Structure-activity relationships of novel peptides related to the antiarrhythmic peptide AAP10 which reduce the dispersion of epicardial action potential duration

Peptides

Volumn 22, Issue 7, 2001, Pages 1011-1021

  Grover, Rajiv ^a   Dhein, Stefan ^b  

^a UNIVERSITY OF COLOGNE   (Germany)

^b MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Antiarrhythmic peptide; Cardiac ischemia; Gap Junction; Structure activity relationships

Indexed keywords

AAP 10; ALANYLALANYLGLYCYLHYDROXYPROLYLPROLYLTYROSINE; ANTIARRHYTHMIC PEPTIDE; ANTIARRHYTHMIC PEPTIDE AAP3DP; ANTIARRHYTMIC PEPTIDE AA7DP; ANTIARRHYTMIC PEPTIDE AAP10TT; ANTIARRHYTMIC PEPTIDE AAP11TT; ANTIARRHYTMIC PEPTIDE AAP13TT; ANTIARRHYTMIC PEPTIDE AAP6DP; ANTIARRHYTMIC PEPTIDE AAP8DP; ANTIARRHYTMIC PEPTIDE AAP8TT; ANTIARRYHTMIC PEPTIDE AAP8CM; ARGINYLALANYLGLYCYLHYDROXYPROLYLPROLYLTYROSINE; CYCLOPEPTIDE; CYCLOPEPTIDE CAAP10RG; GLYCYLALANYLGLYCYLHYDROXYPROLYLHISTIDYLTYROSINE; GLYCYLALANYLGLYCYLHYDROXYPROLYLISOLEUCYLTYROSINE; GLYCYLALANYLGLYCYLHYDROXYPROLYLPROLYLISOLEUCYLTYROSINE; GLYCYLALANYLGLYCYLHYDROXYPROLYLPROLYLPHENYLALANINE; GLYCYLALANYLGLYCYLHYDROXYPROLYLPROLYLPHENYLALANYLTYROSINE; GLYCYLALANYLGLYCYLHYDROXYPROLYLPROLYLTYROSINE; GLYCYLALANYLGLYCYLPROLYLPROLYLTYROSINE; GLYCYLPROLYLHYDROXYPYROLYLGLYCYLALANYLGLYCINE; GLYCYLSERYLGLYCYLHYDROXYPYOLYLPROLYLTYROSINE; UNCLASSIFIED DRUG; VALYLALANYLGLYCYLHYDROXYPROLYLPROLYLTYROSINE;

ACTION POTENTIAL; AMINO ACID SEQUENCE; ANIMAL MODEL; ANIMAL TISSUE; ANTIARRHYTHMIC ACTIVITY; ARTICLE; CONTROLLED STUDY; DRUG ISOLATION; DRUG SYNTHESIS; EPICARDIUM; HEART ARRHYTHMIA; HEART ATRIUM; HEART MUSCLE POTENTIAL; ISCHEMIA; ISOLATED HEART; MOLECULAR MODEL; MOLECULE; MUTATION; NONHUMAN; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

ANIMALS; ANTI-ARRHYTHMIA AGENTS; CATTLE; COMPUTER SIMULATION; DOSE-RESPONSE RELATIONSHIP, DRUG; HEART ATRIA; ISCHEMIA; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MODELS, CHEMICAL; MODELS, MOLECULAR; MODELS, THEORETICAL; MUTATION; MYOCARDIUM; OLIGOPEPTIDES; PEPTIDES; PERICARDIUM; POTASSIUM; PROTEIN CONFORMATION; RABBITS; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS; WATER;

EID: 0034968994     PISSN: 01969781     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0196-9781(01)00419-3     Document Type: Article

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