Polyglutamine fibrillogenesis: The pathway unfolds

Proceedings of the National Academy of Sciences of the United States of America

Volumn 100, Issue 1, 2003, Pages 1-3

  Ross, Christopher A ^b   Poirier, Michelle A ^b   Wanker, Erich E ^a   Amzel, Mario ^b  

^a MAX DELBRÜCK CENTER FOR MOLECULAR MEDICINE   (Germany)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIC AMP RESPONSIVE ELEMENT BINDING PROTEIN BINDING PROTEIN; GLYCINE; POLYGLUTAMINE; PROLINE; TRANSCRIPTION FACTOR;

AMINO ACID SEQUENCE; ATOMIC FORCE MICROSCOPY; COMPUTER MODEL; CYTOTOXICITY; DEGENERATIVE DISEASE; DENTATORUBROPALLIDOLUYSIAN ATROPHY; EXON; GENE FUNCTION; GENE MUTATION; GENE STRUCTURE; HUNTINGTON CHOREA; MUTATIONAL ANALYSIS; NEUROFILAMENT; NEUROPATHOLOGY; NOTE; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; OLIGOMERIZATION; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN AGGREGATION; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN STRUCTURE; PROTEIN SYNTHESIS; RAMAN SPECTROMETRY; SEQUENCE HOMOLOGY; SPINOCEREBELLAR DEGENERATION; X RAY DIFFRACTION;

HUMANS; MICROFIBRILS; MODELS, MOLECULAR; NEURODEGENERATIVE DISEASES; PEPTIDES; TRINUCLEOTIDE REPEATS;

EID: 0037422616     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0237018100     Document Type: Note

References (48)

1. Fischbeck, K. H. (2001) Brain Res. Bull. 56, 161-163.
2. Huang, C. C., Faber, P. W., Persichetti, F., Mittal, V., Vonsattel, J. P., MacDonald, M. E. & Gusella, J. F. (1998) Somatic Cell Mol. Genet. 24, 217-233.
3. Zoghbi, H. Y. & Orr, H. T. (2000) Annu. Rev. Neurosci. 23, 217-247.
4. Ross, C. (2002) Neuron 35, 819-822.
5. Ross, C. A. (1995) Neuron 15, 493-496.
6. Orr, H. T. (2001) Genes Dev. 15, 925-932.
7. DiFiglia, M., Sapp, E., Chase, K. O., Davies, S. W., Bates, G. P., Vonsattel, J. P. & Aronin, N. (1997) Science 277, 1990-1993.
8. Becher, M. W., Kotzuk, J. A., Sharp, A. H., Davies, S. W., Bates, G. P., Price, D. L. & Ross, C. A. (1998) Neurobiol. Dis. 4, 387-397.
9. Kuemmerle, S., Gutekunst, C. A., Klein, A. M., Li, X. J., Li, S. H., Beal, M. F., Hersch, S. M. & Ferrante, R. J. (1999) Ann. Neurol. 46, 842-849.
10. Davies, S. W., Turmaine, M., Cozens, B. A., DiFiglia, M., Sharp, A. H., Ross, C. A., Scherzinger, E., Wanker, E. E., Mangiarini, L. & Bates, G. P. (1997) Cell 90, 537-548.
11. Saudou, F., Finkbeiner, S., Devys, D. & Greenberg, M. E. (1998) Cell 95, 55-66.
12. Cummings, C. J., Reinstein, E., Sun, Y., Antalffy, B., Jiang, Y., Ciechanover, A., Orr, H. T., Beaudet, A. L. & Zoghbi, H. Y. (1999) Neuron 24, 879-892.
13. Kopito, R. R. (2000) Trends Cell Biol. 10, 524-530.
14. Scherzinger, E., Lurz, R., Turmaine, M., Mangiarini, L., Hollenbach, B., Hasenbank, R., Bates, G. P., Davies, S. W., Lerach, H. & Wanker, E. E. (1997) Cell 90, 549-558.
15. Scherzinger, E., Sittier, A., Schweiger, K., Heiser, V., Lurz, R., Hasenbank, R., Bates, G. P., Lehrach, H. & Wanker, E. E. (1999) Proc. Natl. Acad. Sci. USA 96, 4604-4609.
16. Serpell, L. C., Berriman, J., Jakes, R., Goedert, M. & Crowther, R. A. (2000) Proc. Natl. Acad. Sci. USA 97, 4897-4902.
17. Rochet, J. C. & Lansbury, P. T., Jr. (2000) Curr. Opin. Struct. Biol. 10, 60-68.
18. Serio, T. R., Cashikar, A. G., Kowal, A. S., Sawicki, G. J., Moslehi, J. J., Serpell, L., Arnsdorf, M. F. & Lindquist, S. L. (2000) Science 289, 1317-1321.
19. Perutz, M. (1994) in Protein Science (Cambridge Univ. Press, London), pp. 1629-1637.
20. Perutz, M. F. (1999) Brain Res. Bull. 50, 467.
21. Lathrop, R. H., Casale, M., Tobias, D. J., Marsh, J. L. & Thompson, L. M. (1998) Proc. Int. Conf. Intell. Syst. Mol. Biol. 6, 105-114.
22. Starikov, E. B., Lehrach, H. & Wanker, E. E. (1999) J. Biomol. Struct. Dyn. 17, 409-427.
23. Perutz, M. F., Pope, B. J., Owen, D., Wanker, E. E. & Scherzinger, E. (2002) Proc. Natl. Acad. Sci. USA 99, 5596-5600.
24. Perutz, M. F., Finch, J. T., Berriman, J. & Lesk, A. (2002) Proc. Natl. Acad. Sci. USA 99, 5591-5595.
25. Chen, S., Berthelier, V., Yang, W. & Wetzel, R. (2001) J. Mol. Biol. 311, 173-182.
26. Masino, L., Kelly, G., Leonard, K., Trottier, Y. & Pastore, A. (2002) FEBS Lett. 513, 267-272.
27. Altschuler, E. L., Hud, N. V., Mazrimas, J. A. & Rupp, B. (1997) J. Pept. Res. 50, 73-75.
28. Chen, S., Ferrone, F. A. & Wetzel, R. (2002) Proc. Natl. Acad. Sci. USA 99, 11884-11889.
29. Poirier, M. A., Li, H., Macosko, J., Cai, S., Amzel, M. & Ross, C. A. (2002) J. Biol. Chem. 277, 41032-41037.
30. Thakur, A. K. & Wetzel, R. (2002) Proc. Natl. Acad. Sci. USA 99, 17014-17019.
31. Nucifora, F. C., Jr., Sasaki, M., Peters, M. F., Huang, H., Cooper, J. K., Yamada, M., Takahashi, H., Tsuji, S., Troncoso, J., Dawson, V. L., et al. (2001) Science 291, 2423-2428.
32. McCampbell, A., Taylor, J. P., Taye, A. A., Robitschek, J., Li, M., Walcott, J., Merry, D., Chai, Y., Paulson, H., Sobue, G., et al. (2000) Hum. Mol. Genet. 9, 2197-2202.
33. McCampbell, A., Taye, A. A., Whitty, L., Penney, E., Steffan, J. S. & Fischbeck, K. H. (2001) Proc. Natl. Acad. Sci. USA 98, 15179-15184.
34. Zuccato, C., Ciammola, A., Rigamonti, D., Leavitt, B. R., Goffredo, D., Conti, L., MacDonald, M. E., Friedlander, R. M., Silani, V., Hayden, M. R., et al. (2001) Science 293, 493-498.
35. Steffan, J. S., Kazantsev, A., Spasic-Boskovic, O., Greenwald, M., Zhu, Y. Z., Gohler, H., Wanker, E. E., Bates, G. P., Housman, D. E. & Thompson, L. M. (2000) Proc. Natl. Acad. Sci. USA 97, 6763-6768.
36. Steffan, J. S., Bodai, L., Pallos, J., Poelman, M., McCampbell, A., Apostol, B. L., Kazantsev, A., Schmidt, E., Zhu, Y. Z., Greenwald, M., et al. (2001) Nature 413, 739-743.
37. Shimohata, T., Nakajima, T., Yamada, M., Uchida, C., Onodera, O., Naruse, S., Kimura, T., Koide, R., Nozaki, K., Sano, Y., et al. (2000) Nat. Genet. 26, 29-36.
38. Dunah, A. W., Jeong, H., Griffin, A., Kim, Y. M., Standaert, D. G., Hersch, S. M., Mouradian, M. M., Young, A. B., Tanese, N. & Krainc, D. (2002) Science 296, 2238-2243.
39. Bence, N. F., Sampat, R. M. & Kopito, R. R. (2001) Science 292, 1552-1555.
40. Waelter, S., Boeddrich, A., Lurz, R., Scherzinger, E., Lueder, G., Lehrach, H. & Wanker, E. E. (2001) Mol. Biol. Cell 12, 1393-1407.
41. Yang, W., Dunlap, J. R., Andrews, R. B. & Wetzel, R. (2002) Hum. Mol. Genet. 11, 2905-2917.
42. Heiser, V., Scherzinger, E., Boeddrich, A., Nordhoff, E., Lurz, R., Schugardt, N., Lehrach, H. & Wanker, E. E. (2000) Proc. Natl. Acad. Sci. USA 97, 6739-6744.
43. Heiser, V., Engemann, S., Bröcker, W., Dunkel, I., Boeddrich, A., Waelter, S., Nordhoff, E., Lurz, R., Schugardt, N., Rautenberg, S., et al. (2002) Proc. Natl. Acad. Sci. USA 99 (Suppl. 4), 16400-16046.
44. Kazantsev, A., Walker, H. A., Slepko, N., Bear, J. E., Preisinger, E., Steffan, J. S., Zhu, Y. Z., Gertler, F. B., Housman, D. E., Marsh, J. L., et al. (2002) Nat. Genet. 30, 367-376.
45. Khoshnan, A., Ko, J. & Patterson, P. H. (2002) Proc. Natl. Acad. Sci. USA 99, 1002-1007.
46. Marsh, J. L., Walker, H., Theisen, H., Zhu, Y. Z., Fielder, T., Purcell, J. & Thompson, L. M. (2000) Hum. Mol. Genet. 9, 13-25.
47. Sacchettini, J. C. & Kelly, J. W. (2002) Nat. Rev. Drug Discovery 1, 267-275.
48. Bennett, M. J., Huey-Tubman, K. E., Herr, A. B., West, A. P., Jr., Ross, S., A. & Bjorkman, P. J. (2002) Proc. Natl. Acad. Sci. USA 99, 11634- 11639.