-
2
-
-
0015361994
-
The formation and stabilization of protein structure
-
Anfinsen, C. (1972). The formation and stabilization of protein structure. Biochemistry Journal, 128, 737-749.
-
(1972)
Biochemistry Journal
, vol.128
, pp. 737-749
-
-
Anfinsen, C.1
-
3
-
-
34547499110
-
The design and characterization of two proteins with 88% sequence identity but different structure and function
-
Alexander, P. A., He, Y., Chen, Y., Orban, J., & Bryan, P. N. (2007). The design and characterization of two proteins with 88% sequence identity but different structure and function. Proceedings of the National Academy of Scences of the United States of America, 104, 11963-11968.
-
(2007)
Proceedings of the National Academy of Scences of the United States of America
, vol.104
, pp. 11963-11968
-
-
Alexander, P.A.1
He, Y.2
Chen, Y.3
Orban, J.4
Bryan, P.N.5
-
4
-
-
0028235775
-
Molecular mechanisms of acid denaturation The role of histidine residues in the partial unfolding of apomyoglobin
-
Barrick, D., Hughson, F. M., & Baldwin, R. L. (1994). Molecular mechanisms of acid denaturation The role of histidine residues in the partial unfolding of apomyoglobin. Journal of Molecular Biology, 237, 588-601.
-
(1994)
Journal of Molecular Biology
, vol.237
, pp. 588-601
-
-
Barrick, D.1
Hughson, F.M.2
Baldwin, R.L.3
-
5
-
-
0025876740
-
Protein folding: Local structure, domains, subunits, and assemblies
-
Jaenicke, R. (1991). Protein folding: Local structure, domains, subunits, and assemblies. Biochemistry, 30, 3147-3161.
-
(1991)
Biochemistry
, vol.30
, pp. 3147-3161
-
-
Jaenicke, R.1
-
6
-
-
18844438057
-
Partially folded intermediate state of concanavalin A retains its carbohydrate specificity
-
Naeem, A., Khan, A., & Khan, R. H. (2005). Partially folded intermediate state of concanavalin A retains its carbohydrate specificity. Biochemistry and Biophysics Research Communications, 331, 1284-1294.
-
(2005)
Biochemistry and Biophysics Research Communications
, vol.331
, pp. 1284-1294
-
-
Naeem, A.1
Khan, A.2
Khan, R.H.3
-
7
-
-
0027391299
-
Characterization of an intermediate in the folding pathway of phosphoglycerate kinase: Chemical reactivity of genetically introduced cysteinyl residues during the folding process
-
Ballery, N., Desmadril, M., Minard, P., & Yon, J. M. (1993). Characterization of an intermediate in the folding pathway of phosphoglycerate kinase: Chemical reactivity of genetically introduced cysteinyl residues during the folding process. Biochemistry, 32, 708-714.
-
(1993)
Biochemistry
, vol.32
, pp. 708-714
-
-
Ballery, N.1
Desmadril, M.2
Minard, P.3
Yon, J.M.4
-
8
-
-
0026524680
-
The folding of an enzyme IV Structure of an intermediate in the refolding of barnase analyzed by a protein engineering procedure
-
Matousschek, A., Serrano, L., Meiering, E. M., Bycroft, M., & Ferscht, A. R. (1992). The folding of an enzyme IV Structure of an intermediate in the refolding of barnase analyzed by a protein engineering procedure. Journal of Molecular Biology, 224, 837-845.
-
(1992)
Journal of Molecular Biology
, vol.224
, pp. 837-845
-
-
Matousschek, A.1
Serrano, L.2
Meiering, E.M.3
Bycroft, M.4
Ferscht, A.R.5
-
9
-
-
7044228278
-
Characterization of a partially folded intermediate of papain induced by fluorinated alcohols at low pH
-
Naeem, A., Khan, K. A., & Khan, R. H. (2004). Characterization of a partially folded intermediate of papain induced by fluorinated alcohols at low pH. Archives of Biochemistry and Biophysics, 432, 79-87.
-
(2004)
Archives of Biochemistry and Biophysics
, vol.432
, pp. 79-87
-
-
Naeem, A.1
Khan, K.A.2
Khan, R.H.3
-
10
-
-
0026351184
-
Role of electrostatic repulsion in the acidic molten globule of cytochrome c
-
Goto, Y., & Nishikiori, S. J. (1991). Role of electrostatic repulsion in the acidic molten globule of cytochrome c. Journal of Molecular Biology, 222, 679-686.
-
(1991)
Journal of Molecular Biology
, vol.222
, pp. 679-686
-
-
Goto, Y.1
Nishikiori, S.J.2
-
11
-
-
78650420370
-
A partially folded state of ovalbumin at low pH tends to aggregate
-
Naeem, A., Ahmad, T., Muzaffar, M., Ahmad, S., & Saleemuddin, M. (2011). A partially folded state of ovalbumin at low pH tends to aggregate. Cell Biochemistry and Biophysics, 59, 29-38.
-
(2011)
Cell Biochemistry and Biophysics
, vol.59
, pp. 29-38
-
-
Naeem, A.1
Ahmad, T.2
Muzaffar, M.3
Ahmad, S.4
Saleemuddin, M.5
-
12
-
-
0023655983
-
Conformational changes induced in lens alpha-and gamma crystallins by modification with glucose 6-phosphate Implications for cataract
-
Beswick, H. T., & Harding, J. J. (1987). Conformational changes induced in lens alpha-and gamma crystallins by modification with glucose 6-phosphate Implications for cataract. Biochemistry Journal, 246, 761-769.
-
(1987)
Biochemistry Journal
, vol.246
, pp. 761-769
-
-
Beswick, H.T.1
Harding, J.J.2
-
13
-
-
0028272883
-
Pathogenic effects of advanced glycosylation: Biochemical, biologic, and clinical implications for diabetes and aging
-
Vlassara, H., Bucala, R., & Striker, L. (1994). Pathogenic effects of advanced glycosylation: Biochemical, biologic, and clinical implications for diabetes and aging. Laboratory Investigation, 70, 138-151.
-
(1994)
Laboratory Investigation
, vol.70
, pp. 138-151
-
-
Vlassara, H.1
Bucala, R.2
Striker, L.3
-
14
-
-
0021782568
-
Non enzymatic covalent post translational modification of proteins in vivo
-
Harding, J. J. (1985). Non enzymatic covalent post translational modification of proteins in vivo. Advances in Protein Chemistry, 37, 247-334.
-
(1985)
Advances in Protein Chemistry
, vol.37
, pp. 247-334
-
-
Harding, J.J.1
-
16
-
-
0032489016
-
The Hsp70 and Hsp60 chaperone machines
-
Bukau, B., & Horwich, A. L. (1998). The Hsp70 and Hsp60 chaperone machines. Cell, 92, 351-366.
-
(1998)
Cell
, vol.92
, pp. 351-366
-
-
Bukau, B.1
Horwich, A.L.2
-
17
-
-
0037040541
-
Molecular chaperones in the cytosol: From nascent chain to folded protein
-
Hartl, F. U., & Hayer-Hartl, M. (2002). Molecular chaperones in the cytosol: From nascent chain to folded protein. Science, 295, 1852-1858.
-
(2002)
Science
, vol.295
, pp. 1852-1858
-
-
Hartl, F.U.1
Hayer-Hartl, M.2
-
19
-
-
0347357617
-
Protein folding and misfolding
-
Dobson, C. M. (2003). Protein folding and misfolding. Nature, 426, 884-890.
-
(2003)
Nature
, vol.426
, pp. 884-890
-
-
Dobson, C.M.1
-
20
-
-
33750945327
-
A backbone-based theory of protein folding
-
Rose, G., Fleming, P., Banavar, J., & Maritan, A. (2006). A backbone-based theory of protein folding. Proceedings of the National Academy of Sciences of the United States of America, 103, 166231-166233.
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, pp. 166231-166233
-
-
Rose, G.1
Fleming, P.2
Banavar, J.3
Maritan, A.4
-
21
-
-
0029124248
-
Molten globule and protein folding
-
Ptitsyn, O. B. (1995). Molten globule and protein folding. Advances in Protein Chemistry, 47, 83-87.
-
(1995)
Advances in Protein Chemistry
, vol.47
, pp. 83-87
-
-
Ptitsyn, O.B.1
-
23
-
-
0037264120
-
Unfolding the role of protein misfolding in neurodegenerative diseases
-
Soto, C. (2003). Unfolding the role of protein misfolding in neurodegenerative diseases. Nature Reviews Neuroscience, 4, 49-60.
-
(2003)
Nature Reviews Neuroscience
, vol.4
, pp. 49-60
-
-
Soto, C.1
-
24
-
-
0037159944
-
Determination of the structures of distinct transition state ensembles for a β-sheet peptide with parallel folding pathways
-
Davis, R., Dobson, C. M., & Vendruscolo, M. (2002). Determination of the structures of distinct transition state ensembles for a β-sheet peptide with parallel folding pathways. Journal of Chemical Physics, 117, 9510-9517.
-
(2002)
Journal of Chemical Physics
, vol.117
, pp. 9510-9517
-
-
Davis, R.1
Dobson, C.M.2
Vendruscolo, M.3
-
25
-
-
0026059137
-
Peptide-binding specificity of the molecular chaperone BiP
-
Flynn, G. C., Pohl, J., Flocco, MT., & Rothman, J. E. (1991). Peptide-binding specificity of the molecular chaperone BiP. Nature, 353, 726-730.
-
(1991)
Nature
, vol.353
, pp. 726-730
-
-
Flynn, G.C.1
Pohl, J.2
Flocco, M.T.3
Rothman, J.E.4
-
26
-
-
0026595140
-
Different conformations for the same polypeptide bound to chaperones DnaK and GroEL
-
Landry, S. J., Jordan, R., McMacken, R., & Gierasch, L. M. (1992). Different conformations for the same polypeptide bound to chaperones DnaK and GroEL. Nature, 355, 455-457.
-
(1992)
Nature
, vol.355
, pp. 455-457
-
-
Landry, S.J.1
Jordan, R.2
McMacken, R.3
Gierasch, L.M.4
-
27
-
-
0026584271
-
Protein folding in the cell
-
Gething, M. J., & Sambrook, J. (1992). Protein folding in the cell. Nature, 355, 33-45.
-
(1992)
Nature
, vol.355
, pp. 33-45
-
-
Gething, M.J.1
Sambrook, J.2
-
28
-
-
0026773208
-
Protein folding in the cell: The role of molecular chaperones Hsp70 and Hsp60
-
Harti, F. U., Martin, J., & Neupert, W. (1992). Protein folding in the cell: The role of molecular chaperones Hsp70 and Hsp60. Annual Review of Biophysics and Biomolecular Structure, 21, 293-322.
-
(1992)
Annual Review of Biophysics and Biomolecular Structure
, vol.21
, pp. 293-322
-
-
Harti, F.U.1
Martin, J.2
Neupert, W.3
-
29
-
-
13244294100
-
Catalysis and assistance of protein folding
-
Schmid, F. X. (1991). Catalysis and assistance of protein folding. Current Opinion in Structural Biology, 1, 36-41.
-
(1991)
Current Opinion in Structural Biology
, vol.1
, pp. 36-41
-
-
Schmid, F.X.1
-
30
-
-
36749104448
-
"Protein misfolding, aggregation and conformational diseases"
-
Uversky, V. N., & Fink, A. (Eds.). (2006). "Protein misfolding, aggregation and conformational diseases", Part A: Protein aggregation and conformational diseases, series: Protein Reviews, Vol. 4, p. 419.
-
(2006)
Part A: Protein aggregation and conformational diseases, series: Protein Reviews
, vol.4
, pp. 419
-
-
Uversky, V.N.1
Fink, A.2
-
31
-
-
0032006678
-
Alternative conformation of amyloidogenic proteins and their multi-step assembly pathways
-
Kelly, J. (1998). Alternative conformation of amyloidogenic proteins and their multi-step assembly pathways. Current Opinion in Structural Biology, 8, 101-106.
-
(1998)
Current Opinion in Structural Biology
, vol.8
, pp. 101-106
-
-
Kelly, J.1
-
32
-
-
0035961329
-
The structural basis of protein folding and its links with human disease
-
Dobson, C. M. (2001). The structural basis of protein folding and its links with human disease. Philosophical Transactions of the Royal Society London B, 356, 133-145.
-
(2001)
Philosophical Transactions of the Royal Society London B
, vol.356
, pp. 133-145
-
-
Dobson, C.M.1
-
33
-
-
0031056829
-
Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis
-
Booth, D. R., Sunde, M., Bellotti, V., Robinson, C. V., Hutchinson, W. L., et al. (1997). Instability, unfolding and aggregation of human lysozyme variants underlying amyloid fibrillogenesis. Nature, 385, 78-793.
-
(1997)
Nature
, vol.385
, pp. 78-793
-
-
Booth, D.R.1
Sunde, M.2
Bellotti, V.3
Robinson, C.V.4
Hutchinson, W.L.5
-
34
-
-
0028856292
-
Defective protein folding as a basis of human disease
-
Thomas, P. J., Qu, B. H., & Pedersen, P. L. (1995). Defective protein folding as a basis of human disease. Trends in Biochemical Sciences, 20, 456-459.
-
(1995)
Trends in Biochemical Sciences
, vol.20
, pp. 456-459
-
-
Thomas, P.J.1
Qu, B.H.2
Pedersen, P.L.3
-
35
-
-
70049090962
-
Amyloidogenic regions and interaction surfaces overlap in globular proteins related to conformational diseases
-
Castillo, V., & Ventura, S. (2009). Amyloidogenic regions and interaction surfaces overlap in globular proteins related to conformational diseases. PLoS Computational Biology, 5, 1-16.
-
(2009)
PLoS Computational Biology
, vol.5
, pp. 1-16
-
-
Castillo, V.1
Ventura, S.2
-
36
-
-
2942580461
-
CFTR and chaperones processing and degradation
-
Amaral, M. D. (2004). CFTR and chaperones processing and degradation. Journal of Molecular Neuroscience, 23, 41-48.
-
(2004)
Journal of Molecular Neuroscience
, vol.23
, pp. 41-48
-
-
Amaral, M.D.1
-
37
-
-
58149316598
-
Early stages of β2-microglobulin aggregation and the inhibiting action of αB-crystallin
-
Pullara, F., & Emanuele, A. (2008). Early stages of β2-microglobulin aggregation and the inhibiting action of αB-crystallin. Proteins, 73, 1037-1046.
-
(2008)
Proteins
, vol.73
, pp. 1037-1046
-
-
Pullara, F.1
Emanuele, A.2
-
38
-
-
0035139109
-
Cellular defenses against unfolded proteins: A cell biologist thinks about neurodegenerative diseases
-
Sherman, M. Y., & Goldberg, A. L. (2001). Cellular defenses against unfolded proteins: A cell biologist thinks about neurodegenerative diseases. Neuron, 29, 15-32.
-
(2001)
Neuron
, vol.29
, pp. 15-32
-
-
Sherman, M.Y.1
Goldberg, A.L.2
-
39
-
-
0242668337
-
Common structure of soluble amyloid oligomers implies common mechanisms of pathogenesis
-
Kayed, R., Head, E., Thompson, J. L., et al. (2003). Common structure of soluble amyloid oligomers implies common mechanisms of pathogenesis. Science, 300, 486-489.
-
(2003)
Science
, vol.300
, pp. 486-489
-
-
Kayed, R.1
Head, E.2
Thompson, J.L.3
-
40
-
-
0036845354
-
The behaviour of poly amino acids reveals an inverse side chain effect in amyloid structure formation
-
Fandrich, M., & Dobson, C. M. (2002). The behaviour of poly amino acids reveals an inverse side chain effect in amyloid structure formation. EMBO Journal, 21, 5682-5690.
-
(2002)
EMBO Journal
, vol.21
, pp. 5682-5690
-
-
Fandrich, M.1
Dobson, C.M.2
-
41
-
-
33750480868
-
Characterization of the nanoscale properties of individual amyloid fibrils
-
Smith, J. F., Knowles, T. P., Dobson, C. M., et al. (2006). Characterization of the nanoscale properties of individual amyloid fibrils. Proceedings of the National Academy of Sciences of the United States of America, 103, 15806-15811.
-
(2006)
Proceedings of the National Academy of Sciences of the United States of America
, vol.103
, pp. 15806-15811
-
-
Smith, J.F.1
Knowles, T.P.2
Dobson, C.M.3
-
42
-
-
33748520925
-
Diffraction to study protein and peptide assemblies
-
Makin, O. S., Sikorski, P., & Serpell, L. C. (2006). Diffraction to study protein and peptide assemblies. Current Opinion in Chemical Biology, 10, 417-422.
-
(2006)
Current Opinion in Chemical Biology
, vol.10
, pp. 417-422
-
-
Makin, O.S.1
Sikorski, P.2
Serpell, L.C.3
-
43
-
-
0037465708
-
Insights into the amyloid folding problem from solid-state NMR
-
Tycko, R. (2003). Insights into the amyloid folding problem from solid-state NMR. Biochemistry, 42, 3151-3159.
-
(2003)
Biochemistry
, vol.42
, pp. 3151-3159
-
-
Tycko, R.1
-
44
-
-
0037174998
-
Structural and dynamic features of Alzheimer's Aβ peptide in amyloid fibrils studied by site-directed spin labelling
-
Torok, M., Milton, S., Kayed, R., et al. (2002). Structural and dynamic features of Alzheimer's Aβ peptide in amyloid fibrils studied by site-directed spin labelling. Journal of Biological Chemistry, 277, 40810-40815.
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 40810-40815
-
-
Torok, M.1
Milton, S.2
Kayed, R.3
-
45
-
-
0033534397
-
Watching amyloid fibrils grow by time-lapse atomic force microscopy
-
Goldsbury, C., Kistler, J., Aebi, U., et al. (1999). Watching amyloid fibrils grow by time-lapse atomic force microscopy. Journal of Molecular Biology, 285, 33-39.
-
(1999)
Journal of Molecular Biology
, vol.285
, pp. 33-39
-
-
Goldsbury, C.1
Kistler, J.2
Aebi, U.3
-
46
-
-
0034725535
-
The protofilament substructure of amyloid fibrils
-
Serpell, L., Sunde, M., Benson, M., et al. (2000). The protofilament substructure of amyloid fibrils. Journal of Molecular Biology, 300, 1033-1039.
-
(2000)
Journal of Molecular Biology
, vol.300
, pp. 1033-1039
-
-
Serpell, L.1
Sunde, M.2
Benson, M.3
-
47
-
-
0042847751
-
Cryo-electron microscopy structure of an SH3 amyloid fibril and model of the molecular packing
-
Jimenez, J. L., Guijarro, J. I., Orlova, E., et al. (1999). Cryo-electron microscopy structure of an SH3 amyloid fibril and model of the molecular packing. EMBO Journal, 18, 815-821.
-
(1999)
EMBO Journal
, vol.18
, pp. 815-821
-
-
Jimenez, J.L.1
Guijarro, J.I.2
Orlova, E.3
-
48
-
-
0035839046
-
Structural diversity of ex vivo amyloid fibrils studied by cryo-electron microscopy
-
Jimenez, J. L., Tennent, G., Pepys, M. B., et al. (2001). Structural diversity of ex vivo amyloid fibrils studied by cryo-electron microscopy. Journal of Molecular Biology, 311, 241-247.
-
(2001)
Journal of Molecular Biology
, vol.311
, pp. 241-247
-
-
Jimenez, J.L.1
Tennent, G.2
Pepys, M.B.3
-
49
-
-
0037047118
-
The protofilament structure of insulin amyloid fibrils
-
Jimenez, J. L., Nettleton, E. J., Bouchard, M., et al. (2002). The protofilament structure of insulin amyloid fibrils. Proceedings of the National Academy of Sciences of the United States of America, 99, 9196-9201.
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, pp. 9196-9201
-
-
Jimenez, J.L.1
Nettleton, E.J.2
Bouchard, M.3
-
51
-
-
0031825554
-
From the globular to the fibrous state: Protein structure and structural conversion in amyloid formation
-
Sunde, M., & Blake, C. C. (1998). From the globular to the fibrous state: Protein structure and structural conversion in amyloid formation. Quarterly Review of Biophysics, 31, 1-39.
-
(1998)
Quarterly Review of Biophysics
, vol.31
, pp. 1-39
-
-
Sunde, M.1
Blake, C.C.2
-
53
-
-
0037422616
-
Polyglutamine fibrillogenesis: The pathway unfolds
-
Ross, C. A., Michelle, A., Poirier, M. A., Wanker, E. E., & Amzel, M. (2003). Polyglutamine fibrillogenesis: The pathway unfolds. Proceedings of the National Academy of Sciences of the United States of America, 100, 1-3.
-
(2003)
Proceedings of the National Academy of Sciences of the United States of America
, vol.100
, pp. 1-3
-
-
Ross, C.A.1
Michelle, A.2
Poirier, M.A.3
Wanker, E.E.4
Amzel, M.5
-
54
-
-
77955714515
-
Protein folding and aggregation in bacteria
-
Sabate, R., De Groot, N. S., & Ventura, S. (2010). Protein folding and aggregation in bacteria. Cellular and Molecular Life Sciences, 67, 2695-2715.
-
(2010)
Cellular and Molecular Life Sciences
, vol.67
, pp. 2695-2715
-
-
Sabate, R.1
de Groot, N.S.2
Ventura, S.3
-
55
-
-
69149103558
-
Intrinsic disorder in proteins associated with neurodegenerative diseases
-
Uversky, V. N. (2009). Intrinsic disorder in proteins associated with neurodegenerative diseases. Frontier Bioscience, 14, 5188-5238.
-
(2009)
Frontier Bioscience
, vol.14
, pp. 5188-5238
-
-
Uversky, V.N.1
-
56
-
-
3542995049
-
Stress-inducible responses and heat shock proteins: New pharmacologic targets for cytoprotection
-
Morimoto, R. I., & Santoro, M. G. (1998). Stress-inducible responses and heat shock proteins: New pharmacologic targets for cytoprotection. Nature Biotechnology, 16, 833-838.
-
(1998)
Nature Biotechnology
, vol.16
, pp. 833-838
-
-
Morimoto, R.I.1
Santoro, M.G.2
-
57
-
-
33646127577
-
Molecular chaperones and protein quality control
-
Bukau, B., Weissmanand, J., & Horwich, A. (2006). Molecular chaperones and protein quality control. Cell, 125, 445-451.
-
(2006)
Cell
, vol.125
, pp. 445-451
-
-
Bukau, B.1
Weissmanand, J.2
Horwich, A.3
-
58
-
-
0036468432
-
Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease
-
Auluck, P. K., Chan, H. Y., Trojanowsk, J. Q., Lee, V. M., & Bonini, N. M. (2002). Chaperone suppression of alpha-synuclein toxicity in a Drosophila model for Parkinson's disease. Science, 295, 865-868.
-
(2002)
Science
, vol.295
, pp. 865-868
-
-
Auluck, P.K.1
Chan, H.Y.2
Trojanowsk, J.Q.3
Lee, V.M.4
Bonini, N.M.5
-
59
-
-
2942620074
-
Hsp70 reduces alpha-synuclein aggregation and toxicity
-
Klucken, J., Shin, Y., Masliah, E., Hyman, B. T., & McLean, P. J. (2004). Hsp70 reduces alpha-synuclein aggregation and toxicity. Journal of Biological Chemistry, 279, 25497-25502.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 25497-25502
-
-
Klucken, J.1
Shin, Y.2
Masliah, E.3
Hyman, B.T.4
McLean, P.J.5
-
60
-
-
0037059042
-
Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity
-
Sakahira, H., Breuer, P., Hayer-Hartl, M. K., & Hartl, F. U. (2002). Molecular chaperones as modulators of polyglutamine protein aggregation and toxicity. Proceedings of the National Academy of Sciences of the United States of America, 99, 16412-16418.
-
(2002)
Proceedings of the National Academy of Sciences of the United States of America
, vol.99
, pp. 16412-16418
-
-
Sakahira, H.1
Breuer, P.2
Hayer-Hartl, M.K.3
Hartl, F.U.4
-
61
-
-
0023935087
-
Comparison with small heat shock proteins and Schistosoma egg antigen
-
De Jong, W. W., Leunissen, J. A., Leenen, P. J., Zweers, A., & Versteeg, M. (1988). Comparison with small heat shock proteins and Schistosoma egg antigen. Journal of Biological Chemistry, 263, 5141-5149.
-
(1988)
Journal of Biological Chemistry
, vol.263
, pp. 5141-5149
-
-
de Jong, W.W.1
Leunissen, J.A.2
Leenen, P.J.3
Zweers, A.4
Versteeg, M.5
-
62
-
-
0024997813
-
Tissue-specific expression of the heat shock protein HSP27 during Drosophila melanogaster development
-
Pauli, D., Tonka, C. H., Tissieres, A., & Arrigo, A. P. (1990). Tissue-specific expression of the heat shock protein HSP27 during Drosophila melanogaster development. Journal of Cell Biology, 111, 817-828.
-
(1990)
Journal of Cell Biology
, vol.111
, pp. 817-828
-
-
Pauli, D.1
Tonka, C.H.2
Tissieres, A.3
Arrigo, A.P.4
-
63
-
-
0039844535
-
Protection of neuronal cells from apoptosis by Hsp27 delivered with a herpes simplex virus-based vector
-
Wagstaff, M. J., Collaco-Moraes, Y., Smith, J., De Belleroche, J. S., Coffin, R. S., & Latchman, D. S. (1998). Protection of neuronal cells from apoptosis by Hsp27 delivered with a herpes simplex virus-based vector. Journal of Biological Chemistry, 274, 5061-5069.
-
(1998)
Journal of Biological Chemistry
, vol.274
, pp. 5061-5069
-
-
Wagstaff, M.J.1
Collaco-Moraes, Y.2
Smith, J.3
de Belleroche, J.S.4
Coffin, R.S.5
Latchman, D.S.6
-
64
-
-
0032572603
-
Stress (heat shock) proteins: Molecular chaperones in cardiovascular biology and disease
-
Benjamin, I. J., & McMillan, D. R. (1998). Stress (heat shock) proteins: Molecular chaperones in cardiovascular biology and disease. Circulation Research, 83, 117-132.
-
(1998)
Circulation Research
, vol.83
, pp. 117-132
-
-
Benjamin, I.J.1
McMillan, D.R.2
-
65
-
-
0034282104
-
Hsp27 negatively regulates cell death by interacting with cytochrome c
-
Bruey, J. M., Ducasse, C., Bonniaud, P., Ravagnan, L., Susin, S. A., Diaz-Latoud, C., et al. (2000). Hsp27 negatively regulates cell death by interacting with cytochrome c. Nature Cell Biology, 2, 645-652.
-
(2000)
Nature Cell Biology
, vol.2
, pp. 645-652
-
-
Bruey, J.M.1
Ducasse, C.2
Bonniaud, P.3
Ravagnan, L.4
Susin, S.A.5
Diaz-Latoud, C.6
Gurbuxani, S.7
-
66
-
-
0041344614
-
Heat shock protein 27 controls apoptosis by regulating Akt activation
-
Rane, M. J., Pan, Y., Singh, S., Powell, D., Wu, W. R., & Cummins, T. (2003). Heat shock protein 27 controls apoptosis by regulating Akt activation. Journal of Biological Chemistry, 278, 27828-27835.
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 27828-27835
-
-
Rane, M.J.1
Pan, Y.2
Singh, S.3
Powell, D.4
Wu, W.R.5
Cummins, T.6
-
67
-
-
0036566675
-
Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntington
-
Wyttenbach, A., Sauvageot, O., Carmichael, J., Diaz-Latoud, C., Arrigo, A. P., & Rubinsztein, D. C. (2002). Heat shock protein 27 prevents cellular polyglutamine toxicity and suppresses the increase of reactive oxygen species caused by huntington. Human Molecular Genetics, 11, 1137-1151.
-
(2002)
Human Molecular Genetics
, vol.11
, pp. 1137-1151
-
-
Wyttenbach, A.1
Sauvageot, O.2
Carmichael, J.3
Diaz-Latoud, C.4
Arrigo, A.P.5
Rubinsztein, D.C.6
-
68
-
-
1642356755
-
HSP27 but not HSP70 has a potent protective effect against alpha-synuclein-induced cell death in mammalian neuronal cells
-
Zourlidou, A., Payne Smith, M. D., & Latchman, D. S. (2004). HSP27 but not HSP70 has a potent protective effect against alpha-synuclein-induced cell death in mammalian neuronal cells. Journal of Neurochemistry, 88, 1439-1448.
-
(2004)
Journal of Neurochemistry
, vol.88
, pp. 1439-1448
-
-
Zourlidou, A.1
Payne Smith, M.D.2
Latchman, D.S.3
-
69
-
-
77953463398
-
Protein degradation, aggregation and misfolding
-
Cuervo, A. M., Wong, E. S. P., & Martinez-Vicente, M. (2010). Protein degradation, aggregation and misfolding. Movement Disorders, 25, S49-S54.
-
(2010)
Movement Disorders
, vol.25
-
-
Cuervo, A.M.1
Wong, E.S.P.2
Martinez-Vicente, M.3
-
70
-
-
33750363298
-
Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases
-
Rubinsztein, D. C. (2006). Mitochondrial dysfunction and oxidative stress in neurodegenerative diseases. Nature, 443, 780-786.
-
(2006)
Nature
, vol.443
, pp. 780-786
-
-
Rubinsztein, D.C.1
-
71
-
-
34250183177
-
HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS
-
Pandey, U. B., Nie, Z., Batlevi, Y., et al. (2007). HDAC6 rescues neurodegeneration and provides an essential link between autophagy and the UPS. Nature, 447, 859-863.
-
(2007)
Nature
, vol.447
, pp. 859-863
-
-
Pandey, U.B.1
Nie, Z.2
Batlevi, Y.3
-
72
-
-
28844475400
-
HDAC6 and microtubules are required for autophagic degradation of aggregated Huntington
-
Iwata, A., Riley, B. E., Johnston, J. A., & Kopito, R. R. (2005). HDAC6 and microtubules are required for autophagic degradation of aggregated Huntington. Journal of Biological Chemistry, 280, 40282-40292.
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 40282-40292
-
-
Iwata, A.1
Riley, B.E.2
Johnston, J.A.3
Kopito, R.R.4
-
73
-
-
22244442489
-
The biochemistry of Parkinson's disease
-
Cookson, M. R. (2005). The biochemistry of Parkinson's disease. Annual Review of Biochemistry, 74, 29-52.
-
(2005)
Annual Review of Biochemistry
, vol.74
, pp. 29-52
-
-
Cookson, M.R.1
-
74
-
-
0032499264
-
Mutations in the parldn gene cause autosomal recessive juvenile parkinsonism
-
Kitada, T., Asakawa, S., Hattori, N., Matsumine, H., Yamamura, Y., & Minoshima, S. (1998). Mutations in the parldn gene cause autosomal recessive juvenile parkinsonism. Nature, 392, 605-608.
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
Matsumine, H.4
Yamamura, Y.5
Minoshima, S.6
-
75
-
-
0033933048
-
Familial Parkinson's disease gene product, parkin, is an ubiquitin-protein ligase
-
Shimura, H., Hattori, N., Kubo, S., Yoshikuni, K., Mizuno, Y., et al. (2000). Familial Parkinson's disease gene product, parkin, is an ubiquitin-protein ligase. Nature Genetics, 25, 302-305.
-
(2000)
Nature Genetics
, vol.25
, pp. 302-305
-
-
Shimura, H.1
Hattori, N.2
Kubo, S.3
Yoshikuni, K.4
Mizuno, Y.5
-
76
-
-
24144470504
-
The biochemistry of Parkinson's disease
-
Sriram, S. R., Li, X., Ko, H. S., Kenny, K. K., Chung Wong, E., et al. (2005). The biochemistry of Parkinson's disease. Human Molecular Genetics, 14, 2571-2586.
-
(2005)
Human Molecular Genetics
, vol.14
, pp. 2571-2586
-
-
Sriram, S.R.1
Li, X.2
Ko, H.S.3
Kenny, K.K.4
Chung Wong, E.5
-
77
-
-
33745280651
-
Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity
-
Hampe, C., Ardila-Osorio, H., Fournier, M., Alexis, B., & Olga, C. (2006). Biochemical analysis of Parkinson's disease-causing variants of Parkin, an E3 ubiquitin-protein ligase with monoubiquitylation capacity. Human Molecular Genetics, 15, 2059-2207.
-
(2006)
Human Molecular Genetics
, vol.15
, pp. 2059-2207
-
-
Hampe, C.1
Ardila-Osorio, H.2
Fournier, M.3
Alexis, B.4
Olga, C.5
-
78
-
-
33645635706
-
Diverse effects pathogenic mutations of Parkin that catalyze multiple monoub- iquitylation in vitro
-
Matsuda, N., Kitami, T., Suzuki, T., Mizuno, Y., Hattori, N., & Tanaka, K. (2006). Diverse effects pathogenic mutations of Parkin that catalyze multiple monoub- iquitylation in vitro. Journal of Biological Chemistry, 281, 3204-3209.
-
(2006)
Journal of Biological Chemistry
, vol.281
, pp. 3204-3209
-
-
Matsuda, N.1
Kitami, T.2
Suzuki, T.3
Mizuno, Y.4
Hattori, N.5
Tanaka, K.6
-
79
-
-
80955167092
-
Parkin mediates non-classical, proteasomal-independent ubiquitination of synphilin-466
-
Lim, K. L., Chew, K. C., & Tan, J. M. (2009). Parkin mediates non-classical, proteasomal-independent ubiquitination of synphilin-466. Apoptosis, 14, 455-468.
-
(2009)
Apoptosis
, vol.14
, pp. 455-468
-
-
Lim, K.L.1
Chew, K.C.2
Tan, J.M.3
-
80
-
-
33344456519
-
Parkin- mediated lysine 63-linked polyubiquitination: A link to Lewy Body formation
-
Lim, K. L., Dawson, V. L., & Dawson, T. M. (2006). Parkin- mediated lysine 63-linked polyubiquitination: A link to Lewy Body formation. Neurobiology of Aging, 27, 524-529.
-
(2006)
Neurobiology of Aging
, vol.27
, pp. 524-529
-
-
Lim, K.L.1
Dawson, V.L.2
Dawson, T.M.3
-
81
-
-
0026649584
-
The cystic fibrosis transmembrane conductance regulatoreffects of the most common cystic fibrosis-causing mutation on the secondary structure and stability of a synthetic peptide
-
Thomas, P. J., Shenbagamurthi, P., Sondek, J., Hullihen, J. M., & Pedersen, P. L. (1992). The cystic fibrosis transmembrane conductance regulatoreffects of the most common cystic fibrosis-causing mutation on the secondary structure and stability of a synthetic peptide. Journal of Biological Chemistry, 267, 5727-5730.
-
(1992)
Journal of Biological Chemistry
, vol.267
, pp. 5727-5730
-
-
Thomas, P.J.1
Shenbagamurthi, P.2
Sondek, J.3
Hullihen, J.M.4
Pedersen, P.L.5
-
82
-
-
77954681706
-
The missing zinc: p53 misfolding and cancer
-
Stewart Loh, N. (2010). The missing zinc: p53 misfolding and cancer. Metallomics, 2, 442-449.
-
(2010)
Metallomics
, vol.2
, pp. 442-449
-
-
Stewart Loh, N.1
-
83
-
-
63749109353
-
Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: A novel disease mechanism
-
Kereszturi, E., Szmola, R., Kukor, Z., et al. (2009). Hereditary pancreatitis caused by mutation-induced misfolding of human cationic trypsinogen: A novel disease mechanism. Human Mutation, 30, 575-582.
-
(2009)
Human Mutation
, vol.30
, pp. 575-582
-
-
Kereszturi, E.1
Szmola, R.2
Kukor, Z.3
-
84
-
-
0024296032
-
Endothelium derived relaxing factor release on activation of NMDA receptors suggests role as intracellular messenger in the brain
-
Garthwaite, J., Charles, S. L., & Chess-Williams, R. (1988). Endothelium derived relaxing factor release on activation of NMDA receptors suggests role as intracellular messenger in the brain. Nature, 336, 385-388.
-
(1988)
Nature
, vol.336
, pp. 385-388
-
-
Garthwaite, J.1
Charles, S.L.2
Chess-Williams, R.3
-
85
-
-
0025802065
-
Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase
-
Bredt, D. S., Hwang, P. M., Glatt, C. E., Lowenstein, C., Reed, R. R., & snyder, S. H. (1991). Cloned and expressed nitric oxide synthase structurally resembles cytochrome P-450 reductase. Nature, 351, 714-718.
-
(1991)
Nature
, vol.351
, pp. 714-718
-
-
Bredt, D.S.1
Hwang, P.M.2
Glatt, C.E.3
Lowenstein, C.4
Reed, R.R.5
Snyder, S.H.6
-
86
-
-
33745315287
-
S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration
-
Uehara, T., Nakamura, T., Yao, D., Shi, Z. Q., et al. (2006). S-nitrosylated protein-disulphide isomerase links protein misfolding to neurodegeneration. Nature, 441, 513-517.
-
(2006)
Nature
, vol.441
, pp. 513-517
-
-
Uehara, T.1
Nakamura, T.2
Yao, D.3
Shi, Z.Q.4
-
87
-
-
3242733689
-
Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity
-
Yao, D., Gu, Z., Nakamura, T., Shi, Z. Q., Ma, Y., et al. (2004). Nitrosative stress linked to sporadic Parkinson's disease: S-nitrosylation of parkin regulates its E3 ubiquitin ligase activity. Proceedings of the National Academy of Sciences of the United States of America, 101, 10810-10814.
-
(2004)
Proceedings of the National Academy of Sciences of the United States of America
, vol.101
, pp. 10810-10814
-
-
Yao, D.1
Gu, Z.2
Nakamura, T.3
Shi, Z.Q.4
Ma, Y.5
-
88
-
-
34447131004
-
Molecular mechanisms of nitrosative stress-mediated protein misfolding in neurodegenerative diseases
-
Nakamura, T., & Lipton, S. A. (2007). Molecular mechanisms of nitrosative stress-mediated protein misfolding in neurodegenerative diseases. Cellular and Molecular Life Sciences, 64, 1609-1620.
-
(2007)
Cellular and Molecular Life Sciences
, vol.64
, pp. 1609-1620
-
-
Nakamura, T.1
Lipton, S.A.2
-
89
-
-
64149118386
-
Post translational modifications of tubulin in nervous system
-
Fukushima, N., Furuta, D., Hidaka, Y., Moriyama, R., & Tsujiuchi, T. (2009). Post translational modifications of tubulin in nervous system. Journal of Neurochemistry, 109, 683-693.
-
(2009)
Journal of Neurochemistry
, vol.109
, pp. 683-693
-
-
Fukushima, N.1
Furuta, D.2
Hidaka, Y.3
Moriyama, R.4
Tsujiuchi, T.5
-
90
-
-
19944432234
-
Argpyrimidine, a methylglyoxal-derived advanced glycation end-product in familial amyloidotic polyneuropathy
-
Gomes, R., Sousasilva, M., Quintas, A., Cordeiro, C., et al. (2005). Argpyrimidine, a methylglyoxal-derived advanced glycation end-product in familial amyloidotic polyneuropathy. Biochemical Journal, 385, 339-345.
-
(2005)
Biochemical Journal
, vol.385
, pp. 339-345
-
-
Gomes, R.1
Sousasilva, M.2
Quintas, A.3
Cordeiro, C.4
-
93
-
-
0019796775
-
Kinetic analysis of the non enzymatic glycosylation of hemoglobin
-
Bunn, H. F., & Higgins, P. J. (1981). Kinetic analysis of the non enzymatic glycosylation of hemoglobin. Journal of Biological Chemistry, 213, 222-224.
-
(1981)
Journal of Biological Chemistry
, vol.213
, pp. 222-224
-
-
Bunn, H.F.1
Higgins, P.J.2
-
94
-
-
33746377894
-
Protein misfolding, functional amyloid, and human disease
-
Chiti, F., & Dobson, C. M. (2006). Protein misfolding, functional amyloid, and human disease. Annual Review of Biochemistry, 75, 333-366.
-
(2006)
Annual Review of Biochemistry
, vol.75
, pp. 333-366
-
-
Chiti, F.1
Dobson, C.M.2
-
95
-
-
0037174618
-
Alzheimer's disease is a synaptic failure
-
Selkoe, D. J. (2002). Alzheimer's disease is a synaptic failure. Science, 298, 789-791.
-
(2002)
Science
, vol.298
, pp. 789-791
-
-
Selkoe, D.J.1
-
96
-
-
0037135111
-
The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics
-
Hardy, J., & Selkoe, D. J. (2002). The amyloid hypothesis of Alzheimer's disease: Progress and problems on the road to therapeutics. Science, 297, 353-356.
-
(2002)
Science
, vol.297
, pp. 353-356
-
-
Hardy, J.1
Selkoe, D.J.2
-
97
-
-
0034716942
-
Direct visualisation of the beta-sheet structure of synthetic Alzheimer's amyloid
-
Serpell, L. C., & Smith, J. M. (2000). Direct visualisation of the beta-sheet structure of synthetic Alzheimer's amyloid. Journal of Molecular Biology, 299, 225-231.
-
(2000)
Journal of Molecular Biology
, vol.299
, pp. 225-231
-
-
Serpell, L.C.1
Smith, J.M.2
-
98
-
-
0035943345
-
A portrait of Alzheimer secretases-new features and familiar faces
-
Esler, W. P., & Wolfe, M. S. (2001). A portrait of Alzheimer secretases-new features and familiar faces. Science, 293, 1449-1454.
-
(2001)
Science
, vol.293
, pp. 1449-1454
-
-
Esler, W.P.1
Wolfe, M.S.2
-
99
-
-
0036828769
-
Alzheimer's disease: Treatments in discovery and development
-
Citron, M. (2002). Alzheimer's disease: Treatments in discovery and development. Nature Neuroscience, 5, 1055-1057.
-
(2002)
Nature Neuroscience
, vol.5
, pp. 1055-1057
-
-
Citron, M.1
-
100
-
-
0028363366
-
Advanced glycation end products contribute to amyloidosis in Alzheimer disease
-
Michael, P., Vitek, T., Bhattacharya, K. J., et al. (1994). Advanced glycation end products contribute to amyloidosis in Alzheimer disease. Proceedings of the National Academy of Sciences of the United States of America, 91, 4766-4770.
-
(1994)
Proceedings of the National Academy of Sciences of the United States of America
, vol.91
, pp. 4766-4770
-
-
Michael, P.1
Vitek, T.2
Bhattacharya, K.J.3
-
101
-
-
0025733411
-
In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity
-
Pike, C., Walencewicz, A., Glabe, C., & Cotman, C. (1991). In vitro aging of beta-amyloid protein causes peptide aggregation and neurotoxicity. European Journal of Pharmacology, 207, 367-368.
-
(1991)
European Journal of Pharmacology
, vol.207
, pp. 367-368
-
-
Pike, C.1
Walencewicz, A.2
Glabe, C.3
Cotman, C.4
-
102
-
-
0027447286
-
Neurodegeneration induced by beta-amyloid peptides in vitro: The role of peptide assembly state
-
Pike, C., Burdick, D., Walencewicz, A., Glabe, C., & Cotman, C. (1993). Neurodegeneration induced by beta-amyloid peptides in vitro: The role of peptide assembly state. Journal of Neuroscience, 13, 1676-1687.
-
(1993)
Journal of Neuroscience
, vol.13
, pp. 1676-1687
-
-
Pike, C.1
Burdick, D.2
Walencewicz, A.3
Glabe, C.4
Cotman, C.5
-
104
-
-
0031990490
-
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
-
Kruger, R., Kuhn, W., Muller, T., et al. (1998). Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nature Genetics, 18, 106-108.
-
(1998)
Nature Genetics
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
-
105
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos, M. H., et al. (1997). Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science, 276, 2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
-
106
-
-
49649125680
-
CHIP targets toxic α-synuclein oligomers for degradation
-
Tetzlaff, J. E., Putcha, P., Outeiro, T. F., et al. (2008). CHIP targets toxic α-synuclein oligomers for degradation. The Journal of Biological Chemistry, 283, 17962-17968.
-
(2008)
The Journal of Biological Chemistry
, vol.283
, pp. 17962-17968
-
-
Tetzlaff, J.E.1
Putcha, P.2
Outeiro, T.F.3
-
107
-
-
0031910093
-
Aggregation of neurofilament and alpha-synuclein proteins in Lewy bodies: Implications for the pathogenesis of Parkinson disease and Lewy body dementia
-
Trojanowski, J., & Lee, V. (1998). Aggregation of neurofilament and alpha-synuclein proteins in Lewy bodies: Implications for the pathogenesis of Parkinson disease and Lewy body dementia. Archives of Neurology, 55, 151-152.
-
(1998)
Archives of Neurology
, vol.55
, pp. 151-152
-
-
Trojanowski, J.1
Lee, V.2
-
108
-
-
3142514201
-
Protein aggregation and neurodegenerative diseases
-
Ross, R. A., & Poirier, M. A. (2004). Protein aggregation and neurodegenerative diseases. Nature Medicine, 10, S10-S17.
-
(2004)
Nature Medicine
, vol.10
-
-
Ross, R.A.1
Poirier, M.A.2
-
109
-
-
0035115942
-
Progression of symptoms in the early and middle stages of Huntington disease
-
Kirkwood, S. C., Su, J. L., Conneally, P., & Foroud, T. (2001). Progression of symptoms in the early and middle stages of Huntington disease. Archives of Neurology, 58, 273-278.
-
(2001)
Archives of Neurology
, vol.58
, pp. 273-278
-
-
Kirkwood, S.C.1
Su, J.L.2
Conneally, P.3
Foroud, T.4
-
110
-
-
18544410106
-
Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation
-
Davies, S. W., Turmaine, M., Cozens, B. A., et al. (1997). Formation of neuronal intranuclear inclusions underlies the neurological dysfunction in mice transgenic for the HD mutation. Cell, 90, 537-548.
-
(1997)
Cell
, vol.90
, pp. 537-548
-
-
Davies, S.W.1
Turmaine, M.2
Cozens, B.A.3
-
111
-
-
0033551063
-
Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: Implications for Huntington's disease pathology
-
Scherzinger, E., Sittler, A., Schweiger, K., Heiser, V., et al. (1999). Self-assembly of polyglutamine-containing huntingtin fragments into amyloid-like fibrils: Implications for Huntington's disease pathology. Proceedings of the National Academy of Sciences of the United States of America, 96, 4604-4609.
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, pp. 4604-4609
-
-
Scherzinger, E.1
Sittler, A.2
Schweiger, K.3
Heiser, V.4
-
112
-
-
0035997016
-
Protein aggregation in Huntington's disease
-
Hoffner, G., & Djian, P. (2002). Protein aggregation in Huntington's disease. Biochimie, 84, 273-278.
-
(2002)
Biochimie
, vol.84
, pp. 273-278
-
-
Hoffner, G.1
Djian, P.2
-
113
-
-
0032450856
-
Amyloid formation by mutant huntingtin: Threshold, progressivity and recruitment of normal polyglutamine proteins
-
Huang, C. C., Faber, P. W., Persichetti, F., et al. (1998). Amyloid formation by mutant huntingtin: Threshold, progressivity and recruitment of normal polyglutamine proteins. Somatic Cell and Molecular Genetics, 24, 217-233.
-
(1998)
Somatic Cell and Molecular Genetics
, vol.24
, pp. 217-233
-
-
Huang, C.C.1
Faber, P.W.2
Persichetti, F.3
-
114
-
-
0033613212
-
Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells
-
Kazantsev, A., Preisinger, E., Dranovsky, A., Goldgaber, D., & Housman, D. (1999). Insoluble detergent-resistant aggregates form between pathological and nonpathological lengths of polyglutamine in mammalian cells. Proceedings of the National Academy of Sciences of the United States of America, 96, 11404-11409.
-
(1999)
Proceedings of the National Academy of Sciences of the United States of America
, vol.96
, pp. 11404-11409
-
-
Kazantsev, A.1
Preisinger, E.2
Dranovsky, A.3
Goldgaber, D.4
Housman, D.5
-
115
-
-
84857995882
-
TDP-43, protein aggregation, and amyotrophic lateral sclerosis
-
Véronique, V. B., Hussein, D., Patrick, A. D., Edor, K., Rouleau Guy, A. R., & Paul, V. N. (2010). TDP-43, protein aggregation, and amyotrophic lateral sclerosis. US Neurology, 5, 35-38.
-
(2010)
US Neurology
, vol.5
, pp. 35-38
-
-
Véronique, V.B.1
Hussein, D.2
Patrick, A.D.3
Edor, K.4
Rouleau Guy, A.R.5
Paul, V.N.6
-
116
-
-
0019850528
-
Amyotrophic lateral sclerosis and its association with dementia, Parkinsonism and other neurological disorders: A review
-
Hudson, A. J. (1981). Amyotrophic lateral sclerosis and its association with dementia, Parkinsonism and other neurological disorders: A review. Brain, 104, 217-247.
-
(1981)
Brain
, vol.104
, pp. 217-247
-
-
Hudson, A.J.1
-
117
-
-
34249751076
-
TDP43 is a human low molecular weight neurofilament (hNFL) mRNAbinding protein
-
Strong, M. J., Volkening, K., Hammond, R., et al. (2007). TDP43 is a human low molecular weight neurofilament (hNFL) mRNAbinding protein. Molecular and Cellular Neuroscience, 35, 320-327.
-
(2007)
Molecular and Cellular Neuroscience
, vol.35
, pp. 320-327
-
-
Strong, M.J.1
Volkening, K.2
Hammond, R.3
-
118
-
-
33749632259
-
Ubiquitinated TDP-43 in fronto temporal lobar degeneration and amyotrophic lateral sclerosis
-
Neumann, M., Sampathu, D. M., Kwong, L. K., et al. (2006). Ubiquitinated TDP-43 in fronto temporal lobar degeneration and amyotrophic lateral sclerosis. Science, 314, 130-133.
-
(2006)
Science
, vol.314
, pp. 130-133
-
-
Neumann, M.1
Sampathu, D.M.2
Kwong, L.K.3
-
119
-
-
33750716074
-
TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis
-
Arai, T., Hasegawa, M., Akiyama, H., et al. (2006). TDP-43 is a component of ubiquitin-positive tau-negative inclusions in frontotemporal lobar degeneration and amyotrophic lateral sclerosis. Biochemical and Biophysical Research Communications, 351, 602-611.
-
(2006)
Biochemical and Biophysical Research Communications
, vol.351
, pp. 602-611
-
-
Arai, T.1
Hasegawa, M.2
Akiyama, H.3
-
120
-
-
34249946466
-
Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations
-
Mackenzie, I. R., Bigio, E. H., Ince, P. G., et al. (2007). Pathological TDP-43 distinguishes sporadic amyotrophic lateral sclerosis from amyotrophic lateral sclerosis with SOD1 mutations. Annals of Neurology, 61, 427-434.
-
(2007)
Annals of Neurology
, vol.61
, pp. 427-434
-
-
Mackenzie, I.R.1
Bigio, E.H.2
Ince, P.G.3
-
121
-
-
0032199307
-
Cataract as a conformational disease: The Maillard reaction, alpha-crystallin and chemotherapy
-
Crabbe, M. J. (1998). Cataract as a conformational disease: The Maillard reaction, alpha-crystallin and chemotherapy. Cellular and Molecular Biology, 44, 1047-1050.
-
(1998)
Cellular and Molecular Biology
, vol.44
, pp. 1047-1050
-
-
Crabbe, M.J.1
-
122
-
-
0031464278
-
Molecular evidence for the involvement of alpha crystallin in the coloration/crosslinking of crystallins in age related nuclear cataract
-
Chen, Y. C., Reid, G. E., Simpson, R. J., & Truscott, R. J. (1997). Molecular evidence for the involvement of alpha crystallin in the coloration/crosslinking of crystallins in age related nuclear cataract. Experimental Eye Research, 65, 835-840.
-
(1997)
Experimental Eye Research
, vol.65
, pp. 835-840
-
-
Chen, Y.C.1
Reid, G.E.2
Simpson, R.J.3
Truscott, R.J.4
-
124
-
-
0942276377
-
Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation
-
Meehan, S., Berry, Y., Luisi, B., Dobson, C. M., Carver, J. A., & MacPhee, C. E. (2004). Amyloid fibril formation by lens crystallin proteins and its implications for cataract formation. Journal of Biological Chemistry, 279, 3413-3419.
-
(2004)
Journal of Biological Chemistry
, vol.279
, pp. 3413-3419
-
-
Meehan, S.1
Berry, Y.2
Luisi, B.3
Dobson, C.M.4
Carver, J.A.5
Macphee, C.E.6
-
125
-
-
57649131080
-
Identification of the primary targets of carbamylation in bovine lens proteins by mass spectrometry
-
Zhang, J., Yan, H., Harding, J. J., Liu, Z. X., Wang, X., & Ruan, Y. S. (2008). Identification of the primary targets of carbamylation in bovine lens proteins by mass spectrometry. Current Eye Research, 33, 963-976.
-
(2008)
Current Eye Research
, vol.33
, pp. 963-976
-
-
Zhang, J.1
Yan, H.2
Harding, J.J.3
Liu, Z.X.4
Wang, X.5
Ruan, Y.S.6
-
126
-
-
0032941652
-
Cataract mutations and lens development
-
Graw, J. (1999). Cataract mutations and lens development. Progress in Retinal and Eye Research, 18, 235-267.
-
(1999)
Progress in Retinal and Eye Research
, vol.18
, pp. 235-267
-
-
Graw, J.1
-
127
-
-
61849122908
-
Genetics of crystallins: Cataract and beyond
-
Graw, J. (2009). Genetics of crystallins: Cataract and beyond. Experimental Eye Research, 88, 173-189.
-
(2009)
Experimental Eye Research
, vol.88
, pp. 173-189
-
-
Graw, J.1
-
128
-
-
65249160170
-
The structure of the cataract-causing P23T mutant of human gamma d-crystallin exhibits distinctive local conformational and dynamic changes
-
Jung, J., Byeon, I. J., Wang, Y., King, J., & Gronenborn, A. M. (2009). The structure of the cataract-causing P23T mutant of human gamma d-crystallin exhibits distinctive local conformational and dynamic changes. Biochemistry, 48, 2597-2609.
-
(2009)
Biochemistry
, vol.48
, pp. 2597-2609
-
-
Jung, J.1
Byeon, I.J.2
Wang, Y.3
King, J.4
Gronenborn, A.M.5
-
129
-
-
18744404774
-
Altered aggregation properties of mutant g-crystallins cause inherited cataract
-
Sandilands, A., Hutcheson, A. M., Long, H. A., et al. (2002). Altered aggregation properties of mutant g-crystallins cause inherited cataract. EMBO Journal, 21, 6005-6014.
-
(2002)
EMBO Journal
, vol.21
, pp. 6005-6014
-
-
Sandilands, A.1
Hutcheson, A.M.2
Long, H.A.3
-
130
-
-
0031426167
-
Cystic fibrosis: A disease of altered protein folding
-
Qu, B. H., Strickland, E., & Thomas, P. J. (1997). Cystic fibrosis: A disease of altered protein folding. Journal of Bioenergetics and Biomembranes, 29, 483-490.
-
(1997)
Journal of Bioenergetics and Biomembranes
, vol.29
, pp. 483-490
-
-
Qu, B.H.1
Strickland, E.2
Thomas, P.J.3
-
131
-
-
0029870085
-
Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid
-
Smith, J. J., Travis, S. M., Greenberg, E. P., & Welsh, M. J. (1996). Cystic fibrosis airway epithelia fail to kill bacteria because of abnormal airway surface fluid. Cell, 85, 229-236.
-
(1996)
Cell
, vol.85
, pp. 229-236
-
-
Smith, J.J.1
Travis, S.M.2
Greenberg, E.P.3
Welsh, M.J.4
-
132
-
-
0030021470
-
Role of mutant CFTR in hyper susceptibility of cystic fibrosis patients to lung infections
-
Pier, G. B., Grout, M., Zaidi, T. S., Olsen, J. C., Johnson, L. G., Yankaskas, J. R., et al. (1996). Role of mutant CFTR in hyper susceptibility of cystic fibrosis patients to lung infections. Science, 271, 64-67.
-
(1996)
Science
, vol.271
, pp. 64-67
-
-
Pier, G.B.1
Grout, M.2
Zaidi, T.S.3
Olsen, J.C.4
Johnson, L.G.5
Yankaskas, J.R.6
Goldberg, J.B.7
-
133
-
-
0025349031
-
Cystic fibrosis: A disease in electrolyte transport
-
Quinton, P. M. (1990). Cystic fibrosis: A disease in electrolyte transport. FASEB Journal, 4, 2709-2717.
-
(1990)
FASEB Journal
, vol.4
, pp. 2709-2717
-
-
Quinton, P.M.1
-
134
-
-
0026649584
-
The cystic fibrosis transmembrane conductance regulator
-
Thomas, P. J., et al. (1992). The cystic fibrosis transmembrane conductance regulator. Journal of Biological Chemistry, 267, 5727-5730.
-
(1992)
Journal of Biological Chemistry
, vol.267
, pp. 5727-5730
-
-
Thomas, P.J.1
-
135
-
-
14844303721
-
Inhibition of heparin-induced tau filament formation by phenotiazines, polyphenols, and porphyrins
-
Taniguchi, S., Suzuki, N., Masuda, M., Hisanaga, S., Iwatsubo, T., Goedert, M., et al. (2005). Inhibition of heparin-induced tau filament formation by phenotiazines, polyphenols, and porphyrins. Journal of Biological Chemistry, 280, 7614-7623.
-
(2005)
Journal of Biological Chemistry
, vol.280
, pp. 7614-7623
-
-
Taniguchi, S.1
Suzuki, N.2
Masuda, M.3
Hisanaga, S.4
Iwatsubo, T.5
Goedert, M.6
Hasegawa, M.7
-
136
-
-
0035349804
-
Inhibition of Alzheimer's disease-amyloid aggregation, neurotoxicity, and in vivo deposition by nitrophenols: Implications for Alzheimer's therapy
-
De Felice, F., Houzel, J. C., Garcia-Abreu, J., Louzada, P., Afonso, R. C., & Meirelles, M. N. (2001). Inhibition of Alzheimer's disease-amyloid aggregation, neurotoxicity, and in vivo deposition by nitrophenols: Implications for Alzheimer's therapy. FASEB Journal, 15, 1297-1299.
-
(2001)
FASEB Journal
, vol.15
, pp. 1297-1299
-
-
de Felice, F.1
Houzel, J.C.2
Garcia-Abreu, J.3
Louzada, P.4
Afonso, R.C.5
Meirelles, M.N.6
-
137
-
-
0036544598
-
Inhibition of transthyretin amyloid fibril formation by 2,4-dinitrophenol through tetramer stabilization
-
Raghu, P., Reddy, G. B., & Sivakumar, B. (2002). Inhibition of transthyretin amyloid fibril formation by 2, 4-dinitrophenol through tetramer stabilization. Archives of Biochemistry and Biophysics, 400, 43-47.
-
(2002)
Archives of Biochemistry and Biophysics
, vol.400
, pp. 43-47
-
-
Raghu, P.1
Reddy, G.B.2
Sivakumar, B.3
-
138
-
-
0142164890
-
Protein aggregation and amyloid fibril formation by an SH3 domain probed by limited proteolysis
-
Polverino de Laureto, P., Taddei, N., Frare, E., Capanni, C., Costantini, S., Zurdo, J., Chiti, F., Dobson, C. M., & Fontana, A. (2003). Protein aggregation and amyloid fibril formation by an SH3 domain probed by limited proteolysis. Journal of Molecular Biology, 334, 129-141.
-
(2003)
Journal of Molecular Biology
, vol.334
, pp. 129-141
-
-
Polverino de Laureto, P.1
Taddei, N.2
Frare, E.3
Capanni, C.4
Costantini, S.5
Zurdo, J.6
Chiti, F.7
Dobson, C.M.8
Fontana, A.9
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