Amyloid β interacts with the amyloid precursor protein: A potential toxic mechanism in Alzheimer's disease

Nature Neuroscience

Volumn 3, Issue 5, 2000, Pages 460-464

  Lorenzo, Alfredo ^a,b   Yuan, Menglan ^a   Zhang, Zhuohua ^a   Paganetti, Paolo A ^c   Sturchler Pierrat, Christine ^c   Staufenbiel, Matthias ^c   Mautino, Jorge ^b   Sol Vigo, Francisco ^b   Sommer, Bernd ^c   Yankner, Bruce A ^a  

^a BOSTON CHILDREN S HOSPITAL   (United States)

^b INSTITUTO DE INVESTIGACIÓN MÉDICA MERCEDES Y MARTÍN FERREYRA   (Argentina)

^c NOVARTIS PHARMA AG   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

AMYLOID; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; MEMBRANE PROTEIN;

ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; AUTOSOMAL DOMINANT DISORDER; BRAIN CELL; CELL SURFACE; NERVE CELL DEGENERATION; NEUROTOXICITY; NONHUMAN; PRION; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN PROTEIN INTERACTION; RAT;

ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BIOPOLYMERS; CELL MEMBRANE; CELLS, CULTURED; CEREBRAL CORTEX; GENE DELETION; HIPPOCAMPUS; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; NEURONS; PROTEIN BINDING; RATS; SENILE PLAQUES; SOLUBILITY;

EID: 0033944538     PISSN: 10976256     EISSN: None     Source Type: Journal    
DOI: 10.1038/74833     Document Type: Article

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