The amyloid precursor protein and its homologues: Structural and functional aspects of native and pathogenic oligomerization

European Journal of Cell Biology

Volumn 91, Issue 4, 2012, Pages 234-239

  Kaden, Daniela ^a   Munter, Lisa Marie ^a   Reif, Bernd ^b,c   Multhaup, Gerd ^a  

^a FREIE UNIVERSITÄT BERLIN   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^c INSTITUTE OF EPIDEMIOLOGY   (Germany)

Author keywords

Amyloid precursor protein (APP); Amyloid beta generation; APLP1; APLP2; Dimer; Heterodimerization; Homodimerization; Structure

Indexed keywords

AMINO ACID; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; AMYLOID PRECURSOR PROTEIN; AMYLOID PRECURSOR PROTEIN 1; AMYLOID PRECURSOR PROTEIN 2; AMYLOID PRECURSOR PROTEIN[18-207]; AMYLOID PRECURSOR PROTEIN[365-570]; COPPER BINDING DOMAIN[127-188]; GROWTH FACTOR LIKE DOMAIN[28-123]; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; AMINO ACID SUBSTITUTION; AMYLOID PLAQUE; COPPER BINDING DOMAIN; CRYSTAL STRUCTURE; CYTOPLASM; DIMERIZATION; GENE MUTATION; GROWTH FACTOR LIKE DOMAIN; HUMAN; INTRACELLULAR SIGNALING; NONHUMAN; OLIGOMERIZATION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN CONFORMATION; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN PROTEIN INTERACTION; PROTEIN STRUCTURE; SHORT SURVEY;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; HUMANS; PROTEIN MULTIMERIZATION; STRUCTURE-ACTIVITY RELATIONSHIP;

EID: 84857355873     PISSN: 01719335     EISSN: 16181298     Source Type: Journal    
DOI: 10.1016/j.ejcb.2011.01.017     Document Type: Short Survey

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