentier, J.-L. & Trono, D. (1999). Nef-induced CD4 degradation: a diacidic-based motif in Nef functions as a lysosomal targeting signal through the binding of β-COP in endosomes. Cell 97, 63-73.
    • (1999) Cell , vol.97 , pp. 63-73
    • Piguet, V.1    Gu, F.2    Foti, M.3    Demaurex, N.4    Gruenberg, J.5    Carpentier, J.-L.6    Trono, D.7
  • 55
    • 0034134113 scopus 로고    scopus 로고
    • Interactions of HIV-1 NEF with cellular signal transducing proteins
    • Renkema, G. H. & Saksela, K. (2000). Interactions of HIV-1 NEF with cellular signal transducing proteins. Front Biosci 5, D268-283.
    • (2000) Front. Biosci. , vol.5
    • Renkema, G.H.1    Saksela, K.2
  • 56
    • 0033578016 scopus 로고    scopus 로고
    • Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein
    • Ross, T., Oran, A. & Cullen, B. (1999). Inhibition of HIV-1 progeny virion release by cell-surface CD4 is relieved by expression of the viral Nef protein. Curr Biol 9, 613-621.
    • (1999) Curr. Biol. , vol.9 , pp. 613-621
    • Ross, T.1    Oran, A.2    Cullen, B.3
  • 59
    • 0029064101 scopus 로고
    • A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinase activity
    • Sawai, E., Baur, A. S., Peterlin, B. M., Levy, J. A. & Cheng-Mayer, C. (1995). A conserved domain and membrane targeting of Nef from HIV and SIV are required for association with a cellular serine kinase activity. J Biol Chem 270, 15307-15314.
    • (1995) J. Biol. Chem. , vol.270 , pp. 15307-15314
    • Sawai, E.1    Baur, A.S.2    Peterlin, B.M.3    Levy, J.A.4    Cheng-Mayer, C.5
  • 60
    • 0029045360 scopus 로고
    • Human immunodeficiency virus type 1 Nef increases the efficiency of reverse transcription in the infected cell
    • Schwartz, O., Marechal, V., Danos, O. & Heard, J.-M. (1995). Human immunodeficiency virus type 1 Nef increases the efficiency of reverse transcription in the infected cell. J Virol 69, 4053-4059.
    • (1995) J. Virol. , vol.69 , pp. 4053-4059
    • Schwartz, O.1    Marechal, V.2    Danos, O.3    Heard, J.-M.4
  • 62
    • 0034948709 scopus 로고    scopus 로고
    • Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators
    • Simmons, A., Aluvihare, V. & McMichael, A. (2001). Nef triggers a transcriptional program in T cells imitating single-signal T cell activation and inducing HIV virulence mediators. Immunity 14, 763-777.
    • (2001) Immunity , vol.14 , pp. 763-777
    • Simmons, A.1    Aluvihare, V.2    McMichael, A.3
  • 63
    • 0027533215 scopus 로고
    • Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene
    • Skowronski, J., Parks, D. & Mariani, R. (1993). Altered T cell activation and development in transgenic mice expressing the HIV-1 nef gene. EMBO J 12, 703-713.
    • (1993) EMBO J. , vol.12 , pp. 703-713
    • Skowronski, J.1    Parks, D.2    Mariani, R.3
  • 64
    • 0029953176 scopus 로고    scopus 로고
    • The HIV Nef protein associates with protein kinase C theta
    • Smith, B. L., Krushelnycky, B. W., Mochly, R. D. & Berg, P. (1996). The HIV Nef protein associates with protein kinase C theta. J Biol Chem 271, 16753-16757.
    • (1996) J. Biol. Chem. , vol.271 , pp. 16753-16757
    • Smith, B.L.1    Krushelnycky, B.W.2    Mochly, R.D.3    Berg, P.4
  • 65
    • 0037302331 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Nef-mediated downregulation of CD4 correlates with Nef enhancement of viral pathogenesis
    • 8 other authors
    • Stoddart, C. A., Geleziunas, R., Ferrell, S. & 8 other authors (2003). Human immunodeficiency virus type 1 Nef-mediated downregulation of CD4 correlates with Nef enhancement of viral pathogenesis. J Virol 77, 2124-2133.
    • (2003) J. Virol. , vol.77 , pp. 2124-2133
    • Stoddart, C.A.1    Geleziunas, R.2    Ferrell, S.3
  • 66
    • 0037333915 scopus 로고    scopus 로고
    • Potential role for CD63 in CCR5-mediated human immunodeficiency virus type 1 infection of macrophages
    • 9 other authors
    • von Lindern, J. J., Rojo, D., Grovit-Ferbas, K. & 9 other authors (2003). Potential role for CD63 in CCR5-mediated human immunodeficiency virus type 1 infection of macrophages. J Virol 77, 3624-3633.
    • (2003) J. Virol. , vol.77 , pp. 3624-3633
    • von Lindern, J.J.1    Rojo, D.2    Grovit-Ferbas, K.3
  • 67
    • 0030273317 scopus 로고    scopus 로고
    • HIV-1 Nef association with cellular serine kinase correlates with enhanced virion infectivity and efficient proviral DNA synthesis
    • Wiskerchen, M. & Cheng-Mayer, C. (1996). HIV-1 Nef association with cellular serine kinase correlates with enhanced virion infectivity and efficient proviral DNA synthesis. Virology 224, 292-301.
    • (1996) Virology , vol.224 , pp. 292-301
    • Wiskerchen, M.1    Cheng-Mayer, C.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.