Obestatin promotes survival of pancreatic β-cells and human islets and induces expression of genes involved in the regulation of β-cell mass and function

Diabetes

Volumn 57, Issue 4, 2008, Pages 967-979

  Granata, Riccarda ^a   Settanni, Fabio ^a   Gallo, Davide ^a   Trovato, Letizia ^a   Biancone, Luigi ^a   Cantaluppi, Vincenzo ^a   Nano, Rita ^b   Annunziata, Marta ^a   Campiglia, Pietro ^c   Arnoletti, Elisa ^d   Ghé, Corrado ^d   Volante, Marco ^d   Papotti, Mauro ^d   Muccioli, Giampiero ^d   Ghigo, Ezio ^a  

^a UNIVERSITY OF TURIN   (Italy)

^b VITA SALUTE SAN RAFFAELE UNIVERSITY   (Italy)

^c UNIVERSITY OF SALERNO   (Italy)

^d UNIVERSITY OF TURIN   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ADENYLATE CYCLASE; CYCLIC AMP; GAMMA INTERFERON; GHRELIN; GLUCAGON LIKE PEPTIDE 1 RECEPTOR; GLUCOKINASE; HISTIDYL DEXTRO TRYPTOPHYLALANYLTRYPTOPHYL DEXTRO PHENYLALANYLLYSINAMIDE; HOMEODOMAIN PROTEIN; HORMONE ANTIBODY; HORMONE RECEPTOR BLOCKING AGENT; INSULIN; INSULIN RECEPTOR SUBSTRATE 2; INTERLEUKIN 1BETA; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; OBESTATIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; TUMOR NECROSIS FACTOR ALPHA; CASPASE 3; GLUCAGON LIKE PEPTIDE 1; INSULIN RECEPTOR SUBSTRATE 2 PROTEIN; INSULIN RECEPTOR SUBSTRATE-2 PROTEIN; OBESTATIN, HUMAN; PEPTIDE HORMONE; PHOSPHOPROTEIN; SIGNAL PEPTIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; APOPTOSIS; ARTICLE; BINDING SITE; CELL FUNCTION; CELL INTERACTION; CELL PROLIFERATION; CELL SURVIVAL; CELL VIABILITY; CONCENTRATION RESPONSE; CONTROLLED STUDY; ENZYME INDUCTION; GENE EXPRESSION REGULATION; HOMEOBOX; HUMAN; HUMAN TISSUE; IMMUNOREACTIVITY; INSULIN RELEASE; NONHUMAN; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION; UPREGULATION; CELL DIVISION; CELL MEMBRANE; CULTURE TECHNIQUE; CYTOLOGY; DRUG EFFECT; METABOLISM; PHYSIOLOGY; SECRETION;

CASPASE 3; CELL CULTURE TECHNIQUES; CELL DIVISION; CELL MEMBRANE; CELL SURVIVAL; CYCLIC AMP; GENE EXPRESSION REGULATION; GHRELIN; GLUCAGON-LIKE PEPTIDE 1; HUMANS; INSULIN-SECRETING CELLS; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; ISLETS OF LANGERHANS; PEPTIDE HORMONES; PHOSPHOPROTEINS;

EID: 42449124783     PISSN: 00121797     EISSN: 1939327X     Source Type: Journal    
DOI: 10.2337/db07-1104     Document Type: Article

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