-
2
-
-
0037135626
-
The Ceramide-centric universe of lipid-mediated cell regulation: Stress encounters of the lipid kind
-
Hannun YA, Obeid LM. The Ceramide-centric universe of lipid-mediated cell regulation: stress encounters of the lipid kind. J Biol Chem 2002; 277: 25847-50.
-
(2002)
J Biol Chem
, vol.277
, pp. 25847-25850
-
-
Hannun, Y.A.1
Obeid, L.M.2
-
3
-
-
3543114272
-
Biologically active sphingolipids in cancer pathogenesis and treatment
-
Ogretmen B, Hannun YA, Biologically active sphingolipids in cancer pathogenesis and treatment. Nat Rev Cancer 2004; 4: 604-16.
-
(2004)
Nat Rev Cancer
, vol.4
, pp. 604-616
-
-
Ogretmen, B.1
Hannun, Y.A.2
-
4
-
-
38549152194
-
Principles of bioactive lipid signalling: Lessons from sphingolipids
-
Hannun YA, Obeid LM. Principles of bioactive lipid signalling: lessons from sphingolipids. Nat Rev Mol Cell Biol 2008; 9: 139-50.
-
(2008)
Nat Rev Mol Cell Biol
, vol.9
, pp. 139-150
-
-
Hannun, Y.A.1
Obeid, L.M.2
-
5
-
-
19444377889
-
Molecular associations and surface-active properties of short-and long-N-acyl chain ceramides
-
Sot J, Goni FM, Alonso A. Molecular associations and surface-active properties of short-and long-N-acyl chain ceramides. Biochim Biophys Acta 2005; 1711: 12-9.
-
(2005)
Biochim Biophys Acta
, vol.1711
, pp. 12-19
-
-
Sot, J.1
Goni, F.M.2
Alonso, A.3
-
6
-
-
20444363393
-
The ins and outs of sphingolipid synthesis
-
Futerman AH, Riezman H. The ins and outs of sphingolipid synthesis. Trends Cell Biol 2005; 15: 312-8.
-
(2005)
Trends Cell Biol
, vol.15
, pp. 312-318
-
-
Futerman, A.H.1
Riezman, H.2
-
7
-
-
21844477032
-
Rapid transbilayer movement of ceramides in phospholipid vesicles and in human erythrocytes
-
López-Montero I, Rodriguez N, Cribier S, Pohl A, Vélez M, Devaux PF. Rapid transbilayer movement of ceramides in phospholipid vesicles and in human erythrocytes. J Biol Chem 2005; 280: 25811-9.
-
(2005)
J Biol Chem
, vol.280
, pp. 25811-25819
-
-
López-Montero, I.1
Rodriguez, N.2
Cribier, S.3
Pohl, A.4
Vélez, M.5
Devaux, P.F.6
-
8
-
-
77951931341
-
Transbilayer (flip-flop) lipid motion and lipid scrambling in membranes
-
Contreras FX, Sánchez-Magraner L, Alonso A, Goñi FM. Transbilayer (flip-flop) lipid motion and lipid scrambling in membranes. FEBS Lett 2010; 584: 1779-86.
-
(2010)
FEBS Lett
, vol.584
, pp. 1779-1786
-
-
Contreras, F.X.1
Sánchez-Magraner, L.2
Alonso, A.3
Goñi, F.M.4
-
9
-
-
20444402239
-
Molecular mechanisms and regulation of ceramide transport
-
Perry RJ, Ridgway ND. Molecular mechanisms and regulation of ceramide transport. Biochim Biophys Acta 2005; 1734: 220-34.
-
(2005)
Biochim Biophys Acta
, vol.1734
, pp. 220-234
-
-
Perry, R.J.1
Ridgway, N.D.2
-
10
-
-
0347611095
-
Molecular machinery for non-vesicular trafficking of ceramide
-
Hanada K, Kumagai K, Yasuda S, Miura Y, Kawano M, Fukasawa M, Nishijima M. Molecular machinery for non-vesicular trafficking of ceramide. Nature 2003; 426: 803-9.
-
(2003)
Nature
, vol.426
, pp. 803-809
-
-
Hanada, K.1
Kumagai, K.2
Yasuda, S.3
Miura, Y.4
Kawano, M.5
Fukasawa, M.6
Nishijima, M.7
-
11
-
-
0030844101
-
Conversion of dihydroceramide to ceramide occurs at the cytosolic face of the endoplasmic reticulum
-
Michel C, van Echten-Deckert G. Conversion of dihydroceramide to ceramide occurs at the cytosolic face of the endoplasmic reticulum. FEBS Lett 1997; 416: 153-5.
-
(1997)
FEBS Lett
, vol.416
, pp. 153-155
-
-
Michel, C.1
van Echten-Deckert, G.2
-
12
-
-
0027413499
-
The long-chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endo-plasmic reticulum in rat liver
-
Hirschberg K, Rodger J, Futerman AH. The long-chain sphingoid base of sphingolipids is acylated at the cytosolic surface of the endo-plasmic reticulum in rat liver. Biochem J 1993; 290: 751-7.
-
(1993)
Biochem J
, vol.290
, pp. 751-757
-
-
Hirschberg, K.1
Rodger, J.2
Futerman, A.H.3
-
13
-
-
0026712872
-
Subcellular localization and membrane topology of serine palmitoyltransferase, 3-dehydrosphinganine reductase, and sphin-ganine N-acyltransferase in mouse liver
-
Mandon EC, Ehses I, Rother J, van Echten G, Sandhoff K. Subcellular localization and membrane topology of serine palmitoyltransferase, 3-dehydrosphinganine reductase, and sphin-ganine N-acyltransferase in mouse liver. J Biol Chem 1992; 267: 11144-8.
-
(1992)
J Biol Chem
, vol.267
, pp. 11144-11148
-
-
Mandon, E.C.1
Ehses, I.2
Rother, J.3
van Echten, G.4
Sandhoff, K.5
-
14
-
-
0037135536
-
De novo sphingolipid biosynthesis: A necessary, but dangerous, pathway
-
Merrill AH. De novo sphingolipid biosynthesis: a necessary, but dangerous, pathway. J Biol Chem 2002; 277: 25843-6.
-
(2002)
J Biol Chem
, vol.277
, pp. 25843-25846
-
-
Merrill, A.H.1
-
15
-
-
0037135608
-
Combinatorial ganglioside biosynthesis
-
Kolter T, Proia RL, Sandhoff K. Combinatorial ganglioside biosynthesis. J Biol Chem 2002; 277: 25859-62.
-
(2002)
J Biol Chem
, vol.277
, pp. 25859-25862
-
-
Kolter, T.1
Proia, R.L.2
Sandhoff, K.3
-
16
-
-
0025323167
-
Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus
-
Futerman AH, Stieger B, Hubbard AL, Pagano RE. Sphingomyelin synthesis in rat liver occurs predominantly at the cis and medial cisternae of the Golgi apparatus. J Biol Che, 1990; 265: 8650-7.
-
(1990)
J Biol Che
, vol.265
, pp. 8650-8657
-
-
Futerman, A.H.1
Stieger, B.2
Hubbard, A.L.3
Pagano, R.E.4
-
17
-
-
23944483995
-
Mammalian Lass6 and its related family members regulate synthesis of specific ceramides
-
Mizutani Y, Kihara A, Igarashi Y. Mammalian Lass6 and its related family members regulate synthesis of specific ceramides. Biochem J 2005; 390: 263-71.
-
(2005)
Biochem J
, vol.390
, pp. 263-271
-
-
Mizutani, Y.1
Kihara, A.2
Igarashi, Y.3
-
18
-
-
33748747214
-
LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity
-
Mizutani Y, Kihara A, Igarashi Y. LASS3 (longevity assurance homologue 3) is a mainly testis-specific (dihydro)ceramide synthase with relatively broad substrate specificity. Bio-chem J 2006; 398: 531-8.
-
(2006)
Bio-chem J
, vol.398
, pp. 531-538
-
-
Mizutani, Y.1
Kihara, A.2
Igarashi, Y.3
-
19
-
-
41949140023
-
Characterization of ceramide synthase 2: Tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate
-
Laviad EL, Albee L, Pankova-Kholmyansky I, Epstein S, Park H, Merrill AH Jr, Futerman AH. Characterization of ceramide synthase 2: tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate. J Biol Chem 2008; 283: 5677-84.
-
(2008)
J Biol Chem
, vol.283
, pp. 5677-5684
-
-
Laviad, E.L.1
Albee, L.2
Pankova-Kholmyansky, I.3
Epstein, S.4
Park, H.5
Merrill Jr., A.H.6
Futerman, A.H.7
-
20
-
-
26644468150
-
LASS5 is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl-CoA as acyl donor
-
Lahiri S, Futerman AH. LASS5 is a bona fide dihydroceramide synthase that selectively utilizes palmitoyl-CoA as acyl donor. J Biol Chem 2005; 280: 33735-8.
-
(2005)
J Biol Chem
, vol.280
, pp. 33735-33738
-
-
Lahiri, S.1
Futerman, A.H.2
-
21
-
-
33845952389
-
Necessary role for the Lag1p motif in (dihydro)ceramide synthase activity
-
Spassieva S, Seo JG, Jiang JC, Bielawski J, Alvarez-Vasquez F, Jazwinski SM, Hannun YA, Obeid LM. Necessary role for the Lag1p motif in (dihydro)ceramide synthase activity. J Biol Chem 2006; 281: 33931-8.
-
(2006)
J Biol Chem
, vol.281
, pp. 33931-33938
-
-
Spassieva, S.1
Seo, J.G.2
Jiang, J.C.3
Bielawski, J.4
Alvarez-Vasquez, F.5
Jazwinski, S.M.6
Hannun, Y.A.7
Obeid, L.M.8
-
22
-
-
67649398798
-
Ceramide synthase 1 is regulated by protea-somal mediated turnover
-
Sridevi P, Alexander H, Laviad EL, Pewzner-Jung Y, Hannink M, Futerman AH, Alexander S. Ceramide synthase 1 is regulated by protea-somal mediated turnover. Biochim Biophys Acta 2009; 1793: 1218-27.
-
(2009)
Biochim Biophys Acta
, vol.1793
, pp. 1218-1227
-
-
Sridevi, P.1
Alexander, H.2
Laviad, E.L.3
Pewzner-Jung, Y.4
Hannink, M.5
Futerman, A.H.6
Alexander, S.7
-
23
-
-
0037174116
-
Do longevity assurance genes containing Hox domains regulate cell development via ceramide synthesis?
-
Venkataraman K, Futerman AH. Do longevity assurance genes containing Hox domains regulate cell development via ceramide synthesis? FEBS Lett 2002; 528: 3-4.
-
(2002)
FEBS Lett
, vol.528
, pp. 3-4
-
-
Venkataraman, K.1
Futerman, A.H.2
-
24
-
-
33845708225
-
Ceramide/sphingosine/sphingosine 1-phosphate metabolism on the cell surface and in the extracellular space
-
Tani M, Ito M, Igarashi Y. Ceramide/sphingosine/sphingosine 1-phosphate metabolism on the cell surface and in the extracellular space. Cell Signal 2007; 19: 229-37.
-
(2007)
Cell Signal
, vol.19
, pp. 229-237
-
-
Tani, M.1
Ito, M.2
Igarashi, Y.3
-
25
-
-
27744558995
-
Involvement of neutral ceramidase in ceramide metabolism at the plasma membrane and in extracellular milieu
-
Tani M, Igarashi Y, Ito M. Involvement of neutral ceramidase in ceramide metabolism at the plasma membrane and in extracellular milieu. J Biol Chem 2005; 280: 36592-600.
-
(2005)
J Biol Chem
, vol.280
, pp. 36592-36600
-
-
Tani, M.1
Igarashi, Y.2
Ito, M.3
-
27
-
-
0024478236
-
A new Zn2+-stimulated sphingomyelinase in fetal bovine serum
-
Spence MW, Byers DM, Palmer FB, Cook HW. A new Zn2+-stimulated sphingomyelinase in fetal bovine serum. J Biol Chem 1989; 264: 5358-63.
-
(1989)
J Biol Chem
, vol.264
, pp. 5358-5363
-
-
Spence, M.W.1
Byers, D.M.2
Palmer, F.B.3
Cook, H.W.4
-
28
-
-
79954509850
-
The neutral sphingomyelinase family: Identifying biochemical connections
-
Clarke CJ, Wu BX, Hannun YA. The neutral sphingomyelinase family: identifying biochemical connections. Adv Enzyme Regul 2011; 51: 51-8.
-
(2011)
Adv Enzyme Regul
, vol.51
, pp. 51-58
-
-
Clarke, C.J.1
Wu, B.X.2
Hannun, Y.A.3
-
29
-
-
0034102425
-
Characterization and subcellular localization of mur-ine and human magnesium-dependent neutral sphingomyelinase
-
Tomiuk S, Zumbansen M, Stoffel W. Characterization and subcellular localization of mur-ine and human magnesium-dependent neutral sphingomyelinase. J Biol Chem 2000; 275: 5710-7.
-
(2000)
J Biol Chem
, vol.275
, pp. 5710-5717
-
-
Tomiuk, S.1
Zumbansen, M.2
Stoffel, W.3
-
30
-
-
33749009744
-
The extended family of neutral sphingomyelinases
-
Clarke CJ, Snook CF, Tani M, Matmati N, Marchesini N, Hannun YA. The extended family of neutral sphingomyelinases. Biochemistry 2006; 45: 11247-56.
-
(2006)
Biochemistry
, vol.45
, pp. 11247-11256
-
-
Clarke, C.J.1
Snook, C.F.2
Tani, M.3
Matmati, N.4
Marchesini, N.5
Hannun, Y.A.6
-
31
-
-
2942532249
-
Role for mammalian neutral sphingomyelinase 2 in confluence-induced growth arrest of MCF7 cells
-
Marchesini N, Osta W, Bielawski J, Luberto C, Obeid LM, Hannun YA. Role for mammalian neutral sphingomyelinase 2 in confluence-induced growth arrest of MCF7 cells. J Biol Chem 2004; 279: 25101-11.
-
(2004)
J Biol Chem
, vol.279
, pp. 25101-25111
-
-
Marchesini, N.1
Osta, W.2
Bielawski, J.3
Luberto, C.4
Obeid, L.M.5
Hannun, Y.A.6
-
32
-
-
77951889353
-
Sphingomye-lin metabolism at the plasma membrane: Implications for bioactive sphingolipids
-
Milhas D, Clarke CJ, Hannun YA. Sphingomye-lin metabolism at the plasma membrane: implications for bioactive sphingolipids. FEBS Lett 2010; 584: 1887-94.
-
(2010)
FEBS Lett
, vol.584
, pp. 1887-1894
-
-
Milhas, D.1
Clarke, C.J.2
Hannun, Y.A.3
-
33
-
-
77952937382
-
Identification and characterization of murine mitochondria-associated neutral sphingomyelinase (MA-nSMase), the mammalian sphingomyelin phosphodiesterase 5
-
Wu BX, Rajagopalan V, Roddy PL, Clarke CJ, Hannun YA. Identification and characterization of murine mitochondria-associated neutral sphingomyelinase (MA-nSMase), the mammalian sphingomyelin phosphodiesterase 5. J Biol Chem 2010; 285: 17993-8002.
-
(2010)
J Biol Chem
, vol.285
, pp. 17993-18002
-
-
Wu, B.X.1
Rajagopalan, V.2
Roddy, P.L.3
Clarke, C.J.4
Hannun, Y.A.5
-
34
-
-
30844463225
-
Absorption and lipopro-tein transport of sphingomyelin
-
Nilsson A, Duan RD. Absorption and lipopro-tein transport of sphingomyelin. J Lipid Res 2006; 47: 154-71.
-
(2006)
J Lipid Res
, vol.47
, pp. 154-171
-
-
Nilsson, A.1
Duan, R.D.2
-
35
-
-
42249105215
-
The sphingolipid salvage pathway in ceramide metabolism and signaling
-
Kitatani K, Idkowiak-Baldys J, Hannun YA. The sphingolipid salvage pathway in ceramide metabolism and signaling. Cell Signal 2008; 20: 1010-8.
-
(2008)
Cell Signal
, vol.20
, pp. 1010-1018
-
-
Kitatani, K.1
Idkowiak-Baldys, J.2
Hannun, Y.A.3
-
36
-
-
0032502854
-
Natural ceramide is unable to escape the lysosome, in contrast to a fluorescent analogue
-
Chatelut M, Leruth M, Harzer K, Dagan A, Marchesini S, Gatt S, Salvayre R, Courtoy P, Levade T. Natural ceramide is unable to escape the lysosome, in contrast to a fluorescent analogue. FEBS Lett 1998; 426: 102-6.
-
(1998)
FEBS Lett
, vol.426
, pp. 102-106
-
-
Chatelut, M.1
Leruth, M.2
Harzer, K.3
Dagan, A.4
Marchesini, S.5
Gatt, S.6
Salvayre, R.7
Courtoy, P.8
Levade, T.9
-
37
-
-
0035910473
-
Occurrence of ceramides and neutral glycolipids with unusual long-chain base composition in purified rat liver mitochondria
-
Ardail D, Popa I, Alcantara K, Pons A, Zanetta JP, Louisot P, Thomas L, Portoukalian J. Occurrence of ceramides and neutral glycolipids with unusual long-chain base composition in purified rat liver mitochondria. FEBS Lett 2001; 488: 160-4.
-
(2001)
FEBS Lett
, vol.488
, pp. 160-164
-
-
Ardail, D.1
Popa, I.2
Alcantara, K.3
Pons, A.4
Zanetta, J.P.5
Louisot, P.6
Thomas, L.7
Portoukalian, J.8
-
38
-
-
0242690342
-
Quantitation and molecular species determination of diacylglycerols, phosphatidylcholines, ceramides, and sphin-gomyelins with gas chromatography
-
Tserng KY, Griffin R. Quantitation and molecular species determination of diacylglycerols, phosphatidylcholines, ceramides, and sphin-gomyelins with gas chromatography. Anal Biochem 2003; 323: 84-93.
-
(2003)
Anal Biochem
, vol.323
, pp. 84-93
-
-
Tserng, K.Y.1
Griffin, R.2
-
39
-
-
0035199418
-
Selective hydrolysis of a mitochondrial pool of sphingomyelin induces apoptosis
-
Birbes H, El Bawab S, Hannun YA, Obeid LM. Selective hydrolysis of a mitochondrial pool of sphingomyelin induces apoptosis. Faseb J 2001; 15: 2669-79.
-
(2001)
Faseb J
, vol.15
, pp. 2669-2679
-
-
Birbes, H.1
El-Bawab, S.2
Hannun, Y.A.3
Obeid, L.M.4
-
40
-
-
53349098893
-
Ceramide biogenesis is required for radiation-induced apoptosis in the germ line of C. elegans
-
Deng X, Yin X, Allan R, Lu DD, Maurer CW, Haimovitz-Friedman A, Fuks Z, Shaham S, Kolesnick R. Ceramide biogenesis is required for radiation-induced apoptosis in the germ line of C. elegans. Science 2008; 322: 110-5.
-
(2008)
Science
, vol.322
, pp. 110-115
-
-
Deng, X.1
Yin, X.2
Allan, R.3
Lu, D.D.4
Maurer, C.W.5
Haimovitz-Friedman, A.6
Fuks, Z.7
Shaham, S.8
Kolesnick, R.9
-
41
-
-
2442711625
-
Mitochondrial ceramide increases in UV-irradiated HeLa cells and is mainly derived from hydrolysis of sphingomyelin
-
Dai Q, Liu J, Chen J, Durrant D, McIntyre TM, Lee RM. Mitochondrial ceramide increases in UV-irradiated HeLa cells and is mainly derived from hydrolysis of sphingomyelin. Oncogene 2004; 23: 3650-8.
-
(2004)
Oncogene
, vol.23
, pp. 3650-3658
-
-
Dai, Q.1
Liu, J.2
Chen, J.3
Durrant, D.4
McIntyre, T.M.5
Lee, R.M.6
-
42
-
-
67749120148
-
A novel mi-tochondrial sphingomyelinase in zebrafish cells
-
Yabu T, Shimuzu A, Yamashita M. A novel mi-tochondrial sphingomyelinase in zebrafish cells. J Biol Chem 2009; 284: 20349-63.
-
(2009)
J Biol Chem
, vol.284
, pp. 20349-20363
-
-
Yabu, T.1
Shimuzu, A.2
Yamashita, M.3
-
43
-
-
77956813485
-
Subcellular organelle lipi-domics in TLR-4-activated macrophages
-
Andreyev AY, Fahy E, Guan Z, Kelly S, Li X, McDonald JG, Milne S, Myers D, Park H, Ryan A, Thompson BM, Wang E, Zhao Y, Brown HA, Merrill AH, Raetz CR, Russell DW, Subrama-niam S, Dennis EA. Subcellular organelle lipi-domics in TLR-4-activated macrophages. J Lipid Res 2010; 51: 2785-97.
-
(2010)
J Lipid Res
, vol.51
, pp. 2785-2797
-
-
Andreyev, A.Y.1
Fahy, E.2
Guan, Z.3
Kelly, S.4
Li, X.5
McDonald, J.G.6
Milne, S.7
Myers, D.8
Park, H.9
Ryan, A.10
Thompson, B.M.11
Wang, E.12
Zhao, Y.13
Brown, H.A.14
Merrill, A.H.15
Raetz, C.R.16
Russell, D.W.17
Subrama-Niam, S.18
Dennis, E.A.19
-
44
-
-
77955055151
-
Characteristics of the rat cardiac sphingolipid pool in two mitochon-drial subpopulations
-
Monette JS, Gómez LA, Moreau RF, Bemer BA, Taylor AW, Hagen TM. Characteristics of the rat cardiac sphingolipid pool in two mitochon-drial subpopulations. Biochem Biophys Res Commun 2010; 398: 272-7.
-
(2010)
Biochem Biophys Res Commun
, vol.398
, pp. 272-277
-
-
Monette, J.S.1
Gómez, L.A.2
Moreau, R.F.3
Bemer, B.A.4
Taylor, A.W.5
Hagen, T.M.6
-
45
-
-
0014961287
-
Specificity in ceramide biosynthesis from long chain bases and various fatty acyl coenzyme A's by brain micro-somes
-
Morell P, Radin NS. Specificity in ceramide biosynthesis from long chain bases and various fatty acyl coenzyme A's by brain micro-somes. J Biol Chem 1970; 245: 342-50.
-
(1970)
J Biol Chem
, vol.245
, pp. 342-350
-
-
Morell, P.1
Radin, N.S.2
-
46
-
-
0015411521
-
Enzymatic formation of hydroxy ceramides and comparison with enzymes forming nonhydroxy ceramides
-
Ullman MD, Radin NS. Enzymatic formation of hydroxy ceramides and comparison with enzymes forming nonhydroxy ceramides. Arch Biochem Biophys 1972; 152: 767-77.
-
(1972)
Arch Biochem Biophys
, vol.152
, pp. 767-777
-
-
Ullman, M.D.1
Radin, N.S.2
-
47
-
-
0028871364
-
Fatty acyl-Co A: Sphingosine acyltransferase in bovine brain mitochondria: Its solubilization and reconstitution onto the membrane lipid liposomes
-
Shimeno H, Soeda S, Yasukouchi M, Okamura N, Nagamatsu A. Fatty acyl-Co A: sphingosine acyltransferase in bovine brain mitochondria: its solubilization and reconstitution onto the membrane lipid liposomes. Biol Pharm Bull 1995; 18: 1335-9.
-
(1995)
Biol Pharm Bull
, vol.18
, pp. 1335-1339
-
-
Shimeno, H.1
Soeda, S.2
Yasukouchi, M.3
Okamura, N.4
Nagamatsu, A.5
-
48
-
-
0031800791
-
Partial purification and characterization of sphingosine N-acyltransferase (ceramide synthase) from bovine liver mitochondrion-rich fraction
-
Shimeno H, Soeda S, Sakamoto M, Kouchi T, Kowakame T, Kihara T. Partial purification and characterization of sphingosine N-acyltransferase (ceramide synthase) from bovine liver mitochondrion-rich fraction. Lipids 1998; 33: 601-5.
-
(1998)
Lipids
, vol.33
, pp. 601-605
-
-
Shimeno, H.1
Soeda, S.2
Sakamoto, M.3
Kouchi, T.4
Kowakame, T.5
Kihara, T.6
-
49
-
-
4544261024
-
Subcellular compartmen-talization of ceramide metabolism: MAM (mitochondria-associated membrane) and/or mitochondria?
-
Bionda C, Portoukalian J, Schmitt D, Rodriguez -Lafrasse C, Ardail D. Subcellular compartmen-talization of ceramide metabolism: MAM (mitochondria-associated membrane) and/or mitochondria? Biochem J 2004; 382: 527-33.
-
(2004)
Biochem J
, vol.382
, pp. 527-533
-
-
Bionda, C.1
Portoukalian, J.2
Schmitt, D.3
Rodriguez-Lafrasse, C.4
Ardail, D.5
-
50
-
-
34548478108
-
JNK3 signaling pathway activates ceramide synthase leading to mitochondrial dysfunction
-
Yu J, Novgorodov SA, Chudakova D, Zhu H, Bielawska A, Bielawski J, Obeid LM, Kindy MS, Gudz TI. JNK3 signaling pathway activates ceramide synthase leading to mitochondrial dysfunction. J Biol Chem 2007; 282: 25940-9.
-
(2007)
J Biol Chem
, vol.282
, pp. 25940-25949
-
-
Yu, J.1
Novgorodov, S.A.2
Chudakova, D.3
Zhu, H.4
Bielawska, A.5
Bielawski, J.6
Obeid, L.M.7
Kindy, M.S.8
Gudz, T.I.9
-
51
-
-
79953018812
-
Developmentally regulated ceramide synthase 6 increases mitochondrial Ca2+ loading capacity and promotes apoptosis
-
Novgorodov SA, Chudakova DA, Wheeler BW, Bielawski J, Kindy MS, Obeid LM, Gudz TI. Developmentally regulated ceramide synthase 6 increases mitochondrial Ca2+ loading capacity and promotes apoptosis. J Biol Chem 2011; 286: 4644-58.
-
(2011)
J Biol Chem
, vol.286
, pp. 4644-4658
-
-
Novgorodov, S.A.1
Chudakova, D.A.2
Wheeler, B.W.3
Bielawski, J.4
Kindy, M.S.5
Obeid, L.M.6
Gudz, T.I.7
-
52
-
-
33845320488
-
Intracellular trafficking of sphin-golipids: Relationship to biosynthesis
-
Futerman AH. Intracellular trafficking of sphin-golipids: relationship to biosynthesis. Biochim Biophys Acta 2006; 1758: 1885-92.
-
(2006)
Biochim Biophys Acta
, vol.1758
, pp. 1885-1892
-
-
Futerman, A.H.1
-
53
-
-
77953728877
-
Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells
-
Mesicek J, Lee H, Feldman T, Jiang X, Skobeleva A, Berdyshev EV, Haimovitz-Friedman A, Fuks Z, Kolesnick R. Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells. Cell Signal 2010; 22: 1300-7.
-
(2010)
Cell Signal
, vol.22
, pp. 1300-1307
-
-
Mesicek, J.1
Lee, H.2
Feldman, T.3
Jiang, X.4
Skobeleva, A.5
Berdyshev, E.V.6
Haimovitz-Friedman, A.7
Fuks, Z.8
Kolesnick, R.9
-
54
-
-
1642564715
-
Activation and localization of inositol phos-phosphingolipid phospholipase C, Isc1p, to the mitochondria during growth of Saccharo-myces cerevisiae
-
Vaena de Avalos S, Okamoto Y, Hannun YA., Activation and localization of inositol phos-phosphingolipid phospholipase C, Isc1p, to the mitochondria during growth of Saccharo-myces cerevisiae. J Biol Chem 2004; 279: 11537-45.
-
(2004)
J Biol Chem
, vol.279
, pp. 11537-11545
-
-
de Avalos, S.V.1
Okamoto, Y.2
Hannun, Y.A.3
-
55
-
-
36048969412
-
Isc1 regulates sphingolipid metabolism in yeast mitochondria
-
Kitagaki H, Cowart LA, Matmati N, Vaena de Avalos S, Novgorodov SA, Zeidan YH, Bie-lawski J, Obeid LM, Hannun YA. Isc1 regulates sphingolipid metabolism in yeast mitochondria. Biochim Biophys Acta 2007; 1768: 2849-61.
-
(2007)
Biochim Biophys Acta
, vol.1768
, pp. 2849-2861
-
-
Kitagaki, H.1
Cowart, L.A.2
Matmati, N.3
de Avalos, S.V.4
Novgorodov, S.A.5
Zeidan, Y.H.6
Bie-Lawski, J.7
Obeid, L.M.8
Hannun, Y.A.9
-
56
-
-
0035907364
-
Biochemical characterization of the reverse activity of rat brain cera-midase. A CoA-independent and fumonisin B1-insensitive ceramide synthase
-
El Bawab S, Birbes H, Roddy P, Szulc ZM, Bie-lawska A, Hannun YA. Biochemical characterization of the reverse activity of rat brain cera-midase. A CoA-independent and fumonisin B1-insensitive ceramide synthase. J Biol Chem 2001; 276: 16758-66.
-
(2001)
J Biol Chem
, vol.276
, pp. 16758-16766
-
-
El-Bawab, S.1
Birbes, H.2
Roddy, P.3
Szulc, Z.M.4
Bie-Lawska, A.5
Hannun, Y.A.6
-
57
-
-
0034647935
-
Molecular cloning and characterization of a human mitochon-drial ceramidase
-
El Bawab S, Roddy P, Qian T, Bielawska A, Lemasters JJ, Hannun YA. Molecular cloning and characterization of a human mitochon-drial ceramidase. J Biol Chem 2000; 275: 21508-13.
-
(2000)
J Biol Chem
, vol.275
, pp. 21508-21513
-
-
El-Bawab, S.1
Roddy, P.2
Qian, T.3
Bielawska, A.4
Lemasters, J.J.5
Hannun, Y.A.6
-
58
-
-
79960117964
-
Novel pathway of ceramide production in mitochondria: Thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA
-
Novgorodov SA, Wu BX, Gudz TI, Bielawski J, Ovchinnikova TV, Hannun YA, Obeid LM. Novel pathway of ceramide production in mitochondria: thioesterase and neutral ceramidase produce ceramide from sphingosine and acyl-CoA. J Biol Chem 2011; 286: 25352-62.
-
(2011)
J Biol Chem
, vol.286
, pp. 25352-25362
-
-
Novgorodov, S.A.1
Wu, B.X.2
Gudz, T.I.3
Bielawski, J.4
Ovchinnikova, T.V.5
Hannun, Y.A.6
Obeid, L.M.7
-
59
-
-
42949105726
-
Ceramide synthesis in the endoplasmic reticulum can permeabilize mitochondria to proapoptotic proteins
-
Stiban J, Caputo L, Colombini M. Ceramide synthesis in the endoplasmic reticulum can permeabilize mitochondria to proapoptotic proteins. J Lipid Res 2008; 49: 625-34.
-
(2008)
J Lipid Res
, vol.49
, pp. 625-634
-
-
Stiban, J.1
Caputo, L.2
Colombini, M.3
-
60
-
-
0034704409
-
Lethal fore-brain ischemia stimulates sphingomyelin hydrolysis and ceramide generation in the gerbil hippocampus
-
Nakane M, Kubota M, Nakagomi T, Tamura A, Hisaki H, Shimasaki H, Ueta N. Lethal fore-brain ischemia stimulates sphingomyelin hydrolysis and ceramide generation in the gerbil hippocampus. Neurosci Lett 2000; 296: 89-92.
-
(2000)
Neurosci Lett
, vol.296
, pp. 89-92
-
-
Nakane, M.1
Kubota, M.2
Nakagomi, T.3
Tamura, A.4
Hisaki, H.5
Shimasaki, H.6
Ueta, N.7
-
61
-
-
0024405793
-
Accumulation of ceramide in ischemic human brain of an acute case of cerebral occlusion
-
Kubota M, Kitahara S, Shimasaki H, Ueta N. Accumulation of ceramide in ischemic human brain of an acute case of cerebral occlusion. Jpn J Exp Med 1989; 59: 59-64.
-
(1989)
Jpn J Exp Med
, vol.59
, pp. 59-64
-
-
Kubota, M.1
Kitahara, S.2
Shimasaki, H.3
Ueta, N.4
-
62
-
-
0029780817
-
Sphingomye-lin changes in rat cerebral cortex during focal ischemia
-
Kubota M, Narita K, Nakagomi T, Tamura A, Shimasaki H, Ueta N, Yoshida S. Sphingomye-lin changes in rat cerebral cortex during focal ischemia. Neurol Res 1996; 18: 337-41.
-
(1996)
Neurol Res
, vol.18
, pp. 337-341
-
-
Kubota, M.1
Narita, K.2
Nakagomi, T.3
Tamura, A.4
Shimasaki, H.5
Ueta, N.6
Yoshida, S.7
-
63
-
-
2642521387
-
Glucosylceramide synthase activity and cera-mide levels are modulated during cerebral ischemia after ischemic preconditioning
-
Takahashi K, Ginis I, Nishioka R, Klimanis D, Barone FC, White RF, Chen Y, Hallenbeck JM. Glucosylceramide synthase activity and cera-mide levels are modulated during cerebral ischemia after ischemic preconditioning. J Cereb Blood Flow Metab 2004; 24: 623-7.
-
(2004)
J Cereb Blood Flow Metab
, vol.24
, pp. 623-627
-
-
Takahashi, K.1
Ginis, I.2
Nishioka, R.3
Klimanis, D.4
Barone, F.C.5
White, R.F.6
Chen, Y.7
Hallenbeck, J.M.8
-
64
-
-
0034488193
-
Pivotal role for acidic sphingomyelinase in cerebral ischemia-induced ceramide and cytokine production, and neuronal apoptosis
-
Yu ZF, Nikolova-Karakashian M, Zhou D, Cheng G, Schuchman EH, Mattson MP. Pivotal role for acidic sphingomyelinase in cerebral ischemia-induced ceramide and cytokine production, and neuronal apoptosis. J Mol Neuro-sci 2000; 15: 85-97.
-
(2000)
J Mol Neuro-sci
, vol.15
, pp. 85-97
-
-
Yu, Z.F.1
Nikolova-Karakashian, M.2
Zhou, D.3
Cheng, G.4
Schuchman, E.H.5
Mattson, M.P.6
-
65
-
-
57649198325
-
Integrin-associated Lyn kinase promotes cell survival by suppressing acid sphingomyeli-nase activity
-
Chudakova DA, Zeidan YH, Wheeler BW, Yu J, Novgorodov SA, Kindy MS, Hannun YA, Gudz TI. Integrin-associated Lyn kinase promotes cell survival by suppressing acid sphingomyeli-nase activity. J Biol Chem 2008; 283: 28806-16.
-
(2008)
J Biol Chem
, vol.283
, pp. 28806-28816
-
-
Chudakova, D.A.1
Zeidan, Y.H.2
Wheeler, B.W.3
Yu, J.4
Novgorodov, S.A.5
Kindy, M.S.6
Hannun, Y.A.7
Gudz, T.I.8
-
66
-
-
4444374382
-
Upregula-tion of ceramide and its regulating mechanism in a rat model of chronic cerebral ischemia
-
Ohtani R, Tomimoto H, Kondo T, Wakita H, Akiguchi I, Shibasaki H, Okazaki T. Upregula-tion of ceramide and its regulating mechanism in a rat model of chronic cerebral ischemia. Brain Res 2004; 1023: 31-40.
-
(2004)
Brain Res
, vol.1023
, pp. 31-40
-
-
Ohtani, R.1
Tomimoto, H.2
Kondo, T.3
Wakita, H.4
Akiguchi, I.5
Shibasaki, H.6
Okazaki, T.7
-
67
-
-
7644230131
-
Future targets and cascades for neuroprotective strategies
-
Chan PH. Future targets and cascades for neuroprotective strategies. Stroke 2004; 35: 2748-50.
-
(2004)
Stroke
, vol.35
, pp. 2748-2750
-
-
Chan, P.H.1
-
68
-
-
43949134209
-
Eat your heart out: Role of autophagy in myocardial ische-mia/reperfusion
-
Gustafsson AB, Gottlieb RA. Eat your heart out: Role of autophagy in myocardial ische-mia/reperfusion. Autophagy 2008; 4: 416-21.
-
(2008)
Autophagy
, vol.4
, pp. 416-421
-
-
Gustafsson, A.B.1
Gottlieb, R.A.2
-
69
-
-
1642540210
-
The mitochondrial calcium uniporter is a highly selective ion channel
-
Kirichok Y, Krapivinsky G, Clapham DE. The mitochondrial calcium uniporter is a highly selective ion channel. Nature 2004; 427: 360-4.
-
(2004)
Nature
, vol.427
, pp. 360-364
-
-
Kirichok, Y.1
Krapivinsky, G.2
Clapham, D.E.3
-
70
-
-
0030001654
-
Permeability transition pore of the inner mitochondrial membrane can operate in two open states with different selectivities
-
Novgorodov SA, Gudz TI. Permeability transition pore of the inner mitochondrial membrane can operate in two open states with different selectivities. J Bioenerg Biomembr 1996; 28: 139-46.
-
(1996)
J Bioenerg Biomembr
, vol.28
, pp. 139-146
-
-
Novgorodov, S.A.1
Gudz, T.I.2
-
71
-
-
0034668844
-
Limitations of cyclosporin A inhibition of the permeability transition in CNS mitochondria
-
Brustovetsky N, Dubinsky JM. Limitations of cyclosporin A inhibition of the permeability transition in CNS mitochondria. J Neurosci 2000; 20: 8229-37.
-
(2000)
J Neurosci
, vol.20
, pp. 8229-8237
-
-
Brustovetsky, N.1
Dubinsky, J.M.2
-
72
-
-
0033995265
-
Dual responses of CNS mitochondria to elevated calcium
-
Brustovetsky N, Dubinsky JM. Dual responses of CNS mitochondria to elevated calcium. J Neurosci 2000; 20: 103-13.
-
(2000)
J Neurosci
, vol.20
, pp. 103-113
-
-
Brustovetsky, N.1
Dubinsky, J.M.2
-
73
-
-
54049089657
-
Long-chain ceramide is a potent inhibitor of the mitochon-drial permeability transition pore
-
Novgorodov SA, Gudz TI, Obeid LM. Long-chain ceramide is a potent inhibitor of the mitochon-drial permeability transition pore. J Biol Chem 2008; 283: 24707-17.
-
(2008)
J Biol Chem
, vol.283
, pp. 24707-24717
-
-
Novgorodov, S.A.1
Gudz, T.I.2
Obeid, L.M.3
-
74
-
-
0033017265
-
TNF-alpha pre-treatment prevents subsequent activation of cultured brain cells with TNF-alpha and hy-poxia via ceramide
-
Ginis I, Schweizer U, Brenner M, Liu J, Azzam N, Spatz M, Hallenbeck JM. TNF-alpha pre-treatment prevents subsequent activation of cultured brain cells with TNF-alpha and hy-poxia via ceramide. Am J Physiol 1999; 276: C1171-83.
-
(1999)
Am J Physiol
, vol.276
, pp. 1171-1183
-
-
Ginis, I.1
Schweizer, U.2
Brenner, M.3
Liu, J.4
Azzam, N.5
Spatz, M.6
Hallenbeck, J.M.7
-
75
-
-
0033976146
-
Hypoxic preconditioning protects cultured neurons against hypoxic stress via TNF-alpha and cera-mide
-
Liu J, Ginis I, Spatz M, Hallenbeck JM. Hypoxic preconditioning protects cultured neurons against hypoxic stress via TNF-alpha and cera-mide. Am J Physiol Cell Physiol 2000; 278: C144-53.
-
(2000)
Am J Physiol Cell Physiol
, vol.278
, pp. 144-153
-
-
Liu, J.1
Ginis, I.2
Spatz, M.3
Hallenbeck, J.M.4
-
76
-
-
55549135019
-
Ceramide generated by sphin-gomyelin hydrolysis and the salvage pathway is involved in hypoxia/reoxygenation-induced Bax redistribution to mitochondria in NT-2 cells
-
Jin J, Hou Q, Mullen TD, Zeidan YH, Bielawski J, Kraveka JM, Bielawska A, Obeid LM, Han-nun YA, Hsu YT. Ceramide generated by sphin-gomyelin hydrolysis and the salvage pathway is involved in hypoxia/reoxygenation-induced Bax redistribution to mitochondria in NT-2 cells. J Biol Chem 2008; 283: 26509-17.
-
(2008)
J Biol Chem
, vol.283
, pp. 26509-26517
-
-
Jin, J.1
Hou, Q.2
Mullen, T.D.3
Zeidan, Y.H.4
Bielawski, J.5
Kraveka, J.M.6
Bielawska, A.7
Obeid, L.M.8
Han-Nun, Y.A.9
Hsu, Y.T.10
-
77
-
-
0035092459
-
Cell permeable exogenous ceramide reduces infarct size in spontaneously hypertensive rats supporting in vitro studies that have implicated ceramide in induction of tolerance to ischemia
-
Furuya K, Ginis I, Takeda H, Chen Y, Hallen-beck JM. Cell permeable exogenous ceramide reduces infarct size in spontaneously hypertensive rats supporting in vitro studies that have implicated ceramide in induction of tolerance to ischemia. J Cereb Blood Flow Metab 2001; 21: 226-32.
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 226-232
-
-
Furuya, K.1
Ginis, I.2
Takeda, H.3
Chen, Y.4
Hallen-Beck, J.M.5
-
78
-
-
0035196451
-
The protective effect of ceramide in immature rat brain hy-poxia-ischemia involves up-regulation of bcl-2 and reduction of TUNEL-positive cells
-
Chen Y, Ginis I, Hallenbeck JM. The protective effect of ceramide in immature rat brain hy-poxia-ischemia involves up-regulation of bcl-2 and reduction of TUNEL-positive cells. J Cereb Blood Flow Metab 2001; 21: 34-40.
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 34-40
-
-
Chen, Y.1
Ginis, I.2
Hallenbeck, J.M.3
-
79
-
-
33845291120
-
Sphingosine kinases, sphingosine 1 -phosphate, apoptosis and diseases
-
Hait NC, Oskeritzian CA, Paugh SW, Milstien S, Spiegel S. Sphingosine kinases, sphingosine 1 -phosphate, apoptosis and diseases. Biochim Biophys Acta 2006; 1758: 2016-26.
-
(2006)
Biochim Biophys Acta
, vol.1758
, pp. 2016-2026
-
-
Hait, N.C.1
Oskeritzian, C.A.2
Paugh, S.W.3
Milstien, S.4
Spiegel, S.5
-
80
-
-
33845294390
-
A house divided: Ceramide, sphingosine, and sphingos-ine-1-phosphate in programmed cell death
-
Taha TA, Mullen TD, Obeid LM. A house divided: Ceramide, sphingosine, and sphingos-ine-1-phosphate in programmed cell death. Biochim Biophys Acta 2006; 1758: 2027-36.
-
(2006)
Biochim Biophys Acta
, vol.1758
, pp. 2027-2036
-
-
Taha, T.A.1
Mullen, T.D.2
Obeid, L.M.3
-
81
-
-
0036175596
-
Mitochondrial contributions to tissue damage in stroke
-
Sims NR, Anderson MF. Mitochondrial contributions to tissue damage in stroke. Neuro-chem Int 2002; 40: 511-26.
-
(2002)
Neuro-chem Int
, vol.40
, pp. 511-526
-
-
Sims, N.R.1
Anderson, M.F.2
-
82
-
-
34548627517
-
Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival
-
Yang H, Yang T, Baur JA, Perez E, Matsui T, Carmona JJ, Lamming DW, Souza-Pinto NC, Bohr VA, Rosenzweig A, de Cabo R, Sauve AA, Sinclair DA. Nutrient-sensitive mitochondrial NAD+ levels dictate cell survival. Cell 2007; 130: 1095-107.
-
(2007)
Cell
, vol.130
, pp. 1095-1107
-
-
Yang, H.1
Yang, T.2
Baur, J.A.3
Perez, E.4
Matsui, T.5
Carmona, J.J.6
Lamming, D.W.7
Souza-Pinto, N.C.8
Bohr, V.A.9
Rosenzweig, A.10
de Cabo, R.11
Sauve, A.A.12
Sinclair, D.A.13
-
83
-
-
0030856714
-
Direct inhibition of mitochondrial respiratory chain complex III by cell-permeable ceramide
-
Gudz TI, Tserng KY, Hoppel CL. Direct inhibition of mitochondrial respiratory chain complex III by cell-permeable ceramide. J Biol Chem 1997; 272: 24154-8.
-
(1997)
J Biol Chem
, vol.272
, pp. 24154-24158
-
-
Gudz, T.I.1
Tserng, K.Y.2
Hoppel, C.L.3
-
84
-
-
0034612304
-
Ceramide interaction with the respiratory chain of heart mitochondria
-
Di Paola M, Cocco T, Lorusso M. Ceramide interaction with the respiratory chain of heart mitochondria. Biochemistry 2000; 39: 6660-8.
-
(2000)
Biochemistry
, vol.39
, pp. 6660-6668
-
-
di Paola, M.1
Cocco, T.2
Lorusso, M.3
-
85
-
-
0037345809
-
Cytochrome c dissociation and release from mitochondria by truncated Bid and ceramide
-
Yuan H, Williams SD, Adachi S, Oltersdorf T, Gottlieb RA. Cytochrome c dissociation and release from mitochondria by truncated Bid and ceramide. Mitochondrion 2003; 2: 237-44.
-
(2003)
Mitochondrion
, vol.2
, pp. 237-244
-
-
Yuan, H.1
Williams, S.D.2
Adachi, S.3
Oltersdorf, T.4
Gottlieb, R.A.5
-
86
-
-
0035149749
-
Reactive oxygen radicals in signaling and damage in the ischemic brain
-
Chan PH. Reactive oxygen radicals in signaling and damage in the ischemic brain. J Cereb Blood Flow Metab 2001; 21: 2-14.
-
(2001)
J Cereb Blood Flow Metab
, vol.21
, pp. 2-14
-
-
Chan, P.H.1
-
87
-
-
0034740585
-
DeltaPsi(m)-Dependent and -independent production of reactive oxygen species by rat brain mitochondria
-
Votyakova TV, Reynolds IJ. DeltaPsi(m)-Dependent and -independent production of reactive oxygen species by rat brain mitochondria. J Neurochem 2001; 79: 266-77.
-
(2001)
J Neurochem
, vol.79
, pp. 266-277
-
-
Votyakova, T.V.1
Reynolds, I.J.2
-
88
-
-
1842330849
-
Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione
-
García-Ruiz C, Colell A, Marí M, Morales A, Fernández-Checa JC. Direct effect of ceramide on the mitochondrial electron transport chain leads to generation of reactive oxygen species. Role of mitochondrial glutathione. J Biol Chem 1997; 272: 11369-77.
-
(1997)
J Biol Chem
, vol.272
, pp. 11369-11377
-
-
García-Ruiz, C.1
Colell, A.2
Marí, M.3
Morales, A.4
Fernández-Checa, J.C.5
-
89
-
-
0031918742
-
The mitochondrial death/life regulator in apoptosis and necrosis
-
Kroemer G, Dallaporta B, Resche-Rigon M. The mitochondrial death/life regulator in apoptosis and necrosis. Annu Rev Physiol 1998; 60: 619-42.
-
(1998)
Annu Rev Physiol
, vol.60
, pp. 619-642
-
-
Kroemer, G.1
Dallaporta, B.2
Resche-Rigon, M.3
-
90
-
-
0033782296
-
Mitochondrial participation in ischemic and traumatic neural cell death
-
Fiskum G. Mitochondrial participation in ischemic and traumatic neural cell death. J Neurotrauma 2000; 17: 843-55.
-
(2000)
J Neurotrauma
, vol.17
, pp. 843-855
-
-
Fiskum, G.1
-
91
-
-
67649460932
-
Mitochon-drial membrane permeabilization in neuronal injury
-
Galluzzi L, Blomgren K, Kroemer G. Mitochon-drial membrane permeabilization in neuronal injury. Nat Rev Neurosci 2009; 10: 481-94.
-
(2009)
Nat Rev Neurosci
, vol.10
, pp. 481-494
-
-
Galluzzi, L.1
Blomgren, K.2
Kroemer, G.3
-
92
-
-
15844407874
-
Cyclophilin D-dependent mito-chondrial permeability transition regulates some necrotic but not apoptotic cell death
-
Nakagawa T, Shimizu S, Watanabe T, Yamagu-chi O, Otsu K, Yamagata H, Inohara H, Kubo T, Tsujimoto Y. Cyclophilin D-dependent mito-chondrial permeability transition regulates some necrotic but not apoptotic cell death. Nature 2005; 434: 652-8.
-
(2005)
Nature
, vol.434
, pp. 652-658
-
-
Nakagawa, T.1
Shimizu, S.2
Watanabe, T.3
Yamagu-Chi, O.4
Otsu, K.5
Yamagata, H.6
Inohara, H.7
Kubo, T.8
Tsujimoto, Y.9
-
93
-
-
24744460273
-
Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia
-
Schinzel AC, Takeuchi O, Huang Z, Fisher JK, Zhou Z, Rubens J, Hetz C, Danial NN, Mosko-witz MA, Korsmeyer SJ. Cyclophilin D is a component of mitochondrial permeability transition and mediates neuronal cell death after focal cerebral ischemia. Proc Natl Acad Sci USA 2005; 102: 12005-10.
-
(2005)
Proc Natl Acad Sci USA
, vol.102
, pp. 12005-12010
-
-
Schinzel, A.C.1
Takeuchi, O.2
Huang, Z.3
Fisher, J.K.4
Zhou, Z.5
Rubens, J.6
Hetz, C.7
Danial, N.N.8
Mosko-Witz, M.A.9
Korsmeyer, S.J.10
-
94
-
-
13844281067
-
The powerhouse takes control of the cell: Is the mitochondrial permeability transition a viable therapeutic target against neuronal dysfunction and death?
-
Stavrovskaya IG, Kristal BS. The powerhouse takes control of the cell: is the mitochondrial permeability transition a viable therapeutic target against neuronal dysfunction and death? Free Radic Biol Med 2005; 38: 687-97.
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 687-697
-
-
Stavrovskaya, I.G.1
Kristal, B.S.2
-
95
-
-
0033570890
-
Apop-tosis driven by IP(3)-linked mitochondrial calcium signals
-
Szalai G, Krishnamurthy R, Hajnoczky G. Apop-tosis driven by IP(3)-linked mitochondrial calcium signals. Embo J 1999; 18: 6349-61.
-
(1999)
Embo J
, vol.18
, pp. 6349-6361
-
-
Szalai, G.1
Krishnamurthy, R.2
Hajnoczky, G.3
-
96
-
-
0033615649
-
Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore
-
Pastorino JG, Tafani M, Rothman RJ, Mar-cinkeviciute A, Hoek JB, Farber JL. Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore. J Biol Chem 1999; 274: 31734-9.
-
(1999)
J Biol Chem
, vol.274
, pp. 31734-31739
-
-
Pastorino, J.G.1
Tafani, M.2
Rothman, R.J.3
Mar-Cinkeviciute, A.4
Hoek, J.B.5
Farber, J.L.6
-
97
-
-
0031005956
-
Ceramide induces hepatocyte cell death through disruption of mitochondrial function in the rat
-
Arora AS, Jones BJ, Patel TC, Bronk SF, Gores GJ. Ceramide induces hepatocyte cell death through disruption of mitochondrial function in the rat. Hepatology 1997; 25: 958-63.
-
(1997)
Hepatology
, vol.25
, pp. 958-963
-
-
Arora, A.S.1
Jones, B.J.2
Patel, T.C.3
Bronk, S.F.4
Gores, G.J.5
-
98
-
-
18144404605
-
Positively charged ceramide is a potent inducer of mitochondrial permeabilization
-
Novgorodov SA, Szulc ZM, Luberto C, Jones JA, Bielawski J, Bielawska A, Hannun YA, Obeid LM. Positively charged ceramide is a potent inducer of mitochondrial permeabilization. J Biol Chem 2005; 280: 16096-105.
-
(2005)
J Biol Chem
, vol.280
, pp. 16096-16105
-
-
Novgorodov, S.A.1
Szulc, Z.M.2
Luberto, C.3
Jones, J.A.4
Bielawski, J.5
Bielawska, A.6
Hannun, Y.A.7
Obeid, L.M.8
-
99
-
-
69149109036
-
AIF: Not just an apoptosis-inducing factor
-
Joza N, Pospisilik JA, Hangen E, Hanada T, Modjtahedi N, Penninger JM, Kroemer G. AIF: not just an apoptosis-inducing factor. Ann N Y Acad Sci 2009; 1171: 2-11.
-
(2009)
Ann N Y Acad Sci
, vol.1171
, pp. 2-11
-
-
Joza, N.1
Pospisilik, J.A.2
Hangen, E.3
Hanada, T.4
Modjtahedi, N.5
Penninger, J.M.6
Kroemer, G.7
-
100
-
-
0037269346
-
Two pathways for tBID-induced cytochrome c release from rat brain mitochondria: BAK- versus BAX-dependence
-
Brustovetsky N, Dubinsky JM, Antonsson B, Jemmerson R. Two pathways for tBID-induced cytochrome c release from rat brain mitochondria: BAK- versus BAX-dependence. J Neuro-chem 2003; 84: 196-207.
-
(2003)
J Neuro-chem
, vol.84
, pp. 196-207
-
-
Brustovetsky, N.1
Dubinsky, J.M.2
Antonsson, B.3
Jemmerson, R.4
-
101
-
-
76849107125
-
Mitochondrial calpain system: An overview
-
Kar P, Samanta K, Shaikh S, Chowdhury A, Chakraborti T, Chakraborti S. Mitochondrial calpain system: an overview. Arch Biochem Biophys 2010; 495: 1-7.
-
(2010)
Arch Biochem Biophys
, vol.495
, pp. 1-7
-
-
Kar, P.1
Samanta, K.2
Shaikh, S.3
Chowdhury, A.4
Chakraborti, T.5
Chakraborti, S.6
-
102
-
-
3543150124
-
Ceramide induces release of pro-apoptotic proteins from mitochondria by either a Ca2+ -dependent or a Ca2+ -independent mechanism
-
Di Paola M, Zaccagnino P, Montedoro G, Cocco T, Lorusso M. Ceramide induces release of pro-apoptotic proteins from mitochondria by either a Ca2+ -dependent or a Ca2+ -independent mechanism. J Bioenerg Biomembr 2004; 36: 165-70.
-
(2004)
J Bioenerg Biomembr
, vol.36
, pp. 165-170
-
-
di Paola, M.1
Zaccagnino, P.2
Montedoro, G.3
Cocco, T.4
Lorusso, M.5
-
103
-
-
0034623715
-
The lipids C2- and C16-ceramide form large stable channels. Implications for apoptosis
-
Siskind LJ, Colombini M. The lipids C2- and C16-ceramide form large stable channels. Implications for apoptosis. J Biol Chem 2000; 275: 38640-4.
-
(2000)
J Biol Chem
, vol.275
, pp. 38640-38644
-
-
Siskind, L.J.1
Colombini, M.2
-
104
-
-
0037178790
-
Cera-mide channels increase the permeability of the mitochondrial outer membrane to small proteins
-
Siskind LJ, Kolesnick RN, Colombini M. Cera-mide channels increase the permeability of the mitochondrial outer membrane to small proteins. J Biol Chem 2002; 277: 26796-803.
-
(2002)
J Biol Chem
, vol.277
, pp. 26796-26803
-
-
Siskind, L.J.1
Kolesnick, R.N.2
Colombini, M.3
-
105
-
-
33745037188
-
Cera-mide forms channels in mitochondrial outer membranes at physiologically relevant concentrations
-
Siskind LJ, Kolesnick RN, Colombini M. Cera-mide forms channels in mitochondrial outer membranes at physiologically relevant concentrations. Mitochondrion 2006; 6: 118-25.
-
(2006)
Mitochondrion
, vol.6
, pp. 118-125
-
-
Siskind, L.J.1
Kolesnick, R.N.2
Colombini, M.3
-
106
-
-
0033525685
-
Ceramide induces cytochrome c release from isolated mitochondria. Importance of mitochondrial redox state
-
Ghafourifar P, Klein SD, Schucht O, Schenk U, Pruschy M, Rocha S, Richter C. Ceramide induces cytochrome c release from isolated mitochondria. Importance of mitochondrial redox state. J Biol Chem 1999; 274: 6080-4.
-
(1999)
J Biol Chem
, vol.274
, pp. 6080-6084
-
-
Ghafourifar, P.1
Klein, S.D.2
Schucht, O.3
Schenk, U.4
Pruschy, M.5
Rocha, S.6
Richter, C.7
-
107
-
-
0037023765
-
Membrane restructuring via ceramide results in enhanced solute efflux
-
Montes LR, Ruiz-Argüello MB, Goñi FM, Alonso A. Membrane restructuring via ceramide results in enhanced solute efflux. J Biol Chem 2002; 277: 11788-94.
-
(2002)
J Biol Chem
, vol.277
, pp. 11788-11794
-
-
Montes, L.R.1
Ruiz-Argüello, M.B.2
Goñi, F.M.3
Alonso, A.4
-
108
-
-
43749120533
-
Anti-apoptotic Bcl-2 Family Proteins Disassemble Ceramide Channels
-
Siskind LJ, Feinstein L, Yu T, Davis JS, Jones D, Choi J, Zuckerman JE, Tan W, Hill RB, Hard-wick JM, Colombini M. Anti-apoptotic Bcl-2 Family Proteins Disassemble Ceramide Channels. J Biol Chem 2008; 283: 6622-30.
-
(2008)
J Biol Chem
, vol.283
, pp. 6622-6630
-
-
Siskind, L.J.1
Feinstein, L.2
Yu, T.3
Davis, J.S.4
Jones, D.5
Choi, J.6
Zuckerman, J.E.7
Tan, W.8
Hill, R.B.9
Hard-Wick, J.M.10
Colombini, M.11
-
109
-
-
0037345809
-
Cytochrome c dissociation and release from mitochondria by trancated Bid and ceramide
-
Yuan H, Williams S., Adachi S, Oltersdorf T, Gottlieb RA. Cytochrome c dissociation and release from mitochondria by trancated Bid and ceramide. Mitochondrion 2003; 2: 237-244.
-
(2003)
Mitochondrion
, vol.2
, pp. 237-244
-
-
Yuan, H.1
Williams, S.2
Adachi, S.3
Oltersdorf, T.4
Gottlieb, R.A.5
-
110
-
-
0033551668
-
Apoptogenic ganglioside GD3 directly induces the mitochondrial permeability transition
-
Kristal BS, Brown AM. Apoptogenic ganglioside GD3 directly induces the mitochondrial permeability transition. J Biol Chem 1999; 274: 23169-75.
-
(1999)
J Biol Chem
, vol.274
, pp. 23169-23175
-
-
Kristal, B.S.1
Brown, A.M.2
-
111
-
-
0033615649
-
Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore
-
Pastorino JG, Tafani M, Rothman RJ, Mar-cinkeviciute A, Hoek JB, Farber JL. Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore. J Biol Chem 1999; 274: 31734-9.
-
(1999)
J Biol Chem
, vol.274
, pp. 31734-31739
-
-
Pastorino, J.G.1
Tafani, M.2
Rothman, R.J.3
Mar-Cinkeviciute, A.4
Hoek, J.B.5
Farber, J.L.6
-
112
-
-
38049098527
-
A novel role for protein kinase Cdelta-mediated phosphorylation of acid sphingomyelinase in UV light-induced mito-chondrial injury
-
Zeidan YH, Wu BX, Jenkins RW, Obeid LM, Hannun YA. A novel role for protein kinase Cdelta-mediated phosphorylation of acid sphingomyelinase in UV light-induced mito-chondrial injury. Faseb J 2008; 22: 183-93.
-
(2008)
Faseb J
, vol.22
, pp. 183-193
-
-
Zeidan, Y.H.1
Wu, B.X.2
Jenkins, R.W.3
Obeid, L.M.4
Hannun, Y.A.5
-
113
-
-
38849095253
-
Changes in mitochon-drial dynamics during ceramide-induced car- diomyocyte early apoptosis
-
Parra V, Eisner V, Chiong M, Criollo A, Moraga F, Garcia A, Härtel S, Jaimovich E, Zorzano A, Hidalgo C, Lavandero S. Changes in mitochon- drial dynamics during ceramide-induced car- diomyocyte early apoptosis. Cardiovasc Res 2008; 77: 387-97.
-
(2008)
Cardiovasc Res
, vol.77
, pp. 387-397
-
-
Parra, V.1
Eisner, V.2
Chiong, M.3
Criollo, A.4
Moraga, F.5
Garcia, A.6
Härtel, S.7
Jaimovich, E.8
Zorzano, A.9
Hidalgo, C.10
Lavandero, S.11
-
114
-
-
45349094984
-
Mitochondrial dynamics and apoptosis
-
Suen DF, Norris KL, Youle RJ. Mitochondrial dynamics and apoptosis. Genes Dev 2008; 22: 1577-90.
-
(2008)
Genes Dev
, vol.22
, pp. 1577-1590
-
-
Suen, D.F.1
Norris, K.L.2
Youle, R.J.3
-
115
-
-
0028894725
-
In situ detection of DNA fragmentation after focal cerebral ischemia in mice
-
Li Y, Chopp M, Jiang N, Zaloga C. In situ detection of DNA fragmentation after focal cerebral ischemia in mice. Brain Res Mol Brain Res 1995; 28: 164-8.
-
(1995)
Brain Res Mol Brain Res
, vol.28
, pp. 164-168
-
-
Li, Y.1
Chopp, M.2
Jiang, N.3
Zaloga, C.4
-
116
-
-
0030725897
-
The immunosuppressant drug FK506 ameliorates secondary mitochondrial dysfunction following transient focal cerebral ischemia in the rat
-
Nakai A, Kuroda S, Kristián T, Siesjö BK. The immunosuppressant drug FK506 ameliorates secondary mitochondrial dysfunction following transient focal cerebral ischemia in the rat. Neurobiol Dis 1997; 4: 288-300.
-
(1997)
Neurobiol Dis
, vol.4
, pp. 288-300
-
-
Nakai, A.1
Kuroda, S.2
Kristián, T.3
Siesjö, B.K.4
-
117
-
-
0037163856
-
New advances on structural and biological functions of ceramide in apoptotic/ necrotic cell death and cancer
-
Mimeault M. New advances on structural and biological functions of ceramide in apoptotic/ necrotic cell death and cancer. FEBS Lett 2002; 530: 9-16.
-
(2002)
FEBS Lett
, vol.530
, pp. 9-16
-
-
Mimeault, M.1
-
118
-
-
34047242070
-
Sphingolipids and cell death
-
Morales A, Lee H, Goñi FM, Kolesnick R, Fer-nandez-Checa JC. Sphingolipids and cell death. Apoptosis 2007; 12: 923-39.
-
(2007)
Apoptosis
, vol.12
, pp. 923-939
-
-
Morales, A.1
Lee, H.2
Goñi, F.M.3
Kolesnick, R.4
Fer-nandez-Checa, J.C.5
-
119
-
-
0035736259
-
Organelle-specific initiation of cell death pathways
-
Ferri KF, Kroemer G. Organelle-specific initiation of cell death pathways. Nat Cell Biol 2001; 3: E255-63.
-
(2001)
Nat Cell Biol
, vol.3
, pp. 255-263
-
-
Ferri, K.F.1
Kroemer, G.2
-
120
-
-
0034682695
-
Apoptosis. Mitochon-dria-the death signal integrators
-
Brenner C, Kroemer G. Apoptosis. Mitochon-dria-the death signal integrators. Science 2000; 289: 1150-1.
-
(2000)
Science
, vol.289
, pp. 1150-1151
-
-
Brenner, C.1
Kroemer, G.2
-
121
-
-
33845977959
-
Mitochon-drial membrane permeabilization in cell death
-
Kroemer G, Galluzzi L, Brenner C. Mitochon-drial membrane permeabilization in cell death. Physiol Rev 2007; 87: 99-163.
-
(2007)
Physiol Rev
, vol.87
, pp. 99-163
-
-
Kroemer, G.1
Galluzzi, L.2
Brenner, C.3
-
122
-
-
0036790735
-
Mitochondrial cyto-chrome c release precedes transmembrane depolarisation and caspase-3 activation during ceramide-induced apoptosis of Jurkat T cells
-
Hearps AC, Burrows J, Connor CE, Woods GM, Lowenthal RM, Ragg SJ. Mitochondrial cyto-chrome c release precedes transmembrane depolarisation and caspase-3 activation during ceramide-induced apoptosis of Jurkat T cells. Apoptosis 2002; 7: 387-94.
-
(2002)
Apoptosis
, vol.7
, pp. 387-394
-
-
Hearps, A.C.1
Burrows, J.2
Connor, C.E.3
Woods, G.M.4
Lowenthal, R.M.5
Ragg, S.J.6
-
123
-
-
38049080087
-
Ceramide induces release of mitochondrial proapoptotic proteins in caspase-dependent and -independent manner in HT-29 cells
-
Zhang X, Li B, Zhang Y, Liu J. Ceramide induces release of mitochondrial proapoptotic proteins in caspase-dependent and -independent manner in HT-29 cells. Sci China C Life Sci 2008; 51: 66-71.
-
(2008)
Sci China C Life Sci
, vol.51
, pp. 66-71
-
-
Zhang, X.1
Li, B.2
Zhang, Y.3
Liu, J.4
-
124
-
-
33646589316
-
Sphingolipid signaling and redox regulation
-
Won JS, Singh I. Sphingolipid signaling and redox regulation. Free Radic Biol Med 2006; 40: 1875-88.
-
(2006)
Free Radic Biol Med
, vol.40
, pp. 1875-1888
-
-
Won, J.S.1
Singh, I.2
-
125
-
-
0035863104
-
Oxidation of pyridine nucleotides during Fas- and ceramide-induced apoptosis in Jur- kat cells: Correlation with changes in mito chondria, glutathione depletion, intracellular acidification and caspase 3 activation
-
Gendron MC, Schrantz N, Métivier D, Kroemer G, Maciorowska Z, Sureau F, Koester S, Petit PX. Oxidation of pyridine nucleotides during Fas- and ceramide-induced apoptosis in Jur- kat cells: correlation with changes in mito chondria, glutathione depletion, intracellular acidification and caspase 3 activation. Bio- chem J 2001; 353: 357-67.
-
(2001)
Bio- Chem J
, vol.353
, pp. 357-367
-
-
Gendron, M.C.1
Schrantz, N.2
Métivier, D.3
Kroemer, G.4
Maciorowska, Z.5
Sureau, F.6
Koester, S.7
Petit, P.X.8
-
126
-
-
4644314416
-
Sequential caspase-2 and caspase-8 activation up-stream of mitochondria during ceramideand etoposide-induced apoptosis
-
Lin CF, Chen CL, Chang WT, Jan MS, Hsu LJ, Wu RH, Tang MJ, Chang WC, Lin YS. Sequential caspase-2 and caspase-8 activation up-stream of mitochondria during ceramideand etoposide-induced apoptosis. J Biol Chem 2004; 279: 40755-61.
-
(2004)
J Biol Chem
, vol.279
, pp. 40755-40761
-
-
Lin, C.F.1
Chen, C.L.2
Chang, W.T.3
Jan, M.S.4
Hsu, L.J.5
Wu, R.H.6
Tang, M.J.7
Chang, W.C.8
Lin, Y.S.9
-
127
-
-
0029101644
-
Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death
-
Zamzami N, Marchetti P, Castedo M, De-caudin D, Macho A, Hirsch T, Susin SA, Petit PX, Mignotte B, Kroemer G. Sequential reduction of mitochondrial transmembrane potential and generation of reactive oxygen species in early programmed cell death. J Exp Med 1995; 182: 367-77.
-
(1995)
J Exp Med
, vol.182
, pp. 367-377
-
-
Zamzami, N.1
Marchetti, P.2
Castedo, M.3
De-Caudin, D.4
Macho, A.5
Hirsch, T.6
Susin, S.A.7
Petit, P.X.8
Mignotte, B.9
Kroemer, G.10
-
128
-
-
0037354119
-
Ceramide-induced neuronal apoptosis is associated with dephosphorylation of Akt, BAD, FKHR, GSK-3beta, and induction of the mitochondrial-dependent intrinsic caspase pathway
-
Stoica BA, Movsesyan VA, Lea PM, Faden AI. Ceramide-induced neuronal apoptosis is associated with dephosphorylation of Akt, BAD, FKHR, GSK-3beta, and induction of the mitochondrial-dependent intrinsic caspase pathway. Mol Cell Neurosci 2003; 22: 365-82.
-
(2003)
Mol Cell Neurosci
, vol.22
, pp. 365-382
-
-
Stoica, B.A.1
Movsesyan, V.A.2
Lea, P.M.3
Faden, A.I.4
-
129
-
-
0029982148
-
The cytotox-icity of tumor necrosis factor depends on induction of the mitochondrial permeability transition
-
Pastorino JG, Simbula G, Yamamoto K, Glas-cott PA, Rothman RJ, Farber JL. The cytotox-icity of tumor necrosis factor depends on induction of the mitochondrial permeability transition. J Biol Chem 1996; 271: 29792-8.
-
(1996)
J Biol Chem
, vol.271
, pp. 29792-29798
-
-
Pastorino, J.G.1
Simbula, G.2
Yamamoto, K.3
Glas-Cott, P.A.4
Rothman, R.J.5
Farber, J.L.6
-
130
-
-
0035421320
-
Propagation of the apoptotic signal by mitochondrial waves
-
Pacher P, Hajnoczky G. Propagation of the apoptotic signal by mitochondrial waves. Embo J 2001; 20: 4107-21.
-
(2001)
Embo J
, vol.20
, pp. 4107-4121
-
-
Pacher, P.1
Hajnoczky, G.2
-
131
-
-
0031013786
-
Ceramides induce a form of apoptosis in human acute lymphoblastic leukemia cells that is inhibited by Bcl-2, but not by CrmA
-
Geley S, Hartmann BL, Kofler R. Ceramides induce a form of apoptosis in human acute lymphoblastic leukemia cells that is inhibited by Bcl-2, but not by CrmA. FEBS Lett 1997; 400: 15-8.
-
(1997)
FEBS Lett
, vol.400
, pp. 15-18
-
-
Geley, S.1
Hartmann, B.L.2
Kofler, R.3
-
132
-
-
9344222195
-
Bcl-2 interrupts the ceramide-mediated pathway of cell death
-
Zhang J, Alter N, Reed JC, Borner C, Obeid LM, Hannun YA. Bcl-2 interrupts the ceramide-mediated pathway of cell death. Proc Natl Acad Sci USA 1996; 93: 5325-8.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 5325-5328
-
-
Zhang, J.1
Alter, N.2
Reed, J.C.3
Borner, C.4
Obeid, L.M.5
Hannun, Y.A.6
-
133
-
-
0033529534
-
Differential modulation of apoptosis sensitivity in CD95 type I and type II cells
-
Scaffidi C, Schmitz I, Zha J, Korsmeyer SJ, Krammer PH, Peter ME. Differential modulation of apoptosis sensitivity in CD95 type I and type II cells. J Biol Chem 1999; 274: 22532-8.
-
(1999)
J Biol Chem
, vol.274
, pp. 22532-22538
-
-
Scaffidi, C.1
Schmitz, I.2
Zha, J.3
Korsmeyer, S.J.4
Krammer, P.H.5
Peter, M.E.6
-
134
-
-
15944425766
-
A mitochondrial pool of sphingomyelin is involved in TNFalpha-induced Bax translocation to mitochondria
-
Birbes H, Luberto C, Hsu YT, El Bawab S, Han-nun YA, Obeid LM. A mitochondrial pool of sphingomyelin is involved in TNFalpha-induced Bax translocation to mitochondria. Biochem J 2005; 386: 445-51.
-
(2005)
Biochem J
, vol.386
, pp. 445-451
-
-
Birbes, H.1
Luberto, C.2
Hsu, Y.T.3
El-Bawab, S.4
Han-Nun, Y.A.5
Obeid, L.M.6
-
135
-
-
20444416324
-
An increase in the ATP levels occurs in cerebellar granule cells en route to apop-tosis in which ATP derives from both oxidative phosphorylation and anaerobic glycolysis
-
Atlante A, Giannattasio S, Bobba A, Gagliardi S, Petragallo V, Calissano P, Marra E, Pas-sarella S. An increase in the ATP levels occurs in cerebellar granule cells en route to apop-tosis in which ATP derives from both oxidative phosphorylation and anaerobic glycolysis. Biochim Biophys Acta 2005; 1708: 50-62.
-
(2005)
Biochim Biophys Acta
, vol.1708
, pp. 50-62
-
-
Atlante, A.1
Giannattasio, S.2
Bobba, A.3
Gagliardi, S.4
Petragallo, V.5
Calissano, P.6
Marra, E.7
Pas-Sarella, S.8
-
136
-
-
0030613796
-
Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria
-
Van der Heiden MG, Chandel NS, Williamson EK, Schumacker PT, Thompson CB. Bcl-xL regulates the membrane potential and volume homeostasis of mitochondria. Cell 1997; 91: 627-37.
-
(1997)
Cell
, vol.91
, pp. 627-637
-
-
van der Heiden, M.G.1
Chandel, N.S.2
Williamson, E.K.3
Schumacker, P.T.4
Thompson, C.B.5
-
137
-
-
33845337981
-
Calpain 10: A mitochondrial calpain and its role in calcium-induced mitochondrial dysfunction
-
Arrington DD, Van Vleet TR, Schnellmann RG. Calpain 10: a mitochondrial calpain and its role in calcium-induced mitochondrial dysfunction. Am J Physiol Cell Physiol 2006; 291: C1159-71.
-
(2006)
Am J Physiol Cell Physiol
, vol.291
, pp. 1159-71
-
-
Arrington, D.D.1
van Vleet, T.R.2
Schnellmann, R.G.3
|