Cytoplasmic p27Kip1 counteracts the pro-apoptotic function of the open conformation of PTEN by retention and destabilization of PTEN outside of the nucleus

Cellular Signalling

Volumn 24, Issue 2, 2012, Pages 577-587

  Andrés Pons, Amparo ^a,b   Gil, Anabel ^a   Oliver, María D ^a   Sotelo, Natalia Soledad ^a   Pulido, Rafael ^a  

^a CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

Author keywords

Apoptosis; Oncogenesis; P27Kip1; PTEN; Tumor suppression

Indexed keywords

CYCLIN DEPENDENT KINASE; CYCLIN DEPENDENT KINASE INHIBITOR 1B; CYCLINE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; BIOACCUMULATION; CARBOXY TERMINAL SEQUENCE; CELL NUCLEUS; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOPLASM; EMBRYO; HUMAN; HUMAN CELL; MAMMAL CELL; NONHUMAN; NUCLEOCYTOPLASMIC TRANSPORT; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN DEGRADATION; PROTEIN FUNCTION; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; PROTEIN TARGETING; PROTEIN TRANSPORT;

ANIMALS; APOPTOSIS; CELL CYCLE; CELL CYCLE PROTEINS; CELL NUCLEUS; CERCOPITHECUS AETHIOPS; COS CELLS; CYCLIN-DEPENDENT KINASE INHIBITOR P27; CYTOSOL; HEK293 CELLS; HUMANS; K562 CELLS; PHOSPHORYLATION; PLASMIDS; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN TRANSPORT; PTEN PHOSPHOHYDROLASE; SIGNAL TRANSDUCTION; TRANSFECTION; TUMOR NECROSIS FACTOR-ALPHA;

MAMMALIA;

EID: 83555165869     PISSN: 08986568     EISSN: 18733913     Source Type: Journal    
DOI: 10.1016/j.cellsig.2011.10.012     Document Type: Article

References (77)

1. Besson A., Dowdy S.F., Roberts J.M. Developmental Cell 2008, 9:159-169.
2. Chu I.M., Hengst L., Slingerland J.M. Nature Reviews. Cancer 2008, 8:253-267.
3. Lee J., Kim S.S. Experimental & Molecular Medicine 2009, 41:765-771.
4. Wander S.A., Zhao D., Slingerland J.M. Clinical Cancer Research 2010, 17:12-18.
5. Kaldis C., Aleem E. Cell Cycle 2005, 4:1491-1494.
6. Blain S.W. Cell Cycle 2008, 7:892-898.
7. Coqueret O. Trends in Cell Biology 2003, 13:65-70.
8. Borriello A., Cucciolla V., Oliva A., Zappia V., Della Ragione F. Cell Cycle 2007, 6:1053-1061.
9. Kaldis C. Cell 2007, 128:241-244.
10. Vervoorts J., Lüscher B. Cellular and Molecular Life Sciences 2008, 65:3255-3264.
11. Blagosklonny M.V. Cell Cycle 2002, 1:391-393.
12. Besson A., Assoian R.K., Roberts J.M. Nature Reviews. Cancer 2004, 4:948-955.
13. Sicinski P., Zacharek S., Kim C. Genes & Development 2007, 21:1703-1706.
14. Muraoka R.S., Lenferink A.E., Law B., Hamilton E., Brantley D.M., Roebuck L.R., Arteaga C.L. Molecular and Cellular Biology 2002, 22:2204-2219.
15. Gao H., Ouyang X., Banach-Petrosky W., Borowsky A.D., Lin Y., Kim M., Lee H., Shih W.J., Cardiff R.D., Shen M.M., Abate-Shen C. Proceedings of the National Academy of Sciences of the United States of America 2004, 101:17204-17209.
16. Besson A., Hwang H.C., Cicero S., Donovan S.L., Gurian-West M., Johnson D., Clurman B.E., Dyer M.A., Roberts J.M. Genes & Development 2007, 21:1731-1746.
17. Serres M.P., Zlotek-Zlotkiewicz E., Concha C., Gurian-West M., Daburon V., Roberts J.M., Besson A. Oncogene 2011, 30:2846-2858.
18. Blain S.W., Massagué J. Nature Medicine 2002, 8:1076-1078.
19. Mi Y.H., Cheong J.W., Kim J.Y., Eom J.Y., Lee S.T., Hahn J.S., Ko Y.W., Lee M.H. Cancer Research 2004, 64:5225-5231.
20. Rosen D.G., Yang G., Kai K.Q., Bast R.C., Gershenson D.M., Silva E.G., Liu J. Clinical Cancer Research 2005, 11:632-637.
21. Qi C.F., Xiang S., Shin M.S., Hao X., Lee C.H., Zhou J.X., Torrey T.A., Hartley J.W., Fredrickson T.N., Morse H.C. Leukemia Research 2006, 30:153-163.
22. Denicourt C., Saenz C.C., Datnow B., Cui X.S., Dowdy S.F. Cancer Research 2007, 67:9238-9243.
23. Fridberg M., Servin A., Anagnostaki L., Linderoth J., Berglund M., Söderberg O., Enblad G., Rosén A., Mustelin T., Jerkeman M., Persson J.L., Wingren A.G. Leukemia & Lymphoma 2007, 48:2221-2232.
24. McAllister S.S., Becker-Hapak M., Pintucci G., Pagano M., Dowdy S.F. Molecular and Cellular Biology 2003, 23:216-228.
25. Besson A., Gurian-West M., Schmidt A., Hall A., Roberts J.M. Genes & Development 2004, 18:862-876.
26. Wu F.Y., Wang S.E., Sanders M.E., Shin I., Rojo F., Baselga J., Arteaga C.L. Cancer Research 2006, 66:2162-2172.
27. Hoshino D., Tomari T., Nagano M., Koshikawa N., Seiki M. Journal of Biological Chemistry 2009, 284:27315-27326.
28. Liang J., Slingerland J.M. Cell Cycle 2003, 2:339-345.
29. Nakamura N., Ramaswamy S., Vazquez F., Signoretti S., Loda M., Sellers W.R. Molecular and Cellular Biology 2000, 20:8969-8982.
30. Mamillapalli R., Gavrilova N., Mihaylova V.T., Tsvetkov L.M., Wu H., Zhang H., Sun H. Current Biology 2001, 11:263-267.
31. Gericke A., Munson M., Ross A.H. Gene 2006, 374:1-9.
32. Bonifant C.L., Kim J.S., Waldman T. Journal of Cellular Biochemistry 2007, 102:878-885.
33. Tamguney T., Stokoe D. Journal of Cell Science 2007, 120:4071-4079.
34. Salmena L., Carracedo A., Pandolfi P.P. Cell 2008, 133:403-414.
35. Leslie N.R., Foti M. Trends Pharmacol. Sci. 2011, 32:131-140.
36. Freeman D.J., Li A.G., Wei G., Li H.H., Kertesz N., Lesche R., Whale A.D., Martinez-Diaz H., Rozengurt N., Cardiff R.D., Liu X., Wu H. Cancer Cell 2003, 3:117-130.
37. Chung J.H., Eng C. Cancer Research 2005, 65:8096-8100.
38. Gil A., Andrés-Pons A., Fernández E., Valiente M., Torres J., Cervera J., Pulido R. Molecular Biology of the Cell 2006, 17:4002-4013.
39. Shen W.H., Balajee A.S., Wang J., Wu H., Eng C., Pandolfi P.P., Yi Y. Cell 2007, 128:157-170.
40. Chang C.J., Mulholland D.J., Valamehr B., Mosessian S., Sellers W.R., Wu H. Molecular and Cellular Biology 2008, 28:3281-3289.
41. Song M.S., Carracedo A., Salmena L., Song S.J., Egia A., Malumbres M., Pandolfi P.P. Cell 2011, 144:187-199.
42. Carracedo A., Alimonti A., Pandolfi P.P. Cancer Research 2011, 71:629-633.
43. Baker S.J. Cell 2007, 128:25-28.
44. Gil A., Andrés-Pons A., Pulido R. Cell Death and Differentiation 2007, 14:395-399.
45. Planchon S.M., Waite K.A., Eng C. Journal of Cell Science 2008, 121:249-253.
46. Salmena L., Pandolfi P.P. Nature Reviews. Cancer 2007, 7:409-413.
47. Vazquez F., Devreotes P. Cell Cycle 2006, 5:1523-1527.
48. Leslie N.R., Batty I.H., Maccario L., Davidson L., Downes C.P. Oncogene 2008, 27:5464-5476.
49. Wang X., Jiang X. Oncogene 2008, 27:5454-5463.
50. Ross A.H., Gericke A. Proceedings of the National Academy of Sciences of the United States of America 2009, 106:1297-1298.
51. Muñoz-Alonso M.J., Acosta J.C., Richard C., Delgado M.D., Sedivy J., León J. Journal of Biological Chemistry 2005, 280:18120-18129.
52. Andrés-Pons A., Valiente M., Torres J., Gil A., Roglá I., Ripoll F., Cervera J., Pulido R. Cancer Letters 2005, 223:303-312.
53. Torres J., Rodriguez J., Myers M.P., Valiente M., Graves J.D., Tonks N.K., Pulido R. Journal of Biological Chemistry 2003, 278:30652-30660.
54. Ishida N., Hara T., Kamura T., Yoshida M., Nakayama K., Nakayama K.I. Journal of Biological Chemistry 2002, 277:14355-14358.
55. Odriozola L., Singh G., Hoang T., Chan A.M. Journal of Biological Chemistry 2007, 282:23306-23315.
56. Rahdar M., Inoue T., Meyer T., Zhang J., Vazquez F., Devreotes P.N. Proceedings of the National Academy of Sciences of the United States of America 2009, 106:480-485.
57. Lee J.O., Yang H., Georgescu M.M., Di Cristofano A., Maehama T., Shi Y., Dixon J.E., Pandolfi P., Pavletich N.P. Cell 1999, 99:323-334.
58. Georgescu M.M., Kirsch K.H., Kaloudis P., Yang H., Pavletich N.P., Hanafusa H. Cancer Research 2000, 60:7033-7038.
59. Vlach J., Hennecke S., Amati B. EMBO Journal 1997, 16:5334-5344.
60. Bienkiewicz E.A., Adkins J.N., Lumb K.J. Biochemistry 2002, 41:752-759.
61. Lacy E.R., Filippov I., Lewis W.S., Otieno S., Xiao L., Weiss S., Hengst L., Kriwacki R.W. Nature Structural and Molecular Biology 2004, 11:358-364.
62. Georgescu M.M., Kirsch K.H., Akagi T., Shihido T., Hanafusa H. Proceedings of the National Academy of Sciences of the United States of America 1999, 96:10182-10187.
63. Kwabi-Addo B., Giri D., Schmidt K., Podsypanina K., Parsons R., Greenberg N., Ittmann M. Proceedings of the National Academy of Sciences of the United States of America 2001, 98:11563-11568.
64. Andrés-Pons A., Rodríguez-Escudero I., Gil A., Blanco A., Vega A., Molina M., Pulido R., Cid V.J. Cancer Research 2007, 67:9731-9739.
65. Trotman L.C., Niki M., Dotan Z.A., Koutcher J.A., Di Cristofano A., Xiao A., Khoo A.S., Roy-Burman P., Greenberg N.M., Van Dyke T., Cordon-Cardo C., Pandolfi P.P. PLoS Biology 2003, 1:E59.
66. Alimonti A., Carracedo A., Clohessy J.G., Trotman L.C., Nardella C., Egia A., Salmena L., Sampieri K., Haveman W.J., Brogi E., Richardson A.L., Zhang J., Pandolfi P.P. Nature Genetics 2010, 42:454-458.
67. Trotman L.C., Wang X., Alimonti A., Chen Z., Teruya-Feldstein J., Yang H., Pavletich N.P., Carver B.S., Cordon-Cardo C., Erdjument-Bromage H., Tempst P., Chi S.G., Kim H.J., Misteli T., Jiang X., Pandolfi P.P. Cell 2007, 128:141-156.
68. Okahara F., Ikawa H., Kanaho Y., Maehama T. Journal of Biological Chemistry 2004, 279:45300-45303.
69. Valiente M., Andrés-Pons A., Gomar B., Torres J., Gil A., Tapparel C., Antonarakis S.E., Pulido R. Journal of Biological Chemistry 2005, 280:28936-28943.
70. Wang X., Shi Y., Wang J., Huang G., Jiang X. Biochemical Journal 2008, 414:221-229.
71. Vazquez F., Grossman S.R., Takahashi Y., Rokas M.V., Nakamura N., Sellers W.R. Journal of Biological Chemistry 2000, 276:48627-48630.
72. Torres J., Pulido R. Journal of Biological Chemistry 2001, 276:993-998.
73. Liu J.L., Sheng X., Hortobagyi Z.K., Mao Z., Gallick G.E., Yung W.K. Molecular and Cellular Biology 2005, 25:6211-6224.
74. Li Z., Dong X., Wang Z., Liu W., Deng N., Ding Y., Tang L., Hla T., Zeng R., Li L., Wu D. Nature Cell Biology 2005, 7:399-404.
75. Papakonstanti E.A., Ridley A.J., Vanhaesebroeck B. EMBO Journal 2007, 26:3050-3061.
76. Bashir T., Dorrello N.V., Amador V., Guardavaccaro D., Pagano M. Nature 2004, 428:190-193.
77. Wei W., Ayad N.G., Wan Y., Zhang G.J., Kirschner M.W., Kaelin W.G. Nature 2004, 428:194-198.