-
1
-
-
0032877668
-
Dysregulation of apoptosis in cancer
-
J.C. Reed Dysregulation of apoptosis in cancer J. Clin. Oncol. 17 1999 2941 2953
-
(1999)
J. Clin. Oncol.
, vol.17
, pp. 2941-2953
-
-
Reed, J.C.1
-
2
-
-
0035823503
-
Defective Cytochrome c-dependent caspase activation in ovarian cancer cell lines due to diminished or absent apoptotic protease activating factor-1 activity
-
B.B. Wolf, M. Schuler, W. Li, B. Eggers-Sedlet, W. Lee, P. Tailor, P. Fitzgerald, G.B. Mills, and D.R. Green Defective Cytochrome c-dependent caspase activation in ovarian cancer cell lines due to diminished or absent apoptotic protease activating factor-1 activity J. Biol. Chem. 276 2001 34244 34251
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 34244-34251
-
-
Wolf, B.B.1
Schuler, M.2
Li, W.3
Eggers-Sedlet, B.4
Lee, W.5
Tailor, P.6
Fitzgerald, P.7
Mills, G.B.8
Green, D.R.9
-
3
-
-
0035266318
-
XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cells
-
E. Asselin, G.B. Mills, and B.K. Tsang XIAP regulates Akt activity and caspase-3-dependent cleavage during cisplatin-induced apoptosis in human ovarian epithelial cancer cells Cancer Res. 61 2001 1862 1868
-
(2001)
Cancer Res.
, vol.61
, pp. 1862-1868
-
-
Asselin, E.1
Mills, G.B.2
Tsang, B.K.3
-
4
-
-
0036468550
-
Dysfunctional apoptosome activation in ovarian cancer: Implications for chemoresistance
-
J.R. Liu, A.W. Opipari, L. Tan, Y. Jiang, Y. Zhang, H. Tang, and G. Nunez Dysfunctional apoptosome activation in ovarian cancer: implications for chemoresistance Cancer Res. 62 2002 924 931
-
(2002)
Cancer Res.
, vol.62
, pp. 924-931
-
-
Liu, J.R.1
Opipari, A.W.2
Tan, L.3
Jiang, Y.4
Zhang, Y.5
Tang, H.6
Nunez, G.7
-
5
-
-
0036693488
-
Expression of the anti-apoptotic gene survivin correlates with Taxol resistance in human ovarian cancer
-
N. Zaffaroni, M. Pennati, G. Colella, P. Perego, R. Supino, L. Gatti, S. Pilotti, F. Zunino, and M.G. Daidone Expression of the anti-apoptotic gene survivin correlates with Taxol resistance in human ovarian cancer Cell. Mol. Life Sci. 59 2002 1406 1412
-
(2002)
Cell. Mol. Life Sci.
, vol.59
, pp. 1406-1412
-
-
Zaffaroni, N.1
Pennati, M.2
Colella, G.3
Perego, P.4
Supino, R.5
Gatti, L.6
Pilotti, S.7
Zunino, F.8
Daidone, M.G.9
-
6
-
-
0028880293
-
The control of apoptosis and drug resistance in ovarian cancer: Influence of p53 and Bcl-2
-
A. Eliopoulos, D. Kerr, J. Herod, E. Hodgkins, S. Krajewski, J. Reed, and L. Young The control of apoptosis and drug resistance in ovarian cancer: influence of p53 and Bcl-2 Oncogene 11 1995 1217 1228
-
(1995)
Oncogene
, vol.11
, pp. 1217-1228
-
-
Eliopoulos, A.1
Kerr, D.2
Herod, J.3
Hodgkins, E.4
Krajewski, S.5
Reed, J.6
Young, L.7
-
7
-
-
0035831019
-
Structural basis for the inhibition of caspase-3 by XIAP
-
S.J. Riedl, M. Renatus, R. Schwarzenbacher, Q. Zhou, C. Sun, S.W. Fesik, R.C. Liddington, and G.S. Salvesen Structural basis for the inhibition of caspase-3 by XIAP Cell 104 2001 791 800
-
(2001)
Cell
, vol.104
, pp. 791-800
-
-
Riedl, S.J.1
Renatus, M.2
Schwarzenbacher, R.3
Zhou, Q.4
Sun, C.5
Fesik, S.W.6
Liddington, R.C.7
Salvesen, G.S.8
-
8
-
-
0037291737
-
Mechanism of XIAP-mediated inhibition of caspase-9
-
E.N. Shiozaki, J. Chai, D.J. Rigotti, S.J. Riedl, P.W. Li, S.M. Srinivasula, E.S. Alnemri, R. Fairman, and Y. Shi Mechanism of XIAP-mediated inhibition of caspase-9 Mol. Cell 11 2003 519 527
-
(2003)
Mol. Cell
, vol.11
, pp. 519-527
-
-
Shiozaki, E.N.1
Chai, J.2
Rigotti, D.J.3
Riedl, S.J.4
Li, P.W.5
Srinivasula, S.M.6
Alnemri, E.S.7
Fairman, R.8
Shi, Y.9
-
9
-
-
0034607655
-
Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli
-
Y. Yang, S. Fang, J.P. Jensen, A.M. Weissman, and J.D. Ashwell Ubiquitin protein ligase activity of IAPs and their degradation in proteasomes in response to apoptotic stimuli Science 288 2000 874 877
-
(2000)
Science
, vol.288
, pp. 874-877
-
-
Yang, Y.1
Fang, S.2
Jensen, J.P.3
Weissman, A.M.4
Ashwell, J.D.5
-
10
-
-
0034616942
-
Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins
-
A. Verhagen, P. Ekert, M. Pakusch, J. Silke, L. Connolly, G. Reid, R. Moritz, R. Simpson, and D. Vaux Identification of DIABLO, a mammalian protein that promotes apoptosis by binding to and antagonizing IAP proteins Cell 102 2000 43 53
-
(2000)
Cell
, vol.102
, pp. 43-53
-
-
Verhagen, A.1
Ekert, P.2
Pakusch, M.3
Silke, J.4
Connolly, L.5
Reid, G.6
Moritz, R.7
Simpson, R.8
Vaux, D.9
-
11
-
-
0034616945
-
Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition
-
C. Du, M. Fang, Y. Li, L. Li, and X. Wang Smac, a mitochondrial protein that promotes cytochrome c-dependent caspase activation by eliminating IAP inhibition Cell 102 2000 33 42
-
(2000)
Cell
, vol.102
, pp. 33-42
-
-
Du, C.1
Fang, M.2
Li, Y.3
Li, L.4
Wang, X.5
-
12
-
-
0036141029
-
TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO
-
Y. Deng, Y. Lin, and X. Wu TRAIL-induced apoptosis requires Bax-dependent mitochondrial release of Smac/DIABLO Genes Dev. 16 2002 33 45
-
(2002)
Genes Dev.
, vol.16
, pp. 33-45
-
-
Deng, Y.1
Lin, Y.2
Wu, X.3
-
13
-
-
0035816553
-
Apaf-1/Cytochrome c-independent and Smac-dependent induction of apoptosis in Multiple Myeloma (MM) cells
-
D. Chauhan, T. Hideshima, S. Rosen, J.C. Reed, S. Kharbanda, and K.C. Anderson Apaf-1/Cytochrome c-independent and Smac-dependent induction of apoptosis in Multiple Myeloma (MM) cells J. Biol. Chem. 276 2001 24453 24456
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 24453-24456
-
-
Chauhan, D.1
Hideshima, T.2
Rosen, S.3
Reed, J.C.4
Kharbanda, S.5
Anderson, K.C.6
-
14
-
-
0036233590
-
Generation and characterization of Smac/DIABLO-deficient mice
-
H. Okada, W.-K. Suh, J. Jin, M. Woo, C. Du, A. Elia, G.S. Duncan, A. Wakeham, A. Itie, S.W. Lowe, X. Wang, and T.W. Mak Generation and characterization of Smac/DIABLO-deficient mice Mol. Cell. Biol. 22 2002 3509 3517
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 3509-3517
-
-
Okada, H.1
Suh, W.-K.2
Jin, J.3
Woo, M.4
Du, C.5
Elia, A.6
Duncan, G.S.7
Wakeham, A.8
Itie, A.9
Lowe, S.W.10
Wang, X.11
Mak, T.W.12
-
15
-
-
18544386724
-
Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction
-
R. Hegde, S.M. Srinivasula, Z. Zhang, R. Wassell, R. Mukattash, L. Cilenti, G. DuBois, Y. Lazebnik, A.S. Zervos, T. Fernandes-Alnemri, and E.S. Alnemri Identification of Omi/HtrA2 as a mitochondrial apoptotic serine protease that disrupts inhibitor of apoptosis protein-caspase interaction J. Biol. Chem. 277 2002 432 438
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 432-438
-
-
Hegde, R.1
Srinivasula, S.M.2
Zhang, Z.3
Wassell, R.4
Mukattash, R.5
Cilenti, L.6
Dubois, G.7
Lazebnik, Y.8
Zervos, A.S.9
Fernandes-Alnemri, T.10
Alnemri, E.S.11
-
16
-
-
0037016707
-
The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif
-
L.M. Martins, I. Iaccarino, T. Tenev, S. Gschmeissner, N.F. Totty, N.R. Lemoine, J. Savopoulos, C.W. Gray, C.L. Creasy, C. Dingwall, and J. Downward The serine protease Omi/HtrA2 regulates apoptosis by binding XIAP through a reaper-like motif J. Biol. Chem. 277 2002 439 444
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 439-444
-
-
Martins, L.M.1
Iaccarino, I.2
Tenev, T.3
Gschmeissner, S.4
Totty, N.F.5
Lemoine, N.R.6
Savopoulos, J.7
Gray, C.W.8
Creasy, C.L.9
Dingwall, C.10
Downward, J.11
-
17
-
-
0141643236
-
The polypeptide chain-releasing factor GSPT1/eRF3 is proteolytically processed into an IAP-binding protein
-
R. Hegde, S.M. Srinivasula, P. Datta, M. Madesh, R. Wassell, Z. Zhang, N. Cheong, J. Nejmeh, T. Fernandes-Alnemri, S.-I. Hoshino, and E.S. Alnemri The polypeptide chain-releasing factor GSPT1/eRF3 is proteolytically processed into an IAP-binding protein J. Biol. Chem. 278 2003 38699 38706
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 38699-38706
-
-
Hegde, R.1
Srinivasula, S.M.2
Datta, P.3
Madesh, M.4
Wassell, R.5
Zhang, Z.6
Cheong, N.7
Nejmeh, J.8
Fernandes-Alnemri, T.9
Hoshino, S.-I.10
Alnemri, E.S.11
-
18
-
-
0242440802
-
Substrate cleavage by caspases generates protein fragments with Smac/DIABLO-like activities
-
K. Hell, M. Saleh, G.D. Crescenzo, M.D. O'Connor-McCourt, and D.W. Nicholson Substrate cleavage by caspases generates protein fragments with Smac/DIABLO-like activities Cell Death Differ. 10 2003 1234 1239
-
(2003)
Cell Death Differ.
, vol.10
, pp. 1234-1239
-
-
Hell, K.1
Saleh, M.2
Crescenzo, G.D.3
O'Connor-Mccourt, M.D.4
Nicholson, D.W.5
-
19
-
-
0036565885
-
Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis
-
F. Guo, R. Nimmanapalli, S. Paranawithana, S. Wittman, D. Griffin, P. Bali, E. O'Bryan, C. Fumero, H.G. Wang, and K. Bhalla Ectopic overexpression of second mitochondria-derived activator of caspases (Smac/DIABLO) or cotreatment with N-terminus of Smac/DIABLO peptide potentiates epothilone B derivative-(BMS 247550) and Apo-2L/TRAIL-induced apoptosis Blood 99 2002 3419 3426
-
(2002)
Blood
, vol.99
, pp. 3419-3426
-
-
Guo, F.1
Nimmanapalli, R.2
Paranawithana, S.3
Wittman, S.4
Griffin, D.5
Bali, P.6
O'Bryan, E.7
Fumero, C.8
Wang, H.G.9
Bhalla, K.10
-
20
-
-
0036341291
-
Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo
-
S. Fulda, W. Wick, M. Weller, and K.M. Debatin Smac agonists sensitize for Apo2L/TRAIL- or anticancer drug-induced apoptosis and induce regression of malignant glioma in vivo Nat. Med. 8 2002 808 815
-
(2002)
Nat. Med.
, vol.8
, pp. 808-815
-
-
Fulda, S.1
Wick, W.2
Weller, M.3
Debatin, K.M.4
-
21
-
-
0347895102
-
Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAPI in situ
-
C.R. Arnt, M.V. Chiorean, M.P. Heldebrant, G.J. Gores, and S.H. Kaufmann Synthetic Smac/DIABLO peptides enhance the effects of chemotherapeutic agents by binding XIAP and cIAPI in situ J. Biol. Chem. 277 2002 44236 44243
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44236-44243
-
-
Arnt, C.R.1
Chiorean, M.V.2
Heldebrant, M.P.3
Gores, G.J.4
Kaufmann, S.H.5
-
22
-
-
8444251451
-
Unlike DIABLO/Smac, grim promotes global ubiquitination and specific degradation of XIAP and neither cause apoptosis
-
J.H. Silke, T. Kratina, P.G. Ekert, M. Pakusch, and D.L. Vaux Unlike DIABLO/Smac, grim promotes global ubiquitination and specific degradation of XIAP and neither cause apoptosis J. Biol. Chem. 279 2004
-
(2004)
J. Biol. Chem.
, vol.279
-
-
Silke, J.H.1
Kratina, T.2
Ekert, P.G.3
Pakusch, M.4
Vaux, D.L.5
-
23
-
-
0030746636
-
A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma
-
G. Ambrosini, C. Adida, and D. Altieri A novel anti-apoptosis gene, survivin, expressed in cancer and lymphoma Nat. Med. 3 1997 917 921
-
(1997)
Nat. Med.
, vol.3
, pp. 917-921
-
-
Ambrosini, G.1
Adida, C.2
Altieri, D.3
-
24
-
-
0035969963
-
An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and -7
-
S. Shin, B.J. Sung, Y.S. Cho, H.J. Kim, N.C. Ha, J.I. Hwang, C.W. Chung, Y.K. Jung, and B.H. Oh An anti-apoptotic protein human survivin is a direct inhibitor of caspase-3 and -7 Biochemistry 40 2001 1117 1123
-
(2001)
Biochemistry
, vol.40
, pp. 1117-1123
-
-
Shin, S.1
Sung, B.J.2
Cho, Y.S.3
Kim, H.J.4
Ha, N.C.5
Hwang, J.I.6
Chung, C.W.7
Jung, Y.K.8
Oh, B.H.9
-
26
-
-
0342657718
-
A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy
-
R.A. Olie, A.P. Simoes-Wust, B. Baumann, S.H. Leech, D. Fabbro, R.A. Stahel, and U. Zangemeister-Wittke A novel antisense oligonucleotide targeting survivin expression induces apoptosis and sensitizes lung cancer cells to chemotherapy Cancer Res. 60 2000 2805 2809
-
(2000)
Cancer Res.
, vol.60
, pp. 2805-2809
-
-
Olie, R.A.1
Simoes-Wust, A.P.2
Baumann, B.3
Leech, S.H.4
Fabbro, D.5
Stahel, R.A.6
Zangemeister-Wittke, U.7
-
27
-
-
10744221003
-
Ribozyme-mediated inhibition of survivin expression increases spontaneous and drug-induced apoptosis and decreases the tumorigenic potential of human prostate cancer cells
-
M. Pennati, M. Binda, G. Colella, M. Zoppe, M. Folini, S. Vignati, A. Valentini, L. Citti, M. De Cesare, G. Pratesi, M. Giacca, M.G. Daidone, and N. Zaffaroni Ribozyme-mediated inhibition of survivin expression increases spontaneous and drug-induced apoptosis and decreases the tumorigenic potential of human prostate cancer cells Oncogene 23 2004 386 394
-
(2004)
Oncogene
, vol.23
, pp. 386-394
-
-
Pennati, M.1
Binda, M.2
Colella, G.3
Zoppe, M.4
Folini, M.5
Vignati, S.6
Valentini, A.7
Citti, L.8
De Cesare, M.9
Pratesi, G.10
Giacca, M.11
Daidone, M.G.12
Zaffaroni, N.13
-
28
-
-
12244293398
-
Localization, dynamics and function of survivin revealed by expression of functional SurvivinDsRed fusion proteins in the living cell
-
A. Temme, M. Rieger, F. Reber, D. Lindemann, B. Weigle, P. Diestelkoetter-Bachert, G. Ehninger, M. Tatsuka, Y. Terada, and E.P. Rieber Localization, dynamics and function of survivin revealed by expression of functional SurvivinDsRed fusion proteins in the living cell Mol. Biol. Cell 14 2003 78 92
-
(2003)
Mol. Biol. Cell
, vol.14
, pp. 78-92
-
-
Temme, A.1
Rieger, M.2
Reber, F.3
Lindemann, D.4
Weigle, B.5
Diestelkoetter-Bachert, P.6
Ehninger, G.7
Tatsuka, M.8
Terada, Y.9
Rieber, E.P.10
-
30
-
-
0038376119
-
Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension
-
S.M.A. Lens, R.M.F. Wolthuis, R. Klompmaker, J. Kauw, R. Agami, T. Brummelkamp, G. Kops, and R.H. Medema Survivin is required for a sustained spindle checkpoint arrest in response to lack of tension EMBO J. 22 2003 2934 2947
-
(2003)
EMBO J.
, vol.22
, pp. 2934-2947
-
-
Lens, S.M.A.1
Wolthuis, R.M.F.2
Klompmaker, R.3
Kauw, J.4
Agami, R.5
Brummelkamp, T.6
Kops, G.7
Medema, R.H.8
-
31
-
-
0035810919
-
INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis
-
S.P. Wheatley, A. Carvalho, P. Vagnarelli, and W.C. Earnshaw INCENP is required for proper targeting of Survivin to the centromeres and the anaphase spindle during mitosis Curr. Biol. 11 2001 886 890
-
(2001)
Curr. Biol.
, vol.11
, pp. 886-890
-
-
Wheatley, S.P.1
Carvalho, A.2
Vagnarelli, P.3
Earnshaw, W.C.4
-
32
-
-
0036732808
-
Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and in a complex inase activity is phosphorylation
-
M.A. Bolton, W.J. Lan, S.E. Powers, M.L. McCleland, J. Kuang, and P.T. Stukenberg Aurora B kinase exists in a complex with survivin and INCENP and its kinase activity is stimulated by survivin binding and in a complex inase activity is phosphorylation Mol. Biol. Cell 13 2002 3064 3077
-
(2002)
Mol. Biol. Cell
, vol.13
, pp. 3064-3077
-
-
Bolton, M.A.1
Lan, W.J.2
Powers, S.E.3
McCleland, M.L.4
Kuang, J.5
Stukenberg, P.T.6
-
33
-
-
0037414775
-
Survivin enhances Aurora-B kinase activity and localizes Aurora-B in human cells
-
J. Chen, S. Jin, S.K. Tahir, H. Zhang, X. Liu, A.V. Sarthy, T.P. McGonigal, Z. Liu, S.H. Rosenberg, and S.-C. Ng Survivin enhances Aurora-B kinase activity and localizes Aurora-B in human cells J. Biol. Chem. 278 2003 486 490
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 486-490
-
-
Chen, J.1
Jin, S.2
Tahir, S.K.3
Zhang, H.4
Liu, X.5
Sarthy, A.V.6
McGonigal, T.P.7
Liu, Z.8
Rosenberg, S.H.9
Ng, S.-C.10
-
34
-
-
0038182537
-
HBXIP functions as a cofactor of survivin in apoptosis suppression
-
H. Marusawa, S.-I. Matsuzawa, K. Welsh, H. Zou, R. Armstrong, I. Tamm, and J.C. Reed HBXIP functions as a cofactor of survivin in apoptosis suppression EMBO J. 22 2003 2729 2740
-
(2003)
EMBO J.
, vol.22
, pp. 2729-2740
-
-
Marusawa, H.1
Matsuzawa, S.-I.2
Welsh, K.3
Zou, H.4
Armstrong, R.5
Tamm, I.6
Reed, J.C.7
-
35
-
-
0942290423
-
Rapid induction of mitochondrial events and caspase-independent apoptosis in Survivin-targeted melanoma cells
-
T. Liu, B. Brouha, and D. Grossman Rapid induction of mitochondrial events and caspase-independent apoptosis in Survivin-targeted melanoma cells Oncogene 23 2004 39 48
-
(2004)
Oncogene
, vol.23
, pp. 39-48
-
-
Liu, T.1
Brouha, B.2
Grossman, D.3
-
36
-
-
0345826036
-
Acute ablation of survivin uncovers p53-dependent mitotic checkpoint functions and control of mitochondrial apoptosis
-
E. Beltrami, J. Plescia, J.C. Wilkinson, C.S. Duckett, and D.C. Altieri Acute ablation of survivin uncovers p53-dependent mitotic checkpoint functions and control of mitochondrial apoptosis J. Biol. Chem. 279 2004 2077 2084
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 2077-2084
-
-
Beltrami, E.1
Plescia, J.2
Wilkinson, J.C.3
Duckett, C.S.4
Altieri, D.C.5
-
37
-
-
0038297558
-
Expression of Smac/DIABLO in ovarian carcinoma cells induces apoptosis via a caspase-9-mediated pathway
-
I.A. McNeish, S. Bell, T. McKay, T. Tenev, M. Marani, and N.R. Lemoine Expression of Smac/DIABLO in ovarian carcinoma cells induces apoptosis via a caspase-9-mediated pathway Exp. Cell Res. 286 2003 186 198
-
(2003)
Exp. Cell Res.
, vol.286
, pp. 186-198
-
-
McNeish, I.A.1
Bell, S.2
McKay, T.3
Tenev, T.4
Marani, M.5
Lemoine, N.R.6
-
38
-
-
0032828715
-
A generic protein purification method for protein complex characterization and proteome exploration
-
G. Rigaut, A. Shevchenko, B. Rutz, M. Wilm, M. Mann, and B. Seraphin A generic protein purification method for protein complex characterization and proteome exploration Nat. Biotechnol. 17 1999 1030 1032
-
(1999)
Nat. Biotechnol.
, vol.17
, pp. 1030-1032
-
-
Rigaut, G.1
Shevchenko, A.2
Rutz, B.3
Wilm, M.4
Mann, M.5
Seraphin, B.6
-
39
-
-
0034532701
-
The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner
-
J. Zhao, T. Tenev, L. Martins, J. Downward, and N. Lemoine The ubiquitin-proteasome pathway regulates survivin degradation in a cell cycle-dependent manner J. Cell Sci. 113 2000 4363 4371
-
(2000)
J. Cell Sci.
, vol.113
, pp. 4363-4371
-
-
Zhao, J.1
Tenev, T.2
Martins, L.3
Downward, J.4
Lemoine, N.5
-
40
-
-
0142188706
-
Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: Implication for cancer specific therapy
-
L. Yang, Z. Cao, H. Yan, and W.C. Wood Coexistence of high levels of apoptotic signaling and inhibitor of apoptosis proteins in human tumor cells: implication for cancer specific therapy Cancer Res. 63 2003 6815 6824
-
(2003)
Cancer Res.
, vol.63
, pp. 6815-6824
-
-
Yang, L.1
Cao, Z.2
Yan, H.3
Wood, W.C.4
-
41
-
-
0035163836
-
Caspase activation by adenovirus E4orf4 protein is cell line specific and is mediated by the death receptor pathway
-
A. Livne, R. Shtrichman, and T. Kleinberger Caspase activation by adenovirus E4orf4 protein is cell line specific and is mediated by the death receptor pathway J. Virol. 75 2001 789 798
-
(2001)
J. Virol.
, vol.75
, pp. 789-798
-
-
Livne, A.1
Shtrichman, R.2
Kleinberger, T.3
-
42
-
-
0035795418
-
The inhibitor of apoptosis protein-binding domain of Smac is not essential for its proapoptotic activity
-
D.L. Roberts, W. Merrison, M. MacFarlane, and G.M. Cohen The inhibitor of apoptosis protein-binding domain of Smac is not essential for its proapoptotic activity J. Cell Biol. 153 2001 221 228
-
(2001)
J. Cell Biol.
, vol.153
, pp. 221-228
-
-
Roberts, D.L.1
Merrison, W.2
MacFarlane, M.3
Cohen, G.M.4
-
43
-
-
0034700495
-
Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain
-
Z.H. Liu, C.H. Sun, E.T. Olejniczak, R.P. Meadows, S.F. Betz, T. Oost, J. Herrmann, J.C. Wu, and S.W. Fesik Structural basis for binding of Smac/DIABLO to the XIAP BIR3 domain Nature 408 2000 1004 1008
-
(2000)
Nature
, vol.408
, pp. 1004-1008
-
-
Liu, Z.H.1
Sun, C.H.2
Olejniczak, E.T.3
Meadows, R.P.4
Betz, S.F.5
Oost, T.6
Herrmann, J.7
Wu, J.C.8
Fesik, S.W.9
-
44
-
-
0035282570
-
A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis
-
S.M. Srinivasula, R. Hegde, A. Saleh, P. Datta, E. Shiozaki, J. Chai, R.A. Lee, P.D. Robbins, T. Fernandes-Alnemri, Y. Shi, and E.S. Alnemri A conserved XIAP-interaction motif in caspase-9 and Smac/DIABLO regulates caspase activity and apoptosis Nature 410 2001 112 116
-
(2001)
Nature
, vol.410
, pp. 112-116
-
-
Srinivasula, S.M.1
Hegde, R.2
Saleh, A.3
Datta, P.4
Shiozaki, E.5
Chai, J.6
Lee, R.A.7
Robbins, P.D.8
Fernandes-Alnemri, T.9
Shi, Y.10
Alnemri, E.S.11
-
45
-
-
0036187036
-
Three-dimensional structure of the apoptosome: Implications for assembly, procaspase-9 binding, and activation
-
D. Acehan, X.J. Jiang, D.G. Morgan, J.E. Heuser, X.D. Wang, and C.W. Akey Three-dimensional structure of the apoptosome: implications for assembly, procaspase-9 binding, and activation Mol. Cell 9 2002 423 432
-
(2002)
Mol. Cell
, vol.9
, pp. 423-432
-
-
Acehan, D.1
Jiang, X.J.2
Morgan, D.G.3
Heuser, J.E.4
Wang, X.D.5
Akey, C.W.6
-
46
-
-
0035807966
-
Dimer formation drives the activation of the cell death protease caspase 9
-
M. Renatus, H.R. Stennicke, F.L. Scott, R.C. Liddington, and G.S. Salvesen Dimer formation drives the activation of the cell death protease caspase 9 Proc. Natl. Acad. Sci. U. S. A. 98 2001 14250 14255
-
(2001)
Proc. Natl. Acad. Sci. U. S. A.
, vol.98
, pp. 14250-14255
-
-
Renatus, M.1
Stennicke, H.R.2
Scott, F.L.3
Liddington, R.C.4
Salvesen, G.S.5
-
47
-
-
0035809172
-
DIABLO promotes apoptosis by removing MIHA/XIAP from processed caspase 9
-
P. Ekert, J. Silke, C. Hawkins, A. Verhagen, and D. Vaux DIABLO promotes apoptosis by removing MIHA/XIAP from processed caspase 9 J. Cell Biol. 152 2001 483 490
-
(2001)
J. Cell Biol.
, vol.152
, pp. 483-490
-
-
Ekert, P.1
Silke, J.2
Hawkins, C.3
Verhagen, A.4
Vaux, D.5
-
48
-
-
0037023712
-
SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP)
-
D. Vucic, K. Deshayes, H. Ackerly, M.T. Pisabarro, S. Kadkhodayan, W.J. Fairbrother, and V.M. Dixit SMAC negatively regulates the anti-apoptotic activity of melanoma inhibitor of apoptosis (ML-IAP) J. Biol. Chem. 277 2002 12275 12279
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 12275-12279
-
-
Vucic, D.1
Deshayes, K.2
Ackerly, H.3
Pisabarro, M.T.4
Kadkhodayan, S.5
Fairbrother, W.J.6
Dixit, V.M.7
-
49
-
-
0033923368
-
Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement
-
M. Verdecia, H.-K. Huang, E. Dutil, D. Kaiser, T. Hunter, and J. Noel Structure of the human anti-apoptotic protein survivin reveals a dimeric arrangement Nat. Struct. Biol. 7 2000 602 608
-
(2000)
Nat. Struct. Biol.
, vol.7
, pp. 602-608
-
-
Verdecia, M.1
Huang, H.-K.2
Dutil, E.3
Kaiser, D.4
Hunter, T.5
Noel, J.6
-
50
-
-
0037137188
-
A highly conserved arginine is critical for the functional folding of inhibitor of apoptosis (IAP) BIR domains
-
L.E. Luque, K.P. Grape, and M. Junker A highly conserved arginine is critical for the functional folding of inhibitor of apoptosis (IAP) BIR domains Biochemistry 41 2002 13663 13671
-
(2002)
Biochemistry
, vol.41
, pp. 13663-13671
-
-
Luque, L.E.1
Grape, K.P.2
Junker, M.3
-
51
-
-
0037663452
-
Direct interaction between Survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during Taxol-induced apoptosis
-
Z. Song, X. Yao, and M. Wu Direct interaction between Survivin and Smac/DIABLO is essential for the anti-apoptotic activity of survivin during Taxol-induced apoptosis J. Biol. Chem. 278 2003 23130 23140
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 23130-23140
-
-
Song, Z.1
Yao, X.2
Wu, M.3
-
52
-
-
0033635269
-
Crystal structure and mutagenic analysis of the inhibitor-of-apoptosis protein survivin
-
S.W. Muchmore, J. Chen, C. Jakob, D. Zakula, E.D. Matayoshi, W. Wu, H.C. Zhang, F.Z. Li, S.C. Ng, and D.C. Altieri Crystal structure and mutagenic analysis of the inhibitor-of-apoptosis protein survivin Mol. Cell 6 2000 173 182
-
(2000)
Mol. Cell
, vol.6
, pp. 173-182
-
-
Muchmore, S.W.1
Chen, J.2
Jakob, C.3
Zakula, D.4
Matayoshi, E.D.5
Wu, W.6
Zhang, H.C.7
Li, F.Z.8
Ng, S.C.9
Altieri, D.C.10
-
53
-
-
0033635270
-
Crystal structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helical extensions
-
L. Chantalat, D.A. Skoufias, J.P. Kleman, B. Jung, O. Dideberg, and R.L. Margolis Crystal structure of human survivin reveals a bow tie-shaped dimer with two unusual alpha-helical extensions Mol. Cell 6 2000 183 189
-
(2000)
Mol. Cell
, vol.6
, pp. 183-189
-
-
Chantalat, L.1
Skoufias, D.A.2
Kleman, J.P.3
Jung, B.4
Dideberg, O.5
Margolis, R.L.6
-
54
-
-
0033436285
-
Transcriptional analysis of human survivin gene expression
-
F.Z. Li, and D.C. Altieri Transcriptional analysis of human survivin gene expression Biochem. J. 344 1999 305 311
-
(1999)
Biochem. J.
, vol.344
, pp. 305-311
-
-
Li, F.Z.1
Altieri, D.C.2
-
55
-
-
67651002555
-
COX-2-dependent stabilization of survivin in non-small cell lung cancer
-
K. Krysan, F.H. Merchant, L. Zhu, M. Dohadwala, J. Luo, Y. Lin, N. Heuze-Vourc'h, M. Pold, D. Seligson, D. Chia, L. Goodglick, H. Wang, R. Strieter, S. Sharma, and S. Dubinett COX-2-dependent stabilization of survivin in non-small cell lung cancer FASEB J. 2003 03-0369fje
-
(2003)
FASEB J.
-
-
Krysan, K.1
Merchant, F.H.2
Zhu, L.3
Dohadwala, M.4
Luo, J.5
Lin, Y.6
Heuze-Vourc'H, N.7
Pold, M.8
Seligson, D.9
Chia, D.10
Goodglick, L.11
Wang, H.12
Strieter, R.13
Sharma, S.14
Dubinett, S.15
-
56
-
-
0036124320
-
Expression of cyclooxygenase 2 is an independent prognostic factor in human ovarian carcinoma
-
C. Denkert, M. Kobel, S. Pest, I. Koch, S. Berger, M. Schwabe, A. Siegert, A. Reles, B. Klosterhalfen, and S. Hauptmann Expression of cyclooxygenase 2 is an independent prognostic factor in human ovarian carcinoma Am. J. Pathol. 160 2002 893 903
-
(2002)
Am. J. Pathol.
, vol.160
, pp. 893-903
-
-
Denkert, C.1
Kobel, M.2
Pest, S.3
Koch, I.4
Berger, S.5
Schwabe, M.6
Siegert, A.7
Reles, A.8
Klosterhalfen, B.9
Hauptmann, S.10
-
57
-
-
0036300082
-
Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms
-
S.J. Yoo, J.R. Huh, I. Muro, H. Yu, L. Wang, S.L. Wang, R.M. Feldman, R.J. Clem, H.A. Muller, and B.A. Hay Hid, Rpr and Grim negatively regulate DIAP1 levels through distinct mechanisms Nat. Cell Biol. 4 2002 416 424
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 416-424
-
-
Yoo, S.J.1
Huh, J.R.2
Muro, I.3
Yu, H.4
Wang, L.5
Wang, S.L.6
Feldman, R.M.7
Clem, R.J.8
Muller, H.A.9
Hay, B.A.10
-
58
-
-
0036303143
-
Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition
-
C.L. Holley, M.R. Olson, D.A. Colon-Ramos, and S. Kornbluth Reaper eliminates IAP proteins through stimulated IAP degradation and generalized translational inhibition Nat. Cell Biol. 4 2002 439 444
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 439-444
-
-
Holley, C.L.1
Olson, M.R.2
Colon-Ramos, D.A.3
Kornbluth, S.4
-
59
-
-
0036300083
-
Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1
-
H.D. Ryoo, A. Bergmann, H. Gonen, A. Ciechanover, and H. Steller Regulation of Drosophila IAP1 degradation and apoptosis by reaper and ubcD1 Nat. Cell Biol. 4 2002 432 438
-
(2002)
Nat. Cell Biol.
, vol.4
, pp. 432-438
-
-
Ryoo, H.D.1
Bergmann, A.2
Gonen, H.3
Ciechanover, A.4
Steller, H.5
-
60
-
-
0042170180
-
Survivin is required for stable checkpoint activation in Taxol-treated HeLa cells
-
A. Carvalho, M. Carmena, C. Sambade, W.C. Earnshaw, and S.P. Wheatley Survivin is required for stable checkpoint activation in Taxol-treated HeLa cells J. Cell Sci. 116 2003 2987 2998
-
(2003)
J. Cell Sci.
, vol.116
, pp. 2987-2998
-
-
Carvalho, A.1
Carmena, M.2
Sambade, C.3
Earnshaw, W.C.4
Wheatley, S.P.5
-
61
-
-
0034660014
-
Sensitisation of human carcinoma cells to the prodrug CB1954 by adenovirus vector-mediated expression of E. coli nitroreductase
-
S. Weedon, N. Green, I. McNeish, M. Gilligan, V. Mautner, C. Wrighton, A. Mountain, L. Young, D. Kerr, and P. Searle Sensitisation of human carcinoma cells to the prodrug CB1954 by adenovirus vector-mediated expression of E. coli nitroreductase Int. J. Cancer 86 2000 848 854
-
(2000)
Int. J. Cancer
, vol.86
, pp. 848-854
-
-
Weedon, S.1
Green, N.2
McNeish, I.3
Gilligan, M.4
Mautner, V.5
Wrighton, C.6
Mountain, A.7
Young, L.8
Kerr, D.9
Searle, P.10
-
62
-
-
0034284157
-
DNA replication of first-generation adenovirus vectors in tumor cells
-
D.S. Steinwaerder, C.A. Carlson, and A. Lieber DNA replication of first-generation adenovirus vectors in tumor cells Hum. Gene Ther. 11 2000 1933 1948
-
(2000)
Hum. Gene Ther.
, vol.11
, pp. 1933-1948
-
-
Steinwaerder, D.S.1
Carlson, C.A.2
Lieber, A.3
-
63
-
-
0021061819
-
Rapid colorimetric assay for cellular growth and survival: Application to proliferation and cytotoxicity assays
-
T. Mosmann Rapid colorimetric assay for cellular growth and survival: application to proliferation and cytotoxicity assays J. Immunol. Methods 65 1983 55 63
-
(1983)
J. Immunol. Methods
, vol.65
, pp. 55-63
-
-
Mosmann, T.1
-
64
-
-
0035017144
-
Herpes simplex virus thymidine kinase/ganciclovir-induced cell death is enhanced by co-expression of caspase-3 in ovarian carcinoma cells
-
I.A. McNeish, T. Tenev, S. Bell, M. Marani, G. Vassaux, and N. Lemoine Herpes simplex virus thymidine kinase/ganciclovir-induced cell death is enhanced by co-expression of caspase-3 in ovarian carcinoma cells Cancer Gene Ther. 8 2001 308 319
-
(2001)
Cancer Gene Ther.
, vol.8
, pp. 308-319
-
-
McNeish, I.A.1
Tenev, T.2
Bell, S.3
Marani, M.4
Vassaux, G.5
Lemoine, N.6
-
65
-
-
0037784054
-
Pro-caspase-3 expression in ovarian carcinoma cells increases survivin transcription which can be countered with a dominant negative mutant, survivin T34A; A combination gene therapy strategy
-
T.R. McKay, S. Bell, T. Tenev, V. Stoll, R. Lopes, N.R. Lemoine, and I.A. McNeish Pro-caspase-3 expression in ovarian carcinoma cells increases survivin transcription which can be countered with a dominant negative mutant, survivin T34A; a combination gene therapy strategy Oncogene 22 2003 3539 3547
-
(2003)
Oncogene
, vol.22
, pp. 3539-3547
-
-
McKay, T.R.1
Bell, S.2
Tenev, T.3
Stoll, V.4
Lopes, R.5
Lemoine, N.R.6
McNeish, I.A.7
-
66
-
-
0032478271
-
A simplified system for generating recombinant adenoviruses
-
T.-C. He, S. Zhou, L. Da Costa, J. Yu, K. Kinzler, and B. Vogelstein A simplified system for generating recombinant adenoviruses Proc. Natl. Acad. Sci. U. S. A. 95 1998 2509 2514
-
(1998)
Proc. Natl. Acad. Sci. U. S. A.
, vol.95
, pp. 2509-2514
-
-
He, T.-C.1
Zhou, S.2
Da Costa, L.3
Yu, J.4
Kinzler, K.5
Vogelstein, B.6
-
67
-
-
0034664030
-
Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90
-
P. Pandey, A. Saleh, A. Nakazawa, S. Kumar, S.M. Srinivasula, V. Kumar, R. Weichselbaum, C. Nalin, E.S. Alnemri, D. Kufe, and S. Kharbanda Negative regulation of cytochrome c-mediated oligomerization of Apaf-1 and activation of procaspase-9 by heat shock protein 90 EMBO J. 19 2000 4310 4322
-
(2000)
EMBO J.
, vol.19
, pp. 4310-4322
-
-
Pandey, P.1
Saleh, A.2
Nakazawa, A.3
Kumar, S.4
Srinivasula, S.M.5
Kumar, V.6
Weichselbaum, R.7
Nalin, C.8
Alnemri, E.S.9
Kufe, D.10
Kharbanda, S.11
-
68
-
-
0037855783
-
Cellular Inhibitor of Apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO
-
S. Hu, and X. Yang Cellular Inhibitor of Apoptosis 1 and 2 are ubiquitin ligases for the apoptosis inducer Smac/DIABLO J. Biol. Chem. 278 2003 10055 10060
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 10055-10060
-
-
Hu, S.1
Yang, X.2
-
69
-
-
0037184113
-
Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro
-
M. MacFarlane, W. Merrison, S.B. Bratton, and G.M. Cohen Proteasome-mediated degradation of Smac during apoptosis: XIAP promotes Smac ubiquitination in vitro J. Biol. Chem. 277 2002 36611 36616
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 36611-36616
-
-
MacFarlane, M.1
Merrison, W.2
Bratton, S.B.3
Cohen, G.M.4
|