메뉴 건너뛰기




Volumn 13, Issue 1, 2012, Pages 17-26

Roles of connexins in atherosclerosis and ischemia-reperfusion injury

Author keywords

Atherosclerosis; Connexin; Gap junction; Hemichannels; Ischemia reperfusion; Preconditioning

Indexed keywords

AAP10 PEPTIDE; CONNEXIN 37; CONNEXIN 40; CONNEXIN 43; CONNEXIN 45; CONNEXON; GAP JUNCTION CHANNEL; GAP JUNCTION PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE P38; PEPTIDE; PROTEIN; ROTIGAPTIDE; RXP PEPTIDE; UNCLASSIFIED DRUG;

EID: 84855827472     PISSN: 13892010     EISSN: 18734316     Source Type: Journal    
DOI: 10.2174/138920112798868638     Document Type: Review
Times cited : (18)

References (145)
  • 1
    • 47149103242 scopus 로고    scopus 로고
    • Pre-conditioning and post conditioning to limit ischemia-reperfusion-induced myocardial injury: What could be the next footstep?
    • Balakumar, P.; Rohilla, A.; Singh, M. Pre-conditioning and post conditioning to limit ischemia-reperfusion-induced myocardial injury: what could be the next footstep? Pharmacol. Res., 2008, 57, 403-412.
    • (2008) Pharmacol. Res. , vol.57 , pp. 403-412
    • Balakumar, P.1    Rohilla, A.2    Singh, M.3
  • 3
    • 0037180771 scopus 로고    scopus 로고
    • Inflammation in atherosclerosis
    • Libby, P. Inflammation in atherosclerosis. Nature, 2002, 420, 868-874.
    • (2002) Nature , vol.420 , pp. 868-874
    • Libby, P.1
  • 4
    • 17644412023 scopus 로고    scopus 로고
    • Inflammation, atherosclerosis, and coronary artery disease
    • Hansson, G. K. Inflammation, atherosclerosis, and coronary artery disease. N. Engl. J. Med., 2005, 352, 1685-1695.
    • (2005) N. Engl. J. Med. , vol.352 , pp. 1685-1695
    • Hansson, G.K.1
  • 5
    • 0036872332 scopus 로고    scopus 로고
    • Interaction of connexins with protein partners in the control of channel turnover and gating
    • Thomas, M. A.; Huang, S.; Cokoja, A.; Riccio, O.; Staub, O.; Suter, S.; Chanson, M. Interaction of connexins with protein partners in the control of channel turnover and gating. Biol. Cell, 2002, 94, 445-456.
    • (2002) Biol. Cell , vol.94 , pp. 445-456
    • Thomas, M.A.1    Huang, S.2    Cokoja, A.3    Riccio, O.4    Staub, O.5    Suter, S.6    Chanson, M.7
  • 6
    • 0036556336 scopus 로고    scopus 로고
    • Formation of the gap junction nexus: Binding partners for connexins
    • Duffy, H. S.; Delmar, M.; Spray, D. C. Formation of the gap junction nexus: binding partners for connexins. J. Physiol. Paris, 2002, 96, 243-249.
    • (2002) J. Physiol. Paris , vol.96 , pp. 243-249
    • Duffy, H.S.1    Delmar, M.2    Spray, D.C.3
  • 7
    • 1942503184 scopus 로고    scopus 로고
    • Gap junctions and connexin-interacting proteins
    • Giepmans, B. N. Gap junctions and connexin-interacting proteins. Cardiovasc. Res., 2004, 62, 233-245.
    • (2004) Cardiovasc. Res. , vol.62 , pp. 233-245
    • Giepmans, B.N.1
  • 8
    • 34447526059 scopus 로고    scopus 로고
    • Connexin37: A potential modifier gene of inflammatory disease
    • Chanson, M.; Kwak, B. R. Connexin37: a potential modifier gene of inflammatory disease. J. Mol. Med., 2007, 85, 787-795.
    • (2007) J. Mol. Med. , vol.85 , pp. 787-795
    • Chanson, M.1    Kwak, B.R.2
  • 9
    • 1942438659 scopus 로고    scopus 로고
    • Incorporation of connexins into plasma membranes and gap junctions
    • Martin, P. E.; Evans, W. H. Incorporation of connexins into plasma membranes and gap junctions. Cardiovasc. Res., 2004, 62, 378-387.
    • (2004) Cardiovasc. Res. , vol.62 , pp. 378-387
    • Martin, P.E.1    Evans, W.H.2
  • 11
    • 0038819143 scopus 로고    scopus 로고
    • Nonredundant gap junction functions
    • White, T. W. Nonredundant gap junction functions, News Physiol. Sci., 2003, 18, 95-99.
    • (2003) News Physiol. Sci. , vol.18 , pp. 95-99
    • White, T.W.1
  • 12
    • 37349051401 scopus 로고    scopus 로고
    • Connexin45 cannot replace the function of connexin40 in conducting endothelium-dependent dilations along arterioles
    • Wolfle, S. E.; Schmidt, V. J.; Hoepfl, B.; Gebert, A.; Alcolea, S.; Gros, D.; de Wit, C. Connexin45 cannot replace the function of connexin40 in conducting endothelium-dependent dilations along arterioles. Circ. Res., 2007, 101, 1292-1299.
    • (2007) Circ. Res. , vol.101 , pp. 1292-1299
    • Wolfle, S.E.1    Schmidt, V.J.2    Hoepfl, B.3    Gebert, A.4    Alcolea, S.5    Gros, D.6    de Wit, C.7
  • 13
    • 73349090269 scopus 로고    scopus 로고
    • Biological and biophysical properties of vascular connexin channels
    • Johnstone, S.; Isakson, B.; Locke, D. Biological and biophysical properties of vascular connexin channels. Int. Rev. Cell Mol. Biol., 2009, 278, 69-118.
    • (2009) Int. Rev. Cell Mol. Biol. , vol.278 , pp. 69-118
    • Johnstone, S.1    Isakson, B.2    Locke, D.3
  • 14
    • 0030028301 scopus 로고    scopus 로고
    • The gap junction communication channel
    • Kumar, N. M.; Gilula, N.B. The gap junction communication channel. Cell, 1996, 84, 381-388.
    • (1996) Cell , vol.84 , pp. 381-388
    • Kumar, N.M.1    Gilula, N.B.2
  • 15
    • 0347126503 scopus 로고    scopus 로고
    • An update on connexin genes and their nomenclature in mouse and man
    • Sohl, G.; Willecke, K. An update on connexin genes and their nomenclature in mouse and man. Cell Commun. Adhes, 2003, 10, 173-180.
    • (2003) Cell Commun. Adhes , vol.10 , pp. 173-180
    • Sohl, G.1    Willecke, K.2
  • 16
    • 17344390158 scopus 로고    scopus 로고
    • Plasma membrane channels formed by connexins: Their regulation and functions
    • Saez, J. C.; Berthoud, V. M.; Branes, M. C.; Martinez, A.D.; Beyer, E. C. Plasma membrane channels formed by connexins: their regulation and functions. Physiol. Rev., 2003, 83, 1359-1400.
    • (2003) Physiol. Rev. , vol.83 , pp. 1359-1400
    • Saez, J.C.1    Berthoud, V.M.2    Branes, M.C.3    Martinez, A.D.4    Beyer, E.C.5
  • 17
    • 0035754245 scopus 로고    scopus 로고
    • Role of cytoskeletal elements in the recruitment of Cx43-GFP and Cx26-YFP into gap junctions
    • Thomas, T.; Jordan, K.; Laird, D.W. Role of cytoskeletal elements in the recruitment of Cx43-GFP and Cx26-YFP into gap junctions. Cell Commun. Adhes., 2001, 8, 231-236.
    • (2001) Cell Commun. Adhes. , vol.8 , pp. 231-236
    • Thomas, T.1    Jordan, K.2    Laird, D.W.3
  • 19
    • 33645002735 scopus 로고    scopus 로고
    • Life cycle of connexins in health and disease
    • Laird, D.W. Life cycle of connexins in health and disease. Biochem J., 2006, 394, 527-543.
    • (2006) Biochem J. , vol.394 , pp. 527-543
    • Laird, D.W.1
  • 20
    • 0041831300 scopus 로고    scopus 로고
    • Gap junctional hemichannels in the heart
    • John, S.; Cesario, D.; Weiss, J.N. Gap junctional hemichannels in the heart. Acta Physiol Scand., 2003, 179, 23-31.
    • (2003) Acta Physiol Scand. , vol.179 , pp. 23-31
    • John, S.1    Cesario, D.2    Weiss, J.N.3
  • 22
    • 0037382614 scopus 로고    scopus 로고
    • Beyond the gap: Functions of unpaired connexon channels
    • Goodenough, D.A.; Paul, D.L. Beyond the gap: functions of unpaired connexon channels. Nat Rev. Mol. Cell Biol., 2003, 4, 285-294.
    • (2003) Nat Rev. Mol. Cell Biol. , vol.4 , pp. 285-294
    • Goodenough, D.A.1    Paul, D.L.2
  • 23
    • 0035991948 scopus 로고    scopus 로고
    • Gap junctions: Structure and function (Review)
    • Evans, W.H.; Martin, P.E. Gap junctions: structure and function (Review). Mol. Member Biol., 2002, 19, 121-136.
    • (2002) Mol. Member Biol. , vol.19 , pp. 121-136
    • Evans, W.H.1    Martin, P.E.2
  • 24
    • 0028940823 scopus 로고
    • Connexin 43 and connexin 40 gap junctional proteins are present in arteriolar smooth muscle and endothelium in vivo
    • Little, T.L.; Beyer, E.C.; Duling, B.R. Connexin 43 and connexin 40 gap junctional proteins are present in arteriolar smooth muscle and endothelium in vivo. Am. J. Physiol., 1995, 268, H729-739.
    • (1995) Am. J. Physiol. , vol.268
    • Little, T.L.1    Beyer, E.C.2    Duling, B.R.3
  • 26
    • 0032556026 scopus 로고    scopus 로고
    • Connexin43 is highly localized to sites of disturbed flow in rat aortic endothelium but connexin37 and connexin40 are more uniformly distributed
    • Gabriels, J.E.; Paul, D.L. Connexin43 is highly localized to sites of disturbed flow in rat aortic endothelium but connexin37 and connexin40 are more uniformly distributed. Circ. Res., 1998, 83, 636-643.
    • (1998) Circ. Res. , vol.83 , pp. 636-643
    • Gabriels, J.E.1    Paul, D.L.2
  • 27
    • 1942470625 scopus 로고    scopus 로고
    • Contribution of connexins to the function of the vascular wall
    • Haefliger, J.A.; Nicod, P.; Meda, P. Contribution of connexins to the function of the vascular wall. Cardiovasc. Res., 2004, 62, 345-356.
    • (2004) Cardiovasc. Res. , vol.62 , pp. 345-356
    • Haefliger, J.A.1    Nicod, P.2    Meda, P.3
  • 28
    • 30644473750 scopus 로고    scopus 로고
    • Endothelial mediators and communication through vascular gap junctions
    • de Wit, C.; Hoepfl, B.; Wolfle, S.E. Endothelial mediators and communication through vascular gap junctions. Biol. Chem., 2006, 387, 3-9.
    • (2006) Biol. Chem. , vol.387 , pp. 3-9
    • de Wit, C.1    Hoepfl, B.2    Wolfle, S.E.3
  • 30
    • 72049084553 scopus 로고    scopus 로고
    • Site-Specific Connexin Phosphorylation Is Associated with Reduced Heterocellular Communication between Smooth Muscle and Endothelium
    • Straub, A.C.; Johnstone, S.R.; Heberlein, K.R.; Rizzo, M.J.; Best, A.K.; Boitano, S.; Isakson, B. E. Site-Specific Connexin Phosphorylation Is Associated with Reduced Heterocellular Communication between Smooth Muscle and Endothelium. J. Vasc. Res., 2009, 47, 277-286.
    • (2009) J. Vasc. Res. , vol.47 , pp. 277-286
    • Straub, A.C.1    Johnstone, S.R.2    Heberlein, K.R.3    Rizzo, M.J.4    Best, A.K.5    Boitano, S.6    Isakson, B.E.7
  • 32
    • 33747855187 scopus 로고    scopus 로고
    • Novel aspects of endothelium-dependent regulation of vascular tone
    • Villar, I.C.; Francis, S.; Webb, A.; Hobbs, A.J.; Ahluwalia, A. Novel aspects of endothelium-dependent regulation of vascular tone. Kidney Int., 2006, 70, 840-853.
    • (2006) Kidney Int. , vol.70 , pp. 840-853
    • Villar, I.C.1    Francis, S.2    Webb, A.3    Hobbs, A.J.4    Ahluwalia, A.5
  • 33
    • 55949129040 scopus 로고    scopus 로고
    • Contribution of endothelium-derived hyperpolarizing factors to the regulation of vascular tone in humans
    • Bellien, J.; Thuillez, C.; Joannides, R. Contribution of endothelium-derived hyperpolarizing factors to the regulation of vascular tone in humans. Fundam Clin. Pharmacol., 2008, 22, 363-377.
    • (2008) Fundam Clin. Pharmacol. , vol.22 , pp. 363-377
    • Bellien, J.1    Thuillez, C.2    Joannides, R.3
  • 34
    • 55849095483 scopus 로고    scopus 로고
    • Signaling across myoendothelial gap junctions--fact or fiction?
    • de Wit, C.; Boettcher, M.; Schmidt, V.J. Signaling across myoendothelial gap junctions--fact or fiction?, Cell Commun. Adhes., 2008, 15, 231-245.
    • (2008) Cell Commun. Adhes. , vol.15 , pp. 231-245
    • de Wit, C.1    Boettcher, M.2    Schmidt, V.J.3
  • 36
    • 3042762368 scopus 로고    scopus 로고
    • Connexins pave the way for vascular communication
    • De Wit, C. Connexins pave the way for vascular communication. News Physiol Sci., 2004, 19, 148-153.
    • (2004) News Physiol Sci. , vol.19 , pp. 148-153
    • de Wit, C.1
  • 37
    • 16244370428 scopus 로고    scopus 로고
    • Regulation of blood flow in the microcirculation
    • Segal, S.S. Regulation of blood flow in the microcirculation. Microcirculation, 2005, 12, 33-45.
    • (2005) Microcirculation , vol.12 , pp. 33-45
    • Segal, S.S.1
  • 40
    • 0141590655 scopus 로고    scopus 로고
    • Lack of vascular connexin 40 is associated with hypertension and irregular arteriolar vasomotion
    • de Wit, C.; Roos, F.; Bolz, S.S.; Pohl, U. Lack of vascular connexin 40 is associated with hypertension and irregular arteriolar vasomotion. Physiol. Genomics, 2003, 13, 169-177.
    • (2003) Physiol. Genomics , vol.13 , pp. 169-177
    • de Wit, C.1    Roos, F.2    Bolz, S.S.3    Pohl, U.4
  • 41
    • 0032567887 scopus 로고    scopus 로고
    • Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block
    • Simon, A.M.; Goodenough, D.A.; Paul, D.L. Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block. Curr Biol., 1998, 8, 295-298.
    • (1998) Curr Biol. , vol.8 , pp. 295-298
    • Simon, A.M.1    Goodenough, D.A.2    Paul, D.L.3
  • 42
    • 0032567957 scopus 로고    scopus 로고
    • Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient mice
    • Kirchhoff, S.; Nelles, E.; Hagendorff, A.; Kruger, O.; Traub, O.; Willecke, K. Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient mice. Curr. Biol., 1998, 8, 299-302.
    • (1998) Curr. Biol. , vol.8 , pp. 299-302
    • Kirchhoff, S.1    Nelles, E.2    Hagendorff, A.3    Kruger, O.4    Traub, O.5    Willecke, K.6
  • 43
    • 0036436688 scopus 로고    scopus 로고
    • Vascular abnormalities in mice lacking the endothelial gap junction proteins connexin37 and connexin40
    • Simon, A.M.; McWhorter, A.R. Vascular abnormalities in mice lacking the endothelial gap junction proteins connexin37 and connexin40. Dev Biol., 2002, 251, 206-220.
    • (2002) Dev Biol. , vol.251 , pp. 206-220
    • Simon, A.M.1    McWhorter, A.R.2
  • 44
    • 0038010467 scopus 로고    scopus 로고
    • Decreased intercellular dyetransfer and downregulation of non-ablated connexins in aortic endothelium deficient in connexin37 or connexin40
    • Simon, A.M.; McWhorter, A.R. Decreased intercellular dyetransfer and downregulation of non-ablated connexins in aortic endothelium deficient in connexin37 or connexin40. J. Cell Sci., 2003, 116, 2223-2236.
    • (2003) J. Cell Sci. , vol.116 , pp. 2223-2236
    • Simon, A.M.1    McWhorter, A.R.2
  • 45
    • 0036244808 scopus 로고    scopus 로고
    • Altered dye diffusion and upregulation of connexin37 in mouse aortic endothelium deficient in connexin40
    • Kruger, O.; Beny, J.L.; Chabaud, F.; Traub, O.; Theis, M.; Brix, K.; Kirchhoff, S.; Willecke, K. Altered dye diffusion and upregulation of connexin37 in mouse aortic endothelium deficient in connexin40, J. Vasc. Res., 2002, 39, 160-172.
    • (2002) J. Vasc. Res. , vol.39 , pp. 160-172
    • Kruger, O.1    Beny, J.L.2    Chabaud, F.3    Traub, O.4    Theis, M.5    Brix, K.6    Kirchhoff, S.7    Willecke, K.8
  • 48
    • 0029787241 scopus 로고    scopus 로고
    • Endothelial nitric oxide synthase targeting to caveolae. Specific interactions with caveolin isoforms in cardiac myocytes and endothelial cells
    • Feron, O.; Belhassen, L.; Kobzik, L.; Smith, T.W.; Kelly, R.A.; Michel, T. Endothelial nitric oxide synthase targeting to caveolae. Specific interactions with caveolin isoforms in cardiac myocytes and endothelial cells. J. Biol. Chem., 1996, 271, 22810-22814.
    • (1996) J. Biol. Chem. , vol.271 , pp. 22810-22814
    • Feron, O.1    Belhassen, L.2    Kobzik, L.3    Smith, T.W.4    Kelly, R.A.5    Michel, T.6
  • 49
    • 77950484537 scopus 로고    scopus 로고
    • Caveolae, caveolin and control of vascular tone: Nitric oxide (NO) and endothelium derived hyperpolarizing factor (EDHF) regulation
    • Rath, G.; Dessy, C.; Feron, O. Caveolae, caveolin and control of vascular tone: nitric oxide (NO) and endothelium derived hyperpolarizing factor (EDHF) regulation. J. Physiol. Pharmacol., 2009, 60 Suppl 4, 105-109.
    • (2009) J. Physiol. Pharmacol. , vol.60 , Issue.SUPPL. 4 , pp. 105-109
    • Rath, G.1    Dessy, C.2    Feron, O.3
  • 50
    • 0026592806 scopus 로고
    • Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E
    • Zhang, S.H.; Reddick, R.L.; Piedrahita, J.A.; Maeda, N. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E. Science, 1992, 258, 468-471.
    • (1992) Science , vol.258 , pp. 468-471
    • Zhang, S.H.1    Reddick, R.L.2    Piedrahita, J.A.3    Maeda, N.4
  • 51
    • 0027258140 scopus 로고
    • Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery
    • Ishibashi, S.; Brown, M.S.; Goldstein, J.L.; Gerard, R.D.; Hammer, R.E.; Herz, J. Hypercholesterolemia in low density lipoprotein receptor knockout mice and its reversal by adenovirus-mediated gene delivery. J. Clin. Invest., 1993, 92, 883-893.
    • (1993) J. Clin. Invest. , vol.92 , pp. 883-893
    • Ishibashi, S.1    Brown, M.S.2    Goldstein, J.L.3    Gerard, R.D.4    Hammer, R.E.5    Herz, J.6
  • 53
    • 0034737654 scopus 로고    scopus 로고
    • Impaired conduction of vasodilation along arterioles in connexin40-deficient mice
    • de Wit, C.; Roos, F.; Bolz, S.S.; Kirchhoff, S.; Kruger, O.; Willecke, K.; Pohl, U. Impaired conduction of vasodilation along arterioles in connexin40-deficient mice. Circ. Res., 2000, 86, 649-655.
    • (2000) Circ. Res. , vol.86 , pp. 649-655
    • de Wit, C.1    Roos, F.2    Bolz, S.S.3    Kirchhoff, S.4    Kruger, O.5    Willecke, K.6    Pohl, U.7
  • 57
    • 0031016934 scopus 로고    scopus 로고
    • Female infertility in mice lacking connexin 37
    • Simon, A.M.; Goodenough, D.A.; Li, E.; Paul, D.L. Female infertility in mice lacking connexin 37. Nature, 1997, 385, 525-529.
    • (1997) Nature , vol.385 , pp. 525-529
    • Simon, A.M.1    Goodenough, D.A.2    Li, E.3    Paul, D.L.4
  • 58
    • 57049098245 scopus 로고    scopus 로고
    • Dissection of two Cx37-independent conducted vasodilator mechanisms by deletion of Cx40: Electrotonic versus regenerative conduction
    • Figueroa, X.F.; Duling, B.R. Dissection of two Cx37-independent conducted vasodilator mechanisms by deletion of Cx40: electrotonic versus regenerative conduction. Am. J. Physiol. Heart Circ. Physiol., 2008, 295, H2001-2007.
    • (2008) Am. J. Physiol. Heart Circ. Physiol. , vol.295
    • Figueroa, X.F.1    Duling, B.R.2
  • 61
    • 0027394095 scopus 로고
    • Gap junctional communication between vascular cells. Induction of connexin43 messenger RNA in macrophage foam cells of atherosclerotic lesions
    • Polacek, D.; Lal, R.; Volin, M.V.; Davies, P.F. Gap junctional communication between vascular cells. Induction of connexin43 messenger RNA in macrophage foam cells of atherosclerotic lesions, Am. J. Pathol., 1993, 142, 593-606.
    • (1993) Am. J. Pathol. , vol.142 , pp. 593-606
    • Polacek, D.1    Lal, R.2    Volin, M.V.3    Davies, P.F.4
  • 62
    • 33645002145 scopus 로고    scopus 로고
    • Shear stress and cyclic circumferential stretch, but not pressure, alter connexin43 expression in endothelial cells
    • Kwak, B.R.; Silacci, P.; Stergiopulos, N.; Hayoz, D.; Meda, P. Shear stress and cyclic circumferential stretch, but not pressure, alter connexin43 expression in endothelial cells. Cell Commun. Adhes., 2005, 12, 261-270.
    • (2005) Cell Commun. Adhes. , vol.12 , pp. 261-270
    • Kwak, B.R.1    Silacci, P.2    Stergiopulos, N.3    Hayoz, D.4    Meda, P.5
  • 63
    • 0032550290 scopus 로고    scopus 로고
    • Regulation of vascular connexin43 gene expression by mechanical loads
    • Cowan, D.B.; Lye, S.J.; Langille, B.L. Regulation of vascular connexin43 gene expression by mechanical loads. Circ. Res., 1998, 82, 786-793.
    • (1998) Circ. Res. , vol.82 , pp. 786-793
    • Cowan, D.B.1    Lye, S.J.2    Langille, B.L.3
  • 64
    • 0037465360 scopus 로고    scopus 로고
    • Reduced connexin43 expression inhibits atherosclerotic lesion formation in low-density lipoprotein receptor-deficient mice
    • Kwak, B.R.; Veillard, N.; Pelli, G.; Mulhaupt, F.; James, R.W.; Chanson, M.; Mach, F. Reduced connexin43 expression inhibits atherosclerotic lesion formation in low-density lipoprotein receptor-deficient mice. Circulation, 2003, 107, 1033-1039.
    • (2003) Circulation , vol.107 , pp. 1033-1039
    • Kwak, B.R.1    Veillard, N.2    Pelli, G.3    Mulhaupt, F.4    James, R.W.5    Chanson, M.6    Mach, F.7
  • 65
    • 0027407183 scopus 로고
    • Expression of connexin43 gap junctions between cultured vascular smooth muscle cells is dependent upon phenotype
    • Rennick, R.E.; Connat, J.L.; Burnstock, G.; Rothery, S.; Severs, N.J.; Green, C.R. Expression of connexin43 gap junctions between cultured vascular smooth muscle cells is dependent upon phenotype, Cell Tissue Res., 1993, 271, 323-332.
    • (1993) Cell Tissue Res. , vol.271 , pp. 323-332
    • Rennick, R.E.1    Connat, J.L.2    Burnstock, G.3    Rothery, S.4    Severs, N.J.5    Green, C.R.6
  • 66
    • 41449115125 scopus 로고    scopus 로고
    • Targeting connexin 43 prevents platelet-derived growth factor-BB-induced phenotypic change in porcine coronary artery smooth muscle cells
    • Chadjichristos, C.E.; Morel, S.; Derouette, J.P.; Sutter, E.; Roth, I.; Brisset, A.C.; Bochaton-Piallat, M. L.; Kwak, B.R. Targeting connexin 43 prevents platelet-derived growth factor-BB-induced phenotypic change in porcine coronary artery smooth muscle cells. Circ. Res., 2008, 102, 653-660.
    • (2008) Circ. Res. , vol.102 , pp. 653-660
    • Chadjichristos, C.E.1    Morel, S.2    Derouette, J.P.3    Sutter, E.4    Roth, I.5    Brisset, A.C.6    Bochaton-Piallat, M.L.7    Kwak, B.R.8
  • 67
    • 0043235647 scopus 로고    scopus 로고
    • Reduced expression of endothelial connexin37 and connexin40 in hyperlipidemic mice: Recovery of connexin37 after 7-day simvastatin treatment
    • Yeh, H.I.; Lu, C.S.; Wu, Y.J.; Chen, C.C.; Hong, R.C.; Ko, Y.S.; Shiao, M.S.; Severs, N.J.; Tsai, C.H. Reduced expression of endothelial connexin37 and connexin40 in hyperlipidemic mice: recovery of connexin37 after 7-day simvastatin treatment. Arterioscler Thromb. Vasc. Biol., 2003, 23, 1391-1397.
    • (2003) Arterioscler Thromb. Vasc. Biol. , vol.23 , pp. 1391-1397
    • Yeh, H.I.1    Lu, C.S.2    Wu, Y.J.3    Chen, C.C.4    Hong, R.C.5    Ko, Y.S.6    Shiao, M.S.7    Severs, N.J.8    Tsai, C.H.9
  • 68
    • 1942502888 scopus 로고    scopus 로고
    • Connexins in leukocytes: Shuttling messages?
    • Wong, C.W.; Christen, T.; Kwak, B.R. Connexins in leukocytes: shuttling messages? Cardiovasc. Res., 2004, 62, 357-367.
    • (2004) Cardiovasc. Res. , vol.62 , pp. 357-367
    • Wong, C.W.1    Christen, T.2    Kwak, B.R.3
  • 69
    • 52949118482 scopus 로고    scopus 로고
    • The multifaceted contributions of leukocyte subsets to atherosclerosis: Lessons from mouse models
    • Weber, C.; Zernecke, A.; Libby, P. The multifaceted contributions of leukocyte subsets to atherosclerosis: lessons from mouse models. Nat. Rev. Immunol., 2008, 8, 802-815.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 802-815
    • Weber, C.1    Zernecke, A.2    Libby, P.3
  • 70
    • 73349092422 scopus 로고    scopus 로고
    • Macrophage heterogeneity in atherosclerotic plaques
    • Johnson, J.L.; Newby, A.C. Macrophage heterogeneity in atherosclerotic plaques. Curr. Opin. Lipidol., 2009, 20, 370-378.
    • (2009) Curr. Opin. Lipidol. , vol.20 , pp. 370-378
    • Johnson, J.L.1    Newby, A.C.2
  • 71
    • 0037245113 scopus 로고    scopus 로고
    • Gap-junctional coupling between neutrophils and endothelial cells: A novel modulator of transendothelial migration
    • Zahler, S.; Hoffmann, A.; Gloe, T.; Pohl, U. Gap-junctional coupling between neutrophils and endothelial cells: a novel modulator of transendothelial migration. J. Leukoc Biol., 2003, 73, 118-126.
    • (2003) J. Leukoc Biol. , vol.73 , pp. 118-126
    • Zahler, S.1    Hoffmann, A.2    Gloe, T.3    Pohl, U.4
  • 72
    • 0029089965 scopus 로고
    • Leukocytes express connexin 43 after activation with lipopolysaccharide and appear to form gap junctions with endothelial cells after ischemia-reperfusion
    • Jara, P.I.; Boric, M.P.; Saez, J.C. Leukocytes express connexin 43 after activation with lipopolysaccharide and appear to form gap junctions with endothelial cells after ischemia-reperfusion, Proc. Natl. Acad Sci. U S A., 1995, 92, 7011-7015.
    • (1995) Proc. Natl. Acad Sci. U S A. , vol.92 , pp. 7011-7015
    • Jara, P.I.1    Boric, M.P.2    Saez, J.C.3
  • 75
    • 42649114478 scopus 로고    scopus 로고
    • Endothelial connexins are downregulated by atherogenic factors
    • Hou, C.J.; Tsai, C.H.; Yeh, H.I. Endothelial connexins are downregulated by atherogenic factors. Front Biosci., 2008, 13, 3549-3557.
    • (2008) Front Biosci. , vol.13 , pp. 3549-3557
    • Hou, C.J.1    Tsai, C.H.2    Yeh, H.I.3
  • 76
    • 22244490333 scopus 로고    scopus 로고
    • The role of hyperhomocysteinemia in nitric oxide (NO) and endothelium-derived hyperpolarizing factor (EDHF)-mediated vasodilatation
    • Heil, S.G.; De Vriese, A.S.; Kluijtmans, L.A.; Mortier, S.; Den Heijer, M.; Blom, H.J. The role of hyperhomocysteinemia in nitric oxide (NO) and endothelium-derived hyperpolarizing factor (EDHF)-mediated vasodilatation. Cell Mol. Biol. (Noisy-le-grand). 2004, 50, 911-916.
    • (2004) Cell Mol. Biol. (Noisy-le-grand) , vol.50 , pp. 911-916
    • Heil, S.G.1    de Vriese, A.S.2    Kluijtmans, L.A.3    Mortier, S.4    den Heijer, M.5    Blom, H.J.6
  • 77
    • 0032055505 scopus 로고    scopus 로고
    • Tumour necrosis factor alpha alters the expression of connexin43, connexin40, and connexin37 in human umbilical vein endothelial cells
    • van Rijen, H.V.; van Kempen, M.J.; Postma, S.; Jongsma, H.J. Tumour necrosis factor alpha alters the expression of connexin43, connexin40, and connexin37 in human umbilical vein endothelial cells. Cytokine, 1998, 10, 258-264.
    • (1998) Cytokine , vol.10 , pp. 258-264
    • van Rijen, H.V.1    van Kempen, M.J.2    Postma, S.3    Jongsma, H.J.4
  • 79
    • 1942502918 scopus 로고    scopus 로고
    • Genetically modified mice: Tools to decode the functions of connexins in the heart-new models for cardiovascular research
    • Gros, D.; Dupays, L.; Alcolea, S.; Meysen, S.; Miquerol, L.; Theveniau-Ruissy, M. Genetically modified mice: tools to decode the functions of connexins in the heart-new models for cardiovascular research. Cardiovasc. Res., 2004, 62, 299-308.
    • (2004) Cardiovasc. Res. , vol.62 , pp. 299-308
    • Gros, D.1    Dupays, L.2    Alcolea, S.3    Meysen, S.4    Miquerol, L.5    Theveniau-Ruissy, M.6
  • 81
    • 0035045165 scopus 로고    scopus 로고
    • Connexin45 is the first connexin to be expressed in the central conduction system of the mouse heart
    • Coppen, S.R.; Gourdie, R.G.; Severs, N.J. Connexin45 is the first connexin to be expressed in the central conduction system of the mouse heart. Exp. Clin. Cardiol., 2001, 6, 17-23.
    • (2001) Exp. Clin. Cardiol. , vol.6 , pp. 17-23
    • Coppen, S.R.1    Gourdie, R.G.2    Severs, N.J.3
  • 82
  • 83
    • 0043026950 scopus 로고    scopus 로고
    • High incidence of cardiac malformations in connexin40-deficient mice
    • Gu, H.; Smith, F.C.; Taffet, S.M.; Delmar, M. High incidence of cardiac malformations in connexin40-deficient mice. Circ. Res., 2003, 93, 201-206.
    • (2003) Circ. Res. , vol.93 , pp. 201-206
    • Gu, H.1    Smith, F.C.2    Taffet, S.M.3    Delmar, M.4
  • 84
    • 0032517847 scopus 로고    scopus 로고
    • Gap junction-mediated cell-cell communication modulates mouse neural crest migration
    • Huang, G.Y.; Cooper, E.S.; Waldo, K.; Kirby, M.L.; Gilula, N.B.; Lo, C.W. Gap junction-mediated cell-cell communication modulates mouse neural crest migration. J. Cell Biol., 1998, 143, 1725-1734.
    • (1998) J. Cell Biol. , vol.143 , pp. 1725-1734
    • Huang, G.Y.1    Cooper, E.S.2    Waldo, K.3    Kirby, M.L.4    Gilula, N.B.5    Lo, C.W.6
  • 85
    • 0032373862 scopus 로고    scopus 로고
    • Heart malformations in transgenic mice exhibiting dominant negative inhibition of gap junctional communication in neural crest cells
    • Sullivan, R.; Huang, G.Y.; Meyer, R.A.; Wessels, A.; Linask, K.K.; Lo, C.W. Heart malformations in transgenic mice exhibiting dominant negative inhibition of gap junctional communication in neural crest cells. Dev. Biol., 1998, 204, 224-234.
    • (1998) Dev. Biol. , vol.204 , pp. 224-234
    • Sullivan, R.1    Huang, G.Y.2    Meyer, R.A.3    Wessels, A.4    Linask, K.K.5    Lo, C.W.6
  • 86
  • 87
    • 33745094980 scopus 로고    scopus 로고
    • Distinct cardiac malformations caused by absence of connexin 43 in the neural crest and in the non-crest neural tube
    • Liu, S.; Liu, F.; Schneider, A.E.; St. Amand, T.; Epstein, J.A.; Gutstein, D.E. Distinct cardiac malformations caused by absence of connexin 43 in the neural crest and in the non-crest neural tube, Development, 2006, 133, 2063-2073.
    • (2006) Development , vol.133 , pp. 2063-2073
    • Liu, S.1    Liu, F.2    Schneider, A.E.3    St. Amand, T.4    Epstein, J.A.5    Gutstein, D.E.6
  • 88
    • 0031024666 scopus 로고    scopus 로고
    • Dissociated spatial patterning of gap junctions and cell adhesion junctions during postnatal differentiation of ventricular myocardium
    • Angst, B.D.; Khan, L.U.; Severs, N.J.; Whitely, K.; Rothery, S.; Thompson, R.P.; Magee, A.I.; Gourdie, R.G. Dissociated spatial patterning of gap junctions and cell adhesion junctions during postnatal differentiation of ventricular myocardium. Circ. Res., 1997, 80, 88-94.
    • (1997) Circ. Res. , vol.80 , pp. 88-94
    • Angst, B.D.1    Khan, L.U.2    Severs, N.J.3    Whitely, K.4    Rothery, S.5    Thompson, R.P.6    Magee, A.I.7    Gourdie, R.G.8
  • 89
  • 90
    • 51749110724 scopus 로고    scopus 로고
    • Remodelling of gap junctions and connexin expression in diseased myocardium
    • Severs, N. J.; Bruce, A.F.; Dupont, E.; Rothery, S. Remodelling of gap junctions and connexin expression in diseased myocardium. Cardiovasc. Res., 2008, 80, 9-19.
    • (2008) Cardiovasc. Res. , vol.80 , pp. 9-19
    • Severs, N.J.1    Bruce, A.F.2    Dupont, E.3    Rothery, S.4
  • 93
    • 0034717680 scopus 로고    scopus 로고
    • Phosphorylation of connexin43 on serine368 by protein kinase C regulates gap junctional communication
    • Lampe, P.D.; TenBroek, E.M.; Burt, J.M.; Kurata, W.E.; Johnson, R.G.; Lau, A.F. Phosphorylation of connexin43 on serine368 by protein kinase C regulates gap junctional communication. J. Cell Biol., 2000, 149, 1503-1512.
    • (2000) J. Cell Biol. , vol.149 , pp. 1503-1512
    • Lampe, P.D.1    TenBroek, E.M.2    Burt, J.M.3    Kurata, W.E.4    Johnson, R.G.5    Lau, A.F.6
  • 94
    • 0035945355 scopus 로고    scopus 로고
    • Ser364 of connexin43 and the upregulation of gap junction assembly by cAMP
    • TenBroek, E.M.; Lampe, P.D.; Solan, J.L.; Reynhout, J.K.; Johnson, R.G. Ser364 of connexin43 and the upregulation of gap junction assembly by cAMP. J. Cell Biol., 2001, 155, 1307-1318.
    • (2001) J. Cell Biol. , vol.155 , pp. 1307-1318
    • TenBroek, E.M.1    Lampe, P.D.2    Solan, J.L.3    Reynhout, J.K.4    Johnson, R.G.5
  • 95
    • 0026464786 scopus 로고
    • Cardiac gap junctions: Three distinct single channel conductances and their modulation by phosphorylating treatments
    • Takens-Kwak, B.R.; Jongsma, H.J. Cardiac gap junctions: three distinct single channel conductances and their modulation by phosphorylating treatments. Pflugers Arch., 1992, 422, 198-200.
    • (1992) Pflugers Arch. , vol.422 , pp. 198-200
    • Takens-Kwak, B.R.1    Jongsma, H.J.2
  • 97
    • 33748795808 scopus 로고    scopus 로고
    • Analysis of Connexin43 phosphorylated at S325, S328 and S330 in normoxic and ischemic heart
    • Lampe, P.D.; Cooper, C.D.; King, T.J.; Burt, J.M. Analysis of Connexin43 phosphorylated at S325, S328 and S330 in normoxic and ischemic heart. J. Cell Sci., 2006, 119, 3435-3442.
    • (2006) J. Cell Sci. , vol.119 , pp. 3435-3442
    • Lampe, P.D.1    Cooper, C.D.2    King, T.J.3    Burt, J.M.4
  • 98
    • 13844322129 scopus 로고    scopus 로고
    • Downregulation of connexin43 in early myocardial ischemia and protective effect by ischemic preconditioning in rat hearts in vivo
    • Hatanaka, K.; Kawata, H.; Toyofuku, T.; Yoshida, K. Downregulation of connexin43 in early myocardial ischemia and protective effect by ischemic preconditioning in rat hearts in vivo. Jpn. Heart J., 2004, 45, 1007-1019.
    • (2004) Jpn. Heart J. , vol.45 , pp. 1007-1019
    • Hatanaka, K.1    Kawata, H.2    Toyofuku, T.3    Yoshida, K.4
  • 99
    • 33746566071 scopus 로고    scopus 로고
    • Selectivity of connexin 43 channels is regulated through protein kinase C-dependent phosphorylation
    • Ek-Vitorin, J.F.; King, T.J.; Heyman, N.S.; Lampe, P.D.; Burt, J.M. Selectivity of connexin 43 channels is regulated through protein kinase C-dependent phosphorylation. Circ. Res., 2006, 98, 1498-1505.
    • (2006) Circ. Res. , vol.98 , pp. 1498-1505
    • Ek-Vitorin, J.F.1    King, T.J.2    Heyman, N.S.3    Lampe, P.D.4    Burt, J.M.5
  • 100
    • 0034620495 scopus 로고    scopus 로고
    • Accelerated onset and increased incidence of ventricular arrhythmias induced by ischemia in Cx43-deficient mice
    • Lerner, D.L.; Yamada, K.A.; Schuessler, R.B.; Saffitz, J.E. Accelerated onset and increased incidence of ventricular arrhythmias induced by ischemia in Cx43-deficient mice. Circulation, 2000, 101, 547-552.
    • (2000) Circulation , vol.101 , pp. 547-552
    • Lerner, D.L.1    Yamada, K.A.2    Schuessler, R.B.3    Saffitz, J.E.4
  • 101
    • 70849099466 scopus 로고    scopus 로고
    • Cx43 CT Domain Influences Infarct Size and Susceptibility to Ventricular Tachyarrhythmias in Acute Myocardial Infarction
    • Maass, K.; Chase, S.E.; Lin, X.; Delmar, M. Cx43 CT Domain Influences Infarct Size and Susceptibility to Ventricular Tachyarrhythmias in Acute Myocardial Infarction. Cardiovasc. Res., 2009.
    • (2009) Cardiovasc. Res.
    • Maass, K.1    Chase, S.E.2    Lin, X.3    Delmar, M.4
  • 102
    • 1142297603 scopus 로고    scopus 로고
    • Gap junction-mediated spread of cell injury and death during myocardial ischemia-reperfusion
    • Garcia-Dorado, D.; Rodriguez-Sinovas, A.; Ruiz-Meana, M. Gap junction-mediated spread of cell injury and death during myocardial ischemia-reperfusion, Cardiovasc. Res., 2004, 61, 386-401.
    • (2004) Cardiovasc. Res. , vol.61 , pp. 386-401
    • Garcia-Dorado, D.1    Rodriguez-Sinovas, A.2    Ruiz-Meana, M.3
  • 104
    • 0037454041 scopus 로고    scopus 로고
    • Connexin43 as a determinant of myocardial infarct size following coronary occlusion in mice
    • Kanno, S.; Kovacs, A.; Yamada, K.A.; Saffitz, J.E. Connexin43 as a determinant of myocardial infarct size following coronary occlusion in mice. J. Am. Coll Cardiol., 2003, 41, 681-686.
    • (2003) J. Am. Coll Cardiol. , vol.41 , pp. 681-686
    • Kanno, S.1    Kovacs, A.2    Yamada, K.A.3    Saffitz, J.E.4
  • 105
    • 0033529651 scopus 로고    scopus 로고
    • Propagation of cardiomyocyte hypercontracture by passage of Na(+) through gap junctions
    • Ruiz-Meana, M.; Garcia-Dorado, D.; Hofstaetter, B.; Piper, H.M.; Soler-Soler, J. Propagation of cardiomyocyte hypercontracture by passage of Na(+) through gap junctions. Circ. Res., 1999, 85, 280-287.
    • (1999) Circ. Res. , vol.85 , pp. 280-287
    • Ruiz-Meana, M.1    Garcia-Dorado, D.2    Hofstaetter, B.3    Piper, H.M.4    Soler-Soler, J.5
  • 106
    • 0030780568 scopus 로고    scopus 로고
    • Gap junction uncoupler heptanol prevents cell-to-cell progression of hypercontracture and limits necrosis during myocardial reperfusion
    • Garcia-Dorado, D.; Inserte, J.; Ruiz-Meana, M.; Gonzalez, M.A.; Solares, J.; Julia, M.; Barrabes, J.A.; Soler-Soler, J. Gap junction uncoupler heptanol prevents cell-to-cell progression of hypercontracture and limits necrosis during myocardial reperfusion. Circulation, 1997, 96, 3579-3586.
    • (1997) Circulation , vol.96 , pp. 3579-3586
    • Garcia-Dorado, D.1    Inserte, J.2    Ruiz-Meana, M.3    Gonzalez, M.A.4    Solares, J.5    Julia, M.6    Barrabes, J.A.7    Soler-Soler, J.8
  • 107
    • 0030747523 scopus 로고    scopus 로고
    • Halothane reduces reperfusion injury after regional ischaemia in the rabbit heart in vivo
    • Schlack, W.; Preckel, B.; Barthel, H.; Obal, D.; Thamer, V. Halothane reduces reperfusion injury after regional ischaemia in the rabbit heart in vivo. Br. J. Anaesth, 1997, 79, 88-96.
    • (1997) Br. J. Anaesth , vol.79 , pp. 88-96
    • Schlack, W.1    Preckel, B.2    Barthel, H.3    Obal, D.4    Thamer, V.5
  • 108
    • 0035693047 scopus 로고    scopus 로고
    • Activation of connexin-43 hemichannels can elevate [Ca(2+)]i and [Na(+)]i in rabbit ventricular myocytes during metabolic inhibition
    • Li, F.; Sugishita, K.; Su, Z.; Ueda, I.; Barry, W.H. Activation of connexin-43 hemichannels can elevate [Ca(2+)]i and [Na(+)]i in rabbit ventricular myocytes during metabolic inhibition. J. Mol. Cell Cardiol., 2001, 33, 2145-2155.
    • (2001) J. Mol. Cell Cardiol. , vol.33 , pp. 2145-2155
    • Li, F.1    Sugishita, K.2    Su, Z.3    Ueda, I.4    Barry, W.H.5
  • 109
    • 34548459834 scopus 로고    scopus 로고
    • Hemichannels in cardiomyocytes open transiently during ischemia and contribute to reperfusion injury following brief ischemia
    • Shintani-Ishida, K.; Uemura, K.; Yoshida, K. Hemichannels in cardiomyocytes open transiently during ischemia and contribute to reperfusion injury following brief ischemia. Am. J. Physiol. Heart Circ. Physiol., 2007, 293, H1714-1720.
    • (2007) Am. J. Physiol. Heart Circ. Physiol. , vol.293
    • Shintani-Ishida, K.1    Uemura, K.2    Yoshida, K.3
  • 111
    • 39149102487 scopus 로고    scopus 로고
    • ATP release by way of connexin 36 hemichannels mediates ischemic tolerance in vitro
    • Schock, S.C.; Leblanc, D.; Hakim, A.M.; Thompson, C.S. ATP release by way of connexin 36 hemichannels mediates ischemic tolerance in vitro. Biochem. Biophys. Res. Commun., 2008, 368, 138-144.
    • (2008) Biochem. Biophys. Res. Commun. , vol.368 , pp. 138-144
    • Schock, S.C.1    Leblanc, D.2    Hakim, A.M.3    Thompson, C.S.4
  • 114
    • 0029119513 scopus 로고
    • TPA increases conductance but decreases permeability in neonatal rat cardiomyocyte gap junction channels
    • Kwak, B.R.; van Veen, T.A.; Analbers, L.J.; Jongsma, H.J. TPA increases conductance but decreases permeability in neonatal rat cardiomyocyte gap junction channels. Exp. Cell Res., 1995, 220, 456-463.
    • (1995) Exp. Cell Res. , vol.220 , pp. 456-463
    • Kwak, B.R.1    van Veen, T.A.2    Analbers, L.J.3    Jongsma, H.J.4
  • 115
    • 0029878244 scopus 로고    scopus 로고
    • Regulation of cardiac gap junction channel permeability and conductance by several phosphorylating conditions
    • Kwak, B.R.; Jongsma, H.J. Regulation of cardiac gap junction channel permeability and conductance by several phosphorylating conditions. Mol. Cell Biochem., 1996, 157, 93-99.
    • (1996) Mol. Cell Biochem. , vol.157 , pp. 93-99
    • Kwak, B.R.1    Jongsma, H.J.2
  • 116
    • 0038727330 scopus 로고    scopus 로고
    • Mechanisms of delayed electrical uncoupling induced by ischemic preconditioning
    • Jain, S.K.; Schuessler, R.B.; Saffitz, J.E. Mechanisms of delayed electrical uncoupling induced by ischemic preconditioning. Circ. Res., 2003, 92, 1138-1144.
    • (2003) Circ. Res. , vol.92 , pp. 1138-1144
    • Jain, S.K.1    Schuessler, R.B.2    Saffitz, J.E.3
  • 117
    • 0030760513 scopus 로고    scopus 로고
    • Ischemic preconditioning decreases apoptosis in rat hearts in vivo
    • Piot, C.A.; Padmanaban, D.; Ursell, P. C.; Sievers, R.E.; Wolfe, C.L. Ischemic preconditioning decreases apoptosis in rat hearts in vivo. Circulation, 1997, 96, 1598-1604.
    • (1997) Circulation , vol.96 , pp. 1598-1604
    • Piot, C.A.1    Padmanaban, D.2    Ursell, P.C.3    Sievers, R.E.4    Wolfe, C.L.5
  • 118
    • 0037590100 scopus 로고    scopus 로고
    • Ischemic preconditioning preserves connexin 43 phosphorylation during sustained ischemia in pig hearts in vivo
    • Schulz, R.; Gres, P.; Skyschally, A.; Duschin, A.; Belosjorow, S.; Konietzka, I.; Heusch, G. Ischemic preconditioning preserves connexin 43 phosphorylation during sustained ischemia in pig hearts in vivo. FASEB J., 2003, 17, 1355-1357.
    • (2003) FASEB J. , vol.17 , pp. 1355-1357
    • Schulz, R.1    Gres, P.2    Skyschally, A.3    Duschin, A.4    Belosjorow, S.5    Konietzka, I.6    Heusch, G.7
  • 121
    • 0347635344 scopus 로고    scopus 로고
    • Role of connexin 43 in ischemic preconditioning does not involve intercellular communication through gap junctions
    • Li, X.; Heinzel, F.R.; Boengler, K.; Schulz, R.; Heusch, G. Role of connexin 43 in ischemic preconditioning does not involve intercellular communication through gap junctions. J. Mol. Cell Cardiol., 2004, 36, 161-163.
    • (2004) J. Mol. Cell Cardiol. , vol.36 , pp. 161-163
    • Li, X.1    Heinzel, F.R.2    Boengler, K.3    Schulz, R.4    Heusch, G.5
  • 122
    • 77949669901 scopus 로고    scopus 로고
    • Role of the gap junction in ischemic preconditioning in the heart
    • Miura, T.; Miki, T.; Yano, T. Role of the gap junction in ischemic preconditioning in the heart. Am. J. Physiol. Heart Circ. Physiol., 2010, 298, H1115-1125.
    • (2010) Am. J. Physiol. Heart Circ. Physiol. , vol.298
    • Miura, T.1    Miki, T.2    Yano, T.3
  • 123
    • 0036101594 scopus 로고    scopus 로고
    • The gap junction uncoupler heptanol abrogates infarct size reduction with preconditioning in mouse hearts
    • Li, G.; Whittaker, P.; Yao, M.; Kloner, R.A.; Przyklenk, K. The gap junction uncoupler heptanol abrogates infarct size reduction with preconditioning in mouse hearts. Cardiovasc Pathol., 2002, 11, 158-165.
    • (2002) Cardiovasc Pathol. , vol.11 , pp. 158-165
    • Li, G.1    Whittaker, P.2    Yao, M.3    Kloner, R.A.4    Przyklenk, K.5
  • 125
    • 34247850423 scopus 로고    scopus 로고
    • Gap junctional uncoupling plays a trigger role in the antiarrhythmic effect of ischaemic preconditioning
    • Papp, R.; Gonczi, M.; Kovacs, M.; Seprenyi, G.; Vegh, A. Gap junctional uncoupling plays a trigger role in the antiarrhythmic effect of ischaemic preconditioning. Cardiovasc Res., 2007, 74, 396-405.
    • (2007) Cardiovasc Res. , vol.74 , pp. 396-405
    • Papp, R.1    Gonczi, M.2    Kovacs, M.3    Seprenyi, G.4    Vegh, A.5
  • 128
    • 25444512382 scopus 로고    scopus 로고
    • Impairment of diazoxide-induced formation of reactive oxygen species and loss of cardioprotection in connexin 43 deficient mice
    • Heinzel, F.R.; Luo, Y.; Li, X.; Boengler, K.; Buechert, A.; Garcia-Dorado, D.; Di Lisa, F.; Schulz, R.; Heusch, G. Impairment of diazoxide-induced formation of reactive oxygen species and loss of cardioprotection in connexin 43 deficient mice. Circ. Res., 2005, 97, 583-586.
    • (2005) Circ. Res. , vol.97 , pp. 583-586
    • Heinzel, F.R.1    Luo, Y.2    Li, X.3    Boengler, K.4    Buechert, A.5    Garcia-Dorado, D.6    di Lisa, F.7    Schulz, R.8    Heusch, G.9
  • 132
    • 0019179777 scopus 로고
    • Studies on heart. XIX. Isolation of an atrial peptide that improves the rhythmicity of cultured myocardial cell clusters
    • Aonuma, S.; Kohama, Y.; Akai, K.; Komiyama, Y.; Nakajima, S.; Wakabayashi, M.; Makino, T. Studies on heart. XIX. Isolation of an atrial peptide that improves the rhythmicity of cultured myocardial cell clusters. Chem. Pharm. Bull (Tokyo), 1980, 28, 3332-3339.
    • (1980) Chem. Pharm. Bull (Tokyo) , vol.28 , pp. 3332-3339
    • Aonuma, S.1    Kohama, Y.2    Akai, K.3    Komiyama, Y.4    Nakajima, S.5    Wakabayashi, M.6    Makino, T.7
  • 133
    • 0034968994 scopus 로고    scopus 로고
    • Structure-activity relationships of novel peptides related to the antiarrhythmic peptide AAP10 which reduce the dispersion of epicardial action potential duration
    • Grover, R.; Dhein, S. Structure-activity relationships of novel peptides related to the antiarrhythmic peptide AAP10 which reduce the dispersion of epicardial action potential duration. Peptides, 2001, 22, 1011-1021.
    • (2001) Peptides , vol.22 , pp. 1011-1021
    • Grover, R.1    Dhein, S.2
  • 134
    • 0042889320 scopus 로고    scopus 로고
    • Pharmacological characterization of the new stable antiarrhythmic peptide analog Ac-D-Tyr-D-Pro-D-Hyp-Gly-D-Ala-Gly-NH2 (ZP123): In vivo and in vitro studies
    • Kjolbye, A.L.; Knudsen, C.B.; Jepsen, T.; Larsen, B.D.; Petersen, J.S. Pharmacological characterization of the new stable antiarrhythmic peptide analog Ac-D-Tyr-D-Pro-D-Hyp-Gly-D-Ala-Gly-NH2 (ZP123): in vivo and in vitro studies. J. Pharmacol. Exp. Ther., 2003, 306, 1191-1199.
    • (2003) J. Pharmacol. Exp. Ther. , vol.306 , pp. 1191-1199
    • Kjolbye, A.L.1    Knudsen, C.B.2    Jepsen, T.3    Larsen, B.D.4    Petersen, J.S.5
  • 135
    • 0036634865 scopus 로고    scopus 로고
    • Pharmacological modification of gap junction coupling by an antiarrhythmic peptide via protein kinase C activation
    • Weng, S.; Lauven, M.; Schaefer, T.; Polontchouk, L.; Grover, R.; Dhein, S. Pharmacological modification of gap junction coupling by an antiarrhythmic peptide via protein kinase C activation. FASEB J. 2002, 16, 1114-1116.
    • (2002) FASEB J. , vol.16 , pp. 1114-1116
    • Weng, S.1    Lauven, M.2    Schaefer, T.3    Polontchouk, L.4    Grover, R.5    Dhein, S.6
  • 138
    • 54249150370 scopus 로고    scopus 로고
    • Local effects and mechanisms of antiarrhythmic peptide AAP10 in acute regional myocardial ischemia: Electrophysiological and molecular findings
    • Jozwiak, J.; Dhein, S. Local effects and mechanisms of antiarrhythmic peptide AAP10 in acute regional myocardial ischemia: electrophysiological and molecular findings. Naunyn Schmiedebergs Arch. Pharmacol., 2008, 378, 459-470.
    • (2008) Naunyn Schmiedebergs Arch. Pharmacol. , vol.378 , pp. 459-470
    • Jozwiak, J.1    Dhein, S.2
  • 139
    • 67349277678 scopus 로고    scopus 로고
    • The anti-arrhythmic peptide AAP10 remodels Cx43 and Cx40 expression and function
    • Easton, J.A.; Petersen, J. S.; Martin, P.E. The anti-arrhythmic peptide AAP10 remodels Cx43 and Cx40 expression and function. Naunyn Schmiedebergs Arch. Pharmacol., 2009, 380, 11-24.
    • (2009) Naunyn Schmiedebergs Arch. Pharmacol. , vol.380 , pp. 11-24
    • Easton, J.A.1    Petersen, J.S.2    Martin, P.E.3
  • 140
    • 33646120315 scopus 로고    scopus 로고
    • The antiarrhythmic peptide rotigaptide (ZP123) increases connexin 43 protein expression in neonatal rat ventricular cardiomyocytes
    • Stahlhut, M.; Petersen, J.S.; Hennan, J.K.; Ramirez, M.T. The antiarrhythmic peptide rotigaptide (ZP123) increases connexin 43 protein expression in neonatal rat ventricular cardiomyocytes. Cell Commun Adhes., 2006, 13, 21-27.
    • (2006) Cell Commun Adhes. , vol.13 , pp. 21-27
    • Stahlhut, M.1    Petersen, J.S.2    Hennan, J.K.3    Ramirez, M.T.4
  • 141
    • 67650266546 scopus 로고    scopus 로고
    • Human cardiac gap-junction coupling: Effects of antiarrhythmic peptide AAP10
    • Hagen, A.; Dietze, A.; Dhein, S. Human cardiac gap-junction coupling: effects of antiarrhythmic peptide AAP10. Cardiovasc. Res., 2009, 83, 405-415.
    • (2009) Cardiovasc. Res. , vol.83 , pp. 405-415
    • Hagen, A.1    Dietze, A.2    Dhein, S.3
  • 142
    • 33644823558 scopus 로고    scopus 로고
    • The antiarrhythmic peptide rotigaptide (ZP123) increases gap junction intercellular communication in cardiac myocytes and HeLa cells expressing connexin 43
    • Clarke, T.C.; Thomas, D.; Petersen, J.S.; Evans, W.H.; Martin, P.E. The antiarrhythmic peptide rotigaptide (ZP123) increases gap junction intercellular communication in cardiac myocytes and HeLa cells expressing connexin 43. Br J. Pharmacol., 2006, 147, 486-495.
    • (2006) Br J. Pharmacol. , vol.147 , pp. 486-495
    • Clarke, T.C.1    Thomas, D.2    Petersen, J.S.3    Evans, W.H.4    Martin, P.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.