Unique and shared functions of different connexins in mice

Current Biology

Volumn 10, Issue 18, 2000, Pages 1083-1091

  Plum, A ^a,f   Hallas, G ^a   Magin, T ^a   Dombrowski, F ^a   Hagendorff, A ^b   Schumacher, B ^c   Wolpert, C ^a   Kim, J S ^d   Lamers, W H ^d   Evert, M ^a   Meda, P ^e   Traub, O ^a   Willecke, K ^a  

^a UNIVERSITY OF BONN   (Germany)

^b UNIVERSITY OF LEIPZIG   (Germany)

^c Medizinische Klinik II   (Germany)

^d UNIVERSITY OF AMSTERDAM   (Netherlands)

^e UNIVERSITY OF GENEVA   (Switzerland)

^f Mice/More   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 0034699350     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(00)00690-4     Document Type: Article

References (41)

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2. Molecular biology of the interactions between connexins
3. Molecular cloning and functional expression of the mouse gap junction gene connexin-57 in human HeLa cells
4. Gap junctions: New tools, new answers, new questions
5. Genetic diseases and gene knockouts reveal diverse connexin functions
6. Biological functions of connexin genes revealed by human genetic defects, dominant negative approaches and targeted deletions in the mouse
7. Spatial distribution of connexin43, the major cardiac gap junction protein, visualizes the cellular network for impulse propagation from sinoatrial node to atrium
8. Defects in the germ line and gonads of mice lacking connexin43
9. Cardiac malformation in neonatal mice lacking connexin43
10. Two homologous protein components of hepatic gap junctions
11. Connexin mutations in X-linked Charcot-Marie-Tooth disease
12. Developmental regulation of connexin 40 gene expression in mouse heart correlates with the differentiation of the conduction system
13. Connexin 43 and connexin 40 gap junctional proteins are present in arteriolar smooth muscle and endothelium in vivo
14. Connexin45 (alpha 6) expression delineates an extended conduction system in the embryonic and mature rodent heart
15. Formation of heterotypic gap junction channels by connexins 40 and 43
16. Reduced cardiac conduction velocity and predisposition to arrhythmias in connexin40-deficient mice
17. Mice lacking connexin40 have cardiac conduction abnormalities characteristic of atrioventricular block and bundle branch block
18. Size and selectivity of gap junction channels formed from different connexins
19. A structural basis for the unequal sensitivity of the major cardiac and liver gap junctions to intracellular acidification: The carboxyl tail length
20. Direct association of the gap junction protein connexin-43 with ZO-1 in cardiac myocytes
21. Structural changes in lenses of mice lacking the gap junction protein connexin43
22. Analysis of multiple gap junction gene products in the rodent and human mammary gland
23. Changes in the phosphorylation states of connexin43 in myoepithelial cells of lactating rat mammary glands
24. Oxytocin is required for nursing but is not essential for parturition or reproductive behavior
25. Connexin 32 mRNA levels in the rat supraoptic nucleus: Up-regulation prior to parturition and during lactation
26. Identification of two further gap-junctional proteins, connexin40 and connexin45, in human myometrial smooth muscle cells at term
27. Cell-, age- and stage-dependent distribution of connexin43 gap junctions in testes
28. Coexpression of gap junction proteins in the cumulus-oocyte complex
29. Alteration in connexin 43 gap junction gene dosage impairs conotruncal heart development
30. Gap junction-mediated cell-cell communication modulates mouse neural crest migration
31. Conduction disturbances and increased atrial vulnerability in Connexin40-deficient mice analyzed by transesophageal stimulation
32. Characterization of conduction in the ventricles of normal and heterozygous Cx43 knockout mice using optical mapping
33. Slow ventricular conduction in mice heterozygous for a connexin43 null mutation
34. Connexins in mammalian heart function
35. Accelerated onset and increased incidence of ventricular arrhythmias induced by ischemia in Cx43-deficient mice
36. Coexpression of connexin40 and 43 enhances the pH sensitivity of gap junctions: A model for synergistic interactions among connexins
37. Hetero-domain interactions as a mechanism for the regulation of connexin channels
38. Molecular cloning and functional expression of mouse connexin40, a second gap junction gene preferentially expressed in lung
39. Molecular cloning of mouse connexins26 and -32: Similar genomic organization but distinct promoter sequences of two gap junction genes
40. General or cell-type specific deletion and replacement of connexin coding DNA in the mouse