Ryanodine receptor oxidation causes intracellular calcium leak and muscle weakness in aging

Cell Metabolism

Volumn 14, Issue 2, 2011, Pages 196-207

  Andersson, Daniel C ^a   Betzenhauser, Matthew J ^a   Reiken, Steven ^a   Meli, Albano C ^a   Umanskaya, Alisa ^a   Xie, Wenjun ^a   Shiomi, Takayuki ^a   Zalk, Ran ^a   Lacampagne, Alain ^b   Marks, Andrew R ^a  

^a Columbia University ^*  (United States)

^b UNIV MONTPELLIER   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM ION; CALSTABIN1; CYSTEINE; PROTEIN SUBUNIT; REACTIVE OXYGEN METABOLITE; RYANODINE RECEPTOR 1; UNCLASSIFIED DRUG;

AGING; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CALCIUM CELL LEVEL; CALCIUM TRANSPORT; CONTROLLED STUDY; EXERCISE; MOUSE; MUSCLE FORCE; MUSCLE MASS; MUSCLE TETANIC CONTRACTION; MUSCLE WEAKNESS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; SKELETAL MUSCLE;

AGING; ANIMALS; CALCIUM; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; MITOCHONDRIA; MOTOR ACTIVITY; MUSCLE CONTRACTION; MUSCLE WEAKNESS; MUSCLE, SKELETAL; OXIDATION-REDUCTION; OXIDATIVE STRESS; REACTIVE OXYGEN SPECIES; RYANODINE RECEPTOR CALCIUM RELEASE CHANNEL; SARCOPENIA; TACROLIMUS BINDING PROTEINS; THIAZEPINES;

MUS; RODENTIA;

EID: 79960940824     PISSN: 15504131     EISSN: 19327420     Source Type: Journal    
DOI: 10.1016/j.cmet.2011.05.014     Document Type: Article

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