Th17 cells promote pancreatic inflammation but only induce diabetes efficiently in lymphopenic hosts after conversion into Th1 cells

European Journal of Immunology

Volumn 39, Issue 1, 2009, Pages 216-224

  Martin Orozco, Natalia ^a   Chung, Yeonseok ^a   Chang, Seon Hee ^a   Wang, Yi Hong ^a   Dong, Chen ^a  

^a UNIVERSITY OF TEXAS MD ANDERSON CANCER CENTER   (United States)

Author keywords

Islet inflammation; Th17; Type 1 diabetes

Indexed keywords

CD4 ANTIGEN; GAMMA INTERFERON; INTERLEUKIN 17; T LYMPHOCYTE RECEPTOR;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; CYTOKINE PRODUCTION; DIABETOGENESIS; DISEASE COURSE; HELPER CELL; IMMUNOPATHOGENESIS; IN VITRO STUDY; INSULIN DEPENDENT DIABETES MELLITUS; INSULITIS; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE FUNCTION; LYMPHOCYTOPENIA; MOUSE; NEWBORN; NONHUMAN; PANCREATITIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; TH1 CELL; TH17 CELL; ANIMAL; BIOSYNTHESIS; CELL DIFFERENTIATION; IMMUNOLOGY; NONOBESE DIABETIC MOUSE; PANCREAS ISLET BETA CELL; PATHOLOGY; T LYMPHOCYTE SUBPOPULATION;

ANIMALS; CELL DIFFERENTIATION; DIABETES MELLITUS, TYPE 1; INSULIN-SECRETING CELLS; INTERFERON-GAMMA; INTERLEUKIN-17; LYMPHOPENIA; MICE; MICE, INBRED NOD; PANCREATITIS; T-LYMPHOCYTE SUBSETS; T-LYMPHOCYTES, HELPER-INDUCER; TH1 CELLS;

EID: 60549086638     PISSN: 00142980     EISSN: 15214141     Source Type: Journal    
DOI: 10.1002/eji.200838475     Document Type: Article

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