IL-1β induces MMP-9 expression via a Ca2+-dependent CaMKII/JNK/c-Jun cascade in rat brain astrocytes

GLIA

Volumn 57, Issue 16, 2009, Pages 1775-1789

  Wu, Cheng Ying ^a   Hsieh, Hsi Lung ^b   Sun, Chi Chin ^c   Yang, Chuen Mao ^a  

^a CHANG GUNG UNIVERSITY   (Taiwan)

^b CHANG GUNG UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Taiwan)

^c CHANG GUNG MEMORIAL HOSPITAL   (Taiwan)

Author keywords

Brain inflammation; Chromatin remodeling; Cytokines; MAPKs; Matrix metalloproteinases

Indexed keywords

1 [N,O BIS(5 ISOQUINOLINESULFONYL) N METHYLTYROSYL] 4 PHENYLPIPERAZINE; ANTHRA[1,9 CD]PYRAZOL 6(2H) ONE; CALCIUM CALMODULIN DEPENDENT PROTEIN KINASE II; CALCIUM ION; ETHYLENE GLYCOL 1,2 BIS(2 AMINOPHENYL) ETHER N,N,N',N' TETRAACETIC ACID; GELATINASE B; INTERLEUKIN 1BETA; LUCIFERASE; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE P38; SHORT HAIRPIN RNA; STRESS ACTIVATED PROTEIN KINASE; STRESS ACTIVATED PROTEIN KINASE 1; THAPSIGARGIN; TRANSCRIPTION FACTOR AP 1; CALCIUM; ENZYME INHIBITOR; PROTEIN C JUN;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; ASTROCYTE; BINDING AFFINITY; BINDING SITE; CALCIUM CELL LEVEL; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME INDUCTION; ENZYME PHOSPHORYLATION; GENE EXPRESSION REGULATION; NONHUMAN; NUCLEOTIDE SEQUENCE; PLASMID; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; PROTEIN FUNCTION; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; TRANSCRIPTION INITIATION; TRANSIENT TRANSFECTION; UPREGULATION; WESTERN BLOTTING; ZYMOGRAPHY; ANALYSIS OF VARIANCE; ANIMAL; BRAIN; CELL LINE; DRUG EFFECT; GEL MOBILITY SHIFT ASSAY; GENETIC TRANSFECTION; GENETICS; METABOLISM; PHOSPHORYLATION; PHYSIOLOGY; TWO DIMENSIONAL GEL ELECTROPHORESIS;

ANALYSIS OF VARIANCE; ANIMALS; ASTROCYTES; BLOTTING, WESTERN; BRAIN; CALCIUM; CALCIUM-CALMODULIN-DEPENDENT PROTEIN KINASE TYPE 2; CELL LINE; CHROMATIN IMMUNOPRECIPITATION; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; ELECTROPHORETIC MOBILITY SHIFT ASSAY; ENZYME INHIBITORS; INTERLEUKIN-1BETA; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MATRIX METALLOPROTEINASE 9; PHOSPHORYLATION; PROMOTER REGIONS, GENETIC; PROTO-ONCOGENE PROTEINS C-JUN; RATS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; SIGNAL TRANSDUCTION; TRANSFECTION; UP-REGULATION;

EID: 71249161927     PISSN: 08941491     EISSN: 10981136     Source Type: Journal    
DOI: 10.1002/glia.20890     Document Type: Article

References (34)

1. Allan SM, Tyrrell PJ, Rothwell NJ. 2005. Interleukin-1 and neuronal injury. Nat Rev Immunol 5:629-640.
2. Bayer KU, Schulman H. 2001. Regulation of signal transduction by protein targeting: The case for CaMKII. Biochem Biophys Res Commun 289:917-923. (Pubitemid 34076276)
3. Berridge MJ, Bootman MD, Roderick HL. 2003. Calcium signalling: Dynamics, homeostasis and remodelling. Nat Rev Mol Cell Biol 4:517-529.
4. 2+ entry. Am J Physiol Cell Physiol 293:C1103-C1111.
5. Deckert-Schluter M, Schluter D, Schwendemann G. 1992. Evaluation of IL-2, sIL2R, IL-6, TNF-α, and IL-1β levels in serum and CSF of patients with optic neuritis. J Neurol Sci 113:50-54.
6. Eberhardt W, Schulze M, Engels C, Klasmeier E, Pfeilschifter J. 2002. Glucocorticoid-mediated suppression of cytokine-induced matrix metalloproteinase- 9 expression in rat mesangial cells: Involvement of nuclear factor-κB and Ets transcription factors. Mol Endocrinol 16:1752-1766. (Pubitemid 34828086)
7. Fassbender K, Rossol S, Kammer T, Daffertshofer M, Wirth S, Dollman M, Hennerici M. 1994. Proinflammatory cytokines in serum of patients with acute cerebral ischemia: Kinetics of secretion and relation to the extent of brain damage and outcome of disease. J Neurol Sci 122:135-139. (Pubitemid 24097260)
8. 2+/calmodulin-dependent protein kinase II]. Yakugaku Zasshi 126:337-342.
9. Gao Y, Signore AP, Yin W, Cao G, Yin XM, Sun F, Luo Y, Graham SH, Chen J. 2005. Neuroprotection against focal ischemic brain injury by inhibition of c-Jun N-terminal kinase and attenuation of the mitochondrial apoptosis-signaling pathway. J Cereb Blood Flow Metab 25:694-712. (Pubitemid 40705605)
10. Gee K, Angel JB, Mishra S, Blahoianu MA, Kumar A. 2007. IL-10 regulation by HIV-Tat in primary human monocytic cells: Involvement of calmodulin/ calmodulin-dependent protein kinase-activated p38 MAPK and Sp-1 and CREB-1 transcription factors. J Immunol 178:798-807. (Pubitemid 46095152)
11. Gottschall PE, Yu X, Bing B. 1995. Increased production of gelatinase B (matrix metalloproteinase-9) and interleukin-6 by activated rat microglia in culture. J Neurosci Res 42:335-342.
12. 2+ indicators with greatly improved fluorescence properties. J Biol Chem 260:3440-3450.
13. Han S, Ritzenthaler JD, Sitaraman SV, Roman J. 2006. Fibronectin increases matrix metalloproteinase 9 expression through activation of c-Fos via extracellular-regulated kinase and phosphatidylinositol 3-kinase pathways in human lung carcinoma cells. J Biol Chem 281:29614-29624. (Pubitemid 44536969)
14. Holliday J, Gruol DL. 1993. Cytokine stimulation increases intracellular calcium and alters the response to quisqualate in cultured cortical astrocytes. Brain Res 621:233-241. (Pubitemid 23248082)
15. Jou TC, Jou MJ, Chen JY, Lee SY. 1985. [Properties of rat brain astrocytes in long-term culture]. Taiwan Yi Xue Hui Za Zhi 84:865-881.
16. Korzus E, Nagase H, Rydell R, Travis J. 1997. The mitogen-activated protein kinase and JAK-STAT signaling pathways are required for an oncostatin M-responsive element-mediated activation of matrix metalloproteinase 1 gene expression. J Biol Chem 272:1188-1196. (Pubitemid 27034616)
17. Leppa S, Saffrich R, Ansorge W, Bohmann D. 1998. Differential regulation of c-Jun by ERK, JNK during PC12 cell differentiation. EMBO J 17:4404-4413. (Pubitemid 28362630)
18. Leppert D, Lindberg RLP, Kappos L, Leib SL. 2001. Matrix metalloproteinases: Multifunctional effectors of inflammation in multiple sclerosis and bacterial meningitis. Brain Res Rev 36:249-257. (Pubitemid 33020755)
19. McGuinness OP, Shau V, Benson EM, Lewis M, Snowden RT, Greene JE, Neal DW, Cherrington AD. 1997. Role of epinephrine and norepinephrine in the metabolic response to stress hormone infusion in the conscious dog. Am J Physiol 273:E674-E681.
20. Mogi M, Harada M, Kondo T, Riederer P, Inagaki H, Minami M, Nagatsu T. 1994. Interleukin-1β, interleukin-6, epidermal growth factor and transforming growth factor-α are elevated in the brain from parkinsonian patients. Neurosci Lett 180:147-150.
21. Nair VD, Sealfon SC. 2003. Agonist-specific transactivation of phosphoinositide 3-kinase signaling pathway mediated by the dopamine D2 receptor. J Biol Chem 278:47053-47061.
22. Pita I, Jelaso AM, Ide CF. 1999. IL-1β increases intracellular calcium through an IL-1 type 1 receptor mediated mechanism in C6 astrocytic cells. Int J Dev Neurosci 17:813-820.
23. 2+/calmodulin- dependent protein kinase II in osteoblastic cells. J Mol Endocrinol 25:73-84.
24. Rangaswami H, Bulbule A, Kundu GC. 2005. JNK1 differentially regulates osteopontin-induced nuclear factor-inducing kinase/MEKK1- dependent activating protein-1-mediated promatrix metalloproteinase- 9 activation. J Biol Chem 280:19381-19392.
25. Rosenberg GA. 2002a. Matrix metalloproteinases and neuroinflammation in multiple sclerosis. Neuroscientist 8:586-595.
26. Rosenberg GA. 2002b. Matrix metalloproteinases in neuroinflammation. Glia 39:279-291.
27. Rosengart MR, Arbabi S, Garcia I, Maier RV. 2000. Interactions of calcium/calmodulin-dependent protein kinases (CaMK) and extracellular- regulated kinase (ERK) in monocyte adherence and TNFα production. Shock 13:183-189.
28. Rothwell N. 2003. Interleukin-1 and neuronal injury: Mechanisms, modification, and therapeutic potential. Brain Behav Immun 17:152-157. (Pubitemid 36434364)
29. Shaulian E, Karin M. 2001. AP-1 in cell proliferation and survival. Oncogene 20:2390-2400.
30. Svedin P, Hagberg H, Savman K, Zhu C, Mallard C. 2007. Matrix metalloproteinase- 9 gene knock-out protects the immature brain after cerebral hypoxia-ischemia. J Neurosci 27:1511-1518. (Pubitemid 46280068)
31. Wang Q, Downey GP, Bajenova E, Abreu M, Kapus A, McCulloch CA. 2005. Mitochondrial function is a critical determinant of IL-1-induced ERK activation. FASEB J 19:837-839. (Pubitemid 40617401)
32. Wang W, Hou XY, Gao C, Liu Y, Zong YY, Zhang GY. 2003. Regulation of c-Jun N-terminal kinase activation in hydrogen peroxide induced neurotoxicity. J Neurocytol 32:143-151. (Pubitemid 38019306)
33. Woo CH, Lim JH, Kim JH. 2004. Lipopolysaccharide induces matrix metalloproteinase-9 expression via a mitochondrial reactive oxygen species-p38 kinase-activator protein-1 pathway in Raw 264.7 cells. J Immunol 173:6973-6980.
34. Wu CY, Hsieh HL, Jou MJ, Yang CM. 2004. Involvement of p42/p44 MAPK, p38 MAPK, JNK and nuclear factor-κ B in interleukin-1β-induced matrix metalloproteinase-9 expression in rat brain astrocytes J Neurochem 90:1477-1488.