AMPK as target for intervention in childhood and adolescent obesity

Journal of Obesity

Volumn 2011, Issue , 2011, Pages

  Rojas, Joselyn ^a   Arraiz, Nailet ^a   Aguirre, Miguel ^a   Velasco, Manuel ^b   Bermúdez, Valmore ^a  

^a UNIVERSIDAD DEL ZULIA   (Venezuela)

^b UNIVERSIDAD CENTRAL DE VENEZUELA   (Venezuela)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84856580727     PISSN: 20900708     EISSN: 20900716     Source Type: Journal    
DOI: 10.1155/2011/252817     Document Type: Review

References (222)

1. Ulijaszek S. J., Seven models of population obesity. Angiology 2008 59 2 34s 38s 2-s2.0-53049097640
2. Ioannidis I., The road from obesity to type 2 diabetes. Angiology 2008 59 2 39s 43s 2-s2.0-53049084871
3. World Health Organization (WHO), Obesity and overweight. http://www.who.int/mediacentre/factsheets/fs311/en/index.html
4. Ogden C. L., Flegal K. M., Carroll M. D., Johnson C. L., Prevalence and trends in overweight among US children and adolescents, 1999-2000. Journal of the American Medical Association 2002 288 14 1728 1732 2-s2.0-0037048695
5. Sekhobo J. P., jps04@health.state.ny.us Edmunds L. S., Reynolds D. K., Dalenius K., Sharma A., Trends in prevalence of obesity and overweight among children enrolled in the New York State WIC Program, 2002-2007. Public Health Reports 2010 125 2 218 224
6. Berenson G. S., Srinivasan S. R., Bao W., Newman W. P. III, Tracy R. E., Wattigney W. A., Association between multiple cardiovascular risk factors and atherosclerosis in children and young adults. New England Journal of Medicine 1998 338 23 1650 1656 2-s2.0-0032482329 10.1056/NEJM199806043382302 (Pubitemid 28267909)
7. Cole T. J., Bellizzi M. C., Flegal K. M., Dietz W. H., Establishing a standard definition for child overweight and obesity worldwide: international survey. British Medical Journal 2000 320 7244 1240 1243 2-s2.0-0034611996 (Pubitemid 30240471)
8. Kuczmarski R. J., Ogden C. L., Grummer-Strawn L. M., Flegal K. M., Guo S. S., Wei R., Mei Z., Curtin L. R., Roche A. F., Johnson C. L., CDC growth charts: United States. Advance Data 2000 314 1 27 2-s2.0-0034621779
9. Flegal K. M., Wei R., Ogden C., Weight-for-stature compared with body mass index-for-age growth charts for the United States from the Centers for Disease Control and Prevention. American Journal of Clinical Nutrition 2002 75 4 761 766 2-s2.0-0036196955 (Pubitemid 34250691)
10. Alberti K. G. M. M., Zimmet P. Z., Definition, diagnosis and classification of diabetes mellitus and its complications. Part 1: diagnosis and classification of diabetes mellitus. Provisional report of a WHO consultation. Diabetic Medicine 1998 15 7 539 553 2-s2.0-0031851293 (Pubitemid 28319935)
11. Balkau B., Charles M. A., Comment on the provisional report from the WHO consultation. Diabetic Medicine 1999 16 5 442 443 10.1046/j.1464-5491.1999. 00059.x
12. Third Report of the National Cholesterol Education Program (NCEP) expert panel on detection, evaluation, and treatment of high blood cholesterol in adults (adult treatment panel III) final report. Circulation 2002 106 25 3143 3421 2-s2.0-0037126526
13. Alberti K. G. M. M., Zimmet P., Shaw J., Metabolic syndrome-a new world-wide definition. A consensus statement from the International Diabetes Federation. Diabetic Medicine 2006 23 5 469 480 2-s2.0-33645978121 10.1111/j.1464-5491.2006.01858.x
14. Grundy S. M., Cleeman J. I., Daniels S. R., Donato K. A., Eckel R. H., Franklin B. A., Gordon D. J., Krauss R. M., Savage P. J., Smith S. C. Jr., Spertus J. A., Costa F., Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute scientific statement. Circulation 2005 112 17 2735 2752 2-s2.0-27444443876 10.1161/CIRCULATIONAHA.105.169404 (Pubitemid 41532612)
15. Robert A., Eckel R. H., Grundy S. M., Zimmet P. Z., Cleeman J. I., Donato K. A., Fruchart J.-C., James W. P. T., Loria C. M., Smith S. C., Harmonizing the metabolic syndrome: a joint interim statement of the international diabetes federation task force on epidemiology and prevention; National heart, lung, and blood institute; American heart association; World heart federation; International atherosclerosis society; And international association for the study of obesity. Circulation 2009 120 16 1640 1645 2-s2.0-70350245011 10.1161/CIRCULATIONAHA.109.192644
16. Goodman E., Daniels S. R., Meigs J. B., Dolan L. M., Instability in the diagnosis of metabolic syndrome in adolescents. Circulation 2007 115 17 2316 2322 2-s2.0-34247571404 10.1161/CIRCULATIONAHA.106.669994 (Pubitemid 46691226)
17. Sun S. S., Liang R., Huang T. T.-K., Daniels S. R., Arslanian S., Liu K., Grave G. D., Siervogel R. M., Childhood obesity predicts adult metabolic syndrome: the Fels Longitudinal Study. Journal of Pediatrics 2008 152 2 191 200 2-s2.0-38149101820 10.1016/j.jpeds.2007.07.055
18. Beg Z. H., Allmann D. W., Gibson D. M., Modulation of 3 hydroxy 3 methylglutaryl coenzyme A reductase activity with cAMP and with protein fractions of rat liver cytosol. Biochemical and Biophysical Research Communications 1973 54 4 1362 1369 2-s2.0-0015864346
19. Carlson C. A., Kim K. H., Regulation of hepatic acetyl coenzyme A carboxylase by phosphorylation and dephosphorylation. Journal of Biological Chemistry 1973 248 1 378 380 2-s2.0-0015918822
20. Hardie D. G., Scott J. W., Pan D. A., Hudson E. R., Management of cellular energy by the AMP-activated protein kinase system. FEBS Letters 2003 546 1 113 120 2-s2.0-0038199737 10.1016/S0014-5793(03)00560-X (Pubitemid 36782291)
21. Osler M. E., Zierath J. R., Minireview: adenosine 5′-monophosphate- activated protein kinase regulation of fatty acid oxidation in skeletal muscle. Endocrinology 2008 149 3 935 941 2-s2.0-40849092782 10.1210/en.2007-1441 (Pubitemid 351397910)
22. Schwartz M. W., Woods S. C., Porte D. Jr., Seeley R. J., Baskin D. G., Central nervous system control of food intake. Nature 2000 404 6778 661 671 2-s2.0-0034611732 (Pubitemid 30205071)
23. Druce M. R., Small C. J., Bloom S. R., Minireview: gut peptides regulating satiety. Endocrinology 2004 145 6 2660 2665 2-s2.0-2542479964 10.1210/en.2004-0089 (Pubitemid 38686212)
24. Roth C. L., Enriori P. J., Harz K., Woelfle J., Cowley M. A., Reinehr T., Peptide YY is a regulator of energy homeostasis in obese children before and after weight loss. Journal of Clinical Endocrinology and Metabolism 2005 90 12 6386 6391 2-s2.0-28744442164 10.1210/jc.2005-1357 (Pubitemid 41759289)
25. Furnes M. W., Zhao C. M., Stenstrom B., Arum C. J., Tommeras K., Kulseng B., Chen D., Feeding behavior and body weight development: lessons from rats subjected to gastric bypass surgery or high-fat diet. Journal of Physiology and Pharmacology 2009 60 7 25 31
26. Granata R., Settanni F., Gallo D., Trovato L., Biancone L., Cantaluppi V., Nano R., Annunziata M., Campiglia P., Arnoletti E., Ghé C., Volante M., Papotti M., Muccioli G., Ghigo E., Obestatin promotes survival of pancreatic β -cells and human islets and induces expression of genes involved in the regulation of β -cell mass and function. Diabetes 2008 57 4 967 979 2-s2.0-42449124783 10.2337/db07-1104
27. Cordido F., Isidro M. L., Nemiña R., Sangiao-Alvarellos S., Ghrelin and growth hormone secretagogues, physiological and pharmacological aspect. Current Drug Discovery Technologies 2009 6 1 34 42 2-s2.0-62149141741 10.2174/157016309787581048
28. Gil-Campos M., Aguilera C. M., Cañete R., Gil A., Ghrelin: a hormone regulating food intake and energy homeostasis. British Journal of Nutrition 2006 96 2 201 226 2-s2.0-33750115577 10.1079/BJN20061787 (Pubitemid 46476321)
29. James R. J. A., Drewett R. F., Cheetham T. D., Low cord ghrelin levels in term infants are associated with slow weight gain over the first 3 months of life. Journal of Clinical Endocrinology and Metabolism 2004 89 8 3847 3850 2-s2.0-4043062050 10.1210/jc.2003-032167 (Pubitemid 39071483)
30. Darendeliler F., Bas F., Bundak R., Coban A., Disci R., Sancakli O., Gokcay G., Ince Z., Can G., Elevated ghrelin levels in preterm born children during prepubertal ages and relationship with catch-up growth. European Journal of Endocrinology 2008 159 5 555 560 2-s2.0-56749181008 10.1530/EJE-08-0357
31. Darendeliler F., Poyrazoglu S., Bas F., Sancakli O., Gokcay G., Ghrelin levels are decreased in non-obese prepubertal children born large for gestational age. European Journal of Endocrinology 2009 160 6 951 956 2-s2.0-66149127240 10.1530/EJE-08-0924
32. Maffeis C., Bonadonna R. C., Consolaro A., Vettor R., Banzato C., Silvagni D., Bogoni G., Pellegrino M., Tatò L., Ghrelin, insulin sensitivity and postprandial glucose disposal in overweight and obese children. European Journal of Endocrinology 2006 154 1 61 68 2-s2.0-32844460763 10.1530/eje.1.02055 (Pubitemid 43250737)
33. Bellone S., Castellino N., Broglio F., Rapa A., Vivenza D., Radetti G., Bellone J., Gottero C., Ghigo E., Bona G., Ghrelin secretion in childhood is refractory to the inhibitory effect of feeding. Journal of Clinical Endocrinology and Metabolism 2004 89 4 1662 1665 2-s2.0-11144356392 10.1210/jc.2003-031207 (Pubitemid 38507918)
34. Murdolo G., Lucidi P., Di Loreto C., Parlanti N., De Cicco A., Fatone C., Fanelli C. G., Bolli G. B., Santeusanio F., De Feo P., Insulin is required for prandial ghrelin suppression in humans. Diabetes 2003 52 12 2923 2927 2-s2.0-10744227324 10.2337/diabetes.52.12.2923 (Pubitemid 37466861)
35. Bacha F., Arslanian S. A., Ghrelin suppression in overweight children: a manifestation of insulin resistance? Journal of Clinical Endocrinology and Metabolism 2005 90 5 2725 2730 2-s2.0-18844363147 10.1210/jc.2004-1582 (Pubitemid 40686316)
36. Maes H. H. M., Neale M. C., Eaves L. J., Genetic and environmental factors in relative body weight and human adiposity. Behavior Genetics 1997 27 4 325 351 2-s2.0-0030843960 10.1023/A:1025635913927 (Pubitemid 27415169)
37. Montague C. T., Farooqi I. S., Whitehead J. P., Soos M. A., Rau H., Wareham N. J., Sewter C. P., Digby J. E., Mohammed S. N., Hurst J. A., Cheetham C. H., Earley A. R., Barnett A. H., Prins J. B., O'Rahilly S., Congenital leptin deficiency is associated with severe early-onset obesity in humans. Nature 1997 387 6636 903 908 2-s2.0-0030878110 10.1038/43185 (Pubitemid 27289591)
38. Sadaf Farooqi I., Matarese G., Lord G. M., Keogh J. M., Lawrence E., Agwu C., Sanna V., Jebb S. A., Perna F., Fontana S., Lechler R. I., Depaoli A. M., O'Rahilly S., Beneficial effects of leptin on obesity, T cell hyporesponsiveness, and neuroendocrine/metabolic dysfunction of human congenital leptin deficiency. Journal of Clinical Investigation 2002 110 8 1093 1103 2-s2.0-0036800760 10.1172/JCI200215693 (Pubitemid 35215890)
39. Strobel A., Issad T., Camoin L., Ozata M., Strosberg A. D., A leptin missense mutation associated with hypogonadism and morbid obesity. Nature Genetics 1998 18 3 213 215 2-s2.0-0032014836
40. Gibson W. T., wtgibson@cmmt.ubc.ca Farooqi I. S., Moreau M., DePaoli A. M., Lawrence E., O'Rahilly S., Trussell R. A., Congenital leptin deficiency due to homozygosity for the Δ 133G mutation: report of another case and evaluation of response to four years of leptin therapy. Journal of Clinical Endocrinology and Metabolism 2004 89 10 4821 4826 10.1210/jc.2004-0376 (Pubitemid 39391413)
41. Pérusse L., Rankinen T., Zuberi A., Chagnon Y. C., Weisnagel S. J., Argyropoulos G., Walts B., Snyder E. E., Bouchard C., The human obesity gene map: the 2004 update. Obesity Research 2005 13 3 381 490 2-s2.0-20544471519
42. Menzaghi C., Ercolino T., Paola R. D., Berg A. H., Warram J. H., Scherer P. E., Trischitta V., Doria A., A haplotype at the adiponectin locus is associated with obesity and other features of the insulin resistance syndrome. Diabetes 2002 51 7 2306 2312 2-s2.0-0036307162 (Pubitemid 34729040)
43. Filippi E., Sentinelli F., Trischitta V., Romeo S., Arca M., Leonetti F., Di Mario U., Baroni M. G., Association of the human adiponectin gene and insulin resistance. European Journal of Human Genetics 2004 12 3 199 205 2-s2.0-3342997341 10.1038/sj.ejhg.5201120 (Pubitemid 38499978)
44. Ukkola O., Rankinen T., Weisnagel S.J., Interactions among the α 2- and β 2 adrenoreceptor genes and regional fat distribution in humans: association and linkage studies. Obesity Research 1995 3 249 255 2-s2.0-0032014836
45. Garenc C., Pérusse L., Chagnon Y. C., Rankinen T., Gagnon J., Borecki I. B., Leon A. S., Skinner J. S., Wilmore J. H., Rao D. C., Bouchard C., The α 2-adrenergic receptor gene and body fat content and distribution: the HERITAGE family study. Molecular Medicine 2002 8 2 88 94 2-s2.0-0035982901 (Pubitemid 35013576)
46. Mammès O., Betoulle D., Aubert R., Giraud V., Tuzet S., Petiet A., Colas-Linhart N., Fumeron F., Novel polymorphisms in the 5' region of the LEP gene: association with leptin levels and response to low-calorie diet in human obesity. Diabetes 1998 47 3 487 489 2-s2.0-0031892748 10.2337/diabetes.47.3.487 (Pubitemid 28104215)
47. Mammès O., Betoulle D., Aubert R., Herbeth B., Siest G., Fumeron F., Association of the G-2548A polymorphism in the 5′ region of the LEP gene with overweight. Annals of Human Genetics 2000 64 5 391 394 2-s2.0-0034527931 10.1017/S0003480000008277 (Pubitemid 32055730)
48. Li W.-D., Reed D. R., Lee J. H., Xu W., Kilker R. L., Sodam B. R., Price R. A., Sequence variants in the 5' flanking region of the leptin gene are associated with obesity in women. Annals of Human Genetics 1999 63 3 227 234 2-s2.0-0032871802 10.1017/S0003480099007496 (Pubitemid 29471966)
49. Roussel R., Reis A. F., Dubois-Laforgue D., Bellanné-Chantelot C., Timsit J., Velho G., The N363S polymorphism in the glucocorticoid receptor gene is associated with overweight in subjects with type 2 diabetes mellitus. Clinical Endocrinology 2003 59 2 237 241 2-s2.0-0041664880 10.1046/j.1365-2265. 2003.01831.x (Pubitemid 36918661)
50. Ek J., Urhammer S. A., Sørensen T. I. A., Andersen T., Auwerx J., Pedersen O., Homozygosity of the Pro12Ala variant of the peroxisome proliferation- activated receptor- γ 2 (PPAR- γ 2): divergent modulating effects on body mass index in obese and lean Caucasian men. Diabetologia 1999 42 7 892 895 2-s2.0-0032781890 10.1007/s001250051243 (Pubitemid 29325082)
51. Öhman M., Oksanen L., Kaprio J., Koskenvuo M., Mustajoki P., Rissanen A., Salmi J., Kontula K., Peltonen L., Genome-wide scan of obesity in finnish sibpairs reveals linkage to chromosome Xq24. Journal of Clinical Endocrinology and Metabolism 2000 85 9 3183 3190 2-s2.0-0033694150
52. Barker D. J. P., Fetal origins of coronary heart disease. British Medical Journal 1995 311 6998 171 174 2-s2.0-0029050563
53. Fleming T. P., Kwong W. Y., Porter R., Ursell E., Fesenko I., Wilkins A., Miller D. J., Watkins A. J., Eckert J. J., The embryo and its future. Biology of Reproduction 2004 71 4 1046 1054 2-s2.0-4544319546 10.1095/biolreprod.104. 030957 (Pubitemid 39249786)
54. Vickers M. H., Reddy S., Ikenasio B. A., Breier B. H., Dysregulation of the adipoinsular axis-a mechanism for the pathogenesis of hyperleptinemia and adipogenic diabetes induced by fetal programming. Journal of Endocrinology 2001 170 2 323 332 2-s2.0-0034887287 10.1677/joe.0.1700323 (Pubitemid 32771434)
55. Roza S. J., Steegers E. A. P., Verburg B. O., Jaddoe V. W. V., Moll H. A., Hofman A., Verhulst F. C., Tiemeier H., What is spared by fetal brain-sparing? Fetal circulatory redistribution and behavioral problems in the general population. American Journal of Epidemiology 2008 168 10 1145 1152 2-s2.0-56149087551 10.1093/aje/kwn233
56. Rozance P. J., Limesand S. W., Barry J. S., Brown L. D., Hay W. W. Jr., Glucose replacement to euglycemia causes hypoxia, acidosis, and decreased insulin secretion in fetal sheep with intrauterine growth restriction. Pediatric Research 2009 65 1 72 78 2-s2.0-58149391765 10.1203/PDR.0b013e318189358c
57. Jaquet D., Leger J., Levy-Marchal C., Oury J. F., Czernichow P., Ontogeny of leptin in human fetuses and newborns: effect of intrauterine growth retardation on serum leptin concentrations. Journal of Clinical Endocrinology and Metabolism 1998 83 4 1243 1246 2-s2.0-0031790849 10.1210/jc.83.4.1243 (Pubitemid 28496401)
58. McMillen I. C., Muhlhausler B. S., Duffield J. A., Yuen B. S. J., Prenatal programming of postnatal obesity: fetal nutrition and the regulation of leptin synthesis and secretion before birth. Proceedings of the Nutrition Society 2004 63 3 405 412 2-s2.0-4344650450 10.1079/PNS2004370 (Pubitemid 39145499)
59. Wallace J. M., Aitken R. P., Milne J. S., Hay W. W. Jr., Nutritionally mediated placental growth restriction in the growing adolescent: consequences for the fetus. Biology of Reproduction 2004 71 4 1055 1062 2-s2.0-4544331081 10.1095/biolreprod.104.030965 (Pubitemid 39249787)
60. Jaquet D., Leger J., Levy-Marchal C., Oury J. F., Czernichow P., Ontogeny of leptin in human fetuses and newborns: effect of intrauterine growth retardation on serum leptin concentrations. Journal of Clinical Endocrinology and Metabolism 1998 83 4 1243 1246 2-s2.0-0031790849 10.1210/jc.83.4.1243 (Pubitemid 28496401)
61. Vickers M. H., Breier B. H., Cutfield W. S., Hofman P. L., Gluckman P. D., Fetal origins of hyperphagia, obesity, and hypertension and postnatal amplification by hypercaloric nutrition. American Journal of Physiology 2000 279 1 E83 E87 2-s2.0-0033854908 (Pubitemid 30609948)
62. Ekert J. E., Gatford K. L., Luxford B. G., Campbell R. G., Owens P. C., Leptin expression in offspring is programmed by nutrition in pregnancy. Journal of Endocrinology 2000 165 3 R1 R6 2-s2.0-0034099728 (Pubitemid 30407702)
63. Thomas L., Wallace J. M., Aitken R. P., Mercer J. G., Trayhurn P., Hoggard N., Circulating leptin during ovine pregnancy in relation to maternal nutrition, body composition and pregnancy outcome. Journal of Endocrinology 2001 169 3 465 476 2-s2.0-0034965673 10.1677/joe.0.1690465 (Pubitemid 32536980)
64. Ehrhardt R. A., Bell A. W., Boisclair Y. R., Spatial and developmental regulation of leptin in fetal sheep. American Journal of Physiology 2002 282 6 R1628 R1635 2-s2.0-0036087068 (Pubitemid 34664487)
65. Mühlhäusler B. S., Roberts C. T., McFarlane J. R., Kauter K. G., McMillen I. C., Fetal leptin is a signal of fat mass independent of maternal nutrition in ewes fed at or above maintenance energy requirements. Biology of Reproduction 2002 67 2 493 499 2-s2.0-0035992841 (Pubitemid 34803935)
66. Mühlhäusler B. S., Roberts C. T., Yuen B. S. J., Marrocco E., Budge H., Symonds M. E., McFarlane J. R., Kauter K. G., Stagg P., Pearse J. K., McMillen I. C., Determinants of fetal leptin synthesis, fat mass, and circulating leptin concentrations in Well-Nourished ewes in late pregnancy. Endocrinology 2003 144 11 4947 4954 2-s2.0-9144262628 10.1210/en.2003-0555 (Pubitemid 37378409)
67. Gardner D. S., Tingey K., Van Bon B. W. M., Ozanne S. E., Wilson V., Dandrea J., Keisler D. H., Stephenson T., Symonds M. E., Programming of glucose-insulin metabolism in adult sheep after maternal undernutrition. American Journal of Physiology 2005 289 4 R947 R954 2-s2.0-25844467816 10.1152/ajpregu.00120.2005 (Pubitemid 41397040)
68. Ford S. P., Hess B. W., Schwope M. M., Nijland M. J., Gilbert J. S., Vonnahme K. A., Means W. J., Han H., Nathanielsz P. W., Maternal undernutrition during early to mid-gestation in the ewe results in altered growth, adiposity, and glucose tolerance in male offspring. Journal of Animal Science 2007 85 5 1285 1294 2-s2.0-34247884283 10.2527/jas.2005-624 (Pubitemid 46693428)
69. Petersen H. V., Peshavaria M., Pedersen A. A., Philippe J., Stein R., Madsen O. D., Serup P., Glucose stimulates the activation domain potential of the PDX-1 homeodomain transcription factor. FEBS Letters 1998 431 3 362 366 2-s2.0-0032563330 10.1016/S0014-5793(98)00776-5 (Pubitemid 28352390)
70. Desai M., G. H., Ferelli M., Kallichanda N., Lane R. H., Programmed upregulation of adipogenic transcription factors in intrauterine growth-restricted offspring. Reproductive Sciences 2008 15 8 785 796 2-s2.0-54349128127 10.1177/1933719108318597
71. Thompson R. F., Fazzari M. J., Niu H., Barzilai N., Simmons R. A., rsimmons@mail.med.upenn.edu Greally J. M., john.greally@einstein.yu.edu Experimental intrauterine growth restriction induces alterations in DNA methylation and gene expression in pancreatic islets of rats. Journal of Biological Chemistry 2010 285 20 15111 15118 10.1074/jbc.M109.095133
72. Limesand S. W., Jensen J., Hutton J. C., Hay W. W. Jr., Diminished β -cell replication contributes to reduced β -cell mass in fetal sheep with intrauterine growth restriction. American Journal of Physiology 2005 288 5 R1297 R1305 2-s2.0-17844371675 10.1152/ajpregu.00494.2004 (Pubitemid 40593714)
73. Thorn S. R., Regnault T. R. H., Brown L. D., Rozance P. J., Keng J., Roper M., Wilkening R. B., Hay W. W. Jr., Friedman J. E., Intrauterine growth restriction increases fetal hepatic gluconeogenic capacity and reduces messenger ribonucleic acid translation initiation and nutrient sensing in fetal liver and skeletal muscle. Endocrinology 2009 150 7 3021 3030 2-s2.0-67649658047 10.1210/en.2008-1789
74. Delahaye F., Breton C., Risold P.-Y., Enache M., Dutriez-Casteloot I., Laborie C., Lesage J., Vieau D., Maternal perinatal undernutrition drastically reduces postnatal leptin surge and affects the development of arcuate nucleus proopiomelanocortin neurons in neonatal male rat pups. Endocrinology 2008 149 2 470 475 2-s2.0-38549134585 10.1210/en.2007-1263 (Pubitemid 351159317)
75. Breton C., Lukaszewski M.-A., Risold P.-Y., Enache M., Guillemot J., Rivière G., Delahaye F., Lesage J., Dutriez-Casteloot I., Laborie C., Vieau D., Maternal prenatal undernutrition alters the response of POMC neurons to energy status variation in adult male rat offspring. American Journal of Physiology 2009 296 3 E462 E472 2-s2.0-64749111414 10.1152/ajpendo.90740.2008
76. Warnes K. E., Morris M. J., Symonds M. E., Phillips I. D., Clarke I. J., Owens J. A., McMillen I. C., Effects of increasing gestation, cortisol and maternal undernutrition on hypothalamic Neuropeptide Y expression in the sheep fetus. Journal of Neuroendocrinology 2008 10 1 51 57
77. Fletcher A. J. W., Edwards C. M. B., Gardner D. S., Fowden A. L., Giussani D. A., Neuropeptide Y in the sheep fetus: effects of acute hypoxemia and dexamethasone during late gestation. Endocrinology 2000 141 11 3976 3982 2-s2.0-0033712105
78. Huizinga C. T., Oudejans C. B. M., Delemarre-van de Waal H. A., Persistent changes in somatostatin and neuropeptide Y mRNA levels but not in growth hormone-releasing hormone mRNA levels in adult rats after intrauterine growth retardation. Journal of Endocrinology 2001 168 2 273 281 2-s2.0-0035114465 10.1677/joe.0.1680273 (Pubitemid 32181605)
79. Bouret S. G., sbouret@chla.usc.edu Role of early hormonal and nutritional experiences in shaping feeding behavior and hypothalamic development. Journal of Nutrition 2010 140 3 653 657 10.3945/jn.109.112433
80. Coupé B., Amarger V., Grit I., Benani A., Parnet P., patricia.parnet@univ-nantes.fr Nutritional programming affects hypothalamic organization and early response to leptin. Endocrinology 2010 151 2 702 713 10.1210/en.2009-0893
81. Freinkel N., Of pregnancy and progeny. Diabetes 1980 29 12 1023 1035 2-s2.0-0019241940 (Pubitemid 11017928)
82. Pettitt D. J., Knowler W. C., Baird H. R., Bennett P. H., Gestational diabetes: infant and maternal complications of pregnancy in relation to third-trimester glucose tolerance in the Pima Indians. Diabetes Care 1980 3 3 458 464 2-s2.0-0019308550 (Pubitemid 10000695)
83. Franks P. W., Looker H. C., Kobes S., Touger L., Tataranni P. A., Hanson R. L., Knowler W. C., Gestational glucose tolerance and risk of type 2 diabetes in young Pima Indian offspring. Diabetes 2006 55 2 460 465 2-s2.0-33644781772 10.2337/diabetes.55.02.06.db05-0823 (Pubitemid 43343276)
84. Touger L., Looker H. C., Krakoff J., Lindsay R. S., Cook V., Knowler W. C., Early growth in offspring of diabetic mothers. Diabetes Care 2005 28 3 585 589 2-s2.0-14644390903 10.2337/diacare.28.3.585 (Pubitemid 40315317)
85. McCance D. R., Pettitt D. J., Hanson R. L., Jacobsson L. T. H., Knowler W. C., Bennett P. H., Birth weight and non-insulin dependent diabetes: thrifty genotype, thrifty phenotype, or surviving small baby genotype? British Medical Journal 1994 308 6934 942 945 2-s2.0-0028175563
86. Westgate J. A., Lindsay R. S., Beattie J., Pattison N. S., Gamble G., Mildenhall L. F. J., Breier B. H., Johnstone F. D., Hyperinsulinemia in cord blood in mothers with type 2 diabetes and gestational diabetes mellitus in New Zealand. Diabetes Care 2006 29 6 1345 1350 2-s2.0-33746431414 10.2337/dc05-1677 (Pubitemid 44125933)
87. Rao A. K., Daniels K., El-Sayed Y. Y., Moshesh M. K., Caughey A. B., Perinatal outcomes among Asian American and Pacific Islander women. American Journal of Obstetrics and Gynecology 2006 195 3 834 838 2-s2.0-33747878308 10.1016/j.ajog.2006.06.079 (Pubitemid 44292145)
88. Simmons D., Breier B. H., Fetal overnutrition in polynesian pregnancies and in gestational diabetes may lead to dysregulation of the adipoinsular axis in offspring. Diabetes Care 2002 25 9 1539 1544 2-s2.0-0036728864 10.2337/diacare.25.9.1539 (Pubitemid 41071108)
89. McMillen I. C., Muhlhausler B. S., Duffield J. A., Yuen B. S. J., Prenatal programming of postnatal obesity: fetal nutrition and the regulation of leptin synthesis and secretion before birth. Proceedings of the Nutrition Society 2004 63 3 405 412 2-s2.0-4344650450 10.1079/PNS2004370 (Pubitemid 39145499)
90. Zhu M. J., Han B., Tong J., Ma C., Kimzey J. M., Underwood K. R., Xiao Y., Hess B. W., Ford S. P., Nathanielsz P. W., Du M., AMP-activated protein kinase signalling pathways are down regulated and skeletal muscle development impaired in fetuses of obese, over-nourished sheep. Journal of Physiology 2008 586 10 2651 2664 2-s2.0-43749110487 10.1113/jphysiol.2007.149633 (Pubitemid 351689818)
91. Philp L. K., Muhlhausler B. S., Janovska A., Wittert G. A., Duffield J. A., McMillen I. C., Maternal overnutrition suppresses the phosphorylation of 5′ -AMP-activated protein kinase in liver, but not skeletal muscle, in the fetal and neonatal sheep. American Journal of Physiology 2008 295 6 R1982 R1990 2-s2.0-57749113097 10.1152/ajpregu.90492.2008
92. Du M., mindu@uwyo.edu Yan X., Tong J. F., Zhao J., Zhu M. J., Maternal obesity, inflammation, and fetal skeletal muscle development. Biology of Reproduction 2010 82 1 4 12 10.1095/biolreprod.109.077099
93. Vickers M. H., Gluckman P. D., Coveny A. H., Hofman P. L., Cutfield W. S., Gertler A., Breier B. H., Harris M., Neonatal leptin treatment reverses developmental programming. Endocrinology 2005 146 10 4211 4216 2-s2.0-24944471310 10.1210/en.2005-0581 (Pubitemid 41324016)
94. Vickers M. H., Gluckman P. D., Coveny A. H., Hofman P. L., Cutfield W. S., Gertler A., Breier B. H., Harris M., The effect of neonatal leptin treatment on postnatal weight gain in male rats is dependent on maternal nutritional status during pregnancy. Endocrinology 2008 149 4 1906 1913 2-s2.0-41549115092 10.1210/en.2007-0981 (Pubitemid 351468318)
95. Wyrwoll C. S., Mark P. J., Mori T. A., Puddey I. B., Waddell B. J., Prevention of programmed hyperleptinemia and hypertension by postnatal dietary ω -3 fatty acids. Endocrinology 2006 147 1 599 606 2-s2.0-29344457412 10.1210/en.2005-0748 (Pubitemid 43004314)
96. Zambrano E., zamgon@servidor.unam.mx Martínez-Samayoa P. M., Rodríguez-González G. L., Nathanielsz P. W., Dietary intervention prior to pregnancy reverses metabolic programming in male offspring of obese rats. Journal of Physiology 2010 588 10 1791 1799 10.1113/jphysiol.2010.190033
97. Resnik R., Intrauterine growth restriction. Obstetrics and Gynecology 2002 99 3 490 496 2-s2.0-0036186353 10.1016/S0029-7844(01)01780-X (Pubitemid 34188412)
98. Kramer M. S., The epidemiology of adverse pregnancy outcomes: an overview. Journal of Nutrition 2003 133 5 2-s2.0-0038222513
99. Galtier-Dereure F., Boegner C., Bringer J., Obesity and pregnancy: complications and cost. American Journal of Clinical Nutrition 2000 71 5 1242S 1248S 2-s2.0-0034017070 (Pubitemid 30230524)
100. Ordovas J. M., Mooser V., Nutrigenomics and nutrigenetics. Current Opinion in Lipidology 2004 15 2 101 108 2-s2.0-1842609791 10.1097/00041433- 200404000-00002 (Pubitemid 38453397)
101. Freedman M. R., King J., Kennedy E., Popular diets: a scientific review. Obesity Research 2001 9 supplement 1 1S 40S 2-s2.0-3042583361
102. Raben A., Macdonald I., Astrup A., Replacement of dietary fat by sucrose or starch: effects on 14d ad libitum energy intake, energy expenditure and body weight in formerly obese and never-obese subjects. International Journal of Obesity 1997 21 10 846 859 (Pubitemid 27427473)
103. Blum C. B., Levy R. I., Role of dietary intervention in the primary prevention of coronary heart disease. Individuals with high-normal or elevated serum cholesterol levels should be placed on cholesterol-lowering diets. Cardiology 1987 74 1 2 21 (Pubitemid 17219724)
104. Atkins R., Dr Atkins' New Diet Revolution 2002 New York, NY, USA Harper Collins
105. Porrini M., Santangelo A., Crovetti R., Riso P., Testolin G., Blundell J. E., Weight, protein, fat, and timing of preloads affect food intake. Physiology and Behavior 1997 62 3 563 570 2-s2.0-0030920420 10.1016/S0031-9384(97)00162-5 (Pubitemid 27376293)
106. Sharman M. J., Gómez A. L., Kraemer W. J., Volek J. S., Very low carbohydrate and low-fat diets affect fasting lipids and postprandial lipemia differently in overweight men. Journal of Nutrition 2004 134 4 880 885 2-s2.0-1842478313 (Pubitemid 38456258)
107. Bravata D. M., Sanders L., Huang J., Efficacy and safety of low-carbohydrate diets. Journal of the American Medical Association 2003 289 14 1837 1850 2-s2.0-0038413844 10.1001/jama.289.14.1837 (Pubitemid 37430255)
108. Astrup P. A., Meinert Larsen D. T., Harper A., Atkins and other low-carbohydrate diets: hoax or an effective tool for weight loss? The Lancet 2004 364 9437 897 899 2-s2.0-4544255408 10.1016/S0140-6736(04)16986-9 (Pubitemid 39221068)
109. Kushner R. F., Doerfler B., Low-carbohydrate, high-protein diets revisited. Current Opinion in Gastroenterology 2008 24 2 198 203 2-s2.0-40049096482 10.1097/MOG.0b013e3282f43a87 (Pubitemid 351322787)
110. Brehm B. J., D'Alessio D. A., Benefits of high-protein weight loss diets: enough evidence for practice? Current Opinion in Endocrinology, Diabetes and Obesity 2008 15 5 416 421 2-s2.0-53549088576 10.1097/MED.0b013e328308dc13
111. Malik V. S., Hu F. B., Popular weight-loss diets: from evidence to practice. Nature Review Cardiology 2007 4 1 34 41 (Pubitemid 44971070)
112. Hardie D. G., Hawley S. A., Scott J. W., AMP-activated protein kinase-development of the energy sensor concept. Journal of Physiology 2006 574 1 7 15 2-s2.0-33745225026 10.1113/jphysiol.2006.108944 (Pubitemid 43905792)
113. Tschöp M. H., Hui D. Y., Horvath T. L., Diet-induced leptin resistance: The heart of the matter. Endocrinology 2007 148 3 921 923 2-s2.0-33847042351 10.1210/en.2006-1708
114. McGarry J. D., denis.mcgarry@utsouthwestern.edu Dysregulation of fatty acid metabolism in the etiology of type 2 diabetes. Diabetes 2002 51 1 7 18
115. Liu Y., Wan Q., Guan Q., Gao L., Zhao J., High-fat diet feeding impairs both the expression and activity of AMPKa in rats' skeletal muscle. Biochemical and Biophysical Research Communications 2006 339 2 701 707 2-s2.0-28444497837 10.1016/j.bbrc.2005.11.068 (Pubitemid 41739724)
116. Daval M., Foufelle F., Ferré P., pferre@bhdc.jussieu.fr Functions of AMP-activated protein kinase in adipose tissue. Journal of Physiology 2006 574 1 55 62 10.1113/jphysiol.2006.111484 (Pubitemid 43905796)
117. Martin T. L., Alquier T., Asakura K., Furukawa N., Preitner F., Kahn B. B., Diet-induced obesity alters AMP kinase activity in hypothalamus and skeletal muscle. Journal of Biological Chemistry 2006 281 28 18933 18941 2-s2.0-33745224043 10.1074/jbc.M512831200 (Pubitemid 44035396)
118. Taylor E. B., Ellingson W. J., Lamb J. D., Chesser D. G., Winder W. W., Long-chain acyl-CoA esters inhibit phosphorylation of AMP-activated protein kinase at threonine-172 by LKB1/STRAD/MO25. American Journal of Physiology 2005 288 6 E1055 E1061 2-s2.0-19444364151 10.1152/ajpendo.00516.2004 (Pubitemid 40726790)
119. Ruzickova J., Rossmeisl M., Prazak T., Flachs P., Sponarova J., Vecka M., Tvrzicka E., Bryhn M., Kopecky J., Omega-3 PUFA of marine origin limit diet-induced obesity in mice by reducing cellularity of adipose tissue. Lipids 2004 39 12 1177 1185 2-s2.0-12544260664 10.1007/s11745-004-1345-9 L9552
120. Ruxton C. H. S., Reed S. C., Simpson M. J. A., Millington K. J., The health benefits of omega-3 polyunsaturated fatty acids: a review of the evidence. Journal of Human Nutrition and Dietetics 2004 17 5 449 459 2-s2.0-4744369936 10.1111/j.1365-277X.2004.00552.x (Pubitemid 39307100)
121. Nestel P. J., Connor W. E., Reardon M. F., Suppression by diets rich in fish oil of very low density lipoprotein production in man. Journal of Clinical Investigation 1984 74 1 82 89 2-s2.0-0021278243 (Pubitemid 14086047)
122. Kus V., Prazak T., Brauner P., Hensler M., Kuda O., Flachs P., Janovska P., Medrikova D., Rossmeisl M., Jilkova Z., Stefl B., Pastalkova E., Drahota Z., Houstek J., Kopecky J., Induction of muscle thermogenesis by high-fat diet in mice: association with obesity-resistance. American Journal of Physiology 2008 295 2 E356 E367 2-s2.0-52649106952 10.1152/ajpendo.90256.2008
123. Suchankova G., Tekle M., Saha A. K., Ruderman N. B., Clarke S. D., Gettys T. W., Dietary polyunsaturated fatty acids enhance hepatic AMP-activated protein kinase activity in rats. Biochemical and Biophysical Research Communications 2005 326 4 851 858 2-s2.0-10644249187 10.1016/j.bbrc.2004.11.114 (Pubitemid 39655997)
124. Wang M.-Y., Unger R. H., Role of PP2C in cardiac lipid accumulation in obese rodents and its prevention by troglitazone. American Journal of Physiology 2005 288 1 E216 E221 2-s2.0-11144283125 10.1152/ajpendo.00004.2004 (Pubitemid 40023810)
125. Flachs P., Mohamed-Ali V., Horakova O., Rossmeisl M., Hosseinzadeh-Attar M. J., Hensler M., Ruzickova J., Kopecky J., Polyunsaturated fatty acids of marine origin induce adiponectin in mice fed a high-fat diet. Diabetologia 2006 49 2 394 397 2-s2.0-31844451413 10.1007/s00125-005-0053-y (Pubitemid 43185410)
126. Wang L. -S., Huang Y. -W., Sugimoto Y., Liu S., Chang H. -L., Ye W., Shu S., Lin Y. C., lin.15@osu.edu Conjugated linoleic acid (CLA) up-regulates the estrogen-regulated cancer suppressor gene,protein tyrosine phosphatase gamma (PTPgama),in human breast cells. Anticancer Research 2006 26 1 27 34 (Pubitemid 43206056)
127. Kritchevsky D., Tepper S. A., Wright S., Czarnecki S. K., Wilson T. A., Nicolosi R. J., Conjugated linoleic acid isomer effects in atherosclerosis: growth and regression of lesions. Lipids 2004 39 7 611 616 2-s2.0-8444224260 10.1007/s11745-004-1273-8 (Pubitemid 39488878)
128. So M. H. H., Tse I. M. Y., Li E. T. S., Dietary fat concentration influences the effects of trans-10, cis-12 conjugated linoleic acid on temporal patterns of energy Intake and Hypothalamic expression of appetite-controlling genes in Mice. Journal of Nutrition 2009 139 1 145 151 2-s2.0-58649117155 10.3945/jn.108.093849
129. Beauvieux M.-C., Roumes H., Robert N., Gin H., Rigalleau V., Gallis J.-L., Butyrate ingestion improves hepatic glycogen storage in the re-fed rat. BMC Physiology 2008 8 1, article 19 2-s2.0-54049116267 10.1186/1472-6793-8-19
130. Sakakibara S., Yamauchi T., Oshima Y., Tsukamoto Y., Kadowaki T., Acetic acid activates hepatic AMPK and reduces hyperglycemia in diabetic KK-A(y) mice. Biochemical and Biophysical Research Communications 2006 344 2 597 604 2-s2.0-33646101472 10.1016/j.bbrc.2006.03.176
131. Kawaguchi T., Osatomi K., Yamashita H., Kabashima T., Uyeda K., Mechanism for fatty acid sparing effect on glucose-induced transcription: regulation of carbohydrate-responsive element-binding protein by AMP-activated protein kinase. Journal of Biological Chemistry 2002 277 6 3829 3835 2-s2.0-0037040185 10.1074/jbc.M107895200 (Pubitemid 34968632)
132. Gao Z., Yin J., Zhang J., Ward R. E., Martin R. J., Lefevre M., Cefalu W. T., Ye J., Butyrate improves insulin sensitivity and increases energy expenditure in mice. Diabetes 2009 58 7 1509 1517 2-s2.0-67649238355 10.2337/db08-1637
133. Warren J. M., Jeya C., Children low glycemic index breakfasts and reduced food intake in preadolescent. Pediatrics 2003 112 5 e414 2-s2.0-19244384292
134. Ford H., Frost G., g.frost@imperial.ac.uk Glycaemic index, appetite and body weight. Proceedings of the Nutrition Society 2010 69 2 199 203 10.1017/S0029665110000091
135. Cantó C., Gerhart-Hines Z., Feige J. N., Lagouge M., Noriega L., Milne J. C., Elliott P. J., Puigserver P., Auwerx J., AMPK regulates energy expenditure by modulating NAD + metabolism and SIRT1 activity. Nature 2009 458 7241 1056 1060 2-s2.0-67349276169 10.1038/nature07813
136. Blander G., Guarente L., The Sir2 family of protein deacetylases. Annual Review of Biochemistry 2004 73 417 435 2-s2.0-3943054839 10.1146/annurev. biochem.73.011303.073651 (Pubitemid 39050375)
137. Fukuhara A., Matsuda M., Nishizawa M., Segawa K., Tanaka M., Kishimoto K., Matsuki Y., Murakami M., Ichisaka T., Murakami H., Watanabe E., Takagi T., Akiyoshi M., Ohtsubo T., Kihara S., Yamashita S., Makishima M., Funahashi T., Yamanaka S., Hiramatsu R., Matsuzawa Y., Shimomura I., Visfatin: a protein secreted by visceral fat that Mimics the effects of insulin. Science 2005 307 5708 426 430 2-s2.0-19944433652 10.1126/science.1097243 (Pubitemid 40139988)
138. Fulco M., Cen Y., Zhao P., Hoffman E. P., McBurney M. W., Sauve A. A., Sartorelli V., Glucose restriction inhibits skeletal myoblast differentiation by activating SIRT1 through AMPK-mediated regulation of Nampt. Developmental Cell 2008 14 5 661 673 2-s2.0-43049121395 10.1016/j.devcel.2008.02.004 (Pubitemid 351622608)
139. Fulco M., Sartorelli V., Comparing and contrasting the roles of AMPK and SIRT1 in metabolic tissues. Cell Cycle 2008 7 23 3669 3679 2-s2.0-57349169258
140. Moller K., Krogh-Madsen R., Weight loss with a low-carbohydrate, Mediterranean, or low-fat diet. New England Journal of Medicine 2008 359 20 2170
141. Halton T. L., Hu F. B., The effects of high protein diets on thermogenesis, satiety and weight loss: a critical review. Journal of the American College of Nutrition 2004 23 5 373 385 2-s2.0-14644413174
142. Gietzen D. W., Hao S., Anthony T. G., Mechanisms of food intake repression in indispensable amino acid deficiency. Annual Review of Nutrition 2007 27 63 78 2-s2.0-36048985768 10.1146/annurev.nutr.27.061406.093726 (Pubitemid 351373348)
143. Potier M., Darcel N., Tomé D., Protein, amino acids and the control of food intake. Current Opinion in Clinical Nutrition and Metabolic Care 2009 12 1 54 58 2-s2.0-58149141517 10.1097/MCO.0b013e32831b9e01
144. Halford J. C. G., Harrold J. A., Boyland E. J., Lawton C. L., Blundell J. E., Serotonergic drugs: effects on appetite expression and use for the treatment of obesity. Drugs 2007 67 1 27 55 2-s2.0-33846246036 10.2165/00003495-200767010-00004 (Pubitemid 46105086)
145. Morrison C. D., Xi A., White C. L., Ye J., Martin R. J., Amino acids inhibit Agrp gene expression via an mTOR-dependent mechanism. American Journal of Physiology 2007 293 1 E165 E171 2-s2.0-34547121196 10.1152/ajpendo.00675.2006 (Pubitemid 47105930)
146. Ropelle E. R., Pauli J. R., Fernandes M. F. A., Rocco S. A., Marin R. M., Morari J., Souza K. K., Dias M. M., Gomes-Marcondes M. C., Gontijo J. A. R., Franchini K. G., Velloso L. A., Saad M. J. A., Carvalheira J. B. C., A central role for neuronal AMP-activated protein kinase (AMPK) and mammalian target of rapamyein (mTOR) in high-protein diet-induced weight loss. Diabetes 2008 57 3 594 605 2-s2.0-40949150324 10.2337/db07-0573
147. Gleason C. E., Lu D., Witters L. A., Newgard C. B., Birnbaum M. J., The role of AMPK and mTOR in nutrient sensing in pancreatic β -cells. Journal of Biological Chemistry 2007 282 14 10341 10351 2-s2.0-34249850161 10.1074/jbc.M610631200 (Pubitemid 47093450)
148. Grover J. K., Yadav S. P., Pharmacological actions and potential uses of Momordica charantia: a review. Journal of Ethnopharmacology 2004 93 1 123 132 2-s2.0-2942538292 10.1016/j.jep.2004.03.035 (Pubitemid 38739282)
149. Tan M. -J., Ye J. -M., Turner N., Hohnen-Behrens C., Ke C. -Q., Tang C. -P., Chen T., Weiss H. -C., Gesing E. -R., Rowland A., James D. E., d.james@garvan.org.au Ye Y., yye@mail.shcnc.ac.cn Antidiabetic activities of triterpenoids isolated from bitter melon associated with activation of the AMPK pathway. Chemistry and Biology 2008 15 3 263 273 10.1016/j.chembiol.2008.01.013 (Pubitemid 351381992)
150. Baur J. A., Pearson K. J., Price N. L., Jamieson H. A., Lerin C., Kalra A., Prabhu V. V., Allard J. S., Lopez-Lluch G., Lewis K., Pistell P. J., Poosala S., Becker K. G., Boss O., Gwinn D., Wang M., Ramaswamy S., Fishbein K. W., Spencer R. G., Lakatta E. G., Le Couteur D., Shaw R. J., Navas P., Puigserver P., Ingram D. K., De Cabo R., Sinclair D. A., Resveratrol improves health and survival of mice on a high-calorie diet. Nature 2006 444 7117 337 342 2-s2.0-33751072349 10.1038/nature05354 (Pubitemid 44764104)
151. Lagouge M., Argmann C., Gerhart-Hines Z., Meziane H., Lerin C., Daussin F., Messadeq N., Milne J., Lambert P., Elliott P., Geny B., Laakso M., Puigserver P., Auwerx J., Resveratrol improves mitochondrial function and protects against metabolic disease by activating SIRT1 and PGC-1 α Cell 2006 127 6 1109 1122 2-s2.0-33845399894 10.1016/j.cell.2006.11.013 (Pubitemid 44894520)
152. Leng S.-H., Lu F.-E., Xu L.-J., Therapeutic effects of berberine in impaired glucose tolerance rats and its influence on insulin secretion. Acta Pharmacologica Sinica 2004 25 4 496 502 2-s2.0-1842708890 (Pubitemid 38470422)
153. Kim W. S., Lee Y. S., Cha S. H., Jeong H. W., Choe S. S., Lee M.-R., Oh G. T., Park H.-S., Lee K.-U., Lane M. D., Kim J. B., Berberine improves lipid dysregulation in obesity by controlling central and peripheral AMPK activity. American Journal of Physiology 2009 296 4 E812 E819 2-s2.0-65649089100 10.1152/ajpendo.90710.2008
154. Lee Y. S., Kim W. S., Kim K. H., Yoon M. J., Cho H. J., Shen Y., Ye J.-M., Lee C. H., Oh W. K., Kim C. T., Hohnen-Behrens C., Gosby A., Kraegen E. W., James D. E., Kim J. B., Berberine, a natural plant product, activates AMP-activated protein kinase with beneficial metabolic effects in diabetic and insulin-resistant states. Diabetes 2006 55 8 2256 2264 2-s2.0-33749336146 10.2337/db06-0006 (Pubitemid 44743622)
155. Gidding S. S., Dennison B. A., Birch L. L., Daniels S. R., Gilman M. W., Lichtenstein A. H., Rattay K. T., Steinberger J., Stettler N., Dietary recommendations for children and adolescents: a guide for practitioners. Pediatrics 2006 117 2 544 559 10.1542/peds.2005-2374 (Pubitemid 46074650)
156. Gibson L. J., Peto J., Warren J. M., dos Santos Silva I., Lack of evidence on diets for obesity for children: a systematic review. International Journal of Epidemiology 2006 35 6 1544 1552 2-s2.0-33846647020 10.1093/ije/dyl208 (Pubitemid 46178933)
157. Mendieta-Zerón H., López M., Diéguez C., Hypothalamic regulation of feeding by nutrients and metabolic state. Revista Espanola de Obesidad 2007 5 6 351 362 2-s2.0-39149143294 (Pubitemid 351251276)
158. Spear B. A., Barlow S. E., Ervin C., Ludwig D. S., Saelens B. E., Schetzina K. E., Taveras E. M., Recommendations for treatment of child and adolescent overweight and obesity. Pediatrics 2007 120 S254 288 2-s2.0-38449107149 10.1542/peds.2007-2329F
159. August G. P., Caprio S., Fennoy I., Freemark M., Kaufman F. R., Lustig R. H., Silverstein J. H., Speiser P. W., Styne D. M., Montori V. M., Prevention and treatment of pediatric obesity: an endocrine society clinical practice guideline based on expert opinion. Journal of Clinical Endocrinology and Metabolism 2008 93 12 4576 4599 2-s2.0-41849141673 10.1210/jc.2007-2458
160. Oude L. H., Baur L., Jansen H., Shrewsbury V. A., O'Malley C., Stolk R. P., Summerbell C. D., Interventions for treating obesity in children. Cochrane Database of Systematic Reviews 2009 21 1 CD001872 10.1002/14651858.CD001872 2-s2.0-62449279686
161. McDuffie J. R., Calis K. A., Uwaifo G. I., Sebring N. G., Fallon E. M., Hubbard V. S., Yanovski J. A., Three-month tolerability of orlistat in adolescents with obesity-related comorbid conditions. Obesity Research 2002 10 7 642 650 2-s2.0-0036633087 (Pubitemid 135688263)
162. Norgren S., Danielsson P., Jurold R., Lötborn M., Marcus C., Orlistat treatment in obese prepubertal children: a pilot study. Acta Paediatrica, International Journal of Paediatrics 2003 92 6 666 670 2-s2.0-0042375748 10.1080/08035250310002353 (Pubitemid 37088673)
163. Leung W. Y. S., Thomas G. N., Chan J. C. N., Tomlinson B., Weight management and current options in pharmacotherapy: orlistat and sibutramine. Clinical Therapeutics 2003 25 1 58 80 2-s2.0-0037279371 10.1016/S0149-2918(03) 90009-9 (Pubitemid 36206738)
164. Berkowitz R. I., Fujioka K., Daniels S. R., Hoppin A. G., Owen S., Perry A. C., Sothern M. S., Renz C. L., Pirner M. A., Walch J. K., Jasinsky O., Hewkin A. C., Blakesley V. A., Effects of sibutramine treatment in obese adolescents: a randomized trial. Annals of Internal Medicine 2006 145 2 81 90 2-s2.0-33746664768 (Pubitemid 46780581)
165. Zhou G., Myers R., Li Y., Chen Y., Shen X., Fenyk-Melody J., Wu M., Ventre J., Doebber T., Fujii N., Musi N., Hirshman M. F., Goodyear L. J., Moller D. E., Role of AMP-activated protein kinase in mechanism of metformin action. Journal of Clinical Investigation 2001 108 8 1167 1174 2-s2.0-0034773404 10.1172/JCI200113505 (Pubitemid 32995375)
166. Marchesini G., Brizi M., Bianchi G., Tomassetti S., Zoli M., Melchionda N., Metformin in non-alcoholic steatohepatitis. The Lancet 2001 358 9285 893 894 2-s2.0-0035883890 10.1016/S0140-6736(01)06042-1 (Pubitemid 32900577)
167. Pasquali R., Gambineri A., Biscotti D., Vicennati V., Gagliardi L., Colitta D., Fiorini S., Cognigni G. E., Filicori M., Morselli-Labate A. M., Effect of long-term treatment with metformin added to hypocaloric diet on body composition, fat distribution, and androgen and insulin levels in abdominally obese women with and without the polycystic ovary syndrome. Journal of Clinical Endocrinology and Metabolism 2000 85 8 2767 2774 2-s2.0-17744400090 10.1210/jc.85.8.2767 (Pubitemid 32269149)
168. Freemark M., Bursey D., The effects of metformin on body mass index and glucose tolerance in obese adolescents with fasting hyperinsulinemia and a family history of type 2 diabetes. Pediatrics 2001 107 4 e55 2-s2.0-0035321014
169. Srinivasan S., Ambler G. R., Baur L. A., Garnett S. P., Tepsa M., Yap F., Ward G. M., Cowell C. T., Randomized, controlled trial of metformin for obesity and insulin resistance in children and adolescents: improvement in body composition and fasting insulin. Journal of Clinical Endocrinology and Metabolism 2006 91 6 2074 2080 2-s2.0-33744959061 10.1210/jc.2006-0241 (Pubitemid 43854985)
170. Burgert T. S., Duran E. J., Goldberg-gell R., Dziura J., Yeckel C. W., Katz S., Tamborlane W. V., Caprio S., Short-term metabolic and cardiovascular effects of metformin in markedly obese adolescents with normal glucose tolerance. Pediatric Diabetes 2008 9 6 567 576 2-s2.0-56649107790 10.1111/j.1399-5448.2008.00434.x
171. Love-Osborne K., Sheeder J., Zeitler P., Addition of metformin to a lifestyle modification program in adolescents with insulin resistance. Journal of Pediatrics 2008 152 6 817 822 2-s2.0-43549109197 10.1016/j.jpeds.2008.01.018
172. Casteels K., Kristina.casteels@uzleuven.be Fieuws S., van Helvoirt M., Verpoorten C., Goemans N., Coudyzer W., Loeckx D., de Zegher F., Metformin therapy to reduce weight gain and visceral adiposity in children and adolescents with neurogenic or myogenic motor deficit. Pediatric Diabetes 2010 11 1 61 69 10.1111/j.1399-5448.2009.00512.x
173. Wilson D. M., dwilson@stanford.edu Abrams S. H., Aye T., Lee P. D.K., Lenders C., Lustig R. H., Osganian S. V., Feldman H. A., Fechner P., Robinson T., Buckingham B., Esrey T., McNeil K., Sorensen B., Wilson K., Davis J., Klish W., Abrams S., Holt P., Edwards C., Howard L., Gitelman S., Wertz M., Breland J., Lihatsh T., Haddal A., Cohen P., Shupien S., Mooney J., Khanukhova E., Cohen H., Taylor G., Duggan C., Nurko S., Sweeney C., Zhang K., McCarthy M., Wake M., Filip-Dhima R., Prober C., Urbanek K., Kim A., Kelley A., Crabtree C., Styne D., Gottschalk M., Hale D., Krause-Steinrauf H., Metformin extended release treatment of adolescent obesity. Archives of Pediatrics and Adolescent Medicine 2010 164 2 116 123 10.1001/archpediatrics.2009.264
174. Wilson A. J., awils29@uwo.ca Prapavessis H., hprapave@uwo.ca Jung M. E., mjung32@uwo.ca Cramp A. G., acramp2@uwo.ca Vascotto J., joy.vascotto@lhsc.on.ca Lenhardt L., larissa.lenhardt@lhsc.on.ca Shoemaker J. K., kshoemak@uwo.ca Watson M., margaret.watson@lhsc.on.ca Robinson T., tracy.robinson@lhsc.on.ca Clarson C. L., cheril.clarson@lhsc.on.ca Lifestyle modification and metformin as long-term treatment options for obese adolescents: study protocol. BMC Public Health 2009 9, article 434 10.1186/1471-2458-9-434
175. Goran M. I., Reynolds K. D., Lindquist C. H., Role of physical activity in the prevention of obesity in children. International Journal of Obesity 1999 23 3 S18 S33 2-s2.0-0032950184 (Pubitemid 29224506)
176. Daniels S. R., Jacobson M. S., McCrindle B. W., Eckel R. H., Sanner B. M., American heart association childhood obesity: research summit. Circulation 2009 119 15 2114 2123 2-s2.0-65449125061 10.1161/CIRCULATIONAHA.109.192215
177. Caspersen C. J., Powell K. E., Christenson G., Physical activity, exercise and physical fitness: definitions and distinctions for health-related research. Public Health Reports 1985 100 2 126 131 2-s2.0-0021798918 (Pubitemid 15064369)
178. Dunn A. L., Andersen R. E., Jakicic J. M., Lifestyle physical activity interventions history, short- and long-term effects, and recommendations. American Journal of Preventive Medicine 1998 15 4 398 412 2-s2.0-0031797461 10.1016/S0749-3797(98)00084-1 (Pubitemid 28521124)
179. Baird J., Fisher D., Lucas P., Kleijnen J., Roberts H., Law C., Being big or growing fast: systematic review of size and growth in infancy and later obesity. British Medical Journal 2005 331 7522 929 931 2-s2.0-27144545771 10.1136/bmj.38586.411273.E0 (Pubitemid 41510845)
180. Stettler N., Stallings V. A., Troxel A. B., Zhao J., Schinnar R., Nelson S. E., Ziegler E. E., Strom B. L., Weight gain in the first week of life and overweight in adulthood: a cohort study of European American subjects fed infant formula. Circulation 2005 111 15 1897 1903 2-s2.0-17644403205 10.1161/01.CIR.0000161797.67671.A7 (Pubitemid 40570209)
181. Mayer-Davis E. J., Rifas-Shiman S. L., Zhou L., Hu F. B., Colditz G. A., Gillman M. W., Breast-feeding and risk for childhood obesity: does maternal diabetes or obesity status matter? Diabetes Care 2006 29 10 2231 2237 2-s2.0-33845428865 10.2337/dc06-0974 (Pubitemid 44899857)
182. Freedman D. S., Kettel Khan L., Serdula M. K., Srinivasan S. R., Berenson G. S., BMI rebound, childhood height and obesity among adults: the Bogalusa heart study. International Journal of Obesity 2001 25 4 543 549 2-s2.0-0035068277 10.1038/sj.ijo.0801581 (Pubitemid 32293564)
183. Taylor R. W., Grant A. M., Goulding A., ailsa.goulding@stonebow.otago.ac. nz Williams S. M., Early adiposity rebound: review of papers linking this to subsequent obesity in children and adults. Current Opinion in Clinical Nutrition and Metabolic Care 2005 8 6 607 612 (Pubitemid 41586000)
184. Cole T. J., Children grow and horses race: is the adiposity rebound a critical period for later obesity? BMC Pediatrics 2004 4, article no. 6 2-s2.0-2642533732 10.1186/1471-2431-4-6 (Pubitemid 38729227)
185. Eriksson J. G., Forsén T., Tuomilehto J., Osmond C., Barker D. J. P., Early adiposity rebound in childhood and risk of Type 2 diabetes in adult life. Diabetologia 2003 46 2 190 194 2-s2.0-0037300129 (Pubitemid 36343882)
186. Williams S., Dickson N., Early growth, menarche, and adiposity rebound. The Lancet 2002 359 9306 580 581 2-s2.0-0037116892 10.1016/S0140-6736(02)07715-2 (Pubitemid 34178443)
187. Rolland-Cachera M. F., Deheeger M., Maillot M., Bellisle F., Early adiposity rebound: causes and consequences for obesity in children and adults. International Journal of Obesity 2006 30 4 S11 S17 2-s2.0-33751511506 10.1038/sj.ijo.0803514 (Pubitemid 44837544)
188. Rolland-Cachera M. F., Deheeger M., Guilloud-Bataille M., Avons P., Patois E., Sempé M., Tracking the development of adiposity from one month of age to adulthood. Annals of Human Biology 1987 14 3 219 229 2-s2.0-0023336996
189. Williams S. M., Goulding A., Patterns of gowth associated with the timing of adiposity rebound. Obesity 2009 17 2 335 341 2-s2.0-58849086620 10.1038/oby.2008.547
190. Williams S., Dickson N., Early growth, menarche, and adiposity rebound. The Lancet 2002 359 9306 580 581 2-s2.0-0037116892 10.1016/S0140-6736(02)07715-2 (Pubitemid 34178443)
191. Williams S. M., Goulding A., Early adiposity rebound is an important predictor of later obesity. Obesity 2009 17 7 1310 2-s2.0-67649806857 10.1038/oby.2009.104
192. Whitaker R. C., Pepe M. S., Wright J. A., Seidel K. D., Dietz W. H., Early adiposity rebound and the risk of adult obesity. Pediatrics 1998 101 3 e5 2-s2.0-0032018052
193. Eriksson J. G., Forsén T., Tuomilehto J., Winter P. D., Osmond C., Barker D. J. P., Catch-up growth in childhood and death from coronary heart disease: longitudinal study. British Medical Journal 1999 318 7181 427 431 2-s2.0-0033550681 (Pubitemid 29192114)
194. Velasquez-Mieyer P., Perez-Faustineli S., Cowan P. A., Identifying children at risk for obesity, type 2 diabetes, and cardiovascular disease. Diabetes Spectrum 2005 18 4 213 220 2-s2.0-27844566261 10.2337/diaspect.18.4.213 (Pubitemid 41642299)
195. Nader P. R., O'Brien M., Houts R., Bradley R., Belsky J., Crosnoe R., Friedman S., Mei Z., Susman E. J., Identifying risk for obesity in early childhood. Pediatrics 2006 118 3 e594 e601 2-s2.0-33749072319 10.1542/peds.2005-2801 (Pubitemid 46089984)
196. Lawlor D. A., d.a.lawlor@bristol.ac.uk Chaturvedi N., Treatment and prevention of obesity-are there critical periods for intervention? International Journal of Epidemiology 2006 35 1 3 9 10.1093/ije/dyi309 (Pubitemid 43205431)
197. Moore L. L., Gao D., Bradlee M. L., Cupples L. A., Sundarajan-Ramamurti A., Proctor M. H., Hood M. Y., Singer M. R., Ellison R. C., Does early physical activity predict body fat change throughout childhood? Preventive Medicine 2003 37 1 10 17 2-s2.0-0038173373 10.1016/S0091-7435(03)00048-3 (Pubitemid 36687860)
198. Physical Activity and Health: A Report from the Surgeon General 1996 Atlanta, Ga, USA US Department of Health and Human Services
199. Moore L. L., Nguyen U. -S.D.T., Rothman K. J., Cupples L. A., Ellison R. C., Preschool physical activity level and change in body fatness in young children: the Framingham Children's Study. American Journal of Epidemiology 1995 142 9 982 988
200. Proctor M. H., Moore L. L., Gao D., Cupples L. A., Bradlee M. L., Hood M. Y., Ellison R. C., Television viewing and change in body fat from preschool to early adolescence: the Framingham Children's Study. International Journal of Obesity 2003 27 7 827 833 2-s2.0-0038005020 10.1038/sj.ijo.0802294 (Pubitemid 36819541)
201. Singer M. R., Moore L. L., Garrahie E. J., Ellison R. C., The tracking of nutrient intake in young children: the Framingham Children's Study. American Journal of Public Health 1995 85 12 1673 1677 2-s2.0-0029565892 (Pubitemid 26002601)
202. Lim C. T., Kola B., Korbonits M., AMPK as a mediator of hormonal signaling. Journal of Molecular Endocrinology 2010 44 87 97
203. Wellen K. E., Hotamisligil G. S., Inflammation, stress, and diabetes. Journal of Clinical Investigation 2005 115 5 1111 1119 2-s2.0-18244370762 10.1172/JCI200525102 (Pubitemid 40629025)
204. Schwarzenberg S. J., Sinaiko A. R., Obesity and inflammation in children. Paediatric Respiratory Reviews 2006 7 4 239 246 2-s2.0-33750604987 10.1016/j.prrv.2006.08.002 (Pubitemid 44689278)
205. Visser M., Bouter L. M., McQuillan G. M., Wener M. H., Harris T. B., Low-grade systemic inflammation in overweight children. Pediatrics 2001 107 1 13 20 2-s2.0-0035234153
206. Weiss R., Dziura J., Burgert T. S., Tamborlane W. V., Taksali S. E., Yeckel C. W., Allen K., Lopes M., Savoye M., Morrison J., Sherwin R. S., Caprio S., Obesity and the metabolic syndrome in children and adolescents. New England Journal of Medicine 2004 350 23 2362 2374 2-s2.0-2542548063 10.1056/NEJMoa031049 (Pubitemid 38702847)
207. Gilardini L., McTernan P. G., Girola A., da Silva N. F., Alberti L., Kumar S., Invitti C., invitti@auxologico.it Adiponectin is a candidate marker of metabolic syndrome in obese children and adolescents. Atherosclerosis 2006 189 2 401 407 10.1016/j.atherosclerosis.2005.12.021 (Pubitemid 44634487)
208. Winer J. C., Zern T. L., Taksali S. E., Dziura J., Cali A. M. G., Wollschlager M., Seyal A. A., Weiss R., Burgert T. S., Caprio S., Adiponectin in childhood and adolescent obesity and its association with inflammatory markers and components of the metabolic syndrome. Journal of Clinical Endocrinology and Metabolism 2006 91 11 4415 4423 2-s2.0-33751512005 10.1210/jc.2006-0733 (Pubitemid 44833417)
209. Herder C., Schneitler S., Rathmann W., Haastert B., Schneitler H., Winkler H., Bredahl R., Hahnloser E., Martin S., Low-grade inflammation, obesity, and insulin resistance in adolescents. Journal of Clinical Endocrinology and Metabolism 2007 92 12 4569 4574 2-s2.0-36849013098 10.1210/jc.2007-0955 (Pubitemid 350223428)
210. Garanty-Bogacka B., Syrenicz M., Syrenicz A., Gebala A., Lulka D., Walczak M., Serum markers of inflammation and endothelial activation in children with obesity-related hypertension. Neuroendocrinology Letters 2005 26 3 242 246 2-s2.0-22144475156 (Pubitemid 40975104)
211. Reinehr T., t.reinehr@kinderklinik-datteln.de Stoffel-Wagner B., Roth C. L., Andler W., High-sensitive C-reactive protein, tumor necrosis factor α and cardiovascular risk factors before and after weight loss in obese children. Metabolism 2005 54 9 1155 1161 10.1016/j.metabol.2005.03.022 (Pubitemid 41206875)
212. Febbraio M. A., Pedersen B. K., bkp@rh.dk Muscle-derived interleukin-6: mechanisms for activation and possible biological roles. FASEB Journal 2002 16 11 1335 1347 10.1096/fj.01-0876rev (Pubitemid 34913306)
213. Pedersen B. K., Hoffman-Goetz L., Exercise and the immune system: regulation, integration, and adaptation. Physiological Reviews 2000 80 3 1055 1081 2-s2.0-0033922490 (Pubitemid 30452011)
214. Anon, Infant and adult obesity. The Lancet 1974 1 7845 17 18 2-s2.0-0015965778
215. Nestle M., Jacobson M. F., Halting the obesity epidemic: a public policy approach. Public Health Reports 2000 115 1 12 24 2-s2.0-0034116081 (Pubitemid 30146482)
216. Department of Health and Human Services (US), Healthy People 2010: Understanding and Improving Health 2000 Washington, DC, USA Government Printing Office. Conference edition
217. Barlow S. E., Expert committee recommendations regarding the prevention, assessment, and treatment of child and adolescent overweight and obesity: summary report. Pediatrics 2007 120 S164 192 2-s2.0-38449095758 10.1542/peds.2007-2329C
218. Brennan L., leah.brennan@rmit.edu.au Walkley J., Fraser S. F., Greenway K., Wilks R., Motivational interviewing and cognitive behaviour therapy in the treatment of adolescent overweight and obesity: study design and methodology. Contemporary Clinical Trials 2008 29 3 359 375 10.1016/j.cct.2007.09.001 (Pubitemid 351509804)
219. Mo-Suwan L., Pongprapai S., Junjana C., Puetpaiboon A., Effects of a controlled trial of a school-based exercise program on the obesity indexes of preschool children. American Journal of Clinical Nutrition 1998 68 5 1006 1011 2-s2.0-0031786525 (Pubitemid 28493959)
220. Carrel A. L., Clark R. R., Peterson S. E., Nemeth B. A., Sullivan J., Allen D. B., Improvement of fitness, body composition, and insulin sensitivity in overweight children in a school-based exercise program: a randomized, controlled study. Archives of Pediatrics and Adolescent Medicine 2005 159 10 963 968 2-s2.0-26444573105 10.1001/archpedi.159.10.963 (Pubitemid 41423336)
221. Dehghan M., Akhtar-Danesh N., Merchant A. T., Childhood obesity, prevalence and prevention. Nutrition Journal 2005 4, article 24 2-s2.0-24944480091 10.1186/1475-2891-4-24 (Pubitemid 41309077)
222. Mallare J. T., Karabell A. H., Velasquez-Mieyer P., Stander S. R. S., Christensen M. L., Current and future treatment of metabolic syndrome and type 2 diabetes in children and adolescents. Diabetes Spectrum 2005 18 4 220 228 2-s2.0-27844456867 10.2337/diaspect.18.4.220 (Pubitemid 41642300)