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Volumn 3, Issue 12, 2011, Pages 1142-1153

One size may not fit all: Anti-aging therapies and sarcopenia

Author keywords

Anti aging; Caloric restriction; Caloric restriction mimetics; Sarcopenia; Skeletal muscle; Therapy

Indexed keywords


EID: 84859514751     PISSN: 19454589     EISSN: None     Source Type: Journal    
DOI: 10.18632/aging.100409     Document Type: Article
Times cited : (27)

References (138)
  • 1
    • 0028280541 scopus 로고
    • Skeletal muscle weakness in old age: underlying mechanisms
    • Brooks SV, Faulkner JA. Skeletal muscle weakness in old age: underlying mechanisms. Med Sci Sports Exerc. 1994; 26:432-439.
    • (1994) Med Sci Sports Exerc. , vol.26 , pp. 432-439
    • Brooks, S.V.1    Faulkner, J.A.2
  • 2
    • 33744497045 scopus 로고    scopus 로고
    • The roles of satellite cells and hematopoietic stem cells in impaired regeneration of skeletal muscle in old rats
    • Machida S, Narusawa M. The roles of satellite cells and hematopoietic stem cells in impaired regeneration of skeletal muscle in old rats. Ann N Y Acad Sci. 2006; 1067:349-353.
    • (2006) Ann N Y Acad Sci. , vol.1067 , pp. 349-353
    • Machida, S.1    Narusawa, M.2
  • 3
    • 47949097215 scopus 로고    scopus 로고
    • Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells
    • Carlson ME, Hsu M, Conboy IM. Imbalance between pSmad3 and Notch induces CDK inhibitors in old muscle stem cells. Nature. 2008; 454:528-532.
    • (2008) Nature. , vol.454 , pp. 528-532
    • Carlson, M.E.1    Hsu, M.2    Conboy, I.M.3
  • 6
    • 21244496302 scopus 로고    scopus 로고
    • Apoptosis in muscle atrophy: relevance to sarcopenia
    • Dupont-Versteegden EE. Apoptosis in muscle atrophy: relevance to sarcopenia. Exp Gerontol. 2005; 40:473-481.
    • (2005) Exp Gerontol. , vol.40 , pp. 473-481
    • Dupont-Versteegden, E.E.1
  • 9
    • 19044382842 scopus 로고    scopus 로고
    • Reducing falls and resulting hip fractures among older women
    • quiz 140-131
    • Stevens JA, Olson S. Reducing falls and resulting hip fractures among older women. Home Care Provid. 2000; 5:134-139; quiz 140-131.
    • (2000) Home Care Provid , vol.5 , pp. 134-139
    • Stevens, J.A.1    Olson, S.2
  • 10
    • 58149100407 scopus 로고    scopus 로고
    • The ageing immune system: is it ever too old to become young again?
    • Dorshkind K, Montecino-Rodriguez E, Signer RA. The ageing immune system: is it ever too old to become young again? Nat Rev Immunol. 2009; 9:57-62.
    • (2009) Nat Rev Immunol , vol.9 , pp. 57-62
    • Dorshkind, K.1    Montecino-Rodriguez, E.2    Signer, R.A.3
  • 11
    • 0028824981 scopus 로고
    • Strength and aerobic training attenuate muscle wasting and improve resistance to the development of disability with aging
    • Tseng BS, Marsh DR, Hamilton MT, Booth FW. Strength and aerobic training attenuate muscle wasting and improve resistance to the development of disability with aging. J Gerontol A Biol Sci Med Sci. 1995; 50 Spec No:113-119.
    • (1995) J Gerontol A Biol Sci Med Sci , vol.50 , pp. 113-119
    • Tseng, B.S.1    Marsh, D.R.2    Hamilton, M.T.3    Booth, F.W.4
  • 14
    • 0036246979 scopus 로고    scopus 로고
    • Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability
    • Janssen I, Heymsfield SB, Ross R. Low relative skeletal muscle mass (sarcopenia) in older persons is associated with functional impairment and physical disability. J Am Geriatr Soc. 2002; 50:889-896.
    • (2002) J Am Geriatr Soc. , vol.50 , pp. 889-896
    • Janssen, I.1    Heymsfield, S.B.2    Ross, R.3
  • 15
    • 0026051958 scopus 로고
    • Skeletal muscle atrophy in old rats: differential changes in the three fiber types
    • Holloszy JO, Chen M, Cartee GD, Young JC. Skeletal muscle atrophy in old rats: differential changes in the three fiber types. Mech Ageing Dev. 1991; 60:199-213.
    • (1991) Mech Ageing Dev. , vol.60 , pp. 199-213
    • Holloszy, J.O.1    Chen, M.2    Cartee, G.D.3    Young, J.C.4
  • 16
    • 0023856536 scopus 로고
    • What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15-to 83-year-old men
    • Lexell J, Taylor CC, Sjostrom M. What is the cause of the ageing atrophy? Total number, size and proportion of different fiber types studied in whole vastus lateralis muscle from 15-to 83-year-old men. J Neurol Sci. 1988; 84:275-294.
    • (1988) J Neurol Sci. , vol.84 , pp. 275-294
    • Lexell, J.1    Taylor, C.C.2    Sjostrom, M.3
  • 17
    • 0035660803 scopus 로고    scopus 로고
    • Effects of aging on muscle T2 relaxation time: difference between fast-and slow-twitch muscles
    • Hatakenaka M, Ueda M, Ishigami K, Otsuka M, Masuda K. Effects of aging on muscle T2 relaxation time: difference between fast-and slow-twitch muscles. Invest Radiol. 2001; 36:692-698.
    • (2001) Invest Radiol. , vol.36 , pp. 692-698
    • Hatakenaka, M.1    Ueda, M.2    Ishigami, K.3    Otsuka, M.4    Masuda, K.5
  • 18
    • 0030991893 scopus 로고    scopus 로고
    • Decline in isokinetic force with age: muscle cross-sectional area and specific force
    • Jubrias SA, Odderson IR, Esselman PC, Conley KE. Decline in isokinetic force with age: muscle cross-sectional area and specific force. Pflugers Arch. 1997; 434:246-253.
    • (1997) Pflugers Arch. , vol.434 , pp. 246-253
    • Jubrias, S.A.1    Odderson, I.R.2    Esselman, P.C.3    Conley, K.E.4
  • 19
    • 0026453491 scopus 로고
    • Thigh composition in young and elderly men determined by computed tomography
    • Overend TJ, Cunningham DA, Paterson DH, Lefcoe MS. Thigh composition in young and elderly men determined by computed tomography. Clin Physiol. 1992; 12:629-640.
    • (1992) Clin Physiol. , vol.12 , pp. 629-640
    • Overend, T.J.1    Cunningham, D.A.2    Paterson, D.H.3    Lefcoe, M.S.4
  • 20
    • 0024392927 scopus 로고
    • Arm and leg composition determined by computed tomography in young and elderly men
    • Rice CL, Cunningham DA, Paterson DH, Lefcoe MS. Arm and leg composition determined by computed tomography in young and elderly men. Clin Physiol. 1989; 9:207-220.
    • (1989) Clin Physiol. , vol.9 , pp. 207-220
    • Rice, C.L.1    Cunningham, D.A.2    Paterson, D.H.3    Lefcoe, M.S.4
  • 21
    • 0345708253 scopus 로고    scopus 로고
    • Life-long calorie restriction in Fischer 344 rats attenuates age-related loss in skeletal muscle-specific force and reduces extracellular space
    • Payne AM, Dodd SL, Leeuwenburgh C. Life-long calorie restriction in Fischer 344 rats attenuates age-related loss in skeletal muscle-specific force and reduces extracellular space. J Appl Physiol. 2003; 95:2554-2562.
    • (2003) J Appl Physiol. , vol.95 , pp. 2554-2562
    • Payne, A.M.1    Dodd, S.L.2    Leeuwenburgh, C.3
  • 22
    • 3242685274 scopus 로고    scopus 로고
    • Beneficial effects of mild lifelong dietary restriction on skeletal muscle: prevention of age-related mitochondrial damage, morphological changes, and vulnerability to a chemical toxin
    • Usuki F, Yasutake A, Umehara F, Higuchi I. Beneficial effects of mild lifelong dietary restriction on skeletal muscle: prevention of age-related mitochondrial damage, morphological changes, and vulnerability to a chemical toxin. Acta Neuropathol. 2004; 108:1-9.
    • (2004) Acta Neuropathol. , vol.108 , pp. 1-9
    • Usuki, F.1    Yasutake, A.2    Umehara, F.3    Higuchi, I.4
  • 23
    • 0142213542 scopus 로고    scopus 로고
    • The free radical theory of aging
    • Harman D. The free radical theory of aging. Antioxid Redox Signal. 2003; 5:557-561.
    • (2003) Antioxid Redox Signal. , vol.5 , pp. 557-561
    • Harman, D.1
  • 24
    • 33750719067 scopus 로고    scopus 로고
    • Aging: a shift from redox regulation to oxidative damage
    • Humphries KM, Szweda PA, Szweda LI. Aging: a shift from redox regulation to oxidative damage. Free Radic Res. 2006; 40:1239-1243.
    • (2006) Free Radic Res. , vol.40 , pp. 1239-1243
    • Humphries, K.M.1    Szweda, P.A.2    Szweda, L.I.3
  • 25
    • 30044434360 scopus 로고    scopus 로고
    • The mitochondrial theory of aging and its relationship to reactive oxygen species damage and somatic mtDNA mutations
    • Loeb LA, Wallace DC, Martin GM. The mitochondrial theory of aging and its relationship to reactive oxygen species damage and somatic mtDNA mutations. Proc Natl Acad Sci U S A. 2005; 102:18769-18770.
    • (2005) Proc Natl Acad Sci U S A. , vol.102 , pp. 18769-18770
    • Loeb, L.A.1    Wallace, D.C.2    Martin, G.M.3
  • 26
    • 12344335611 scopus 로고    scopus 로고
    • Life long calorie restriction increases heat shock proteins and proteasome activity in soleus muscles of Fisher 344 rats
    • Selsby JT, Judge AR, Yimlamai T, Leeuwenburgh C, Dodd SL. Life long calorie restriction increases heat shock proteins and proteasome activity in soleus muscles of Fisher 344 rats. Exp Gerontol. 2005; 40:37-42.
    • (2005) Exp Gerontol. , vol.40 , pp. 37-42
    • Selsby, J.T.1    Judge, A.R.2    Yimlamai, T.3    Leeuwenburgh, C.4    Dodd, S.L.5
  • 28
    • 75049085555 scopus 로고    scopus 로고
    • Skeletal muscle autophagy and apoptosis during aging: effects of calorie restriction and life-long exercise
    • Wohlgemuth SE, Seo AY, Marzetti E, Lees HA, Leeuwenburgh C. Skeletal muscle autophagy and apoptosis during aging: effects of calorie restriction and life-long exercise. Exp Gerontol. 2010; 45:138-148.
    • (2010) Exp Gerontol. , vol.45 , pp. 138-148
    • Wohlgemuth, S.E.1    Seo, A.Y.2    Marzetti, E.3    Lees, H.A.4    Leeuwenburgh, C.5
  • 30
    • 33845645391 scopus 로고    scopus 로고
    • Synergistic effects of caloric restriction with maintained protein intake on skeletal muscle performance in 21-month-old rats: a mitochondria-mediated pathway
    • Zangarelli A, Chanseaume E, Morio B, Brugere C, Mosoni L, Rousset P, Giraudet C, Patrac V, Gachon P, Boirie Y, Walrand S. Synergistic effects of caloric restriction with maintained protein intake on skeletal muscle performance in 21-month-old rats: a mitochondria-mediated pathway. FASEB J. 2006; 20:2439-2450.
    • (2006) FASEB J. , vol.20 , pp. 2439-2450
    • Zangarelli, A.1    Chanseaume, E.2    Morio, B.3    Brugere, C.4    Mosoni, L.5    Rousset, P.6    Giraudet, C.7    Patrac, V.8    Gachon, P.9    Boirie, Y.10    Walrand, S.11
  • 33
    • 77953531909 scopus 로고    scopus 로고
    • Autophagy inhibition induces atrophy and myopathy in adult skeletal muscles
    • Masiero E, Sandri M. Autophagy inhibition induces atrophy and myopathy in adult skeletal muscles. Autophagy. 2010; 6:307-309.
    • (2010) Autophagy. , vol.6 , pp. 307-309
    • Masiero, E.1    Sandri, M.2
  • 34
  • 35
    • 0347318125 scopus 로고    scopus 로고
    • Aging and lifelong calorie restriction result in adaptations of skeletal muscle apoptosis repressor, apoptosis-inducing factor, X-linked inhibitor of apoptosis, caspase-3, and caspase-12
    • Dirks AJ, Leeuwenburgh C. Aging and lifelong calorie restriction result in adaptations of skeletal muscle apoptosis repressor, apoptosis-inducing factor, X-linked inhibitor of apoptosis, caspase-3, and caspase-12. Free Radic Biol Med. 2004; 36:27-39.
    • (2004) Free Radic Biol Med. , vol.36 , pp. 27-39
    • Dirks, A.J.1    Leeuwenburgh, C.2
  • 37
    • 22344444732 scopus 로고    scopus 로고
    • The role of apoptosis in agerelated skeletal muscle atrophy
    • Dirks AJ, Leeuwenburgh C. The role of apoptosis in agerelated skeletal muscle atrophy. Sports Med. 2005; 35:473-483.
    • (2005) Sports Med. , vol.35 , pp. 473-483
    • Dirks, A.J.1    Leeuwenburgh, C.2
  • 38
    • 84859517907 scopus 로고    scopus 로고
    • Apoptosis in Skeletal Myocytes: A Potential Target for Interventions against Sarcopenia and Physical Frailty-A Mini-Review
    • Marzetti E, Calvani R, Bernabei R, Leeuwenburgh C. Apoptosis in Skeletal Myocytes: A Potential Target for Interventions against Sarcopenia and Physical Frailty -A Mini-Review. Gerontology. 2011.
    • (2011) Gerontology
    • Marzetti, E.1    Calvani, R.2    Bernabei, R.3    Leeuwenburgh, C.4
  • 39
    • 0024580644 scopus 로고
    • Regulation of skeletal muscle satellite cell proliferation and differentiation by transforming growth factor-beta, insulin-like growth factor I, and fibroblast growth factor
    • Allen RE, Boxhorn LK. Regulation of skeletal muscle satellite cell proliferation and differentiation by transforming growth factor-beta, insulin-like growth factor I, and fibroblast growth factor. J Cell Physiol. 1989; 138:311-315.
    • (1989) J Cell Physiol. , vol.138 , pp. 311-315
    • Allen, R.E.1    Boxhorn, L.K.2
  • 40
    • 0023571274 scopus 로고
    • Inhibition of skeletal muscle satellite cell differentiation by transforming growth factor-beta
    • Allen RE, Boxhorn LK. Inhibition of skeletal muscle satellite cell differentiation by transforming growth factor-beta. J Cell Physiol. 1987; 133:567-572.
    • (1987) J Cell Physiol. , vol.133 , pp. 567-572
    • Allen, R.E.1    Boxhorn, L.K.2
  • 41
    • 1242293760 scopus 로고    scopus 로고
    • Transforming growth factor-beta1 induces the differentiation of myogenic cells into fibrotic cells in injured skeletal muscle: a key event in muscle fibrogenesis
    • Li Y, Foster W, Deasy BM, Chan Y, Prisk V, Tang Y, Cummins J, Huard J. Transforming growth factor-beta1 induces the differentiation of myogenic cells into fibrotic cells in injured skeletal muscle: a key event in muscle fibrogenesis. Am J Pathol. 2004; 164:1007-1019.
    • (2004) Am J Pathol. , vol.164 , pp. 1007-1019
    • Li, Y.1    Foster, W.2    Deasy, B.M.3    Chan, Y.4    Prisk, V.5    Tang, Y.6    Cummins, J.7    Huard, J.8
  • 42
    • 0037444470 scopus 로고    scopus 로고
    • Mitogen-activated protein kinase (MAPK) pathway activation: effects of age and acute exercise on human skeletal muscle
    • Williamson D, Gallagher P, Harber M, Hollon C, Trappe S. Mitogen-activated protein kinase (MAPK) pathway activation: effects of age and acute exercise on human skeletal muscle. J Physiol. 2003; 547:977-987.
    • (2003) J Physiol. , vol.547 , pp. 977-987
    • Williamson, D.1    Gallagher, P.2    Harber, M.3    Hollon, C.4    Trappe, S.5
  • 43
    • 69049102233 scopus 로고    scopus 로고
    • Specific attenuation of protein kinase phosphorylation in muscle with a high mitochondrial content
    • Ljubicic V, Hood DA. Specific attenuation of protein kinase phosphorylation in muscle with a high mitochondrial content. Am J Physiol Endocrinol Metab. 2009; 297:E749-758.
    • (2009) Am J Physiol Endocrinol Metab , vol.297
    • Ljubicic, V.1    Hood, D.A.2
  • 44
    • 37549039009 scopus 로고    scopus 로고
    • A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis
    • Brack AS, Conboy IM, Conboy MJ, Shen J, Rando TA. A temporal switch from notch to Wnt signaling in muscle stem cells is necessary for normal adult myogenesis. Cell Stem Cell. 2008; 2:50-59.
    • (2008) Cell Stem Cell. , vol.2 , pp. 50-59
    • Brack, A.S.1    Conboy, I.M.2    Conboy, M.J.3    Shen, J.4    Rando, T.A.5
  • 45
    • 53349097675 scopus 로고    scopus 로고
    • Canonical Wnt signalling induces satellite-cell proliferation during adult skeletal muscle regeneration
    • Otto A, Schmidt C, Luke G, Allen S, Valasek P, Muntoni F, Lawrence-Watt D, Patel K. Canonical Wnt signalling induces satellite-cell proliferation during adult skeletal muscle regeneration. J Cell Sci. 2008; 121:2939-2950.
    • (2008) J Cell Sci. , vol.121 , pp. 2939-2950
    • Otto, A.1    Schmidt, C.2    Luke, G.3    Allen, S.4    Valasek, P.5    Muntoni, F.6    Lawrence-Watt, D.7    Patel, K.8
  • 46
    • 34547924424 scopus 로고    scopus 로고
    • Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis
    • Brack AS, Conboy MJ, Roy S, Lee M, Kuo CJ, Keller C, Rando TA. Increased Wnt signaling during aging alters muscle stem cell fate and increases fibrosis. Science. 2007; 317:807-810.
    • (2007) Science. , vol.317 , pp. 807-810
    • Brack, A.S.1    Conboy, M.J.2    Roy, S.3    Lee, M.4    Kuo, C.J.5    Keller, C.6    Rando, T.A.7
  • 47
    • 0032416479 scopus 로고    scopus 로고
    • Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function
    • Barton-Davis ER, Shoturma DI, Musaro A, Rosenthal N, Sweeney HL. Viral mediated expression of insulin-like growth factor I blocks the aging-related loss of skeletal muscle function. Proc Natl Acad Sci U S A. 1998; 95:15603-15607.
    • (1998) Proc Natl Acad Sci U S A. , vol.95 , pp. 15603-15607
    • Barton-Davis, E.R.1    Shoturma, D.I.2    Musaro, A.3    Rosenthal, N.4    Sweeney, H.L.5
  • 49
    • 24744441713 scopus 로고    scopus 로고
    • Mammalian target of rapamycin (mTOR) signaling is required for a late-stage fusion process during skeletal myotube maturation
    • Park IH, Chen J. Mammalian target of rapamycin (mTOR) signaling is required for a late-stage fusion process during skeletal myotube maturation. J Biol Chem. 2005; 280:32009-32017.
    • (2005) J Biol Chem. , vol.280 , pp. 32009-32017
    • Park, I.H.1    Chen, J.2
  • 53
    • 23944521632 scopus 로고    scopus 로고
    • Skeletal myocyte hypertrophy requires mTOR kinase activity and S6K1
    • Park IH, Erbay E, Nuzzi P, Chen J. Skeletal myocyte hypertrophy requires mTOR kinase activity and S6K1. Exp Cell Res. 2005; 309:211-219.
    • (2005) Exp Cell Res. , vol.309 , pp. 211-219
    • Park, I.H.1    Erbay, E.2    Nuzzi, P.3    Chen, J.4
  • 54
    • 42149157213 scopus 로고    scopus 로고
    • Leucine-enriched nutrients and the regulation of mammalian target of rapamycin signalling and human skeletal muscle protein synthesis
    • Drummond MJ, Rasmussen BB. Leucine-enriched nutrients and the regulation of mammalian target of rapamycin signalling and human skeletal muscle protein synthesis. Curr Opin Clin Nutr Metab Care. 2008; 11:222-226.
    • (2008) Curr Opin Clin Nutr Metab Care. , vol.11 , pp. 222-226
    • Drummond, M.J.1    Rasmussen, B.B.2
  • 55
    • 33748526240 scopus 로고    scopus 로고
    • Atrophy-related ubiquitin ligases, atrogin-1 and MuRF1 are up-regulated in aged rat Tibialis Anterior muscle
    • Clavel S, Coldefy AS, Kurkdjian E, Salles J, Margaritis I, Derijard B. Atrophy-related ubiquitin ligases, atrogin-1 and MuRF1 are up-regulated in aged rat Tibialis Anterior muscle. Mech Ageing Dev. 2006; 127:794-801.
    • (2006) Mech Ageing Dev. , vol.127 , pp. 794-801
    • Clavel, S.1    Coldefy, A.S.2    Kurkdjian, E.3    Salles, J.4    Margaritis, I.5    Derijard, B.6
  • 56
    • 33746611524 scopus 로고    scopus 로고
    • Atrogin-1/MAFbx and MuRF1 are downregulated in aging-related loss of skeletal muscle
    • Edstrom E, Altun M, Hagglund M, Ulfhake B. Atrogin-1/MAFbx and MuRF1 are downregulated in aging-related loss of skeletal muscle. J Gerontol A Biol Sci Med Sci. 2006; 61:663-674.
    • (2006) J Gerontol A Biol Sci Med Sci. , vol.61 , pp. 663-674
    • Edstrom, E.1    Altun, M.2    Hagglund, M.3    Ulfhake, B.4
  • 59
    • 79851494844 scopus 로고    scopus 로고
    • Mechanisms regulating muscle mass during disuse atrophy and rehabilitation in humans
    • Marimuthu K, Murton AJ, Greenhaff PL. Mechanisms regulating muscle mass during disuse atrophy and rehabilitation in humans. J Appl Physiol. 2011; 110:555-560.
    • (2011) J Appl Physiol. , vol.110 , pp. 555-560
    • Marimuthu, K.1    Murton, A.J.2    Greenhaff, P.L.3
  • 62
    • 0347363477 scopus 로고    scopus 로고
    • Responsiveness of cell signaling pathways during the failed 15-day regrowth of aged skeletal muscle
    • Morris RT, Spangenburg EE, Booth FW. Responsiveness of cell signaling pathways during the failed 15-day regrowth of aged skeletal muscle. J Appl Physiol. 2004; 96:398-404.
    • (2004) J Appl Physiol. , vol.96 , pp. 398-404
    • Morris, R.T.1    Spangenburg, E.E.2    Booth, F.W.3
  • 63
    • 84925970732 scopus 로고    scopus 로고
    • Sarcopenia: prevalence, mechanisms, and functional consequences
    • Berger MJ, Doherty TJ. Sarcopenia: prevalence, mechanisms, and functional consequences. Interdiscip Top Gerontol. 2010; 37:94-114.
    • (2010) Interdiscip Top Gerontol. , vol.37 , pp. 94-114
    • Berger, M.J.1    Doherty, T.J.2
  • 64
    • 0030859469 scopus 로고    scopus 로고
    • Excitation-Ca2+ release-contraction coupling in single aged human skeletal muscle fiber
    • Delbono O, Renganathan M, Messi ML. Excitation-Ca2+ release-contraction coupling in single aged human skeletal muscle fiber. Muscle Nerve Suppl. 1997; 5:S88-92.
    • (1997) Muscle Nerve Suppl , vol.5
    • Delbono, O.1    Renganathan, M.2    Messi, M.L.3
  • 65
    • 0030922504 scopus 로고    scopus 로고
    • Dihydropyridine receptor-ryanodine receptor uncoupling in aged skeletal muscle
    • Renganathan M, Messi ML, Delbono O. Dihydropyridine receptor-ryanodine receptor uncoupling in aged skeletal muscle. J Membr Biol. 1997; 157:247-253.
    • (1997) J Membr Biol. , vol.157 , pp. 247-253
    • Renganathan, M.1    Messi, M.L.2    Delbono, O.3
  • 69
    • 0034933617 scopus 로고    scopus 로고
    • Anorexia, sarcopenia, and aging
    • Morley JE. Anorexia, sarcopenia, and aging. Nutrition. 2001; 17:660-663.
    • (2001) Nutrition. , vol.17 , pp. 660-663
    • Morley, J.E.1
  • 70
    • 0033774882 scopus 로고    scopus 로고
    • IGF-I restores satellite cell proliferative potential in immobilized old skeletal muscle
    • Chakravarthy MV, Davis BS, Booth FW. IGF-I restores satellite cell proliferative potential in immobilized old skeletal muscle. J Appl Physiol. 2000; 89:1365-1379.
    • (2000) J Appl Physiol. , vol.89 , pp. 1365-1379
    • Chakravarthy, M.V.1    Davis, B.S.2    Booth, F.W.3
  • 71
    • 66749174665 scopus 로고    scopus 로고
    • A novel hindlimb immobilization procedure for studying skeletal muscle atrophy and recovery in mouse
    • Caron AZ, Drouin G, Desrosiers J, Trensz F, Grenier G. A novel hindlimb immobilization procedure for studying skeletal muscle atrophy and recovery in mouse. J Appl Physiol. 2009; 106:2049-2059.
    • (2009) J Appl Physiol. , vol.106 , pp. 2049-2059
    • Caron, A.Z.1    Drouin, G.2    Desrosiers, J.3    Trensz, F.4    Grenier, G.5
  • 72
    • 33845209693 scopus 로고    scopus 로고
    • Skeletal muscle apoptosis, sarcopenia and frailty at old age
    • Marzetti E, Leeuwenburgh C. Skeletal muscle apoptosis, sarcopenia and frailty at old age. Exp Gerontol. 2006; 41:1234-1238.
    • (2006) Exp Gerontol. , vol.41 , pp. 1234-1238
    • Marzetti, E.1    Leeuwenburgh, C.2
  • 73
    • 0024656069 scopus 로고
    • The effect of retarded growth upon the length of life span and upon the ultimate body size
    • discussion 172
    • McCay CM, Crowell MF, Maynard LA. The effect of retarded growth upon the length of life span and upon the ultimate body size. 1935. Nutrition. 1989; 5:155-171; discussion 172.
    • (1989) 1935. Nutrition , vol.5 , pp. 155-171
    • McCay, C.M.1    Crowell, M.F.2    Maynard, L.A.3
  • 74
    • 40849139052 scopus 로고    scopus 로고
    • Lifelong exercise and mild (8%) caloric restriction attenuate age-induced alterations in plantaris muscle morphology, oxidative stress and IGF-1 in the Fischer-344 rat
    • Kim JH, Kwak HB, Leeuwenburgh C, Lawler JM. Lifelong exercise and mild (8%) caloric restriction attenuate age-induced alterations in plantaris muscle morphology, oxidative stress and IGF-1 in the Fischer-344 rat. Exp Gerontol. 2008; 43:317-329.
    • (2008) Exp Gerontol. , vol.43 , pp. 317-329
    • Kim, J.H.1    Kwak, H.B.2    Leeuwenburgh, C.3    Lawler, J.M.4
  • 75
    • 0032442835 scopus 로고    scopus 로고
    • Influences of caloric restriction on age-associated skeletal muscle fiber characteristics and mitochondrial changes in rats and mice
    • Lee CM, Aspnes LE, Chung SS, Weindruch R, Aiken JM. Influences of caloric restriction on age-associated skeletal muscle fiber characteristics and mitochondrial changes in rats and mice. Ann N Y Acad Sci. 1998; 854:182-191.
    • (1998) Ann N Y Acad Sci. , vol.854 , pp. 182-191
    • Lee, C.M.1    Aspnes, L.E.2    Chung, S.S.3    Weindruch, R.4    Aiken, J.M.5
  • 78
    • 2442711771 scopus 로고    scopus 로고
    • Early-onset calorie restriction conserves fiber number in aging rat skeletal muscle
    • McKiernan SH, Bua E, McGorray J, Aiken J. Early-onset calorie restriction conserves fiber number in aging rat skeletal muscle. FASEB J. 2004; 18:580-581.
    • (2004) FASEB J. , vol.18 , pp. 580-581
    • McKiernan, S.H.1    Bua, E.2    McGorray, J.3    Aiken, J.4
  • 79
    • 0032402945 scopus 로고    scopus 로고
    • Caloric restriction prevents age-associated accrual of oxidative damage to mouse skeletal muscle mitochondria
    • Lass A, Sohal BH, Weindruch R, Forster MJ, Sohal RS. Caloric restriction prevents age-associated accrual of oxidative damage to mouse skeletal muscle mitochondria. Free Radic Biol Med. 1998; 25:1089-1097.
    • (1998) Free Radic Biol Med. , vol.25 , pp. 1089-1097
    • Lass, A.1    Sohal, B.H.2    Weindruch, R.3    Forster, M.J.4    Sohal, R.S.5
  • 80
    • 70349661409 scopus 로고    scopus 로고
    • Muscle apoptotic response to denervation, disuse, and aging
    • Siu PM. Muscle apoptotic response to denervation, disuse, and aging. Med Sci Sports Exerc. 2009; 41:1876-1886.
    • (2009) Med Sci Sports Exerc. , vol.41 , pp. 1876-1886
    • Siu, P.M.1
  • 81
    • 0032500822 scopus 로고    scopus 로고
    • Effectiveness of caloric restriction in preventing age-related changes in rat skeletal muscle
    • Mayhew M, Renganathan M, Delbono O. Effectiveness of caloric restriction in preventing age-related changes in rat skeletal muscle. Biochem Biophys Res Commun. 1998; 251:95-99.
    • (1998) Biochem Biophys Res Commun. , vol.251 , pp. 95-99
    • Mayhew, M.1    Renganathan, M.2    Delbono, O.3
  • 82
    • 0032407815 scopus 로고    scopus 로고
    • Caloric restriction prevents agerelated decline in skeletal muscle dihydropyridine receptor and ryanodine receptor expression
    • Renganathan M, Delbono O. Caloric restriction prevents agerelated decline in skeletal muscle dihydropyridine receptor and ryanodine receptor expression. FEBS Lett. 1998; 434:346-350.
    • (1998) FEBS Lett. , vol.434 , pp. 346-350
    • Renganathan, M.1    Delbono, O.2
  • 83
    • 28244466940 scopus 로고    scopus 로고
    • Caloric restriction in humans: potential pitfalls and health concerns
    • Dirks AJ, Leeuwenburgh C. Caloric restriction in humans: potential pitfalls and health concerns. Mech Ageing Dev. 2006; 127:1-7.
    • (2006) Mech Ageing Dev. , vol.127 , pp. 1-7
    • Dirks, A.J.1    Leeuwenburgh, C.2
  • 84
    • 34247153540 scopus 로고    scopus 로고
    • Starving for life: what animal studies can and cannot tell us about the use of caloric restriction to prolong human lifespan
    • Speakman JR, Hambly C. Starving for life: what animal studies can and cannot tell us about the use of caloric restriction to prolong human lifespan. J Nutr. 2007; 137:1078-1086.
    • (2007) J Nutr. , vol.137 , pp. 1078-1086
    • Speakman, J.R.1    Hambly, C.2
  • 89
    • 3042648746 scopus 로고    scopus 로고
    • Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway
    • Kapahi P, Zid BM, Harper T, Koslover D, Sapin V, Benzer S. Regulation of lifespan in Drosophila by modulation of genes in the TOR signaling pathway. Curr Biol. 2004; 14:885-890.
    • (2004) Curr Biol. , vol.14 , pp. 885-890
    • Kapahi, P.1    Zid, B.M.2    Harper, T.3    Koslover, D.4    Sapin, V.5    Benzer, S.6
  • 90
    • 0027771804 scopus 로고
    • Tabtiang R. A C. elegans mutant that lives twice as long as wild type
    • Kenyon C, Chang J, Gensch E, Rudner A, Tabtiang R. A C. elegans mutant that lives twice as long as wild type. Nature. 1993; 366:461-464.
    • (1993) Nature , vol.366 , pp. 461-464
    • Kenyon, C.1    Chang, J.2    Gensch, E.3    Rudner, A.4
  • 91
    • 10644282295 scopus 로고    scopus 로고
    • The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans
    • Apfeld J, O'Connor G, McDonagh T, DiStefano PS, Curtis R. The AMP-activated protein kinase AAK-2 links energy levels and insulin-like signals to lifespan in C. elegans. Genes Dev. 2004; 18:3004-3009.
    • (2004) Genes Dev. , vol.18 , pp. 3004-3009
    • Apfeld, J.1    O'Connor, G.2    McDonagh, T.3    DiStefano, P.S.4    Curtis, R.5
  • 93
    • 0034659785 scopus 로고    scopus 로고
    • Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain
    • Owen MR, Doran E, Halestrap AP. Evidence that metformin exerts its anti-diabetic effects through inhibition of complex 1 of the mitochondrial respiratory chain. Biochem J. 2000; 348 Pt 3:607-614.
    • (2000) Biochem J , vol.348 , Issue.PT. 3 , pp. 607-614
    • Owen, M.R.1    Doran, E.2    Halestrap, A.P.3
  • 94
    • 0015342907 scopus 로고
    • Effects of metformin on glucose uptake by the isolated rat diaphragm
    • Adnitt PI, Frayn KN. Effects of metformin on glucose uptake by the isolated rat diaphragm. Br J Pharmacol. 1972; 45:152P-153P.
    • (1972) Br J Pharmacol. , vol.45
    • Adnitt, P.I.1    Frayn, K.N.2
  • 95
    • 0015697692 scopus 로고
    • Effects of metformin on glucose uptake by isolated human skeletal muscle
    • Adnitt PI, Frayn KN, Turner P. Effects of metformin on glucose uptake by isolated human skeletal muscle. Br J Pharmacol. 1973; 47:617P-618P.
    • (1973) Br J Pharmacol. , vol.47
    • Adnitt, P.I.1    Frayn, K.N.2    Turner, P.3
  • 96
    • 77649311383 scopus 로고    scopus 로고
    • Metformin induces a dietary restrictionlike state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1
    • Onken B, Driscoll M. Metformin induces a dietary restrictionlike state and the oxidative stress response to extend C. elegans Healthspan via AMPK, LKB1, and SKN-1. PLoS One. 2010; 5:e8758.
    • (2010) PLoS One. , vol.5
    • Onken, B.1    Driscoll, M.2
  • 98
    • 78649872952 scopus 로고    scopus 로고
    • Life span extension by resveratrol, rapamycin, and metformin: The promise of dietary restriction mimetics for an healthy aging
    • Mouchiroud L, Molin L, Dalliere N, Solari F. Life span extension by resveratrol, rapamycin, and metformin: The promise of dietary restriction mimetics for an healthy aging. Biofactors. 2010; 36:377-382.
    • (2010) Biofactors. , vol.36 , pp. 377-382
    • Mouchiroud, L.1    Molin, L.2    Dalliere, N.3    Solari, F.4
  • 100
    • 78851472160 scopus 로고    scopus 로고
    • Resveratrol in cardiovascular health and disease
    • Petrovski G, Gurusamy N, Das DK. Resveratrol in cardiovascular health and disease. Ann N Y Acad Sci. 2011; 1215:22-33.
    • (2011) Ann N Y Acad Sci. , vol.1215 , pp. 22-33
    • Petrovski, G.1    Gurusamy, N.2    Das, D.K.3
  • 103
    • 43549088782 scopus 로고    scopus 로고
    • Resveratrol: a multitargeted agent for age-associated chronic diseases
    • Harikumar KB, Aggarwal BB. Resveratrol: a multitargeted agent for age-associated chronic diseases. Cell Cycle. 2008; 7:1020-1035.
    • (2008) Cell Cycle. , vol.7 , pp. 1020-1035
    • Harikumar, K.B.1    Aggarwal, B.B.2
  • 104
    • 76549104638 scopus 로고    scopus 로고
    • Resveratrol and rapamycin: are they antiaging drugs?
    • Kaeberlein M. Resveratrol and rapamycin: are they antiaging drugs? Bioessays. 2010; 32:96-99.
    • (2010) Bioessays , vol.32 , pp. 96-99
    • Kaeberlein, M.1
  • 105
    • 3242777031 scopus 로고    scopus 로고
    • Chronic activation of AMP-activated kinase as a strategy for slowing aging
    • McCarty MF. Chronic activation of AMP-activated kinase as a strategy for slowing aging. Med Hypotheses. 2004; 63:334-339.
    • (2004) Med Hypotheses. , vol.63 , pp. 334-339
    • McCarty, M.F.1
  • 108
    • 78649851597 scopus 로고    scopus 로고
    • Mediation of endogenous antioxidant enzymes and apoptotic signaling by resveratrol following muscle disuse in the gastrocnemius muscles of young and old rats
    • Jackson JR, Ryan MJ, Hao Y, Alway SE. Mediation of endogenous antioxidant enzymes and apoptotic signaling by resveratrol following muscle disuse in the gastrocnemius muscles of young and old rats. Am J Physiol Regul Integr Comp Physiol. 2010; 299:R1572-1581.
    • (2010) Am J Physiol Regul Integr Comp Physiol , vol.299
    • Jackson, J.R.1    Ryan, M.J.2    Hao, Y.3    Alway, S.E.4
  • 109
    • 79961092644 scopus 로고    scopus 로고
    • Long-term supplementation with resveratrol alleviates oxidative stress but does not attenuate sarcopenia in aged mice
    • Jackson JR, Ryan MJ, Alway SE. Long-term supplementation with resveratrol alleviates oxidative stress but does not attenuate sarcopenia in aged mice. J Gerontol A Biol Sci Med Sci. 2011; 66:751-764.
    • (2011) J Gerontol A Biol Sci Med Sci. , vol.66 , pp. 751-764
    • Jackson, J.R.1    Ryan, M.J.2    Alway, S.E.3
  • 111
    • 55849152355 scopus 로고    scopus 로고
    • Aging: ROS or TOR
    • Blagosklonny MV. Aging: ROS or TOR. Cell Cycle. 2008; 7:3344-3354.
    • (2008) Cell Cycle. , vol.7 , pp. 3344-3354
    • Blagosklonny, M.V.1
  • 112
    • 67649369072 scopus 로고    scopus 로고
    • At concentrations that inhibit mTOR, resveratrol suppresses cellular senescence
    • Demidenko ZN, Blagosklonny MV. At concentrations that inhibit mTOR, resveratrol suppresses cellular senescence. Cell Cycle. 2009; 8:1901-1904.
    • (2009) Cell Cycle. , vol.8 , pp. 1901-1904
    • Demidenko, Z.N.1    Blagosklonny, M.V.2
  • 116
    • 0029821187 scopus 로고    scopus 로고
    • Effects of FK506 and rapamycin on excitation-contraction coupling in skeletal muscle fibres of the rat
    • Lamb GD, Stephenson DG. Effects of FK506 and rapamycin on excitation-contraction coupling in skeletal muscle fibres of the rat. J Physiol. 1996; 494 (Pt 2):569-576.
    • (1996) J Physiol , vol.494 , Issue.PT. 2 , pp. 569-576
    • Lamb, G.D.1    Stephenson, D.G.2
  • 117
    • 21344456744 scopus 로고    scopus 로고
    • Rapamycin and FK506 reduce skeletal muscle voltage sensor expression and function
    • Avila G, Dirksen RT. Rapamycin and FK506 reduce skeletal muscle voltage sensor expression and function. Cell Calcium. 2005; 38:35-44.
    • (2005) Cell Calcium. , vol.38 , pp. 35-44
    • Avila, G.1    Dirksen, R.T.2
  • 120
    • 74949086718 scopus 로고    scopus 로고
    • Testosterone supplementation reverses sarcopenia in aging through regulation of myostatin, c-Jun NH2-terminal kinase, Notch, and Akt signaling pathways
    • Kovacheva EL, Hikim AP, Shen R, Sinha I, Sinha-Hikim I. Testosterone supplementation reverses sarcopenia in aging through regulation of myostatin, c-Jun NH2-terminal kinase, Notch, and Akt signaling pathways. Endocrinology. 2010; 151:628-638.
    • (2010) Endocrinology. , vol.151 , pp. 628-638
    • Kovacheva, E.L.1    Hikim, A.P.2    Shen, R.3    Sinha, I.4    Sinha-Hikim, I.5
  • 122
    • 22544451284 scopus 로고    scopus 로고
    • Androgen regulation of satellite cell function
    • Chen Y, Zajac JD, MacLean HE. Androgen regulation of satellite cell function. J Endocrinol. 2005; 186:21-31.
    • (2005) J Endocrinol. , vol.186 , pp. 21-31
    • Chen, Y.1    Zajac, J.D.2    MacLean, H.E.3
  • 123
    • 0026742650 scopus 로고
    • Effects of testosterone supplementation in the aging male
    • Tenover JS. Effects of testosterone supplementation in the aging male. J Clin Endocrinol Metab. 1992; 75:1092-1098.
    • (1992) J Clin Endocrinol Metab. , vol.75 , pp. 1092-1098
    • Tenover, J.S.1
  • 127
    • 70449359214 scopus 로고    scopus 로고
    • Developing novel therapeutic approaches to frailty
    • Morley JE. Developing novel therapeutic approaches to frailty. Curr Pharm Des. 2009; 15:3384-3395.
    • (2009) Curr Pharm Des. , vol.15 , pp. 3384-3395
    • Morley, J.E.1
  • 128
    • 33847184616 scopus 로고    scopus 로고
    • Expanding the therapeutic use of androgens via selective androgen receptor modulators (SARMs)
    • Gao W, Dalton JT. Expanding the therapeutic use of androgens via selective androgen receptor modulators (SARMs). Drug Discov Today. 2007; 12:241-248.
    • (2007) Drug Discov Today. , vol.12 , pp. 241-248
    • Gao, W.1    Dalton, J.T.2
  • 129
    • 39349102199 scopus 로고    scopus 로고
    • Role of the renin-angiotensin system in age-related sarcopenia and diastolic dysfunction
    • Carter CS, Groban L. Role of the renin-angiotensin system in age-related sarcopenia and diastolic dysfunction. Aging health. 2008; 4:37-46.
    • (2008) Aging health. , vol.4 , pp. 37-46
    • Carter, C.S.1    Groban, L.2
  • 132
    • 73249136316 scopus 로고    scopus 로고
    • ACE-inhibition and physical function: results from the Trial of Angiotensin-Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study
    • Cesari M, Pedone C, Incalzi RA, Pahor M. ACE-inhibition and physical function: results from the Trial of Angiotensin-Converting Enzyme Inhibition and Novel Cardiovascular Risk Factors (TRAIN) study. J Am Med Dir Assoc. 2010; 11:26-32.
    • (2010) J Am Med Dir Assoc. , vol.11 , pp. 26-32
    • Cesari, M.1    Pedone, C.2    Incalzi, R.A.3    Pahor, M.4
  • 133
    • 35349021592 scopus 로고    scopus 로고
    • Effect of perindopril on physical function in elderly people with functional impairment: a randomized controlled trial
    • Sumukadas D, Witham MD, Struthers AD, McMurdo ME. Effect of perindopril on physical function in elderly people with functional impairment: a randomized controlled trial. CMAJ. 2007; 177:867-874.
    • (2007) CMAJ. , vol.177 , pp. 867-874
    • Sumukadas, D.1    Witham, M.D.2    Struthers, A.D.3    McMurdo, M.E.4
  • 135
    • 77953078946 scopus 로고    scopus 로고
    • Counteracting muscle wasting in aging and neuromuscular diseases: the critical role of IGF-1
    • Scicchitano BM, Rizzuto E, Musaro A. Counteracting muscle wasting in aging and neuromuscular diseases: the critical role of IGF-1. Aging. 2009; 1:451-457.
    • (2009) Aging. , vol.1 , pp. 451-457
    • Scicchitano, B.M.1    Rizzuto, E.2    Musaro, A.3
  • 136
    • 0032582711 scopus 로고    scopus 로고
    • Overexpression of IGF-1 exclusively in skeletal muscle prevents age-related decline in the number of dihydropyridine receptors
    • Renganathan M, Messi ML, Delbono O. Overexpression of IGF-1 exclusively in skeletal muscle prevents age-related decline in the number of dihydropyridine receptors. J Biol Chem. 1998; 273:28845-28851.
    • (1998) J Biol Chem. , vol.273 , pp. 28845-28851
    • Renganathan, M.1    Messi, M.L.2    Delbono, O.3
  • 137
    • 0029040848 scopus 로고
    • Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice
    • Coleman ME, DeMayo F, Yin KC, Lee HM, Geske R, Montgomery C, Schwartz RJ. Myogenic vector expression of insulin-like growth factor I stimulates muscle cell differentiation and myofiber hypertrophy in transgenic mice. J Biol Chem. 1995; 270:12109-12116.
    • (1995) J Biol Chem. , vol.270 , pp. 12109-12116
    • Coleman, M.E.1    DeMayo, F.2    Yin, K.C.3    Lee, H.M.4    Geske, R.5    Montgomery, C.6    Schwartz, R.J.7
  • 138
    • 0033228631 scopus 로고    scopus 로고
    • Local insulin-like growth factor I expression induces physiologic, then pathologic, cardiac hypertrophy in transgenic mice
    • Delaughter MC, Taffet GE, Fiorotto ML, Entman ML, Schwartz RJ. Local insulin-like growth factor I expression induces physiologic, then pathologic, cardiac hypertrophy in transgenic mice. FASEB J. 1999; 13:1923-1929.
    • (1999) FASEB J. , vol.13 , pp. 1923-1929
    • Delaughter, M.C.1    Taffet, G.E.2    Fiorotto, M.L.3    Entman, M.L.4    Schwartz, R.J.5


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