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Volumn 83, Issue 22, 2009, Pages 11528-11539

Inhibition of T-cell receptor-induced actin remodeling and relocalization of Lck are evolutionarily conserved activities of lentiviral Nef proteins

Author keywords

[No Author keywords available]

Indexed keywords

CD3 ANTIBODY; CELL SURFACE PROTEIN; F ACTIN; NEF PROTEIN; PROTEIN KINASE LCK; T LYMPHOCYTE RECEPTOR;

EID: 70350312836     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.01423-09     Document Type: Article
Times cited : (40)

References (42)
  • 1
    • 0031791917 scopus 로고    scopus 로고
    • Association of simian immunodeficiency virus Nef with the T-cell receptor (TCR) zeta chain leads to TCR downmodulation
    • Bell, I., C. Ashman, J. Maughan, E. Hooker, F. Cook, and T. A. Reinhart. 1998. Association of simian immunodeficiency virus Nef with the T-cell receptor (TCR) zeta chain leads to TCR downmodulation. J. Gen. Virol. 79(Pt. 11):2717-2727.
    • (1998) J. Gen. Virol. , vol.79 , Issue.PART. 11 , pp. 2717-2727
    • Bell, I.1    Ashman, C.2    Maughan, J.3    Hooker, E.4    Cook, F.5    Reinhart, T.A.6
  • 2
    • 33846626054 scopus 로고    scopus 로고
    • Regulation of T-cell activation by the cytoskeleton
    • Billadeau, D. D., J. C. Nolz, and T. S. Gomez. 2007. Regulation of T-cell activation by the cytoskeleton. Nat. Rev. Immunol. 7:131-143.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 131-143
    • Billadeau, D.D.1    Nolz, J.C.2    Gomez, T.S.3
  • 3
    • 0035075507 scopus 로고    scopus 로고
    • Dynamic actin polymerization drives T-cell receptor-induced spreading: A role for the signal transduction adaptor LAT
    • Bunnell, S. C., V. Kapoor, R. P. Trible, W. Zhang, and L. E. Samelson. 2001. Dynamic actin polymerization drives T-cell receptor-induced spreading: a role for the signal transduction adaptor LAT. Immunity 14:315-329.
    • (2001) Immunity , vol.14 , pp. 315-329
    • Bunnell, S.C.1    Kapoor, V.2    Trible, R.P.3    Zhang, W.4    Samelson, L.E.5
  • 4
    • 27544441784 scopus 로고    scopus 로고
    • Actin and agonist MHCpeptide complex-dependent T-cell receptor microclusters as scaffolds for signaling
    • Campi, G., R. Varma, and M. L. Dustin. 2005. Actin and agonist MHCpeptide complex-dependent T-cell receptor microclusters as scaffolds for signaling. J. Exp. Med. 202:1031-1036.
    • (2005) J. Exp. Med. , vol.202 , pp. 1031-1036
    • Campi, G.1    Varma, R.2    Dustin, M.L.3
  • 5
    • 0029874657 scopus 로고    scopus 로고
    • T-cell antigen receptor signal transduction pathways
    • Cantrell, D. 1996. T-cell antigen receptor signal transduction pathways. Annu. Rev. Immunol. 14:259-274.
    • (1996) Annu. Rev. Immunol. , vol.14 , pp. 259-274
    • Cantrell, D.1
  • 6
    • 0025181117 scopus 로고
    • Residues of the variable region of the T-cell-receptor beta-chain that interact with Staphylococcus aureus toxin superantigens
    • Choi, Y. W., A. Herman, D. DiGiusto, T. Wade, P. Marrack, and J. Kappler. 1990. Residues of the variable region of the T-cell-receptor beta-chain that interact with Staphylococcus aureus toxin superantigens. Nature 346:471-473.
    • (1990) Nature , vol.346 , pp. 471-473
    • Choi, Y.W.1    Herman, A.2    Digiusto, D.3    Wade, T.4    Marrack, P.5    Kappler, J.6
  • 7
    • 2442511061 scopus 로고    scopus 로고
    • Activation-induced polarized recycling targets T cell antigen receptors to the immunological synapse: Involvement of SNARE complexes
    • DOI 10.1016/S1074-7613(04)00106-2, PII S1074761304001062
    • Das, V., B. Nal, A. Dujeancourt, M. I. Thoulouze, T. Galli, P. Roux, A. Dautry-Varsat, and A. Alcover. 2004. Activation-induced polarized recycling targets T-cell antigen receptors to the immunological synapse; involvement of SNARE complexes. Immunity 20:577-588. (Pubitemid 38638127)
    • (2004) Immunity , vol.20 , Issue.5 , pp. 577-588
    • Das, V.1    Nal, B.2    Dujeancourt, A.3    Thoulouze, M.-I.4    Galli, T.5    Roux, P.6    Dautry-Varsat, A.7    Alcover, A.8
  • 9
    • 33947591273 scopus 로고    scopus 로고
    • Modulation of the immunological synapse: A key to HIV-1 pathogenesis?
    • Fackler, O. T., A. Alcover, and O. Schwartz. 2007. Modulation of the immunological synapse: a key to HIV-1 pathogenesis? Nat. Rev. Immunol. 7:310-317.
    • (2007) Nat. Rev. Immunol. , vol.7 , pp. 310-317
    • Fackler, O.T.1    Alcover, A.2    Schwartz, O.3
  • 10
    • 0036230879 scopus 로고    scopus 로고
    • Live and let die: Nef functions beyond HIV replication
    • Fackler, O. T., and A. S. Baur. 2002. Live and let die: Nef functions beyond HIV replication. Immunity 16:493-497.
    • (2002) Immunity , vol.16 , pp. 493-497
    • Fackler, O.T.1    Baur, A.S.2
  • 12
    • 27144505682 scopus 로고    scopus 로고
    • Nef is physically recruited into the immunological synapse and potentiates T cell activation early after TCR engagement
    • Fenard, D., W. Yonemoto, C. de Noronha, M. Cavrois, S. A. Williams, and W. C. Greene. 2005. Nef is physically recruited into the immunological synapse and potentiates T-cell activation early after TCR engagement. J. Immunol. 175:6050-6057. (Pubitemid 41508091)
    • (2005) Journal of Immunology , vol.175 , Issue.9 , pp. 6050-6057
    • Fenard, D.1    Yonemoto, W.2    De Noronha, C.3    Cavrois, M.4    Williams, S.A.5    Greene, W.C.6
  • 13
    • 4544288671 scopus 로고    scopus 로고
    • + T cells requires Nef and Tat virus gene products and results from higher NFAT, NF- B, and AP-1 induction
    • + T cells requires Nef and Tat virus gene products and results from higher NFAT, NF- B, and AP-1 induction. J. Biol. Chem. 279:39520-39531.
    • (2004) J. Biol. Chem. , vol.279 , pp. 39520-39531
    • Fortin, J.F.1    Barat, C.2    Beausejour, Y.3    Barbeau, B.4    Tremblay, M.J.5
  • 14
    • 44049096985 scopus 로고    scopus 로고
    • T-cell activation and the cytoskeleton: You can't have one without the other
    • Gomez, T. S., and D. D. Billadeau. 2008. T-cell activation and the cytoskeleton: you can't have one without the other. Adv. Immunol. 97:1-64.
    • (2008) Adv. Immunol. , vol.97 , pp. 1-64
    • Gomez, T.S.1    Billadeau, D.D.2
  • 15
    • 33847311403 scopus 로고    scopus 로고
    • Formins regulate the actin-related protein 2/3 complexindependent polarization of the centrosome to the immunological synapse
    • Gomez, T. S., K. Kumar, R. B. Medeiros, Y. Shimizu, P. J. Leibson, and D. D. Billadeau. 2007. Formins regulate the actin-related protein 2/3 complexindependent polarization of the centrosome to the immunological synapse. Immunity 26:177-190.
    • (2007) Immunity , vol.26 , pp. 177-190
    • Gomez, T.S.1    Kumar, K.2    Medeiros, R.B.3    Shimizu, Y.4    Leibson, P.J.5    Billadeau, D.D.6
  • 17
    • 0033538574 scopus 로고    scopus 로고
    • The immunological synapse: A molecular machine controlling T cell activation
    • DOI 10.1126/science.285.5425.221
    • Grakoui, A., S. K. Bromley, C. Sumen, M. M. Davis, A. S. Shaw, P. M. Allen, and M. L. Dustin. 1999. The immunological synapse: a molecular machine controlling T-cell activation. Science 285:221-227. (Pubitemid 29329988)
    • (1999) Science , vol.285 , Issue.5425 , pp. 221-227
    • Grakoui, A.1    Bromley, S.K.2    Sumen, C.3    Davis, M.M.4    Shaw, A.S.5    Allen, P.M.6    Dustin, M.L.7
  • 18
    • 54049135185 scopus 로고    scopus 로고
    • HIV-1 at the immunological and Tlymphocytic virological synapse
    • Haller, C., and O. T. Fackler. 2008. HIV-1 at the immunological and Tlymphocytic virological synapse. Biol. Chem. 389:1253-1260.
    • (2008) Biol. Chem. , vol.389 , pp. 1253-1260
    • Haller, C.1    Fackler, O.T.2
  • 19
    • 43249085765 scopus 로고    scopus 로고
    • HIV-1 Nef employs two distinct mechanisms to modulate Lck subcellular localization and TCR induced actin remodeling
    • DOI 10.1371/journal.pone.0001212
    • Haller, C., S. Rauch, and O. T. Fackler. 2007. HIV-1 Nef employs two distinct mechanisms to modulate Lck subcellular localization and TCR induced actin remodeling. PLoS ONE 2:e1212. (Pubitemid 351649977)
    • (2007) PLoS ONE , vol.2 , Issue.11
    • Haller, C.1    Rauch, S.2    Fackler, O.T.3
  • 20
    • 33745835407 scopus 로고    scopus 로고
    • The HIV-1 pathogenicity factor Nef interferes with maturation of stimulatory T-lymphocyte contacts by modulation of N-Wasp activity
    • Haller, C., S. Rauch, N. Michel, S. Hannemann, M. J. Lehmann, O. T. Keppler, and O. T. Fackler. 2006. The HIV-1 pathogenicity factor Nef interferes with maturation of stimulatory T-lymphocyte contacts by modulation of N-Wasp activity. J. Biol. Chem. 281:19618-19630.
    • (2006) J. Biol. Chem. , vol.281 , pp. 19618-19630
    • Haller, C.1    Rauch, S.2    Michel, N.3    Hannemann, S.4    Lehmann, M.J.5    Keppler, O.T.6    Fackler, O.T.7
  • 21
    • 0032538278 scopus 로고    scopus 로고
    • Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice
    • DOI 10.1016/S0092-8674(00)81748-1
    • Hanna, Z., D. G. Kay, N. Rebai, A. Guimond, S. Jothy, and P. Jolicoeur. 1998. Nef harbors a major determinant of pathogenicity for an AIDS-like disease induced by HIV-1 in transgenic mice. Cell 95:163-175. (Pubitemid 28473778)
    • (1998) Cell , vol.95 , Issue.2 , pp. 163-175
    • Hanna, Z.1    Kay, D.G.2    Rebai, N.3    Guimond, A.4    Jothy, S.5    Jolicoeur, P.6
  • 22
    • 34548012864 scopus 로고    scopus 로고
    • Plasma membrane segregation during T-cell activation: Probing the order of domains
    • Harder, T., C. Rentero, T. Zech, and K. Gaus. 2007. Plasma membrane segregation during T-cell activation: probing the order of domains. Curr. Opin. Immunol. 19:470-475.
    • (2007) Curr. Opin. Immunol. , vol.19 , pp. 470-475
    • Harder, T.1    Rentero, C.2    Zech, T.3    Gaus, K.4
  • 23
    • 0031774858 scopus 로고    scopus 로고
    • Zeta chain of the T-cell receptor interacts with nef of simian immunodeficiency virus and human immunodeficiency virus type 2
    • Howe, A. Y., J. U. Jung, and R. C. Desrosiers. 1998. Zeta chain of the T-cell receptor interacts with nef of simian immunodeficiency virus and human immunodeficiency virus type 2. J. Virol. 72:9827-9834. (Pubitemid 28520848)
    • (1998) Journal of Virology , vol.72 , Issue.12 , pp. 9827-9834
    • Howe, A.Y.M.1    Jung, J.U.2    Desrosiers, R.C.3
  • 24
    • 34047117842 scopus 로고    scopus 로고
    • T-cell-receptor-dependent actin regulatory mechanisms
    • Huang, Y., and J. K. Burkhardt. 2007. T-cell-receptor-dependent actin regulatory mechanisms. J. Cell Sci. 120:723-730.
    • (2007) J. Cell Sci. , vol.120 , pp. 723-730
    • Huang, Y.1    Burkhardt, J.K.2
  • 25
    • 0031039979 scopus 로고    scopus 로고
    • Separable functions of Nef disrupt two aspects of T-cell receptor machinery: CD4 expression and CD3 signaling
    • Iafrate, A. J., S. Bronson, and J. Skowronski. 1997. Separable functions of Nef disrupt two aspects of T-cell receptor machinery: CD4 expression and CD3 signaling. EMBO J. 16:673-684.
    • (1997) EMBO J. , vol.16 , pp. 673-684
    • Iafrate, A.J.1    Bronson, S.2    Skowronski, J.3
  • 26
    • 67349114397 scopus 로고    scopus 로고
    • T-cell antigen receptor signaling and immunological synapse stability require myosin IIA
    • Ilani, T., G. Vasiliver-Shamis, S. Vardhana, A. Bretscher, and M. L. Dustin. 2009. T-cell antigen receptor signaling and immunological synapse stability require myosin IIA. Nat. Immunol. 10:531-539.
    • (2009) Nat. Immunol. , vol.10 , pp. 531-539
    • Ilani, T.1    Vasiliver-Shamis, G.2    Vardhana, S.3    Bretscher, A.4    Dustin, M.L.5
  • 28
    • 67349166158 scopus 로고    scopus 로고
    • Is the high virulence of HIV-1 an unfortunate coincidence of primate lentiviral evolution?
    • Kirchhoff, F. 2009. Is the high virulence of HIV-1 an unfortunate coincidence of primate lentiviral evolution? Nat. Rev. Microbiol. 7:467-476.
    • (2009) Nat. Rev. Microbiol. , vol.7 , pp. 467-476
    • Kirchhoff, F.1
  • 29
    • 0028835788 scopus 로고
    • Brief report: Absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection
    • Kirchhoff, F., T. C. Greenough, D. B. Brettler, J. L. Sullivan, and R. C. Desrosiers. 1995. Brief report: absence of intact nef sequences in a long-term survivor with nonprogressive HIV-1 infection. N. Engl. J. Med. 332:228-232.
    • (1995) N. Engl. J. Med. , vol.332 , pp. 228-232
    • Kirchhoff, F.1    Greenough, T.C.2    Brettler, D.B.3    Sullivan, J.L.4    Desrosiers, R.C.5
  • 30
    • 44649139364 scopus 로고    scopus 로고
    • HIV-1 accessory proteins-ensuring viral survival in a hostile environment
    • Malim, M. H., and M. Emerman. 2008. HIV-1 accessory proteins-ensuring viral survival in a hostile environment. Cell Host Microbe 3:388-398.
    • (2008) Cell Host Microbe , vol.3 , pp. 388-398
    • Malim, M.H.1    Emerman, M.2
  • 31
    • 23244465720 scopus 로고    scopus 로고
    • Primary sooty mangabey simian immunodeficiency virus and human immunodeficiency virus type 2 nef alleles modulate cell surface expression of various human receptors and enhance viral infectivity and replication
    • Munch, J., M. Schindler, S. Wildum, E. Rucker, N. Bailer, V. Knoop, F. J. Novembre, and F. Kirchhoff. 2005. Primary sooty mangabey simian immunodeficiency virus and human immunodeficiency virus type 2 nef alleles modulate cell surface expression of various human receptors and enhance viral infectivity and replication. J. Virol. 79:10547-10560.
    • (2005) J. Virol. , vol.79 , pp. 10547-10560
    • Munch, J.1    Schindler, M.2    Wildum, S.3    Rucker, E.4    Bailer, N.5    Knoop, V.6    Novembre, F.J.7    Kirchhoff, F.8
  • 33
    • 31144476786 scopus 로고    scopus 로고
    • Dynamic evolution of the human immunodeficiency virus type 1 pathogenic factor, Nef
    • DOI 10.1128/JVI.80.3.1311-1320.2006
    • O'Neill, E., L. S. Kuo, J. F. Krisko, D. R. Tomchick, J. V. Garcia, and J. L. Foster. 2006. Dynamic evolution of the human immunodeficiency virus type 1 pathogenic factor, Nef. J. Virol. 80:1311-1320. (Pubitemid 43134088)
    • (2006) Journal of Virology , vol.80 , Issue.3 , pp. 1311-1320
    • O'Neill, E.1    Kuo, L.S.2    Krisko, J.F.3    Tomchick, D.R.4    Garcia, J.V.5    Foster, J.L.6
  • 34
    • 40149097137 scopus 로고    scopus 로고
    • Human immunodeficiency virus type 1 Nef recruits the guanine exchange factor Vav1 via an unexpected interface into plasma membrane microdomains for association with p21-activated kinase 2 activity
    • DOI 10.1128/JVI.02185-07
    • Rauch, S., K. Pulkkinen, K. Saksela, and O. T. Fackler. 2008. Human immunodeficiency virus type 1 Nef recruits the guanine exchange factor Vav1 via an unexpected interface into plasma membrane microdomains for association with p21-activated kinase 2 activity. J. Virol. 82:2918-2929. (Pubitemid 351329181)
    • (2008) Journal of Virology , vol.82 , Issue.6 , pp. 2918-2929
    • Rauch, S.1    Pulkkinen, K.2    Saksela, K.3    Fackler, O.T.4
  • 35
    • 33646137152 scopus 로고    scopus 로고
    • Immunological synapse and microclusters: The site for recognition and activation of T cells
    • Saito, T., and T. Yokosuka. 2006. Immunological synapse and microclusters: the site for recognition and activation of T cells. Curr. Opin. Immunol. 18:305-313.
    • (2006) Curr. Opin. Immunol. , vol.18 , pp. 305-313
    • Saito, T.1    Yokosuka, T.2
  • 38
    • 0033529258 scopus 로고    scopus 로고
    • HIV-1 Nef increases T-cell activation in a stimulus-dependent manner
    • Schrager, J. A., and J. W. Marsh. 1999. HIV-1 Nef increases T-cell activation in a stimulus-dependent manner. Proc. Natl. Acad. Sci. USA 96:8167-8172.
    • (1999) Proc. Natl. Acad. Sci. USA , vol.96 , pp. 8167-8172
    • Schrager, J.A.1    Marsh, J.W.2
  • 39
    • 3543091246 scopus 로고    scopus 로고
    • Interplay between TCR signalling and actin cytoskeleton dynamics
    • DOI 10.1016/j.it.2004.03.003, PII S1471490604000900
    • Sechi, A. S., and J. Wehland. 2004. Interplay between TCR signalling and actin cytoskeleton dynamics. Trends Immunol. 25:257-265. (Pubitemid 38501672)
    • (2004) Trends in Immunology , vol.25 , Issue.5 , pp. 257-265
    • Sechi, A.S.1    Wehland, J.2
  • 41
    • 33646552033 scopus 로고    scopus 로고
    • Human Immunodeficiency Virus Type-1 Infection Impairs the Formation of the Immunological Synapse
    • DOI 10.1016/j.immuni.2006.02.016, PII S1074761306002196
    • Thoulouze, M. I., N. Sol-Foulon, F. Blanchet, A. Dautry-Varsat, O. Schwartz, and A. Alcover. 2006. Human immunodeficiency virus type-1 infection impairs the formation of the immunological synapse. Immunity 24:547-561. (Pubitemid 43728159)
    • (2006) Immunity , vol.24 , Issue.5 , pp. 547-561
    • Thoulouze, M.I.1    Sol-Foulon, N.2    Blanchet, F.3    Dautry-Varsat, A.4    Schwartz, O.5    Alcover, A.6
  • 42
    • 0028961573 scopus 로고
    • Sustained signaling leading to T-cell activation results from prolonged T-cell receptor occupancy: Role of T-cell actin cytoskeleton
    • Valitutti, S., M. Dessing, K. Aktories, H. Gallati, and A. Lanzavecchia. 1995. Sustained signaling leading to T-cell activation results from prolonged T-cell receptor occupancy: role of T-cell actin cytoskeleton. J. Exp. Med. 181:577-584.
    • (1995) J. Exp. Med. , vol.181 , pp. 577-584
    • Valitutti, S.1    Dessing, M.2    Aktories, K.3    Gallati, H.4    Lanzavecchia, A.5


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