Cytoprotective effect of Coreopsis tinctoria extracts and flavonoids on tBHP and cytokine-induced cell injury in pancreatic MIN6 cells

Journal of Ethnopharmacology

Volumn 139, Issue 2, 2012, Pages 485-492

  Dias, Teresa ^a   Liu, Bo ^b   Jones, Peter ^b   Houghton, Peter J ^b   Mota Filipe, Helder ^a   Paulo, Alexandra ^a  

^a RESEARCH INSTITUTE FOR MEDICINES IMED ULISBOA   (Portugal)

^b KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

Apoptosis; Beta cell; Cell viability; Coreopsis tinctoria; Marein; Superoxide radical anion

Indexed keywords

ANTIDIABETIC AGENT; CASPASE 3; CASPASE 7; COREOPSIS TINCTORIA EXTRACT; CYTOKINE; FALAVANOMAREIN; FLAVONOID; LUCIGENIN; MAREIN; PLANT EXTRACT; REACTIVE OXYGEN METABOLITE; TERT BUTYL HYDROPEROXIDE; UNCLASSIFIED DRUG;

ANIMAL CELL; ANTIDIABETIC ACTIVITY; APOPTOSIS; ARTICLE; CELL DAMAGE; CELL PROTECTION; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; COREOPSIS TINCTORIA; CYTOTOXICITY; DOSE RESPONSE; DRUG EFFECT; FLOWER; MEDICINAL PLANT; MOUSE; NONHUMAN; PANCREAS CELL;

ADENOSINE TRIPHOSPHATE; ANIMALS; APOPTOSIS; CASPASE 3; CASPASE 7; CELL LINE, TUMOR; CELL SURVIVAL; CHALCONES; COREOPSIS; CYTOKINES; CYTOPROTECTION; DOSE-RESPONSE RELATIONSHIP, DRUG; FLAVONOIDS; FLOWERS; INSULIN-SECRETING CELLS; INSULINOMA; MICE; OXIDANTS; OXIDATIVE STRESS; PANCREATIC NEOPLASMS; PLANT EXTRACTS; PLANTS, MEDICINAL; SUPEROXIDE DISMUTASE; SUPEROXIDES; TERT-BUTYLHYDROPEROXIDE; TIME FACTORS;

COREOPSIS TINCTORIA; RATTUS;

EID: 84856022525     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2011.11.038     Document Type: Article

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