Phenylalanine-rich peptides potently bind ESAT6, a virulence derminant of Mycobacterium tuberculosis, and concurrently affect the pathogen's growth

PLoS ONE

Volumn 4, Issue 11, 2009, Pages

  Kumar, Krishan ^a   Tharad, Megha ^a   Ganapathy, Swetha ^a   Ram, Geeta ^a   Narayan, Azeet ^b   Khan, Jameel Ahmad ^b   Pratap, Rana ^c   Ghosh, Anamika ^a   Samuchiwal, Sachin Kumar ^a   Kumar, Sushil ^a   Bhalla, Kuhulika ^a   Gupta, Deepti ^a   Natarajan, Krishnamurthy ^a   Singh, Yogendra ^b   Ranganathan, Anand ^a  

^a INTERNATIONAL CENTRE FOR GENETIC ENGINEERING AND BIOTECHNOLOGY   (Italy)

^b CSIR INSTITUTE OF GENOMICS AND INTEGRATIVE BIOLOGY   (India)

^c JAWAHARLAL NEHRU UNIVERSITY   (India)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME C OXIDASE; EARLY SECRETORY ANTIGENIC TARGET 6; PEPTIDE; PHENYLALANINE; BACTERIAL ANTIGEN; BACTERIAL PROTEIN; COMPLEMENTARY DNA; ESAT 6 PROTEIN, MYCOBACTERIUM TUBERCULOSIS; ESAT-6 PROTEIN, MYCOBACTERIUM TUBERCULOSIS;

ARTICLE; BACTERIAL CELL WALL; BACTERIAL GROWTH; BACTERIAL SURVIVAL; BACTERIAL VIRULENCE; CONTROLLED STUDY; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; MACROPHAGE; MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; CHEMISTRY; GENE EXPRESSION PROFILING; GENE LIBRARY; GENE VECTOR; LUNG; METABOLISM; MICROBIOLOGY; MOLECULAR CLONING; PATHOGENICITY; PROTEIN BINDING; PROTEIN MICROARRAY; TWO HYBRID SYSTEM;

MYCOBACTERIUM SMEGMATIS; MYCOBACTERIUM TUBERCULOSIS;

ANTIGENS, BACTERIAL; BACTERIAL PROTEINS; CLONING, MOLECULAR; DNA, COMPLEMENTARY; ELECTRON TRANSPORT COMPLEX IV; GENE EXPRESSION PROFILING; GENE LIBRARY; GENETIC VECTORS; HUMANS; LUNG; MYCOBACTERIUM TUBERCULOSIS; PEPTIDES; PHENYLALANINE; PROTEIN ARRAY ANALYSIS; PROTEIN BINDING; TWO-HYBRID SYSTEM TECHNIQUES;

EID: 70450189138     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0007615     Document Type: Article

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