-
1
-
-
2142662186
-
Multiple sclerosis
-
Hafler, D.A. (2004) Multiple sclerosis. J. Clin. Invest., 113, 788-794.
-
(2004)
J. Clin. Invest
, vol.113
, pp. 788-794
-
-
Hafler, D.A.1
-
2
-
-
17644396349
-
Immunology of multiple sclerosis
-
Sospedra, M. and Martin, R. (2005) Immunology of multiple sclerosis. Annu. Rev. Immunol., 23, 683-747.
-
(2005)
Annu. Rev. Immunol
, vol.23
, pp. 683-747
-
-
Sospedra, M.1
Martin, R.2
-
4
-
-
0037228871
-
Molecular tracking of antigen-specific T cell clones in neurological immune-mediated disorders
-
Muraro, P.A.; Wandinger K.P.; Bielekova B.; Gran, B.; Marques, A.; Utz, U.; McFarland, H.F.; Jacobson, S. and Martin, R. (2003) Molecular tracking of antigen-specific T cell clones in neurological immune-mediated disorders. Brain, 126, 20-31.
-
(2003)
Brain
, vol.126
, pp. 20-31
-
-
Muraro, P.A.1
Wandinger, K.P.2
Bielekova, B.3
Gran, B.4
Marques, A.5
Utz, U.6
McFarland, H.F.7
Jacobson, S.8
Martin, R.9
-
5
-
-
0027418515
-
Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I: Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. The IFNB Multiple Sclerosis Study Group
-
The IFNb Multiple Sclerosis Study Group
-
The IFNb Multiple Sclerosis Study Group. (1993) Interferon beta-1b is effective in relapsing-remitting multiple sclerosis. I: Clinical results of a multicenter, randomized, double-blind, placebo-controlled trial. The IFNB Multiple Sclerosis Study Group. Neurology, 43, 655-661.
-
(1993)
Neurology
, vol.43
, pp. 655-661
-
-
-
6
-
-
0345601517
-
Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis
-
PRISMS (Prevention of Relapses and Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) Study Group. Study Group
-
PRISMS (Prevention of Relapses and Disability by Interferon beta-1a Subcutaneously in Multiple Sclerosis) Study Group. Study Group. (1998) Randomised double-blind placebo-controlled study of interferon beta-1a in relapsing/remitting multiple sclerosis. Lancet, 352, 1498-1504.
-
(1998)
Lancet
, vol.352
, pp. 1498-1504
-
-
-
7
-
-
0008678962
-
Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis
-
and The Multiple Sclerosis Collaborative (MSCRG) Research Group
-
Jacobs, L.D.; Cookfair, D.L.; Rudick, R.A.; Herndon, R.M.; Richert, J.R.; Salazar, A.M.; Fischer, J.S.; Goodkin, D.E.; Granger, C.V.; Simon, J.H.; Alam, J.J.; Bartoszak, D.M.; Bourdette, D.N.; Braiman, J.; Brownscheidle, C.M.; Coats, M.E.; Cohan, S.L.; Dougherty, D.S.; Kinkel, R.P.; Mass, M.K.; Munschauer, F.E.; Priore, R.L.; Pullicino, P.M.; Scherokman, B.J.; Whitham, R.H. and The Multiple Sclerosis Collaborative (MSCRG) Research Group. (1996) Intramuscular interferon beta-1a for disease progression in relapsing multiple sclerosis. Ann. Neurol., 39, 285-294.
-
(1996)
Ann. Neurol
, vol.39
, pp. 285-294
-
-
Jacobs, L.D.1
Cookfair, D.L.2
Rudick, R.A.3
Herndon, R.M.4
Richert, J.R.5
Salazar, A.M.6
Fischer, J.S.7
Goodkin, D.E.8
Granger, C.V.9
Simon, J.H.10
Alam, J.J.11
Bartoszak, D.M.12
Bourdette, D.N.13
Braiman, J.14
Brownscheidle, C.M.15
Coats, M.E.16
Cohan, S.L.17
Dougherty, D.S.18
Kinkel, R.P.19
Mass, M.K.20
Munschauer, F.E.21
Priore, R.L.22
Pullicino, P.M.23
Scherokman, B.J.24
Whitham, R.H.25
more..
-
8
-
-
0034727059
-
Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis. CHAMPS Study Group
-
Jacobs, L.D.; Beck, R.W.; Simon, J.H.; Kinkel, R.P.; Brown-scheidle, C.M.; Murray, T.J.; Simonian, N.A.; Slasor, P.J. and Sandrock, A.W. (2000). Intramuscular interferon beta-1a therapy initiated during a first demyelinating event in multiple sclerosis. CHAMPS Study Group. N. Engl. J. Med., 343, 898-904.
-
(2000)
N. Engl. J. Med
, vol.343
, pp. 898-904
-
-
Jacobs, L.D.1
Beck, R.W.2
Simon, J.H.3
Kinkel, R.P.4
Brown-Scheidle, C.M.5
Murray, T.J.6
Simonian, N.A.7
Slasor, P.J.8
Sandrock, A.W.9
-
9
-
-
33749661011
-
Treatment with interferon beta-1b delays conversion to clinically definite and McDonald MS in patients with clinically isolated syndromes
-
Kappos, L.; Polman, C.H.; Freedman, M.S.; Edan, G.; Hartung, H.P.; Miller, D.H.; Montalban, X.; Barkhof, F.; Bauer, L.; Jakobs, P.; Pohl, C. and Sandbrink, R. (2006) Treatment with interferon beta-1b delays conversion to clinically definite and McDonald MS in patients with clinically isolated syndromes. Neurology, 67, 1242-1249.
-
(2006)
Neurology
, vol.67
, pp. 1242-1249
-
-
Kappos, L.1
Polman, C.H.2
Freedman, M.S.3
Edan, G.4
Hartung, H.P.5
Miller, D.H.6
Montalban, X.7
Barkhof, F.8
Bauer, L.9
Jakobs, P.10
Pohl, C.11
Sandbrink, R.12
-
10
-
-
0035912520
-
Effect of early interferon treatment on conversion to definite multiple sclerosis: A randomised study
-
Comi, G.; Filippi, M.; Barkhof, F.; Durelli, L.; Edan, G.; Fernandez, O.; Hartung, H.; Seeldrayers, P.; Sorensen, P.S.; Rovaris, M.; Martinelli, V. and Hommes, O.R. (2001) Effect of early interferon treatment on conversion to definite multiple sclerosis: a randomised study. Lancet, 357, 1576-1582.
-
(2001)
Lancet
, vol.357
, pp. 1576-1582
-
-
Comi, G.1
Filippi, M.2
Barkhof, F.3
Durelli, L.4
Edan, G.5
Fernandez, O.6
Hartung, H.7
Seeldrayers, P.8
Sorensen, P.S.9
Rovaris, M.10
Martinelli, V.11
Hommes, O.R.12
-
11
-
-
0030953511
-
Diminished production of type-I interferons and interleukin-2 in patients with multiple sclerosis
-
Wandinger, K.P.; Wessel, K.; Neustock, P.; Siekhaus, A. and Kirchner, H. (1997) Diminished production of type-I interferons and interleukin-2 in patients with multiple sclerosis. J. Neurol. Sci., 149, 87-93.
-
(1997)
J. Neurol. Sci
, vol.149
, pp. 87-93
-
-
Wandinger, K.P.1
Wessel, K.2
Neustock, P.3
Siekhaus, A.4
Kirchner, H.5
-
12
-
-
0031947747
-
Production of endogenous interferon-alpha and beta in patients with multiple sclerosis
-
Wandinger, K.P.; Reissland, P.; Kirchner, H.; Wessel, K. and Otto, M. (1998) Production of endogenous interferon-alpha and beta in patients with multiple sclerosis. J. Neurol. Neurosurg. Psychiatry, 64, 277-278.
-
(1998)
J. Neurol. Neurosurg. Psychiatry
, vol.64
, pp. 277-278
-
-
Wandinger, K.P.1
Reissland, P.2
Kirchner, H.3
Wessel, K.4
Otto, M.5
-
13
-
-
43049101640
-
The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice
-
Guo, B.; Chang, E.Y. and Cheng, G. (2008) The type I IFN induction pathway constrains Th17-mediated autoimmune inflammation in mice. J. Clin. Invest., 118, 1680-1690.
-
(2008)
J. Clin. Invest
, vol.118
, pp. 1680-1690
-
-
Guo, B.1
Chang, E.Y.2
Cheng, G.3
-
14
-
-
0037407587
-
IFN-beta gene deletion leads to augmented and chronic demyelinating experimental autoimmune encephalomyelitis
-
Teige, I.; Treschow, A.; Teige, A.; Mattsson, R.; Navikas, V.; Leanderson, T.; Holmdahl, R. and Issazadeh-Navikas, S. (2003) IFN-beta gene deletion leads to augmented and chronic demyelinating experimental autoimmune encephalomyelitis. J. Immunol., 170, 4776-4784.
-
(2003)
J. Immunol
, vol.170
, pp. 4776-4784
-
-
Teige, I.1
Treschow, A.2
Teige, A.3
Mattsson, R.4
Navikas, V.5
Leanderson, T.6
Holmdahl, R.7
Issazadeh-Navikas, S.8
-
15
-
-
43049177588
-
Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system
-
Prinz, M.; Schmidt, H.; Mildner, A.; Knobeloch, K.P.; Hanisch, U.K.; Raasch, J.; Merkler, D.; Detje, C.; Gutcher, I.; Mages, J.; Lang, R.; Martin, R.; Gold, R.; Becher, B.; Brück, W. and Kalinke, U. (2008) Distinct and nonredundant in vivo functions of IFNAR on myeloid cells limit autoimmunity in the central nervous system. Immunity, 28, 675-686.
-
(2008)
Immunity
, vol.28
, pp. 675-686
-
-
Prinz, M.1
Schmidt, H.2
Mildner, A.3
Knobeloch, K.P.4
Hanisch, U.K.5
Raasch, J.6
Merkler, D.7
Detje, C.8
Gutcher, I.9
Mages, J.10
Lang, R.11
Martin, R.12
Gold, R.13
Becher, B.14
Brück, W.15
Kalinke, U.16
-
16
-
-
44449146212
-
Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: Role of intracellular osteopontin
-
Shinohara, M.l.; Kim, J.H.; Garcia, V.A. and Cantor. H. (2008) Engagement of the type I interferon receptor on dendritic cells inhibits T helper 17 cell development: role of intracellular osteopontin. Immunity, 29, 68-78.
-
(2008)
Immunity
, vol.29
, pp. 68-78
-
-
Shinohara, M.L.1
Kim, J.H.2
Garcia, V.A.3
-
17
-
-
0038692013
-
Expression profiling identifies responder and non-responder phenotypes to interferon-beta in multiple sclerosis
-
Sturzebecher, S.; Wandinger, K.P.; Rosenwald, A.; Sathyamoorthy, M.; Tzou, A.; Mattar, P.; Frank, J.A.; Staudt, L.; Martin, R. and McFarland, H.F. (2003) Expression profiling identifies responder and non-responder phenotypes to interferon-beta in multiple sclerosis. Brain, 126, 1419-1429.
-
(2003)
Brain
, vol.126
, pp. 1419-1429
-
-
Sturzebecher, S.1
Wandinger, K.P.2
Rosenwald, A.3
Sathyamoorthy, M.4
Tzou, A.5
Mattar, P.6
Frank, J.A.7
Staudt, L.8
Martin, R.9
McFarland, H.F.10
-
18
-
-
0030773332
-
Characterization of MRI response to treatment with interferon beta-1b: Contrast-enhancing MRI lesion frequency as a primary outcome measure
-
Stone, L.A.; Frank, J.A.; Albert, P.S.; Bash, C.N.; Calabresi, P.A.; Maloni, H. and McFarland, H.F. (1997) Characterization of MRI response to treatment with interferon beta-1b: contrast-enhancing MRI lesion frequency as a primary outcome measure. Neurology, 49, 862-869.
-
(1997)
Neurology
, vol.49
, pp. 862-869
-
-
Stone, L.A.1
Frank, J.A.2
Albert, P.S.3
Bash, C.N.4
Calabresi, P.A.5
Maloni, H.6
McFarland, H.F.7
-
19
-
-
0036789860
-
Assessment of different treatment failure criteria in a cohort of relapsing-remitting multiple sclerosis patients treated with interferon beta: Implications for clinical trials
-
Rio, J.; Nos, C.; Tintore, M.; Borras, C.; Galan, I.; Comabella, M. and Montalban, X. (2002) Assessment of different treatment failure criteria in a cohort of relapsing-remitting multiple sclerosis patients treated with interferon beta: implications for clinical trials. Ann. Neurol., 52, 400-406.
-
(2002)
Ann. Neurol
, vol.52
, pp. 400-406
-
-
Rio, J.1
Nos, C.2
Tintore, M.3
Borras, C.4
Galan, I.5
Comabella, M.6
Montalban, X.7
-
20
-
-
4844223606
-
Defining interferon beta response status in multiple sclerosis patients
-
Rudick, R.A.; Lee, J.C.; Simon, J.; Ransohoff, R.M. and Fisher, E. (2004) Defining interferon beta response status in multiple sclerosis patients. Ann. Neurol., 56, 548-555.
-
(2004)
Ann. Neurol
, vol.56
, pp. 548-555
-
-
Rudick, R.A.1
Lee, J.C.2
Simon, J.3
Ransohoff, R.M.4
Fisher, E.5
-
21
-
-
44849128066
-
Pharmacogenomics of interferon-beta therapy in multiple sclerosis: Baseline IFN signature determines pharmacological differences between patients
-
] Van Baarsen, L.G.; Vosslamber, S.; Tijssen, M.; Baggen, J.M.; Van Der Voort, L.F.; Killestein, J.; Van Der Pouw Kraan, T.C.; Polman, C.G. and Verweij, C.L. (2008) Pharmacogenomics of interferon-beta therapy in multiple sclerosis: baseline IFN signature determines pharmacological differences between patients. PLoS One, 3, E1927.
-
(2008)
PLoS One
, vol.3
-
-
van Baarsen, L.G.1
Vosslamber, S.2
Tijssen, M.3
Baggen, J.M.4
van der Voort, L.F.5
Killestein, J.6
van der Pouw Kraan, T.C.7
Polman, C.G.8
Verweij, C.L.9
-
22
-
-
12444304354
-
TNF-related apoptosis inducing ligand (TRAIL) as a potential response marker for interferon-beta treatment in multiple sclerosis
-
Wandinger, K.P.; Lunemann, J.D.; Wengert, O.; Bellmann-Strobl, J.; Aktas, O.; Weber, A.; Grundstrom, E.; Ehrlich, S.; Wernecke, K.D.; Volk, H.D. and Zipp, F. (2003) TNF-related apoptosis inducing ligand (TRAIL) as a potential response marker for interferon-beta treatment in multiple sclerosis. Lancet, 361, 2036-2043.
-
(2003)
Lancet
, vol.361
, pp. 2036-2043
-
-
Wandinger, K.P.1
Lunemann, J.D.2
Wengert, O.3
Bellmann-Strobl, J.4
Aktas, O.5
Weber, A.6
Grundstrom, E.7
Ehrlich, S.8
Wernecke, K.D.9
Volk, H.D.10
Zipp, F.11
-
23
-
-
72649106903
-
A type I interferon signature in monocytes is associated with poor response to interferon-beta in multiple sclerosis
-
Comabella, M.; Lunemann, J.D.; Rio, J.; Sanchez, A.; Lopez, C.; Julia, E.; Fernandez, M.; Nonell, L.; Camina-Tato, M.; Deisenhammer, F.; Caballero, E.; Tortola, M.T.; Prinz, M.; Montalban, X. and Martin, R. (2009) A type I interferon signature in monocytes is associated with poor response to interferon-beta in multiple sclerosis. Brain, 132, 3353-3365.
-
(2009)
Brain
, vol.132
, pp. 3353-3365
-
-
Comabella, M.1
Lunemann, J.D.2
Rio, J.3
Sanchez, A.4
Lopez, C.5
Julia, E.6
Fernandez, M.7
Nonell, L.8
Camina-Tato, M.9
Deisenhammer, F.10
Caballero, E.11
Tortola, M.T.12
Prinz, M.13
Montalban, X.14
Martin, R.15
-
24
-
-
0036154417
-
Interferon-beta therapy for multiple sclerosis induces reciprocal changes in interleukin-12 and interleukin-10 production
-
Byrnes, A.A.; Mcarthur, J.C. and Karp, C.L. (2002) Interferon-beta therapy for multiple sclerosis induces reciprocal changes in interleukin-12 and interleukin-10 production. Ann. Neurol., 51, 165-174.
-
(2002)
Ann. Neurol
, vol.51
, pp. 165-174
-
-
Byrnes, A.A.1
McArthur, J.C.2
Karp, C.L.3
-
25
-
-
0034855936
-
Complex immunomodulatory effects of interferon-beta in multiple sclerosis include the upregulation of T helper 1-associated marker genes
-
Wandinger, K.P.; Sturzebecher, C.S.; Bielekova, B.; Detore, G.; Rosenwald, A.; Staudt, L.M.; McFarland, H.F. and Martin, R. (2001) Complex immunomodulatory effects of interferon-beta in multiple sclerosis include the upregulation of T helper 1-associated marker genes. Ann. Neurol., 50, 349-57.
-
(2001)
Ann. Neurol
, vol.50
, pp. 349-357
-
-
Wandinger, K.P.1
Sturzebecher, C.S.2
Bielekova, B.3
Detore, G.4
Rosenwald, A.5
Staudt, L.M.6
McFarland, H.F.7
Martin, R.8
-
26
-
-
27544490377
-
Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages
-
Harrington, L.E.; Hatton, R.D.; Mangan, P.R.; Turner, H.; Murphy, T.L.; Murphy, K.M. and Weaver, C.T. (2005) Interleukin 17-producing CD4+ effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages. Nat. Immunol., 6,1123-1132.
-
(2005)
Nat. Immunol
, vol.6
, pp. 1123-1132
-
-
Harrington, L.E.1
Hatton, R.D.2
Mangan, P.R.3
Turner, H.4
Murphy, T.L.5
Murphy, K.M.6
Weaver, C.T.7
-
27
-
-
33747588291
-
Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells
-
Batten, M.; Li, J.; Yi, S.; Kljavin, N.M.; Danilenko, D.M.; Lucas, S.; Lee, J.; De Sauvage, F.J. and Ghilardi, N. (2006) Interleukin 27 limits autoimmune encephalomyelitis by suppressing the development of interleukin 17-producing T cells. Nat. Immunol., 7, 929-936.
-
(2006)
Nat. Immunol
, vol.7
, pp. 929-936
-
-
Batten, M.1
Li, J.2
Yi, S.3
Kljavin, N.M.4
Danilenko, D.M.5
Lucas, S.6
Lee, J.7
de Sauvage, F.J.8
Ghilardi, N.9
-
28
-
-
34548125305
-
Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells
-
Acosta-Rodriguez, E.V.; Napolitani, G.; Lanzavecchia, A. and Sallusto, F. (2007) Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells. Nat. Immunol., 8, 942-949.
-
(2007)
Nat. Immunol
, vol.8
, pp. 942-949
-
-
Acosta-Rodriguez, E.V.1
Napolitani, G.2
Lanzavecchia, A.3
Sallusto, F.4
-
29
-
-
34548133583
-
Development, cytokine profile and function of human interleukin 17-producing helper T cells
-
Wilson, N.J.; Boniface, K.; Chan, J.R.; Mckenzie, B.S.; Blumenschein, W.M.; Mattson, J.D.; Basham, B.; Smith, K.; Chen, T.; Morel, F.; Lecron, J.C.; Kastelein, R.A.; Cua, D.J.; Mcclanaha, T.K.; Bowman, E.P. and De Waal Malefyt, R. (2007) Development, cytokine profile and function of human interleukin 17-producing helper T cells. Nat. Immunol., 8, 950-957.
-
(2007)
Nat. Immunol
, vol.8
, pp. 950-957
-
-
Wilson, N.J.1
Boniface, K.2
Chan, J.R.3
McKenzie, B.S.4
Blumenschein, W.M.5
Mattson, J.D.6
Basham, B.7
Smith, K.8
Chen, T.9
Morel, F.10
Lecron, J.C.11
Kastelein, R.A.12
Cua, D.J.13
McClanaha, T.K.14
Bowman, E.P.15
de Waal Malefyt, R.16
-
30
-
-
34547734621
-
Phenotypic and functional features of human Th-17 cells
-
Annunziato, F.; Cosmi, L.; Santarlasci, V.; Maggi, L.; Liotta, F.; Mazzinghi, B.; Parente, E.; Fili, L.; Ferri, S.; Frosali, F.; Giudici, F.; Romagnani, P.; Parronchi, P.; Tonelli, F.; Maggi, E. and Romagnani S. (2007) Phenotypic and functional features of human Th-17 cells. J. Exp. Med., 204, 1849-1861.
-
(2007)
J. Exp. Med
, vol.204
, pp. 1849-1861
-
-
Annunziato, F.1
Cosmi, L.2
Santarlasci, V.3
Maggi, L.4
Liotta, F.5
Mazzinghi, B.6
Parente, E.7
Fili, L.8
Ferri, S.9
Frosali, F.10
Giudici, F.11
Romagnani, P.12
Parronchi, P.13
Tonelli, F.14
Maggi, E.15
Romagnani, S.16
-
31
-
-
47549112840
-
IL-21 and TGF-beta are required for differentiation of human T(H)17 cells
-
Yang, L.; Anderson, D.E.; Baecher-Allan, C.; Hastings, W.D.; Bettelli, E.; Oukka, M.; Kuchroo, V.K. and Hafler, D.A. (2008) IL-21 and TGF-beta are required for differentiation of human T(H)17 cells. Nature, 454, 350-352.
-
(2008)
Nature
, vol.454
, pp. 350-352
-
-
Yang, L.1
Anderson, D.E.2
Baecher-Allan, C.3
Hastings, W.D.4
Bettelli, E.5
Oukka, M.6
Kuchroo, V.K.7
Hafler, D.A.8
-
32
-
-
44049102724
-
-
Volpe, E.; Servant, N.; Zollinger, R.; Bogiatzi, S.I.; Hupé, P.; Barillot, E. and Soumelis, V. (2008) Nat. Immunol., 9, 650-657.
-
(2008)
Nat. Immunol
, vol.9
, pp. 650-657
-
-
Volpe, E.1
Servant, N.2
Zollinger, R.3
Bogiatzi, S.I.4
Hupé, P.5
Barillot, E.6
Soumelis, V.7
-
33
-
-
44049104564
-
The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat
-
Manel, N.; Unutmaz, D. and. Littman, D.R. (2008) The differentiation of human T(H)-17 cells requires transforming growth factor-beta and induction of the nuclear receptor RORgammat. Nat. Immunol., 9, 641-649.
-
(2008)
Nat. Immunol
, vol.9
, pp. 641-649
-
-
Manel, N.1
Unutmaz, D.2
Littman, D.R.3
-
34
-
-
34249079176
-
Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells
-
Acosta-Rodriguez, E.V.; Rivino, L.; Geginat, J.; Jarrossay, D.; Gattorno, M.; Lanzavecchia, A.; Sallusto, F. and Napolitani, G. (2007) Surface phenotype and antigenic specificity of human interleukin 17-producing T helper memory cells. Nat. Immunol., 8, 639-646.
-
(2007)
Nat. Immunol
, vol.8
, pp. 639-646
-
-
Acosta-Rodriguez, E.V.1
Rivino, L.2
Geginat, J.3
Jarrossay, D.4
Gattorno, M.5
Lanzavecchia, A.6
Sallusto, F.7
Napolitani, G.8
-
35
-
-
58149251898
-
Late developmental plasticity in the T helper 17 lineage
-
Lee, Y.K.; Turner, H.; Maynard, C.L.; Oliver, J.R.; Chen, D.; Elson, C.O. and Weaver, C.T. (2009) Late developmental plasticity in the T helper 17 lineage. Immunity, 30, 92-107.
-
(2009)
Immunity
, vol.30
, pp. 92-107
-
-
Lee, Y.K.1
Turner, H.2
Maynard, C.L.3
Oliver, J.R.4
Chen, D.5
Elson, C.O.6
Weaver, C.T.7
-
36
-
-
42249114634
-
The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease
-
Carlson, T.; Kroenke, M.; Rao, P.; Lane, T.E. and Segal, B. (2008) The Th17-ELR+ CXC chemokine pathway is essential for the development of central nervous system autoimmune disease. J. Exp. Med., 205, 811-823.
-
(2008)
J. Exp. Med
, vol.205
, pp. 811-823
-
-
Carlson, T.1
Kroenke, M.2
Rao, P.3
Lane, T.E.4
Segal, B.5
-
37
-
-
0033134608
-
IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis
-
Kotake, S.; Udagawa, N.; Takahashi, N.; Matsuzaki, K.; Itoh, K.; Ishiyama, S.; Saito, S.; Inoue, K.; Kamatani, N.; Gillespie, M.T.; Martin, T.J. and Suda, T. (1999) IL-17 in synovial fluids from patients with rheumatoid arthritis is a potent stimulator of osteoclastogenesis. J. Clin. Invest., 103, 1345-1352.
-
(1999)
J. Clin. Invest
, vol.103
, pp. 1345-1352
-
-
Kotake, S.1
Udagawa, N.2
Takahashi, N.3
Matsuzaki, K.4
Itoh, K.5
Ishiyama, S.6
Saito, S.7
Inoue, K.8
Kamatani, N.9
Gillespie, M.T.10
Martin, T.J.11
Suda, T.12
-
38
-
-
37349131221
-
Pathophysiology of psoriasis: Recent advances on IL-23 and Th17 cytokines
-
Fitch, E.; Harper, E.; Skorcheva, I.; Kurtz, S.E. and Blauvelt, A. (2007) Pathophysiology of psoriasis: recent advances on IL-23 and Th17 cytokines. Curr. Rheumatol. Rep., 9, 461-467.
-
(2007)
Curr. Rheumatol. Rep
, vol.9
, pp. 461-467
-
-
Fitch, E.1
Harper, E.2
Skorcheva, I.3
Kurtz, S.E.4
Blauvelt, A.5
-
39
-
-
34250005444
-
Th-17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT-1
-
Amadi-Obi, A.; Yu, C.R.; Liu, X.; Mahdi, R.M.; Clarke, G.L.; Nussenblatt, R.B.; Gery, I.; Lee, Y.S. and Egwuagu, C.E. (2007) Th-17 cells contribute to uveitis and scleritis and are expanded by IL-2 and inhibited by IL-27/STAT-1. Nat. Med., 13, 711-718.
-
(2007)
Nat. Med
, vol.13
, pp. 711-718
-
-
Amadi-Obi, A.1
Yu, C.R.2
Liu, X.3
Mahdi, R.M.4
Clarke, G.L.5
Nussenblatt, R.B.6
Gery, I.7
Lee, Y.S.8
Egwuagu, C.E.9
-
40
-
-
0344389016
-
Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis
-
Matusevicius, D.; Kivisakk, P.; He, B.; Kostulas, N.; Ozenci, V.; Fredrikson, S. and Link, H. (1999). Interleukin-17 mRNA expression in blood and CSF mononuclear cells is augmented in multiple sclerosis. Mult. Scler., 5, 101-104.
-
(1999)
Mult. Scler
, vol.5
, pp. 101-104
-
-
Matusevicius, D.1
Kivisakk, P.2
He, B.3
Kostulas, N.4
Ozenci, V.5
Fredrikson, S.6
Link, H.7
-
41
-
-
67249090787
-
T-helper 17 cells expand in multiple sclerosis and are inhibited by interferon-beta
-
Durelli, L.; Conti, L.; Clerico, M.; Boselli, D.; Contessa, G.; Ripellino, P.; Ferrero, B.; Eid, P. and Novelli, F. (2009) T-helper 17 cells expand in multiple sclerosis and are inhibited by interferon-beta. Ann. Neurol., 65, 499-509.
-
(2009)
Ann. Neurol
, vol.65
, pp. 499-509
-
-
Durelli, L.1
Conti, L.2
Clerico, M.3
Boselli, D.4
Contessa, G.5
Ripellino, P.6
Ferrero, B.7
Eid, P.8
Novelli, F.9
-
42
-
-
0036105484
-
Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis
-
Lock, C.; Hermans, G.; Pedotti, R.; Brendolan, A.; Schadt, E.; Garren, H.; Langer-Gould, A.; Strober, S.; Cannella, B.; Allard, J.; Klonowski, P.; Austin, A.; Lad, N.; Kaminski, N.; Galli, S.J.; Oksenberg, J.R.; Raine, C.S.; Heller, R. and Steinman, L. (2002) Gene-microarray analysis of multiple sclerosis lesions yields new targets validated in autoimmune encephalomyelitis. Nat. Med., 8, 451-453.
-
(2002)
Nat. Med
, vol.8
, pp. 451-453
-
-
Lock, C.1
Hermans, G.2
Pedotti, R.3
Brendolan, A.4
Schadt, E.5
Garren, H.6
Langer-Gould, A.7
Strober, S.8
Cannella, B.9
Allard, J.10
Klonowski, P.11
Austin, A.12
Lad, N.13
Kaminski, N.14
Galli, S.J.15
Oksenberg, J.R.16
Raine, C.S.17
Heller, R.18
Steinman, L.19
-
43
-
-
38749143286
-
Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis
-
Tzartos, J.S.; Friese, M.A.; Craner, M.J.; Palace, J.; Newcombe, J.; Esiri, M. M. and Fugger, L. (2008) Interleukin-17 production in central nervous system-infiltrating T cells and glial cells is associated with active disease in multiple sclerosis. Am. J. Pathol., 172, 146-55.
-
(2008)
Am. J. Pathol
, vol.172
, pp. 146-155
-
-
Tzartos, J.S.1
Friese, M.A.2
Craner, M.J.3
Palace, J.4
Newcombe, J.5
Esiri, M.M.6
Fugger, L.7
-
44
-
-
47049114045
-
Degenerate TCR recognition and dual DR2 restriction in auto-reactive T-cells: Implications for the initiation of the autoimmune response in multiple sclerosis
-
Zhang, X.; Tang, Y.; Sujkowska, D.; Wang, J.; Ramgolam, V.S.; Sospedra, M.; Adams, J.; Martin, R.; Pinilla, C. and Markovic-Plese, S. (2008) Degenerate TCR recognition and dual DR2 restriction in auto-reactive T-cells: implications for the initiation of the autoimmune response in multiple sclerosis Eur. J. Immunol., 38, 1297-1309.
-
(2008)
Eur. J. Immunol
, vol.38
, pp. 1297-1309
-
-
Zhang, X.1
Tang, Y.2
Sujkowska, D.3
Wang, J.4
Ramgolam, V.S.5
Sospedra, M.6
Adams, J.7
Martin, R.8
Pinilla, C.9
Markovic-Plese, S.10
-
45
-
-
0030067819
-
A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes
-
Devergne, O.; Hummel, M.; Koeppen, H.; Le Beau, M.M.; Nathanson, E.C.; Kieff, E. and Birkenbach, M. (1996) A novel interleukin-12 p40-related protein induced by latent Epstein-Barr virus infection in B lymphocytes. J. Virol., 70, 1143-1153.
-
(1996)
J. Virol
, vol.70
, pp. 1143-1153
-
-
Devergne, O.1
Hummel, M.2
Koeppen, H.3
Le Beau, M.M.4
Nathanson, E.C.5
Kieff, E.6
Birkenbach, M.7
-
46
-
-
18444385868
-
IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells
-
Pflanz, S.; Timans, J.C.; Cheung, J.; Rosales, R.; Kanzler, H.; Gilbert, J.; Hibbert, L.; Churakova, T.; Travis, M.; Vaisberg, E.; Blumenschein, W.M.; Mattson, J.D.; Wagner, J.l.; To, W.; Zurawski, S.; McClanahan, T.K.; Gorman, D.M.; Bazan, J.F.; de Waal Malefyt, R.; Rennick, D. and Kastelein, R.A. (2002) IL-27, a heterodimeric cytokine composed of EBI3 and p28 protein, induces proliferation of naive CD4(+) T cells. Immunity, 16, 779-790.
-
(2002)
Immunity
, vol.16
, pp. 779-790
-
-
Pflanz, S.1
Timans, J.C.2
Cheung, J.3
Rosales, R.4
Kanzler, H.5
Gilbert, J.6
Hibbert, L.7
Churakova, T.8
Travis, M.9
Vaisberg, E.10
Blumenschein, W.M.11
Mattson, J.D.12
Wagner, J.L.13
To, W.14
Zurawski, S.15
McClanahan, T.K.16
Gorman, D.M.17
Bazan, J.F.18
de Waal Malefyt, R.19
Rennick, D.20
Kastelein, R.A.21
more..
-
47
-
-
10744222574
-
WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27
-
Pflanz, S.; Hibbert, L.; Mattson, J.; Rosales, R.; Vaisberg, E.; Bazan, J.F.; Phillips, J.H., McClanahan, T.K.; De Waal Malefyt, R. and Kastelein, R.A. (2004) WSX-1 and glycoprotein 130 constitute a signal-transducing receptor for IL-27. J. Immunol., 172, 2225-2231.
-
(2004)
J. Immunol
, vol.172
, pp. 2225-2231
-
-
Pflanz, S.1
Hibbert, L.2
Mattson, J.3
Rosales, R.4
Vaisberg, E.5
Bazan, J.F.6
Phillips, J.H.7
McClanahan, T.K.8
de Waal Malefyt, R.9
Kastelein, R.A.10
-
48
-
-
77950526192
-
IFN-beta inhibits human Th17 cell differentiation
-
Ramgolam, V.S.; Sha, Y.; Jin, J.; Zhang, X. and Markovic-Plese, S, (2009) IFN-beta inhibits human Th17 cell differentiation. J. Immunol., 183, 5418-5427.
-
(2009)
J. Immunol
, vol.183
, pp. 5418-5427
-
-
Ramgolam, V.S.1
Sha, Y.2
Jin, J.3
Zhang, X.4
Markovic-Plese, S.5
-
49
-
-
0036604306
-
A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R
-
Parham, C.; Chirica, M.; Timans, J.; Vaisberg, E.; Travis, M.; Cheung, J.; Pflanz, S.; Zhang, R.; Singh, K.P.; Vega, F.; To, W.; Wagner, J.; O'Farell, A.M.; McClanahan, T.; Zurawski, S.; Hannum, C.; Gorman, D.; Rennick, D.M.; Kastelein, R.A.; de Waal Malefyt, R. and Moore, K.W. (2002) A receptor for the heterodimeric cytokine IL-23 is composed of IL-12Rbeta1 and a novel cytokine receptor subunit, IL-23R. J. Immunol., 168, 5699-5708.
-
(2002)
J. Immunol
, vol.168
, pp. 5699-5708
-
-
Parham, C.1
Chirica, M.2
Timans, J.3
Vaisberg, E.4
Travis, M.5
Cheung, J.6
Pflanz, S.7
Zhang, R.8
Singh, K.P.9
Vega, F.10
To, W.11
Wagner, J.12
O'Farell, A.M.13
McClanahan, T.14
Zurawski, S.15
Hannum, C.16
Gorman, D.17
Rennick, D.M.18
Kastelein, R.A.19
de Waal Malefyt, R.20
Moore, K.W.21
more..
-
50
-
-
33646433989
-
Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis
-
Chen, Y.; Langrish, C.L.; Mckenzie, B.; Joyce-Shaikh, B.; Stumhofer, J.S.; Mcclanahan, T.; Blumenschein, W.; Churakovsa, T.; Low, J.; Presta, L.; Hunter, C.A.; Kastelein, R.A. and Cua, J.D. (2006) Anti-IL-23 therapy inhibits multiple inflammatory pathways and ameliorates autoimmune encephalomyelitis. J. Clin. Invest., 116, 1317-1326.
-
(2006)
J. Clin. Invest
, vol.116
, pp. 1317-1326
-
-
Chen, Y.1
Langrish, C.L.2
McKenzie, B.3
Joyce-Shaikh, B.4
Stumhofer, J.S.5
McClanahan, T.6
Blumenschein, W.7
Churakovsa, T.8
Low, J.9
Presta, L.10
Hunter, C.A.11
Kastelein, R.A.12
Cua, J.D.13
-
51
-
-
0037434789
-
Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain
-
Cua, D.J.; Sherlock, J.; Chen, Y.; Murphy, C.A.; Joyce, B.; Seymour, B.; Lucian, L.; To, W.; Kwan, S.; Churakova, T.; Zurawski, S.; Wiekowski, M.; Lira, S.A.; Gorman, D.; Kastelein, R.A. and Sedgwick, J.D. (2003) Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain. Nature, 421, 744-748.
-
(2003)
Nature
, vol.421
, pp. 744-748
-
-
Cua, D.J.1
Sherlock, J.2
Chen, Y.3
Murphy, C.A.4
Joyce, B.5
Seymour, B.6
Lucian, L.7
To, W.8
Kwan, S.9
Churakova, T.10
Zurawski, S.11
Wiekowski, M.12
Lira, S.A.13
Gorman, D.14
Kastelein, R.A.15
Sedgwick, J.D.16
-
52
-
-
10744230574
-
Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-beta 2-deficient mice:12-responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system
-
Zhang, G.X.; Yu, S.; Gran, B.; Li, J.; Siglienti, I.; Chen, X.; Calida, D.; Ventura, E.; Kamoun, M. and Rostami, A. (2003) Induction of experimental autoimmune encephalomyelitis in IL-12 receptor-beta 2-deficient mice:12-responsiveness is not required in the pathogenesis of inflammatory demyelination in the central nervous system. J. Immunol., 171, 4485-4492.
-
(2003)
J. Immunol
, vol.171
, pp. 4485-4492
-
-
Zhang, G.X.1
Yu, S.2
Gran, B.3
Li, J.4
Siglienti, I.5
Chen, X.6
Calida, D.7
Ventura, E.8
Kamoun, M.9
Rostami, A.10
-
53
-
-
18644364701
-
A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells
-
Gautier, G.; Humbert, M.; Deavieau, F.; Scuiller, M.; Hiscott, J.; Bates, E.E.; Trinchieri, G.; Caux, G. and Garrone, P. (2005) A type I interferon autocrine-paracrine loop is involved in Toll-like receptor-induced interleukin-12p70 secretion by dendritic cells. J. Exp. Med., 201, 1435-1446.
-
(2005)
J. Exp. Med
, vol.201
, pp. 1435-1446
-
-
Gautier, G.1
Humbert, M.2
Deavieau, F.3
Scuiller, M.4
Hiscott, J.5
Bates, E.E.6
Trinchieri, G.7
Caux, G.8
Garrone, P.9
-
54
-
-
34848821989
-
Distinct regulation of interleukin-17 in human T helper lymphocytes
-
Chen, Z.; Tato, C.M.; Muul, L.; Laurence, A. and O'Shea, J.J. (2007) Distinct regulation of interleukin-17 in human T helper lymphocytes. Arthritis Rheum., 56, 2936-2946.
-
(2007)
Arthritis Rheum
, vol.56
, pp. 2936-2946
-
-
Chen, Z.1
Tato, C.M.2
Muul, L.3
Laurence, A.4
O'Shea, J.J.5
-
55
-
-
77449112013
-
Regulating human Th17 cells via differential expression of IL-1 receptor
-
Lee, W.W.; Kang, S.W.; Choi, J.; Lee, S.H.; Shah, K.; Eynon, E.E.; Flavell, R.A. and Kang I. (2009) Regulating human Th17 cells via differential expression of IL-1 receptor. Blood, 115, 530-540.
-
(2009)
Blood
, vol.115
, pp. 530-540
-
-
Lee, W.W.1
Kang, S.W.2
Choi, J.3
Lee, S.H.4
Shah, K.5
Eynon, E.E.6
Flavell, R.A.7
Kang, I.8
-
56
-
-
33744936550
-
IL-23 is increased in dendritic cells in multiple scelerosis and downregulation of IL-23 by antisense oligos increases dendritic cell IL-10 production
-
Vaknin-Dembinsky A.; Balashov, K. and Weiner, H.L. (2006) IL-23 is increased in dendritic cells in multiple scelerosis and downregulation of IL-23 by antisense oligos increases dendritic cell IL-10 production. J. Immunol., 176, 7768-7774.
-
(2006)
J. Immunol
, vol.176
, pp. 7768-7774
-
-
Vaknin-Dembinsky, A.1
Balashov, K.2
Weiner, H.L.3
-
57
-
-
33846593869
-
Increased IL-23p19 expression in multiple sclerosis lesions and its induction in microglia
-
Li, Y.; Chu, N.; Hu, A.; Gran, B.; Rostami, A. and Zhang, G.X. (2007) Increased IL-23p19 expression in multiple sclerosis lesions and its induction in microglia. Brain, 130, 490-501.
-
(2007)
Brain
, vol.130
, pp. 490-501
-
-
Li, Y.1
Chu, N.2
Hu, A.3
Gran, B.4
Rostami, A.5
Zhang, G.X.6
-
58
-
-
65449177629
-
IFN-beta1a inhibits the secretion of Th17-polarizing cytokines in human dendritic cells via TLR7 up-regulation
-
Zhang, X.; Jin, J.; Tang, Y.; Speer, D.; Sujkowska, D. and Markovic-Plese, S. (2009) IFN-beta1a inhibits the secretion of Th17-polarizing cytokines in human dendritic cells via TLR7 up-regulation. J. Immunol., 182, 3928-3936.
-
(2009)
J. Immunol
, vol.182
, pp. 3928-3936
-
-
Zhang, X.1
Jin, J.2
Tang, Y.3
Speer, D.4
Sujkowska, D.5
Markovic-Plese, S.6
-
59
-
-
46849101948
-
Increased IL-10 mRNA and IL-23 mRNA expression in multiple sclerosis: Interferon-beta treatment increases IL-10 mRNA expression while reducing IL-23 mRNA expression
-
Krakauer, M.; Sorensen, P.; Khademi, M.; Olsson, T. and Sellebjerg, F. (2008) Increased IL-10 mRNA and IL-23 mRNA expression in multiple sclerosis: interferon-beta treatment increases IL-10 mRNA expression while reducing IL-23 mRNA expression. Mult. Scler., 14, 622-630.
-
(2008)
Mult. Scler
, vol.14
, pp. 622-630
-
-
Krakauer, M.1
Sorensen, P.2
Khademi, M.3
Olsson, T.4
Sellebjerg, F.5
-
60
-
-
0031463988
-
Interferon-beta not only inhibits interleukin-1beta and tumor necrosis factor-alpha but stimulates interleukin-1 receptor antagonist production in human peripheral blood mononuclear cells
-
Coclet-Ninin, J.; Dayer, J.M. and Burger, D. (1997) Interferon-beta not only inhibits interleukin-1beta and tumor necrosis factor-alpha but stimulates interleukin-1 receptor antagonist production in human peripheral blood mononuclear cells. Eur. Cytokine. Netw., 8, 345-349.
-
(1997)
Eur. Cytokine. Netw
, vol.8
, pp. 345-349
-
-
Coclet-Ninin, J.1
Dayer, J.M.2
Burger, D.3
-
61
-
-
33745190069
-
SOCS-3 negatively regulates innate and adaptive immune mechanisms in acute IL-1-dependent inflammatory arthritis
-
Wong, P.K.; Croker, B.A.; O'donnell, K.; Sims, N.A.; Drake, S.; Kiu, H.; Mcmanus, E.J.; Alexander, W.S.; Roberts, A.W. and Wicks, I.P. (2006) SOCS-3 negatively regulates innate and adaptive immune mechanisms in acute IL-1-dependent inflammatory arthritis. J. Clin. Invest., 116, 1571-1581.
-
(2006)
J. Clin. Invest
, vol.116
, pp. 1571-1581
-
-
Wong, P.K.1
Croker, B.A.2
O'Donnell, K.3
Sims, N.A.4
Drake, S.5
Kiu, H.6
McManus, E.J.7
Alexander, W.S.8
Roberts, A.W.9
Wicks, I.P.10
-
62
-
-
33745194935
-
Suppressor of cytokine signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex
-
Frobose, H.; Ronn, S.G.; Heding, P.E.; Mendoza, H.; Cohen, P.; Mandrup-Poulsen, T. and Billestrup, N. (2006) Suppressor of cytokine signaling-3 inhibits interleukin-1 signaling by targeting the TRAF-6/TAK1 complex. Mol. Endocrinol., 20, 1587-1596.
-
(2006)
Mol. Endocrinol
, vol.20
, pp. 1587-1596
-
-
Frobose, H.1
Ronn, S.G.2
Heding, P.E.3
Mendoza, H.4
Cohen, P.5
Mandrup-Poulsen, T.6
Billestrup, N.7
-
63
-
-
33746190828
-
Dendritic cells transduced with SOCS-3 exhibit a tolerogenic/DC2 phenotype that directs type 2 Th cell differentiation in vitro and in vivo. J
-
Li, Y.; Chu, N.; Rostami, A. and Zhang, G.X. (2006) Dendritic cells transduced with SOCS-3 exhibit a tolerogenic/DC2 phenotype that directs type 2 Th cell differentiation in vitro and in vivo. J. Immunol., 177, 1679-1688.
-
(2006)
Immunol
, vol.177
, pp. 1679-1688
-
-
Li, Y.1
Chu, N.2
Rostami, A.3
Zhang, G.X.4
-
64
-
-
45549102525
-
Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORc in CD4+ lymphocytes
-
Zhang, X.; Jin, J.; Peng, X.; Ramgolam, V.S. and Markovic-Plese, S. (2008) Simvastatin inhibits IL-17 secretion by targeting multiple IL-17-regulatory cytokines and by inhibiting the expression of IL-17 transcription factor RORc in CD4+ lymphocytes. J. Immunol., 180, 6988-6996.
-
(2008)
J. Immunol
, vol.180
, pp. 6988-6996
-
-
Zhang, X.1
Jin, J.2
Peng, X.3
Ramgolam, V.S.4
Markovic-Plese, S.5
-
65
-
-
44849115688
-
Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-gamma on STAT3 and Smads
-
Tanaka, K.; Ichiyama, K.; Hashimoto, M.; Yoshida, H.; Takimoto, T.; Takaesu, G.; Torisu, T.; Hanada, T.; Yasukawa, H.; Fukuyama, S.; Inoue, H.; Nakanishi, Y.; Kobayashi, T. and Yoshimura, A. (2008) Loss of suppressor of cytokine signaling 1 in helper T cells leads to defective Th17 differentiation by enhancing antagonistic effects of IFN-gamma on STAT3 and Smads. J. Immunol., 180, 3746-3756.
-
(2008)
J. Immunol
, vol.180
, pp. 3746-3756
-
-
Tanaka, K.1
Ichiyama, K.2
Hashimoto, M.3
Yoshida, H.4
Takimoto, T.5
Takaesu, G.6
Torisu, T.7
Hanada, T.8
Yasukawa, H.9
Fukuyama, S.10
Inoue, H.11
Nakanishi, Y.12
Kobayashi, T.13
Yoshimura, A.14
-
66
-
-
46949089128
-
Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3
-
Ma, C,S.; Chew, Gy.; Simpson, N.; Priyadarshi, A.; Wong, M.; Grimbacher, B.; Fulcher, D.A.; Tangye, S.G. and Cook, M.C. (2008) Deficiency of Th17 cells in hyper IgE syndrome due to mutations in STAT3. J. Exp. Med., 205, 1551-1557.
-
(2008)
J. Exp. Med
, vol.205
, pp. 1551-1557
-
-
Ma, C.S.1
Chew, G.2
Simpson, N.3
Priyadarshi, A.4
Wong, M.5
Grimbacher, B.6
Fulcher, D.A.7
Tangye, S.G.8
Cook, M.C.9
-
67
-
-
66949157620
-
IL-27 blocks RORc expression to inhibit lineage commitment of Th17 cells
-
Diveu, C.; Mcgeachy, M.J.; Boniface, K.; Stumhofer, J.S.; Sathe, M.; Joyce-Shaikh, B.; Chen, Y.; Tato, C.M.; McClanahan, T.K.; De Waal Malefyt, R.; Hunter, C.A.; Cua, D.J. and Kastelein, R.A. (2009) IL-27 blocks RORc expression to inhibit lineage commitment of Th17 cells. J. Immunol., 182, 5748-5756.
-
(2009)
J. Immunol
, vol.182
, pp. 5748-5756
-
-
Diveu, C.1
McGeachy, M.J.2
Boniface, K.3
Stumhofer, J.S.4
Sathe, M.5
Joyce-Shaikh, B.6
Chen, Y.7
Tato, C.M.8
McClanahan, T.K.9
de Waal Malefyt, R.10
Hunter, C.A.11
Cua, D.J.12
Kastelein, R.A.13
-
68
-
-
33744479688
-
Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells
-
Chen, Z.; Laurence, A.; Kanno, Y.; Pacher-Zavisin, M.; Zhu, B.M.; Tato, C.; Yoshimura, A.; Hennighausen, L. and O'Shea, J.J. (2006)Selective regulatory function of Socs3 in the formation of IL-17-secreting T cells. Proc. Natl. Acad. Sci. USA, 103, 8137-8142.
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 8137-8142
-
-
Chen, Z.1
Laurence, A.2
Kanno, Y.3
Pacher-Zavisin, M.4
Zhu, B.M.5
Tato, C.6
Yoshimura, A.7
Hennighausen, L.8
O'Shea, J.J.9
-
69
-
-
0032975730
-
Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis
-
Van Boxel-Dezaire, A.H.; Hoff, S.C.; Van Oosten, B.W.; Verweij, C.l.; Drager, A.M.; Ader, H.J.; Van Houwelingen, J.C.; Barkhof, F.; Polman, C.H. and Nagelkerken, L. (1999) Decreased interleukin-10 and increased interleukin-12p40 mRNA are associated with disease activity and characterize different disease stages in multiple sclerosis. Ann. Neurol., 45, 695-703.
-
(1999)
Ann. Neurol
, vol.45
, pp. 695-703
-
-
Van Boxel-Dezaire, A.H.1
Hoff, S.C.2
van Oosten, B.W.3
Verweij, C.L.4
Drager, A.M.5
Ader, H.J.6
van Houwelingen, J.C.7
Barkhof, F.8
Polman, C.H.9
Nagelkerken, L.10
-
70
-
-
33748791731
-
The interleukin-10 levels as a potential indicator of positive response to interferon beta treatment of multiple sclerosis patients
-
Bartosik-Psujek, H. and Stelmasiak, Z. (2006) The interleukin-10 levels as a potential indicator of positive response to interferon beta treatment of multiple sclerosis patients. Clin. Neurol. Neurosurg., 108, 644-647.
-
(2006)
Clin. Neurol. Neurosurg
, vol.108
, pp. 644-647
-
-
Bartosik-Psujek, H.1
Stelmasiak, Z.2
-
71
-
-
0032977543
-
Multiple sclerosis: Levels of interleukin-10-secreting blood mononuclear cells are low in untreated patients but augmented during interferon-beta-1b treatment
-
Ozenci, V.; Kouwenhoven, M.; Huang, Y.M.; Xiao, B.; Kivisakk, P.; Fredrikson, S. and Link, H. (1999) Multiple sclerosis: levels of interleukin-10-secreting blood mononuclear cells are low in untreated patients but augmented during interferon-beta-1b treatment. Scand. J. Immunol., 49, 554-561.
-
(1999)
Scand. J. Immunol
, vol.49
, pp. 554-561
-
-
Ozenci, V.1
Kouwenhoven, M.2
Huang, Y.M.3
Xiao, B.4
Kivisakk, P.5
Fredrikson, S.6
Link, H.7
-
72
-
-
54949141219
-
Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression
-
Matsushita, T.; Yanaba, K.; Bouaziz, J.D.; Fujimoto, M. and Tedder, T.F. (2008) Regulatory B cells inhibit EAE initiation in mice while other B cells promote disease progression. J. Clin. Invest., 118, 3420-3430.
-
(2008)
J. Clin. Invest
, vol.118
, pp. 3420-3430
-
-
Matsushita, T.1
Yanaba, K.2
Bouaziz, J.D.3
Fujimoto, M.4
Tedder, T.F.5
-
73
-
-
35648988381
-
Suppressive effect of IL-27 on encephalitogenic Th17 cells and the effector phase of experimental autoimmune encephalomyelitis
-
Fitzgerald, D.C, Ciric, B.; Touil, T.; Harle, H.; Grammatikopolou, J.; Das Sarma, J.; Gran, B.; Zhang, G.X. and Rostami, A. (2007) Suppressive effect of IL-27 on encephalitogenic Th17 cells and the effector phase of experimental autoimmune encephalomyelitis. J. Immunol., 179, 3268-3275.
-
(2007)
J. Immunol
, vol.179
, pp. 3268-3275
-
-
Fitzgerald, D.C.1
Ciric, B.2
Touil, T.3
Harle, H.4
Grammatikopolou, J.5
Das Sarma, J.6
Gran, B.7
Zhang, G.X.8
Rostami, A.9
-
74
-
-
36248951161
-
Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10
-
Stumhofer, J.S.; Silver, J.S.; Laurence, A.; Porrett, P.M.; Turka, T.H.; Ernst, M.;.Saris, S.J.; O'Shea, J.J. and Hunter, C.A. (2007) Interleukins 27 and 6 induce STAT3-mediated T cell production of interleukin 10. Nat. Immunol., 8, 1363-1371.
-
Nat. Immunol
, vol.8
, pp. 1363-1371
-
-
Stumhofer, J.S.1
Silver, J.S.2
Laurence, A.3
Porrett, P.M.4
Turka, T.H.5
Ernst, M.6
Saris, S.J.7
O'Shea, J.J.8
Hunter, C.A.9
-
75
-
-
17444374245
-
Upon TLR9 signaling, CD5+ B cells control the IL-12-dependent Th1-priming capacity of neonatal DCs
-
Sun, C.M.; Deriaud, E.; Leclerc, C. and Lo-Man, R. (2005) Upon TLR9 signaling, CD5+ B cells control the IL-12-dependent Th1-priming capacity of neonatal DCs. Immunity, 22, 467-477.
-
(2005)
Immunity
, vol.22
, pp. 467-477
-
-
Sun, C.M.1
Deriaud, E.2
Leclerc, C.3
Lo-Man, R.4
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