Characterization of ceramide synthase 2: Tissue distribution, substrate specificity, and inhibition by sphingosine 1-phosphate

Journal of Biological Chemistry

Volumn 283, Issue 9, 2008, Pages 5677-5684

  Laviad, Elad L ^a   Albee, Lee ^a   Pankova Kholmyansky, Irene ^a   Epstein, Sharon ^a   Park, Hyejung ^b   Merrill Jr , Alfred H ^b   Futerman, Anthony H ^a  

^a WEIZMANN INSTITUTE OF SCIENCE   (Israel)

^b GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL CHAIN LENGTHS; ACYL CHAINS; BIO-CHEMICALS; CERAMIDE; CERAMIDE SYNTHASE; CERAMIDES; IN CELLS; KEY INTERMEDIATES; MRNA LEVELS; SIGNALING MOLECULES; SIGNALING PATHWAYS; SPHINGOLIPID; SPHINGOLIPID METABOLISMS; SPHINGOLIPIDS; SPHINGOMYELIN; SPHINGOSINE; SUBSTRATE SPECIFICITIES; SYNTHASES; TISSUE DISTRIBUTIONS;

BIOCHEMICAL ENGINEERING; BIOCHEMISTRY; CYTOLOGY; ENZYMES; FATTY ACIDS; LIPIDS; MAMMALS; PHYSIOLOGY;

AMIDES;

ACYL COENZYME A; CERAMIDE; MESSENGER RNA; SPHINGOLIPID; SPHINGOMYELIN; SPHINGOSINE 1 PHOSPHATE; SPHINGOSINE 1 PHOSPHATE RECEPTOR; SPHINGOSINE ACYLTRANSFERASE; DIHYDROCERAMIDE DESATURASE; DRUG DERIVATIVE; LYSOPHOSPHOLIPID; OXIDOREDUCTASE; SPHINGOSINE; SPHINGOSINE 1-PHOSPHATE; UNCLASSIFIED DRUG;

ARTICLE; CONTROLLED STUDY; CORRELATION ANALYSIS; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME INHIBITION; ENZYME SPECIFICITY; HUMAN; HUMAN CELL; LIPID METABOLISM; NONHUMAN; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; QUANTITATIVE ANALYSIS; SIGNAL TRANSDUCTION; SYNTHESIS; TISSUE DISTRIBUTION; ANIMAL; ANTIBODY SPECIFICITY; BIOSYNTHESIS; CELL LINE; DRUG ANTAGONISM; GENE EXPRESSION REGULATION; GENETICS; METABOLISM; MOUSE; PHYSIOLOGY;

MAMMALIA;

ANIMALS; CELL LINE; CERAMIDES; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HUMANS; LIPID METABOLISM; LYSOPHOSPHOLIPIDS; MICE; ORGAN SPECIFICITY; OXIDOREDUCTASES; RNA, MESSENGER; SIGNAL TRANSDUCTION; SPHINGOLIPIDS; SPHINGOSINE; SUBSTRATE SPECIFICITY;

EID: 41949140023     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M707386200     Document Type: Article

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