Ceramide synthases 2, 5, and 6 confer distinct roles in radiation-induced apoptosis in HeLa cells

Cellular Signalling

Volumn 22, Issue 9, 2010, Pages 1300-1307

  Mesicek, Judith ^a   Lee, Hyunmi ^a   Feldman, Taya ^a   Jiang, Xuejun ^a   Skobeleva, Anastasia ^b   Berdyshev, Evgeny V ^b   Haimovitz Friedman, Adriana ^a   Fuks, Zvi ^a   Kolesnick, Richard ^a  

^a MEMORIAL SLOAN KETTERING CANCER CENTER   (United States)

^b UNIVERSITY OF CHICAGO   (United States)

Author keywords

Apoptosis; Ceramide synthase; CerS; HeLa cell; Ionizing radiation; LASS

Indexed keywords

CERAMIDE; CERAMIDE SYNTHASE 2; CERAMIDE SYNTHASE 5; CERAMIDE SYNTHASE 6; ENZYME; ISOENZYME; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL PROTECTION; CELL STRESS; CELL TYPE; CELLULAR DISTRIBUTION; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME SUBSTRATE; HELA CELL; HUMAN; HUMAN CELL; IMMUNOPRECIPITATION; IONIZING RADIATION; LIPOGENESIS; MITOCHONDRIAL MEMBRANE; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TISSUE DISTRIBUTION;

ACYL COENZYME A; APOPTOSIS; CERAMIDES; HELA CELLS; HUMANS; ISOENZYMES; MEMBRANE PROTEINS; MITOCHONDRIA; PALMITOYL COENZYME A; RADIATION, IONIZING; SPHINGOSINE N-ACYLTRANSFERASE; TUMOR SUPPRESSOR PROTEINS;

MAMMALIA;

EID: 77953728877     PISSN: 08986568     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cellsig.2010.04.006     Document Type: Article

References (56)

1. Bose R., Verheij M., Haimovitz-Friedman A., Scotto K., Fuks Z., Kolesnick R. Cell 1995, 82:405.
2. Jenkins G.M., Cowart L.A., Signorelli P., Pettus B.J., Chalfant C.E., Hannun Y.A. J. Biol. Chem. 2002, 277:42572.
3. Yu J., Novgorodov S.A., Chudakova D., Zhu H., Bielawska A., Bielawski J., Obeid L.M., Kindy M.S., Gudz T.I. J. Biol. Chem. 2007, 282:25940.
4. Rotolo J.A., Zhang J., Donepudi M., Lee H., Fuks Z., Kolesnick R. J. Biol. Chem. 2005, 280:26425.
5. Truman J.P., Gueven N., Lavin M., Leibel S., Kolesnick R., Fuks Z., Haimovitz-Friedman A. J. Biol. Chem. 2005, 280:23262.
6. Obeid L.M., Linardic C.M., Karolak L.A., Hannun Y.A. Science 1993, 259:1769.
7. Dbaibo G.S. Biochem. Soc. Trans. 1997, 25:557.
8. Pettus B.J., Chalfant C.E., Hannun Y.A. Biochim. Biophys. Acta 2002, 1585:114.
9. Hannun Y.A., Obeid L.M. Nat. Rev. Mol. Cell Biol. 2008, 9:139.
10. Merrill A.H., Liotta D.C., Riley R.T. Trends Cell Biol. 1996, 6:218.
11. Liao W.C., Haimovitz-Friedman A., Persaud R.S., McLoughlin M., Ehleiter D., Zhang N., Gatei M., Lavin M., Kolesnick R., Fuks Z. J. Biol. Chem. 1999, 274:17908.
12. Deng X., Yin X., Allan R., Lu D.D., Maurer C.W., Haimovitz-Friedman A., Fuks Z., Shaham S., Kolesnick R. Science 2008, 322:110.
13. Gross A., McDonnell J.M., Korsmeyer S.J. Genes Dev. 1999, 13:1899.
14. Green D.R., Kroemer G. Science 2004, 305:626.
15. Jourdain A., Martinou J.C. Int. J. Biochem. Cell Biol. 2009, 41:1884.
16. Motoyama N., Wang F., Roth K.A., Sawa H., Nakayama K., Negishi I., Senju S., Zhang Q., Fujii S., et al. Science 1995, 267:1506.
17. Hon H., Rucker E.B., Hennighausen L., Jacob J. J. Immunol. 2004, 173:4425.
18. Breckenridge D.G., Xue D. Curr. Opin. Cell Biol. 2004, 16:647.
19. Hwang D., Popat R., Bragdon C., O'Donnell K.E., Sonis S.T. Oral Surg. Oral Med. Oral Pathol. Oral Radiol. Endod. 2005, 100:321.
20. Petrache I., Natarajan V., Zhen L., Medler T.R., Richter A.T., Cho C., Hubbard W.C., Berdyshev E.V., Tuder R.M. Nat. Med. 2005, 11:491.
21. Cuzzocrea S., Di Paola R., Genovese T., Mazzon E., Esposito E., Crisafulli C., Bramanti P., Salvemini D. J. Pharmacol. Exp. Ther. 2008, 327:45.
22. Masini E., Giannini L., Nistri S., Cinci L., Mastroianni R., Xu W., Comhair S.A., Li D., Cuzzocrea S., Matuschak G.M., Salvemini D. J. Pharmacol. Exp. Ther. 2008, 324:548.
23. Uehara K., Miura S., Takeuchi T., Taki T., Nakashita M., Adachi M., Inamura T., Ogawa T., Akiba Y., Suzuki H., Nagata H., Ishii H. J. Pharmacol. Exp. Ther. 2003, 305:232.
24. Ch'ang H.J., Maj J.G., Paris F., Xing H.R., Zhang J., Truman J.P., Cardon-Cardo C., Haimovitz-Friedman A., Kolesnick R., Fuks Z. Nat. Med. 2005, 11:484.
25. Lahiri S., Lee H., Mesicek J., Fuks Z., Haimovitz-Friedman A., Kolesnick R.N., Futerman A.H. FEBS Lett. 2007, 581:5289.
26. Venkataraman K., Riebeling C., Bodennec J., Riezman H., Allegood J.C., Sullards M.C., Merrill A.H., Futerman A.H. J. Biol. Chem. 2002, 277:35642.
27. Riebeling C., Allegood J.C., Wang E., Merrill A.H., Futerman A.H. J. Biol. Chem. 2003, 278:43452.
28. Mizutani Y., Kihara A., Igarashi Y. Biochem. J. 2005, 390:263.
29. Mizutani Y., Kihara A., Igarashi Y. Biochem. J. 2006, 398:531.
30. Mizutani Y., Kihara A., Chiba H., Tojo H., Igarashi Y. J. Lipid Res. 2008, 49:2356.
31. Laviad E.L., Albee L., Pankova-Kholmyansky I., Epstein S., Park H., Merrill A.H., Futerman A.H. J. Biol. Chem. 2008, 283:5677.
32. Pettus B.J., Bielawska A., Kroesen B.J., Moeller P.D., Szulc Z.M., Hannun Y.A., Busman M. Rapid Commun. Mass Spectrom. 2003, 17:1203.
33. Pettus B.J., Baes M., Busman M., Hannun Y.A., Van Veldhoven P.P. Rapid Commun. Mass Spectrom. 2004, 18:1569.
34. Pewzner-Jung Y., Park H., Laviad E.L., Silva L.C., Lahiri S., Stiban J., Erez-Roman R., Brugger B., Sachsenheimer T., Wieland F., Prieto M., Merrill A.H., Futerman A.H. J. Biol. Chem. 2010, 285:10902.
35. Spassieva S.D., Mullen T.D., Townsend D.M., Obeid L.M. Biochem. J. 2009, 424:273.
36. Pewzner-Jung Y., Brenner O., Braun S., Laviad E.L., Ben-Dor S., Feldmesser E., Horn-Saban S., Amann-Zalcenstein D., Raanan C., Berkutzki T., Erez-Roman R., Ben-David O., Levy M., Holzman D., Park H., Nyska A., Merrill A.H., Futerman A.H. J. Biol. Chem. 2010, 285:10911.
37. Mandon E.C., Ehses I., Rother J., van Echten G., Sandhoff K. J. Biol. Chem. 1992, 267:11144.
38. Hirschberg K., Rodger J., Futerman A.H. Biochem. J. 1993, 290(Pt 3):751.
39. White-Gilbertson S., Mullen T., Senkal C., Lu P., Ogretmen B., Obeid L., Voelkel-Johnson C. Oncogene 2009, 28:1132.
40. Bionda C., Portoukalian J., Schmitt D., Rodriguez-Lafrasse C., Ardail D. Biochem. J. 2004, 382:527.
41. Koybasi S., Senkal C.E., Sundararaj K., Spassieva S., Bielawski J., Osta W., Day T.A., Jiang J.C., Jazwinski S.M., Hannun Y.A., Obeid L.M., Ogretmen B. J. Biol. Chem. 2004, 279:44311.
42. Senkal C.E., Ponnusamy S., Bielawski J., Hannun Y.A., Ogretmen B. FASEB J. 2010, 24:296.
43. Hayashi T., Rizzuto R., Hajnoczky G., Su T.P. Trends Cell Biol. 2009, 19:81.
44. Stiban J., Caputo L., Colombini M. J. Lipid Res. 2008, 49:625.
45. Vance J.E. J. Biol. Chem. 1990, 265:7248.
46. Bose R., Kolesnick R. Methods Enzymol. 2000, 322:373.
47. Cremesti A., Paris F., Grassme H., Holler N., Tschopp J., Fuks Z., Gulbins E., Kolesnick R. J. Biol. Chem. 2001, 276:23954.
48. Gao Z., Shao Y., Jiang X. J. Biol. Chem. 2005, 280:38271.
49. Shao Y., Gao Z., Marks P.A., Jiang X. Proc. Natl. Acad. Sci.U. S. A. 2004, 101:18030.
50. Pan W., da Graca L.S., Shao Y., Yin Q., Wu H., Jiang X. J. Biol. Chem. 2009, 284:6946.
51. Berdyshev E.V., Gorshkova I.A., Usatyuk P., Zhao Y., Saatian B., Hubbard W., Natarajan V. Cell. Signal. 2006, 18:1779.
52. Berdyshev E.V., Gorshkova I., Skobeleva A., Bittman R., Lu X., Dudek S.M., Mirzapoiazova T., Garcia J.G., Natarajan V. J. Biol. Chem. 2009, 284:5467.
53. Garcia-Barros M., Paris F., Cordon-Cardo C., Lyden D., Rafii S., Haimovitz-Friedman A., Fuks Z., Kolesnick R. Science 2003, 300:1155.
54. Vallee B., Riezman H. EMBO J. 2005, 24:730.
55. Taha T.A., Mullen T.D., Obeid L.M. Biochim. Biophys. Acta 2006, 1758:2027.
56. Renert A.F., Leprince P., Dieu M., Renaut J., Raes M., Bours V., Chapelle J.P., Piette J., Merville M.P., Fillet M. J. Proteome Res. 2009, 8:4810.