Synthesis, antimalarial and antitubercular activity of acetylenic chalcones

Bioorganic and Medicinal Chemistry Letters

Volumn 20, Issue 3, 2010, Pages 942-944

  Hans, Renate H ^a   Guantai, Eric M ^a   Lategan, Carmen ^a   Smith, Peter J ^a   Wan, Baojie ^b   Franzblau, Scott G ^b   Gut, Jiri ^c   Rosenthal, Philip J ^c   Chibale, Kelly ^a  

^a UNIVERSITY OF CAPE TOWN   (South Africa)

^b UNIVERSITY OF ILLINOIS AT CHICAGO   (United States)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Chalcones; Falcipain 2; M. tuberculosis; P. falciparum

Indexed keywords

6,7 DIHYDRO 2 NITRO 6 (4 TRIFLUOROMETHOXYBENZYLOXY) 5H IMIDAZO[2,1 B][1,3]OXAZINE; ACETYLENE DERIVATIVE; ANTIMALARIAL AGENT; CHALCONE DERIVATIVE; CHLOROQUINE; ISONIAZID; MOXIFLOXACIN; RIFAMPICIN; TUBERCULOSTATIC AGENT; ALKYNE;

ANTIBACTERIAL ACTIVITY; ANTIMALARIAL ACTIVITY; ARTICLE; BACTERIUM CULTURE; CONTROLLED STUDY; DRUG SYNTHESIS; GROWTH INHIBITION; MICROBIAL GROWTH; MYCOBACTERIUM TUBERCULOSIS; NONHUMAN; PLASMODIUM FALCIPARUM; COMPARATIVE STUDY; DRUG EFFECTS; PHYSIOLOGY; SYNTHESIS;

MYCOBACTERIUM TUBERCULOSIS; PLASMODIUM FALCIPARUM;

ALKYNES; ANTIMALARIALS; ANTITUBERCULAR AGENTS; CHALCONES; MYCOBACTERIUM TUBERCULOSIS; PLASMODIUM FALCIPARUM;

EID: 74049149436     PISSN: 0960894X     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmcl.2009.12.062     Document Type: Article

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