-
1
-
-
0037024360
-
Identification of G protein-coupled receptor genes from the human genome sequence
-
DOI 10.1016/S0014-5793(02)02775-8, PII S0014579302027758
-
S. Takeda Identification of G protein-coupled receptor genes from the human genome sequence FEBS Lett. 520 2002 97 101 (Pubitemid 34607281)
-
(2002)
FEBS Letters
, vol.520
, Issue.1-3
, pp. 97-101
-
-
Takeda, S.1
Kadowaki, S.2
Haga, T.3
Takaesu, H.4
Mitaku, S.5
-
3
-
-
17644402459
-
Transduction of receptor signals by beta-arrestins
-
R.J. Lefkowitz, and S.K. Shenoy Transduction of receptor signals by beta-arrestins Science 308 2005 512 517
-
(2005)
Science
, vol.308
, pp. 512-517
-
-
Lefkowitz, R.J.1
Shenoy, S.K.2
-
5
-
-
0242721361
-
Multifaceted roles of β-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling
-
DOI 10.1042/BJ20031076
-
S.K. Shenoy, and R.J. Lefkowitz Multifaceted roles of beta-arrestins in the regulation of seven-membrane-spanning receptor trafficking and signalling Biochem. J. 375 2003 503 515 (Pubitemid 37433499)
-
(2003)
Biochemical Journal
, vol.375
, Issue.3
, pp. 503-515
-
-
Shenoy, S.K.1
Lefkowitz, R.J.2
-
6
-
-
0030593035
-
Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization
-
S.S. Ferguson Role of beta-arrestin in mediating agonist-promoted G protein-coupled receptor internalization Science 271 1996 363 366
-
(1996)
Science
, vol.271
, pp. 363-366
-
-
Ferguson, S.S.1
-
7
-
-
0029770657
-
Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor
-
O.B. Goodman Jr. Beta-arrestin acts as a clathrin adaptor in endocytosis of the beta2-adrenergic receptor Nature 383 1996 447 450
-
(1996)
Nature
, vol.383
, pp. 447-450
-
-
Goodman, Jr.O.B.1
-
8
-
-
80052038573
-
Beta-arrestin-mediated receptor trafficking and signal transduction
-
S.K. Shenoy, and R.J. Lefkowitz Beta-arrestin-mediated receptor trafficking and signal transduction Trends Pharmacol. Sci. 32 2011 521 533
-
(2011)
Trends Pharmacol. Sci.
, vol.32
, pp. 521-533
-
-
Shenoy, S.K.1
Lefkowitz, R.J.2
-
9
-
-
33947585981
-
Phosphorylation-independent attenuation of GPCR signalling
-
DOI 10.1016/j.tips.2007.02.008, PII S016561470700051X
-
S.S. Ferguson Phosphorylation-independent attenuation of GPCR signalling Trends Pharmacol. Sci. 28 2007 173 179 (Pubitemid 46483720)
-
(2007)
Trends in Pharmacological Sciences
, vol.28
, Issue.4
, pp. 173-179
-
-
Ferguson, S.S.G.1
-
10
-
-
77952840083
-
The complex G protein-coupled receptor kinase 2 (GRK2) interactome unveils new physiopathological targets
-
P. Penela The complex G protein-coupled receptor kinase 2 (GRK2) interactome unveils new physiopathological targets Br. J. Pharmacol. 160 2010 821 832
-
(2010)
Br. J. Pharmacol.
, vol.160
, pp. 821-832
-
-
Penela, P.1
-
11
-
-
33947375174
-
Physiological roles of G protein-coupled receptor kinases and arrestins
-
DOI 10.1146/annurev.physiol.69.022405.154731
-
R.T. Premont, and R.R. Gainetdinov Physiological roles of G protein-coupled receptor kinases and arrestins Annu. Rev. Physiol. 69 2007 511 534 (Pubitemid 46457653)
-
(2007)
Annual Review of Physiology
, vol.69
, pp. 511-534
-
-
Premont, R.T.1
Gainetdinov, R.R.2
-
12
-
-
33646162635
-
GRKs and beta-arrestins: Roles in receptor silencing, trafficking and signaling
-
E. Reiter, and R.J. Lefkowitz GRKs and beta-arrestins: roles in receptor silencing, trafficking and signaling Trends Endocrinol. Metab. 17 2006 159 165
-
(2006)
Trends Endocrinol. Metab.
, vol.17
, pp. 159-165
-
-
Reiter, E.1
Lefkowitz, R.J.2
-
13
-
-
33947424008
-
The G protein-coupled receptor kinase (GRK) interactome: Role of GRKs in GPCR regulation and signaling
-
DOI 10.1016/j.bbamem.2006.09.019, PII S0005273606003774
-
C. Ribas The G protein-coupled receptor kinase (GRK) interactome: role of GRKs in GPCR regulation and signaling Biochim. Biophys. Acta 1768 2007 913 922 (Pubitemid 46452540)
-
(2007)
Biochimica et Biophysica Acta - Biomembranes
, vol.1768
, Issue.4
, pp. 913-922
-
-
Ribas, C.1
Penela, P.2
Murga, C.3
Salcedo, A.4
Garcia-Hoz, C.5
Jurado-Pueyo, M.6
Aymerich, I.7
Mayor Jr., F.8
-
14
-
-
79959804711
-
Sonic Hedgehog dependent phosphorylation by CK1alpha and GRK2 is required for ciliary accumulation and activation of Smoothened
-
Y. Chen Sonic Hedgehog dependent phosphorylation by CK1alpha and GRK2 is required for ciliary accumulation and activation of Smoothened PLoS Biol. 9 2011 e1001083
-
(2011)
PLoS Biol.
, vol.9
, pp. 1001083
-
-
Chen, Y.1
-
15
-
-
79961010813
-
Growth arrest specific 8 (Gas8) and G protein-coupled receptor kinase 2 (GRK2) cooperate in the control of Smoothened signaling
-
T. Evron Growth arrest specific 8 (Gas8) and G protein-coupled receptor kinase 2 (GRK2) cooperate in the control of Smoothened signaling J. Biol. Chem. 286 2011 27676 27686
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 27676-27686
-
-
Evron, T.1
-
16
-
-
33749590571
-
Smoothened signal transduction is promoted by G protein-coupled receptor kinase 2
-
DOI 10.1128/MCB.00546-06
-
A.R. Meloni Smoothened signal transduction is promoted by G protein-coupled receptor kinase 2 Mol. Cell. Biol. 26 2006 7550 7560 (Pubitemid 44547705)
-
(2006)
Molecular and Cellular Biology
, vol.26
, Issue.20
, pp. 7550-7560
-
-
Meloni, A.R.1
Fralish, G.B.2
Kelly, P.3
Salahpour, A.4
Chen, J.K.5
Wechsler-Reya, R.J.6
Lefkowitz, R.J.7
Caron, M.G.8
-
17
-
-
59349091148
-
Smoothened signaling in vertebrates is facilitated by a G protein-coupled receptor kinase
-
M. Philipp Smoothened signaling in vertebrates is facilitated by a G protein-coupled receptor kinase Mol. Biol. Cell 19 2008 5478 5489
-
(2008)
Mol. Biol. Cell
, vol.19
, pp. 5478-5489
-
-
Philipp, M.1
-
18
-
-
0033607326
-
q/11 by an RGS domain in the G protein-coupled receptor kinase, GRK2
-
C.V. Carman Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2 J. Biol. Chem. 274 1999 34483 34492 (Pubitemid 129511796)
-
(1999)
Journal of Biological Chemistry
, vol.274
, Issue.48
, pp. 34483-34492
-
-
Carman, C.V.1
Parent, J.-L.2
Day, P.3
Pronin, A.N.4
Sternweis, P.M.5
Wedegaertner, P.B.6
Gilman, A.G.7
Benovic, J.L.8
Kozasat, T.9
-
19
-
-
0034111099
-
Selective regulation of Gq signaling by G protein-coupled receptor kinase 2: Direct interaction of kinase N terminus with activated G(αq)
-
M. Sallese Selective regulation of Gq signaling by G protein-coupled receptor kinase 2: direct interaction of kinase N terminus with activated galphaq Mol. Pharmacol. 57 2000 826 831 (Pubitemid 30183726)
-
(2000)
Molecular Pharmacology
, vol.57
, Issue.4
, pp. 826-831
-
-
Sallese, M.1
Mariggio, S.2
D'Urbano, E.3
Iacovelli, L.4
De Blasi, A.5
-
20
-
-
80053089071
-
Heterotrimeric G protein beta1gamma2 subunits change orientation upon complex formation with G protein-coupled receptor kinase 2 (GRK2) on a model membrane
-
A.P. Boughton Heterotrimeric G protein beta1gamma2 subunits change orientation upon complex formation with G protein-coupled receptor kinase 2 (GRK2) on a model membrane Proc. Natl. Acad. Sci. U.S.A. 108 2011 E667 E673
-
(2011)
Proc. Natl. Acad. Sci. U.S.A.
, vol.108
-
-
Boughton, A.P.1
-
22
-
-
79953192547
-
Differential G-protein-coupled receptor phosphorylation provides evidence for a signaling bar code
-
A.J. Butcher Differential G-protein-coupled receptor phosphorylation provides evidence for a signaling bar code J. Biol. Chem. 286 2011 11506 11518
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 11506-11518
-
-
Butcher, A.J.1
-
23
-
-
80051616441
-
Distinct phosphorylation sites on the {beta}2-adrenergic receptor establish a barcode that encodes differential functions of {beta}-arrestin
-
K.N. Nobles Distinct phosphorylation sites on the {beta}2-adrenergic receptor establish a barcode that encodes differential functions of {beta}-arrestin Sci. Signal. 4 2011 ra51
-
(2011)
Sci. Signal.
, vol.4
, pp. 51
-
-
Nobles, K.N.1
-
24
-
-
0346874333
-
Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2
-
DOI 10.1038/nature02158
-
K. Lorenz Protein kinase C switches the Raf kinase inhibitor from Raf-1 to GRK-2 Nature 426 2003 574 579 (Pubitemid 37522645)
-
(2003)
Nature
, vol.426
, Issue.6966
, pp. 574-579
-
-
Lorenz, K.1
Lohse, M.J.2
Quitterer, U.3
-
25
-
-
0035375104
-
Agonist-dependent recruitment of phosphoinositide 3-kinase to the membrane by beta-adrenergic receptor kinase 1. A role in receptor sequestration
-
S.V. Naga Prasad Agonist-dependent recruitment of phosphoinositide 3-kinase to the membrane by beta-adrenergic receptor kinase 1. A role in receptor sequestration J. Biol. Chem. 276 2001 18953 18959
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18953-18959
-
-
Naga Prasad, S.V.1
-
27
-
-
19644397920
-
Restoration of β-adrenergic receptor signaling and contractile function in heart failure by disruption of the βARKl/phosphoinositide 3-kinase complex
-
DOI 10.1161/CIRCULATIONAHA.104.508796
-
C. Perrino Restoration of beta-adrenergic receptor signaling and contractile function in heart failure by disruption of the betaARK1/ phosphoinositide 3-kinase complex Circulation 111 2005 2579 2587 (Pubitemid 40740856)
-
(2005)
Circulation
, vol.111
, Issue.20
, pp. 2579-2587
-
-
Perrino, C.1
Prasad, S.V.N.2
Schroder, J.N.3
Hata, J.A.4
Milano, C.5
Rockman, H.A.6
-
28
-
-
0041022398
-
β-adrenergic receptor kinase (GRK2) colocalizes with β-adrenergic receptors during agonist-induced receptor internalization
-
DOI 10.1074/jbc.272.15.9601
-
A. Ruiz-Gomez, and F. Mayor Jr. Beta-adrenergic receptor kinase (GRK2) colocalizes with beta-adrenergic receptors during agonist-induced receptor internalization J. Biol. Chem. 272 1997 9601 9604 (Pubitemid 27171614)
-
(1997)
Journal of Biological Chemistry
, vol.272
, Issue.15
, pp. 9601-9604
-
-
Ruiz-Gomez, A.1
Mayor Jr., F.2
-
29
-
-
0035980124
-
Clathrin box in G protein-coupled receptor kinase 2
-
T. Shiina Clathrin box in G protein-coupled receptor kinase 2 J. Biol. Chem. 276 2001 33019 33026
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 33019-33026
-
-
Shiina, T.1
-
30
-
-
79960710835
-
Regulation of c3a receptor signaling in human mast cells by G protein coupled receptor kinases
-
Q. Guo Regulation of c3a receptor signaling in human mast cells by G protein coupled receptor kinases PLoS ONE 6 2011 e22559
-
(2011)
PLoS ONE
, vol.6
, pp. 22559
-
-
Guo, Q.1
-
31
-
-
13444291851
-
Functional antagonism of different G protein-coupled receptor kinases for β-arrestin-mediated angiotensin II receptor signaling
-
DOI 10.1073/pnas.0409532102
-
J. Kim Functional antagonism of different G protein-coupled receptor kinases for beta-arrestin-mediated angiotensin II receptor signaling Proc. Natl. Acad. Sci. U.S.A. 102 2005 1442 1447 (Pubitemid 40209189)
-
(2005)
Proceedings of the National Academy of Sciences of the United States of America
, vol.102
, Issue.5
, pp. 1442-1447
-
-
Kim, J.1
Ahn, S.2
Ren, X.-R.3
Whalen, E.J.4
Reiter, E.5
Wei, H.6
Lefkowitz, R.J.7
-
32
-
-
13444270337
-
Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor
-
X.R. Ren Different G protein-coupled receptor kinases govern G protein and beta-arrestin-mediated signaling of V2 vasopressin receptor Proc. Natl. Acad. Sci. U.S.A. 102 2005 1448 1453
-
(2005)
Proc. Natl. Acad. Sci. U.S.A.
, vol.102
, pp. 1448-1453
-
-
Ren, X.R.1
-
33
-
-
0033973475
-
Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity
-
DOI 10.1073/pnas.97.3.1119
-
A. Claing Multiple endocytic pathways of G protein-coupled receptors delineated by GIT1 sensitivity Proc. Natl. Acad. Sci. U.S.A. 97 2000 1119 1124 (Pubitemid 30080822)
-
(2000)
Proceedings of the National Academy of Sciences of the United States of America
, vol.97
, Issue.3
, pp. 1119-1124
-
-
Claing, A.1
Perry, S.J.2
Achiriloaie, M.3
Walker, J.K.L.4
Albanesi, J.P.5
Lefkowitz, R.J.6
Premont, R.T.7
-
34
-
-
0032564277
-
2-Adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein
-
DOI 10.1073/pnas.95.24.14082
-
R.T. Premont Beta2-adrenergic receptor regulation by GIT1, a G protein-coupled receptor kinase-associated ADP ribosylation factor GTPase-activating protein Proc. Natl. Acad. Sci. U.S.A. 95 1998 14082 14087 (Pubitemid 28549324)
-
(1998)
Proceedings of the National Academy of Sciences of the United States of America
, vol.95
, Issue.24
, pp. 14082-14087
-
-
Premont, R.T.1
Claing, A.2
Vitale, N.3
Freeman, J.L.R.4
Pitcher, J.A.5
Patton, W.A.6
Moss, J.7
Vaughan, M.8
Lefkowitz, R.J.9
-
35
-
-
0034698059
-
The GIT family of ADP-ribosylation factor GTPase-activating proteins: Functional diversity of GIT2 through alternative splicing
-
DOI 10.1074/jbc.275.29.22373
-
R.T. Premont The GIT family of ADP-ribosylation factor GTPase-activating proteins. Functional diversity of GIT2 through alternative splicing J. Biol. Chem. 275 2000 22373 22380 (Pubitemid 30621823)
-
(2000)
Journal of Biological Chemistry
, vol.275
, Issue.29
, pp. 22373-22380
-
-
Premont, R.T.1
Claing, A.2
Vitale, N.3
Perry, S.J.4
Lefkowitz, R.J.5
-
36
-
-
0042029729
-
Agonist-induced formation of opioid receptor-G protein-coupled receptor kinase (GRK)-Gβγ complex on membrane is required for GRK2 function in vivo
-
DOI 10.1074/jbc.M302385200
-
J. Li Agonist-induced formation of opioid receptor-G protein-coupled receptor kinase (GRK)-G beta gamma complex on membrane is required for GRK2 function in vivo J. Biol. Chem. 278 2003 30219 30226 (Pubitemid 36962416)
-
(2003)
Journal of Biological Chemistry
, vol.278
, Issue.32
, pp. 30219-30226
-
-
Li, J.1
Xiang, B.2
Su, W.3
Zhang, X.4
Huang, Y.5
Ma, L.6
-
37
-
-
0026803164
-
Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors
-
J.A. Pitcher Role of beta gamma subunits of G proteins in targeting the beta-adrenergic receptor kinase to membrane-bound receptors Science 257 1992 1264 1267
-
(1992)
Science
, vol.257
, pp. 1264-1267
-
-
Pitcher, J.A.1
-
38
-
-
79251506646
-
Nonenzymatic rapid control of GIRK channel function by a G protein-coupled receptor kinase
-
A. Raveh Nonenzymatic rapid control of GIRK channel function by a G protein-coupled receptor kinase Cell 143 2010 750 760
-
(2010)
Cell
, vol.143
, pp. 750-760
-
-
Raveh, A.1
-
39
-
-
69949181911
-
Phosphorylation-independent regulation of metabotropic glutamate receptor 5 desensitization and internalization by G protein-coupled receptor kinase 2 in neurons
-
F.M. Ribeiro Phosphorylation-independent regulation of metabotropic glutamate receptor 5 desensitization and internalization by G protein-coupled receptor kinase 2 in neurons J. Biol. Chem. 284 2009 23444 23453
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 23444-23453
-
-
Ribeiro, F.M.1
-
40
-
-
3543038233
-
GRK2 is an endogenous protein inhibitor of the insulin signaling pathway for glucose transport stimulation
-
DOI 10.1038/sj.emboj.7600297
-
I. Usui GRK2 is an endogenous protein inhibitor of the insulin signaling pathway for glucose transport stimulation EMBO J. 23 2004 2821 2829 (Pubitemid 39013554)
-
(2004)
EMBO Journal
, vol.23
, Issue.14
, pp. 2821-2829
-
-
Usui, I.1
Imamura, T.2
Satoh, H.3
Huang, J.4
Babendure, J.L.5
Hupfeld, C.J.6
Olefsky, J.M.7
-
41
-
-
27644433164
-
G protein-coupled receptor kinase 2 mediates endothelin-1-induced insulin resistance via the inhibition of both Gαq/11 and insulin receptor substrate-1 pathways in 3T3-L1 adipocytes
-
DOI 10.1210/me.2004-0429
-
I. Usui G protein-coupled receptor kinase 2 mediates endothelin-1-induced insulin resistance via the inhibition of both Galphaq/11 and insulin receptor substrate-1 pathways in 3T3-L1 adipocytes Mol. Endocrinol. 19 2005 2760 2768 (Pubitemid 41577248)
-
(2005)
Molecular Endocrinology
, vol.19
, Issue.11
, pp. 2760-2768
-
-
Usui, I.1
Imamura, T.2
Babendure, J.L.3
Satoh, H.4
Lu, J.-C.5
Hupfeld, C.J.6
Olefsky, J.M.7
-
42
-
-
80051697652
-
Roles of phosphorylation-dependent and -independent mechanisms in the regulation of histamine H2 receptor by G protein-coupled receptor kinase 2
-
N. Fernandez Roles of phosphorylation-dependent and -independent mechanisms in the regulation of histamine H2 receptor by G protein-coupled receptor kinase 2 J. Biol. Chem. 286 2011 28697 28706
-
(2011)
J. Biol. Chem.
, vol.286
, pp. 28697-28706
-
-
Fernandez, N.1
-
43
-
-
64849098229
-
Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK
-
A.I. Aziziyeh Dual regulation of lysophosphatidic acid (LPA1) receptor signalling by Ral and GRK Cell Signal. 21 2009 1207 1217
-
(2009)
Cell Signal.
, vol.21
, pp. 1207-1217
-
-
Aziziyeh, A.I.1
-
44
-
-
80053345544
-
GRK2-dependent S1PR1 desensitization is required for lymphocytes to overcome their attraction to blood
-
T.I. Arnon GRK2-dependent S1PR1 desensitization is required for lymphocytes to overcome their attraction to blood Science 333 2011 1898 1903
-
(2011)
Science
, vol.333
, pp. 1898-1903
-
-
Arnon, T.I.1
-
45
-
-
42449152447
-
G protein-coupled receptor kinase 2 positively regulates epithelial cell migration
-
DOI 10.1038/emboj.2008.55, PII EMBOJ200855
-
P. Penela G protein-coupled receptor kinase 2 positively regulates epithelial cell migration EMBO J. 27 2008 1206 1218 (Pubitemid 351574750)
-
(2008)
EMBO Journal
, vol.27
, Issue.8
, pp. 1206-1218
-
-
Penela, P.1
Ribas, C.2
Aymerich, I.3
Eijkelkamp, N.4
Barreiro, O.5
Heijnen, C.J.6
Kavelaars, A.7
Sanchez-Madrid, F.8
Mayor Jr., F.9
-
46
-
-
67049101075
-
New roles of G protein-coupled receptor kinase 2 (GRK2) in cell migration
-
P. Penela New roles of G protein-coupled receptor kinase 2 (GRK2) in cell migration Cell Adh. Migr. 3 2009 19 23
-
(2009)
Cell Adh. Migr.
, vol.3
, pp. 19-23
-
-
Penela, P.1
-
47
-
-
24744444714
-
A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension
-
DOI 10.1038/nm1289
-
S. Liu A crucial role for GRK2 in regulation of endothelial cell nitric oxide synthase function in portal hypertension Nat. Med. 11 2005 952 958 (Pubitemid 41294440)
-
(2005)
Nature Medicine
, vol.11
, Issue.9
, pp. 952-958
-
-
Liu, S.1
Premont, R.T.2
Kontos, C.D.3
Zhu, S.4
Rockey, D.C.5
-
48
-
-
30044434455
-
G protein-coupled receptor kinase 2 negatively regulates chemokine signaling at a level downstream from G protein subunits
-
DOI 10.1091/mbc.E05-05-0399
-
M.C. Jimenez-Sainz G protein-coupled receptor kinase 2 negatively regulates chemokine signaling at a level downstream from G protein subunits Mol. Biol. Cell 17 2006 25 31 (Pubitemid 43049458)
-
(2006)
Molecular Biology of the Cell
, vol.17
, Issue.1
, pp. 25-31
-
-
Jimenez-Sainz, M.C.1
Murga, C.2
Kavelaars, A.3
Jurado-Pueyo, M.4
Krakstad, B.F.5
Heijnen, C.J.6
Mayor Jr., F.7
Aragay, A.M.8
-
50
-
-
77957193666
-
Low nociceptor GRK2 prolongs prostaglandin E2 hyperalgesia via biased cAMP signaling to Epac/Rap1, protein kinase Cepsilon, and MEK/ERK
-
N. Eijkelkamp Low nociceptor GRK2 prolongs prostaglandin E2 hyperalgesia via biased cAMP signaling to Epac/Rap1, protein kinase Cepsilon, and MEK/ERK J. Neurosci. 30 2010 12806 12815
-
(2010)
J. Neurosci.
, vol.30
, pp. 12806-12815
-
-
Eijkelkamp, N.1
-
51
-
-
76649125850
-
GRK2: A novel cell-specific regulator of severity and duration of inflammatory pain
-
N. Eijkelkamp GRK2: a novel cell-specific regulator of severity and duration of inflammatory pain J. Neurosci. 30 2010 2138 2149
-
(2010)
J. Neurosci.
, vol.30
, pp. 2138-2149
-
-
Eijkelkamp, N.1
-
52
-
-
37349018685
-
IL-1β signaling is required for mechanical allodynia induced by nerve injury and for the ensuing reduction in spinal cord neuronal GRK2
-
DOI 10.1016/j.bbi.2007.07.009, PII S0889159107001675
-
W. Kleibeuker IL-1 beta signaling is required for mechanical allodynia induced by nerve injury and for the ensuing reduction in spinal cord neuronal GRK2 Brain Behav. Immun. 22 2008 200 208 (Pubitemid 350299802)
-
(2008)
Brain, Behavior, and Immunity
, vol.22
, Issue.2
, pp. 200-208
-
-
Kleibeuker, W.1
Gabay, E.2
Kavelaars, A.3
Zijlstra, J.4
Wolf, G.5
Ziv, N.6
Yirmiya, R.7
Shavit, Y.8
Tal, M.9
Heijnen, C.J.10
-
53
-
-
0032493759
-
Binding and phosphorylation of tubulin by G protein-coupled receptor kinases
-
DOI 10.1074/jbc.273.32.20308
-
C.V. Carman Binding and phosphorylation of tubulin by G protein-coupled receptor kinases J. Biol. Chem. 273 1998 20308 20316 (Pubitemid 28377594)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.32
, pp. 20308-20316
-
-
Carman, C.V.1
Som, T.2
Kim, C.M.3
Benovic, J.L.4
-
54
-
-
0032528248
-
GTP-binding-protein-coupled receptor kinase 2 (GRK2) binds and phosphorylates tubulin
-
DOI 10.1046/j.1432-1327.1998.2550363.x
-
K. Haga GTP-binding-protein-coupled receptor kinase 2 (GRK2) binds and phosphorylates tubulin Eur. J. Biochem. 255 1998 363 368 (Pubitemid 28340244)
-
(1998)
European Journal of Biochemistry
, vol.255
, Issue.2
, pp. 363-368
-
-
Haga, K.1
Ogawa, H.2
Haga, T.3
Murofushi, H.4
-
55
-
-
15444340119
-
The G protein-coupled receptor kinase 2 is a microtubule-associated protein kinase that phosphorylates tubulin
-
DOI 10.1074/jbc.273.20.12316
-
J.A. Pitcher The G protein-coupled receptor kinase 2 is a microtubule-associated protein kinase that phosphorylates tubulin J. Biol. Chem. 273 1998 12316 12324 (Pubitemid 28240600)
-
(1998)
Journal of Biological Chemistry
, vol.273
, Issue.20
, pp. 12316-12324
-
-
Pitcher, J.A.1
Hall, R.A.2
Daaka, Y.3
Zhang, J.4
Ferguson, S.S.G.5
Hester, S.6
Miller, S.7
Caron, M.G.8
Lefkowitz, R.J.9
Barak, L.S.10
-
56
-
-
0037349646
-
Identification of sites of phosphorylation by G-protein-coupled receptor kinase 2 in β-tubulin
-
DOI 10.1046/j.1432-1033.2003.03465.x
-
N. Yoshida Identification of sites of phosphorylation by G-protein-coupled receptor kinase 2 in beta-tubulin Eur. J. Biochem. 270 2003 1154 1163 (Pubitemid 36384448)
-
(2003)
European Journal of Biochemistry
, vol.270
, Issue.6
, pp. 1154-1163
-
-
Yoshida, N.1
Haga, K.2
Haga, T.3
-
57
-
-
33847246808
-
Taxol normalizes the impaired agonist-induced beta2-adrenoceptor internalization in splenocytes from GRK2+/- mice
-
A. Vroon Taxol normalizes the impaired agonist-induced beta2-adrenoceptor internalization in splenocytes from GRK2+/- mice Eur. J. Pharmacol. 560 2007 9 16
-
(2007)
Eur. J. Pharmacol.
, vol.560
, pp. 9-16
-
-
Vroon, A.1
-
58
-
-
77649275413
-
G protein-coupled receptor kinase 2 activates radixin, regulating membrane protrusion and motility in epithelial cells
-
A.W. Kahsai G protein-coupled receptor kinase 2 activates radixin, regulating membrane protrusion and motility in epithelial cells Biochim. Biophys. Acta 1803 2010 300 310
-
(2010)
Biochim. Biophys. Acta
, vol.1803
, pp. 300-310
-
-
Kahsai, A.W.1
-
59
-
-
21844467495
-
G protein-coupled receptor kinase 2-mediated phosphorylation of Ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton
-
DOI 10.1091/mbc.E04-10-0877
-
S.H. Cant, and J.A. Pitcher G protein-coupled receptor kinase 2-mediated phosphorylation of ezrin is required for G protein-coupled receptor-dependent reorganization of the actin cytoskeleton Mol. Biol. Cell 16 2005 3088 3099 (Pubitemid 40962582)
-
(2005)
Molecular Biology of the Cell
, vol.16
, Issue.7
, pp. 3088-3099
-
-
Cant, S.H.1
Pitcher, J.A.2
-
60
-
-
77957600228
-
G protein-coupled receptor kinase 2 plays a relevant role in insulin resistance and obesity
-
L. Garcia-Guerra G protein-coupled receptor kinase 2 plays a relevant role in insulin resistance and obesity Diabetes 59 2010 2407 2417
-
(2010)
Diabetes
, vol.59
, pp. 2407-2417
-
-
Garcia-Guerra, L.1
-
61
-
-
79955782045
-
G protein-coupled receptor kinase 2 activity impairs cardiac glucose uptake and promotes insulin resistance after myocardial ischemia
-
M. Ciccarelli G protein-coupled receptor kinase 2 activity impairs cardiac glucose uptake and promotes insulin resistance after myocardial ischemia Circulation 123 2011 1953 1962
-
(2011)
Circulation
, vol.123
, pp. 1953-1962
-
-
Ciccarelli, M.1
-
62
-
-
25144432973
-
The G protein-coupled receptor kinase-2 is a TGFβ-inducible antagonist of TGFβ signal transduction
-
DOI 10.1038/sj.emboj.7600794, PII 7600794
-
J. Ho The G protein-coupled receptor kinase-2 is a TGFbeta-inducible antagonist of TGFbeta signal transduction EMBO J. 24 2005 3247 3258 (Pubitemid 41348699)
-
(2005)
EMBO Journal
, vol.24
, Issue.18
, pp. 3247-3258
-
-
Ho, J.1
Cocolakis, E.2
Dumas, V.M.3
Posner, B.I.4
Laporte, S.A.5
Lebrun, J.-J.6
-
63
-
-
62749127825
-
TGFbeta-induced GRK2 expression attenuates AngII-regulated vascular smooth muscle cell proliferation and migration
-
J. Guo TGFbeta-induced GRK2 expression attenuates AngII-regulated vascular smooth muscle cell proliferation and migration Cell Signal. 21 2009 899 905
-
(2009)
Cell Signal.
, vol.21
, pp. 899-905
-
-
Guo, J.1
-
64
-
-
0034714204
-
Synucleins are a novel class of substrates for G protein-coupled receptor kinases
-
A.N. Pronin Synucleins are a novel class of substrates for G protein-coupled receptor kinases J. Biol. Chem. 275 2000 26515 26522
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 26515-26522
-
-
Pronin, A.N.1
-
65
-
-
57149084065
-
Molecular and cellular biology of synucleins
-
A. Surguchov Molecular and cellular biology of synucleins Int. Rev. Cell Mol. Biol. 270 2008 225 317
-
(2008)
Int. Rev. Cell Mol. Biol.
, vol.270
, pp. 225-317
-
-
Surguchov, A.1
-
66
-
-
72449146904
-
G-protein-coupled-receptor kinases mediate TNFalpha-induced NFkappaB signalling via direct interaction with and phosphorylation of IkappaBalpha
-
S. Patial G-protein-coupled-receptor kinases mediate TNFalpha-induced NFkappaB signalling via direct interaction with and phosphorylation of IkappaBalpha Biochem. J. 425 2010 169 178
-
(2010)
Biochem. J.
, vol.425
, pp. 169-178
-
-
Patial, S.1
-
67
-
-
33750218229
-
Phosphorylation of p38 by GRK2 at the Docking Groove Unveils a Novel Mechanism for Inactivating p38MAPK
-
DOI 10.1016/j.cub.2006.08.083, PII S0960982206021518
-
S. Peregrin Phosphorylation of p38 by GRK2 at the docking groove unveils a novel mechanism for inactivating p38MAPK Curr. Biol. 16 2006 2042 2047 (Pubitemid 44604449)
-
(2006)
Current Biology
, vol.16
, Issue.20
, pp. 2042-2047
-
-
Peregrin, S.1
Jurado-Pueyo, M.2
Campos, P.M.3
Sanz-Moreno, V.4
Ruiz-Gomez, A.5
Crespo, P.6
Mayor Jr., F.7
Murga, C.8
-
68
-
-
47849125977
-
Immunohistochemical detection, regulation and antiproliferative function of G-protein-coupled receptor kinase 2 in thyroid carcinomas
-
DOI 10.1677/JOE-07-0562
-
T. Metaye Immunohistochemical detection, regulation and antiproliferative function of G-protein-coupled receptor kinase 2 in thyroid carcinomas J. Endocrinol. 198 2008 101 110 (Pubitemid 352038189)
-
(2008)
Journal of Endocrinology
, vol.198
, Issue.1
, pp. 101-110
-
-
Metaye, T.1
Levillain, P.2
Kraimps, J.-L.3
Perdrisot, R.4
-
69
-
-
0033869812
-
Overexpression of G protein - Coupled receptor kinase-2 in smooth muscle cells attenuates mitogenic signaling via G protein - Coupled and platelet-derived growth factor receptors
-
K. Peppel Overexpression of G protein-coupled receptor kinase-2 in smooth muscle cells attenuates mitogenic signaling via G protein-coupled and platelet-derived growth factor receptors Circulation 102 2000 793 799 (Pubitemid 30643287)
-
(2000)
Circulation
, vol.102
, Issue.7
, pp. 793-799
-
-
Peppel, K.1
Jacobson, A.2
Huang, X.3
Murray, J.P.4
Oppermann, M.5
Freedman, N.J.6
-
70
-
-
75749118972
-
G protein-coupled receptor kinase 2 (GRK2) modulation and cell cycle progression
-
P. Penela G protein-coupled receptor kinase 2 (GRK2) modulation and cell cycle progression Proc. Natl. Acad. Sci. U.S.A. 107 2010 1118 1123
-
(2010)
Proc. Natl. Acad. Sci. U.S.A.
, vol.107
, pp. 1118-1123
-
-
Penela, P.1
-
71
-
-
84857497775
-
Growth inhibition of human hepatocellular carcinoma cells by overexpression of G protein-coupled receptor kinase 2
-
10.1002/jcp.22972
-
Z. Wei Growth inhibition of human hepatocellular carcinoma cells by overexpression of G protein-coupled receptor kinase 2 J. Cell Physiol. 2011 10.1002/jcp.22972
-
(2011)
J. Cell Physiol.
-
-
Wei, Z.1
-
72
-
-
67649836304
-
Kinase activity-independent regulation of cyclin pathway by GRK2 is essential for zebrafish early development
-
X. Jiang Kinase activity-independent regulation of cyclin pathway by GRK2 is essential for zebrafish early development Proc. Natl. Acad. Sci. U.S.A. 106 2009 10183 10188
-
(2009)
Proc. Natl. Acad. Sci. U.S.A.
, vol.106
, pp. 10183-10188
-
-
Jiang, X.1
-
73
-
-
0033558141
-
Sequestration of dopamine D2 receptors depends on coexpression of G- protein-coupled receptor kinases 2 or 5
-
DOI 10.1046/j.1432-1327.1999.00125.x
-
K. Ito Sequestration of dopamine D2 receptors depends on coexpression of G-protein-coupled receptor kinases 2 or 5 Eur. J. Biochem. 260 1999 112 119 (Pubitemid 29095701)
-
(1999)
European Journal of Biochemistry
, vol.260
, Issue.1
, pp. 112-119
-
-
Ito, K.1
Haga, T.2
Lameh, J.3
Sadee, W.4
-
76
-
-
77957797131
-
Cytoplasmic tail of D1 dopaminergic receptor differentially regulates desensitization and phosphorylation by G protein-coupled receptor kinase 2 and 3
-
K. Sedaghat, and M. Tiberi Cytoplasmic tail of D1 dopaminergic receptor differentially regulates desensitization and phosphorylation by G protein-coupled receptor kinase 2 and 3 Cell Signal. 23 2011 180 192
-
(2011)
Cell Signal.
, vol.23
, pp. 180-192
-
-
Sedaghat, K.1
Tiberi, M.2
-
77
-
-
67649321841
-
G protein-coupled receptor kinase-mediated phosphorylation regulates post-endocytic trafficking of the D2 dopamine receptor
-
Y. Namkung G protein-coupled receptor kinase-mediated phosphorylation regulates post-endocytic trafficking of the D2 dopamine receptor J. Biol. Chem. 284 2009 15038 15051
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 15038-15051
-
-
Namkung, Y.1
-
78
-
-
71749113078
-
G protein-coupled receptor kinase-2 constitutively regulates D2 dopamine receptor expression and signaling independently of receptor phosphorylation
-
Y. Namkung G protein-coupled receptor kinase-2 constitutively regulates D2 dopamine receptor expression and signaling independently of receptor phosphorylation J. Biol. Chem. 284 2009 34103 34115
-
(2009)
J. Biol. Chem.
, vol.284
, pp. 34103-34115
-
-
Namkung, Y.1
-
79
-
-
39849085956
-
Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by L-DOPA treatment
-
DOI 10.1111/j.1471-4159.2007.05104.x
-
M.R. Ahmed Altered expression and subcellular distribution of GRK subtypes in the dopamine-depleted rat basal ganglia is not normalized by l-DOPA treatment J. Neurochem. 104 2008 1622 1636 (Pubitemid 351316768)
-
(2008)
Journal of Neurochemistry
, vol.104
, Issue.6
, pp. 1622-1636
-
-
Ahmed, M.R.1
Bychkov, E.2
Gurevich, V.V.3
Benovic, J.L.4
Gurevich, E.V.5
-
80
-
-
15944407993
-
L-DOPA reverses the MPTP-induced elevation of the arrestin2 and GRK6 expression and enhanced ERK activation in monkey brain
-
DOI 10.1016/j.nbd.2004.10.005
-
E. Bezard L-DOPA reverses the MPTP-induced elevation of the arrestin2 and GRK6 expression and enhanced ERK activation in monkey brain Neurobiol. Dis. 18 2005 323 335 (Pubitemid 40431116)
-
(2005)
Neurobiology of Disease
, vol.18
, Issue.2
, pp. 323-335
-
-
Bezard, E.1
Gross, C.E.2
Qin, L.3
Gurevich, V.V.4
Benovic, J.L.5
Gurevich, E.V.6
-
81
-
-
70349114286
-
Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration
-
J.A. Schroeder Regulation of dynamin 2 and G protein-coupled receptor kinase 2 in rat nucleus accumbens during acute and repeated cocaine administration Synapse 63 2009 863 870
-
(2009)
Synapse
, vol.63
, pp. 863-870
-
-
Schroeder, J.A.1
-
82
-
-
49849098290
-
FMRP acts as a key messenger for dopamine modulation in the forebrain
-
H. Wang FMRP acts as a key messenger for dopamine modulation in the forebrain Neuron 59 2008 634 647
-
(2008)
Neuron
, vol.59
, pp. 634-647
-
-
Wang, H.1
-
83
-
-
31644442906
-
Signaling from Smo to Ci/Gli: Conservation and divergence of Hedgehog pathways from Drosophila to vertebrates
-
DOI 10.1242/dev.02169
-
D. Huangfu, and K.V. Anderson Signaling from Smo to Ci/Gli: conservation and divergence of Hedgehog pathways from Drosophila to vertebrates Development 133 2006 3 14 (Pubitemid 43169315)
-
(2006)
Development
, vol.133
, Issue.1
, pp. 3-14
-
-
Huangfu, D.1
Anderson, K.V.2
-
84
-
-
59349106501
-
Hedgehog signaling: Is Smo a G protein-coupled receptor?
-
M. Philipp, and M.G. Caron Hedgehog signaling: is Smo a G protein-coupled receptor? Curr. Biol. 19 2009 R125 R127
-
(2009)
Curr. Biol.
, vol.19
-
-
Philipp, M.1
Caron, M.G.2
-
85
-
-
11144256194
-
Activity-dependent internalization of smoothened mediated by β-Arrestin 2 and GRK2
-
DOI 10.1126/science.1104135
-
W. Chen Activity-dependent internalization of smoothened mediated by beta-arrestin 2 and GRK2 Science 306 2004 2257 2260 (Pubitemid 40024463)
-
(2004)
Science
, vol.306
, Issue.5705
, pp. 2257-2260
-
-
Chen, W.1
Ren, X.-R.2
Nelson, C.D.3
Barak, L.S.4
Chen, J.K.5
Beachy, P.A.6
De Sauvage, F.7
Lefkowitz, R.J.8
-
88
-
-
10544242967
-
Essential role of β-adrenergic receptor kinase 1 in cardiac development and function
-
DOI 10.1073/pnas.93.23.12974
-
M. Jaber Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function Proc. Natl. Acad. Sci. U.S.A. 93 1996 12974 12979 (Pubitemid 26382754)
-
(1996)
Proceedings of the National Academy of Sciences of the United States of America
, vol.93
, Issue.23
, pp. 12974-12979
-
-
Jaber, M.1
Koch, W.J.2
Rockman, H.3
Smith, B.4
Bond, R.A.5
Sulik, K.K.6
Ross Jr., J.7
Lefkowitz, R.J.8
Caron, M.G.9
Giros, B.10
-
89
-
-
33750428974
-
Cardiac-specific ablation of G-protein receptor kinase 2 redefines its roles in heart development and β-adrenergic signaling
-
DOI 10.1161/01.RES.0000247932.71270.2c, PII 0000301220061027000013
-
S.J. Matkovich Cardiac-specific ablation of G-protein receptor kinase 2 redefines its roles in heart development and beta-adrenergic signaling Circ. Res. 99 2006 996 1003 (Pubitemid 44657803)
-
(2006)
Circulation Research
, vol.99
, Issue.9
, pp. 996-1003
-
-
Matkovich, S.J.1
Diwan, A.2
Klanke, J.L.3
Hammer, D.J.4
Marreez, Y.5
Odley, A.M.6
Brunskill, E.W.7
Koch, W.J.8
Schwartz, R.J.9
Dorn II, G.W.10
-
90
-
-
77951101203
-
The primary cilium: A signalling centre during vertebrate development
-
S.C. Goetz, and K.V. Anderson The primary cilium: a signalling centre during vertebrate development Nat. Rev. Genet. 11 2010 331 344
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 331-344
-
-
Goetz, S.C.1
Anderson, K.V.2
-
91
-
-
77955426475
-
Vertebrate Hedgehog signaling: Cilia rule
-
C.W. Wilson, and D.Y. Stainier Vertebrate Hedgehog signaling: cilia rule BMC Biol. 8 2010 102
-
(2010)
BMC Biol.
, vol.8
, pp. 102
-
-
Wilson, C.W.1
Stainier, D.Y.2
-
92
-
-
46449127054
-
β-arrestin-mediated localization of smoothened to the primary cilium
-
DOI 10.1126/science.1157983
-
J.J. Kovacs {beta}-Arrestin-mediated localization of Smoothened to the primary cilium Science 320 2008 1777 1781 (Pubitemid 351931292)
-
(2008)
Science
, vol.320
, Issue.5884
, pp. 1777-1781
-
-
Kovacs, J.J.1
Whalen, E.J.2
Liu, R.3
Xiao, K.4
Kim, J.5
Chen, M.6
Wang, J.7
Chen, W.8
Lefkowitz, R.J.9
-
93
-
-
77954086015
-
Gli2a protein localization reveals a role for Iguana/DZIP1 in primary ciliogenesis and a dependence of Hedgehog signal transduction on primary cilia in the zebrafish
-
H.R. Kim Gli2a protein localization reveals a role for Iguana/DZIP1 in primary ciliogenesis and a dependence of Hedgehog signal transduction on primary cilia in the zebrafish BMC Biol. 8 2010 65
-
(2010)
BMC Biol.
, vol.8
, pp. 65
-
-
Kim, H.R.1
-
94
-
-
56649123195
-
Targeting of beta-arrestin2 to the centrosome and primary cilium: Role in cell proliferation control
-
A. Molla-Herman Targeting of beta-arrestin2 to the centrosome and primary cilium: role in cell proliferation control PLoS ONE 3 2008 e3728
-
(2008)
PLoS ONE
, vol.3
, pp. 3728
-
-
Molla-Herman, A.1
-
95
-
-
34249047067
-
Direct interaction of Gas11 with microtubules: Implications for the dynein regulatory complex
-
DOI 10.1002/cm.20196
-
J.M. Bekker Direct interaction of Gas11 with microtubules: implications for the dynein regulatory complex Cell Motil. Cytoskeleton 64 2007 461 473 (Pubitemid 46801578)
-
(2007)
Cell Motility and the Cytoskeleton
, vol.64
, Issue.6
, pp. 461-473
-
-
Bekker, J.M.1
Colantonio, J.R.2
Stephens, A.D.3
Clarke, W.T.4
King, S.J.5
Hill, K.L.6
Crosbie, R.H.7
-
96
-
-
33745827399
-
Expanding the role of the dynein regulatory complex to non-axonemal functions: Association of GAS11 with the golgi apparatus
-
DOI 10.1111/j.1600-0854.2006.00411.x
-
J.R. Colantonio Expanding the role of the dynein regulatory complex to non-axonemal functions: association of GAS11 with the Golgi apparatus Traffic 7 2006 538 548 (Pubitemid 44026752)
-
(2006)
Traffic
, vol.7
, Issue.5
, pp. 538-548
-
-
Colantonio, J.R.1
Bekker, J.M.2
Kim, S.J.3
Morrissey, K.M.4
Crosbie, R.H.5
Hill, K.L.6
-
97
-
-
58149352343
-
The dynein regulatory complex is required for ciliary motility and otolith biogenesis in the inner ear
-
J.R. Colantonio The dynein regulatory complex is required for ciliary motility and otolith biogenesis in the inner ear Nature 457 2009 205 209
-
(2009)
Nature
, vol.457
, pp. 205-209
-
-
Colantonio, J.R.1
|