-
1
-
-
0031941122
-
Reduced nitric oxide production by endothelial cells in cirrhotic rat liver: Endothelial dysfunction in portal hypertension
-
Rockey, D.C. & Chung, J.J. Reduced nitric oxide production by endothelial cells in cirrhotic rat liver: endothelial dysfunction in portal hypertension. Gastroenterology 114, 344-351 (1998).
-
(1998)
Gastroenterology
, vol.114
, pp. 344-351
-
-
Rockey, D.C.1
Chung, J.J.2
-
2
-
-
0032738990
-
Impaired endothelial nitric oxide synthase activity associated with enhanced caveolin binding in experimental cirrhosis in the rat
-
Shah, V. et al. Impaired endothelial nitric oxide synthase activity associated with enhanced caveolin binding in experimental cirrhosis in the rat. Gastroenterology 117, 1222-1228 (1999).
-
(1999)
Gastroenterology
, vol.117
, pp. 1222-1228
-
-
Shah, V.1
-
3
-
-
0034121518
-
Gene transfer of the neuronal NO synthase isoform to cirrhotic rat liver ameliorates portal hypertension
-
Yu, Q., Shao, R., Qian, H.S., George, S.E. & Rockey, D.C. Gene transfer of the neuronal NO synthase isoform to cirrhotic rat liver ameliorates portal hypertension. J. Clin. Invest. 105, 741-748 (2000).
-
(2000)
J. Clin. Invest.
, vol.105
, pp. 741-748
-
-
Yu, Q.1
Shao, R.2
Qian, H.S.3
George, S.E.4
Rockey, D.C.5
-
4
-
-
0029910141
-
Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1
-
Garcia-Cardena, G., Fan, R., Stern, D.F., Liu, J. & Sessa, W.C. Endothelial nitric oxide synthase is regulated by tyrosine phosphorylation and interacts with caveolin-1. J. Biol. Chem. 271, 27237-27240 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 27237-27240
-
-
Garcia-Cardena, G.1
Fan, R.2
Stern, D.F.3
Liu, J.4
Sessa, W.C.5
-
5
-
-
0037131346
-
Subcellular targeting and agonist-induced site-specific phosphorylation of endothelial nitric-oxide synthase
-
Gonzalez, E., Kou, R., Lin, A.J., Golan, D.E. & Michel, T. Subcellular targeting and agonist-induced site-specific phosphorylation of endothelial nitric-oxide synthase. J. Biol. Chem. 277, 39554-39560 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39554-39560
-
-
Gonzalez, E.1
Kou, R.2
Lin, A.J.3
Golan, D.E.4
Michel, T.5
-
6
-
-
0030770629
-
Caveolin versus calmodulin. Counterbalancing allosteric modulators of endothelial nitric oxide synthase
-
Michel, J.B., Feron, O., Sase, K., Prabhakar, P. & Michel, T. Caveolin versus calmodulin. Counterbalancing allosteric modulators of endothelial nitric oxide synthase. J. Biol. Chem. 272, 25907-25912 (1997).
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 25907-25912
-
-
Michel, J.B.1
Feron, O.2
Sase, K.3
Prabhakar, P.4
Michel, T.5
-
7
-
-
0033542414
-
Regulation of endothelium-derived nitric oxide production by the protein kinase Akt
-
Fulton, D. et al. Regulation of endothelium-derived nitric oxide production by the protein kinase Akt. Nature 399, 597-601 (1999).
-
(1999)
Nature
, vol.399
, pp. 597-601
-
-
Fulton, D.1
-
8
-
-
0009621605
-
Dynamic activation of endothelial nitric oxide synthase by Hsp90
-
Garcia-Cardena, G. et al. Dynamic activation of endothelial nitric oxide synthase by Hsp90. Nature 392, 821-824 (1998).
-
(1998)
Nature
, vol.392
, pp. 821-824
-
-
Garcia-Cardena, G.1
-
9
-
-
0035957984
-
Direct interaction between endothelial nitric-oxide synthase and dynamin-2. Implications for nitric-oxide synthase function
-
Cao, S. et al. Direct interaction between endothelial nitric-oxide synthase and dynamin-2. Implications for nitric-oxide synthase function. J. Biol. Chem. 276, 14249-14256 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 14249-14256
-
-
Cao, S.1
-
10
-
-
0029787241
-
Endothelial nitric oxide synthase targeting to caveolae. Specific interactions with caveolin isoforms in cardiac myocytes and endothelial cells
-
Feron, O. et al. Endothelial nitric oxide synthase targeting to caveolae. Specific interactions with caveolin isoforms in cardiac myocytes and endothelial cells. J. Biol. Chem. 271, 22810-22814 (1996).
-
(1996)
J. Biol. Chem.
, vol.271
, pp. 22810-22814
-
-
Feron, O.1
-
11
-
-
0347379916
-
Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein betagamma subunit signaling to protein kinase B/Akt
-
Liu, S., Premont, R.T., Kontos, C.D., Huang, J. & Rockey, D.C. Endothelin-1 activates endothelial cell nitric-oxide synthase via heterotrimeric G-protein betagamma subunit signaling to protein kinase B/Akt. J. Biol. Chem. 278, 49929-49935 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 49929-49935
-
-
Liu, S.1
Premont, R.T.2
Kontos, C.D.3
Huang, J.4
Rockey, D.C.5
-
12
-
-
0036729484
-
Seven-transmembrane receptors
-
Pierce, K.L., Premont, R.T. & Lefkowitz, R.J. Seven-transmembrane receptors. Nat. Rev. Mol. Cell Biol. 3, 639-650 (2002).
-
(2002)
Nat. Rev. Mol. Cell Biol.
, vol.3
, pp. 639-650
-
-
Pierce, K.L.1
Premont, R.T.2
Lefkowitz, R.J.3
-
13
-
-
0035853775
-
Sphingosine 1-phosphate and activation of endothelial nitric-oxide synthase. Differential regulation of Akt and MAP kinase pathways by EDG and bradykinin receptors in vascular endothelial cells
-
Igarashi, J., Bernier, S.G. & Michel, T. Sphingosine 1-phosphate and activation of endothelial nitric-oxide synthase. Differential regulation of Akt and MAP kinase pathways by EDG and bradykinin receptors in vascular endothelial cells. J. Biol. Chem. 276, 12420-12426 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12420-12426
-
-
Igarashi, J.1
Bernier, S.G.2
Michel, T.3
-
14
-
-
0036087413
-
Adenovirus-mediated gene transfer to nonparenchymal cells in normal and injured liver
-
Yu, Q., Que, L.G. & Rockey, D.C. Adenovirus-mediated gene transfer to nonparenchymal cells in normal and injured liver. Am. J. Physiol. Gastrointest. Liver Physiol. 282, G565-G572 (2002).
-
(2002)
Am. J. Physiol. Gastrointest. Liver Physiol.
, vol.282
-
-
Yu, Q.1
Que, L.G.2
Rockey, D.C.3
-
15
-
-
12144288226
-
Up-regulation of IL-1 receptor through PI3K/Akt is essential for the induction of iNOS gene expression in hepatocytes
-
Teshima, S. et al. Up-regulation of IL-1 receptor through PI3K/Akt is essential for the induction of iNOS gene expression in hepatocytes. J. Hepatol. 40, 616-623 (2004).
-
(2004)
J. Hepatol.
, vol.40
, pp. 616-623
-
-
Teshima, S.1
-
16
-
-
0033607326
-
Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2
-
Carman, C.V. et al. Selective regulation of Galpha(q/11) by an RGS domain in the G protein-coupled receptor kinase, GRK2. J. Biol. Chem. 274, 34483-34492 (1999).
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 34483-34492
-
-
Carman, C.V.1
-
17
-
-
0034691187
-
G protein-coupled receptor kinase-5 regulates thrombin-activated signaling in endothelial cells
-
Tiruppathi, C. et al. G protein-coupled receptor kinase-5 regulates thrombin-activated signaling in endothelial cells. Proc. Natl. Acad. Sci. USA 97, 7440-7445 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 7440-7445
-
-
Tiruppathi, C.1
-
18
-
-
10544242967
-
Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function
-
Jaber, M. et al. Essential role of beta-adrenergic receptor kinase 1 in cardiac development and function. Proc. Natl. Acad. Sci. USA 93, 12974-12979 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 12974-12979
-
-
Jaber, M.1
-
19
-
-
0038322055
-
High density lipoprotein-induced endothelial nitric-oxide synthase activation is mediated by Akt and MAP kinases
-
Mineo, C., Yuhanna, I.S., Quon, M.J. & Shaul, P.W. High density lipoprotein-induced endothelial nitric-oxide synthase activation is mediated by Akt and MAP kinases. J. Biol. Chem. 278, 9142-9149 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 9142-9149
-
-
Mineo, C.1
Yuhanna, I.S.2
Quon, M.J.3
Shaul, P.W.4
-
20
-
-
5344268785
-
Inhibition of Rho-kinase leads to rapid activation of phosphatidyl-inositol 3-kinase/protein kinase Akt and cardiovascular protection
-
Wolfrum, S. et al. Inhibition of Rho-kinase leads to rapid activation of phosphatidyl-inositol 3-kinase/protein kinase Akt and cardiovascular protection. Arterioscler. Thromb. Vasc. Biol. (2004).
-
(2004)
Arterioscler. Thromb. Vasc. Biol.
-
-
Wolfrum, S.1
-
21
-
-
0037383322
-
GSK-3: Tricks of the trade for a multi-tasking kinase
-
Doble, B.W. & Woodgett, J.R. GSK-3: tricks of the trade for a multi-tasking kinase. J. Cell Sci. 116, 1175-1186 (2003).
-
(2003)
J. Cell Sci.
, vol.116
, pp. 1175-1186
-
-
Doble, B.W.1
Woodgett, J.R.2
-
22
-
-
0034845958
-
PKB/Akt: A key mediator of cell proliferation, survival and insulin responses?
-
Lawlor, M.A. & Alessi, D.R. PKB/Akt: a key mediator of cell proliferation, survival and insulin responses? J. Cell Sci. 114, 2903-2910 (2001).
-
(2001)
J. Cell Sci.
, vol.114
, pp. 2903-2910
-
-
Lawlor, M.A.1
Alessi, D.R.2
-
23
-
-
0037104660
-
Akt1 regulates a JNK scaffold during excitotoxic apoptosis
-
Kim, A.H. et al. Akt1 regulates a JNK scaffold during excitotoxic apoptosis. Neuron 35, 697-709 (2002).
-
(2002)
Neuron
, vol.35
, pp. 697-709
-
-
Kim, A.H.1
-
24
-
-
0035850916
-
Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane
-
Maira, S.M. et al. Carboxyl-terminal modulator protein (CTMP), a negative regulator of PKB/Akt and v-Akt at the plasma membrane. Science 294, 374-380 (2001).
-
(2001)
Science
, vol.294
, pp. 374-380
-
-
Maira, S.M.1
-
25
-
-
0031000256
-
G-protein-coupled receptor kinase activity is increased in hypertension
-
Gros, R., Benovic, J.L., Tan, C.M. & Feldman, R.D. G-protein-coupled receptor kinase activity is increased in hypertension. J. Clin. Invest. 99, 2087-2093 (1997).
-
(1997)
J. Clin. Invest.
, vol.99
, pp. 2087-2093
-
-
Gros, R.1
Benovic, J.L.2
Tan, C.M.3
Feldman, R.D.4
-
26
-
-
1942453389
-
Differential functional expression of human myocardial G protein receptor kinases in left ventricular cardiac diseases
-
Dzimiri, N., Muiya, P., Andres, E. & Al-Halees, Z. Differential functional expression of human myocardial G protein receptor kinases in left ventricular cardiac diseases. Eur. J. Pharmacol. 489, 167-177 (2004).
-
(2004)
Eur. J. Pharmacol.
, vol.489
, pp. 167-177
-
-
Dzimiri, N.1
Muiya, P.2
Andres, E.3
Al-Halees, Z.4
-
27
-
-
1842526833
-
Targeted beta-adrenergic receptor kinase (betaARK1) inhibition by gene transfer in failing human hearts
-
Williams, M.L. et al. Targeted beta-adrenergic receptor kinase (betaARK1) inhibition by gene transfer in failing human hearts. Circulation 109, 1590-1593 (2004).
-
(2004)
Circulation
, vol.109
, pp. 1590-1593
-
-
Williams, M.L.1
-
28
-
-
0027299798
-
Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells
-
Hirata, Y. et al. Endothelin receptor subtype B mediates synthesis of nitric oxide by cultured bovine endothelial cells. J. Clin. Invest. 91, 1367-1373 (1993).
-
(1993)
J. Clin. Invest.
, vol.91
, pp. 1367-1373
-
-
Hirata, Y.1
-
29
-
-
0028074215
-
Molecular and functional characterization of the non-isopeptide-selective ETB receptor in endothelial cells. Receptor coupling to nitric oxide synthase
-
Tsukahara, H., Ende, H., Magazine, H.I., Bahou, W.F. & Goligorsky, M.S. Molecular and functional characterization of the non-isopeptide-selective ETB receptor in endothelial cells. Receptor coupling to nitric oxide synthase. J. Biol. Chem. 269, 21778-21785 (1994).
-
(1994)
J. Biol. Chem.
, vol.269
, pp. 21778-21785
-
-
Tsukahara, H.1
Ende, H.2
Magazine, H.I.3
Bahou, W.F.4
Goligorsky, M.S.5
-
30
-
-
0037799206
-
Keeping G proteins at bay: A complex between G protein-coupled receptor kinase 2 and Gbeta-gamma
-
Lodowski, D.T., Pitcher, J.A., Capel, W.D., Lefkowitz, R.J. & Tesmer, J.J. Keeping G proteins at bay: a complex between G protein-coupled receptor kinase 2 and Gbeta-gamma. Science 300, 1256-1262 (2003).
-
(2003)
Science
, vol.300
, pp. 1256-1262
-
-
Lodowski, D.T.1
Pitcher, J.A.2
Capel, W.D.3
Lefkowitz, R.J.4
Tesmer, J.J.5
-
31
-
-
0141629679
-
Mechanisms of regulation of the expression and function of G protein-coupled receptor kinases
-
Penela, P., Ribas, C. & Mayor, F., Jr. Mechanisms of regulation of the expression and function of G protein-coupled receptor kinases. Cell. Signal. 15, 973-981 (2003).
-
(2003)
Cell. Signal.
, vol.15
, pp. 973-981
-
-
Penela, P.1
Ribas, C.2
Mayor Jr., F.3
-
32
-
-
0034595227
-
Analysis of the human G protein-coupled receptor kinase 2 (GRK2) gene promoter: Regulation by signal transduction systems in aortic smooth muscle cells
-
Ramos-Ruiz, R., Penela, P., Penn, R.B. & Mayor, F., Jr. Analysis of the human G protein-coupled receptor kinase 2 (GRK2) gene promoter: regulation by signal transduction systems in aortic smooth muscle cells. Circulation 101, 2083-2089 (2000).
-
(2000)
Circulation
, vol.101
, pp. 2083-2089
-
-
Ramos-Ruiz, R.1
Penela, P.2
Penn, R.B.3
Mayor Jr., F.4
-
33
-
-
0035903669
-
Beta-arrestin- and c-Src-dependent degradation of G-protein-coupled receptor kinase 2
-
Penela, P., Elorza, A., Sarnago, S. & Mayor, F., Jr. Beta-arrestin- and c-Src-dependent degradation of G-protein-coupled receptor kinase 2. EMBO J. 20, 5129-5138 (2001).
-
(2001)
EMBO J.
, vol.20
, pp. 5129-5138
-
-
Penela, P.1
Elorza, A.2
Sarnago, S.3
Mayor Jr., F.4
-
34
-
-
0021987742
-
Uptake of chemically modified low density lipoproteins in vivo is mediated by specific endothelial cells
-
Pitas, R.E., Boyles, J., Mahley, R.W. & Bissell, D.M. Uptake of chemically modified low density lipoproteins in vivo is mediated by specific endothelial cells. J. Cell Biol. 100, 103-117 (1985).
-
(1985)
J. Cell Biol.
, vol.100
, pp. 103-117
-
-
Pitas, R.E.1
Boyles, J.2
Mahley, R.W.3
Bissell, D.M.4
-
35
-
-
0021219239
-
Immunocytochemical detection of desmin in fat-storing cells (Ito cells)
-
Yokoi, Y. et al. Immunocytochemical detection of desmin in fat-storing cells (Ito cells). Hepatology 4, 709-714 (1984).
-
(1984)
Hepatology
, vol.4
, pp. 709-714
-
-
Yokoi, Y.1
-
36
-
-
0021238490
-
Prolonged bile duct obstruction: A new experimental model for cirrhosis in the rat
-
Kountouras, J., Billing, B.H. & Scheuer, P.J. Prolonged bile duct obstruction: a new experimental model for cirrhosis in the rat. Br. J. Exp. Pathol. 65, 305-311 (1984).
-
(1984)
Br. J. Exp. Pathol.
, vol.65
, pp. 305-311
-
-
Kountouras, J.1
Billing, B.H.2
Scheuer, P.J.3
-
37
-
-
0031834338
-
Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt
-
Kontos, C.D. et al. Tyrosine 1101 of Tie2 is the major site of association of p85 and is required for activation of phosphatidylinositol 3-kinase and Akt. Mol. Cell. Biol. 18, 4131-4140 (1998).
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 4131-4140
-
-
Kontos, C.D.1
-
38
-
-
0029823556
-
Monoclonal antibodies reveal receptor specificity among G-protein-coupled receptor kinases
-
Oppermann, M. et al. Monoclonal antibodies reveal receptor specificity among G-protein-coupled receptor kinases. Proc. Natl. Acad. Sci. USA 93, 7649-7654 (1996).
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 7649-7654
-
-
Oppermann, M.1
|