Constitutive ablation of dendritic cells breaks self-tolerance of CD4 T cells and results in spontaneous fatal autoimmunity

Journal of Experimental Medicine

Volumn 206, Issue 3, 2009, Pages 549-559

  Ohnmacht, Caspar ^a   Pullner, Andrea ^a   King, Susan B S ^a   Drexler, Ingo ^b   Meier, Stefanie ^a   Brocker, Thomas ^a   Voehringer, David ^a  

^a LUDWIG MAXIMILIANS UNIVERSITY   (Germany)

^b TECHNICAL UNIVERSITY OF MUNICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

AUTOANTIBODY; CRE RECOMBINASE; DIPHTHERIA TOXIN; GLYCOPROTEIN P 15095; GAMMA INTERFERON; INTEGRASE; INTERLEUKIN 17;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; AUTOIMMUNE DISEASE; CD4+ T LYMPHOCYTE; CONTROLLED STUDY; DENDRITIC CELL; DISEASE SEVERITY; ENTERITIS; GENE CASSETTE; HYPERIMMUNOGLOBULINEMIA; IMMUNOLOGICAL TOLERANCE; LANGERHANS CELL; LYMPHOCYTIC INFILTRATION; MOUSE; NEUTROPHILIA; NONHUMAN; PRIORITY JOURNAL; SPLENOMEGALY; STEADY STATE; TH1 CELL; WEIGHT REDUCTION; WILD TYPE; ANIMAL; ANTIBODY SPECIFICITY; AUTOIMMUNITY; BIOSYNTHESIS; CELL PROLIFERATION; CYTOLOGY; HYPERGAMMAGLOBULINEMIA; IMMUNOLOGY; METABOLISM; PATHOLOGY; PHENOTYPE;

ANIMALS; ANTIGENS, CD11C; AUTOANTIBODIES; AUTOIMMUNITY; CD4-POSITIVE T-LYMPHOCYTES; CELL PROLIFERATION; DENDRITIC CELLS; DIPHTHERIA TOXIN; HYPERGAMMAGLOBULINEMIA; INTEGRASES; INTERFERON-GAMMA; INTERLEUKIN-17; MICE; ORGAN SPECIFICITY; PHENOTYPE; SELF TOLERANCE;

EID: 63449108301     PISSN: 00221007     EISSN: 15409538     Source Type: Journal    
DOI: 10.1084/jem.20082394     Document Type: Article

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