1,2,3-Triazole tethered β-lactam-Chalcone bifunctional hybrids: Synthesis and anticancer evaluation

European Journal of Medicinal Chemistry

Volumn 47, Issue 1, 2012, Pages 594-600

  Singh, Pardeep ^a   Raj, Raghu ^a   Kumar, Vipan ^a   Mahajan, Mohinder P ^a,c   Bedi, P M S ^a   Kaur, Tandeep ^b   Saxena, A K ^b  

^a GURU NANAK DEV UNIVERSITY   (India)

^b CSIR INDIAN INSTITUTE OF INTEGRATIVE MEDICINE   (India)

^c Apeejay Stya Research Foundation   (India)

Author keywords

Lactam; Anticancer evaluation; Bifunctional hybrids; Chalcone; Triazole

Indexed keywords

1 CYCLOHEXYL 3 [4 [2 METHOXY 4 [3 (4 METHOXYPHENYL)PHENYL] 3 OXO PROPENYL]PHENOXYMETHYL] [1,2,3]TRIAZOL 1 YL) 4 STYRYL AZETIDIN 2 ONE; 1 CYCLOHEXYL 3 [4 [4 [3 (2 METHOXY PHENYL)ACRYLOYL]PHENOXYMETHYL] [1,2,3] TRIAZOL 1 YL] 4 STYRYL AZETIDIN 2 ONE; 1 CYCLOHEXYL 3 [4 [4 [3 (2,4 DIMETHOXY PHENYL) 3 OXO PROPENYL] 2 METHOXY PHENOXYMETHYL] [1,2,3]TRIAZOL 1 YL] 4 STYRYL AZETIDIN 2 ONE; 1 CYCLOHEXYL 3 [4 [4 [3 (4 METHOXY PHENYL)ACRYLOYL]PHENOXYMETHYL] [1,2,3] TRIAZOL 1 YL] 4 STYRYL AZETIDIN 2 ONE; 1,2,3 TRIAZOLE DERIVATIVE; 3 [4 [2 METHOXY 4 (3 OXO 3 PHENYL PROPENYL) PHENOXYMETHYL] [1,2,3] TRIAZOL 1 YL] 4 STYRYL 1 P TOLYL AZETIDIN 2 ONE; 3 [4 [2 METHOXY 4 [3 (4 METHOXY PHENYL) 3 OXO PROPENYL]PHENOXYMETHYL] [1,2,3] TRIAZOL 1 YL] 4 STYRYL 1 P TOLYL AZETIDIN 2 ONE; 3 [4 [4 [3 (2 METHOXY PHENYL)ACRYLOYL]PHENOXYMETHYL] [1,2,3] TRIAZOL 1 YL) 4 STYRYL 1 P TOLYL AZETIDIN 2 ONE; 3 [4 [4 [3 (2,4 DIMETHOXY PHENYL) 3 OXO PROPENYL] 2 METHOXY PHENOXYMETHYL] [1,2,3]TRIAZOL 1 YL] 4 STYRYL 1 P PTOLYL AZETIDIN 2 ONE; 3 [4 [4 [3 (4 METHOXY PHENYL)ACRYLOYL]PHENOXYMETHYL] [1,2,3] TRIAZOL 1 YL) 4 STYRYL 1 P TOLYL AZETIDIN 2 ONE; 3 METHOXY 4 [1 (2 OXO 4 STYRYL 1 P TOLYL AZETIDIN 3 YL) 1H [1,2,3] TRIAZOL 4 YLMETHOXY]BENZALDEHYDE; 4 [1 (1 CYCLOHEXYL 2 OXO 4 STYRYL AZETIDIN 3 YL) 1H [1,2,3] TRIAZOL 4 YLMETHOXY] 3 METHOXY BENZALDEHYDE; ALKYNE DERIVATIVE; ANTINEOPLASTIC AGENT; AZIDE; BETA LACTAM DERIVATIVE; CHALCONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; ARTICLE; CANCER CELL; COLON CANCER; CYCLOADDITION; DRUG SYNTHESIS; HUMAN; HUMAN CELL; LEUKEMIA; LUNG CANCER; PROSTATE CANCER;

ANTINEOPLASTIC AGENTS; BETA-LACTAMS; CELL LINE, TUMOR; CELL PROLIFERATION; CHALCONE; HUMANS; INHIBITORY CONCENTRATION 50; TRIAZOLES;

EID: 84855800613     PISSN: 02235234     EISSN: 17683254     Source Type: Journal    
DOI: 10.1016/j.ejmech.2011.10.033     Document Type: Article

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