Phosphorylation-regulated cleavage of the tumor suppressor PTEN by caspase-3. Implications for the control of protein stability and PTEN-protein interactions

Journal of Biological Chemistry

Volumn 278, Issue 33, 2003, Pages 30652-30660

  Torres, Josema ^a,d   Rodriguez, Joe ^b   Myers, Michael P ^b   Valiente, Miguel ^a   Graves, Jonathan D ^c   Tonks, Nicholas K ^b   Pulido, Rafael ^a  

^a CENTRO DE INVESTIGACIÓN PRÍNCIPE FELIPE   (Spain)

^b Howard Hughes Medical Institute Cold Spring Harbor Laboratory Cold Spring Harbor   (United States)

^c UNIVERSITY OF WASHINGTON MEDICAL CENTER   (United States)

^d IMPERIAL CANCER RESEARCH FUND   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; MOLECULES; PROTEINS; TUMORS;

TUMOR SUPPRESSORS;

BIOCHEMISTRY;

CASPASE 3; CYCLOHEXIMIDE; PHOSPHATIDYLINOSITOL 3,4,5 TRISPHOSPHATE 3 PHOSPHATASE; TUMOR NECROSIS FACTOR ALPHA;

ANIMAL CELL; APOPTOSIS; ARTICLE; CELL FRACTIONATION; CELL GROWTH; CONTROLLED STUDY; CYTOLYSIS; ENZYME PHOSPHORYLATION; GENETIC TRANSFECTION; NONHUMAN; PLASMID; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN STABILITY; TUMOR SUPPRESSOR GENE;

ACTIVIN RECEPTORS, TYPE II; ANIMALS; APOPTOSIS; CARRIER PROTEINS; CASEIN KINASE II; CASPASE 3; CASPASES; COS CELLS; HUMANS; KIDNEY; MUTAGENESIS; PHOSPHORIC MONOESTER HYDROLASES; PHOSPHORYLATION; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTEINS; PTEN PHOSPHOHYDROLASE; TUMOR SUPPRESSOR PROTEINS;

ANIMALIA;

EID: 0042232478     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M212610200     Document Type: Article

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