Nutritional programming affects hypothalamic organization and early response to leptin

Endocrinology

Volumn 151, Issue 2, 2010, Pages 702-713

  Coupé, Bérengère ^a   Amarger, Valérie ^a   Grit, Isabelle ^a   Benani, Alexandre ^b   Parnet, Patricia ^a  

^a CEMAGREF   (France)

^b UNIVERSITÉ DE BOURGOGNE   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AGOUTI RELATED PROTEIN; ALPHA INTERMEDIN; LEPTIN; MESSENGER RNA; NEUROPEPTIDE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; APPETITE; ARCUATE NUCLEUS; ARTICLE; BIRTH; BLOOD LEVEL; CELL DIFFERENTIATION; CONTROLLED STUDY; CYTOSKELETON; EFFERENT NERVE; ENERGY; EPIGENETICS; GENE EXPRESSION; HOMEOSTASIS; HORMONE BLOOD LEVEL; HYPOTHALAMUS; IMMUNOREACTIVITY; INTRAUTERINE GROWTH RETARDATION; MALE; NERVE CELL DIFFERENTIATION; NONHUMAN; NUTRITION; ORGANIZATION; PERINATAL PERIOD; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RAT STRAIN; SCREENING; THALAMUS MIDLINE NUCLEUS;

AGOUTI-RELATED PROTEIN; ALPHA-MSH; ANIMALS; ARCUATE NUCLEUS; BODY WEIGHT; DNA; DNA METHYLATION; ENERGY INTAKE; FEMALE; FETAL GROWTH RETARDATION; GENE EXPRESSION REGULATION; HYPOTHALAMUS; LEPTIN; MALE; NERVE FIBERS; NERVE TISSUE PROTEINS; NEUROPEPTIDE Y; PARAVENTRICULAR HYPOTHALAMIC NUCLEUS; PRO-OPIOMELANOCORTIN; RATS; REFERENCE VALUES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA; SIGNAL TRANSDUCTION;

EID: 74949087038     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2009-0893     Document Type: Article

References (41)

1. Gluckman PD, Hanson MA, Pinal C 2005 The developmental origins of adult disease. Matern Child Nutr 1:130-141
2. Hales CN, Barker DJ 2001 The thrifty phenotype hypothesis. Br Med Bull 60:5-20
3. Barker DJ, Hales CN, Fall CH, Osmond C, Phipps K, Clark PM 1993 Type 2 (non-insulin-dependent) diabetes mellitus, hypertension and hyperlipidaemia (syndrome X): relation to reduced fetal growth. Diabetologia 36:62-67
4. Bellinger L, Lilley C, Langley-Evans SC 2004 Prenatal exposure to a maternal low-protein diet programmes a preference for high-fat foods in the young adult rat. Br J Nutr 92:513-520
5. Coupé B, Grit I, Darmaun D, Parnet P 2009 The timing of "catch-up growth" affects metabolism and appetite regulation in male rats born with intra-uterine growth restriction. Am J Physiol Regul Integr Comp Physiol 297:R813-R824
6. Breton C, Lukaszewski MA, Risold PY, Enache M, Guillemot J, Rivière G, Delahaye F, Lesage J, Dutriez-Casteloot I, Laborie C, Vieau D 2009 Maternal prenatal undernutrition alters the response of POMC neurons to energy status variation in adult male rat offspring. Am J Physiol Endocrinol Metab 296:E462-E472
7. Wynne K, Stanley S, McGowan B, Bloom S 2005 Appetite control. J Endocrinol 184:291-318
8. Ahima RS, Flier JS 2000 Leptin. Annu Rev Physiol 62:413-437
9. Sahu A 2004 A hypothalamic role in energy balance with special emphasis on leptin. Endocrinology 145:2613-2620
10. Ahima RS, Prabakaran D, Flier JS 1998 Postnatal leptin surge and regulation of circadian rhythm of leptin by feeding. Implications for energy homeostasis and neuroendocrine function. J Clin Invest 101: 1020-1027
11. Ahima RS, HilemanSM2000 Postnatal regulation of hypothalamic neuropeptide expression by leptin: implications for energy balance and body weight regulation. Regul Pept 92:1-7
12. Bouret SG, Draper SJ, Simerly RB 2004 Trophic action of leptin on hypothalamic neurons that regulate feeding. Science 304:108-110
13. Grove KL, Smith MS 2003 Ontogeny of the hypothalamic neuropeptide Y system. Physiol Behav 79:47-63
14. Bouret SG 2009 Early life origins of obesity: role of hypothalamic programming. J Pediatr Gastroenterol Nutr 48(Suppl 1):S31-S38
15. Ahima RS, Bjorbaek C, Osei S, Flier JS 1999 Regulation of neuronal and glial proteins by leptin: implications for brain development. Endocrinology 140:2755-2762
16. Garza JC, Guo M, Zhang W, Lu XY 2008 Leptin increases adult hippocampal neurogenesis in vivo and in vitro. J Biol Chem 283: 18238-18247
17. O'Malley D, MacDonald N, Mizielinska S, Connolly CN, Irving AJ, Harvey J 2007 Leptin promotes rapid dynamic changes in hippocampal dendritic morphology. Mol Cell Neurosci 35:559-572
18. Udagawa J, Hatta T, Hashimoto R, Otani H 2007 Roles of leptin in prenatal and perinatal brain development. Congenit Anom (Kyoto) 47:77-83
19. Vickers MH, Gluckman PD, Coveny AH, Hofman PL, Cutfield WS, Gertler A, Breier BH, Harris M 2005 Neonatal leptin treatment reverses developmental programming. Endocrinology 146:4211-4216
20. Delahaye F, Breton C, Risold PY, Enache M, Dutriez-Casteloot I, Laborie C, Lesage J, Vieau D 2008 Maternal perinatal undernutrition drastically reduces postnatal leptin surge and affects the development of arcuate nucleus proopiomelanocortin neurons in neonatal male rat pups. Endocrinology 149:470-475
21. Yura S, Itoh H, Sagawa N, Yamamoto H, Masuzaki H, Nakao K, Kawamura M, Takemura M, Kakui K, Ogawa Y, Fujii S 2005 Role of premature leptin surge in obesity resulting from intrauterine undernutrition. Cell Metab 1:371-378
22. Plagemann A, Harder T, Brunn M, Harder A, Roepke K, Wittrock-Staar M, Ziska T, Schellong K, Rodekamp E, Melchior K, Dudenhausen JW 2009 Hypothalamic proopiomelanocortin promoter methylation becomes altered by early overfeeding: an epigenetic model of obesity and the metabolic syndrome. J Physiol 587: 4963-4976
23. Fança-Berthon P, Michel C, Pagniez A, Rival M, Van Seuningen I, Darmaun D, Hoebler C 2009 Intrauterine growth restriction alters postnatal colonic barrier maturation in rats. Pediatr Res 66:47-52
24. Paxinos G, Watson C 2005 The rat brain in stereotaxic coordinates. 5th ed. New York: Elsevier Academic Press
25. -ΔΔCT method. Methods 25:402-408
26. Münzberg H, Huo L, Nillni EA, Hollenberg AN, Bjørbaek C 2003 Role of signal transducer and activator of transcription 3 in regulation of hypothalamic proopiomelanocortin gene expression by leptin. Endocrinology 144:2121-2131
27. Shu SY, Ju G, FanLZ1988 The glucose oxidase-DAB-nickel method in peroxidase histochemistry of the nervous system. Neurosci Lett 85:169-171
28. Li LC, Dahiya R 2002 MethPrimer: designing primers for methylation PCRs. Bioinformatics 18:1427-1431
29. Frontini A, Bertolotti P, Tonello C, Valerio A, Nisoli E, Cinti S, Giordano A 2008 Leptin-dependent STAT3 phosphorylation in postnatal mouse hypothalamus. Brain Res 1215:105-115
30. de Souza FS, Santangelo AM, Bumaschny V, Avale ME, Smart JL, Low MJ, Rubinstein M 2005 Identification of neuronal enhancers of the proopiomelanocortin gene by transgenic mouse analysis and phylogenetic footprinting. Mol Cell Biol 25:3076-3086
31. Jenks BG 2009 Regulation of proopiomelanocortin gene expression: an overview of the signaling cascades, transcription factors, and responsive elements involved. Ann NY Acad Sci 1163:17-30
32. Maxwell MA, Muscat GE 2006 The NR4A subgroup: immediate early response genes with pleiotropic physiological roles. Nucl Recept Signal 4:e002
33. Gressens P, Muaku SM, Besse L, Nsegbe E, Gallego J, Delpech B, Gaultier C, Evrard P, Ketelslegers JM, Maiter D 1997 Maternal protein restriction early in rat pregnancy alters brain development in the progeny. Brain Res Dev Brain Res 103:21-35
34. Feoli AM, Leite MC, Tramontina AC, Tramontina F, Posser T, Rodrigues L, Swarowsky A, Quincozes-Santos A, Leal RB, Gottfried C, Perry ML, Gonçalves CA 2008 Developmental changes in content of glial marker proteins in rats exposed to protein malnutrition. Brain Res 1187:33-41
35. Plagemann A, Harder T, Rake A, Melchior K, Rohde W, Dörner G 2000 Hypothalamic nuclei are malformed in weanling offspring of low protein malnourished rat dams. J Nutr 130:2582-2589
36. Coupé B, Dutriez-Casteloot I, Breton C, Lefèvre F, Mairesse J, Dickes-Coopman A, Silhol M, Tapia-Arancibia L, Lesage J, Vieau D 2009 Perinatal undernutrition modifies cell proliferation and brain-derived neurotrophic factor levels during critical time-windows for hypothalamic and hippocampal development in the male rat. J Neuroendocrinol 21:40-48
37. Singer LK, Kuper J, Brogan RS, Smith MS, Grove KL 2000 Novel expression of hypothalamic neuropeptide Y during postnatal development in the rat. Neuroreport 11:1075-1080
38. Hahn TM, Breininger JF, Baskin DG, Schwartz MW 1998 Coexpression of Agrp and NPY in fasting-activated hypothalamic neurons. Nat Neurosci 1:271-272
39. Bouret SG, Gorski JN, Patterson CM, Chen S, Levin BE, Simerly RB 2008 Hypothalamic neural projections are permanently disrupted in diet-induced obese rats. Cell Metab 7:179-185
40. Desai M, Gayle D, Han G, Ross MG 2007 Programmed hyperphagia due to reduced anorexigenic mechanisms in intrauterine growth-restricted offspring. Reprod Sci 14:329-337
41. Valerio A, Ghisi V, Dossena M, Tonello C, Giordano A, Frontini A, Ferrario M, Pizzi M, Spano P, Carruba MO, Nisoli E 2006 Leptin increases axonal growth cone size in developing mouse cortical neurons by convergent signals inactivating glycogen synthase kinase-3β. J Biol Chem 281:12950-12958