-
1
-
-
0029804116
-
Mechanism of activation of protein kinase B by insulin and IGF-1
-
Alessi DR, Andjelkovic M, Caudwell B, Cron P, Morrice N, Cohen P, Hemmings BA. Mechanism of activation of protein kinase B by insulin and IGF-1. EMBO J 15:6541-6551, 1996. (Pubitemid 26413787)
-
(1996)
EMBO Journal
, vol.15
, Issue.23
, pp. 6541-6551
-
-
Alessi, D.R.1
Andjelkovic, M.2
Caudwell, B.3
Cron, P.4
Morrice, N.5
Cohen, P.6
Hemmings, B.A.7
-
2
-
-
78650046347
-
Muscle wasting in aged, sarcopenic rats is associated with enhanced activity of the ubiquitin proteasome pathway
-
Altun M, Besche HC, Overkleeft HS, Piccirillo R, Edelmann MJ, Kessler BM, Goldberg AL, Ulfhake B. Muscle wasting in aged, sarcopenic rats is associated with enhanced activity of the ubiquitin proteasome pathway. J Biol Chem 285:39597-39608.
-
J Biol Chem
, vol.285
, pp. 39597-39608
-
-
Altun, M.1
Besche, H.C.2
Overkleeft, H.S.3
Piccirillo, R.4
Edelmann, M.J.5
Kessler, B.M.6
Goldberg, A.L.7
Ulfhake, B.8
-
3
-
-
0030707838
-
Effects of aging on in vivo synthesis of skeletal muscle myosin heavy-chain and sarcoplasmic protein in humans
-
Balagopal P, Rooyackers OE, Adey DB, Ades PA, Nair KS. Effects of aging on in vivo synthesis of skeletal muscle myosin heavy-chain and sarcoplasmic protein in humans. Am J Physiol Endocrinol Metab 273:E790-E800, 1997.
-
(1997)
Am J Physiol Endocrinol Metab
, vol.273
-
-
Balagopal, P.1
Rooyackers, O.E.2
Adey, D.B.3
Ades, P.A.4
Nair, K.S.5
-
4
-
-
0035941020
-
Identification of ubiquitin ligases required for skeletal Muscle Atrophy
-
DOI 10.1126/science.1065874
-
Bodine SC, Latres E, Baumhueter S, Lai VK, Nunez L, Clarke BA, Poueymirou WT, Panaro FJ, Na E, Dharmarajan K, Pan ZQ, Valenzuela DM, DeChiara TM, Stitt TN, Yancopoulos GD, Glass DJ. Identification of ubiquitin ligases required for skeletal muscle atrophy. Science 294:1704-1708, 2001. (Pubitemid 33104839)
-
(2001)
Science
, vol.294
, Issue.5547
, pp. 1704-1708
-
-
Bodine, S.C.1
Latres, E.2
Baumhueter, S.3
Lai, V.K.-M.4
Nunez, L.5
Clarke, B.A.6
Poueymirou, W.T.7
Panaro, F.J.8
Erqian, N.9
Dharmarajan, K.10
Pan, Z.-Q.11
Valenzuela, D.M.12
Dechiara, T.M.13
Stitt, T.N.14
Yancopoulos, G.D.15
Glass, D.J.16
-
5
-
-
33748526240
-
Atrophy-related ubiquitin ligases, atrogin-1 and MuRF1 are up-regulated in aged rat Tibialis Anterior muscle
-
DOI 10.1016/j.mad.2006.07.005, PII S0047637406001709
-
Clavel S, Coldefy AS, Kurkdjian E, Salles J, Margaritis I, Derijard B. Atrophy-related ubiquitin ligases, atrogin-1 and MuRF1 are up-regulated in aged rat tibialis anterior muscle. Mech Ageing Dev 127:794-801, 2006. (Pubitemid 44374662)
-
(2006)
Mechanisms of Ageing and Development
, vol.127
, Issue.10
, pp. 794-801
-
-
Clavel, S.1
Coldefy, A.-S.2
Kurkdjian, E.3
Salles, J.4
Margaritis, I.5
Derijard, B.6
-
6
-
-
58149129428
-
Skeletal muscle proteolysis in aging
-
Combaret L, Dardevet D, Bechet D, Taillandier D, Mosoni L, Attaix D. Skeletal muscle proteolysis in aging. Curr Opin Clin Nutr Metab Care 12:37-41, 2009.
-
(2009)
Curr Opin Clin Nutr Metab Care
, vol.12
, pp. 37-41
-
-
Combaret, L.1
Dardevet, D.2
Bechet, D.3
Taillandier, D.4
Mosoni, L.5
Attaix, D.6
-
7
-
-
0019818758
-
Glucose intolerance and aging
-
DeFronzo RA. Glucose intolerance and aging. Diabetes Care 4:493-501, 1981. (Pubitemid 12210105)
-
(1981)
Diabetes Care
, vol.4
, Issue.4
, pp. 493-501
-
-
DeFronzo, R.A.1
-
8
-
-
33746611524
-
Atrogin-1/MAFbx and MuRF1 are downregulated in aging-related loss of skeletal muscle
-
Edstrom E, Altun M, Hagglund M, Ulfhake B. Atrogin-1/MAFbx and MuRF1 are downregulated in aging-related loss of skeletal muscle. J Gerontol A Biol Sci Med Sci 61:663-674, 2006. (Pubitemid 44148351)
-
(2006)
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
, vol.61
, Issue.7
, pp. 663-674
-
-
Edstrom, E.1
Altun, M.2
Hagglund, M.3
Ulfhake, B.4
-
9
-
-
78049239888
-
Frailty and muscle metabolism dysregulation in the elderly
-
Evans WJ, Paolisso G, Abbatecola AM, Corsonello A, Bustacchini S, Strollo F, Lattanzio F. Frailty and muscle metabolism dysregulation in the elderly. Biogerontology 11:527-536, 2010.
-
(2010)
Biogerontology
, vol.11
, pp. 527-536
-
-
Evans, W.J.1
Paolisso, G.2
Abbatecola, A.M.3
Corsonello, A.4
Bustacchini, S.5
Strollo, F.6
Lattanzio, F.7
-
10
-
-
0142084679
-
Akt promotes increased mammalian cell size by stimulating protein synthesis and inhibiting protein degradation
-
Faridi J, Fawcett J, Wang L, Roth RA. Akt promotes increased mammalian cell size by stimulating protein synthesis and inhibiting protein degradation. Am J Physiol Endocrinol Metab 285:E964-E972, 2003. (Pubitemid 37296317)
-
(2003)
American Journal of Physiology - Endocrinology and Metabolism
, vol.285
, Issue.5
-
-
Faridi, J.1
Fawcett, J.2
Wang, L.3
Roth, R.A.4
-
11
-
-
34249678700
-
Aerobic exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mammalian target of rapamycin signaling
-
DOI 10.2337/db06-1566
-
Fujita S, Rasmussen BB, Cadenas JG, Drummond MJ, Glynn EL, Sattler FR, Volpi E. Aerobic exercise overcomes the age-related insulin resistance of muscle protein metabolism by improving endothelial function and Akt/mammalian target of rapamycin signaling. Diabetes 56:1615-1622, 2007. (Pubitemid 46842620)
-
(2007)
Diabetes
, vol.56
, Issue.6
, pp. 1615-1622
-
-
Fujita, S.1
Rasmussen, B.B.2
Cadenas, J.G.3
Drummond, M.J.4
Glynn, E.L.5
Sattler, F.R.6
Volpi, E.7
-
12
-
-
0025287267
-
Role of different proteolytic systems in the degradation of muscle proteins during denervation atrophy
-
Furuno K, Goodman MN, Goldberg AL. Role of different proteolytic systems in the degradation of muscle proteins during denervation atrophy. J Biol Chem 265:8550-8557, 1990.
-
(1990)
J Biol Chem
, vol.265
, pp. 8550-8557
-
-
Furuno, K.1
Goodman, M.N.2
Goldberg, A.L.3
-
13
-
-
69249208791
-
The Akt kinases: Isoform specificity in metabolism and cancer
-
Gonzalez E, McGraw TE. The Akt kinases: isoform specificity in metabolism and cancer. Cell Cycle 8:2502-2508, 2009.
-
(2009)
Cell Cycle
, vol.8
, pp. 2502-2508
-
-
Gonzalez, E.1
McGraw, T.E.2
-
14
-
-
0346499181
-
The Healthcare Costs of Sarcopenia in the United States
-
DOI 10.1111/j.1532-5415.2004.52014.x
-
Janssen I, Shepard DS, Katzmarzyk PT, Roubenoff R. The healthcare costs of sarcopenia in the United States. J Am Geriatr Soc 52:80-85, 2004. (Pubitemid 38090394)
-
(2004)
Journal of the American Geriatrics Society
, vol.52
, Issue.1
, pp. 80-85
-
-
Janssen, I.1
Shepard, D.S.2
Katzmarzyk, P.T.3
Roubenoff, R.4
-
15
-
-
4544298823
-
Assessment of biomarkers of protein anabolism in skeletal muscle during the life span of the rat: Sarcopenia despite elevated protein synthesis
-
DOI 10.1152/ajpendo.00535.2003
-
Kimball SR, O'Malley JP, Anthony JC, Crozier SJ, Jefferson LS. Assessment of biomarkers of protein anabolism in skeletal muscle during the life span of the rat: sarcopenia despite elevated protein synthesis. Am J Physiol Endocrinol Metab 287:E772-E780, 2004. (Pubitemid 39237908)
-
(2004)
American Journal of Physiology - Endocrinology and Metabolism
, vol.287
, Issue.4
-
-
Kimball, S.R.1
O'Malley, J.P.2
Anthony, J.C.3
Crozier, S.J.4
Jefferson, L.S.5
-
16
-
-
0347285363
-
Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression
-
DOI 10.1096/fj.03-0610com
-
Lecker SH, Jagoe RT, Gilbert A, Gomes M, Baracos V, Bailey J, Price SR, Mitch WE, Goldberg AL. Multiple types of skeletal muscle atrophy involve a common program of changes in gene expression. FASEB J 18:39-51, 2004. (Pubitemid 38076464)
-
(2004)
FASEB Journal
, vol.18
, Issue.1
, pp. 39-51
-
-
Lecker, S.H.1
Jagoe, R.T.2
Gilbert, A.3
Gomes, M.4
Baracos, V.5
Bailey, J.6
Price, S.R.7
Mitch, W.E.8
Goldberg, A.L.9
-
17
-
-
36448940798
-
FoxO3 Controls Autophagy in Skeletal Muscle In Vivo
-
DOI 10.1016/j.cmet.2007.11.001, PII S1550413107003361
-
Mammucari C, Milan G, Romanello V, Masiero E, Rudolf R, Del Piccolo P, Burden SJ, Di Lisi R, Sandri C, Zhao J, Goldberg AL, Schiaffino S, Sandri M. FoxO3 controls autophagy in skeletal muscle in vivo. Cell Metab 6:458-471, 2007. (Pubitemid 350163055)
-
(2007)
Cell Metabolism
, vol.6
, Issue.6
, pp. 458-471
-
-
Mammucari, C.1
Milan, G.2
Romanello, V.3
Masiero, E.4
Rudolf, R.5
Del Piccolo, P.6
Burden, S.J.7
Di Lisi, R.8
Sandri, C.9
Zhao, J.10
Goldberg, A.L.11
Schiaffino, S.12
Sandri, M.13
-
18
-
-
70449927247
-
Autophagy is required to maintain muscle mass
-
Masiero E, Agatea L, Mammucari C, Blaauw B, Loro E, Komatsu M, Metzger D, Reggiani C, Schiaffino S, Sandri M. Autophagy is required to maintain muscle mass. Cell Metab 10:507-515, 2009.
-
(2009)
Cell Metab
, vol.10
, pp. 507-515
-
-
Masiero, E.1
Agatea, L.2
Mammucari, C.3
Blaauw, B.4
Loro, E.5
Komatsu, M.6
Metzger, D.7
Reggiani, C.8
Schiaffino, S.9
Sandri, M.10
-
19
-
-
12644286565
-
Determinants of protein turnover in health and disease
-
DOI 10.1159/000057344
-
Newby FD, Price SR. Determinants of protein turnover in health and disease. Miner Electrolyte Metab 24:6-12, 1998. (Pubitemid 27483615)
-
(1998)
Mineral and Electrolyte Metabolism
, vol.24
, Issue.1
, pp. 6-12
-
-
Newby, F.D.1
Price, S.R.2
-
20
-
-
0029861468
-
Muscle wasting in insulinopenic rats results from activation of the ATP- dependent, ubiquitin-proteasome proteolytic pathway by a mechanism including gene transcription
-
Price SR, Bailey JL, Wang X, Jurkovitz C, England BK, Ding X, Phillips LS, Mitch WE. Muscle wasting in insulinopenic rats results from activation of the ATP-dependent, ubiquitin-proteasome proteolytic pathway by a mechanism including gene transcription. J Clin Invest 98:1703-1708, 1996. (Pubitemid 26359185)
-
(1996)
Journal of Clinical Investigation
, vol.98
, Issue.8
, pp. 1703-1708
-
-
Price, S.R.1
Bailey, J.L.2
Wang, X.3
Jurkovitz, C.4
England, B.K.5
Ding, X.6
Phillips, L.S.7
Mitch, W.E.8
-
21
-
-
33646267446
-
Insulin resistance of muscle protein metabolism in aging
-
DOI 10.1096/fj.05-4607fje
-
Rasmussen BB, Fujita S, Wolfe RR, Mittendorfer B, Roy M, Rowe VL, Volpi E. Insulin resistance of muscle protein metabolism in aging. FASEB J 20:768-769, 2006. (Pubitemid 46671209)
-
(2006)
FASEB Journal
, vol.20
, Issue.6
, pp. 768-769
-
-
Rasmussen, B.B.1
Fujita, S.2
Wolfe, R.R.3
Mittendorfer, B.4
Roy, M.5
Rowe, V.L.6
Volpi, E.7
-
22
-
-
0026954068
-
Gas chromatographic/mass spectrometric analysis of stable isotopes of 3-methylhistidine in biological fluids: Application to plasma kinetics in vivo
-
Rathmacher JA, Link GA, Flakoll PJ, Nissen SL. Gas chromatographic/mass spectrometric analysis of stable isotopes of 3-methylhistidine in biological fluids: application to plasma kinetics in vivo. Biol Mass Spectrom 21:560-566, 1992.
-
(1992)
Biol Mass Spectrom
, vol.21
, pp. 560-566
-
-
Rathmacher, J.A.1
Link, G.A.2
Flakoll, P.J.3
Nissen, S.L.4
-
23
-
-
38749140252
-
Proteolytic gene expression differs at rest and after resistance exercise between young and old women
-
Raue U, Slivka D, Jemiolo B, Hollon C, Trappe S. Proteolytic gene expression differs at rest and after resistance exercise between young and old women. J Gerontol A Biol Sci Med Sci 62:1407-1412, 2007. (Pubitemid 351175611)
-
(2007)
Journals of Gerontology - Series A Biological Sciences and Medical Sciences
, vol.62
, Issue.12
, pp. 1407-1412
-
-
Raue, U.1
Slivka, D.2
Jemiolo, B.3
Hollon, C.4
Trappe, S.5
-
24
-
-
4544293878
-
IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1
-
DOI 10.1152/ajpendo.00073.2004
-
Sacheck JM, Ohtsuka A, McLary SC, Goldberg AL. IGF-I stimulates muscle growth by suppressing protein breakdown and expression of atrophy-related ubiquitin ligases, atrogin-1 and MuRF1. Am J Physiol Endocrinol Metab 287:E591-E601, 2004. (Pubitemid 39242684)
-
(2004)
American Journal of Physiology - Endocrinology and Metabolism
, vol.287
, Issue.4
-
-
Sacheck, J.M.1
Ohtsuka, A.2
McLary, S.C.3
Goldberg, A.L.4
-
25
-
-
11144356337
-
Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy
-
DOI 10.1016/S0092-8674(04)00400-3, PII S0092867404004003
-
Sandri M, Sandri C, Gilbert A, Skurk C, Calabria E, Picard A, Walsh K, Schiaffino S, Lecker SH, Goldberg AL. Foxo transcription factors induce the atrophy-related ubiquitin ligase atrogin-1 and cause skeletal muscle atrophy. Cell 117:399-412, 2004. (Pubitemid 38534545)
-
(2004)
Cell
, vol.117
, Issue.3
, pp. 399-412
-
-
Sandri, M.1
Sandri, C.2
Gilbert, A.3
Skurk, C.4
Calabria, E.5
Picard, A.6
Walsh, K.7
Schiaffino, S.8
Lecker, S.H.9
Goldberg, A.L.10
-
26
-
-
13844312400
-
Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex
-
DOI 10.1126/science.1106148
-
Sarbassov DD, Guertin DA, Ali SM, Sabatini DM. Phosphorylation and regulation of Akt/PKB by the rictor-mTOR complex. Science 307:1098-1101, 2005. (Pubitemid 40262113)
-
(2005)
Science
, vol.307
, Issue.5712
, pp. 1098-1101
-
-
Sarbassov, D.D.1
Guertin, D.A.2
Ali, S.M.3
Sabatini, D.M.4
-
27
-
-
1842339868
-
Inhibitors of the proteasome reduce the accelerated proteolysis in atrophying rat skeletal muscles
-
Tawa NE Jr, Odessey R, Goldberg AL. Inhibitors of the proteasome reduce the accelerated proteolysis in atrophying rat skeletal muscles. J Clin Invest 100:197-203, 1997. (Pubitemid 27311258)
-
(1997)
Journal of Clinical Investigation
, vol.100
, Issue.1
, pp. 197-203
-
-
Tawa Jr., N.E.1
Odessey, R.2
Goldberg, A.L.3
-
29
-
-
0020081889
-
Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle?
-
Tischler ME, Desautels M, Goldberg AL. Does leucine, leucyl-tRNA, or some metabolite of leucine regulate protein synthesis and degradation in skeletal and cardiac muscle? J Biol Chem 257:1613-1621, 1982. (Pubitemid 12157110)
-
(1982)
Journal of Biological Chemistry
, vol.257
, Issue.4
, pp. 1613-1621
-
-
Tischler, M.E.1
Desautels, M.2
Goldberg, A.L.3
-
30
-
-
2942726155
-
The ins and outs of FoxO shuttling: Mechanisms of FoxO translocation and transcriptional regulation
-
DOI 10.1042/BJ20040167
-
Van der Heide LP, Hoekman MF, Smidt MP. The ins and outs of FoxO shuttling: mechanisms of FoxO translocation and transcriptional regulation. Biochem J 380:297-309, 2004. (Pubitemid 38788101)
-
(2004)
Biochemical Journal
, vol.380
, Issue.2
, pp. 297-309
-
-
Van Der Heide, L.P.1
Hoekman, M.F.M.2
Smidt, M.P.3
-
31
-
-
0035850407
-
Basal muscle amino acid kinetics and protein synthesis in healthy young and older men
-
Volpi E, Sheffield-Moore M, Rasmussen BB, Wolfe RR. Basal muscle amino acid kinetics and protein synthesis in healthy young and older men. JAMA 286:1206-1212, 2001. (Pubitemid 33015550)
-
(2001)
Journal of the American Medical Association
, vol.286
, Issue.10
, pp. 1206-1212
-
-
Volpi, E.1
Sheffield-Moore, M.2
Rasmussen, B.B.3
Wolfe, R.R.4
-
32
-
-
70350647205
-
Blunting of insulin inhibition of proteolysis in legs of older subjects may contribute to age-related sarcopenia
-
Wilkes EA, Selby AL, Atherton PJ, Patel R, Rankin D, Smith K, Rennie MJ. Blunting of insulin inhibition of proteolysis in legs of older subjects may contribute to age-related sarcopenia. Am J Clin Nutr 90:1343-1350, 2009.
-
(2009)
Am J Clin Nutr
, vol.90
, pp. 1343-1350
-
-
Wilkes, E.A.1
Selby, A.L.2
Atherton, P.J.3
Patel, R.4
Rankin, D.5
Smith, K.6
Rennie, M.J.7
-
33
-
-
75049085555
-
Skeletal muscle autophagy and apoptosis during aging: Effects of calorie restriction and life-long exercise
-
Wohlgemuth SE, Seo AY, Marzetti E, Lees HA, Leeuwenburgh C. Skeletal muscle autophagy and apoptosis during aging: effects of calorie restriction and life-long exercise. Exp Gerontol 45:138-148.
-
Exp Gerontol
, vol.45
, pp. 138-148
-
-
Wohlgemuth, S.E.1
Seo, A.Y.2
Marzetti, E.3
Lees, H.A.4
Leeuwenburgh, C.5
-
34
-
-
36448968532
-
FoxO3 Coordinately Activates Protein Degradation by the Autophagic/Lysosomal and Proteasomal Pathways in Atrophying Muscle Cells
-
DOI 10.1016/j.cmet.2007.11.004, PII S1550413107003397
-
Zhao J, Brault JJ, Schild A, Cao P, Sandri M, Schiaffino S, Lecker SH, Goldberg AL. FoxO3 coordinately activates protein degradation by the autophagic/lysosomal and proteasomal pathways in atrophying muscle cells. Cell Metab 6:472-483, 2007. (Pubitemid 350163056)
-
(2007)
Cell Metabolism
, vol.6
, Issue.6
, pp. 472-483
-
-
Zhao, J.1
Brault, J.J.2
Schild, A.3
Cao, P.4
Sandri, M.5
Schiaffino, S.6
Lecker, S.H.7
Goldberg, A.L.8
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