Developmentally regulated ceramide synthase 6 increases mitochondrial Ca2+ loading capacity and promotes apoptosis

Journal of Biological Chemistry

Volumn 286, Issue 6, 2011, Pages 4644-4658

  Novgorodov, Sergei A ^b   Chudakova, Daria A ^b   Wheeler, Brian W ^b   Bielawski, Jacek ^b   Kindy, Mark S ^b   Obeid, Lina M ^a,b   Gudz, Tatyana I ^a,b  

^a RALPH H JOHNSON VA MEDICAL CENTER   (United States)

^b MEDICAL UNIVERSITY OF SOUTH CAROLINA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

APOPTOSIS; APOPTOTIC; APOPTOTIC CELL DEATH; BRAIN DEVELOPMENT; CALPAIN ACTIVATION; CALPAINS; CELL SURVIVAL; CERAMIDE SYNTHASE; CERAMIDES; DOWN-REGULATION; FUMONISIN B1; IMMUNOPRECIPITATIONS; INNER MEMBRANES; LOADING CAPACITIES; MITOCHONDRIAL MATRIX; MITOCHONDRIAL PERMEABILITY TRANSITION PORE; MYRIOCIN; NERVE GROWTH FACTOR; OLIGODENDROCYTES; PRECURSOR CELLS; SPECIFIC INHIBITORS; SPHINGOLIPIDS; SPHINGOMYELIN; SPHINGOSINE; STRESS RESPONSE; SYNTHASES;

BIOCHEMISTRY; CALCIUM; CELL DEATH; MITOCHONDRIA;

AMIDES;

CALCIUM ION; CERAMIDE; CERAMIDE SYNTHASE 6; FUMONISIN B1; SMALL INTERFERING RNA; SPHINGOMYELIN; SPHINGOSINE; SPHINGOSINE ACYLTRANSFERASE; SYNTHETASE; THERMOZYMOCIDIN; UNCLASSIFIED DRUG; CALCIUM; CALPAIN; MITOCHONDRIAL PROTEIN; NERVE PROTEIN;

ANIMAL CELL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BRAIN DEVELOPMENT; BRAIN MITOCHONDRION; CALCIUM TRANSPORT; CELL SURVIVAL; CONTROLLED STUDY; DEVELOPMENTAL STAGE; DOWN REGULATION; ENZYME ACTIVITY; ENZYME REGULATION; FEMALE; LIPID BRAIN LEVEL; LIPOGENESIS; MEMBRANE COMPONENT; MITOCHONDRIAL PERMEABILITY; NEWBORN; NONHUMAN; OLIGODENDROGLIA; POROSITY; POSTNATAL DEVELOPMENT; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; ANIMAL; BRAIN; CELL CULTURE; CYTOLOGY; ENZYMOLOGY; GENE SILENCING; GENETICS; GROWTH, DEVELOPMENT AND AGING; HOMEOSTASIS; METABOLISM; MITOCHONDRION; PHYSIOLOGY; SPRAGUE DAWLEY RAT; STEM CELL;

ANIMALS; APOPTOSIS; BRAIN; CALCIUM; CALPAIN; CELLS, CULTURED; FEMALE; GENE KNOCKDOWN TECHNIQUES; HOMEOSTASIS; MITOCHONDRIA; MITOCHONDRIAL PROTEINS; NERVE TISSUE PROTEINS; OLIGODENDROGLIA; RATS; RATS, SPRAGUE-DAWLEY; SPHINGOSINE N-ACYLTRANSFERASE; STEM CELLS;

EID: 79953018812     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.164392     Document Type: Article

References (79)

1. Hannun, Y. A., and Obeid, L. M. (2008) Nat. Rev. Mol. Cell Biol. 9, 139-150
2. Kolesnick, R. N., Goñi, F. M., and Alonso, A. (2000) J. Cell. Physiol. 184, 285-300
3. Futerman, A. H., and Riezman, H. (2005) Trends Cell Biol. 15, 312-318
4. Merrill, A. H., Jr. (2002) J. Biol. Chem. 277, 25843-25846
5. Mandon, E. C., Ehses, I., Rother, J., van Echten, G., and Sandhoff, K. (1992) J. Biol. Chem. 267, 11144-11148
6. Kolter, T., Proia, R. L., and Sandhoff, K. (2002) J. Biol. Chem. 277, 25859-25862
7. Futerman, A. H., Stieger, B., Hubbard, A. L., and Pagano, R. E. (1990) J. Biol. Chem. 265, 8650-8657
8. Novgorodov, S. A., and Gudz, T. I. (2009) J. Cardiovasc. Pharmacol. 53, 198-208
9. El Bawab, S., Roddy, P., Qian, T., Bielawska, A., Lemasters, J. J., and Hannun, Y. A. (2000) J. Biol. Chem. 275, 21508-21513
10. Wu, B. X., Rajagopalan, V., Roddy, P. L., Clarke, C. J., and Hannun, Y. A. (2010) J. Biol. Chem. 285, 17993-18002
11. Bionda, C., Portoukalian, J., Schmitt, D., Rodriguez-Lafrasse, C., and Ardail, D. (2004) Biochem. J. 382, 527-533
12. Yu, J., Novgorodov, S. A., Chudakova, D., Zhu, H., Bielawska, A., Bielawski, J., Obeid, L. M., Kindy, M. S., and Gudz, T. I. (2007) J. Biol. Chem. 282, 25940-25949
13. Deng, X., Yin, X., Allan, R., Lu, D. D., Maurer, C. W., Haimovitz-Friedman, A., Fuks, Z., Shaham, S., and Kolesnick, R. (2008) Science 322, 110-115
14. Mizutani, Y., Kihara, A., and Igarashi, Y. (2005) Biochem. J. 390, 263-271
15. Spassieva, S., Seo, J. G., Jiang, J. C., Bielawski, J., Alvarez-Vasquez, F., Jazwinski, S. M., Hannun, Y. A., and Obeid, L. M. (2006) J. Biol. Chem. 281, 33931-33938
16. Mizutani, Y., Kihara, A., and Igarashi, Y. (2006) Biochem. J. 398, 531-538
17. Laviad, E. L., Albee, L., Pankova-Kholmyansky, I., Epstein, S., Park, H., Merrill, A. H., Jr., and Futerman, A. H. (2008) J. Biol. Chem. 283, 5677-5684
18. Lahiri, S., and Futerman, A. H. (2005) J. Biol. Chem. 280, 33735-33738
19. Novgorodov, S. A., Gudz, T. I., Milgrom, Y. M., and Brierley, G. P. (1992) J. Biol. Chem. 267, 16274-16282
20. Chudakova, D. A., Zeidan, Y. H., Wheeler, B. W., Yu, J., Novgorodov, S. A., Kindy, M. S., Hannun, Y. A., and Gudz, T. I. (2008) J. Biol. Chem. 283, 28806-28816
21. Bielawski, J., Szulc, Z. M., Hannun, Y. A., and Bielawska, A. (2006) Methods 39, 82-91
22. Hannun, Y. A., and Obeid, L. M. (2002) J. Biol. Chem. 277, 25847-25850
23. van Meer, G. (2005) EMBO J. 24, 3159-3165
24. Degroote, S., Wolthoorn, J., and van Meer, G. (2004) Semin. Cell Dev. Biol. 15, 375-387
25. Futerman, A. H. (2006) Biochim. Biophys. Acta 1758, 1885-1892
26. Nicholls, D. G. (1985) Prog. Brain Res. 63, 97-106
27. Chalmers, S., and Nicholls, D. G. (2003) J. Biol. Chem. 278, 19062-19070
28. Kristian, T., Pivovarova, N. B., Fiskum, G., and Andrews, S. B. (2007) J. Neurochem. 102, 1346-1356
29. Kirichok, Y., Krapivinsky, G., and Clapham, D. E. (2004) Nature 427, 360-364
30. Hoppe, U. C. (2010) FEBS Lett. 584, 1975-1981
31. Novgorodov, S. A., and Gudz, T. I. (1996) J. Bioenerg. Biomembr. 28, 139-146
32. Brustovetsky, N., and Dubinsky, J. M. (2000) J. Neurosci. 20, 8229-8237
33. Brustovetsky, N., and Dubinsky, J. M. (2000) J. Neurosci. 20, 103-113
34. Kushnareva, Y. E., Wiley, S. E., Ward, M. W., Andreyev, A. Y., and Murphy, A. N. (2005) J. Biol. Chem. 280, 28894-28902
35. Novgorodov, S. A., Gudz, T. I., and Obeid, L. M. (2008) J. Biol. Chem. 283, 24707-24717
36. Barres, B. A., Hart, I. K., Coles, H. S., Burne, J. F., Voyvodic, J. T., Richardson, W. D., and Raff, M. C. (1992) Cell 70, 31-46
37. Gudz, T. I., Komuro, H., and Macklin, W. B. (2006) J. Neuros ci. 26, 2458-2466
38. Matute, C., Domercq, M., and Sánchez-Gómez, M. V. (2006) Glia 53, 212-224
39. Goldberg, M. P., and Ransom, B. R. (2003) Stroke 34, 330-332
40. Wang, L., Hinoi, E., Takemori, A., Nakamichi, N., and Yoneda, Y. (2006) J. Biol. Chem. 281, 24553-24565
41. Iemata, M., Takarada, T., Hinoi, E., Taniura, H., and Yoneda, Y. (2007) J. Cell. Physiol. 213, 721-729
42. Kitatani, K., Idkowiak-Baldys, J., and Hannun, Y. A. (2008) Cell Signal. 20, 1010-1018
43. Cosgaya, J. M., Chan, J. R., and Shooter, E. M. (2002) Science 298, 1245-1248
44. Casaccia-Bonnefil, P., Carter, B. D., Dobrowsky, R. T., and Chao, M. V. (1996) Nature 383, 716-719
45. Harrington, A. W., Kim, J. Y., and Yoon, S. O. (2002) J. Neurosci. 22, 156-166
46. Gu, C., Casaccia-Bonnefil, P., Srinivasan, A., and Chao, M. V. (1999) J. Neurosci. 19, 3043-3049
47. Kar, P., Chakraborti, T., Samanta, K., and Chakraborti, S. (2008) Arch. Biochem. Biophys. 470, 176-186
48. Ozaki, T., Yamashita, T., and Ishiguro, S. (2009) Biochim. Biophys. Acta 1793, 1848-1859
49. Arrington, D. D., Van Vleet, T. R., and Schnellmann, R. G. (2006) Am. J. Physiol. Cell Physiol. 291, C1159-1171
50. Elce, J. S., Hegadorn, C., and Arthur, J. S. (1997) J. Biol. Chem. 272, 11268-11275
51. Kar, P., Samanta, K., Shaikh, S., Chowdhury, A., Chakraborti, T., and Chakraborti, S. (2010) Arch. Biochem. Biophys. 495, 1-7
52. Tsujinaka, T., Kajiwara, Y., Kambayashi, J., Sakon, M., Higuchi, N., Tanaka, T., and Mori, T. (1988) Biochem. Biophys. Res. Commun. 153, 1201-1208
53. Lampi, K. J., Kadoya, K., Azuma, M., David, L. L., and Shearer, T. R. (1992) Toxicol. Appl. Pharmacol. 117, 53-57
54. Wang, K. K., Nath, R., Posner, A., Raser, K. J., Buroker-Kilgore, M., Hajimohammadreza, I., Probert, A. W., Jr., Marcoux, F. W., Ye, Q., Takano, E., Hatanaka, M., Maki, M., Caner, H., Collins, J. L., Fergus, A., Lee, K. S., Lunney, E. A., Hays, S. J., and Yuen, P. (1996) Proc. Natl. Acad. Sci. U.S.A. 93, 6687-6692
55. Das, A., Sribnick, E. A., Wingrave, J. M., Del Re, A. M., Woodward, J. J., Appel, S. H., Banik, N. L., and Ray, S. K. (2005) J. Neurosci. Res. 81, 551-562
56. Meier, P., Finch, A., and Evan, G. (2000) Nature 407, 796-801
57. de la Rosa, E. J., and de Pablo, F. (2000) Trends Neurosci. 23, 454-458
58. Barres, B. A., and Raff, M. C. (1999) J. Cell Biol. 147, 1123-1128
59. Lakhani, S. A., Masud, A., Kuida, K., Porter, G. A., Jr., Booth, C. J., Mehal, W. Z., Inayat, I., and Flavell, R. A. (2006) Science 311, 847-851
60. Brann, A. B., Scott, R., Neuberger, Y., Abulafia, D., Boldin, S., Fainzilber, M., and Futerman, A. H. (1999) J. Neurosci. 19, 8199-8206
61. Blöchl, A., and Blöchl, R. (2007) J. Neurochem. 102, 289-305
62. Grassmé, H., Cremesti, A., Kolesnick, R., and Gulbins, E. (2003) Oncogene 22, 5457-5470
63. van Blitterswijk, W. J., van der Luit, A. H., Veldman, R. J., Verheij, M., and Borst, J. (2003) Biochem. J. 369, 199-211
64. Ardail, D., Popa, I., Alcantara, K., Pons, A., Zanetta, J. P., Louisot, P., Thomas, L., and Portoukalian, J. (2001) FEBS Lett. 488, 160-164
65. Tserng, K. Y., and Griffin, R. (2003) Anal. Biochem. 323, 84-93
66. Morell, P., and Radin, N. S. (1970) J. Biol. Chem. 245, 342-350
67. Ullman, M. D., and Radin, N. S. (1972) Arch. Biochem. Biophys. 152, 767-777
68. Shimeno, H., Soeda, S., Yasukouchi, M., Okamura, N., and Nagamatsu, A. (1995) Biol. Pharm. Bull. 18, 1335-1339
69. Shimeno, H., Soeda, S., Sakamoto, M., Kouchi, T., Kowakame, T., and Kihara, T. (1998) Lipids 33, 601-605
70. Csordás, G., and Hajnóczky, G. (2009) Biochim. Biophys. Acta 1787, 1352-1362
71. El Bawab, S., Birbes, H., Roddy, P., Szulc, Z. M., Bielawska, A., and Hannun, Y. A. (2001) J. Biol. Chem. 276, 16758-16766
72. Wooten-Blanks, L. G., Song, P., Senkal, C. E., and Ogretmen, B. (2007) FASEB J. 21, 3386-3397
73. Kitatani, K., Idkowiak-Baldys, J., Bielawski, J., Taha, T. A., Jenkins, R. W., Senkal, C. E., Ogretmen, B., Obeid, L. M., and Hannun, Y. A. (2006) J. Biol. Chem. 281, 36793-36802
74. Noureddine, L., Azzam, R., Nemer, G., Bielawski, J., Nasser, M., Bitar, F., and Dbaibo, G. S. (2008) Prostaglandins Other Lipid Mediat. 86, 49-55
75. Sot, J., Aranda, F. J., Collado, M. I., Goñi, F. M., and Alonso, A. (2005) Biophys. J. 88, 3368-3380
76. Wang, X., Carlsson, Y., Basso, E., Zhu, C., Rousset, C. I., Rasola, A., Johansson, B. R., Blomgren, K., Mallard, C., Bernardi, P., Forte, M. A., and Hagberg, H. (2009) J. Neurosci. 29, 2588-2596
77. Potter, D. A., Tirnauer, J. S., Janssen, R., Croall, D. E., Hughes, C. N., Fiacco, K. A., Mier, J. W., Maki, M., and Herman, I. M. (1998) J. Cell Biol. 141, 647-662
78. Ishihara, I., Minami, Y., Nishizaki, T., Matsuoka, T., and Yamamura, H. (2000) Neurosci. Lett. 279, 97-100
79. Joshi, A., Bondada, V., and Geddes, J. W. (2009) Exp. Neurol. 218, 221-227