메뉴 건너뛰기




Volumn 24, Issue 6, 2004, Pages 623-627

Glucosylceramide synthase activity and ceramide levels are modulated during cerebral ischemia after ischemic preconditioning

Author keywords

Ceramide; Glucosylceramide synthase; Ischemic tolerance; Middle cerebral artery occlusion; Spontaneously hypertensive rats

Indexed keywords

CERAMIDE; CERAMIDE GLUCOSYLTRANSFERASE;

EID: 2642521387     PISSN: 0271678X     EISSN: None     Source Type: Journal    
DOI: 10.1097/01.WCB.0000119990.06999.A9     Document Type: Article
Times cited : (33)

References (48)
  • 1
    • 0030038402 scopus 로고    scopus 로고
    • Induction of glucosylceramide synthase by synthase inhibitors and ceramide
    • Abe A, Radin NS, Shayman JA (1996) Induction of glucosylceramide synthase by synthase inhibitors and ceramide. Biochim Biophys Acta 1299:333-341
    • (1996) Biochim Biophys Acta , vol.1299 , pp. 333-341
    • Abe, A.1    Radin, N.S.2    Shayman, J.A.3
  • 4
    • 0031657749 scopus 로고    scopus 로고
    • Ischemic preconditioning and brain tolerance: Temporal histological and functional outcomes, protein synthesis requirement, and interleukin-1 receptor antagonist and early gene expression
    • discussion 1950-1931
    • Barone FC, White RF, Spera PA, Ellison J, Currie RW, Wang X, Feuerstein GZ (1998) Ischemic preconditioning and brain tolerance: temporal histological and functional outcomes, protein synthesis requirement, and interleukin-1 receptor antagonist and early gene expression. Stroke 29:1937-1950; discussion 1950-1931
    • (1998) Stroke , vol.29 , pp. 1937-1950
    • Barone, F.C.1    White, R.F.2    Spera, P.A.3    Ellison, J.4    Currie, R.W.5    Wang, X.6    Feuerstein, G.Z.7
  • 5
    • 0030818468 scopus 로고    scopus 로고
    • Ischemic preconditioning of myocardium
    • Baxter GF (1997) Ischemic preconditioning of myocardium. Ann Med 29:345-352
    • (1997) Ann Med , vol.29 , pp. 345-352
    • Baxter, G.F.1
  • 6
    • 0037203344 scopus 로고    scopus 로고
    • Glucosylceramide synthase and apoptosis
    • Bleicher RJ, Cabot MC (2002) Glucosylceramide synthase and apoptosis. Biochim Biophys Acta 1585:172-178
    • (2002) Biochim Biophys Acta , vol.1585 , pp. 172-178
    • Bleicher, R.J.1    Cabot, M.C.2
  • 7
    • 0030066567 scopus 로고    scopus 로고
    • Ceramide induces apoptosis in cultured mesencephalic neurons
    • Brugg B, Michel PP, Agid Y, Ruberg M (1996) Ceramide induces apoptosis in cultured mesencephalic neurons. J Neurochem 66:733-739
    • (1996) J Neurochem , vol.66 , pp. 733-739
    • Brugg, B.1    Michel, P.P.2    Agid, Y.3    Ruberg, M.4
  • 8
    • 0031037347 scopus 로고    scopus 로고
    • Ischemic tolerance in the brain
    • Chen J, Simon R (1997) Ischemic tolerance in the brain. Neurology 48:306-311
    • (1997) Neurology , vol.48 , pp. 306-311
    • Chen, J.1    Simon, R.2
  • 9
    • 0035196451 scopus 로고    scopus 로고
    • The protective effect of ceramide in immature rat brain hypoxia-ischemia involves up-regulation of bcl-2 and reduction of TUNEL-positive cells
    • Chen Y, Ginis I, Hallenbeck JM (2001) The protective effect of ceramide in immature rat brain hypoxia-ischemia involves up-regulation of bcl-2 and reduction of TUNEL-positive cells. J Cereb Blood Flow Metab 21:34-40
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 34-40
    • Chen, Y.1    Ginis, I.2    Hallenbeck, J.M.3
  • 10
    • 0034724792 scopus 로고    scopus 로고
    • Benign focal ischemic preconditioning induces neuronal Hsp70 and prolonged astrogliosis with expression of Hsp27
    • Currie RW, Ellison JA, White RF, Feuerstein GZ, Wang X, Barone FC (2000) Benign focal ischemic preconditioning induces neuronal Hsp70 and prolonged astrogliosis with expression of Hsp27. Brain Res 863:169-181
    • (2000) Brain Res , vol.863 , pp. 169-181
    • Currie, R.W.1    Ellison, J.A.2    White, R.F.3    Feuerstein, G.Z.4    Wang, X.5    Barone, F.C.6
  • 11
  • 12
    • 0035092459 scopus 로고    scopus 로고
    • Cell permeable exogenous ceramide reduces infarct size in spontaneously hypertensive rats supporting in vitro studies that have implicated ceramide in induction of tolerance to ischemia
    • Furuya K, Ginis I, Takeda H, Chen Y, Hallenbeck JM (2001) Cell permeable exogenous ceramide reduces infarct size in spontaneously hypertensive rats supporting in vitro studies that have implicated ceramide in induction of tolerance to ischemia. J Cereb Blood Flow Metab 21:226-232
    • (2001) J Cereb Blood Flow Metab , vol.21 , pp. 226-232
    • Furuya, K.1    Ginis, I.2    Takeda, H.3    Chen, Y.4    Hallenbeck, J.M.5
  • 13
    • 0031866963 scopus 로고    scopus 로고
    • Ceramide and its interconvertible metabolite sphingosine function as indispensable lipid factors involved in survival and dendritic differentiation of cerebellar Purkinje cells
    • Furuya S, Mitoma J, Makino A, Hirabayashi Y (1998) Ceramide and its interconvertible metabolite sphingosine function as indispensable lipid factors involved in survival and dendritic differentiation of cerebellar Purkinje cells. J Neurochem 71:366-377
    • (1998) J Neurochem , vol.71 , pp. 366-377
    • Furuya, S.1    Mitoma, J.2    Makino, A.3    Hirabayashi, Y.4
  • 14
    • 0033017265 scopus 로고    scopus 로고
    • TNF-alpha pretreatment prevents subsequent activation of cultured brain cells with TNF-alpha and hypoxia via ceramide
    • Ginis I, Schweizer U, Brenner M, Liu J, Azzam N, Spatz M, Hallenbeck JM (1999) TNF-alpha pretreatment prevents subsequent activation of cultured brain cells with TNF-alpha and hypoxia via ceramide. Am J Physiol 276:C1171-1193
    • (1999) Am J Physiol , vol.276
    • Ginis, I.1    Schweizer, U.2    Brenner, M.3    Liu, J.4    Azzam, N.5    Spatz, M.6    Hallenbeck, J.M.7
  • 15
    • 0030026613 scopus 로고    scopus 로고
    • Ceramide protects hippocampal neurons against excitotoxic and oxidative insults, and amyloid beta-peptide toxicity
    • Goodman Y, Mattson MP (1996) Ceramide protects hippocampal neurons against excitotoxic and oxidative insults, and amyloid beta-peptide toxicity. J Neurochem 66:869-872
    • (1996) J Neurochem , vol.66 , pp. 869-872
    • Goodman, Y.1    Mattson, M.P.2
  • 16
    • 0034656034 scopus 로고    scopus 로고
    • Does ceramide play a role in neural cell apoptosis?
    • Goswami R, Dawson G (2000) Does ceramide play a role in neural cell apoptosis? J Neurosci Res 60:141-149
    • (2000) J Neurosci Res , vol.60 , pp. 141-149
    • Goswami, R.1    Dawson, G.2
  • 17
    • 0030448021 scopus 로고    scopus 로고
    • Functions of ceramide in coordinating cellular responses to stress
    • Hannun YA (1996) Functions of ceramide in coordinating cellular responses to stress. Science 274:1855-1859
    • (1996) Science , vol.274 , pp. 1855-1859
    • Hannun, Y.A.1
  • 18
    • 0033974782 scopus 로고    scopus 로고
    • Ceramide in the eukaryotic stress response
    • Hannun YA, Luberto C (2000) Ceramide in the eukaryotic stress response. Trends Cell Biol 10:73-80
    • (2000) Trends Cell Biol , vol.10 , pp. 73-80
    • Hannun, Y.A.1    Luberto, C.2
  • 19
    • 0032714497 scopus 로고    scopus 로고
    • Tumor necrosis factor-alpha, sphingosine, ceramide: Which is the appropriate marker of inflammation?
    • Horton JW (1999) Tumor necrosis factor-alpha, sphingosine, ceramide: which is the appropriate marker of inflammation? Crit Care Med 27:2580-2581
    • (1999) Crit Care Med , vol.27 , pp. 2580-2581
    • Horton, J.W.1
  • 20
    • 0032080795 scopus 로고    scopus 로고
    • Glucosylceramide synthase and glycosphingolipid synthesis
    • Ichikawa S, Hirabayashi Y (1998) Glucosylceramide synthase and glycosphingolipid synthesis. Trends Cell Biol 8:198-202
    • (1998) Trends Cell Biol , vol.8 , pp. 198-202
    • Ichikawa, S.1    Hirabayashi, Y.2
  • 21
    • 0032246119 scopus 로고    scopus 로고
    • L-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol stimulates ganglioside biosynthesis, neurite outgrowth and synapse formation in cultured cortical neurons, and ameliorates memory deficits in ischemic rats
    • Inokuchi J, Kuroda Y, Kosaka S, Fujiwara M (1998) L-threo-1-phenyl-2-decanoylamino-3-morpholino-1-propanol stimulates ganglioside biosynthesis, neurite outgrowth and synapse formation in cultured cortical neurons, and ameliorates memory deficits in ischemic rats. Acta Biochim Pol 45:479-492
    • (1998) Acta Biochim Pol , vol.45 , pp. 479-492
    • Inokuchi, J.1    Kuroda, Y.2    Kosaka, S.3    Fujiwara, M.4
  • 22
    • 0029049833 scopus 로고
    • Ceramide prevents neuronal programmed cell death induced by nerve growth factor deprivation
    • Ito A, Horigome K (1995) Ceramide prevents neuronal programmed cell death induced by nerve growth factor deprivation. J Neurochem 65:463-466
    • (1995) J Neurochem , vol.65 , pp. 463-466
    • Ito, A.1    Horigome, K.2
  • 25
    • 0033605719 scopus 로고    scopus 로고
    • Regulation of intracellular ceramide content in B16 melanoma cells. Biological implications of ceramide glycosylation
    • Komori H, Ichikawa S, Hirabayashi Y, Ito M (1999) Regulation of intracellular ceramide content in B16 melanoma cells. Biological implications of ceramide glycosylation. J Biol Chem 274:8981-8987
    • (1999) J Biol Chem , vol.274 , pp. 8981-8987
    • Komori, H.1    Ichikawa, S.2    Hirabayashi, Y.3    Ito, M.4
  • 26
    • 0034705815 scopus 로고    scopus 로고
    • Regulation of UDP-glucose:ceramide glucosyltransferase-1 by ceramide
    • Komori H, Ichikawa S, Hirabayashi Y, Ito M (2000) Regulation of UDP-glucose:ceramide glucosyltransferase-1 by ceramide. FEBS Lett 475:247-250
    • (2000) FEBS Lett , vol.475 , pp. 247-250
    • Komori, H.1    Ichikawa, S.2    Hirabayashi, Y.3    Ito, M.4
  • 29
    • 0033976146 scopus 로고    scopus 로고
    • Hypoxic preconditioning protects cultured neurons against hypoxic stress via TNF-alpha and ceramide
    • Liu J, Ginis I, Spatz M, Hallenbeck JM (2000) Hypoxic preconditioning protects cultured neurons against hypoxic stress via TNF-alpha and ceramide. Am J Physiol Cell Physiol 278:C144-C153
    • (2000) Am J Physiol Cell Physiol , vol.278
    • Liu, J.1    Ginis, I.2    Spatz, M.3    Hallenbeck, J.M.4
  • 30
    • 0035079539 scopus 로고    scopus 로고
    • Ceramide glycosylation potentiates cellular multidrug resistance
    • Liu YY, Han TY, Giuliano AE, Cabot MC (2001) Ceramide glycosylation potentiates cellular multidrug resistance. FASEB J 15:719-730
    • (2001) FASEB J , vol.15 , pp. 719-730
    • Liu, Y.Y.1    Han, T.Y.2    Giuliano, A.E.3    Cabot, M.C.4
  • 31
    • 0033231485 scopus 로고    scopus 로고
    • Glycosylation of ceramide potentiates cellular resistance to tumor necrosis factor-alpha-induced apoptosis
    • Liu YY, Han TY, Giuliano AE, Ichikawa S, Hirabayashi Y, Cabot MC (1999) Glycosylation of ceramide potentiates cellular resistance to tumor necrosis factor-alpha-induced apoptosis. Exp Cell Res 252:464-470
    • (1999) Exp Cell Res , vol.252 , pp. 464-470
    • Liu, Y.Y.1    Han, T.Y.2    Giuliano, A.E.3    Ichikawa, S.4    Hirabayashi, Y.5    Cabot, M.C.6
  • 32
    • 0036695392 scopus 로고    scopus 로고
    • Ceramide regulation of apoptosis versus differentiation: A walk on a fine line. Lessons from neurobiology
    • Luberto C, Kraveka JM, Hannun YA (2002) Ceramide regulation of apoptosis versus differentiation: a walk on a fine line. Lessons from neurobiology. Neurochem Res 27:609-617
    • (2002) Neurochem Res , vol.27 , pp. 609-617
    • Luberto, C.1    Kraveka, J.M.2    Hannun, Y.A.3
  • 36
    • 0032520898 scopus 로고    scopus 로고
    • Bipotential roles of ceramide in the growth of hippocampal neurons: Promotion of cell survival and dendritic outgrowth in dose- and developmental stage-dependent manners
    • Mitoma J, Ito M, Furuya S, Hirabayashi Y (1998) Bipotential roles of ceramide in the growth of hippocampal neurons: promotion of cell survival and dendritic outgrowth in dose- and developmental stage-dependent manners. J Neurosci Res 51:712-722
    • (1998) J Neurosci Res , vol.51 , pp. 712-722
    • Mitoma, J.1    Ito, M.2    Furuya, S.3    Hirabayashi, Y.4
  • 37
    • 0022970945 scopus 로고
    • Preconditioning with ischemia: A delay of lethal cell injury in ischemic myocardium
    • Murry CE, Jennings RB, Reimer KA (1986) Preconditioning with ischemia: a delay of lethal cell injury in ischemic myocardium. Circulation 74:1124-1136
    • (1986) Circulation , vol.74 , pp. 1124-1136
    • Murry, C.E.1    Jennings, R.B.2    Reimer, K.A.3
  • 38
    • 0034704409 scopus 로고    scopus 로고
    • Lethal forebrain ischemia stimulates sphingo-myelin hydrolysis and ceramide generation in the gerbil hippocampus
    • Nakane M, Kubota M, Nakagomi T, Tamura A, Hisaki H, Shimasaki H, Ueta N (2000) Lethal forebrain ischemia stimulates sphingo-myelin hydrolysis and ceramide generation in the gerbil hippocampus. Neurosci Lett 296:89-92
    • (2000) Neurosci Lett , vol.296 , pp. 89-92
    • Nakane, M.1    Kubota, M.2    Nakagomi, T.3    Tamura, A.4    Hisaki, H.5    Shimasaki, H.6    Ueta, N.7
  • 39
    • 0031005797 scopus 로고    scopus 로고
    • TNF-alpha pretreatment induces protective effects against focal cerebral ischemia in mice
    • Nawashiro H, Tasaki K, Ruetzler CA, Hallenbeck JM (1997) TNF-alpha pretreatment induces protective effects against focal cerebral ischemia in mice. J Cereb Blood Flow Metab 17:483-490
    • (1997) J Cereb Blood Flow Metab , vol.17 , pp. 483-490
    • Nawashiro, H.1    Tasaki, K.2    Ruetzler, C.A.3    Hallenbeck, J.M.4
  • 40
    • 0029974018 scopus 로고    scopus 로고
    • Interleukin-1 mediates induction of tolerance to global ischemia in gerbil hippocampal CA1 neurons
    • Ohtsuki T, Ruetzler CA, Tasaki K, Hallenbeck JM (1996) Interleukin-1 mediates induction of tolerance to global ischemia in gerbil hippocampal CA1 neurons. J Cereb Blood Flow Metab 16:1137-1142
    • (1996) J Cereb Blood Flow Metab , vol.16 , pp. 1137-1142
    • Ohtsuki, T.1    Ruetzler, C.A.2    Tasaki, K.3    Hallenbeck, J.M.4
  • 41
    • 0037203342 scopus 로고    scopus 로고
    • Ceramide in apoptosis: An overview and current perspectives
    • Pettus BJ, Chalfant CE, Hannun YA (2002) Ceramide in apoptosis: an overview and current perspectives. Biochim Biophys Acta 1585:114-125
    • (2002) Biochim Biophys Acta , vol.1585 , pp. 114-125
    • Pettus, B.J.1    Chalfant, C.E.2    Hannun, Y.A.3
  • 42
    • 0037457360 scopus 로고    scopus 로고
    • Strain-dependent response to cerebral ischemic preconditioning: Differences between spontaneously hypertensive and stroke prone spontaneously hypertensive rats
    • Purcell JE, Lenhard SC, White RF, Schaeffer T, Barone FC, Chandra S (2003) Strain-dependent response to cerebral ischemic preconditioning: differences between spontaneously hypertensive and stroke prone spontaneously hypertensive rats. Neurosci Lett 339:151-155
    • (2003) Neurosci Lett , vol.339 , pp. 151-155
    • Purcell, J.E.1    Lenhard, S.C.2    White, R.F.3    Schaeffer, T.4    Barone, F.C.5    Chandra, S.6
  • 43
    • 0028274832 scopus 로고
    • Glucosylceramide in the nervous system: A mini-review
    • Radin NS (1994) Glucosylceramide in the nervous system: a mini-review. Neurochem Res 19:533-540
    • (1994) Neurochem Res , vol.19 , pp. 533-540
    • Radin, N.S.1
  • 44
    • 0031059654 scopus 로고    scopus 로고
    • Lipopolysaccharide pre-treatment induces resistance against subsequent focal cerebral ischemic damage in spontaneously hypertensive rats
    • Tasaki K, Ruetzler CA, Ohtsuki T, Martin D, Nawashiro H, Hallenbeck JM (1997) Lipopolysaccharide pre-treatment induces resistance against subsequent focal cerebral ischemic damage in spontaneously hypertensive rats. Brain Res 748:267-270
    • (1997) Brain Res , vol.748 , pp. 267-270
    • Tasaki, K.1    Ruetzler, C.A.2    Ohtsuki, T.3    Martin, D.4    Nawashiro, H.5    Hallenbeck, J.M.6
  • 45
    • 0036570037 scopus 로고    scopus 로고
    • Ceramide-induced cell death in primary neuronal cultures: Upregulation of ceramide levels during neuronal apoptosis
    • Toman RE, Movsesyan V, Murthy SK, Milstien S, Spiegel S, Faden AI (2002) Ceramide-induced cell death in primary neuronal cultures: upregulation of ceramide levels during neuronal apoptosis. J Neurosci Res 68:323-330
    • (2002) J Neurosci Res , vol.68 , pp. 323-330
    • Toman, R.E.1    Movsesyan, V.2    Murthy, S.K.3    Milstien, S.4    Spiegel, S.5    Faden, A.I.6
  • 46
    • 0031794023 scopus 로고    scopus 로고
    • Use of suppression subtractive hybridization strategy for discovery of increased tissue inhibitor of matrix metalloproteinase-1 gene expression in brain ischemic tolerance
    • Wang X, Yaish-Ohad S, Li X, Barone FC, Feuerstein GZ (1998) Use of suppression subtractive hybridization strategy for discovery of increased tissue inhibitor of matrix metalloproteinase-1 gene expression in brain ischemic tolerance. J Cereb Blood Flow Metab 18:1173-1177
    • (1998) J Cereb Blood Flow Metab , vol.18 , pp. 1173-1177
    • Wang, X.1    Yaish-Ohad, S.2    Li, X.3    Barone, F.C.4    Feuerstein, G.Z.5
  • 47
    • 0034948731 scopus 로고    scopus 로고
    • Ceramide-induced apoptosis in cortical neurons is mediated by an increase in p38 phosphorylation and not by the decrease in ERK phosphorylation
    • Willaime S, Vanhoutte P, Caboche J, Lemaigre-Dubreuil Y, Mariani J, Brugg B (2001) Ceramide-induced apoptosis in cortical neurons is mediated by an increase in p38 phosphorylation and not by the decrease in ERK phosphorylation. Eur J Neurosci 13:2037-2046
    • (2001) Eur J Neurosci , vol.13 , pp. 2037-2046
    • Willaime, S.1    Vanhoutte, P.2    Caboche, J.3    Lemaigre-Dubreuil, Y.4    Mariani, J.5    Brugg, B.6
  • 48
    • 0035937488 scopus 로고    scopus 로고
    • Lipopolysaccharide-induced ischemic tolerance is associated with increased levels of ceramide in brain and in plasma
    • Zimmermann C, Ginis I, Furuya K, Klimanis D, Ruetzler C, Spatz M, Hallenbeck JM (2001) Lipopolysaccharide-induced ischemic tolerance is associated with increased levels of ceramide in brain and in plasma. Brain Res 895:59-65
    • (2001) Brain Res , vol.895 , pp. 59-65
    • Zimmermann, C.1    Ginis, I.2    Furuya, K.3    Klimanis, D.4    Ruetzler, C.5    Spatz, M.6    Hallenbeck, J.M.7


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.