Amyloid precursor protein (app) mediated regulation of ganglioside homeostasis linking alzheimer's disease pathology with ganglioside metabolism

PLoS ONE

Volumn 7, Issue 3, 2012, Pages

  Grimm, Marcus O W ^a   Zinser, Eva G ^a   Grösgen, Sven ^a   Hundsdörfer, Benjamin ^a   Rothhaar, Tatjana L ^a   Burg, Verena K ^a   Kaestner, Lars ^a   Bayer, Thomas A ^b   Lipp, Peter ^a   Müller, Ulrike ^c   Grimm, Heike S ^a   Hartmann, Tobias ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b UNIVERSITY OF GÖTTINGEN   (Germany)

^c UNIVERSITY OF HEIDELBERG   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; GANGLIOSIDE; GANGLIOSIDE GD3 SYNTHASE; GANGLIOSIDE GM3; PROTEIN FE65; SYNTHETASE; UNCLASSIFIED DRUG; ALPHA N ACETYLNEURAMINATE ALPHA 2,8 SIALYLTRANSFERASE; ALPHA-N-ACETYLNEURAMINATE ALPHA-2,8-SIALYLTRANSFERASE; PRESENILIN 1; PRESENILIN 2; SIALYLTRANSFERASE; SMALL INTERFERING RNA;

ALZHEIMER DISEASE; ANIMAL CELL; ARTICLE; COMPLEX FORMATION; CONTROLLED STUDY; DELETION MUTANT; DISEASE ASSOCIATION; EMBRYO; ENZYME ACTIVITY; ENZYME METABOLISM; ENZYME REGULATION; ENZYME SUBSTRATE COMPLEX; FEEDBACK SYSTEM; GENE; GENE SILENCING; GENE TARGETING; HOMEOSTASIS; LIPID METABOLISM; MOUSE; NEUROBLASTOMA CELL; NEUROPATHOLOGY; NONHUMAN; PRESENILIN 1 GENE; PRESENILIN 2 GENE; PROTEIN ANALYSIS; PROTEIN BINDING; PROTEIN CLEAVAGE; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN LIPID INTERACTION; PROTEIN PROCESSING; PROTEIN SECRETION; PROTEIN SYNTHESIS; REGULATORY MECHANISM; TRANSCRIPTION REGULATION; TRANSCRIPTION TERMINATION; ANIMAL; CELL LINE; CELL STRAIN COS1; CERCOPITHECUS; DRUG ANTAGONISM; GENETICS; IMMUNOPRECIPITATION; METABOLISM; PATHOLOGY; RNA INTERFERENCE;

ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; CELL LINE; CERCOPITHECUS AETHIOPS; COS CELLS; GANGLIOSIDES; HOMEOSTASIS; IMMUNOPRECIPITATION; MICE; PRESENILIN-1; PRESENILIN-2; PROTEIN BINDING; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIALYLTRANSFERASES;

EID: 84859038034     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0034095     Document Type: Article

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