메뉴 건너뛰기




Volumn 32, Issue 12, 2011, Pages 603-611

Deciphering the role of Th17 cells in human disease

Author keywords

[No Author keywords available]

Indexed keywords

CD8 ANTIGEN; CHEMOKINE RECEPTOR CCR6; CXCL9 CHEMOKINE; ETANERCEPT; GAMMA INTERFERON; GAMMA INTERFERON RECEPTOR 1; GRANULOCYTE COLONY STIMULATING FACTOR; HLA DR ANTIGEN; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; INTERLEUKIN 10; INTERLEUKIN 17; INTERLEUKIN 17F; INTERLEUKIN 1BETA; INTERLEUKIN 2 RECEPTOR ALPHA; INTERLEUKIN 22; INTERLEUKIN 23; INTERLEUKIN 23 RECEPTOR; INTERLEUKIN 4 RECEPTOR; INTERLEUKIN 6; INTERLEUKIN 8; INTERLEUKIN 9; MACROPHAGE DERIVED CHEMOKINE; MONOCLONAL ANTIBODY; PROGRAMMED DEATH 1 LIGAND 1; RETINOID RELATED ORPHAN RECEPTOR GAMMA; TRANSCRIPTION FACTOR FOXP3; TRANSCRIPTION FACTOR T BET; TRANSFORMING GROWTH FACTOR BETA; TUMOR NECROSIS FACTOR ALPHA; UNINDEXED DRUG;

EID: 81355148789     PISSN: 14714906     EISSN: 14714981     Source Type: Journal    
DOI: 10.1016/j.it.2011.08.003     Document Type: Review
Times cited : (188)

References (110)
  • 1
    • 34547734621 scopus 로고    scopus 로고
    • Phenotypic and functional features of human Th17 cells
    • Annunziato F., et al. Phenotypic and functional features of human Th17 cells. J. Exp. Med. 2007, 204:1849-1861.
    • (2007) J. Exp. Med. , vol.204 , pp. 1849-1861
    • Annunziato, F.1
  • 2
    • 49249135394 scopus 로고    scopus 로고
    • Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor
    • Cosmi L., et al. Human interleukin 17-producing cells originate from a CD161+CD4+ T cell precursor. J. Exp. Med. 2008, 205:1903-1916.
    • (2008) J. Exp. Med. , vol.205 , pp. 1903-1916
    • Cosmi, L.1
  • 3
    • 63449133361 scopus 로고    scopus 로고
    • Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation
    • Kleinschek M.A., et al. Circulating and gut-resident human Th17 cells express CD161 and promote intestinal inflammation. J. Exp. Med. 2009, 206:525-534.
    • (2009) J. Exp. Med. , vol.206 , pp. 525-534
    • Kleinschek, M.A.1
  • 4
    • 69849107597 scopus 로고    scopus 로고
    • Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments
    • Kryczek I., et al. Phenotype, distribution, generation, and functional and clinical relevance of Th17 cells in the human tumor environments. Blood 2009, 114:1141-1149.
    • (2009) Blood , vol.114 , pp. 1141-1149
    • Kryczek, I.1
  • 5
    • 58149316658 scopus 로고    scopus 로고
    • Induction of IL-17+ T cell trafficking and development by IFN-gamma: mechanism and pathological relevance in psoriasis
    • Kryczek I., et al. Induction of IL-17+ T cell trafficking and development by IFN-gamma: mechanism and pathological relevance in psoriasis. J. Immunol. 2008, 181:4733-4741.
    • (2008) J. Immunol. , vol.181 , pp. 4733-4741
    • Kryczek, I.1
  • 6
    • 79955040909 scopus 로고    scopus 로고
    • IL-17+ Regulatory T cells in the microenvironments of chronic inflammation and cancer
    • Kryczek I., et al. IL-17+ Regulatory T cells in the microenvironments of chronic inflammation and cancer. J. Immunol. 2011, 186:4388-4395.
    • (2011) J. Immunol. , vol.186 , pp. 4388-4395
    • Kryczek, I.1
  • 7
    • 77956124982 scopus 로고    scopus 로고
    • CD161 is a marker of all human IL-17-producing T-cell subsets and is induced by RORC
    • Maggi L., et al. CD161 is a marker of all human IL-17-producing T-cell subsets and is induced by RORC. Eur. J. Immunol. 2010, 40:2174-2181.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 2174-2181
    • Maggi, L.1
  • 8
    • 42649115767 scopus 로고    scopus 로고
    • TH17 cells in development: an updated view of their molecular identity and genetic programming
    • Dong C. TH17 cells in development: an updated view of their molecular identity and genetic programming. Nat. Rev. Immunol. 2008, 8:337-348.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 337-348
    • Dong, C.1
  • 9
    • 55149090692 scopus 로고    scopus 로고
    • Th17 cytokines and mucosal immunity
    • Dubin P.J., Kolls J.K. Th17 cytokines and mucosal immunity. Immunol. Rev. 2008, 226:160-171.
    • (2008) Immunol. Rev. , vol.226 , pp. 160-171
    • Dubin, P.J.1    Kolls, J.K.2
  • 10
    • 45749101727 scopus 로고    scopus 로고
    • Induction and effector functions of T(H)17 cells
    • Bettelli E., et al. Induction and effector functions of T(H)17 cells. Nature 2008, 453:1051-1057.
    • (2008) Nature , vol.453 , pp. 1051-1057
    • Bettelli, E.1
  • 11
    • 72949106340 scopus 로고    scopus 로고
    • Interplay between the TH17 and TReg cell lineages: a (co-)evolutionary perspective
    • Weaver C.T., Hatton R.D. Interplay between the TH17 and TReg cell lineages: a (co-)evolutionary perspective. Nat. Rev. Immunol. 2009, 9:883-889.
    • (2009) Nat. Rev. Immunol. , vol.9 , pp. 883-889
    • Weaver, C.T.1    Hatton, R.D.2
  • 12
    • 77950196277 scopus 로고    scopus 로고
    • T(H)17 cells in tumour immunity and immunotherapy
    • Zou W., Restifo N.P. T(H)17 cells in tumour immunity and immunotherapy. Nat. Rev. Immunol. 2010, 10:248-256.
    • (2010) Nat. Rev. Immunol. , vol.10 , pp. 248-256
    • Zou, W.1    Restifo, N.P.2
  • 13
    • 77954948735 scopus 로고    scopus 로고
    • Effector T cell plasticity: flexibility in the face of changing circumstances
    • Murphy K.M., Stockinger B. Effector T cell plasticity: flexibility in the face of changing circumstances. Nat. Immunol. 2010, 11:674-680.
    • (2010) Nat. Immunol. , vol.11 , pp. 674-680
    • Murphy, K.M.1    Stockinger, B.2
  • 14
    • 58149251898 scopus 로고    scopus 로고
    • Late developmental plasticity in the T helper 17 lineage
    • Lee Y.K., et al. Late developmental plasticity in the T helper 17 lineage. Immunity 2009, 30:92-107.
    • (2009) Immunity , vol.30 , pp. 92-107
    • Lee, Y.K.1
  • 15
    • 73149118287 scopus 로고    scopus 로고
    • Identification of a novel subset of human circulating memory CD4(+) T cells that produce both IL-17A and IL-4
    • e221-224
    • Cosmi L., et al. Identification of a novel subset of human circulating memory CD4(+) T cells that produce both IL-17A and IL-4. J. Allergy Clin. Immunol. 2010, 125:222-230. e221-224.
    • (2010) J. Allergy Clin. Immunol. , vol.125 , pp. 222-230
    • Cosmi, L.1
  • 16
    • 33645853780 scopus 로고    scopus 로고
    • B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma
    • Kryczek I., et al. B7-H4 expression identifies a novel suppressive macrophage population in human ovarian carcinoma. J. Exp. Med. 2006, 203:871-881.
    • (2006) J. Exp. Med. , vol.203 , pp. 871-881
    • Kryczek, I.1
  • 17
    • 0035658072 scopus 로고    scopus 로고
    • Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells
    • Zou W., et al. Stromal-derived factor-1 in human tumors recruits and alters the function of plasmacytoid precursor dendritic cells. Nat. Med. 2001, 7:1339-1346.
    • (2001) Nat. Med. , vol.7 , pp. 1339-1346
    • Zou, W.1
  • 18
    • 20444485236 scopus 로고    scopus 로고
    • Plasmacytoid dendritic cells induce CD8+ regulatory T cells in human ovarian carcinoma
    • Wei S., et al. Plasmacytoid dendritic cells induce CD8+ regulatory T cells in human ovarian carcinoma. Cancer Res. 2005, 65:5020-5026.
    • (2005) Cancer Res. , vol.65 , pp. 5020-5026
    • Wei, S.1
  • 19
    • 0038273853 scopus 로고    scopus 로고
    • Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity
    • Curiel T.J., et al. Blockade of B7-H1 improves myeloid dendritic cell-mediated antitumor immunity. Nat. Med. 2003, 9:562-567.
    • (2003) Nat. Med. , vol.9 , pp. 562-567
    • Curiel, T.J.1
  • 20
    • 4644237613 scopus 로고    scopus 로고
    • Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival
    • Curiel T.J., et al. Specific recruitment of regulatory T cells in ovarian carcinoma fosters immune privilege and predicts reduced survival. Nat. Med. 2004, 10:942-949.
    • (2004) Nat. Med. , vol.10 , pp. 942-949
    • Curiel, T.J.1
  • 21
    • 16844379997 scopus 로고    scopus 로고
    • Immunosuppressive networks in the tumour environment and their therapeutic relevance
    • Zou W. Immunosuppressive networks in the tumour environment and their therapeutic relevance. Nat. Rev. Cancer 2005, 5:263-274.
    • (2005) Nat. Rev. Cancer , vol.5 , pp. 263-274
    • Zou, W.1
  • 22
    • 33645286546 scopus 로고    scopus 로고
    • Regulatory T cells, tumour immunity and immunotherapy
    • Zou W. Regulatory T cells, tumour immunity and immunotherapy. Nat. Rev. Immunol. 2006, 6:295-307.
    • (2006) Nat. Rev. Immunol. , vol.6 , pp. 295-307
    • Zou, W.1
  • 23
    • 44349150012 scopus 로고    scopus 로고
    • Inhibitory B7-family molecules in the tumour microenvironment
    • Zou W., Chen L. Inhibitory B7-family molecules in the tumour microenvironment. Nat. Rev. Immunol. 2008, 8:467-477.
    • (2008) Nat. Rev. Immunol. , vol.8 , pp. 467-477
    • Zou, W.1    Chen, L.2
  • 24
    • 67651094058 scopus 로고    scopus 로고
    • Endogenous IL-17 contributes to reduced tumor growth and metastasis
    • Kryczek I., et al. Endogenous IL-17 contributes to reduced tumor growth and metastasis. Blood 2009, 114:357-359.
    • (2009) Blood , vol.114 , pp. 357-359
    • Kryczek, I.1
  • 25
    • 34249806717 scopus 로고    scopus 로고
    • Cutting edge: Th17 and regulatory T cell dynamics and the regulation by IL-2 in the tumor microenvironment
    • Kryczek I., et al. Cutting edge: Th17 and regulatory T cell dynamics and the regulation by IL-2 in the tumor microenvironment. J. Immunol. 2007, 178:6730-6733.
    • (2007) J. Immunol. , vol.178 , pp. 6730-6733
    • Kryczek, I.1
  • 26
    • 34548651152 scopus 로고    scopus 로고
    • Cutting edge: opposite effects of IL-1 and IL-2 on the regulation of IL-17+ T cell pool IL-1 subverts IL-2-mediated suppression
    • Kryczek I., et al. Cutting edge: opposite effects of IL-1 and IL-2 on the regulation of IL-17+ T cell pool IL-1 subverts IL-2-mediated suppression. J. Immunol. 2007, 179:1423-1426.
    • (2007) J. Immunol. , vol.179 , pp. 1423-1426
    • Kryczek, I.1
  • 27
    • 48849103649 scopus 로고    scopus 로고
    • Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing
    • Sfanos K.S., et al. Phenotypic analysis of prostate-infiltrating lymphocytes reveals TH17 and Treg skewing. Clin. Cancer Res. 2008, 14:3254-3261.
    • (2008) Clin. Cancer Res. , vol.14 , pp. 3254-3261
    • Sfanos, K.S.1
  • 28
    • 78650636066 scopus 로고    scopus 로고
    • Generation and differentiation of IL-17-producing CD4+ T cells in malignant pleural effusion
    • Ye Z.J., et al. Generation and differentiation of IL-17-producing CD4+ T cells in malignant pleural effusion. J. Immunol. 2010, 185:6348-6354.
    • (2010) J. Immunol. , vol.185 , pp. 6348-6354
    • Ye, Z.J.1
  • 29
    • 79952465385 scopus 로고    scopus 로고
    • Intratumoral expression of IL-17 and its prognostic role in gastric adenocarcinoma patients
    • Chen J.G., et al. Intratumoral expression of IL-17 and its prognostic role in gastric adenocarcinoma patients. Int. J. Biol. Sci. 2011, 7:53-60.
    • (2011) Int. J. Biol. Sci. , vol.7 , pp. 53-60
    • Chen, J.G.1
  • 30
    • 76749156695 scopus 로고    scopus 로고
    • Different subsets of tumor infiltrating lymphocytes correlate with NPC progression in different ways
    • Zhang Y.L., et al. Different subsets of tumor infiltrating lymphocytes correlate with NPC progression in different ways. Mol. Cancer 2010, 9:4.
    • (2010) Mol. Cancer , vol.9 , pp. 4
    • Zhang, Y.L.1
  • 31
    • 68249133652 scopus 로고    scopus 로고
    • Pretreatment frequency of circulating IL-17+ CD4+ T-cells, but not Tregs, correlates with clinical response to whole-cell vaccination in prostate cancer patients
    • Derhovanessian E., et al. Pretreatment frequency of circulating IL-17+ CD4+ T-cells, but not Tregs, correlates with clinical response to whole-cell vaccination in prostate cancer patients. Int. J. Cancer 2009, 125:1372-1379.
    • (2009) Int. J. Cancer , vol.125 , pp. 1372-1379
    • Derhovanessian, E.1
  • 32
    • 69949120571 scopus 로고    scopus 로고
    • A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses
    • Wu S., et al. A human colonic commensal promotes colon tumorigenesis via activation of T helper type 17 T cell responses. Nat. Med. 2009, 15:1016-1022.
    • (2009) Nat. Med. , vol.15 , pp. 1016-1022
    • Wu, S.1
  • 33
    • 78649544524 scopus 로고    scopus 로고
    • The transient nature of the Th17 phenotype
    • Annunziato F., Romagnani S. The transient nature of the Th17 phenotype. Eur. J. Immunol. 2010, 40:3312-3316.
    • (2010) Eur. J. Immunol. , vol.40 , pp. 3312-3316
    • Annunziato, F.1    Romagnani, S.2
  • 34
    • 60549086638 scopus 로고    scopus 로고
    • Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells
    • Martin-Orozco N., et al. Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells. Eur. J. Immunol. 2009, 39:216-224.
    • (2009) Eur. J. Immunol. , vol.39 , pp. 216-224
    • Martin-Orozco, N.1
  • 35
    • 67650650890 scopus 로고    scopus 로고
    • Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice
    • Bending D., et al. Highly purified Th17 cells from BDC2.5NOD mice convert into Th1-like cells in NOD/SCID recipient mice. J. Clin. Invest. 2009, 119:565-572.
    • (2009) J. Clin. Invest. , vol.119 , pp. 565-572
    • Bending, D.1
  • 36
    • 77957032994 scopus 로고    scopus 로고
    • Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment
    • Nistala K., et al. Th17 plasticity in human autoimmune arthritis is driven by the inflammatory environment. Proc. Natl. Acad. Sci. U.S.A. 2010, 107:14751-14756.
    • (2010) Proc. Natl. Acad. Sci. U.S.A. , vol.107 , pp. 14751-14756
    • Nistala, K.1
  • 37
    • 78649819162 scopus 로고    scopus 로고
    • Alphav Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice
    • Acharya M., et al. alphav Integrin expression by DCs is required for Th17 cell differentiation and development of experimental autoimmune encephalomyelitis in mice. J. Clin. Invest. 2010, 120:4445-4452.
    • (2010) J. Clin. Invest. , vol.120 , pp. 4445-4452
    • Acharya, M.1
  • 38
    • 58149331211 scopus 로고    scopus 로고
    • Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells
    • Zaba L.C., et al. Psoriasis is characterized by accumulation of immunostimulatory and Th1/Th17 cell-polarizing myeloid dendritic cells. J. Invest. Dermatol. 2009, 129:79-88.
    • (2009) J. Invest. Dermatol. , vol.129 , pp. 79-88
    • Zaba, L.C.1
  • 39
    • 0032939156 scopus 로고    scopus 로고
    • Human interleukin-17: a T cell-derived proinflammatory cytokine produced by the rheumatoid synovium
    • Chabaud M., et al. Human interleukin-17: a T cell-derived proinflammatory cytokine produced by the rheumatoid synovium. Arthritis Rheum. 1999, 42:963-970.
    • (1999) Arthritis Rheum. , vol.42 , pp. 963-970
    • Chabaud, M.1
  • 40
    • 0034161692 scopus 로고    scopus 로고
    • High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism
    • Ziolkowska M., et al. High levels of IL-17 in rheumatoid arthritis patients: IL-15 triggers in vitro IL-17 production via cyclosporin A-sensitive mechanism. J. Immunol. 2000, 164:2832-2838.
    • (2000) J. Immunol. , vol.164 , pp. 2832-2838
    • Ziolkowska, M.1
  • 41
    • 26044455144 scopus 로고    scopus 로고
    • Expression of IL-17 homologs and their receptors in the synovial cells of rheumatoid arthritis patients
    • Hwang S.Y., Kim H.Y. Expression of IL-17 homologs and their receptors in the synovial cells of rheumatoid arthritis patients. Mol. Cells 2005, 19:180-184.
    • (2005) Mol. Cells , vol.19 , pp. 180-184
    • Hwang, S.Y.1    Kim, H.Y.2
  • 42
    • 77957689108 scopus 로고    scopus 로고
    • Role of Th17 cells in human autoimmune arthritis
    • Leipe J., et al. Role of Th17 cells in human autoimmune arthritis. Arthritis Rheum. 2010, 62:2876-2885.
    • (2010) Arthritis Rheum. , vol.62 , pp. 2876-2885
    • Leipe, J.1
  • 43
    • 77958006636 scopus 로고    scopus 로고
    • Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritis
    • Cascao R., et al. Identification of a cytokine network sustaining neutrophil and Th17 activation in untreated early rheumatoid arthritis. Arthritis Res. Ther. 2010, 12:R196.
    • (2010) Arthritis Res. Ther. , vol.12
    • Cascao, R.1
  • 44
    • 78650764391 scopus 로고    scopus 로고
    • Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production
    • van Hamburg J.P., et al. Th17 cells, but not Th1 cells, from patients with early rheumatoid arthritis are potent inducers of matrix metalloproteinases and proinflammatory cytokines upon synovial fibroblast interaction, including autocrine interleukin-17A production. Arthritis Rheum. 2011, 63:73-83.
    • (2011) Arthritis Rheum. , vol.63 , pp. 73-83
    • van Hamburg, J.P.1
  • 45
    • 79953310900 scopus 로고    scopus 로고
    • Effects of interleukin (IL)-17A and IL-17F in human rheumatoid arthritis synoviocytes
    • Hot A., Miossec P. Effects of interleukin (IL)-17A and IL-17F in human rheumatoid arthritis synoviocytes. Ann. Rheum Dis. 2011, 70:727-732.
    • (2011) Ann. Rheum Dis. , vol.70 , pp. 727-732
    • Hot, A.1    Miossec, P.2
  • 46
    • 33646349199 scopus 로고    scopus 로고
    • Synovial membrane cytokine expression is predictive of joint damage progression in rheumatoid arthritis: a two-year prospective study (the DAMAGE study cohort)
    • Kirkham B.W., et al. Synovial membrane cytokine expression is predictive of joint damage progression in rheumatoid arthritis: a two-year prospective study (the DAMAGE study cohort). Arthritis Rheum. 2006, 54:1122-1131.
    • (2006) Arthritis Rheum. , vol.54 , pp. 1122-1131
    • Kirkham, B.W.1
  • 47
    • 79551595156 scopus 로고    scopus 로고
    • A polymorphism in the interleukin-4 receptor affects the ability of interleukin-4 to regulate Th17 cells: a possible immunoregulatory mechanism for genetic control of the severity of rheumatoid arthritis
    • Wallis S.K., et al. A polymorphism in the interleukin-4 receptor affects the ability of interleukin-4 to regulate Th17 cells: a possible immunoregulatory mechanism for genetic control of the severity of rheumatoid arthritis. Arthritis Res. Ther. 2011, 13:R15.
    • (2011) Arthritis Res. Ther. , vol.13
    • Wallis, S.K.1
  • 48
    • 34247570854 scopus 로고    scopus 로고
    • Cells of the synovium in rheumatoid arthritis. T lymphocytes
    • Lundy S.K., et al. Cells of the synovium in rheumatoid arthritis. T lymphocytes. Arthritis Res. Ther. 2007, 9:202.
    • (2007) Arthritis Res. Ther. , vol.9 , pp. 202
    • Lundy, S.K.1
  • 49
    • 36348952001 scopus 로고    scopus 로고
    • Molecular interactions between T cells and fibroblast-like synoviocytes: role of membrane tumor necrosis factor-alpha on cytokine-activated T cells
    • Tran C.N., et al. Molecular interactions between T cells and fibroblast-like synoviocytes: role of membrane tumor necrosis factor-alpha on cytokine-activated T cells. Am. J. Pathol. 2007, 171:1588-1598.
    • (2007) Am. J. Pathol. , vol.171 , pp. 1588-1598
    • Tran, C.N.1
  • 50
    • 33751521013 scopus 로고    scopus 로고
    • Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction
    • Sato K., et al. Th17 functions as an osteoclastogenic helper T cell subset that links T cell activation and bone destruction. J. Exp. Med. 2006, 203:2673-2682.
    • (2006) J. Exp. Med. , vol.203 , pp. 2673-2682
    • Sato, K.1
  • 51
    • 79951846831 scopus 로고    scopus 로고
    • Th17 cells, not IL-17+ {gamma}{delta} T cells, drive arthritic bone destruction in mice and humans
    • Pollinger B., et al. Th17 cells, not IL-17+ {gamma}{delta} T cells, drive arthritic bone destruction in mice and humans. J. Immunol. 2011, 186:2602-2612.
    • (2011) J. Immunol. , vol.186 , pp. 2602-2612
    • Pollinger, B.1
  • 52
    • 78651371338 scopus 로고    scopus 로고
    • Synovial fluid-derived T helper 17 cells correlate with inflammatory activity in arthritis, irrespectively of diagnosis
    • Zizzo G., et al. Synovial fluid-derived T helper 17 cells correlate with inflammatory activity in arthritis, irrespectively of diagnosis. Clin. Immunol. 2011, 138:107-116.
    • (2011) Clin. Immunol. , vol.138 , pp. 107-116
    • Zizzo, G.1
  • 53
    • 79961117793 scopus 로고    scopus 로고
    • Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritis
    • Cosmi L., et al. Evidence of the transient nature of the Th17 phenotype of CD4+CD161+ T cells in the synovial fluid of patients with juvenile idiopathic arthritis. Arthritis Rheum. 2011, 63:2504-2515.
    • (2011) Arthritis Rheum. , vol.63 , pp. 2504-2515
    • Cosmi, L.1
  • 54
    • 80555154916 scopus 로고    scopus 로고
    • Sensitivity and resistance to regulation by IL-4 during Th17 maturatio
    • in press
    • Cooney, L.A. et al. (2011) Sensitivity and resistance to regulation by IL-4 during Th17 maturation. J. Immunol., in press.
    • (2011) J. Immunol.
    • Cooney, L.A.1
  • 55
    • 0344389016 scopus 로고    scopus 로고
    • Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis
    • Matusevicius D., et al. Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis. Mult. Scler. 1999, 5:101-104.
    • (1999) Mult. Scler. , vol.5 , pp. 101-104
    • Matusevicius, D.1
  • 56
    • 21044448355 scopus 로고    scopus 로고
    • Intrathecal activation of the IL-17/IL-8 axis in opticospinal multiple sclerosis
    • Ishizu T., et al. Intrathecal activation of the IL-17/IL-8 axis in opticospinal multiple sclerosis. Brain 2005, 128:988-1002.
    • (2005) Brain , vol.128 , pp. 988-1002
    • Ishizu, T.1
  • 57
    • 47249128991 scopus 로고    scopus 로고
    • Th17 cells in human disease
    • Tesmer L.A., et al. Th17 cells in human disease. Immunol. Rev. 2008, 223:87-113.
    • (2008) Immunol. Rev. , vol.223 , pp. 87-113
    • Tesmer, L.A.1
  • 58
    • 70449716915 scopus 로고    scopus 로고
    • MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis
    • Du C., et al. MicroRNA miR-326 regulates TH-17 differentiation and is associated with the pathogenesis of multiple sclerosis. Nat. Immunol. 2009, 10:1252-1259.
    • (2009) Nat. Immunol. , vol.10 , pp. 1252-1259
    • Du, C.1
  • 59
    • 34948909646 scopus 로고    scopus 로고
    • Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation
    • Kebir H., et al. Human TH17 lymphocytes promote blood-brain barrier disruption and central nervous system inflammation. Nat. Med. 2007, 13:1173-1175.
    • (2007) Nat. Med. , vol.13 , pp. 1173-1175
    • Kebir, H.1
  • 60
    • 36248965294 scopus 로고    scopus 로고
    • TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology
    • McGeachy M.J., et al. TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology. Nat. Immunol. 2007, 8:1390-1397.
    • (2007) Nat. Immunol. , vol.8 , pp. 1390-1397
    • McGeachy, M.J.1
  • 61
    • 79251584980 scopus 로고    scopus 로고
    • Glycogen synthase kinase-3 is an early determinant in the differentiation of pathogenic Th17 cells
    • Beurel E., et al. Glycogen synthase kinase-3 is an early determinant in the differentiation of pathogenic Th17 cells. J. Immunol. 2011, 186:1391-1398.
    • (2011) J. Immunol. , vol.186 , pp. 1391-1398
    • Beurel, E.1
  • 62
    • 79851512548 scopus 로고    scopus 로고
    • PPARdelta deficient mice develop elevated Th1/Th17 responses and prolonged experimental autoimmune encephalomyelitis
    • Kanakasabai S., et al. PPARdelta deficient mice develop elevated Th1/Th17 responses and prolonged experimental autoimmune encephalomyelitis. Brain Res. 2011, 1376:101-112.
    • (2011) Brain Res. , vol.1376 , pp. 101-112
    • Kanakasabai, S.1
  • 63
    • 77956242237 scopus 로고    scopus 로고
    • Central nervous system (CNS)-resident natural killer cells suppress Th17 responses and CNS autoimmune pathology
    • Hao J., et al. Central nervous system (CNS)-resident natural killer cells suppress Th17 responses and CNS autoimmune pathology. J. Exp. Med. 2010, 207:1907-1921.
    • (2010) J. Exp. Med. , vol.207 , pp. 1907-1921
    • Hao, J.1
  • 64
    • 77954827808 scopus 로고    scopus 로고
    • Induction of a regulatory B cell population in experimental allergic encephalomyelitis by alteration of the gut commensal microflora
    • Ochoa-Reparaz J., et al. Induction of a regulatory B cell population in experimental allergic encephalomyelitis by alteration of the gut commensal microflora. Gut. Microbes 2010, 1:103-108.
    • (2010) Gut. Microbes , vol.1 , pp. 103-108
    • Ochoa-Reparaz, J.1
  • 65
    • 78649807601 scopus 로고    scopus 로고
    • Expression of alphavbeta8 integrin on dendritic cells regulates Th17 cell development and experimental autoimmune encephalomyelitis in mice
    • Melton A.C., et al. Expression of alphavbeta8 integrin on dendritic cells regulates Th17 cell development and experimental autoimmune encephalomyelitis in mice. J. Clin. Invest. 2010, 120:4436-4444.
    • (2010) J. Clin. Invest. , vol.120 , pp. 4436-4444
    • Melton, A.C.1
  • 66
    • 33646397611 scopus 로고    scopus 로고
    • IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6
    • Yen D., et al. IL-23 is essential for T cell-mediated colitis and promotes inflammation via IL-17 and IL-6. J. Clin. Invest. 2006, 116:1310-1316.
    • (2006) J. Clin. Invest. , vol.116 , pp. 1310-1316
    • Yen, D.1
  • 67
    • 33750505009 scopus 로고    scopus 로고
    • Interleukin-23 drives innate and T cell-mediated intestinal inflammation
    • Hue S., et al. Interleukin-23 drives innate and T cell-mediated intestinal inflammation. J. Exp. Med. 2006, 203:2473-2483.
    • (2006) J. Exp. Med. , vol.203 , pp. 2473-2483
    • Hue, S.1
  • 68
    • 33750530394 scopus 로고    scopus 로고
    • IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis
    • Kullberg M.C., et al. IL-23 plays a key role in Helicobacter hepaticus-induced T cell-dependent colitis. J. Exp. Med. 2006, 203:2485-2494.
    • (2006) J. Exp. Med. , vol.203 , pp. 2485-2494
    • Kullberg, M.C.1
  • 69
    • 33845340501 scopus 로고    scopus 로고
    • A genome-wide association study identifies IL23R as an inflammatory bowel disease gene
    • Duerr R.H., et al. A genome-wide association study identifies IL23R as an inflammatory bowel disease gene. Science 2006, 314:1461-1463.
    • (2006) Science , vol.314 , pp. 1461-1463
    • Duerr, R.H.1
  • 70
    • 0037299902 scopus 로고    scopus 로고
    • Upregulation of interleukin-12 and -17 in active inflammatory bowel disease
    • Nielsen O.H., et al. Upregulation of interleukin-12 and -17 in active inflammatory bowel disease. Scand. J. Gastroenterol. 2003, 38:180-185.
    • (2003) Scand. J. Gastroenterol. , vol.38 , pp. 180-185
    • Nielsen, O.H.1
  • 71
    • 72549107316 scopus 로고    scopus 로고
    • Differential regulation of interleukin 17 and interferon gamma production in inflammatory bowel disease
    • Rovedatti L., et al. Differential regulation of interleukin 17 and interferon gamma production in inflammatory bowel disease. Gut 2009, 58:1629-1636.
    • (2009) Gut , vol.58 , pp. 1629-1636
    • Rovedatti, L.1
  • 72
    • 78649936808 scopus 로고    scopus 로고
    • Differential mucosal expression of Th17-related genes between the inflamed colon and ileum of patients with inflammatory bowel disease
    • Bogaert S., et al. Differential mucosal expression of Th17-related genes between the inflamed colon and ileum of patients with inflammatory bowel disease. BMC Immunol. 2010, 11:61.
    • (2010) BMC Immunol. , vol.11 , pp. 61
    • Bogaert, S.1
  • 73
    • 33847390444 scopus 로고    scopus 로고
    • Phenotype and effector function of CC chemokine receptor 9-expressing lymphocytes in small intestinal Crohn's disease
    • Saruta M., et al. Phenotype and effector function of CC chemokine receptor 9-expressing lymphocytes in small intestinal Crohn's disease. J. Immunol. 2007, 178:3293-3300.
    • (2007) J. Immunol. , vol.178 , pp. 3293-3300
    • Saruta, M.1
  • 74
    • 0026689516 scopus 로고
    • Tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-6 expression in inflammatory bowel disease
    • Stevens C., et al. Tumor necrosis factor-alpha, interleukin-1 beta, and interleukin-6 expression in inflammatory bowel disease. Dig. Dis. Sci. 1992, 37:818-826.
    • (1992) Dig. Dis. Sci. , vol.37 , pp. 818-826
    • Stevens, C.1
  • 75
    • 0027451455 scopus 로고
    • Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease
    • Reinecker H.C., et al. Enhanced secretion of tumour necrosis factor-alpha, IL-6, and IL-1 beta by isolated lamina propria mononuclear cells from patients with ulcerative colitis and Crohn's disease. Clin. Exp. Immunol. 1993, 94:174-181.
    • (1993) Clin. Exp. Immunol. , vol.94 , pp. 174-181
    • Reinecker, H.C.1
  • 76
    • 26444433211 scopus 로고    scopus 로고
    • Interleukin-17 is a potent immuno-modulator and regulator of normal human intestinal epithelial cell growth
    • Schwartz S., et al. Interleukin-17 is a potent immuno-modulator and regulator of normal human intestinal epithelial cell growth. Biochem. Biophys Res. Commun. 2005, 337:505-509.
    • (2005) Biochem. Biophys Res. Commun. , vol.337 , pp. 505-509
    • Schwartz, S.1
  • 77
    • 33846889522 scopus 로고    scopus 로고
    • A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis
    • Krueger G.G., et al. A human interleukin-12/23 monoclonal antibody for the treatment of psoriasis. N. Engl. J. Med. 2007, 356:580-592.
    • (2007) N. Engl. J. Med. , vol.356 , pp. 580-592
    • Krueger, G.G.1
  • 78
    • 8344284998 scopus 로고    scopus 로고
    • Anti-interleukin-12 antibody for active Crohn's disease
    • Mannon P.J., et al. Anti-interleukin-12 antibody for active Crohn's disease. N. Engl. J. Med. 2004, 351:2069-2079.
    • (2004) N. Engl. J. Med. , vol.351 , pp. 2069-2079
    • Mannon, P.J.1
  • 79
    • 33745553245 scopus 로고    scopus 로고
    • A phase 1/2A trial of STA 5326, an oral interleukin-12/23 inhibitor, in patients with active moderate to severe Crohn's disease
    • Burakoff R., et al. A phase 1/2A trial of STA 5326, an oral interleukin-12/23 inhibitor, in patients with active moderate to severe Crohn's disease. Inflamm. Bowel Dis. 2006, 12:558-565.
    • (2006) Inflamm. Bowel Dis. , vol.12 , pp. 558-565
    • Burakoff, R.1
  • 80
    • 33749151636 scopus 로고    scopus 로고
    • An anti-IL-12p40 antibody down-regulates type 1 cytokines, chemokines, and IL-12/IL-23 in psoriasis
    • Toichi E., et al. An anti-IL-12p40 antibody down-regulates type 1 cytokines, chemokines, and IL-12/IL-23 in psoriasis. J. Immunol. 2006, 177:4917-4926.
    • (2006) J. Immunol. , vol.177 , pp. 4917-4926
    • Toichi, E.1
  • 81
    • 79954997896 scopus 로고    scopus 로고
    • B cells as a therapeutic target for IFN-{beta} in relapsing-remitting multiple sclerosis
    • Ramgolam V.S., et al. B cells as a therapeutic target for IFN-{beta} in relapsing-remitting multiple sclerosis. J. Immunol. 2011, 186:4518-4526.
    • (2011) J. Immunol. , vol.186 , pp. 4518-4526
    • Ramgolam, V.S.1
  • 82
    • 77954041785 scopus 로고    scopus 로고
    • Interferon-beta inhibits Th17 cell differentiation in patients with multiple sclerosis
    • Ramgolam V.S., Markovic-Plese S. Interferon-beta inhibits Th17 cell differentiation in patients with multiple sclerosis. Endocr. Metab. Immune Disord. Drug Targets 2010, 10:161-167.
    • (2010) Endocr. Metab. Immune Disord. Drug Targets , vol.10 , pp. 161-167
    • Ramgolam, V.S.1    Markovic-Plese, S.2
  • 83
    • 77950534540 scopus 로고    scopus 로고
    • T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis
    • Axtell R.C., et al. T helper type 1 and 17 cells determine efficacy of interferon-beta in multiple sclerosis and experimental encephalomyelitis. Nat. Med. 2010, 16:406-412.
    • (2010) Nat. Med. , vol.16 , pp. 406-412
    • Axtell, R.C.1
  • 84
    • 37549011317 scopus 로고    scopus 로고
    • Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses
    • Zaba L.C., et al. Amelioration of epidermal hyperplasia by TNF inhibition is associated with reduced Th17 responses. J. Exp. Med. 2007, 204:3183-3194.
    • (2007) J. Exp. Med. , vol.204 , pp. 3183-3194
    • Zaba, L.C.1
  • 85
    • 77958072084 scopus 로고    scopus 로고
    • Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis
    • Hueber W., et al. Effects of AIN457, a fully human antibody to interleukin-17A, on psoriasis, rheumatoid arthritis, and uveitis. Sci. Transl. Med. 2010, 2:52ra72.
    • (2010) Sci. Transl. Med. , vol.2
    • Hueber, W.1
  • 86
    • 77950535421 scopus 로고    scopus 로고
    • LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study
    • Genovese M.C., et al. LY2439821, a humanized anti-interleukin-17 monoclonal antibody, in the treatment of patients with rheumatoid arthritis: A phase I randomized, double-blind, placebo-controlled, proof-of-concept study. Arthritis Rheum. 2010, 62:929-939.
    • (2010) Arthritis Rheum. , vol.62 , pp. 929-939
    • Genovese, M.C.1
  • 87
    • 33748286452 scopus 로고    scopus 로고
    • The role of interleukin-17 during acute rejection after lung transplantation
    • Vanaudenaerde B.M., et al. The role of interleukin-17 during acute rejection after lung transplantation. Eur. Respir. J. 2006, 27:779-787.
    • (2006) Eur. Respir. J. , vol.27 , pp. 779-787
    • Vanaudenaerde, B.M.1
  • 88
    • 36048968753 scopus 로고    scopus 로고
    • IL-17-dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants
    • Burlingham W.J., et al. IL-17-dependent cellular immunity to collagen type V predisposes to obliterative bronchiolitis in human lung transplants. J. Clin. Invest. 2007, 117:3498-3506.
    • (2007) J. Clin. Invest. , vol.117 , pp. 3498-3506
    • Burlingham, W.J.1
  • 89
    • 73349094069 scopus 로고    scopus 로고
    • Role of T cell TGFbeta signaling and IL-17 in allograft acceptance and fibrosis associated with chronic rejection
    • Faust S.M., et al. Role of T cell TGFbeta signaling and IL-17 in allograft acceptance and fibrosis associated with chronic rejection. J. Immunol. 2009, 183:7297-7306.
    • (2009) J. Immunol. , vol.183 , pp. 7297-7306
    • Faust, S.M.1
  • 90
    • 68349144297 scopus 로고    scopus 로고
    • Changes in the serum levels of interleukin-17/interleukin-23 during acute rejection in liver transplantation
    • Fabrega E., et al. Changes in the serum levels of interleukin-17/interleukin-23 during acute rejection in liver transplantation. Liver Transpl. 2009, 15:629-633.
    • (2009) Liver Transpl. , vol.15 , pp. 629-633
    • Fabrega, E.1
  • 91
    • 77954467012 scopus 로고    scopus 로고
    • Intragraft Th17 infiltrate promotes lymphoid neogenesis and hastens clinical chronic rejection
    • Deteix C., et al. Intragraft Th17 infiltrate promotes lymphoid neogenesis and hastens clinical chronic rejection. J. Immunol. 2010, 184:5344-5351.
    • (2010) J. Immunol. , vol.184 , pp. 5344-5351
    • Deteix, C.1
  • 92
    • 0041474807 scopus 로고    scopus 로고
    • Activation-induced cytidine deaminase: a dual role in class-switch recombination and somatic hypermutation
    • Durandy A. Activation-induced cytidine deaminase: a dual role in class-switch recombination and somatic hypermutation. Eur. J. Immunol. 2003, 33:2069-2073.
    • (2003) Eur. J. Immunol. , vol.33 , pp. 2069-2073
    • Durandy, A.1
  • 93
    • 79551541633 scopus 로고    scopus 로고
    • T helper 1, 2 and 17 cell subsets in renal transplant patients with delayed graft function
    • Loverre A., et al. T helper 1, 2 and 17 cell subsets in renal transplant patients with delayed graft function. Transpl. Int. 2011, 24:233-242.
    • (2011) Transpl. Int. , vol.24 , pp. 233-242
    • Loverre, A.1
  • 94
    • 79953312645 scopus 로고    scopus 로고
    • Dynamic changes in Th1, Th17, and FoxP3(+) T cells in patients with acute cellular rejection after cardiac transplantation
    • Wang S., et al. Dynamic changes in Th1, Th17, and FoxP3(+) T cells in patients with acute cellular rejection after cardiac transplantation. Clin. Transplant. 2010, 25:E177-E186.
    • (2010) Clin. Transplant. , vol.25
    • Wang, S.1
  • 95
    • 73349105621 scopus 로고    scopus 로고
    • Interleukin-17-producing T-helper cells as new potential player mediating graft-versus-host disease in patients undergoing allogeneic stem-cell transplantation
    • Dander E., et al. Interleukin-17-producing T-helper cells as new potential player mediating graft-versus-host disease in patients undergoing allogeneic stem-cell transplantation. Transplantation 2009, 88:1261-1272.
    • (2009) Transplantation , vol.88 , pp. 1261-1272
    • Dander, E.1
  • 96
    • 77958545437 scopus 로고    scopus 로고
    • Interleukin-17-producing cells increase among CD4+ lymphocytes before overt manifestation of acute graft-versus-host disease
    • Dlubek D., et al. Interleukin-17-producing cells increase among CD4+ lymphocytes before overt manifestation of acute graft-versus-host disease. Transplant. Proc. 2010, 42:3277-3279.
    • (2010) Transplant. Proc. , vol.42 , pp. 3277-3279
    • Dlubek, D.1
  • 97
    • 78149464264 scopus 로고    scopus 로고
    • Prognostic significance of genetic variants in the IL-23/Th17 pathway for the outcome of T cell-depleted allogeneic stem cell transplantation
    • Carvalho A., et al. Prognostic significance of genetic variants in the IL-23/Th17 pathway for the outcome of T cell-depleted allogeneic stem cell transplantation. Bone Marrow Transplant. 2010, 45:1645-1652.
    • (2010) Bone Marrow Transplant. , vol.45 , pp. 1645-1652
    • Carvalho, A.1
  • 98
    • 75149118145 scopus 로고    scopus 로고
    • T helper17 cells are sufficient but not necessary to induce acute graft-versus-host disease
    • Iclozan C., et al. T helper17 cells are sufficient but not necessary to induce acute graft-versus-host disease. Biol. Blood Marrow Transplant. 2010, 16:170-178.
    • (2010) Biol. Blood Marrow Transplant. , vol.16 , pp. 170-178
    • Iclozan, C.1
  • 99
    • 52049087356 scopus 로고    scopus 로고
    • Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease
    • Anderson G.P. Endotyping asthma: new insights into key pathogenic mechanisms in a complex, heterogeneous disease. Lancet 2008, 372:1107-1119.
    • (2008) Lancet , vol.372 , pp. 1107-1119
    • Anderson, G.P.1
  • 100
    • 79959937269 scopus 로고    scopus 로고
    • Th17 cells: new players in asthma pathogenesis
    • Cosmi L., et al. Th17 cells: new players in asthma pathogenesis. Allergy 2011, 66:989-998.
    • (2011) Allergy , vol.66 , pp. 989-998
    • Cosmi, L.1
  • 101
    • 0033557728 scopus 로고    scopus 로고
    • Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways
    • Laan M., et al. Neutrophil recruitment by human IL-17 via C-X-C chemokine release in the airways. J. Immunol. 1999, 162:2347-2352.
    • (1999) J. Immunol. , vol.162 , pp. 2347-2352
    • Laan, M.1
  • 102
    • 0037216818 scopus 로고    scopus 로고
    • Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma
    • Hellings P.W., et al. Interleukin-17 orchestrates the granulocyte influx into airways after allergen inhalation in a mouse model of allergic asthma. Am. J. Respir. Cell Mol. Biol. 2003, 28:42-50.
    • (2003) Am. J. Respir. Cell Mol. Biol. , vol.28 , pp. 42-50
    • Hellings, P.W.1
  • 103
    • 77951165107 scopus 로고    scopus 로고
    • Interleukin-17A activation on bronchial epithelium and basophils: a novel inflammatory mechanism
    • Wong C.K., et al. Interleukin-17A activation on bronchial epithelium and basophils: a novel inflammatory mechanism. Eur. Respir. J. 2010, 35:883-893.
    • (2010) Eur. Respir. J. , vol.35 , pp. 883-893
    • Wong, C.K.1
  • 104
    • 77957962666 scopus 로고    scopus 로고
    • Interleukin-17A promotes IgE production in human B cells
    • Milovanovic M., et al. Interleukin-17A promotes IgE production in human B cells. J. Invest. Dermatol. 2010, 130:2621-2628.
    • (2010) J. Invest. Dermatol. , vol.130 , pp. 2621-2628
    • Milovanovic, M.1
  • 105
    • 0242720198 scopus 로고    scopus 로고
    • Allergy and hypersensitivity. Nature versus nurture in allergy and hypersensitivity
    • Geha R.S. Allergy and hypersensitivity. Nature versus nurture in allergy and hypersensitivity. Curr. Opin. Immunol. 2003, 15:603-608.
    • (2003) Curr. Opin. Immunol. , vol.15 , pp. 603-608
    • Geha, R.S.1
  • 106
    • 77955350723 scopus 로고    scopus 로고
    • Induction of glucocorticoid receptor-beta expression in epithelial cells of asthmatic airways by T-helper type 17 cytokines
    • Vazquez-Tello A., et al. Induction of glucocorticoid receptor-beta expression in epithelial cells of asthmatic airways by T-helper type 17 cytokines. Clin. Exp. Allergy 2010, 40:1312-1322.
    • (2010) Clin. Exp. Allergy , vol.40 , pp. 1312-1322
    • Vazquez-Tello, A.1
  • 107
    • 0029056558 scopus 로고
    • Glucocorticoid receptor beta, a potential endogenous inhibitor of glucocorticoid action in humans
    • Bamberger C.M., et al. Glucocorticoid receptor beta, a potential endogenous inhibitor of glucocorticoid action in humans. J. Clin. Invest. 1995, 95:2435-2441.
    • (1995) J. Clin. Invest. , vol.95 , pp. 2435-2441
    • Bamberger, C.M.1
  • 108
    • 70350041508 scopus 로고    scopus 로고
    • Th17 immunity in patients with allergic asthma
    • Zhao Y., et al. Th17 immunity in patients with allergic asthma. Int. Arch. Allergy Immunol. 2010, 151:297-307.
    • (2010) Int. Arch. Allergy Immunol. , vol.151 , pp. 297-307
    • Zhao, Y.1
  • 109
    • 0037636682 scopus 로고    scopus 로고
    • Interleukin-17 in sputum correlates with airway hyperresponsiveness to methacholine
    • Barczyk A., et al. Interleukin-17 in sputum correlates with airway hyperresponsiveness to methacholine. Respir. Med. 2003, 97:726-733.
    • (2003) Respir. Med. , vol.97 , pp. 726-733
    • Barczyk, A.1
  • 110
    • 67349203306 scopus 로고    scopus 로고
    • T(H)17-associated cytokines (IL-17A and IL-17F) in severe asthma
    • Al-Ramli W., et al. T(H)17-associated cytokines (IL-17A and IL-17F) in severe asthma. J. Allergy Clin. Immunol. 2009, 123:1185-1187.
    • (2009) J. Allergy Clin. Immunol. , vol.123 , pp. 1185-1187
    • Al-Ramli, W.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.