-
1
-
-
33846422032
-
Obesity and diabetes in the developing world--a growing challenge
-
Hossain P, Kawar B, El Nahas M. Obesity and diabetes in the developing world--a growing challenge. N Engl J Med 2007; 356: 213-5.
-
(2007)
N Engl J Med
, vol.356
, pp. 213-215
-
-
Hossain, P.1
Kawar, B.2
El Nahas, M.3
-
2
-
-
19944390213
-
Pathogenesis of Type 2 Diabetes Mellitus
-
Leahy JL. Pathogenesis of Type 2 Diabetes Mellitus. Arch Med Res 2005; 36: 197-209.
-
(2005)
Arch Med Res
, vol.36
, pp. 197-209
-
-
Leahy, J.L.1
-
4
-
-
33745863033
-
Islet beta cell failure in type 2 diabetes
-
Prentki M, Nolan CJ. Islet beta cell failure in type 2 diabetes. J Clin Invest 2006; 116: 1802-12.
-
(2006)
J Clin Invest
, vol.116
, pp. 1802-1812
-
-
Prentki, M.1
Nolan, C.J.2
-
5
-
-
50049086521
-
The emerging genetic architecture of type 2 diabetes
-
Doria A, Patti ME, Kahn CR. The emerging genetic architecture of type 2 diabetes. Cell Metab 2008; 8: 186-200.
-
(2008)
Cell Metab
, vol.8
, pp. 186-200
-
-
Doria, A.1
Patti, M.E.2
Kahn, C.R.3
-
6
-
-
0026110135
-
Banting lecture 1990. Beta-cells in type II diabetes mellitus
-
Porte D, Jr. Banting lecture 1990. Beta-cells in type II diabetes mellitus. Diabetes 1991; 40: 166-80.
-
(1991)
Diabetes
, vol.40
, pp. 166-180
-
-
Porte Jr., D.1
-
7
-
-
0036896505
-
Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: Role in beta-cell adaptation and failure in the etiology of diabetes
-
Prentki M, Joly E, El-Assaad W, Roduit R. Malonyl-CoA signaling, lipid partitioning, and glucolipotoxicity: role in beta-cell adaptation and failure in the etiology of diabetes. Diabetes 2002; 51 Suppl 3: S405-13.
-
(2002)
Diabetes
, vol.51
, Issue.SUPPL 3
-
-
Prentki, M.1
Joly, E.2
El-Assaad, W.3
Roduit, R.4
-
8
-
-
0035130272
-
Betacell adaptation and decompensation during the progression of diabetes
-
Weir GC, Laybutt DR, Kaneto H, Bonner-Weir S, Sharma A. Betacell adaptation and decompensation during the progression of diabetes. Diabetes 2001; 50 Suppl 1: S154-9.
-
(2001)
Diabetes
, vol.50
, Issue.SUPPL 1
-
-
Weir, G.C.1
Laybutt, D.R.2
Kaneto, H.3
Bonner-Weir, S.4
Sharma, A.5
-
9
-
-
66649125230
-
Advanced Glycation End Products Inhibit Glucose-Stimulated Insulin Secretion through Nitric Oxide-Dependent Inhibition of Cytochrome c Oxidase and Adenosine Triphosphate Synthesis
-
Zhao Z, Zhao C, Zhang XH, et al. Advanced Glycation End Products Inhibit Glucose-Stimulated Insulin Secretion through Nitric Oxide-Dependent Inhibition of Cytochrome c Oxidase and Adenosine Triphosphate Synthesis. Endocrinology 2009; 150: 2569-76.
-
(2009)
Endocrinology
, vol.150
, pp. 2569-2576
-
-
Zhao, Z.1
Zhao, C.2
Zhang, X.H.3
-
10
-
-
61449123871
-
Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis
-
Zraika S, Hull RL, Udayasankar J, et al. Oxidative stress is induced by islet amyloid formation and time-dependently mediates amyloid-induced beta cell apoptosis. Diabetologia 2009; 52: 626-35.
-
(2009)
Diabetologia
, vol.52
, pp. 626-635
-
-
Zraika, S.1
Hull, R.L.2
Udayasankar, J.3
-
11
-
-
77953957172
-
The beta-cell in human type 2 diabetes
-
Marchetti P, Lupi R, Del Guerra S, Bugliani M, Marselli L, Boggi U. The beta-cell in human type 2 diabetes. Adv Exp Med Biol 2010; 654: 501-14.
-
(2010)
Adv Exp Med Biol
, vol.654
, pp. 501-514
-
-
Marchetti, P.1
Lupi, R.2
del Guerra, S.3
Bugliani, M.4
Marselli, L.5
Boggi, U.6
-
12
-
-
77956584167
-
Targeting betacell function early in the course of therapy for type 2 diabetes mellitus
-
Leahy JL, Hirsch IB, Peterson KA, Schneider D. Targeting betacell function early in the course of therapy for type 2 diabetes mellitus. J Clin Endocrinol Metab 2010; 95: 4206-16.
-
(2010)
J Clin Endocrinol Metab
, vol.95
, pp. 4206-4216
-
-
Leahy, J.L.1
Hirsch, I.B.2
Peterson, K.A.3
Schneider, D.4
-
13
-
-
79151478555
-
Type 2 diabetes as an inflammatory disease
-
Donath MY, Shoelson SE. Type 2 diabetes as an inflammatory disease. Nat Rev Immunol 2011; 11: 98-107.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 98-107
-
-
Donath, M.Y.1
Shoelson, S.E.2
-
14
-
-
10944265062
-
Free Fatty Acid-induced {beta}-Cell Defects Are Dependent on Uncoupling Protein 2 Expression
-
Joseph JW, Koshkin V, Saleh MC, et al. Free Fatty Acid-induced {beta}-Cell Defects Are Dependent on Uncoupling Protein 2 Expression. J Biol Chem 2004; 279: 51049-56.
-
(2004)
J Biol Chem
, vol.279
, pp. 51049-51056
-
-
Joseph, J.W.1
Koshkin, V.2
Saleh, M.C.3
-
15
-
-
0842284799
-
Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes
-
Robertson RP, Harmon J, Tran PO, Poitout V. Beta-cell glucose toxicity, lipotoxicity, and chronic oxidative stress in type 2 diabetes. Diabetes 2004; 53 Suppl 1: S119-24.
-
(2004)
Diabetes
, vol.53
, Issue.SUPPL 1
-
-
Robertson, R.P.1
Harmon, J.2
Tran, P.O.3
Poitout, V.4
-
16
-
-
12344305124
-
Mitochondrial dysfunction and type 2 diabetes
-
Lowell BB, Shulman GI. Mitochondrial dysfunction and type 2 diabetes. Science 2005; 307: 384-7.
-
(2005)
Science
, vol.307
, pp. 384-387
-
-
Lowell, B.B.1
Shulman, G.I.2
-
17
-
-
33644747390
-
Mechanisms of beta-cell death in type 2 diabetes
-
Donath MY, Ehses JA, Maedler K, et al. Mechanisms of beta-cell death in type 2 diabetes. Diabetes 2005; 54: S108-13.
-
(2005)
Diabetes
, vol.54
-
-
Donath, M.Y.1
Ehses, J.A.2
Maedler, K.3
-
18
-
-
33645765312
-
Diabetes and mitochondrial function: Role of hyperglycemia and oxidative stress
-
Rolo AP, Palmeira CM. Diabetes and mitochondrial function: role of hyperglycemia and oxidative stress. Toxicol Appl Pharmacol 2006; 212: 167-78.
-
(2006)
Toxicol Appl Pharmacol
, vol.212
, pp. 167-178
-
-
Rolo, A.P.1
Palmeira, C.M.2
-
19
-
-
68349119363
-
Diabetes, oxidative stress, nitric oxide and mitochondria function
-
Friederich M, Hansell P, Palm F. Diabetes, oxidative stress, nitric oxide and mitochondria function. Curr Diabetes Rev 2009; 5: 120-44.
-
(2009)
Curr Diabetes Rev
, vol.5
, pp. 120-144
-
-
Friederich, M.1
Hansell, P.2
Palm, F.3
-
20
-
-
0036163156
-
Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients
-
Sakuraba H, Mizukami H, Yagihashi N, Wada R, Hanyu C, Yagihashi S. Reduced beta-cell mass and expression of oxidative stress-related DNA damage in the islet of Japanese Type II diabetic patients. Diabetologia 2002; 45: 85-96.
-
(2002)
Diabetologia
, vol.45
, pp. 85-96
-
-
Sakuraba, H.1
Mizukami, H.2
Yagihashi, N.3
Wada, R.4
Hanyu, C.5
Yagihashi, S.6
-
21
-
-
8744272467
-
Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin
-
Marchetti P, Del Guerra S, Marselli L, et al. Pancreatic islets from type 2 diabetic patients have functional defects and increased apoptosis that are ameliorated by metformin. J Clin Endocrinol Metab 2004; 89: 5535-41.
-
(2004)
J Clin Endocrinol Metab
, vol.89
, pp. 5535-5541
-
-
Marchetti, P.1
del Guerra, S.2
Marselli, L.3
-
22
-
-
5644248079
-
Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes
-
Robertson RP. Chronic oxidative stress as a central mechanism for glucose toxicity in pancreatic islet beta cells in diabetes. J Biol Chem 2004; 279: 42351-4.
-
(2004)
J Biol Chem
, vol.279
, pp. 42351-42354
-
-
Robertson, R.P.1
-
23
-
-
25844520458
-
Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism
-
Jezek P, Hlavata L. Mitochondria in homeostasis of reactive oxygen species in cell, tissues, and organism. Int J Biochem Cell Biol 2005; 37: 2478-503.
-
(2005)
Int J Biochem Cell Biol
, vol.37
, pp. 2478-2503
-
-
Jezek, P.1
Hlavata, L.2
-
24
-
-
69949160564
-
Redox mechanisms in hepatic chronic wound healing and fibrogenesis
-
Novo E, Parola M. Redox mechanisms in hepatic chronic wound healing and fibrogenesis. Fibrogenesis Tissue Repair 2008; 1: 5.
-
(2008)
Fibrogenesis Tissue Repair
, vol.1
, pp. 5
-
-
Novo, E.1
Parola, M.2
-
25
-
-
43549108142
-
Glucolipotoxicity: Fuel excess and betacell dysfunction
-
Poitout V, Robertson RP. Glucolipotoxicity: fuel excess and betacell dysfunction. Endocr Rev 2008; 29: 351-66.
-
(2008)
Endocr Rev
, vol.29
, pp. 351-366
-
-
Poitout, V.1
Robertson, R.P.2
-
26
-
-
0141815741
-
Production of Reactive Oxygen Species by Mitochondria: Central role of complex III
-
Chen Q, Vazquez EJ, Moghaddas S, Hoppel CL, Lesnefsky EJ. Production of Reactive Oxygen Species by Mitochondria: Central role of complex III. J Biol Chem 2003; 278: 36027-31.
-
(2003)
J Biol Chem
, vol.278
, pp. 36027-36031
-
-
Chen, Q.1
Vazquez, E.J.2
Moghaddas, S.3
Hoppel, C.L.4
Lesnefsky, E.J.5
-
27
-
-
0035856942
-
Mitochondrial function in normal and diabetic beta-cells
-
Maechler P, Wollheim CB. Mitochondrial function in normal and diabetic beta-cells. Nature 2001; 414: 807-12.
-
(2001)
Nature
, vol.414
, pp. 807-812
-
-
Maechler, P.1
Wollheim, C.B.2
-
28
-
-
17844403964
-
Role of mitochondria in toxic oxidative stress
-
Fariss MW, Chan CB, Patel M, Van Houten B, Orrenius S. Role of mitochondria in toxic oxidative stress. Mol Interv 2005; 5: 94-111.
-
(2005)
Mol Interv
, vol.5
, pp. 94-111
-
-
Fariss, M.W.1
Chan, C.B.2
Patel, M.3
van Houten, B.4
Orrenius, S.5
-
29
-
-
33746268123
-
Characterization of cardiolipin as the sodiated ions by positive-ion electrospray ionization with multiple stage quadrupole ion-trap mass spectrometry
-
Hsu FF, Turk J. Characterization of cardiolipin as the sodiated ions by positive-ion electrospray ionization with multiple stage quadrupole ion-trap mass spectrometry. J Am Soc Mass Spectrom 2006; 17: 1146-57.
-
(2006)
J Am Soc Mass Spectrom
, vol.17
, pp. 1146-1157
-
-
Hsu, F.F.1
Turk, J.2
-
30
-
-
15744378826
-
Structural characterization of cardiolipin by tandem quadrupole and multiple-stage quadrupole ion-trap mass spectrometry with electrospray ionization
-
Hsu FF, Turk J, Rhoades ER, Russell DG, Shi Y, Groisman EA. Structural characterization of cardiolipin by tandem quadrupole and multiple-stage quadrupole ion-trap mass spectrometry with electrospray ionization. J Am Soc Mass Spectrom 2005; 16: 491-504.
-
(2005)
J Am Soc Mass Spectrom
, vol.16
, pp. 491-504
-
-
Hsu, F.F.1
Turk, J.2
Rhoades, E.R.3
Russell, D.G.4
Shi, Y.5
Groisman, E.A.6
-
31
-
-
29244477536
-
Shotgun lipidomics identifies cardiolipin depletion in diabetic myocardium linking altered substrate utilization with mitochondrial dysfunction
-
Han X, Yang J, Cheng H, Yang K, Abendschein DR, Gross RW. Shotgun lipidomics identifies cardiolipin depletion in diabetic myocardium linking altered substrate utilization with mitochondrial dysfunction. Biochemistry 2005; 44: 16684-94.
-
(2005)
Biochemistry
, vol.44
, pp. 16684-16694
-
-
Han, X.1
Yang, J.2
Cheng, H.3
Yang, K.4
Abendschein, D.R.5
Gross, R.W.6
-
32
-
-
34249672811
-
Alterations in myocardial cardiolipin content and composition occur at the very earliest stages of diabetes: A shotgun lipidomics study
-
Han X, Yang J, Yang K, Zhao Z, Abendschein DR, Gross RW. Alterations in myocardial cardiolipin content and composition occur at the very earliest stages of diabetes: a shotgun lipidomics study. Biochemistry 2007; 46: 6417-28.
-
(2007)
Biochemistry
, vol.46
, pp. 6417-6428
-
-
Han, X.1
Yang, J.2
Yang, K.3
Zhao, Z.4
Abendschein, D.R.5
Gross, R.W.6
-
33
-
-
0037219411
-
Beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes
-
Butler AE, Janson J, Bonner-Weir S, Ritzel R, Rizza RA, Butler PC. beta-cell deficit and increased beta-cell apoptosis in humans with type 2 diabetes. Diabetes 2003; 52: 102-10.
-
(2003)
Diabetes
, vol.52
, pp. 102-110
-
-
Butler, A.E.1
Janson, J.2
Bonner-Weir, S.3
Ritzel, R.4
Rizza, R.A.5
Butler, P.C.6
-
34
-
-
12344323484
-
Type 2 diabetes-a matter of beta-cell life and death?
-
Rhodes CJ. Type 2 diabetes-a matter of beta-cell life and death? Science 2005; 307: 380-4.
-
(2005)
Science
, vol.307
, pp. 380-384
-
-
Rhodes, C.J.1
-
35
-
-
1842767259
-
Mitochondrial regulation of apoptotic cell death
-
Orrenius S. Mitochondrial regulation of apoptotic cell death. Toxicol Lett 2004; 149: 19-23.
-
(2004)
Toxicol Lett
, vol.149
, pp. 19-23
-
-
Orrenius, S.1
-
36
-
-
3943071150
-
Cytochrome C-Mediated Apoptosis
-
Jiang X, Wang X. Cytochrome C-Mediated Apoptosis. Annu Rev Biochem 2004; 73: 87-106.
-
(2004)
Annu Rev Biochem
, vol.73
, pp. 87-106
-
-
Jiang, X.1
Wang, X.2
-
37
-
-
27744433524
-
Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors
-
Kagan VE, Tyurin VA, Jiang J, et al. Cytochrome c acts as a cardiolipin oxygenase required for release of proapoptotic factors. Nat Chem Biol 2005; 1: 223-32.
-
(2005)
Nat Chem Biol
, vol.1
, pp. 223-232
-
-
Kagan, V.E.1
Tyurin, V.A.2
Jiang, J.3
-
38
-
-
33746298246
-
Mechanisms of cytochrome c release from mitochondria
-
Garrido C, Galluzzi L, Brunet M, Puig PE, Didelot C, Kroemer G. Mechanisms of cytochrome c release from mitochondria. Cell Death Differ 2006; 13: 1423-33.
-
(2006)
Cell Death Differ
, vol.13
, pp. 1423-1433
-
-
Garrido, C.1
Galluzzi, L.2
Brunet, M.3
Puig, P.E.4
Didelot, C.5
Kroemer, G.6
-
39
-
-
50249148905
-
Cardiolipin, the heart of mitochondrial metabolism
-
Houtkooper RH, Vaz FM. Cardiolipin, the heart of mitochondrial metabolism. Cell Mol Life Sci 2008; 65: 2493-506.
-
(2008)
Cell Mol Life Sci
, vol.65
, pp. 2493-2506
-
-
Houtkooper, R.H.1
Vaz, F.M.2
-
40
-
-
70349518563
-
Cardiolipin and mitochondrial carriers
-
Klingenberg M. Cardiolipin and mitochondrial carriers. Biochim Biophys Acta 2009; 1788: 2048-58.
-
(2009)
Biochim Biophys Acta
, vol.1788
, pp. 2048-2058
-
-
Klingenberg, M.1
-
41
-
-
33644828424
-
Cardiolipin oxidation sets cytochrome c free
-
Orrenius S, Zhivotovsky B. Cardiolipin oxidation sets cytochrome c free. Nat Chem Biol 2005; 1: 188-9.
-
(2005)
Nat Chem Biol
, vol.1
, pp. 188-189
-
-
Orrenius, S.1
Zhivotovsky, B.2
-
42
-
-
0034193996
-
The biosynthesis and functional role of cardiolipin
-
Schlame M, Rua D, Greenberg ML. The biosynthesis and functional role of cardiolipin. Prog Lipid Res 2000; 39: 257-88.
-
(2000)
Prog Lipid Res
, vol.39
, pp. 257-288
-
-
Schlame, M.1
Rua, D.2
Greenberg, M.L.3
-
43
-
-
0023037212
-
Glucose-induced phospholipid hydrolysis in isolated pancreatic islets: Quantitative effects on the phospholipid content of arachidonate and other fatty acids
-
Turk J, Wolf BA, Lefkowith JB, Stump WT, McDaniel ML. Glucose-induced phospholipid hydrolysis in isolated pancreatic islets: quantitative effects on the phospholipid content of arachidonate and other fatty acids. Biochim Biophys Acta 1986; 879: 399-409.
-
(1986)
Biochim Biophys Acta
, vol.879
, pp. 399-409
-
-
Turk, J.1
Wolf, B.A.2
Lefkowith, J.B.3
Stump, W.T.4
McDaniel, M.L.5
-
44
-
-
0036547417
-
Death and anti-death: Tumour resistance to apoptosis
-
Igney FH, Krammer PH. Death and anti-death: tumour resistance to apoptosis. Nat Rev Cancer 2002; 2: 277-88.
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 277-288
-
-
Igney, F.H.1
Krammer, P.H.2
-
45
-
-
78049407128
-
Cardiolipin remodeling by ALCAT1 links oxidative stress and mitochondrial dysfunction to obesity
-
Li J, Romestaing C, Han X, et al. Cardiolipin remodeling by ALCAT1 links oxidative stress and mitochondrial dysfunction to obesity. Cell Metab 2010; 12: 154-65.
-
(2010)
Cell Metab
, vol.12
, pp. 154-165
-
-
Li, J.1
Romestaing, C.2
Han, X.3
-
46
-
-
77953583649
-
Altered mitochondrial membrane potential, mass, and morphology in the mononuclear cells of humans with type 2 diabetes
-
Widlansky ME, Wang J, Shenouda SM, et al. Altered mitochondrial membrane potential, mass, and morphology in the mononuclear cells of humans with type 2 diabetes. Transl Res 2010; 156: 15-25.
-
(2010)
Transl Res
, vol.156
, pp. 15-25
-
-
Widlansky, M.E.1
Wang, J.2
Shenouda, S.M.3
-
47
-
-
77954576363
-
2-Mediated Repair of Mitochondrial Membrane Peroxidation
-
2-Mediated Repair of Mitochondrial Membrane Peroxidation. Endocrinology 2010; 151: 3038-48.
-
(2010)
Endocrinology
, vol.151
, pp. 3038-3048
-
-
Zhao, Z.1
Zhang, X.2
Zhao, C.3
-
48
-
-
33846272138
-
Role of cardiolipin alterations in mitochondrial dysfunction and disease
-
Chicco AJ, Sparagna GC. Role of cardiolipin alterations in mitochondrial dysfunction and disease. Am J Physiol Cell Physiol 2007; 292: C33-44.
-
(2007)
Am J Physiol Cell Physiol
, vol.292
-
-
Chicco, A.J.1
Sparagna, G.C.2
-
49
-
-
34247482333
-
Cardiolipin: Setting the beat of apoptosis
-
Gonzalvez F, Gottlieb E. Cardiolipin: setting the beat of apoptosis. Apoptosis 2007; 12: 877-85.
-
(2007)
Apoptosis
, vol.12
, pp. 877-885
-
-
Gonzalvez, F.1
Gottlieb, E.2
-
50
-
-
46449083451
-
Oxidative stress and mitochondrial dysfunction in neurodegeneration; cardiolipin a critical target?
-
Pope S, Land JM, Heales SJ. Oxidative stress and mitochondrial dysfunction in neurodegeneration; cardiolipin a critical target? Biochim Biophys Acta 2008; 1777: 794-9.
-
(2008)
Biochim Biophys Acta
, vol.1777
, pp. 794-799
-
-
Pope, S.1
Land, J.M.2
Heales, S.J.3
-
51
-
-
74549206782
-
Degradation of phospholipids by oxidative stress--exceptional significance of cardiolipin
-
Wiswedel I, Gardemann A, Storch A, Peter D, Schild L. Degradation of phospholipids by oxidative stress--exceptional significance of cardiolipin. Free Radic Res 2010; 44: 135-45.
-
(2010)
Free Radic Res
, vol.44
, pp. 135-145
-
-
Wiswedel, I.1
Gardemann, A.2
Storch, A.3
Peter, D.4
Schild, L.5
-
52
-
-
33746836946
-
2 Localizes in and Protects Mitochondria during Apoptotic Induction by Staurosporine
-
2 Localizes in and Protects Mitochondria during Apoptotic Induction by Staurosporine. J Biol Chem 2006; 281: 22275-88.
-
(2006)
J Biol Chem
, vol.281
, pp. 22275-22288
-
-
Seleznev, K.1
Zhao, C.2
Zhang, X.H.3
Song, K.4
Ma, Z.A.5
-
53
-
-
0028057533
-
Enzymatic, metabolic and secretory patterns in human islets of type 2 (non-insulin-dependent) diabetic patients
-
Fernandez-Alvarez J, Conget I, Rasschaert J, Sener A, Gomis R, Malaisse WJ. Enzymatic, metabolic and secretory patterns in human islets of type 2 (non-insulin-dependent) diabetic patients. Diabetologia 1994; 37: 177-81.
-
(1994)
Diabetologia
, vol.37
, pp. 177-181
-
-
Fernandez-Alvarez, J.1
Conget, I.2
Rasschaert, J.3
Sener, A.4
Gomis, R.5
Malaisse, W.J.6
-
54
-
-
10744222060
-
Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects
-
Deng S, Vatamaniuk M, Huang X, et al. Structural and functional abnormalities in the islets isolated from type 2 diabetic subjects. Diabetes 2004; 53: 624-32.
-
(2004)
Diabetes
, vol.53
, pp. 624-632
-
-
Deng, S.1
Vatamaniuk, M.2
Huang, X.3
-
55
-
-
0031892853
-
Pancreatic beta-cell glucokinase: Closing the gap between theoretical concepts and experimental realities
-
Matschinsky FM, Glaser B, Magnuson MA. Pancreatic beta-cell glucokinase: closing the gap between theoretical concepts and experimental realities. Diabetes 1998; 47: 307-15.
-
(1998)
Diabetes
, vol.47
, pp. 307-315
-
-
Matschinsky, F.M.1
Glaser, B.2
Magnuson, M.A.3
-
56
-
-
0035875087
-
Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes
-
Zhang CY, Baffy G, Perret P, et al. Uncoupling protein-2 negatively regulates insulin secretion and is a major link between obesity, beta cell dysfunction, and type 2 diabetes. Cell 2001; 105: 745-55.
-
(2001)
Cell
, vol.105
, pp. 745-755
-
-
Zhang, C.Y.1
Baffy, G.2
Perret, P.3
-
57
-
-
0035875066
-
The pancreatic beta cell heats up: UCP2 and insulin secretion in diabetes
-
Polonsky KS, Semenkovich CF. The pancreatic beta cell heats up: UCP2 and insulin secretion in diabetes. Cell 2001; 105: 705-7.
-
(2001)
Cell
, vol.105
, pp. 705-707
-
-
Polonsky, K.S.1
Semenkovich, C.F.2
-
58
-
-
0036724133
-
Role of ATP Production and Uncoupling Protein-2 in the Insulin Secretory Defect Induced by Chronic Exposure to High Glucose or Free Fatty Acids and Effects of Peroxisome Proliferator-Activated Receptor-gamma Inhibition
-
Patane G, Anello M, Piro S, Vigneri R, Purrello F, Rabuazzo AM. Role of ATP Production and Uncoupling Protein-2 in the Insulin Secretory Defect Induced by Chronic Exposure to High Glucose or Free Fatty Acids and Effects of Peroxisome Proliferator-Activated Receptor-gamma Inhibition. Diabetes 2002; 51: 2749-56.
-
(2002)
Diabetes
, vol.51
, pp. 2749-2756
-
-
Patane, G.1
Anello, M.2
Piro, S.3
Vigneri, R.4
Purrello, F.5
Rabuazzo, A.M.6
-
59
-
-
18244379331
-
Superoxide activates mitochondrial uncoupling proteins
-
Echtay KS, Roussel D, St-Pierre J, et al. Superoxide activates mitochondrial uncoupling proteins. Nature 2002; 415: 96-9.
-
(2002)
Nature
, vol.415
, pp. 96-99
-
-
Echtay, K.S.1
Roussel, D.2
St-Pierre, J.3
-
60
-
-
0037033039
-
Superoxide Activates Mitochondrial Uncoupling Protein 2 from the Matrix Side. Studies using targeted antioxidants
-
Echtay KS, Murphy MP, Smith RAJ, Talbot DA, Brand MD. Superoxide Activates Mitochondrial Uncoupling Protein 2 from the Matrix Side. Studies using targeted antioxidants. J Biol Chem 2002; 277: 47129-35.
-
(2002)
J Biol Chem
, vol.277
, pp. 47129-47135
-
-
Echtay, K.S.1
Murphy, M.P.2
Smith, R.A.J.3
Talbot, D.A.4
Brand, M.D.5
-
61
-
-
0346340042
-
Superoxide-mediated activation of uncoupling protein 2 causes pancreatic beta cell dysfunction
-
Krauss S, Zhang C-Y, Scorrano L, et al. Superoxide-mediated activation of uncoupling protein 2 causes pancreatic beta cell dysfunction. J Clin Invest 2003; 112: 1831-42.
-
(2003)
J Clin Invest
, vol.112
, pp. 1831-1842
-
-
Krauss, S.1
Zhang, C-Y.2
Scorrano, L.3
-
62
-
-
33947618988
-
Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action
-
De Souza CT, Araujo EP, Stoppiglia LF, et al. Inhibition of UCP2 expression reverses diet-induced diabetes mellitus by effects on both insulin secretion and action. FASEB J 2007; 21: 1153-63.
-
(2007)
FASEB J
, vol.21
, pp. 1153-1163
-
-
de Souza, C.T.1
Araujo, E.P.2
Stoppiglia, L.F.3
-
63
-
-
33744548069
-
Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity-and high glucose-induced beta cell dysfunction in isolated pancreatic islets
-
Zhang CY, Parton LE, Ye CP, et al. Genipin inhibits UCP2-mediated proton leak and acutely reverses obesity-and high glucose-induced beta cell dysfunction in isolated pancreatic islets. Cell Metab 2006; 3: 417-27.
-
(2006)
Cell Metab
, vol.3
, pp. 417-427
-
-
Zhang, C.Y.1
Parton, L.E.2
Ye, C.P.3
-
64
-
-
0346814090
-
Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: Studies using a mitochondria-targeted spin trap derived from alpha-phenyl-N-tert-butylnitrone
-
Murphy MP, Echtay KS, Blaikie FH, et al. Superoxide activates uncoupling proteins by generating carbon-centered radicals and initiating lipid peroxidation: studies using a mitochondria-targeted spin trap derived from alpha-phenyl-N-tert-butylnitrone. J Biol Chem 2003; 278: 48534-45.
-
(2003)
J Biol Chem
, vol.278
, pp. 48534-48545
-
-
Murphy, M.P.1
Echtay, K.S.2
Blaikie, F.H.3
-
65
-
-
25144476923
-
Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3
-
Brand MD, Esteves TC. Physiological functions of the mitochondrial uncoupling proteins UCP2 and UCP3. Cell Metab 2005; 2: 85-93.
-
(2005)
Cell Metab
, vol.2
, pp. 85-93
-
-
Brand, M.D.1
Esteves, T.C.2
-
66
-
-
78650708296
-
Formation of 4-hydroxynonenal from cardiolipin oxidation: Intramolecular peroxyl radical addition and decomposition
-
Liu W, Porter NA, Schneider C, Brash AR, Yin H. Formation of 4-hydroxynonenal from cardiolipin oxidation: Intramolecular peroxyl radical addition and decomposition. Free Radic Biol Med 2011; 50: 166-78.
-
(2011)
Free Radic Biol Med
, vol.50
, pp. 166-178
-
-
Liu, W.1
Porter, N.A.2
Schneider, C.3
Brash, A.R.4
Yin, H.5
-
67
-
-
33750502270
-
Oxidative stress and impaired insulin secretion in type 2 diabetes
-
Robertson RP. Oxidative stress and impaired insulin secretion in type 2 diabetes. Curr Opin Pharmacol 2006; 6: 615-9.
-
(2006)
Curr Opin Pharmacol
, vol.6
, pp. 615-619
-
-
Robertson, R.P.1
-
68
-
-
0037341238
-
Glucose Toxicity in beta-Cells: Type 2 Diabetes, Good Radicals Gone Bad, and the Glutathione Connection
-
Robertson RP, Harmon J, Tran PO, Tanaka Y, Takahashi H. Glucose Toxicity in beta-Cells: Type 2 Diabetes, Good Radicals Gone Bad, and the Glutathione Connection. Diabetes 2003; 52: 581-7.
-
(2003)
Diabetes
, vol.52
, pp. 581-587
-
-
Robertson, R.P.1
Harmon, J.2
Tran, P.O.3
Tanaka, Y.4
Takahashi, H.5
-
69
-
-
0022328960
-
2 and glutathione peroxidase is required for reduction of phospholipid hydroperoxides and provides a convenient method to determine peroxide values in membranes
-
2 and glutathione peroxidase is required for reduction of phospholipid hydroperoxides and provides a convenient method to determine peroxide values in membranes. J Free Radic Biol Med 1985; 1: 421-7.
-
(1985)
J Free Radic Biol Med
, vol.1
, pp. 421-427
-
-
van Kuijk, F.J.1
Handelman, G.J.2
Dratz, E.A.3
-
70
-
-
0037438730
-
Biological significance of phospholipid hydroperoxide glutathione peroxidase (PHGPx, GPx4) in mammalian cells
-
Imai H, Nakagawa Y. Biological significance of phospholipid hydroperoxide glutathione peroxidase (PHGPx, GPx4) in mammalian cells. Free Radic Biol Med 2003; 34: 145-69.
-
(2003)
Free Radic Biol Med
, vol.34
, pp. 145-169
-
-
Imai, H.1
Nakagawa, Y.2
-
73
-
-
0012511289
-
Sevanian A Lipid damage and repair
-
In, Davies K, Ed. New York, Pergamon Press
-
Sevanian A Lipid damage and repair. In Oxidative Damage and Repair Davies K, Ed. New York, Pergamon Press, 1988, p. 543-9.
-
(1988)
Oxidative Damage and Repair
, pp. 543-549
-
-
-
74
-
-
0021779906
-
Mechanisms and consequences of lipid peroxidation in biological systems
-
Sevanian A, Hochstein P. Mechanisms and consequences of lipid peroxidation in biological systems. Annu Rev Nutr 1985; 5: 365-90.
-
(1985)
Annu Rev Nutr
, vol.5
, pp. 365-390
-
-
Sevanian, A.1
Hochstein, P.2
-
79
-
-
2342542370
-
Cell biology of cardiac mitochondrial phospholipids
-
Hatch GM. Cell biology of cardiac mitochondrial phospholipids. Biochem Cell Biol 2004; 82: 99-112.
-
(2004)
Biochem Cell Biol
, vol.82
, pp. 99-112
-
-
Hatch, G.M.1
-
80
-
-
0029963145
-
A novel X-linked gene, G4.5. is responsible for Barth syndrome
-
Bione S, D'Adamo P, Maestrini E, Gedeon AK, Bolhuis PA, Toniolo D. A novel X-linked gene, G4.5. is responsible for Barth syndrome. Nat Genet 1996; 12: 385-9.
-
(1996)
Nat Genet
, vol.12
, pp. 385-389
-
-
Bione, S.1
D'Adamo, P.2
Maestrini, E.3
Gedeon, A.K.4
Bolhuis, P.A.5
Toniolo, D.6
-
82
-
-
0031204998
-
Barth syndrome may be due to an acyltransferase deficiency
-
Neuwald AF. Barth syndrome may be due to an acyltransferase deficiency. Curr Biol 1997; 7: R465-6.
-
(1997)
Curr Biol
, vol.7
-
-
Neuwald, A.F.1
-
83
-
-
33745553895
-
2, is mutated in neurodegenerative disorders with high brain iron
-
2, is mutated in neurodegenerative disorders with high brain iron. Nat Genet 2006; 38: 752-4.
-
(2006)
Nat Genet
, vol.38
, pp. 752-754
-
-
Morgan, N.V.1
Westaway, S.K.2
Morton, J.E.3
-
84
-
-
39549085125
-
Disrupted Membrane Homeostasis and Accumulation of Ubiquitinated Proteins in a Mouse Model of Infantile Neuroaxonal Dystrophy Caused by PLA2G6 Mutations
-
Malik I, Turk J, Mancuso DJ, et al. Disrupted Membrane Homeostasis and Accumulation of Ubiquitinated Proteins in a Mouse Model of Infantile Neuroaxonal Dystrophy Caused by PLA2G6 Mutations. Am J Pathol 2008; 172: 406-16.
-
(2008)
Am J Pathol
, vol.172
, pp. 406-416
-
-
Malik, I.1
Turk, J.2
Mancuso, D.J.3
-
85
-
-
0032496143
-
Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss
-
Cai J, Jones DP. Superoxide in apoptosis. Mitochondrial generation triggered by cytochrome c loss. J Biol Chem 1998; 273: 11401-4.
-
(1998)
J Biol Chem
, vol.273
, pp. 11401-11404
-
-
Cai, J.1
Jones, D.P.2
-
86
-
-
53549094111
-
Relationship between beta-cell mass and diabetes onset
-
Matveyenko AV, Butler PC. Relationship between beta-cell mass and diabetes onset. Diabetes Obes Metab 2008; 10 Suppl 4: 23-31.
-
(2008)
Diabetes Obes Metab
, vol.10
, Issue.SUPPL 4
, pp. 23-31
-
-
Matveyenko, A.V.1
Butler, P.C.2
-
88
-
-
39849101072
-
2 Deficiency in Mice: A Model of Human Neurodegenerative Disease
-
2 Deficiency in Mice: A Model of Human Neurodegenerative Disease. J Neurosci 2008; 28: 2212-20.
-
(2008)
J Neurosci
, vol.28
, pp. 2212-2220
-
-
Shinzawa, K.1
Sumi, H.2
Ikawa, M.3
-
89
-
-
4644235280
-
2 produce spermatozoa with impaired motility and have greatly reduced fertility
-
2 produce spermatozoa with impaired motility and have greatly reduced fertility. J Biol Chem 2004; 279: 38194-200.
-
(2004)
J Biol Chem
, vol.279
, pp. 38194-38200
-
-
Bao, S.1
Miller, D.J.2
Ma, Z.3
-
90
-
-
33746363243
-
2 and Effects of Metabolic Stress on Glucose Homeostasis
-
2 and Effects of Metabolic Stress on Glucose Homeostasis. J Biol Chem 2006; 281: 20958-73.
-
(2006)
J Biol Chem
, vol.281
, pp. 20958-20973
-
-
Bao, S.1
Song, H.2
Wohltmann, M.3
-
92
-
-
23844540312
-
Cardiolipin is essential for organization of complexes III and IV into a supercomplex in intact yeast mitochondria
-
Zhang M, Mileykovskaya E, Dowhan W. Cardiolipin is essential for organization of complexes III and IV into a supercomplex in intact yeast mitochondria. J Biol Chem 2005; 280: 29403-8.
-
(2005)
J Biol Chem
, vol.280
, pp. 29403-29408
-
-
Zhang, M.1
Mileykovskaya, E.2
Dowhan, W.3
-
93
-
-
5644225624
-
Cardiolipin biosynthesis and mitochondrial respiratory chain function are interdependent
-
Gohil VM, Hayes P, Matsuyama S, Schagger H, Schlame M, Greenberg ML. Cardiolipin biosynthesis and mitochondrial respiratory chain function are interdependent. J Biol Chem 2004; 279: 42612-8.
-
(2004)
J Biol Chem
, vol.279
, pp. 42612-42618
-
-
Gohil, V.M.1
Hayes, P.2
Matsuyama, S.3
Schagger, H.4
Schlame, M.5
Greenberg, M.L.6
-
94
-
-
61449226468
-
Mitochondrial membrane biogenesis: Phospholipids and proteins go hand in hand
-
Gohil VM, Greenberg ML. Mitochondrial membrane biogenesis: phospholipids and proteins go hand in hand. J Cell Biol 2009; 184: 469-72.
-
(2009)
J Cell Biol
, vol.184
, pp. 469-472
-
-
Gohil, V.M.1
Greenberg, M.L.2
-
97
-
-
62749103868
-
Mitochondrial reactive oxygen species are obligatory signals for glucose-induced insulin secretion
-
Leloup C, Tourrel-Cuzin C, Magnan C, et al. Mitochondrial reactive oxygen species are obligatory signals for glucose-induced insulin secretion. Diabetes 2009; 58: 673-81.
-
(2009)
Diabetes
, vol.58
, pp. 673-681
-
-
Leloup, C.1
Tourrel-Cuzin, C.2
Magnan, C.3
-
98
-
-
70349512259
-
Reactive oxygen species enhance insulin sensitivity
-
Loh K, Deng H, Fukushima A, et al. Reactive oxygen species enhance insulin sensitivity. Cell Metab 2009; 10: 260-72.
-
(2009)
Cell Metab
, vol.10
, pp. 260-272
-
-
Loh, K.1
Deng, H.2
Fukushima, A.3
-
99
-
-
4444315545
-
Supplementation of Endothelial Cells with Mitochondria-targeted Antioxidants Inhibit Peroxide-induced Mitochondrial Iron Uptake, Oxidative Damage, and Apoptosis
-
Dhanasekaran A, Kotamraju S, Kalivendi SV, et al. Supplementation of Endothelial Cells with Mitochondria-targeted Antioxidants Inhibit Peroxide-induced Mitochondrial Iron Uptake, Oxidative Damage, and Apoptosis. J Biol Chem 2004; 279: 37575-87.
-
(2004)
J Biol Chem
, vol.279
, pp. 37575-37587
-
-
Dhanasekaran, A.1
Kotamraju, S.2
Kalivendi, S.V.3
-
100
-
-
69249217642
-
Melatonin inhibits cardiolipin peroxidation in mitochondria and prevents the mitochondrial permeability transition and cytochrome c release
-
Petrosillo G, Moro N, Ruggiero FM, Paradies G. Melatonin inhibits cardiolipin peroxidation in mitochondria and prevents the mitochondrial permeability transition and cytochrome c release. Free Radic Biol Med 2009; 47: 969-74.
-
(2009)
Free Radic Biol Med
, vol.47
, pp. 969-974
-
-
Petrosillo, G.1
Moro, N.2
Ruggiero, F.M.3
Paradies, G.4
-
101
-
-
70349624362
-
Melatonin protects against heart ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening
-
Petrosillo G, Colantuono G, Moro N, et al. Melatonin protects against heart ischemia-reperfusion injury by inhibiting mitochondrial permeability transition pore opening. Am J Physiol Heart Circ Physiol 2009; 297: H1487-93.
-
(2009)
Am J Physiol Heart Circ Physiol
, vol.297
-
-
Petrosillo, G.1
Colantuono, G.2
Moro, N.3
|