Estrogens protect pancreatic β-cells from apoptosis and prevent insulin-deficient diabetes mellitus in mice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 103, Issue 24, 2006, Pages 9232-9237

  Le May, Cedric ^a   Chu, Khoi ^a   Hu, Min ^a   Ortega, Christina S ^a   Simpson, Evan R ^b   Korach, Kenneth S ^c   Tsai, Ming Jer ^a   Mauvais Jarvis, Franck ^a  

^a BAYLOR COLLEGE OF MEDICINE   (United States)

^b HUDSON INSTITUTE OF MEDICAL RESEARCH   (Australia)

^c NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

Author keywords

Estradiol; Oxidative stress

Indexed keywords

AROMATASE; ESTRADIOL; ESTROGEN; ESTROGEN RECEPTOR ALPHA; SEX HORMONE; STREPTOZOCIN; TAMOXIFEN;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CELL PROTECTION; CONTROLLED STUDY; DIABETES MELLITUS; DISEASE PREDISPOSITION; INSULIN DEFICIENCY; INSULIN SYNTHESIS; MOUSE; NONHUMAN; OXIDATIVE STRESS; PANCREAS ISLET; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL;

ANIMALS; APOPTOSIS; AROMATASE; CELL PROLIFERATION; CELL SURVIVAL; DIABETES MELLITUS, EXPERIMENTAL; DIABETES MELLITUS, TYPE 1; ESTRADIOL; ESTROGEN RECEPTOR ALPHA; FEMALE; HUMANS; INSULIN; INSULIN-SECRETING CELLS; MALE; MICE; MICE, KNOCKOUT; RANDOM ALLOCATION;

RODENTIA;

EID: 33745124662     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0602956103     Document Type: Article

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