Testosterone supplementation reverses sarcopenia in aging through regulation of myostatin, c-Jun NH2-terminal kinase, Notch, and Akt signaling pathways

Endocrinology

Volumn 151, Issue 2, 2010, Pages 628-638

  Kovacheva, Ekaterina L ^a   Sinha Hikim, Amiya P ^b,c   Shen, Ruoqing ^a   Sinha, Indranil ^d   Sinha Hikim, Indrani ^a  

^a CHARLES R DREW UNIVERSITY OF MEDICINE AND SCIENCE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c LOS ANGELES BIOMEDICAL RESEARCH INSTITUTE   (United States)

^d BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE INHIBITOR 1A; GLUCOSE 6 PHOSPHATE DEHYDROGENASE; GONADORELIN ANTAGONIST; MITOGEN ACTIVATED PROTEIN KINASE P38; MYOSTATIN; NOTCH RECEPTOR; PROTEIN KINASE B; STRESS ACTIVATED PROTEIN KINASE; TESTOSTERONE;

AGE DISTRIBUTION; AGED; AGING; ANDROGEN THERAPY; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CELL METABOLISM; CELL STIMULATION; CELL SURVIVAL; CONTROLLED STUDY; DISEASE MODEL; DOSE RESPONSE; ENZYME ACTIVATION; ENZYME REGULATION; FAST MUSCLE FIBER; GASTROCNEMIUS MUSCLE; GROWTH REGULATION; HORMONE ACTION; MALE; MOUSE; MUSCLE ATROPHY; MUSCLE CELL; MUSCLE GROWTH; MUSCLE LEVEL; MUSCLE MASS; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN CONTENT; SIGNAL TRANSDUCTION; SLOW MUSCLE FIBER; TESTOSTERONE BLOOD LEVEL; TESTOSTERONE SYNTHESIS;

AGING; ANIMALS; APOPTOSIS; ENZYME ACTIVATION; HUMANS; HYPERTROPHY; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MALE; MICE; MICE, INBRED C57BL; MUSCLE FIBERS, SKELETAL; MUSCLE, SKELETAL; MYOSTATIN; ORGAN SIZE; SARCOPENIA; TESTOSTERONE;

EID: 74949086718     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2009-1177     Document Type: Article

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