-
1
-
-
0022640843
-
Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins
-
Mosmann TR, Cherwinski H, Bond MW, Giedlin MA, Coffman RL. Two types of murine helper T cell clone. I. Definition according to profiles of lymphokine activities and secreted proteins. J Immunol 1986; 136:2348-57.
-
(1986)
J Immunol
, vol.136
, pp. 2348-2357
-
-
Mosmann, T.R.1
Cherwinski, H.2
Bond, M.W.3
Giedlin, M.A.4
Coffman, R.L.5
-
3
-
-
56349154943
-
Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset
-
Veldhoen M, Uyttenhove C, van Snick J et al. Transforming growth factor-beta 'reprograms' the differentiation of T helper 2 cells and promotes an interleukin 9-producing subset. Nat Immunol 2008; 9:1341-6.
-
(2008)
Nat Immunol
, vol.9
, pp. 1341-1346
-
-
Veldhoen, M.1
Uyttenhove, C.2
van Snick, J.3
-
4
-
-
77954948735
-
Effector T cell plasticity: flexibility in the face of changing circumstances
-
Murphy KM, Stockinger B. Effector T cell plasticity: flexibility in the face of changing circumstances. Nat Immunol 2011; 11:674-80.
-
(2011)
Nat Immunol
, vol.11
, pp. 674-680
-
-
Murphy, K.M.1
Stockinger, B.2
-
6
-
-
78149326083
-
H2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma
-
H2 memory/effector cells that produce inflammatory IL-17 cytokine and promote the exacerbation of chronic allergic asthma. J Exp Med 2010; 207:2479-91.
-
(2010)
J Exp Med
, vol.207
, pp. 2479-2491
-
-
Wang, Y.H.1
Voo, K.S.2
Liu, B.3
-
8
-
-
0023913458
-
+ T cells in the IgE response and immunity to Nippostrongylus brasiliensis
-
+ T cells in the IgE response and immunity to Nippostrongylus brasiliensis. J Immunol 1988; 140:3206-11.
-
(1988)
J Immunol
, vol.140
, pp. 3206-3211
-
-
Katona, I.M.1
Urban Jr, J.F.2
Finkelman, F.D.3
-
11
-
-
0034162535
-
Stat6 regulation of in vivo IL-4 responses
-
Finkelman FD, Morris SC, Orekhova T et al. Stat6 regulation of in vivo IL-4 responses. J Immunol 2000; 164:2303-10.
-
(2000)
J Immunol
, vol.164
, pp. 2303-2310
-
-
Finkelman, F.D.1
Morris, S.C.2
Orekhova, T.3
-
13
-
-
8644220507
-
Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: a target for STAT6 but not GATA3
-
Lee DU, Rao A. Molecular analysis of a locus control region in the T helper 2 cytokine gene cluster: a target for STAT6 but not GATA3. Proc Natl Acad Sci U S A 2004; 101:16010-5.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 16010-16015
-
-
Lee, D.U.1
Rao, A.2
-
15
-
-
25144476332
-
+ T cells to generate a Th2-inducing cytokine environment
-
+ T cells to generate a Th2-inducing cytokine environment. J Exp Med 2005; 202:793-804.
-
(2005)
J Exp Med
, vol.202
, pp. 793-804
-
-
Yamane, H.1
Zhu, J.2
Paul, W.E.3
-
16
-
-
4344647601
-
Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite
-
Min B, Prout M, Hu-Li J et al. Basophils produce IL-4 and accumulate in tissues after infection with a Th2-inducing parasite. J Exp Med 2004; 200:507-17.
-
(2004)
J Exp Med
, vol.200
, pp. 507-517
-
-
Min, B.1
Prout, M.2
Hu-Li, J.3
-
17
-
-
39449133957
-
A mechanism for the initiation of allergen-induced T helper type 2 responses
-
Sokol CL, Barton GM, Farr AG, Medzhitov R. A mechanism for the initiation of allergen-induced T helper type 2 responses. Nat Immunol 2008; 9:310-8.
-
(2008)
Nat Immunol
, vol.9
, pp. 310-318
-
-
Sokol, C.L.1
Barton, G.M.2
Farr, A.G.3
Medzhitov, R.4
-
18
-
-
79952741741
-
Basophils are the major producers of IL-4 during primary helminth infection
-
van Panhuys N, Prout M, Forbes E, Min B, Paul WE, Le Gros G. Basophils are the major producers of IL-4 during primary helminth infection. J Immunol 2011; 186:2719-28.
-
(2011)
J Immunol
, vol.186
, pp. 2719-2728
-
-
van Panhuys, N.1
Prout, M.2
Forbes, E.3
Min, B.4
Paul, W.E.5
Le Gros, G.6
-
20
-
-
67649216604
-
Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response
-
Sokol CL, Chu NQ, Yu S, Nish SA, Laufer TM, Medzhitov R. Basophils function as antigen-presenting cells for an allergen-induced T helper type 2 response. Nat Immunol 2009; 10:713-20.
-
(2009)
Nat Immunol
, vol.10
, pp. 713-720
-
-
Sokol, C.L.1
Chu, N.Q.2
Yu, S.3
Nish, S.A.4
Laufer, T.M.5
Medzhitov, R.6
-
22
-
-
63449108301
-
Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity
-
Ohnmacht C, Pullner A, King SB, Drexler I, Meier S, Brocker T, Voehringer D. Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity. J Exp Med 2009; 206:549-59.
-
(2009)
J Exp Med
, vol.206
, pp. 549-559
-
-
Ohnmacht, C.1
Pullner, A.2
King, S.B.3
Drexler, I.4
Meier, S.5
Brocker, T.6
Voehringer, D.7
-
23
-
-
77957020655
-
Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths
-
Ohnmacht C, Schwartz C, Panzer M, Schiedewitz I, Naumann R, Voehringer D. Basophils orchestrate chronic allergic dermatitis and protective immunity against helminths. Immunity 2010; 33:364-74.
-
(2010)
Immunity
, vol.33
, pp. 364-374
-
-
Ohnmacht, C.1
Schwartz, C.2
Panzer, M.3
Schiedewitz, I.4
Naumann, R.5
Voehringer, D.6
-
24
-
-
77957731193
-
CD11c depletion severely disrupts Th2 induction and development in vivo
-
Phythian-Adams AT, Cook PC, Lundie RJ et al. CD11c depletion severely disrupts Th2 induction and development in vivo. J Exp Med 2010; 207:2089-96.
-
(2010)
J Exp Med
, vol.207
, pp. 2089-2096
-
-
Phythian-Adams, A.T.1
Cook, P.C.2
Lundie, R.J.3
-
25
-
-
77957745031
-
Inflammatory dendritic cells - not basophils - are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen
-
Hammad H, Plantinga M, Deswarte K, Pouliot P, Willart MA, Kool M, Muskens F, Lambrecht BN. Inflammatory dendritic cells - not basophils - are necessary and sufficient for induction of Th2 immunity to inhaled house dust mite allergen. J Exp Med 2010; 207:2097-111.
-
(2010)
J Exp Med
, vol.207
, pp. 2097-2111
-
-
Hammad, H.1
Plantinga, M.2
Deswarte, K.3
Pouliot, P.4
Willart, M.A.5
Kool, M.6
Muskens, F.7
Lambrecht, B.N.8
-
26
-
-
79956158089
-
Genetic analysis of basophil function in vivo
-
Sullivan BM, Liang HE, Bando JK, Wu D, Cheng LE, McKerrow JK, Allen CD, Locksley RM. Genetic analysis of basophil function in vivo. Nat Immunol 2011; 12:527-35.
-
(2011)
Nat Immunol
, vol.12
, pp. 527-535
-
-
Sullivan, B.M.1
Liang, H.E.2
Bando, J.K.3
Wu, D.4
Cheng, L.E.5
McKerrow, J.K.6
Allen, C.D.7
Locksley, R.M.8
-
27
-
-
77953812779
-
The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling
-
Tang H, Cao W, Kasturi SP et al. The T helper type 2 response to cysteine proteases requires dendritic cell-basophil cooperation via ROS-mediated signaling. Nat Immunol 2010; 11:608-17.
-
(2010)
Nat Immunol
, vol.11
, pp. 608-617
-
-
Tang, H.1
Cao, W.2
Kasturi, S.P.3
-
29
-
-
0034600567
-
Inducible costimulator protein (ICOS) controls T helper cell subset polarization after virus and parasite infection
-
Kopf M, Coyle AJ, Schmitz N, Barner M, Oxenius A, Gallimore A, Gutierrez-Ramos JC, Bachmann MF. Inducible costimulator protein (ICOS) controls T helper cell subset polarization after virus and parasite infection. J Exp Med 2000; 192:53-61.
-
(2000)
J Exp Med
, vol.192
, pp. 53-61
-
-
Kopf, M.1
Coyle, A.J.2
Schmitz, N.3
Barner, M.4
Oxenius, A.5
Gallimore, A.6
Gutierrez-Ramos, J.C.7
Bachmann, M.F.8
-
30
-
-
0028867420
-
Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4
-
Tivol EA, Borriello F, Schweitzer AN, Lynch WP, Bluestone JA, Sharpe AH. Loss of CTLA-4 leads to massive lymphoproliferation and fatal multiorgan tissue destruction, revealing a critical negative regulatory role of CTLA-4. Immunity 1995; 3:541-7.
-
(1995)
Immunity
, vol.3
, pp. 541-547
-
-
Tivol, E.A.1
Borriello, F.2
Schweitzer, A.N.3
Lynch, W.P.4
Bluestone, J.A.5
Sharpe, A.H.6
-
31
-
-
0033198045
-
The role of CTLA-4 in regulating Th2 differentiation
-
Oosterwegel MA, Mandelbrot DA, Boyd SD, Lorsbach RB, Jarrett DY, Abbas AK, Sharpe AH. The role of CTLA-4 in regulating Th2 differentiation. J Immunol 1999; 163:2634-9.
-
(1999)
J Immunol
, vol.163
, pp. 2634-2639
-
-
Oosterwegel, M.A.1
Mandelbrot, D.A.2
Boyd, S.D.3
Lorsbach, R.B.4
Jarrett, D.Y.5
Abbas, A.K.6
Sharpe, A.H.7
-
32
-
-
0141925700
-
CTLA-4 engagement inhibits Th2 but not Th1 cell polarisation
-
Ubaldi V, Gatta L, Pace L, Doria G, Pioli C. CTLA-4 engagement inhibits Th2 but not Th1 cell polarisation. Clin Dev Immunol 2003; 10:13-7.
-
(2003)
Clin Dev Immunol
, vol.10
, pp. 13-17
-
-
Ubaldi, V.1
Gatta, L.2
Pace, L.3
Doria, G.4
Pioli, C.5
-
33
-
-
0033563265
-
Lymphoproliferative disorder in CTLA-4 knockout mice is characterized by CD28-regulated activation of Th2 responses
-
Khattri R, Auger JA, Griffin MD, Sharpe AH, Bluestone JA. Lymphoproliferative disorder in CTLA-4 knockout mice is characterized by CD28-regulated activation of Th2 responses. J Immunol 1999; 162:5784-91.
-
(1999)
J Immunol
, vol.162
, pp. 5784-5791
-
-
Khattri, R.1
Auger, J.A.2
Griffin, M.D.3
Sharpe, A.H.4
Bluestone, J.A.5
-
36
-
-
85047692516
-
Signalling pathways of the TNF superfamily: a double-edged sword
-
Aggarwal BB. Signalling pathways of the TNF superfamily: a double-edged sword. Nat Rev Immunol 2003; 3:745-56.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 745-756
-
-
Aggarwal, B.B.1
-
37
-
-
35748935554
-
Dendritic cell expression of OX40 ligand acts as a costimulatory, not polarizing, signal for optimal Th2 priming and memory induction in vivo
-
Jenkins SJ, Perona-Wright G, Worsley AG, Ishii N, MacDonald AS. Dendritic cell expression of OX40 ligand acts as a costimulatory, not polarizing, signal for optimal Th2 priming and memory induction in vivo. J Immunol 2007; 179:3515-23.
-
(2007)
J Immunol
, vol.179
, pp. 3515-3523
-
-
Jenkins, S.J.1
Perona-Wright, G.2
Worsley, A.G.3
Ishii, N.4
MacDonald, A.S.5
-
38
-
-
80051623629
-
Th2 responses to helminth parasites can be therapeutically enhanced by, but are not dependent upon, GITR-GITR ligand costimulation in vivo
-
van der Werf N, Redpath SA, Phythian-Adams AT, Azuma M, Allen JE, Maizels RM, Macdonald AS, Taylor MD. Th2 responses to helminth parasites can be therapeutically enhanced by, but are not dependent upon, GITR-GITR ligand costimulation in vivo. J Immunol 2011; 187:1411-20.
-
(2011)
J Immunol
, vol.187
, pp. 1411-1420
-
-
van der Werf, N.1
Redpath, S.A.2
Phythian-Adams, A.T.3
Azuma, M.4
Allen, J.E.5
Maizels, R.M.6
Macdonald, A.S.7
Taylor, M.D.8
-
39
-
-
73949084268
-
GITR signaling potentiates airway hyperresponsiveness by enhancing Th2 cell activity in a mouse model of asthma
-
Motta AC, Vissers JL, Gras R, Van Esch BC, Van Oosterhout AJ, Nawijn MC. GITR signaling potentiates airway hyperresponsiveness by enhancing Th2 cell activity in a mouse model of asthma. Respir Res 2009; 10:93.
-
(2009)
Respir Res
, vol.10
, pp. 93
-
-
Motta, A.C.1
Vissers, J.L.2
Gras, R.3
Van Esch, B.C.4
Van Oosterhout, A.J.5
Nawijn, M.C.6
-
40
-
-
29744441207
-
Glucocorticoid-induced TNFR family-related protein (GITR) activation exacerbates murine asthma and collagen-induced arthritis
-
Patel M, Xu D, Kewin P, Choo-Kang B, McSharry C, Thomson NC, Liew FY. Glucocorticoid-induced TNFR family-related protein (GITR) activation exacerbates murine asthma and collagen-induced arthritis. Eur J Immunol 2005; 35:3581-90.
-
(2005)
Eur J Immunol
, vol.35
, pp. 3581-3590
-
-
Patel, M.1
Xu, D.2
Kewin, P.3
Choo-Kang, B.4
McSharry, C.5
Thomson, N.C.6
Liew, F.Y.7
-
41
-
-
34447634411
-
Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch
-
Amsen D, Antov A, Jankovic D et al. Direct regulation of Gata3 expression determines the T helper differentiation potential of Notch. Immunity 2007; 27:89-99.
-
(2007)
Immunity
, vol.27
, pp. 89-99
-
-
Amsen, D.1
Antov, A.2
Jankovic, D.3
-
42
-
-
34447642439
-
Notch directly regulates Gata3 expression during T helper 2 cell differentiation
-
Fang TC, Yashiro-Ohtani Y, Del Bianco C, Knoblock DM, Blacklow SC, Pear WS. Notch directly regulates Gata3 expression during T helper 2 cell differentiation. Immunity 2007; 27:100-10.
-
(2007)
Immunity
, vol.27
, pp. 100-110
-
-
Fang, T.C.1
Yashiro-Ohtani, Y.2
Del Bianco, C.3
Knoblock, D.M.4
Blacklow, S.C.5
Pear, W.S.6
-
43
-
-
44849088491
-
Dendritic cell expression of the Notch ligand jagged2 is not essential for Th2 response induction in vivo
-
Worsley AG, LeibundGut-Landmann S, Slack E, Phng LK, Gerhardt H, Reis e Sousa C, MacDonald AS. Dendritic cell expression of the Notch ligand jagged2 is not essential for Th2 response induction in vivo. Eur J Immunol 2008; 38:1043-9.
-
(2008)
Eur J Immunol
, vol.38
, pp. 1043-1049
-
-
Worsley, A.G.1
LeibundGut-Landmann, S.2
Slack, E.3
Phng, L.K.4
Gerhardt, H.5
Reis e Sousa, C.6
MacDonald, A.S.7
-
44
-
-
41449093693
-
Human immature myeloid dendritic cells trigger a TH2-polarizing program via Jagged-1/Notch interaction
-
Liotta F, Frosali F, Querci V et al. Human immature myeloid dendritic cells trigger a TH2-polarizing program via Jagged-1/Notch interaction. J Allergy Clin Immunol 2008; 121:1000-5.
-
(2008)
J Allergy Clin Immunol
, vol.121
, pp. 1000-1005
-
-
Liotta, F.1
Frosali, F.2
Querci, V.3
-
45
-
-
78650642332
-
Notch ligand delta-like 4 regulates development and pathogenesis of allergic airway responses by modulating IL-2 production and Th2 immunity
-
Jang S, Schaller M, Berlin AA, Lukacs NW. Notch ligand delta-like 4 regulates development and pathogenesis of allergic airway responses by modulating IL-2 production and Th2 immunity. J Immunol 2010; 185:5835-44.
-
(2010)
J Immunol
, vol.185
, pp. 5835-5844
-
-
Jang, S.1
Schaller, M.2
Berlin, A.A.3
Lukacs, N.W.4
-
46
-
-
36549001590
-
Notch ligand Delta-like 4 regulates disease pathogenesis during respiratory viral infections by modulating Th2 cytokines
-
Schaller MA, Neupane R, Rudd BD et al. Notch ligand Delta-like 4 regulates disease pathogenesis during respiratory viral infections by modulating Th2 cytokines. J Exp Med 2007; 204:2925-34.
-
(2007)
J Exp Med
, vol.204
, pp. 2925-2934
-
-
Schaller, M.A.1
Neupane, R.2
Rudd, B.D.3
-
47
-
-
40749089559
-
Suppression of Th2 cell development by Notch ligands Delta1 and Delta4
-
Sun J, Krawczyk CJ, Pearce EJ. Suppression of Th2 cell development by Notch ligands Delta1 and Delta4. J Immunol 2008; 180:1655-61.
-
(2008)
J Immunol
, vol.180
, pp. 1655-1661
-
-
Sun, J.1
Krawczyk, C.J.2
Pearce, E.J.3
-
48
-
-
1642398043
-
Interleukin 2 plays a central role in Th2 differentiation
-
Cote-Sierra J, Foucras G, Guo L, Chiodetti L, Young HA, Hu-Li J, Zhu J, Paul WE. Interleukin 2 plays a central role in Th2 differentiation. Proc Natl Acad Sci U S A 2004; 101:3880-5.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 3880-3885
-
-
Cote-Sierra, J.1
Foucras, G.2
Guo, L.3
Chiodetti, L.4
Young, H.A.5
Hu-Li, J.6
Zhu, J.7
Paul, W.E.8
-
49
-
-
0030810155
-
The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells
-
Zheng W, Flavell RA. The transcription factor GATA-3 is necessary and sufficient for Th2 cytokine gene expression in CD4 T cells. Cell 1997; 89:587-96.
-
(1997)
Cell
, vol.89
, pp. 587-596
-
-
Zheng, W.1
Flavell, R.A.2
-
50
-
-
1242274405
-
GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells
-
Pai SY, Truitt ML, Ho IC. GATA-3 deficiency abrogates the development and maintenance of T helper type 2 cells. Proc Natl Acad Sci U S A 2004; 101:1993-8.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 1993-1998
-
-
Pai, S.Y.1
Truitt, M.L.2
Ho, I.C.3
-
51
-
-
33646196946
-
Regulation of Th2 differentiation and Il4 locus accessibility
-
Ansel KM, Djuretic I, Tanasa B, Rao A. Regulation of Th2 differentiation and Il4 locus accessibility. Annu Rev Immunol 2006; 24:607-56.
-
(2006)
Annu Rev Immunol
, vol.24
, pp. 607-656
-
-
Ansel, K.M.1
Djuretic, I.2
Tanasa, B.3
Rao, A.4
-
52
-
-
79960035010
-
An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiation
-
Yagi R, Zhu J, Paul WE. An updated view on transcription factor GATA3-mediated regulation of Th1 and Th2 cell differentiation. Int Immunol 2011; 23:415-20.
-
(2011)
Int Immunol
, vol.23
, pp. 415-420
-
-
Yagi, R.1
Zhu, J.2
Paul, W.E.3
-
53
-
-
0028177589
-
CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3
-
Yoshimoto T, Paul WE. CD4pos, NK1.1pos T cells promptly produce interleukin 4 in response to in vivo challenge with anti-CD3. J Exp Med 1994; 179:1285-95.
-
(1994)
J Exp Med
, vol.179
, pp. 1285-1295
-
-
Yoshimoto, T.1
Paul, W.E.2
-
54
-
-
0025753325
-
Mouse splenic and bone marrow cell populations that express high-affinity Fc epsilon receptors and produce interleukin 4 are highly enriched in basophils
-
Seder RA, Paul WE, Dvorak AM et al. Mouse splenic and bone marrow cell populations that express high-affinity Fc epsilon receptors and produce interleukin 4 are highly enriched in basophils. Proc Natl Acad Sci U S A 1991; 88:2835-9.
-
(1991)
Proc Natl Acad Sci U S A
, vol.88
, pp. 2835-2839
-
-
Seder, R.A.1
Paul, W.E.2
Dvorak, A.M.3
-
55
-
-
77249158040
-
Cutting edge: basophils are transiently recruited into the draining lymph nodes during helminth infection via IL-3, but infection-induced Th2 immunity can develop without basophil lymph node recruitment or IL-3
-
Kim S, Prout M, Ramshaw H, Lopez AF, LeGros G, Min B. Cutting edge: basophils are transiently recruited into the draining lymph nodes during helminth infection via IL-3, but infection-induced Th2 immunity can develop without basophil lymph node recruitment or IL-3. J Immunol 2010; 184:1143-7.
-
(2010)
J Immunol
, vol.184
, pp. 1143-1147
-
-
Kim, S.1
Prout, M.2
Ramshaw, H.3
Lopez, A.F.4
LeGros, G.5
Min, B.6
-
56
-
-
50449101434
-
In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation
-
van Panhuys N, Tang SC, Prout M et al. In vivo studies fail to reveal a role for IL-4 or STAT6 signaling in Th2 lymphocyte differentiation. Proc Natl Acad Sci U S A 2008; 105:12423-8.
-
(2008)
Proc Natl Acad Sci U S A
, vol.105
, pp. 12423-12428
-
-
van Panhuys, N.1
Tang, S.C.2
Prout, M.3
-
57
-
-
0036301998
-
Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP
-
Soumelis V, Reche PA, Kanzler H et al. Human epithelial cells trigger dendritic cell mediated allergic inflammation by producing TSLP. Nat Immunol 2002; 3:673-80.
-
(2002)
Nat Immunol
, vol.3
, pp. 673-680
-
-
Soumelis, V.1
Reche, P.A.2
Kanzler, H.3
-
58
-
-
79955143880
-
Thymic stromal lymphopoietin is expressed and produced by caspase-1/NF-kappaB pathway in mast cells
-
Moon PD, Kim HM. Thymic stromal lymphopoietin is expressed and produced by caspase-1/NF-kappaB pathway in mast cells. Cytokine 2011; 54:239-43.
-
(2011)
Cytokine
, vol.54
, pp. 239-243
-
-
Moon, P.D.1
Kim, H.M.2
-
59
-
-
80051636834
-
Thymic stromal lymphopoietin is produced by dendritic cells
-
Kashyap M, Rochman Y, Spolski R, Samsel L, Leonard WJ. Thymic stromal lymphopoietin is produced by dendritic cells. J Immunol 2011; 187:1207-11.
-
(2011)
J Immunol
, vol.187
, pp. 1207-1211
-
-
Kashyap, M.1
Rochman, Y.2
Spolski, R.3
Samsel, L.4
Leonard, W.J.5
-
60
-
-
25844515028
-
Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice
-
Zhou B, Comeau MR, De Smedt T et al. Thymic stromal lymphopoietin as a key initiator of allergic airway inflammation in mice. Nat Immunol 2005; 6:1047-53.
-
(2005)
Nat Immunol
, vol.6
, pp. 1047-1053
-
-
Zhou, B.1
Comeau, M.R.2
De Smedt, T.3
-
61
-
-
34548713042
-
TLR3- and Th2 cytokine-dependent production of thymic stromal lymphopoietin in human airway epithelial cells
-
Kato A, Favoreto S Jr, Avila PC, Schleimer RP. TLR3- and Th2 cytokine-dependent production of thymic stromal lymphopoietin in human airway epithelial cells. J Immunol 2007; 179:1080-7.
-
(2007)
J Immunol
, vol.179
, pp. 1080-1087
-
-
Kato, A.1
Favoreto Jr, S.2
Avila, P.C.3
Schleimer, R.P.4
-
62
-
-
27744510433
-
TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand
-
Ito T, Wang YH, Duramad O et al. TSLP-activated dendritic cells induce an inflammatory T helper type 2 cell response through OX40 ligand. J Exp Med 2005; 202:1213-23.
-
(2005)
J Exp Med
, vol.202
, pp. 1213-1223
-
-
Ito, T.1
Wang, Y.H.2
Duramad, O.3
-
63
-
-
3242757478
-
+ T cell development
-
+ T cell development. J Exp Med 2004; 200:159-68.
-
(2004)
J Exp Med
, vol.200
, pp. 159-168
-
-
Al-Shami, A.1
Spolski, R.2
Kelly, J.3
Fry, T.4
Schwartzberg, P.L.5
Pandey, A.6
Mackall, C.L.7
Leonard, W.J.8
-
64
-
-
25144525707
-
A role for TSLP in the development of inflammation in an asthma model
-
Al-Shami A, Spolski R, Kelly J, Keane-Myers A, Leonard WJ. A role for TSLP in the development of inflammation in an asthma model. J Exp Med 2005; 202:829-39.
-
(2005)
J Exp Med
, vol.202
, pp. 829-839
-
-
Al-Shami, A.1
Spolski, R.2
Kelly, J.3
Keane-Myers, A.4
Leonard, W.J.5
-
65
-
-
69549135695
-
Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function
-
Massacand JC, Stettler RC, Meier R, Humphreys NE, Grencis RK, Marsland BJ, Harris NL. Helminth products bypass the need for TSLP in Th2 immune responses by directly modulating dendritic cell function. Proc Natl Acad Sci U S A 2009; 106:13968-73.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 13968-13973
-
-
Massacand, J.C.1
Stettler, R.C.2
Meier, R.3
Humphreys, N.E.4
Grencis, R.K.5
Marsland, B.J.6
Harris, N.L.7
-
66
-
-
69549086000
-
Regulation of helminth-induced Th2 responses by thymic stromal lymphopoietin
-
Ramalingam TR, Pesce JT, Mentink-Kane MM, Madala S, Cheever AW, Comeau MR, Ziegler SF, Wynn TA. Regulation of helminth-induced Th2 responses by thymic stromal lymphopoietin. J Immunol 2009; 182:6452-9.
-
(2009)
J Immunol
, vol.182
, pp. 6452-6459
-
-
Ramalingam, T.R.1
Pesce, J.T.2
Mentink-Kane, M.M.3
Madala, S.4
Cheever, A.W.5
Comeau, M.R.6
Ziegler, S.F.7
Wynn, T.A.8
-
67
-
-
79957609041
-
Diversity and dialogue in immunity to helminths
-
Allen JE, Maizels RM. Diversity and dialogue in immunity to helminths. Nat Rev Immunol 2011; 11:375-88.
-
(2011)
Nat Rev Immunol
, vol.11
, pp. 375-388
-
-
Allen, J.E.1
Maizels, R.M.2
-
68
-
-
66149113689
-
Thymic stromal lymphopoietin, OX40-ligand, and interleukin-25 in allergic responses
-
Wang YH, Liu YJ. Thymic stromal lymphopoietin, OX40-ligand, and interleukin-25 in allergic responses. Clin Exp Allergy 2009; 39:798-806.
-
(2009)
Clin Exp Allergy
, vol.39
, pp. 798-806
-
-
Wang, Y.H.1
Liu, Y.J.2
-
69
-
-
77956404942
-
Protease allergens induce the expression of IL-25 via Erk and p38 MAPK pathway
-
Yu HS, Angkasekwinai P, Chang SH, Chung Y, Dong C. Protease allergens induce the expression of IL-25 via Erk and p38 MAPK pathway. J Korean Med Sci 2010; 25:829-34.
-
(2010)
J Korean Med Sci
, vol.25
, pp. 829-834
-
-
Yu, H.S.1
Angkasekwinai, P.2
Chang, S.H.3
Chung, Y.4
Dong, C.5
-
70
-
-
34447281733
-
Interleukin 25 promotes the initiation of proallergic type 2 responses
-
Angkasekwinai P, Park H, Wang YH, Chang SH, Corry DB, Liu YJ, Zhu Z, Dong C. Interleukin 25 promotes the initiation of proallergic type 2 responses. J Exp Med 2007; 204:1509-17.
-
(2007)
J Exp Med
, vol.204
, pp. 1509-1517
-
-
Angkasekwinai, P.1
Park, H.2
Wang, Y.H.3
Chang, S.H.4
Corry, D.B.5
Liu, Y.J.6
Zhu, Z.7
Dong, C.8
-
71
-
-
33645888708
-
Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion
-
Fallon PG, Ballantyne SJ, Mangan NE et al. Identification of an interleukin (IL)-25-dependent cell population that provides IL-4, IL-5, and IL-13 at the onset of helminth expulsion. J Exp Med 2006; 203:1105-16.
-
(2006)
J Exp Med
, vol.203
, pp. 1105-1116
-
-
Fallon, P.G.1
Ballantyne, S.J.2
Mangan, N.E.3
-
72
-
-
33645896155
-
Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract
-
Owyang AM, Zaph C, Wilson EH et al. Interleukin 25 regulates type 2 cytokine-dependent immunity and limits chronic inflammation in the gastrointestinal tract. J Exp Med 2006; 203:843-9.
-
(2006)
J Exp Med
, vol.203
, pp. 843-849
-
-
Owyang, A.M.1
Zaph, C.2
Wilson, E.H.3
-
73
-
-
18244405108
-
IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo
-
Fort MM, Cheung J, Yen D et al. IL-25 induces IL-4, IL-5, and IL-13 and Th2-associated pathologies in vivo. Immunity 2001; 15:985-95.
-
(2001)
Immunity
, vol.15
, pp. 985-995
-
-
Fort, M.M.1
Cheung, J.2
Yen, D.3
-
74
-
-
34547820890
-
IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells
-
Wang YH, Angkasekwinai P, Lu N et al. IL-25 augments type 2 immune responses by enhancing the expansion and functions of TSLP-DC-activated Th2 memory cells. J Exp Med 2007; 204:1837-47.
-
(2007)
J Exp Med
, vol.204
, pp. 1837-1847
-
-
Wang, Y.H.1
Angkasekwinai, P.2
Lu, N.3
-
75
-
-
77951817855
-
Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity
-
Neill DR, Wong SH, Bellosi A et al. Nuocytes represent a new innate effector leukocyte that mediates type-2 immunity. Nature 2010; 464:1367-70.
-
(2010)
Nature
, vol.464
, pp. 1367-1370
-
-
Neill, D.R.1
Wong, S.H.2
Bellosi, A.3
-
78
-
-
76949102494
-
Regulation of IL-9 expression by IL-25 signaling
-
Angkasekwinai P, Chang SH, Thapa M, Watarai H, Dong C. Regulation of IL-9 expression by IL-25 signaling. Nat Immunol 2010; 11:250-6.
-
(2010)
Nat Immunol
, vol.11
, pp. 250-256
-
-
Angkasekwinai, P.1
Chang, S.H.2
Thapa, M.3
Watarai, H.4
Dong, C.5
-
79
-
-
78650642300
-
Critical role of IL-25 in nematode infection-induced alterations in intestinal function
-
Zhao A, Urban JF Jr, Sun R et al. Critical role of IL-25 in nematode infection-induced alterations in intestinal function. J Immunol 2010; 185:6921-9.
-
(2010)
J Immunol
, vol.185
, pp. 6921-6929
-
-
Zhao, A.1
Urban Jr, J.F.2
Sun, R.3
-
80
-
-
79955082903
-
Nuocytes and beyond: new insights into helminth expulsion
-
Neill DR, McKenzie AN. Nuocytes and beyond: new insights into helminth expulsion. Trends Parasitol 2011; 27:214-21.
-
(2011)
Trends Parasitol
, vol.27
, pp. 214-221
-
-
Neill, D.R.1
McKenzie, A.N.2
-
81
-
-
79952531912
-
Type 2 innate immune responses and the natural helper cell
-
Koyasu S, Moro K. Type 2 innate immune responses and the natural helper cell. Immunology 2011; 132:475-81.
-
(2011)
Immunology
, vol.132
, pp. 475-481
-
-
Koyasu, S.1
Moro, K.2
-
82
-
-
44849117539
-
Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system
-
Kondo Y, Yoshimoto T, Yasuda K et al. Administration of IL-33 induces airway hyperresponsiveness and goblet cell hyperplasia in the lungs in the absence of adaptive immune system. Int Immunol 2008; 20:791-800.
-
(2008)
Int Immunol
, vol.20
, pp. 791-800
-
-
Kondo, Y.1
Yoshimoto, T.2
Yasuda, K.3
-
83
-
-
58149300244
-
+ T cells and promotes allergic-induced airway inflammation independent of IL-4
-
+ T cells and promotes allergic-induced airway inflammation independent of IL-4. J Immunol 2008; 181:4780-90.
-
(2008)
J Immunol
, vol.181
, pp. 4780-4790
-
-
Kurowska-Stolarska, M.1
Kewin, P.2
Murphy, G.3
-
84
-
-
27744446058
-
IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
-
Schmitz J, Owyang A, Oldham E et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity 2005; 23:479-90.
-
(2005)
Immunity
, vol.23
, pp. 479-490
-
-
Schmitz, J.1
Owyang, A.2
Oldham, E.3
-
85
-
-
37249049230
-
IL-33 induces IL-13 production by mouse mast cells independently of IgE-FcepsilonRI signals
-
Ho LH, Ohno T, Oboki K et al. IL-33 induces IL-13 production by mouse mast cells independently of IgE-FcepsilonRI signals. J Leukoc Biol 2007; 82:1481-90.
-
(2007)
J Leukoc Biol
, vol.82
, pp. 1481-1490
-
-
Ho, L.H.1
Ohno, T.2
Oboki, K.3
-
86
-
-
70049104738
-
IL-18 and IL-33 elicit Th2 cytokines from basophils via a MyD88- and p38alpha-dependent pathway
-
Kroeger KM, Sullivan BM, Locksley RM. IL-18 and IL-33 elicit Th2 cytokines from basophils via a MyD88- and p38alpha-dependent pathway. J Leukoc Biol 2009; 86:769-78.
-
(2009)
J Leukoc Biol
, vol.86
, pp. 769-778
-
-
Kroeger, K.M.1
Sullivan, B.M.2
Locksley, R.M.3
-
87
-
-
70349337464
-
IL-33 activates unprimed murine basophils directly in vitro and induces their in vivo expansion indirectly by promoting hematopoietic growth factor production
-
Schneider E, Petit-Bertron AF, Bricard R, Levasseur M, Ramadan A, Girard JP, Herbelin A, Dy M. IL-33 activates unprimed murine basophils directly in vitro and induces their in vivo expansion indirectly by promoting hematopoietic growth factor production. J Immunol 2009; 183:3591-7.
-
(2009)
J Immunol
, vol.183
, pp. 3591-3597
-
-
Schneider, E.1
Petit-Bertron, A.F.2
Bricard, R.3
Levasseur, M.4
Ramadan, A.5
Girard, J.P.6
Herbelin, A.7
Dy, M.8
-
88
-
-
35348850153
-
IL-33 is a chemoattractant for human Th2 cells
-
Komai-Koma M, Xu D, Li Y, McKenzie AN, McInnes IB, Liew FY. IL-33 is a chemoattractant for human Th2 cells. Eur J Immunol 2007; 37:2779-86.
-
(2007)
Eur J Immunol
, vol.37
, pp. 2779-2786
-
-
Komai-Koma, M.1
Xu, D.2
Li, Y.3
McKenzie, A.N.4
McInnes, I.B.5
Liew, F.Y.6
-
89
-
-
69449106110
-
IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells
-
Guo L, Wei G, Zhu J, Liao W, Leonard WJ, Zhao K, Paul W. IL-1 family members and STAT activators induce cytokine production by Th2, Th17, and Th1 cells. Proc Natl Acad Sci U S A 2009; 106:13463-8.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 13463-13468
-
-
Guo, L.1
Wei, G.2
Zhu, J.3
Liao, W.4
Leonard, W.J.5
Zhao, K.6
Paul, W.7
-
90
-
-
0033523665
-
Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses
-
Coyle AJ, Lloyd C, Tian J et al. Crucial role of the interleukin 1 receptor family member T1/ST2 in T helper cell type 2-mediated lung mucosal immune responses. J Exp Med 1999; 190:895-902.
-
(1999)
J Exp Med
, vol.190
, pp. 895-902
-
-
Coyle, A.J.1
Lloyd, C.2
Tian, J.3
-
91
-
-
0037378857
-
Signaling through the T1/ST2 molecule is not necessary for Th2 differentiation but is important for the regulation of type 1 responses in nonhealing Leishmania major infection
-
Kropf P, Herath S, Klemenz R, Muller I. Signaling through the T1/ST2 molecule is not necessary for Th2 differentiation but is important for the regulation of type 1 responses in nonhealing Leishmania major infection. Infect Immun 2003; 71:1961-71.
-
(2003)
Infect Immun
, vol.71
, pp. 1961-1971
-
-
Kropf, P.1
Herath, S.2
Klemenz, R.3
Muller, I.4
-
92
-
-
0034689033
-
T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses
-
Townsend MJ, Fallon PG, Matthews DJ, Jolin HE, McKenzie AN. T1/ST2-deficient mice demonstrate the importance of T1/ST2 in developing primary T helper cell type 2 responses. J Exp Med 2000; 191:1069-76.
-
(2000)
J Exp Med
, vol.191
, pp. 1069-1076
-
-
Townsend, M.J.1
Fallon, P.G.2
Matthews, D.J.3
Jolin, H.E.4
McKenzie, A.N.5
-
93
-
-
0033570791
-
The absence of interleukin 1 receptor-related T1/ST2 does not affect T helper cell type 2 development and its effector function
-
Hoshino K, Kashiwamura S, Kuribayashi K et al. The absence of interleukin 1 receptor-related T1/ST2 does not affect T helper cell type 2 development and its effector function. J Exp Med 1999; 190:1541-8.
-
(1999)
J Exp Med
, vol.190
, pp. 1541-1548
-
-
Hoshino, K.1
Kashiwamura, S.2
Kuribayashi, K.3
-
94
-
-
79955509396
-
Endogenous IL-33 enhances Th2 cytokine production and T-cell responses during allergic airway inflammation
-
Louten J, Rankin AL, Li Y et al. Endogenous IL-33 enhances Th2 cytokine production and T-cell responses during allergic airway inflammation. Int Immunol 2011; 23:307-15.
-
(2011)
Int Immunol
, vol.23
, pp. 307-315
-
-
Louten, J.1
Rankin, A.L.2
Li, Y.3
-
95
-
-
14044257261
-
Variegation of the immune response with dendritic cells and pathogen recognition receptors
-
Pulendran B. Variegation of the immune response with dendritic cells and pathogen recognition receptors. J Immunol 2005; 174:2457-65.
-
(2005)
J Immunol
, vol.174
, pp. 2457-2465
-
-
Pulendran, B.1
-
96
-
-
0742272509
-
Toll-like receptors and dendritic cells: for whom the bug tolls
-
Reis e Sousa C. Toll-like receptors and dendritic cells: for whom the bug tolls. Semin Immunol 2004; 16:27-34.
-
(2004)
Semin Immunol
, vol.16
, pp. 27-34
-
-
Reis e Sousa, C.1
-
97
-
-
3042521047
-
Modulating TH1/TH2 responses with microbes, dendritic cells, and pathogen recognition receptors
-
Pulendran B. Modulating TH1/TH2 responses with microbes, dendritic cells, and pathogen recognition receptors. Immunol Res 2004; 3:187-96.
-
(2004)
Immunol Res
, vol.3
, pp. 187-196
-
-
Pulendran, B.1
-
98
-
-
0344153910
-
Maturation of dendritic cell 2 phenotype by a helminth glycan uses a Toll-like receptor 4-dependent mechanism
-
Thomas PG, Carter MR, Atochina O, Da'dara AA, Piskorska D, McGuire E, Harn DA. Maturation of dendritic cell 2 phenotype by a helminth glycan uses a Toll-like receptor 4-dependent mechanism. J Immunol 2003; 171:5837-41.
-
(2003)
J Immunol
, vol.171
, pp. 5837-5841
-
-
Thomas, P.G.1
Carter, M.R.2
Atochina, O.3
Da'dara, A.A.4
Piskorska, D.5
McGuire, E.6
Harn, D.A.7
-
99
-
-
77953299188
-
Helminths and dendritic cells: sensing and regulating via pattern recognition receptors, Th2 and Treg responses
-
Everts B, Smits HH, Hokke CH, Yazdanbakhsh M. Helminths and dendritic cells: sensing and regulating via pattern recognition receptors, Th2 and Treg responses. Eur J Immunol 2010; 40:1525-37.
-
(2010)
Eur J Immunol
, vol.40
, pp. 1525-1537
-
-
Everts, B.1
Smits, H.H.2
Hokke, C.H.3
Yazdanbakhsh, M.4
-
100
-
-
68149156007
-
Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses
-
Everts B, Perona-Wright G, Smits HH et al. Omega-1, a glycoprotein secreted by Schistosoma mansoni eggs, drives Th2 responses. J Exp Med 2009; 206:1673-80.
-
(2009)
J Exp Med
, vol.206
, pp. 1673-1680
-
-
Everts, B.1
Perona-Wright, G.2
Smits, H.H.3
-
101
-
-
33645846029
-
IPSE/alpha-1: a major immunogenic component secreted from Schistosoma mansoni eggs
-
Schramm G, Gronow A, Knobloch J et al. IPSE/alpha-1: a major immunogenic component secreted from Schistosoma mansoni eggs. Mol Biochem Parasitol 2006; 147:9-19.
-
(2006)
Mol Biochem Parasitol
, vol.147
, pp. 9-19
-
-
Schramm, G.1
Gronow, A.2
Knobloch, J.3
-
102
-
-
68149163162
-
The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1)
-
Steinfelder S, Andersen JF, Cannons JL et al. The major component in schistosome eggs responsible for conditioning dendritic cells for Th2 polarization is a T2 ribonuclease (omega-1). J Exp Med 2009; 206:1681-90.
-
(2009)
J Exp Med
, vol.206
, pp. 1681-1690
-
-
Steinfelder, S.1
Andersen, J.F.2
Cannons, J.L.3
-
103
-
-
33646265778
-
IPSE/alpha-1, a major secretory glycoprotein antigen from schistosome eggs, expresses the Lewis X motif on core-difucosylated N-glycans
-
Wuhrer M, Balog CI, Catalina MI et al. IPSE/alpha-1, a major secretory glycoprotein antigen from schistosome eggs, expresses the Lewis X motif on core-difucosylated N-glycans. FEBS J 2006; 273:2276-92.
-
(2006)
FEBS J
, vol.273
, pp. 2276-2292
-
-
Wuhrer, M.1
Balog, C.I.2
Catalina, M.I.3
-
104
-
-
33846918192
-
Schistosoma mansoni soluble egg antigens are internalized by human dendritic cells through multiple C-type lectins and suppress TLR-induced dendritic cell activation
-
van Liempt E, van Vliet SJ, Engering A, Garcia Vallejo JJ, Bank CM, Sanchez-Hernandez M, van Kooyk Y, van DI. Schistosoma mansoni soluble egg antigens are internalized by human dendritic cells through multiple C-type lectins and suppress TLR-induced dendritic cell activation. Mol Immunol 2007; 44:2605-15.
-
(2007)
Mol Immunol
, vol.44
, pp. 2605-2615
-
-
van Liempt, E.1
van Vliet, S.J.2
Engering, A.3
Garcia Vallejo, J.J.4
Bank, C.M.5
Sanchez-Hernandez, M.6
van Kooyk, Y.7
van, D.I.8
-
105
-
-
60949099835
-
Calreticulin from the intestinal nematode Heligmosomoides polygyrus is a Th2-skewing protein and interacts with murine scavenger receptor-A
-
Rzepecka J, Rausch S, Klotz C et al. Calreticulin from the intestinal nematode Heligmosomoides polygyrus is a Th2-skewing protein and interacts with murine scavenger receptor-A. Mol Immunol 2009; 46:1109-19.
-
(2009)
Mol Immunol
, vol.46
, pp. 1109-1119
-
-
Rzepecka, J.1
Rausch, S.2
Klotz, C.3
-
106
-
-
9244249137
-
Selective maturation of dendritic cells by Nippostrongylus brasiliensis-secreted proteins drives Th2 immune responses
-
Balic A, Harcus Y, Holland MJ, Maizels RM. Selective maturation of dendritic cells by Nippostrongylus brasiliensis-secreted proteins drives Th2 immune responses. Eur J Immunol 2004; 34:3047-59.
-
(2004)
Eur J Immunol
, vol.34
, pp. 3047-3059
-
-
Balic, A.1
Harcus, Y.2
Holland, M.J.3
Maizels, R.M.4
-
107
-
-
0033922732
-
Proteins secreted by the parasitic nematode Nippostrongylus brasiliensis act as adjuvants for Th2 responses
-
Holland MJ, Harcus YM, Riches PL, Maizels RM. Proteins secreted by the parasitic nematode Nippostrongylus brasiliensis act as adjuvants for Th2 responses. Eur J Immunol 2000; 30:1977-87.
-
(2000)
Eur J Immunol
, vol.30
, pp. 1977-1987
-
-
Holland, M.J.1
Harcus, Y.M.2
Riches, P.L.3
Maizels, R.M.4
-
108
-
-
78149261083
-
Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-beta pathway
-
Grainger JR, Smith KA, Hewitson JP et al. Helminth secretions induce de novo T cell Foxp3 expression and regulatory function through the TGF-beta pathway. J Exp Med 2010; 207:2331-41.
-
(2010)
J Exp Med
, vol.207
, pp. 2331-2341
-
-
Grainger, J.R.1
Smith, K.A.2
Hewitson, J.P.3
-
109
-
-
33144476468
-
Regulatory T cells induced by parasites and the modulation of allergic responses
-
Wilson MS, Maizels RM. Regulatory T cells induced by parasites and the modulation of allergic responses. Chem Immunol Allergy 2006; 90:176-95.
-
(2006)
Chem Immunol Allergy
, vol.90
, pp. 176-195
-
-
Wilson, M.S.1
Maizels, R.M.2
-
110
-
-
58149242734
-
The danger within: endogenous danger signals, atopy and asthma
-
Willart MA, Lambrecht BN. The danger within: endogenous danger signals, atopy and asthma. Clin Exp Allergy 2009; 39:12-9.
-
(2009)
Clin Exp Allergy
, vol.39
, pp. 12-19
-
-
Willart, M.A.1
Lambrecht, B.N.2
-
111
-
-
59049100417
-
Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein
-
Trompette A, Divanovic S, Visintin A et al. Allergenicity resulting from functional mimicry of a Toll-like receptor complex protein. Nature 2009; 457:585-8.
-
(2009)
Nature
, vol.457
, pp. 585-588
-
-
Trompette, A.1
Divanovic, S.2
Visintin, A.3
-
112
-
-
64149087970
-
House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells
-
Hammad H, Chieppa M, Perros F, Willart MA, Germain RN, Lambrecht BN. House dust mite allergen induces asthma via Toll-like receptor 4 triggering of airway structural cells. Nat Med 2009; 15:410-6.
-
(2009)
Nat Med
, vol.15
, pp. 410-416
-
-
Hammad, H.1
Chieppa, M.2
Perros, F.3
Willart, M.A.4
Germain, R.N.5
Lambrecht, B.N.6
-
113
-
-
79952313959
-
Mite allergen is a danger signal for the skin via activation of inflammasome in keratinocytes
-
Dai X, Sayama K, Tohyama M et al. Mite allergen is a danger signal for the skin via activation of inflammasome in keratinocytes. J Allergy Clin Immunol 2011; 127:806-14.
-
(2011)
J Allergy Clin Immunol
, vol.127
, pp. 806-814
-
-
Dai, X.1
Sayama, K.2
Tohyama, M.3
-
114
-
-
79955040263
-
The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses
-
Kouzaki H, Iijima K, Kobayashi T, O'Grady SM, Kita H. The danger signal, extracellular ATP, is a sensor for an airborne allergen and triggers IL-33 release and innate Th2-type responses. J Immunol 2011; 186:4375-87.
-
(2011)
J Immunol
, vol.186
, pp. 4375-4387
-
-
Kouzaki, H.1
Iijima, K.2
Kobayashi, T.3
O'Grady, S.M.4
Kita, H.5
-
115
-
-
77954311653
-
T-cell polarization depends on concentration of the danger signal used to activate dendritic cells
-
Peters M, Dudziak K, Stiehm M, Bufe A. T-cell polarization depends on concentration of the danger signal used to activate dendritic cells. Immunol Cell Biol 2010; 88:537-44.
-
(2010)
Immunol Cell Biol
, vol.88
, pp. 537-544
-
-
Peters, M.1
Dudziak, K.2
Stiehm, M.3
Bufe, A.4
-
116
-
-
66349089266
-
IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation
-
Ben-Sasson SZ, Hu-Li J, Quiel J, Cauchetaux S, Ratner M, Shapira I, Dinarello CA, Paul WE. IL-1 acts directly on CD4 T cells to enhance their antigen-driven expansion and differentiation. Proc Natl Acad Sci U S A 2009; 106:7119-24.
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 7119-7124
-
-
Ben-Sasson, S.Z.1
Hu-Li, J.2
Quiel, J.3
Cauchetaux, S.4
Ratner, M.5
Shapira, I.6
Dinarello, C.A.7
Paul, W.E.8
-
117
-
-
65449144481
-
IL-1-dependent, IL-1R1-independent resistance to gastrointestinal nematodes
-
Humphreys NE, Grencis RK. IL-1-dependent, IL-1R1-independent resistance to gastrointestinal nematodes. Eur J Immunol 2009; 39:1036-45.
-
(2009)
Eur J Immunol
, vol.39
, pp. 1036-1045
-
-
Humphreys, N.E.1
Grencis, R.K.2
-
118
-
-
0037385617
-
IL-1 is required for allergen-specific Th2 cell activation and the development of airway hypersensitivity response
-
Nakae S, Komiyama Y, Yokoyama H et al. IL-1 is required for allergen-specific Th2 cell activation and the development of airway hypersensitivity response. Int Immunol 2003; 15:483-90.
-
(2003)
Int Immunol
, vol.15
, pp. 483-490
-
-
Nakae, S.1
Komiyama, Y.2
Yokoyama, H.3
-
119
-
-
66149171633
-
Purinergic signaling and immune modulation at the schistosome surface?
-
Bhardwaj R, Skelly PJ. Purinergic signaling and immune modulation at the schistosome surface? Trends Parasitol 2009; 25:256-60.
-
(2009)
Trends Parasitol
, vol.25
, pp. 256-260
-
-
Bhardwaj, R.1
Skelly, P.J.2
-
120
-
-
0031205443
-
Selective loss of the calcium ion signaling pathway in T cells maturing toward a T helper 2 phenotype
-
Sloan-Lancaster J, Steinberg TH, Allen PM. Selective loss of the calcium ion signaling pathway in T cells maturing toward a T helper 2 phenotype. J Immunol 1997; 159:1160-8.
-
(1997)
J Immunol
, vol.159
, pp. 1160-1168
-
-
Sloan-Lancaster, J.1
Steinberg, T.H.2
Allen, P.M.3
-
121
-
-
0025288654
-
Evidence implicating utilization of different T cell receptor-associated signaling pathways by TH1 and TH2 clones
-
Gajewski TF, Schell SR, Fitch FW. Evidence implicating utilization of different T cell receptor-associated signaling pathways by TH1 and TH2 clones. J Immunol 1990; 144:4110-20.
-
(1990)
J Immunol
, vol.144
, pp. 4110-4120
-
-
Gajewski, T.F.1
Schell, S.R.2
Fitch, F.W.3
-
122
-
-
47949123507
-
Th1 and Th2 cells form morphologically distinct immunological synapses
-
Thauland TJ, Koguchi Y, Wetzel SA, Dustin ML, Parker DC. Th1 and Th2 cells form morphologically distinct immunological synapses. J Immunol 2008; 181:393-9.
-
(2008)
J Immunol
, vol.181
, pp. 393-399
-
-
Thauland, T.J.1
Koguchi, Y.2
Wetzel, S.A.3
Dustin, M.L.4
Parker, D.C.5
-
123
-
-
62749120029
-
Signals for the execution of Th2 effector function
-
Fowell DJ. Signals for the execution of Th2 effector function. Cytokine 2009; 46:1-6.
-
(2009)
Cytokine
, vol.46
, pp. 1-6
-
-
Fowell, D.J.1
-
124
-
-
33344458030
-
T cells use two directionally distinct pathways for cytokine secretion
-
Huse M, Lillemeier BF, Kuhns MS, Chen DS, Davis MM. T cells use two directionally distinct pathways for cytokine secretion. Nat Immunol 2006; 7:247-55.
-
(2006)
Nat Immunol
, vol.7
, pp. 247-255
-
-
Huse, M.1
Lillemeier, B.F.2
Kuhns, M.S.3
Chen, D.S.4
Davis, M.M.5
-
125
-
-
77952585347
-
Sustained signaling by canonical helper T cell cytokines throughout the reactive lymph node
-
Perona-Wright G, Mohrs K, Mohrs M. Sustained signaling by canonical helper T cell cytokines throughout the reactive lymph node. Nat Immunol 2010; 11:520-6.
-
(2010)
Nat Immunol
, vol.11
, pp. 520-526
-
-
Perona-Wright, G.1
Mohrs, K.2
Mohrs, M.3
-
126
-
-
0035555263
-
Deletion of a coordinate regulator of type 2 cytokine expression in mice
-
Mohrs M, Blankespoor CM, Wang ZE et al. Deletion of a coordinate regulator of type 2 cytokine expression in mice. Nat Immunol 2001; 2:842-7.
-
(2001)
Nat Immunol
, vol.2
, pp. 842-847
-
-
Mohrs, M.1
Blankespoor, C.M.2
Wang, Z.E.3
-
127
-
-
0035984591
-
A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells
-
Solymar DC, Agarwal S, Bassing CH, Alt FW, Rao A. A 3' enhancer in the IL-4 gene regulates cytokine production by Th2 cells and mast cells. Immunity 2002; 17:41-50.
-
(2002)
Immunity
, vol.17
, pp. 41-50
-
-
Solymar, D.C.1
Agarwal, S.2
Bassing, C.H.3
Alt, F.W.4
Rao, A.5
-
128
-
-
23344453342
-
A critical control element for interleukin-4 memory expression in T helper lymphocytes
-
Tykocinski LO, Hajkova P, Chang HD et al. A critical control element for interleukin-4 memory expression in T helper lymphocytes. J Biol Chem 2005; 280:28177-85.
-
(2005)
J Biol Chem
, vol.280
, pp. 28177-28185
-
-
Tykocinski, L.O.1
Hajkova, P.2
Chang, H.D.3
-
129
-
-
26644448473
-
A two-step process for cytokine production revealed by IL-4 dual-reporter mice
-
Mohrs K, Wakil AE, Killeen N, Locksley RM, Mohrs M. A two-step process for cytokine production revealed by IL-4 dual-reporter mice. Immunity 2005; 23:419-29.
-
(2005)
Immunity
, vol.23
, pp. 419-429
-
-
Mohrs, K.1
Wakil, A.E.2
Killeen, N.3
Locksley, R.M.4
Mohrs, M.5
-
130
-
-
75749149721
-
Thymic stromal lymphopoietin
-
He R, Geha RS. Thymic stromal lymphopoietin. Ann N Y Acad Sci 2010; 1183:13-24.
-
(2010)
Ann N Y Acad Sci
, vol.1183
, pp. 13-24
-
-
He, R.1
Geha, R.S.2
-
131
-
-
0027139375
-
Regulation of the human IgE response by IL4 and IL13
-
de Vries JE, Punnonen J, Cocks BG, de Waal Malefyt R, Aversa G. Regulation of the human IgE response by IL4 and IL13. Res Immunol 1993; 144:597-601.
-
(1993)
Res Immunol
, vol.144
, pp. 597-601
-
-
de Vries, J.E.1
Punnonen, J.2
Cocks, B.G.3
de Waal Malefyt, R.4
Aversa, G.5
-
132
-
-
2442717844
-
Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology
-
Herbert DR, Holscher C, Mohrs M et al. Alternative macrophage activation is essential for survival during schistosomiasis and downmodulates T helper 1 responses and immunopathology. Immunity 2004; 20:623-35.
-
(2004)
Immunity
, vol.20
, pp. 623-635
-
-
Herbert, D.R.1
Holscher, C.2
Mohrs, M.3
-
133
-
-
0025095669
-
Induction of eosinophilic colonies by interleukin-5 on acute myeloblastic leukaemic cells
-
Motoji T, Okada M, Takanashi M, Masuda M, Tanaka K, Oshimi K, Mizoguchi H. Induction of eosinophilic colonies by interleukin-5 on acute myeloblastic leukaemic cells. Br J Haematol 1990; 74:169-72.
-
(1990)
Br J Haematol
, vol.74
, pp. 169-172
-
-
Motoji, T.1
Okada, M.2
Takanashi, M.3
Masuda, M.4
Tanaka, K.5
Oshimi, K.6
Mizoguchi, H.7
-
134
-
-
0018837746
-
Antigen-induced T cell-replacing factor (TRF). I. Functional characterization of a TRF-producing helper T cell subset and genetic studies on TRF production
-
Takatsu K, Tominaga A, Hamaoka T. Antigen-induced T cell-replacing factor (TRF). I. Functional characterization of a TRF-producing helper T cell subset and genetic studies on TRF production. J Immunol 1980; 124:2414-22.
-
(1980)
J Immunol
, vol.124
, pp. 2414-2422
-
-
Takatsu, K.1
Tominaga, A.2
Hamaoka, T.3
-
135
-
-
0037775352
-
IL-13 effector functions
-
Wynn TA. IL-13 effector functions. Annu Rev Immunol 2003; 21:425-56.
-
(2003)
Annu Rev Immunol
, vol.21
, pp. 425-456
-
-
Wynn, T.A.1
-
136
-
-
0036337768
-
IL-4 induces characteristic Th2 responses even in the combined absence of IL-5, IL-9, and IL-13
-
Fallon PG, Jolin HE, Smith P, Emson CL, Townsend MJ, Fallon R, McKenzie AN. IL-4 induces characteristic Th2 responses even in the combined absence of IL-5, IL-9, and IL-13. Immunity 2002; 17:7-17.
-
(2002)
Immunity
, vol.17
, pp. 7-17
-
-
Fallon, P.G.1
Jolin, H.E.2
Smith, P.3
Emson, C.L.4
Townsend, M.J.5
Fallon, R.6
McKenzie, A.N.7
-
137
-
-
69249150516
-
T-helper type 2-driven inflammation defines major subphenotypes of asthma
-
Woodruff PG, Modrek B, Choy DF et al. T-helper type 2-driven inflammation defines major subphenotypes of asthma. Am J Respir Crit Care Med 2009; 180:388-95.
-
(2009)
Am J Respir Crit Care Med
, vol.180
, pp. 388-395
-
-
Woodruff, P.G.1
Modrek, B.2
Choy, D.F.3
-
138
-
-
77949503208
-
Narrative review: the role of Th2 immune pathway modulation in the treatment of severe asthma and its phenotypes
-
Levine SJ, Wenzel SE. Narrative review: the role of Th2 immune pathway modulation in the treatment of severe asthma and its phenotypes. Ann Intern Med 2010; 152:232-7.
-
(2010)
Ann Intern Med
, vol.152
, pp. 232-237
-
-
Levine, S.J.1
Wenzel, S.E.2
-
139
-
-
0035749672
-
Cytokine modulators for allergic diseases
-
Barnes PJ. Cytokine modulators for allergic diseases. Curr Opin Allergy Clin Immunol 2001; 1:555-60.
-
(2001)
Curr Opin Allergy Clin Immunol
, vol.1
, pp. 555-560
-
-
Barnes, P.J.1
-
140
-
-
35348909044
-
Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies
-
Wenzel S, Wilbraham D, Fuller R, Getz EB, Longphre M. Effect of an interleukin-4 variant on late phase asthmatic response to allergen challenge in asthmatic patients: results of two phase 2a studies. Lancet 2007; 370:1422-31.
-
(2007)
Lancet
, vol.370
, pp. 1422-1431
-
-
Wenzel, S.1
Wilbraham, D.2
Fuller, R.3
Getz, E.B.4
Longphre, M.5
|