The inability to disrupt the immunological synapse between infected human T cells and APCs distinguishes HIV-1 from most other primate lentiviruses

Journal of Clinical Investigation

Volumn 119, Issue 10, 2009, Pages 2965-2975

  Arhel, Nathalie ^a   Lehmann, Martin ^b   Clauß, Karen ^a   Nienhaus, G Ulrich ^a,c   Piguet, Vincent ^b   Kirchhoff, Frank ^a  

^a UNIVERSITY OF ULM   (Germany)

^b GENEVA UNIVERSITY HOSPITALS   (Switzerland)

^c UNIVERSITY OF KARLSRUHE   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CD28 ANTIGEN; CD3 ANTIGEN; NEF PROTEIN; T LYMPHOCYTE RECEPTOR;

ANTIGEN PRESENTING CELL; ARTICLE; CD4+ T LYMPHOCYTE; CELL SURFACE; CONTROLLED STUDY; DENDRITIC CELL; DOWN REGULATION; HUMAN; HUMAN CELL; HUMAN IMMUNODEFICIENCY VIRUS 1; HUMAN IMMUNODEFICIENCY VIRUS 1 INFECTION; HUMAN IMMUNODEFICIENCY VIRUS 2; IMMUNOLOGICAL SYNAPSE; MACROPHAGE; NONHUMAN; PRIORITY JOURNAL; SIGNAL TRANSDUCTION; SIMIAN IMMUNODEFICIENCY VIRUS; SYNAPSE; VIRUS GENE;

ALLELES; ANIMALS; ANTIGEN-PRESENTING CELLS; ANTIGENS, CD3; CELLS, CULTURED; COCULTURE TECHNIQUES; HIV-1; HUMANS; IMMUNOLOGICAL SYNAPSES; LENTIVIRUSES, PRIMATE; LYMPHOCYTE FUNCTION-ASSOCIATED ANTIGEN-1; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); NEF GENE PRODUCTS, HUMAN IMMUNODEFICIENCY VIRUS; PRIMATES; RECEPTORS, ANTIGEN, T-CELL; T-LYMPHOCYTES; TALIN;

EID: 70349705617     PISSN: 00219738     EISSN: 15588238     Source Type: Journal    
DOI: 10.1172/JCI38994     Document Type: Article

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