S-allylmercapto-N-acetylcysteine up-regulates cellular glutathione and protects vascular endothelial cells from oxidative stress

Free Radical Biology and Medicine

Volumn 50, Issue 9, 2011, Pages 1131-1139

  Izigov, Nira ^a   Farzam, Nahid ^a   Savion, Naphtali ^a  

^a TEL AVIV UNIVERSITY   (Israel)

Author keywords

Cytotoxicity; Endothelial cells; Free radicals; Gene expression; Glutamate cysteine ligase modifier subunit; Glutathione; N acetylcysteine; Nuclear factor erythroid 2 related factor 2; Reactive oxygen species; S allylmercapto N acetylcysteine

Indexed keywords

ACETYLCYSTEINE; ACETYLCYSTEINE DERIVATIVE; ALLICIN; CYSTEINE; GLUTAMATE CYSTEINE LIGASE; GLUTATHIONE; HEME OXYGENASE 1; INTERCELLULAR ADHESION MOLECULE 1; PROTEIN; S ALLYL MERCAPTAN; S ALLYLMERCAPTO N ACETYLCYSTEINE; S ALLYLMERCAPTOCYSTEINE; TERT BUTYL ALCOHOL; THIOL DERIVATIVE; TRANSCRIPTION FACTOR NRF2; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG; VASCULAR CELL ADHESION MOLECULE 1; XCT PROTEIN;

ANIMAL CELL; ANIMAL CELL CULTURE; ARTICLE; CELL NUCLEUS; CONTROLLED STUDY; COW; DRUG CYTOTOXICITY; DRUG EXPOSURE; DRUG SYNTHESIS; HYDROPHOBICITY; MICROVASCULAR ENDOTHELIAL CELL; NONHUMAN; OXIDATIVE STRESS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; UPREGULATION;

ACETYLCYSTEINE; ANIMALS; ANTIOXIDANTS; AORTA; CATTLE; CELLS, CULTURED; CYSTEINE; CYTOPROTECTION; ENDOTHELIAL CELLS; GLUTATHIONE; METABOLIC DETOXICATION, PHASE II; NF-E2-RELATED FACTOR 2; OXIDATIVE STRESS; SULFINIC ACIDS; TERT-BUTYLHYDROPEROXIDE; TRANSCRIPTIONAL ACTIVATION; UP-REGULATION;

EID: 79953238648     PISSN: 08915849     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2011.01.028     Document Type: Article

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