Congenital leptin deficiency due to homozygosity for the Δ133G mutation: Report of another case and evaluation of response to four years of leptin therapy

Journal of Clinical Endocrinology and Metabolism

Volumn 89, Issue 10, 2004, Pages 4821-4826

  Gibson, William T ^a   Farooqi, I Sadaf ^a   Moreau, Mary ^b   DePaoli, Alex M ^c   Lawrence, Elizabeth ^c   O'Rahilly, Stephen ^a   Trussell, Rebecca A ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ALBERTA CHILDREN'S HOSPITAL   (Canada)

^c AMGEN INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BRONCHODILATING AGENT; CORTICOSTEROID; RECOMBINANT LEPTIN; THYROXINE;

ANAMNESIS; ARTICLE; ASTHMA; BIOCHEMISTRY; BODY FAT; CASE REPORT; CLINICAL FEATURE; DRUG BLOOD LEVEL; DRUG EFFECT; DRUG EFFICACY; DRUG SAFETY; FEMALE; GENE MUTATION; HOMOZYGOSITY; HORMONE DEFICIENCY; HUMAN; HYPERINSULINEMIA; HYPERLIPIDEMIA; HYPERPHAGIA; LABORATORY TEST; OBESITY; PRIORITY JOURNAL; SCHOOL CHILD; THYROID GLAND;

BODY COMPOSITION; BODY WEIGHT; BONE DEVELOPMENT; CHILD; CHILD, PRESCHOOL; FEMALE; FOLLICLE STIMULATING HORMONE; HOMOZYGOTE; HUMANS; HYPOTHYROIDISM; INSULIN; LEPTIN; LEUKOCYTE COUNT; LIPIDS; LUTEINIZING HORMONE; OBESITY; POINT MUTATION;

EID: 6344221594     PISSN: 0021972X     EISSN: None     Source Type: Journal    
DOI: 10.1210/jc.2004-0376     Document Type: Article

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