-
1
-
-
0031423760
-
The nonobese diabetic mouse as a model of autoimmune diabetes: Immune disregulation gets the NOD
-
Delovitch, T., and Singh, B. 1997. The nonobese diabetic mouse as a model of autoimmune diabetes: immune disregulation gets the NOD. Immunity. 7:727-738.
-
(1997)
Immunity
, vol.7
, pp. 727-738
-
-
Delovitch, T.1
Singh, B.2
-
3
-
-
0029914999
-
Viruses, cytokines, antigens and autoimmunitv
-
Gianani, R., and Sarvetnick, N. 1996. Viruses, cytokines, antigens and autoimmunitv. Proc. Natl. Acad. Sci. USA. 93:2257-2259.
-
(1996)
Proc. Natl. Acad. Sci. USA
, vol.93
, pp. 2257-2259
-
-
Gianani, R.1
Sarvetnick, N.2
-
4
-
-
0342799404
-
Cytokines in the pathogenesis of type 1 diabetes
-
Rabinovitch, A. 1999. Cytokines in the pathogenesis of type 1 diabetes. Can. J. Diabetes Care. 23:40-51.
-
(1999)
Can. J. Diabetes Care
, vol.23
, pp. 40-51
-
-
Rabinovitch, A.1
-
5
-
-
0027468997
-
+ T-cells from diabetic versus prediabetic NOD.NON-thy-1a donors
-
+ T-cells from diabetic versus prediabetic NOD.NON-thy-1a donors. Diabetes. 42:44-55.
-
(1993)
Diabetes
, vol.42
, pp. 44-55
-
-
Christianson, S.1
Shultz, L.2
Leiter, E.3
-
6
-
-
0027367830
-
Major histocompatibility complex class 1 molecules are required for the generation of insulitis in non-obese diabetic mice
-
Katz, J., Benoist, C., and Mathis, D. 1993. Major histocompatibility complex class 1 molecules are required for the generation of insulitis in non-obese diabetic mice. Eur. J. Immunol. 23:3358-3360.
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 3358-3360
-
-
Katz, J.1
Benoist, C.2
Mathis, D.3
-
7
-
-
0028006398
-
β2-microglobulin-deficient NOD mice do not develop insulitis or diabetes
-
Wicker, L., et al. 1994. β2-microglobulin-deficient NOD mice do not develop insulitis or diabetes. Diabetes. 43:500-504.
-
(1994)
Diabetes
, vol.43
, pp. 500-504
-
-
Wicker, L.1
-
10
-
-
0031569582
-
Initiation of autoimmune diabetes in NOD/Lt mice is MHC class I-dependent
-
Serreze, D., et al. 1997. Initiation of autoimmune diabetes in NOD/Lt mice is MHC class I-dependent. J. Immunol. 157:3978-3986.
-
(1997)
J. Immunol.
, vol.157
, pp. 3978-3986
-
-
Serreze, D.1
-
11
-
-
0030022742
-
Transfer of diabetes in the NOD-scid mouse by CD4 T cell clones. Differential requirement for CD8 T cells
-
Peterson, J., and Haskins, K. 1996. Transfer of diabetes in the NOD-scid mouse by CD4 T cell clones. Differential requirement for CD8 T cells. Diabetes. 45:328-336.
-
(1996)
Diabetes
, vol.45
, pp. 328-336
-
-
Peterson, J.1
Haskins, K.2
-
13
-
-
0028990670
-
Lymphocyte-mediated cytotoxicity in vitro and in vivo: Mechanisms and significance
-
Kagi, D., Ledermann, B., Burki, K., Zinkernagel, R., and Hengartner, H. 1995. Lymphocyte-mediated cytotoxicity in vitro and in vivo: mechanisms and significance. Immunol. Rev. 146:95-115.
-
(1995)
Immunol. Rev.
, vol.146
, pp. 95-115
-
-
Kagi, D.1
Ledermann, B.2
Burki, K.3
Zinkernagel, R.4
Hengartner, H.5
-
14
-
-
1842289172
-
Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice
-
Kagi, D., et al. 1997 Reduced incidence and delayed onset of diabetes in perforin-deficient nonobese diabetic mice. J. Exp. Med. 186:989-997.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 989-997
-
-
Kagi, D.1
-
15
-
-
0030800122
-
Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice
-
Itoh, N., et al. 1997. Requirement of Fas for the development of autoimmune diabetes in nonobese diabetic mice. J. Exp. Med. 186:613-618.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 613-618
-
-
Itoh, N.1
-
16
-
-
0030890721
-
The role of Fas in autoimmune diabetes
-
Chervonsky, A., et al. 1997. The role of Fas in autoimmune diabetes. Cell. 89:17-24.
-
(1997)
Cell
, vol.89
, pp. 17-24
-
-
Chervonsky, A.1
-
17
-
-
0028990666
-
Mechanism and biological significance of CD4-mediated cytotoxicity
-
Hahn, S., Geri, R., and Erb, P. 1995. Mechanism and biological significance of CD4-mediated cytotoxicity. Immunol. Rev. 146:57-79.
-
(1995)
Immunol. Rev.
, vol.146
, pp. 57-79
-
-
Hahn, S.1
Geri, R.2
Erb, P.3
-
18
-
-
0030047314
-
+ CTL that utilizes a perforin rather than a Fas ligand dependent cytotoxic mechanism
-
+ CTL that utilizes a perforin rather than a Fas ligand dependent cytotoxic mechanism. J. Immunol. 156:153-159.
-
(1996)
J. Immunol.
, vol.156
, pp. 153-159
-
-
Williams, N.S.1
Engelhard, V.2
-
19
-
-
0030779118
-
A mechanism for the major histocompatibility complex-linked resistance to autoimmunity
-
Schmidt, D., Verdaguer, J., Averill, N., and Santamaria, P. 1997. A mechanism for the major histocompatibility complex-linked resistance to autoimmunity. J. Exp. Med. 186:1059-1075.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1059-1075
-
-
Schmidt, D.1
Verdaguer, J.2
Averill, N.3
Santamaria, P.4
-
20
-
-
0030724897
-
Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice
-
Verdaguer, J., et al. 1997. Spontaneous autoimmune diabetes in monoclonal T cell nonobese diabetic mice. J. Exp. Med. 186:1663-1676.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1663-1676
-
-
Verdaguer, J.1
-
21
-
-
0033560930
-
+ T lymphocytes in transgenic nonobese diabetic mice
-
+ T lymphocytes in transgenic nonobese diabetic mice. J. Clin. Invest. 103:1201-1209.
-
(1999)
J. Clin. Invest.
, vol.103
, pp. 1201-1209
-
-
Amrani, A.1
-
22
-
-
0025726216
-
A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
-
Nicoletti, I., Migliorati, G., Pagliacci, M., Grignani, F., and Riccardi, C. 1991. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. J. Immunol. Methods. 139:271-279.
-
(1991)
J. Immunol. Methods.
, vol.139
, pp. 271-279
-
-
Nicoletti, I.1
Migliorati, G.2
Pagliacci, M.3
Grignani, F.4
Riccardi, C.5
-
23
-
-
0030588572
-
+ T cells expressing identical endogenous TCRα chains
-
+ T cells expressing identical endogenous TCRα chains. J. Immunol. 157:4726-4735.
-
(1996)
J. Immunol.
, vol.157
, pp. 4726-4735
-
-
Verdaguer, J.1
-
25
-
-
0029856723
-
Mouse islet cell lysis mediated by interleukin-1-induced Fas
-
Yamada, K., Takane-Gyotoku, N., Ichikawa, F., Inada, C., and Nokada, K. 1996. Mouse islet cell lysis mediated by interleukin-1-induced Fas. Diabetologia. 39:1306-1312.
-
(1996)
Diabetologia
, vol.39
, pp. 1306-1312
-
-
Yamada, K.1
Takane-Gyotoku, N.2
Ichikawa, F.3
Inada, C.4
Nokada, K.5
-
26
-
-
0030731917
-
Nitric oxide primes pancreatic beta cells for Fas-mediated destruction in insulin-dependent diabetes mellitus
-
Stassi, G., et al. 1997. Nitric oxide primes pancreatic beta cells for Fas-mediated destruction in insulin-dependent diabetes mellitus. J. Exp. Med. 186:1193-1199.
-
(1997)
J. Exp. Med.
, vol.186
, pp. 1193-1199
-
-
Stassi, G.1
-
27
-
-
0030997703
-
IFN-γ increases the sensitivity of islets of Langerhans for inducible nitric oxide synthase expression induced by interleukin 1
-
Heitmeier, M., Scarim, A., and Corbett, J. 1997. IFN-γ increases the sensitivity of islets of Langerhans for inducible nitric oxide synthase expression induced by interleukin 1. J. Biol. Chem. 272:13697-13705.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 13697-13705
-
-
Heitmeier, M.1
Scarim, A.2
Corbett, J.3
-
28
-
-
0033178741
-
Evidence that beta cell death in the nonobese diabetic mouse is Fas independent
-
Thomas, H.E., Darwiche, R., Corbett, J.A., and Kay, T.W. 1999. Evidence that beta cell death in the nonobese diabetic mouse is Fas independent. J. Immunol. 163:1562-1569.
-
(1999)
J. Immunol.
, vol.163
, pp. 1562-1569
-
-
Thomas, H.E.1
Darwiche, R.2
Corbett, J.A.3
Kay, T.W.4
-
29
-
-
0033520295
-
Inflammatory cytokine regulation of Fas-mediated apoptosis in thyroid follicular cells
-
Bretz, J.D., Arscott, P.L., Myc, A., and Baker, J.R., Jr. 1999. Inflammatory cytokine regulation of Fas-mediated apoptosis in thyroid follicular cells. J. Biol. Chem. 274:25433-25438.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 25433-25438
-
-
Bretz, J.D.1
Arscott, P.L.2
Myc, A.3
Baker J.R., Jr.4
-
30
-
-
0028815078
-
Molecular pathways of CTL-mediated cytotoxicity
-
Clark, W., et al. 1995. Molecular pathways of CTL-mediated cytotoxicity. Immunol. Rev. 146:33-44.
-
(1995)
Immunol. Rev.
, vol.146
, pp. 33-44
-
-
Clark, W.1
-
31
-
-
0032506224
-
Mechanisms of beta cell death in diabetes: A minor role for CD95
-
Allison, J., and Strasser, A. 1998. Mechanisms of beta cell death in diabetes: a minor role for CD95. Proc. Natl. Acad. Sci. USA. 95:13818-13822.
-
(1998)
Proc. Natl. Acad. Sci. USA
, vol.95
, pp. 13818-13822
-
-
Allison, J.1
Strasser, A.2
-
33
-
-
0027170482
-
Antigen-presenting cells in adoptively transferred and spontaneous autoimmune diabetes
-
Lo, D., et al. 1993. Antigen-presenting cells in adoptively transferred and spontaneous autoimmune diabetes. Eur. J. Immunol. 23:1693-1698.
-
(1993)
Eur. J. Immunol.
, vol.23
, pp. 1693-1698
-
-
Lo, D.1
-
34
-
-
0025108875
-
Loss of pancreatic islet tolerance induced by beta cell-expression of interferon-gamma
-
Sarvetnick, N., et al. 1990. Loss of pancreatic islet tolerance induced by beta cell-expression of interferon-gamma. Nature. 346:844-847.
-
(1990)
Nature
, vol.346
, pp. 844-847
-
-
Sarvetnick, N.1
-
35
-
-
0032531099
-
INF-γ action on panreatic beta cells causes class I MHC upregulation but not diabetes
-
Thomas, H., Parker, J., Schreiber, R., and Kay, T. 1998. INF-γ action on panreatic beta cells causes class I MHC upregulation but not diabetes. J. Clin. Invest. 102:1249-1257.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 1249-1257
-
-
Thomas, H.1
Parker, J.2
Schreiber, R.3
Kay, T.4
-
36
-
-
0027337691
-
Induction of type I diabetes by interferon-alpha in transgenic mice
-
Stewart, T., et al. 1993. Induction of type I diabetes by interferon-alpha in transgenic mice. Science. 260:1942-1946.
-
(1993)
Science
, vol.260
, pp. 1942-1946
-
-
Stewart, T.1
-
37
-
-
0026474808
-
Expression of a tumor necrosis factor-α transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes
-
Higuchi, Y., et al. 1992. Expression of a tumor necrosis factor-α transgene in murine pancreatic beta cells results in severe and permanent insulitis without evolution towards diabetes. J. Exp. Med. 176:1719-1726.
-
(1992)
J. Exp. Med.
, vol.176
, pp. 1719-1726
-
-
Higuchi, Y.1
-
38
-
-
0026443846
-
Insulitis in transgenic mice expressing tumor necrosis factor beta (lymphotoxin) in the pancreas
-
Picarella, D., Kratz, A., Li, C., Ruddle, N., and Flavell, R. 1992. Insulitis in transgenic mice expressing tumor necrosis factor beta (lymphotoxin) in the pancreas. Proc. Natl. Acad. Sci. USA. 89:10036-10041.
-
(1992)
Proc. Natl. Acad. Sci. USA
, vol.89
, pp. 10036-10041
-
-
Picarella, D.1
Kratz, A.2
Li, C.3
Ruddle, N.4
Flavell, R.5
-
39
-
-
0031252369
-
Fas and Fas ligand enhance the pathogenesis of experimental allergic encephalomyelitis, but are not essential for immune privilege in the central nervous system
-
Sabelko, K., Kelly, K., Nahm, M., Cross, A., and Russell, J. 1997. Fas and Fas ligand enhance the pathogenesis of experimental allergic encephalomyelitis, but are not essential for immune privilege in the central nervous system. J. Immunol. 159:3096-3099.
-
(1997)
J. Immunol.
, vol.159
, pp. 3096-3099
-
-
Sabelko, K.1
Kelly, K.2
Nahm, M.3
Cross, A.4
Russell, J.5
-
40
-
-
0031253737
-
Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis
-
Waldner, H., Sobel, R., Howard, E., and Kuchroo, V. 1997. Fas- and FasL-deficient mice are resistant to induction of autoimmune encephalomyelitis. J. Immunol. 159:3100-3103.
-
(1997)
J. Immunol.
, vol.159
, pp. 3100-3103
-
-
Waldner, H.1
Sobel, R.2
Howard, E.3
Kuchroo, V.4
-
41
-
-
0033556272
-
The role of the antigen-presenting cell in Fas-mediated direct and bystander killing: Potential in vivo function of Fas in experimental allergic encephalomyelitis
-
Thilenius, A., Sabelko-Downes, K., and Russell, J. 1999. The role of the antigen-presenting cell in Fas-mediated direct and bystander killing: potential in vivo function of Fas in experimental allergic encephalomyelitis. J. Immunol. 162:643-650.
-
(1999)
J. Immunol.
, vol.162
, pp. 643-650
-
-
Thilenius, A.1
Sabelko-Downes, K.2
Russell, J.3
-
43
-
-
0033579877
-
The role of macrophages in T cell-mediated autoimmune diabetes in nonobese diabetic mice
-
Jun, H., Yoon, C., Zbytnuik, L., Rooijen, N.V., and Yoon, J. 1999. The role of macrophages in T cell-mediated autoimmune diabetes in nonobese diabetic mice. J. Exp. Med. 189:347-358.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 347-358
-
-
Jun, H.1
Yoon, C.2
Zbytnuik, L.3
Rooijen, N.V.4
Yoon, J.5
-
47
-
-
0031465966
-
CD95 and CD95-ligand expression in endocrine pancreas of NOD, NOR and BALB/c mice
-
Signore, A., et al. 1997. CD95 and CD95-ligand expression in endocrine pancreas of NOD, NOR and BALB/c mice. Diabetologia. 40:1476-1479.
-
(1997)
Diabetologia
, vol.40
, pp. 1476-1479
-
-
Signore, A.1
-
48
-
-
0033526068
-
In autoimmune diabetes the transition from benign to pernicious insulitis requires an inslet cell response to tumor necrosis factor α
-
Pakala, S., Chivetta, M., Kelly, C., and Katz, J. 1999. In autoimmune diabetes the transition from benign to pernicious insulitis requires an inslet cell response to tumor necrosis factor α. J. Exp. Med. 189:1053-1062.
-
(1999)
J. Exp. Med.
, vol.189
, pp. 1053-1062
-
-
Pakala, S.1
Chivetta, M.2
Kelly, C.3
Katz, J.4
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